LOCUS       DARYUW010000001       102855 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYUW010000001 DARYUW010000000
VERSION     DARYUW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102855
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(152..409)
                     /locus_tag="TVW11_000001"
     CDS             complement(152..409)
                     /locus_tag="TVW11_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1364160.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(946..2985)
                     /locus_tag="TVW11_000002"
     CDS             complement(946..2985)
                     /locus_tag="TVW11_000002"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1364161.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(3351..4262)
                     /gene="glyQ"
                     /locus_tag="TVW11_000003"
     CDS             complement(3351..4262)
                     /gene="glyQ"
                     /locus_tag="TVW11_000003"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1364162.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(4628..5161)
                     /locus_tag="TVW11_000004"
     CDS             complement(4628..5161)
                     /locus_tag="TVW11_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1364163.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(5428..5652)
                     /locus_tag="TVW11_000005"
                     /pseudo
     CDS             complement(5428..5652)
                     /locus_tag="TVW11_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(5682..6521)
                     /locus_tag="TVW11_000006"
     CDS             complement(5682..6521)
                     /locus_tag="TVW11_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1364164.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(6608..7756)
                     /gene="nagA"
                     /locus_tag="TVW11_000007"
     CDS             complement(6608..7756)
                     /gene="nagA"
                     /locus_tag="TVW11_000007"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1364165.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(7873..9514)
                     /locus_tag="TVW11_000008"
                     /pseudo
     CDS             complement(7873..9514)
                     /locus_tag="TVW11_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            9705..10451
                     /locus_tag="TVW11_000009"
     CDS             9705..10451
                     /locus_tag="TVW11_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364166.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(11057..11899)
                     /locus_tag="TVW11_000010"
     CDS             complement(11057..11899)
                     /locus_tag="TVW11_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1364167.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            12031..12588
                     /locus_tag="TVW11_000011"
     CDS             12031..12588
                     /locus_tag="TVW11_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1364168.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(12999..13823)
                     /locus_tag="TVW11_000012"
     CDS             complement(12999..13823)
                     /locus_tag="TVW11_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1364169.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(13828..14442)
                     /locus_tag="TVW11_000013"
     CDS             complement(13828..14442)
                     /locus_tag="TVW11_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1364170.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(14603..15475)
                     /locus_tag="TVW11_000014"
     CDS             complement(14603..15475)
                     /locus_tag="TVW11_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1364171.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(15686..16171)
                     /locus_tag="TVW11_000015"
                     /pseudo
     CDS             complement(15686..16171)
                     /locus_tag="TVW11_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(16174..16440)
                     /locus_tag="TVW11_000016"
                     /pseudo
     CDS             complement(16174..16440)
                     /locus_tag="TVW11_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(16442..17374)
                     /locus_tag="TVW11_000017"
     CDS             complement(16442..17374)
                     /locus_tag="TVW11_000017"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1364172.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(17384..17899)
                     /gene="lacB"
                     /locus_tag="TVW11_000018"
     CDS             complement(17384..17899)
                     /gene="lacB"
                     /locus_tag="TVW11_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1364173.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(17915..18340)
                     /gene="lacA"
                     /locus_tag="TVW11_000019"
     CDS             complement(17915..18340)
                     /gene="lacA"
                     /locus_tag="TVW11_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1364174.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            18476..19258
                     /locus_tag="TVW11_000020"
     CDS             18476..19258
                     /locus_tag="TVW11_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1364175.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(19674..20225)
                     /locus_tag="TVW11_000021"
     CDS             complement(19674..20225)
                     /locus_tag="TVW11_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1364176.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(20238..21188)
                     /locus_tag="TVW11_000022"
     CDS             complement(20238..21188)
                     /locus_tag="TVW11_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1364177.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(22059..24290)
                     /locus_tag="TVW11_000023"
     CDS             complement(22059..24290)
                     /locus_tag="TVW11_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1364178.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(24290..24724)
                     /locus_tag="TVW11_000024"
     CDS             complement(24290..24724)
                     /locus_tag="TVW11_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1364179.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            24954..25991
                     /locus_tag="TVW11_000025"
     CDS             24954..25991
                     /locus_tag="TVW11_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1364180.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(26063..26413)
                     /gene="rbfA"
                     /locus_tag="TVW11_000026"
     CDS             complement(26063..26413)
                     /gene="rbfA"
                     /locus_tag="TVW11_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1364181.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(26603..29473)
                     /gene="infB"
                     /locus_tag="TVW11_000027"
     CDS             complement(26603..29473)
                     /gene="infB"
                     /locus_tag="TVW11_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1364182.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(29493..29795)
                     /locus_tag="TVW11_000028"
     CDS             complement(29493..29795)
                     /locus_tag="TVW11_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1364183.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(29788..30084)
                     /locus_tag="TVW11_000029"
     CDS             complement(29788..30084)
                     /locus_tag="TVW11_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1364184.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(30100..31254)
                     /gene="nusA"
                     /locus_tag="TVW11_000030"
     CDS             complement(30100..31254)
                     /gene="nusA"
                     /locus_tag="TVW11_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1364185.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(31364..31846)
                     /gene="rimP"
                     /locus_tag="TVW11_000031"
     CDS             complement(31364..31846)
                     /gene="rimP"
                     /locus_tag="TVW11_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1364186.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            complement(33090..33176)
                     /locus_tag="TVW11_000032"
     tRNA            complement(33090..33176)
                     /locus_tag="TVW11_000032"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(33140..33142),aa:Ser,seq:gga)
     gene            complement(33236..33871)
                     /gene="trmB"
                     /locus_tag="TVW11_000033"
     CDS             complement(33236..33871)
                     /gene="trmB"
                     /locus_tag="TVW11_000033"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1364187.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(33871..34662)
                     /locus_tag="TVW11_000034"
     CDS             complement(33871..34662)
                     /locus_tag="TVW11_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1364188.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(34725..35759)
                     /locus_tag="TVW11_000035"
     CDS             complement(34725..35759)
                     /locus_tag="TVW11_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364189.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(35763..36488)
                     /locus_tag="TVW11_000036"
     CDS             complement(35763..36488)
                     /locus_tag="TVW11_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364190.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            37025..37468
                     /locus_tag="TVW11_000037"
     CDS             37025..37468
                     /locus_tag="TVW11_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364191.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            37921..38340
                     /locus_tag="TVW11_000038"
     CDS             37921..38340
                     /locus_tag="TVW11_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1364192.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            38337..38633
                     /locus_tag="TVW11_000039"
     CDS             38337..38633
                     /locus_tag="TVW11_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1364193.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(38803..40065)
                     /locus_tag="TVW11_000040"
     CDS             complement(38803..40065)
                     /locus_tag="TVW11_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1364194.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(40066..40593)
                     /locus_tag="TVW11_000041"
     CDS             complement(40066..40593)
                     /locus_tag="TVW11_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364195.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(40586..41029)
                     /gene="tsaE"
                     /locus_tag="TVW11_000042"
     CDS             complement(40586..41029)
                     /gene="tsaE"
                     /locus_tag="TVW11_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1364196.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(41395..42855)
                     /locus_tag="TVW11_000043"
     CDS             complement(41395..42855)
                     /locus_tag="TVW11_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1364197.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            43114..43925
                     /locus_tag="TVW11_000044"
                     /pseudo
     CDS             43114..43925
                     /locus_tag="TVW11_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            44277..45269
                     /gene="manX"
                     /locus_tag="TVW11_000045"
     CDS             44277..45269
                     /gene="manX"
                     /locus_tag="TVW11_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1364198.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            45440..46249
                     /locus_tag="TVW11_000046"
     CDS             45440..46249
                     /locus_tag="TVW11_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1364199.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            46265..47176
                     /locus_tag="TVW11_000047"
     CDS             46265..47176
                     /locus_tag="TVW11_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1364200.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            47310..47693
                     /locus_tag="TVW11_000048"
     CDS             47310..47693
                     /locus_tag="TVW11_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1364201.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(48014..49066)
                     /locus_tag="TVW11_000049"
     CDS             complement(48014..49066)
                     /locus_tag="TVW11_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1364202.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            49666..50943
                     /gene="serS"
                     /locus_tag="TVW11_000050"
     CDS             49666..50943
                     /gene="serS"
                     /locus_tag="TVW11_000050"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1364203.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(51175..51945)
                     /locus_tag="TVW11_000051"
     CDS             complement(51175..51945)
                     /locus_tag="TVW11_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1364204.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(51942..52808)
                     /locus_tag="TVW11_000052"
     CDS             complement(51942..52808)
                     /locus_tag="TVW11_000052"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1364205.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(52817..54181)
                     /gene="accC"
                     /locus_tag="TVW11_000053"
     CDS             complement(52817..54181)
                     /gene="accC"
                     /locus_tag="TVW11_000053"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1364206.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(54215..54637)
                     /gene="fabZ"
                     /locus_tag="TVW11_000054"
     CDS             complement(54215..54637)
                     /gene="fabZ"
                     /locus_tag="TVW11_000054"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1364207.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(54634..55107)
                     /locus_tag="TVW11_000055"
     CDS             complement(54634..55107)
                     /locus_tag="TVW11_000055"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1364208.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(55109..56341)
                     /gene="fabF"
                     /locus_tag="TVW11_000056"
     CDS             complement(55109..56341)
                     /gene="fabF"
                     /locus_tag="TVW11_000056"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1364209.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(56357..57091)
                     /gene="fabG"
                     /locus_tag="TVW11_000057"
     CDS             complement(56357..57091)
                     /gene="fabG"
                     /locus_tag="TVW11_000057"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1364210.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(57108..58028)
                     /gene="fabD"
                     /locus_tag="TVW11_000058"
     CDS             complement(57108..58028)
                     /gene="fabD"
                     /locus_tag="TVW11_000058"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1364211.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(58041..59027)
                     /gene="fabK"
                     /locus_tag="TVW11_000059"
     CDS             complement(58041..59027)
                     /gene="fabK"
                     /locus_tag="TVW11_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1364212.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(59222..59446)
                     /locus_tag="TVW11_000060"
     CDS             complement(59222..59446)
                     /locus_tag="TVW11_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1364213.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(59504..60478)
                     /locus_tag="TVW11_000061"
     CDS             complement(59504..60478)
                     /locus_tag="TVW11_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1364214.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(60478..60912)
                     /locus_tag="TVW11_000062"
     CDS             complement(60478..60912)
                     /locus_tag="TVW11_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1364215.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(60992..61783)
                     /locus_tag="TVW11_000063"
     CDS             complement(60992..61783)
                     /locus_tag="TVW11_000063"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1364216.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(62103..63239)
                     /gene="dnaJ"
                     /locus_tag="TVW11_000064"
     CDS             complement(62103..63239)
                     /gene="dnaJ"
                     /locus_tag="TVW11_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1364217.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(63396..65225)
                     /gene="dnaK"
                     /locus_tag="TVW11_000065"
     CDS             complement(63396..65225)
                     /gene="dnaK"
                     /locus_tag="TVW11_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1364218.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(65630..66199)
                     /gene="grpE"
                     /locus_tag="TVW11_000066"
     CDS             complement(65630..66199)
                     /gene="grpE"
                     /locus_tag="TVW11_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1364219.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(66244..67278)
                     /gene="hrcA"
                     /locus_tag="TVW11_000067"
     CDS             complement(66244..67278)
                     /gene="hrcA"
                     /locus_tag="TVW11_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1364220.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(67728..68300)
                     /locus_tag="TVW11_000068"
     CDS             complement(67728..68300)
                     /locus_tag="TVW11_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1364221.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(68297..69040)
                     /locus_tag="TVW11_000069"
     CDS             complement(68297..69040)
                     /locus_tag="TVW11_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1364222.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(69030..69737)
                     /locus_tag="TVW11_000070"
     CDS             complement(69030..69737)
                     /locus_tag="TVW11_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1364223.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(69812..71149)
                     /locus_tag="TVW11_000071"
     CDS             complement(69812..71149)
                     /locus_tag="TVW11_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1364224.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(71164..71430)
                     /locus_tag="TVW11_000072"
     CDS             complement(71164..71430)
                     /locus_tag="TVW11_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1364225.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(71694..72809)
                     /locus_tag="TVW11_000073"
     CDS             complement(71694..72809)
                     /locus_tag="TVW11_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1364226.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(73006..73245)
                     /locus_tag="TVW11_000074"
     CDS             complement(73006..73245)
                     /locus_tag="TVW11_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1364227.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(73296..74240)
                     /locus_tag="TVW11_000075"
     CDS             complement(73296..74240)
                     /locus_tag="TVW11_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1364228.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(74469..75908)
                     /gene="gatB"
                     /locus_tag="TVW11_000076"
     CDS             complement(74469..75908)
                     /gene="gatB"
                     /locus_tag="TVW11_000076"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1364229.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(75908..77374)
                     /gene="gatA"
                     /locus_tag="TVW11_000077"
     CDS             complement(75908..77374)
                     /gene="gatA"
                     /locus_tag="TVW11_000077"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1364230.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(77374..77676)
                     /gene="gatC"
                     /locus_tag="TVW11_000078"
     CDS             complement(77374..77676)
                     /gene="gatC"
                     /locus_tag="TVW11_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1364231.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(78150..78707)
                     /locus_tag="TVW11_000079"
     CDS             complement(78150..78707)
                     /locus_tag="TVW11_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1364232.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(79324..80106)
                     /gene="codY"
                     /locus_tag="TVW11_000080"
     CDS             complement(79324..80106)
                     /gene="codY"
                     /locus_tag="TVW11_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1364233.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(80278..81492)
                     /locus_tag="TVW11_000081"
     CDS             complement(80278..81492)
                     /locus_tag="TVW11_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1364234.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            81779..82231
                     /locus_tag="TVW11_000082"
     CDS             81779..82231
                     /locus_tag="TVW11_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1364235.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEEVDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            complement(82517..83905)
                     /locus_tag="TVW11_000083"
     CDS             complement(82517..83905)
                     /locus_tag="TVW11_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1364236.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            83977..84942
                     /locus_tag="TVW11_000084"
     CDS             83977..84942
                     /locus_tag="TVW11_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1364237.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(85062..87077)
                     /gene="recG"
                     /locus_tag="TVW11_000085"
     CDS             complement(85062..87077)
                     /gene="recG"
                     /locus_tag="TVW11_000085"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1364238.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(87441..88895)
                     /locus_tag="TVW11_000086"
     CDS             complement(87441..88895)
                     /locus_tag="TVW11_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364239.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            complement(88832..89512)
                     /locus_tag="TVW11_000087"
     CDS             complement(88832..89512)
                     /locus_tag="TVW11_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1364240.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            complement(89509..90102)
                     /locus_tag="TVW11_000088"
     CDS             complement(89509..90102)
                     /locus_tag="TVW11_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1364241.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            complement(90083..91765)
                     /locus_tag="TVW11_000089"
     CDS             complement(90083..91765)
                     /locus_tag="TVW11_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364242.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            complement(91758..93521)
                     /locus_tag="TVW11_000090"
     CDS             complement(91758..93521)
                     /locus_tag="TVW11_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1364243.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            complement(93567..94349)
                     /locus_tag="TVW11_000091"
     CDS             complement(93567..94349)
                     /locus_tag="TVW11_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364244.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            complement(94346..95368)
                     /locus_tag="TVW11_000092"
     CDS             complement(94346..95368)
                     /locus_tag="TVW11_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1364245.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            complement(95370..96254)
                     /gene="isdE"
                     /locus_tag="TVW11_000093"
     CDS             complement(95370..96254)
                     /gene="isdE"
                     /locus_tag="TVW11_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1364246.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            complement(96238..97143)
                     /locus_tag="TVW11_000094"
     CDS             complement(96238..97143)
                     /locus_tag="TVW11_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1364247.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            complement(97372..101123)
                     /locus_tag="TVW11_000095"
                     /pseudo
     CDS             complement(97372..101123)
                     /locus_tag="TVW11_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            complement(101325..102740)
                     /locus_tag="TVW11_000096"
     CDS             complement(101325..102740)
                     /locus_tag="TVW11_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1364248.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
BASE COUNT        29514 a        24793 c        20012 g        28536 t
ORIGIN      
        1 gagacagatg gctagtacct cacaattaac catttctaaa aataatgact cttttgtcga
       61 aagacctaat gattaaagct atttgtcttt gtttatcttt ttctcattag taacattaaa
      121 tcatggcaaa atatttatat tcatttaata atcaagattc cggatcatca agtgaccgtc
      181 catgcagacc tttttcgcgc tgcacctgtc ttaatttctc aggagtaaca tcgtttccgt
      241 cttcatcaac aatcttaatg ccttcaatgt gatggcgcac tgagcggcga tagccctcaa
      301 tgtattcctc acgcagcttg gcctgctcta ccttttcagg accagtcaag ccaactgttt
      361 ttttcttttt tgcaagctcg ttaatacgag cgattttttt aggatccata aatcacatat
      421 aagggctgca ccaaaagcag tgagcagctg atgaggcttg atgatgggct agacagcctc
      481 tttaggaccg ttactaggac ctttcaagtc ctttttcacc agctgtgcca gcaagggctg
      541 cctgcaaatg gggctgcctc taatcctttc tctttcgttt gtgacataga gtactgcact
      601 ctttttgtct atatctaagg ctgtgccagc agctgcttag ccttatgctt ctgccaagaa
      661 ggctgtagca agcttcttgt gaaaagctaa aatccatgct cactttacta acagtgttcc
      721 tgatgctttt attgaccact gaccagcaca gctattgcta gcaaagctag cccaagacga
      781 tatctcgtag taagcaagag gactgatttg actaagtatc aattgcttga taagtcttga
      841 gtgcttaggg aaggacttat cccaaggcag gtaatcagtc acctatatca tctagggaat
      901 acgaacagct aacacagggc gatgtgctta atcttacaca gcgaattatt tagtatttaa
      961 tcggtcaaag gccgcaatgg tctctacctt tttaaccagc tctgctaaca gcgctaaacg
     1021 gttacgtcta atagcttcgt cctctgtcat gaccatcgta tggtcaaaaa agtcatcaat
     1081 aactggacta agggcaaaga cctgagctag ctgttctttg gctgatccag atagcactag
     1141 tgaatcaaca gcctgtgcca aagccctttc gtagtcattt tcaaagaggc tagcatcaat
     1201 cagcacagcg tcaactgcct ttttcgctag attaaagacg cgagacagcg actcgacagc
     1261 aggcttgtag gtgtctagct ggcttgccgc agccagagcc tccgctcttg ctaacagttc
     1321 tggtacaaca aagcttgagc tagccagaac tgcttcacgt atatcctttg gaatggctga
     1381 gcccatcatt ttatccacac gtgcacaaat aaagtccagc acctcagcct tatgctgata
     1441 ggtcaagcta tcaaatgaca gctcatatag gctatcaatc agcttatcca taggaatgct
     1501 ccagccgaaa tgctcaagaa ttcggacgat cccctgagtt gcacgacgta gggcataagg
     1561 gtcatttgag cctgacggta tcaaaccaac agagaaaaag gacagcaggg tgtctagctt
     1621 atcagcaaga gcaaggacag caccaacctt tgtttcaggc agctctcctt ctgccgaatt
     1681 tggcaaataa tgctcacgaa ttgctgttgc gacagcagca gcttcgccag ttaaaagggc
     1741 gtatttctcc cccataatgc cctgcaactc atcaaattcc ccaaccatac cagttagaag
     1801 gtcaaattta taaatctggg cagcacgagc gacagcactt ttttctgctt ctgagagccc
     1861 agcctggtca gcaagaaagg ctgcaataac cttggtccgc tccatatgct cagccacaga
     1921 gcctatcttt tcatggaagg tcacatgagc tagcttagca accaaatctt caatagatag
     1981 cttttgatcc tcacgccaga aaaattctcc atcttcaaga cgagcaacaa gcaccttttc
     2041 attgccctta atcacatttt gaagatgctt agcattaccg ttacgaacag aaataaaatt
     2101 cggcattagc ttgccagcct gatcacgcac gacaaaataa cgctgatggt tcttcattga
     2161 ggttactaga acctcttctg ggatttccag gtacttggga tcaaaacttc ccatgaaggc
     2221 agttgggtat tctactaggt tgagcacctc atttaagagg tcctcatcaa tatccacctg
     2281 aaccttttgc tctgcttcga tggctctgat ttgtgctatg atcatctctt gacgctcctt
     2341 agcagaggca atgacaaatt ggctgcgcag gtcagcctca taggaatcag cacttgtaat
     2401 gctagtctct tctccaagga agcgatgtcc gcgactgata cgtcccgaat gaatgtctaa
     2461 aaagtcaagc tccaaaggct catcatctaa cagtacaatc aagctatgca ccggacgaat
     2521 atagtcaaag ctattgttag cccagtgcat gctgactggg aaggtcaagg aagcaagaac
     2581 ctctggcacc gctgctaaga cgtccttagc ctgcttgccc gcttcatgct tggtgacata
     2641 aacgtattcc tcacctttga cctctcggaa ttcgatgtca tcaacagtca agccctttcc
     2701 acgaacaaag ccctgagcgg cttttgaaaa ttgaccatct gcgtcaagag caattttttt
     2761 agagggtccc ttaaaatcct ctgtcagatc agtctgctga tcagctaagc ccagcacacg
     2821 cactgctaaa cgacggggcg ttgaaaagcc ttcgattgcg tcatagctaa gccgattggc
     2881 cttaagaaaa tcagccatac gttcaacaag ctgcttttca ctaggtgtga caacgtaggc
     2941 aggaagctct tcaagaccaa gttctacaag taaatctttt gtcatcatta aaatcctatg
     3001 ggcatcaaat ctaaaagaga agaccaaacc gatcctagca tgccttgggc aagcttggac
     3061 gatcctttgt ctacaagatt tgtcccatct ttctttcctt tcttcaagtt atggggtagg
     3121 tttaggagac caaatcacta gctcctaatc ctgcaagcct gctaataagc tgcctgttag
     3181 acaagatcac ttagcagaaa gactgagctt aacaggacta gtcatcaggc ctttaagtct
     3241 catcgctttt aaaaagcacc taccagatag gtaagctgct agcagcaact agagcttaca
     3301 agatcataca agctgcattg actacaagga actagtttag atccagctgc ttagtcctct
     3361 gccagcaagg ctactcggct agcatcatcc aacaatggga agccaagctt tttacgctct
     3421 gcaacaaagg ttttagcaac gctacgagct aaatgacgaa tccgagcaat atagccagca
     3481 cgctctgtca cagagactgc accacgagcg tcaagcaggt taaaggtatg agagcatttc
     3541 aagacatagt cataggctgg gtggacaagc ccttgtgcta aagcacgctc tgcttctttt
     3601 tcaaatatct caaagttttc aagcagcatg tcctgattgg atacctcaaa ggaatacttg
     3661 gaatgctcat attctggctg aagaaaaatc tcgccgtact taacaccagg tgcccattcg
     3721 atatcataga ccgaatccac ctcttgaatg tatgaggcca agcgctctaa gccataggtg
     3781 acctctgctg tcactggtga tgttgctagg cctcccacct gctggaagta ggtaaattgt
     3841 gtaatctcca taccatcaag ccagacctcc cagccaagtc cagctgagcc ggttgaagga
     3901 ttttcccagt tgtcctcaac aaatcgaata tcatgctcca atggatcaat gccaagtctt
     3961 tcaagagatt gcaggtaaag ctcctgaata ttacttggag aaggcttcat caccacttga
     4021 aattgatggt gctgatacag acgattggga ttttcgccgt atcggccgtc agcaggacga
     4081 cgagatggct ccacataggc agcattccaa ggctctggac caatagcgcg aaggaaggta
     4141 taaggactca tggttcccgc tcctttttca ttgtcatagg cttgcattag catacaacct
     4201 tgatcattcc aatattgctg tagcgtcaaa ataatctctt gaaaggtaag tttgttactc
     4261 atgatttcct ctttctattt tttatgtctt gtcgcaggcg ctaaccaaga gctggctatg
     4321 gcttgactgc tggttggctc ttaaacagct tttcaaagag aaaaaccgcg cctatagcca
     4381 cctacaccta aaggcatagg ggcgtcaaaa cgcggttcca ccctaattta ttacttcatt
     4441 tgatcttgtt gataaacaga tgtcaagcaa gctacaaaca cctgagccta ctctttagag
     4501 aaagcgccaa ccagcagtac catcactcgg ctctcaccag ccccgagctc gctttagatc
     4561 agaaacctgc tattttcttt cctattggtt agtttatcac aaaatcctat gattgtctaa
     4621 tcaactatta tgattttgga cgagttccgt ttggaataat aacctcagac aagagcctat
     4681 tttcttcacg aatgcgcaga taaatcacaa taatatagca agggaaaagc agcattgccg
     4741 taatctgagc atggcaaagc aaagcaatac caaccagctc tggagcaatg tttaaaaagt
     4801 aattggggtg cttaacagtc ttaaagagcc aatgatcgac atatttatgg tcctttgcca
     4861 gcatcagctt cactgtccaa atatctccca agatccgagt tacctcatat agcacagcta
     4921 tcgaaaaaat catcagcagc aagccaagaa agctaatgcc atcaaactta atctgcttga
     4981 gcaatgcctc tgtcacagca aagacataaa tcatgatatg cagcagggtc aaaaacttag
     5041 tgttttgcgc accaaattcc ttgcccccat tagccaggat agccttctcg tttttgatcg
     5101 atttttttaa gaatactaaa cgaatagcaa acatcaagag catcaataac aggataatca
     5161 aagtaagact cctttattct agtttaatct gtttctttca cgaaacacta attaagatta
     5221 tagctaagtt acacagcctt gtcaaaccgt tttcaaaaaa aagatgtctt tctttgatct
     5281 ctaaaaacaa gaggtcgtca cacagcacca tcaagagacc tcatcaaagc tttaaggtcg
     5341 taccaaatca ccatcaaaag acagctccta gactcagtca attcacgagc agcaagcagc
     5401 acccaagagg cattttgcag gcctgaccta cttcgcctgt cgtaaacaca aatcctcaat
     5461 atggtaaata gcgtcacatt gcgctgcaac ctcatcgctg tgtgttgcca ttaagacaat
     5521 catatcctca gtctgacaag ctctgatggc ttgtaagacc tcctgctcag cctcaatatc
     5581 cagggcgcct gttggctcat ctgccaataa cagctgcggt gttttgacca aagcacgagc
     5641 aaggaccact aatgtagctc acttaatccc tgcagctctt gctaaaagtc cttggtatca
     5701 ggatctggga tagctgacat acccggcagg caacgaatgc gctctgaatc ctctggacta
     5761 atctcacaat caaaaatagc catattttct actatgcgtt ccttgtgcac cgacttaggt
     5821 agaggaataa agccctcagc aatagaccaa gcaagggcta gctgagccac tgtcttgttg
     5881 tactttttag ccaatgcctg catggtatca tcggcaaata tctctccttg tcctaatgga
     5941 ccccaggcct ctagcaaaat gtgatgcctg cggcaataat caaccgtctc tttttgatag
     6001 cagccaggcg ccaagcgaat ctgattgact gctggtgtaa tggttgctgt ctgtttaaga
     6061 gcctccagat ggtgaaccat aaagttgctg acaccaatcg agcgaaccaa gcctgcttca
     6121 acagcctcct ccatataaga ccaagctgct gcattggctg cttgccagca atccctaaga
     6181 gccttaggat ttggccaatg aatcagataa aggtctacat actctagtcc aaggcgctca
     6241 agagaggctg ctaaggctgc cttagcgcca tcatagctat gagcatcatt ccagagctta
     6301 gtggtaataa agagttcttc acgaggaacg cccgaatccc gaatggcctg tccaacactt
     6361 ttttcattgt gataaatggc agctgtgtca atatgacgat agcctgcctt aatcgctgct
     6421 agggtggatt ggtaggcctc ctcaccatca gcagccttaa aggtcccaaa gccaagcact
     6481 ggaatagcaa gaccattagc cattgttact gttttaatca tatctaaaac ctcctttttc
     6541 attgtagcac aatgataagc aaagcaaaaa gaattgagct gatcaccagc ccaattcctt
     6601 tgctgtatta agcctcaaag gccttttgac catttaggta ggttgctact aattctaagt
     6661 ccttatcaag aacaataaag tcagcagcat gacctgcctt gatttggcca cagacatctt
     6721 caataccaac cgaagcagct gggacgtaag aggacatgtg aattgcttct gctggacttg
     6781 caattcccca ggcaacaaca tttttaatgc cgtcctttaa ttttaagata gagcctgcta
     6841 gattaccact atccttcaag cgagctgtgc cattttccac aataaccgga aactctccaa
     6901 gcatgtaatc accatctggt gaaccgcctg cacgcataca gtccgtaatc aaagccacat
     6961 gctcatgacc cttttgctgc atcaaaatat cgcaagcaac aggtgagaca tgatgaccat
     7021 cgcagatcag ctctgcaacc gttccaggaa tattataaac agccccaacc ataccaggct
     7081 cacgatgagt caagccacgc atcccattgt aggcatgaac ccaaacacta gctcctgctg
     7141 ctactgcctt tttagcctca gtataggtac catttgagtg acctaaagct actgtgacac
     7201 cctgcttggt cacctcagag acaaatgctt ctacgccatc acgctcagga gccaaagcta
     7261 tttttttgat caagccctta gctgcttttt gccaagctgc aaattcgtct aagcgaggat
     7321 ttttcatata tatcgggttt tgggctccct tgtattcctc agtgaagtaa ggcccttcaa
     7381 aataaatccc ctgaatcttt gctcctttga cctgatcggc aacagaagca acggttgcag
     7441 acacctgctc tagatgctca aaggttgacg ttagggtagt cggtaagaag gaggtcactc
     7501 ctgttgataa gagaccctca ctgatggcat ggagaccttc tgctgaatta tccatcacat
     7561 cagcaccagc atagccatga atatgagtat ctacaagtcc tggtgctatt tgatagcctg
     7621 tataatcaat aacctctgcc tgatcatcaa cagtagccgt ccaataacca aatgtgccat
     7681 tatttagctc caaatagcct gctggcttta cctcgttggg gtaataaaag caatctgctt
     7741 taatatagct tgtcatcttt tttcctccct ttttcgttta ttatacgcct taattcttat
     7801 tttgtaaatg gtatatacca gtccttctgt taaaaagaaa aacctgaata ctatttcaag
     7861 ttttcccttt tattagagct gtcctgaaag tactttctca gctagattta gggcgtggtc
     7921 agtgatacgt gtgtaatgag atataatgtc aataaaatta atccctgcct gtgctgtgca
     7981 ttcgccacga ttgaggcgtt cgatgtgtgt tttacgcaat tgacgctctt tttgctcaat
     8041 cgtcctatga cgctcaacaa tagactgggc tagagccttg tcactatcca caatcgccct
     8101 aatcgcatct aaagttaaac agtgggtcag gtgatacatt tctgttaatt caccacgtgc
     8161 agctgctgaa aagccaatct gctttgctgt aatcccctca atgagagtcg ctaacgactc
     8221 agagtggtca ccaattcgct ccaaatcacg agacgaatcc aacagacctg ctaaaacctc
     8281 attttcacta ggactaaggg cttcattgga aatatcaacg aggtaagtgg tgagctcctc
     8341 atcaatcgta ttgaccgcct tctcatatcg cctcaccttt tcgccaaact tgtcttctgc
     8401 tgtcataatg tagctataag acgcctcaaa agcctgaata gcataggaag ccagatgtac
     8461 caattccttg tgggcatttc ccaaggcaat agaaggagcc tgagtgatta gtaaacggtc
     8521 caaatacaag gcttcatatt tgacgatttc gtcttcacct ggaattaagg tggtcacaag
     8581 ctttgccaga gtgttgataa aaggaagcag caacagggta tttgtgatgt taaaggtccc
     8641 atgtgaaaag gcaatggtca tctcaggtga cagggccaaa acagactgaa gccatagcat
     8701 aaaggaggta aatggcatca gtaaaatcat aaagatgacc gtcccaataa cattaaaaag
     8761 aatatgagca gcagcaacac gcttagctgc aatattagag ccaatagctg ccaaaaccgc
     8821 tgtgatacag gtaccaatgt tagagccaag caaaatagga atcgcaccct gcagggtcaa
     8881 taggccaccc gaaaaaagcc cctgtaaaat accaataatg gccgccgagg attgaatcag
     8941 catggtcaat gctgtcccga taaaaacacc ctgaaagggc ttgtctccaa gcgtcgctag
     9001 gtaatgctga aaggctgaga ctgattttaa aggatccatc gcatcaccca tgaggttgag
     9061 agaaaagaaa attcctccta caccaaaaat gatacgacct aggttattga gttttttatt
     9121 tgacgtgaaa aagagacagg ctgctccaat aaaaatcatg ggcagggcgt aatctcccag
     9181 cttaaaacca atcaaaaagg aggtcactgt tgttccaatg ttggccccca tgacaatacc
     9241 aatcgcctgc tgtagggtta aaaggcctgc agatactagg ccaactgtaa tcaccgtcac
     9301 acccgagcta gactgaatca aagcagacat agctattcca accaagatac caaagaaggg
     9361 gttgcttgtg tacttgtcaa tgtaatacct aagcttatca cctgcggcct gctgcaagtc
     9421 gtctcccatg tatttgatac tgaaaagaaa aagacctaag ccctgtactg ccccccaaaa
     9481 aatgaaacgc aatgtcttgc caatttaccg acacaatatt gtcctcactc gcttatttat
     9541 tctcttctat tttaatgtat ttattcagtt atcacaaggg ttttttaatc cttttaaata
     9601 gtgctcattt agaacctatt ttagagccct agtcctcttt tcattttcct atattcaggg
     9661 tataatagtg ctactcaagc gacaatgatt tcaaaggaga taccatgaga aaaccgacaa
     9721 aagagaccca ctacctcatc attagcttgc ttactattgc cattgcagga ggggcctacc
     9781 ttatttttag tagcctctct ccaaagccag ctaccattac cacccaatct aagggctatg
     9841 agctgttaac taaggctcaa gcattagtca aggaggccga agacaaccca actaaagaag
     9901 ctatcgcaaa ggctcaaaaa gcaattaatc agctaaaaaa gacccagtct aaggaggaat
     9961 tacaggctcg actaacagct atcagcttaa agcacaatca agaagacgtt gctatcaagg
    10021 tcctaaaggc agccgaggac aatccaagcc ctgaacttaa ggaggctgca caaaaagcca
    10081 ttagtaagct ctctgatgag gctaaaaaag ctgccttaca ggctagactt gacgctattg
    10141 gactttcaaa gcctagcact gcacagcctg agactgcaac accagcagca gaaaaaaata
    10201 tagcaccagc tcctgcggct ccacaaataa agcataccac accgtcttct gggggaacga
    10261 cgccagcacc gaaccctaaa cctagtccta agccgaatcc tcagcctagt cctagtccag
    10321 ctccagagaa cccagagcca acgcctagtc ctaaccctca gccaaatcct caaccagaaa
    10381 ccaacacacc tagccctcag ccacctgcaa cagagcaaag tgaaaacact gctccagcag
    10441 gacaaaacta agaaagggca gccagagctg ctgtagctta gttacacttc ttagtacagg
    10501 caataagggc ttagctactg aaataatgct aaacttacga ctaataagct ctctgataaa
    10561 aagaggcttt aggtgattaa aaacagctgg ttctaaaagg attccagctg tttttgtgct
    10621 tcttaattga ttttgaggta ggaagagaag ggaggcttaa tcaagtcgat aagtaatccc
    10681 atatcctctc ctaactctct atcagcttgg ctatgattat agagcggctc acccttacgc
    10741 gctttggtga ttcgtcatgg atattctgac tggcttgacc atttgagttt tttcctcagt
    10801 gtcactccct aagactttta agggactgac gaggtgatta gcatgcacaa caaaaagccc
    10861 ttaaacacac ctttaaggac cttgtattca gcttaatgcc tctatagtat cagggatatt
    10921 tgttaaggca gctctcagct aaagacttgt gataaagacc tatgcctatc cgaccactag
    10981 ctagagtcaa gctgtgcata gctcagcctc tatgactaac agaaaccaga ggcagcgtta
    11041 gatcactttg cttagcttaa acctcatagc ccatgagaag cccttcagct tctgcataga
    11101 agctgcatag gcctgaggct gggctggttt gaatctctgc ttctgggtaa atcgctctaa
    11161 ttttttccgc aatttgctca cagatcttag ggtttttggc gtgggagata aagactcggc
    11221 ctcctttata gcctgccttt tgaatctctt ctaaaacagc tgacactgcc tttttttgac
    11281 ctctggcctt ttgaagcagc tcaagcgtgc cttccttact tgcctgtcct accattctga
    11341 tgtttaataa gccaatcacc ttaccaatga gcttattcag acggccattt ttaaccagat
    11401 tatcaacctt ggccaacaca aaaacaagcc tggttttttc ctgataagct gtaattttct
    11461 caacaacctc atcaaaagaa agcccctgat tgatcaaccg ctctagctct aacacaatca
    11521 aatccatctc accacctgct gacaaagagt caatcacatg gatattggca ttcggatttt
    11581 cctcaagcaa gtcattttga gccaatctag cactattgtg actgcctgag agcgtaccgg
    11641 taatggtaat ggcaatgacg ttatctgctc ccctgtaggc ttgtaaaaaa gcatcaggac
    11701 ttgggcagct tgaggttgct ggcttagagg actgatacat agtctccatc atttgatcaa
    11761 tatctagacc atcatcatct ctaaaaatat ctgaaccaat ctgtagggtt agcggcacac
    11821 gctcaaagcg caggtgattg gattggcttt ttagggctct aatatcgcag cctgaatccg
    11881 atacaatttt ccaggtcatt cgttttcctc ttttccttca tagtctgttt tggttgacaa
    11941 agtaagcatt ttcccataaa attatatcat cactagctag acttttgcta gctaaacgac
    12001 atcagatgta acacttgaaa ggtatttgta atggctggta aaccaatttc taaacagtcc
    12061 cttcaaaatt tagcccactg caatcaggaa tccagacggt taacacgaga agctattgaa
    12121 attgctctgc ttagcttact agaaaagaag cccttaggac acattaccat ttcagaattg
    12181 gtagctagag ctggggtttc aagaaatgct ttttaccgca attacagctc aaaggaggat
    12241 attcttgagt gtctgttgac ttctgttatc agacgtatct ttcgtggact gaaggccttt
    12301 gatctaaaga cacaggccta tcaggcatgg ctttatctgt ttacagaggc caaaaaagaa
    12361 gcgacgctac ttagtattat ctttaaccat cacctgcagc agctcttgac gcagatggtt
    12421 accaagcgtt tgagagccta ccaaaagtgg caggaaaaaa agctgtctca ctacgcactg
    12481 ctcttttgga gcaacgctat tgtctcagtc ctttccaatt ggatttctga tgatatggtt
    12541 gttcctgctg aggagatggc tgctatgggg ctgcccttat tagcctagtt gtctctagat
    12601 cacctatagc tcctagacaa cttcccaaga aaccaagctt gcagcatcag acaggacgct
    12661 tggctggctt gacttaagca ctggcactgc ctaccaagat atgtactagc cctactacag
    12721 gcaaggtgtg acttgtcgct cgctgttgtg cagaggctta aaggctctta catttagctg
    12781 gacaataaaa aaagactgaa gaggctggct ggattagcct gctcttcaat ccagaacctc
    12841 ctttgttgga ggttttttcg tgttttattt ttcagtcgat ctcacacacc taggcttgtg
    12901 gtgttccaag acagctcagc tctagtcaac acctctaaaa ctgagcttat catctctagc
    12961 ttttggaggc cttttctgac gggctggttt gactgtgctt aagagccctt tgtcaatgca
    13021 aattgattaa tggcatgggc cacgcctgct tgatcattgg agaggcttac cttgtcagcg
    13081 acctttttaa ttgcctcatc agcgtttccc atagcgacac ctaagccagc ataggctaac
    13141 atttcaagat catttgctgc atctccaatt gccatcactt ggtctgggcg cagcttcaga
    13201 tcagcggtta attccttcag ggcagaggcc ttggtcacac actccggcat tacctctagg
    13261 attgtttctt gactgcgaac cacactaaag cttgcgctga gtttttctct aacaagagcc
    13321 tcaaaagtat ctagggcagc cttttctccc atgtacatgg cctgaaatat gatttgactg
    13381 ctgttggata actgagatag gttagtagcc tttacctttg taaaaaccaa atcaccatca
    13441 gcctgaacca tatctggaac cttgctatct atcacaagat aatcacgctc tccagtcagg
    13501 gtgaggtaaa tatctgaaaa gggctgagac agctgataaa ggtgctcaat agctgaaaag
    13561 gtcaggcttt gataatgtag cagctcccag cttgggctcc tataggtgct acagccattg
    13621 tttaaaataa ggtactcctc cttatcactc aagcctaatt gctcaaaata cggccttgtc
    13681 ccagactggg ggcggcctgt gcagagaaca acttttatcc cctcttgtgc agctgcttgg
    13741 atagccttaa tattctcttt tggaatgtgc tttttgctat caagcagagt accgtctaaa
    13801 tcaattgcta taagctgaat catcgtctca gtcctctttc cattttatct taggtaggtg
    13861 ccattgtctt ttgttgccaa tcatacgcat gactgtcaat aaaacaacca gcaagtagca
    13921 ttcaacattt gaagtggcca gcttaaaata aagcacaagt gctgctataa tagaccagcc
    13981 agcataaatc tcacttctaa gaacagttgg cttacggcct gccaggacat ctctgaccac
    14041 acctccgcct gcccctgtaa gaaccgctgc tacaataaca gcgcttaagg gctgggctag
    14101 tcgaacagca tgtagagccc cctgaacact aaaggctgca agtccgatag catcagtcag
    14161 caccgctgct ctcacccagc ccttagccac aagcttagga aatagcatga tcagaataat
    14221 agctataaaa gcgcaggcaa attctggtct ttgtccccac aaggcttcaa taggcagccc
    14281 gatcagggta tttctaatag ccccaccacc aaaggctgtg acaaagccta gaataaaaat
    14341 ccccagaaca tcaaactcct cctccatagc gacaatagcg ccggacaagg caaaggctat
    14401 cgttccaata atgcttaaaa gctcccacat atcaattgtc ataactcacc taatgcttcc
    14461 taatccccta ttagtctacc atctttttaa tcaaaatata agtcaaaata agagcaaggt
    14521 cctcaaaaat cctactgatg acctgttttt gtttgcacca aagatttagc ccctatatag
    14581 gctaggctcc tagtagcagg agttaggagc gatagcttgc caaattcaca gccttgttat
    14641 tttccatgag aaagggctct gctgatgtct tggtttgata ggtcttgtat ttatggtaga
    14701 ggtattggta gcaatcctgt ttttgatcaa agaggatggc ttggtagggc tcttggaagg
    14761 acaatttctc aacaaacaga tacttgctct tatactccac tagcactccc acatgaccaa
    14821 taaaaaggta atcaccatct agctgatcgt gaatcacaac agcaagcatt ttggctgggc
    14881 cattaaagct aacagctgag aaatgctctt gcatatgctt ggcatgcacc tgaatatcct
    14941 tggtggcttc cgttttcact cttgaaaaca gctgcttaaa gcgctctgtc tctgcctgtg
    15001 taaagagctg gcttgtggta atggcgtcct cgtccataaa taaaagcgta tcatcactgc
    15061 tggtaggcgc aatcgtcatg ctatccttta gaagcataaa ggtgttgatc cggcaattag
    15121 ttccaatgaa attgccttgc ttttgcgacc acaactcatc gattgctacc acatcatagt
    15181 caggctgctt ctgataggta aaggcccctg tcaagcctgt tttgccaact aggctattat
    15241 attcttgtac accagccata aaggcattga cattagcttc cttcagctga tgtgataggg
    15301 cagccctgac ctcctgctgg ctctttgcac tgttcatgtt ggataggaaa agacgtccct
    15361 tcttagcctg tggctctttt tgctcctgct tgggctgatc agactggtga gaagcctggc
    15421 aagccccaag agttgccgta gcaaggatta gcaaagacat cattactttt ttcatcataa
    15481 cctccttttt aatgagtcat tcaagctggt actctccatc atcaccaaat gagattatca
    15541 gcagctggca gctaatacga ggttgctaca acccacttgt tatctcttta tgtcatgacc
    15601 tcatcgttac cagtatagca taaaaaagaa aagcaccagc tcttgaagcc ttgcagccct
    15661 tgtgccggtg cttttcgtta ggagattaca ctgaaatagt ttttgtggta gctagctgct
    15721 gataccaata agcgcttttt ttagggtaac gcttttgggt ttcaaaatca acatagaaga
    15781 ggccataacg cttatcatag ccatttgacc aagaaaagac gtccatcaag gaccagataa
    15841 aatagccctt aacattagcc ccagcaccga tagcgtctgc aatcacagcc aaatgctgct
    15901 tgatgtaatc aattctagcg tcatcatcaa tcctgccatc aatacaggta tccttgtagc
    15961 caaggtcatt ttcagtgata taaatctttt tatagcctgg atagtctgcc ttgatccgca
    16021 tgatttgatc gtaaagcccc tgtggataga tcatccaatc ccagtctgta cgcggcacat
    16081 caacatcaaa cacgcgttga ccaaccccct ttatctgata tttggagccg cctttttctc
    16141 ccttgccatt atgaatgatt tcggtctcac catggctaat aataagccag acttctcatc
    16201 acgtacctta gtggctggca ggccatattc agggtctagc aggatagagg aggcataggg
    16261 ggttagctcc tctgatacca gagcctttag ggcttcgatt tgccaaggag ctggctctgt
    16321 gtcttggtgg gctgccatca tgcgctttaa agccccgcgt tgatcaaagg ccaaggccga
    16381 aatgattccc ttacgactga ccttttctaa ataagctttt ttgtttcttg ttaatgtcat
    16441 cttatacctc ctctacttga atacggtcaa atagctcatc aaaatgtgcc atgttaacat
    16501 gacctgttct tgtttcttgc gcatttaaca tgcctaaaac attggctttt ttcagaagcg
    16561 tctcatcgtc atctccttct gccaaagccc aagcaatccc tgccacagta gcgtcaccag
    16621 atccaacagg attgactacc tcaattttag gaatggtaac acggtaaaac ctgttatgat
    16681 gtttggcaaa ggccccttgg gcaccaagag aaacaataat ccattctatc ccttcaaata
    16741 aaggttgact caacagagag attaaacgtt cctcatctaa tgtgacaggt tggcctatca
    16801 aatcctccaa ttcttccaaa ttgggtttga taacagttgg tttatctttg ccagccagta
    16861 ccgcttttaa aggagcacca gagcaatcta aaaccacttt gctgccatag actctcgcca
    16921 tagtaatcaa gtcttgataa tagtgagcgg ccagaccctt aggcagactg cctgaaaagg
    16981 ttaagacatc aaactgctta gcaataatac tcatgtggtt caaaaagcct tcggcctcgt
    17041 ccatatcaat gtagggacca gcttccagaa tttccgtctg catgccttca tgtaaaacag
    17101 caatacaatt tctcgtttcc cctttgattt tgaagaattg gttagaaatg ccctgttctt
    17161 gtaactgatg aatgacaaag tcacccagtt tcccaccaat aaatcctgtt gccacaactg
    17221 actgaccagc ttctgctaac actctggtca cattcagccc cttaccaccg gctgtttttg
    17281 tcgttctgtc aacacgatta accgtgtcca aagtcagacg atttagagga taggaaatat
    17341 caatggatgg gtttaaggtt accgttaaaa tcatcgcttc tccctaatcg tggtagtcac
    17401 cgcgatccca tttgtccaaa aactctgtaa agaagtcagg atcttcttgg ttagcattat
    17461 gactttccaa atgggctatc ttagcaatta acttcttatt ctcttcggtt tccttatagt
    17521 ctgcctttat aaaggcctca ataatatcac acatcaaaag ctcacctgtg attttaccac
    17581 caaagccaat cacattggca ttcaattctt ctttggcata aagcgctgtt gtcatatccc
    17641 taacaagcgc tgagcgaatg ccaggaacct tgttgacagc attagtgatc ccaacaccag
    17701 tgccacagat acagacacca agatcagcta ggccattggc gacagcctca ccaacccttt
    17761 tcccaaaaat cgggtaatgg gtgcgggtat ggtcataggt cccacagtca atcacttcat
    17821 agccctttga tttcaaaaaa tctgaaacag ccattttttc atcagtcaca atatgatcac
    17881 agccaatagc aattttcatg atatcctccc ttcgttaagc cattttattg agcatgtcaa
    17941 cacgaatttg atgacggcca ccatcatagt gaccagtcac aaaaccttta gcaatattct
    18001 tagccaattc ttgacccaca atttctgctc ccatggtaat catgcgggca ttgttatgac
    18061 cgcgagtcat gtaggcagag cgttcatctg acacttccgc agcgaccata cctttgattt
    18121 tggtagcgac cataaatggc cctgctccat aagcatcaat cataatgcct agactttcct
    18181 catcagcctt gagcgcccta gcaactgcta gagtattgtc aacaaagtca tcagcaatcg
    18241 ccgtcacatc tgtcacatca aagccttcct gctgcaaaaa gcctttaata gcctctttta
    18301 gatcatttcc atgtgcatct gcacctaaga taatagtcat aggatctcct tttattgtca
    18361 ttaccgttca aaattgttta tttttgtttt gttttttatt attttgttgt ttattgaaaa
    18421 aagagactgt ttatgctatt atgagttaac aatacaccag agaaagtagc ggcctatgct
    18481 taagcgtgaa agattgttaa caattatgga aaaggtaaac gccaacggct ttatcactgt
    18541 cactgatatt atggaaagcc taagggtttc agatatgaca gccaggcgaa atttagatga
    18601 gctagcaagg gctggaaaat tagtacgtat tcgtggcggt gcccagagca tttctatgcc
    18661 tcaaaagctg gagcgttcaa acactgaaaa gctaaccgta caaattgaag ctaaaaaaga
    18721 gattgccaga tacgctagtc agctcattaa tgatggtgag accattttta taggccctgg
    18781 gacaacacta gaatgcttgg ctgaggctct aatcaaccgt cacatccgta ttattaccaa
    18841 cagtctgcct gtttttacga ttcttaataa aagtaaaact gttgatctca ttcttatcgg
    18901 tggtgagtac cgagccatca caggagcctt tgttggcagc cttgcaagcc agaccatctt
    18961 atccttgaag tttgccaagg ccttcatcag ctgcaacggt atttataaaa atgacattgc
    19021 cacctacagt gaaaacgaag gggttattca gcgcctagcc tgtgacaatg ccatcgaaaa
    19081 atacctgctc gctgacaacc aaaagtttaa cgcctatgac ttttacagct tttatcacct
    19141 tgacaatatc gacgccatta tcactgactc caagattagt gacagcgtta aggagcgtta
    19201 ccgccaattt gccaagctct taatcgcaag gccagctgac aatcaggtca gcagctagac
    19261 agcctgcctc tctatctgtt tccaccctga gtccagcagg taaacaaagc tatcaaacga
    19321 aatagcatca taaaagcgca tgaagccact aatattgcaa tggggcttca tgcctttttt
    19381 aacctatcac acgttaagca aagcaaaaag aggctaggac aaaaatcctt cctcttttaa
    19441 aatcgtcaaa ctatagagtt gattggaggg ctcttagccc tcatttttca agcgatgtgg
    19501 cctttttaat cagctgctcg agggtggata acctaatcaa catcgccagg tcatgacgat
    19561 tgaatggtta ttccactctt tttctacgct gagggctgtg aaagggctca tacgacagct
    19621 tagccgcttt ctaacagcta tttacctacc tcacctctta acgagcagac agcctaaatg
    19681 gtatagtcca gctgatcaag actcttttta tggtcaaggt caatatcaag aaaggtcatc
    19741 tgcttgatat tgataaggct ggctacaatt gataccggaa aagcaaccac cgcttgattg
    19801 aagagactaa tattactatt gacaatgcgt tttgctgctg ccaaggctgc attttcctta
    19861 gcaatctcat tttgcaggct caaaaactgc tcagaggagc gcatttccgg ataagcctct
    19921 cctacagcaa aaacctcatt caaggcctgc tcctgtgtcc tcatcacatc atttgtttcc
    19981 tccaaggaaa gcccctgacg cagcttcacg agttcagtaa agaccttttc ctcatgcttg
    20041 gcataggact tagcgatttt tagcatttcc gaaatggtat catatctctt ctcaagagca
    20101 atatcgacat ttcgtttaga ctcctctata acgattcgat acctttctaa tttgtttctc
    20161 actccaataa gccatagtat agtcatgcaa agaataagtg ttaacataga tgacgtcact
    20221 gacataaaaa agcctcctta aagctgatga tttagtgtat ccaacaagcg gtacatctta
    20281 acaagcttgt cttgaatgtt ttcatattcg ctacttaacg atagcttttc aatagcccct
    20341 ctagagctag gggttttcaa gagctgttga ccggaataga aggacacaac aacagtatca
    20401 ccattcatat aaactgctac aggcatctcc tctctccatt catcaagcac tgccagcata
    20461 taaggattta agagcattct agcgcttaat tcatctgtgc agtacacatt gtacgtttca
    20521 ttaaagcgaa tgtcctccat ttccagctgc acctcaccct ttagcttagc cttgtagcca
    20581 ctatggacct tttctctgcc caaaaagccc ttttgagtcg gcacaattct aatataaccc
    20641 ttgatagctg tatgatattt agccagcagc acctgtccgt taaaatcagt gacccgatgc
    20701 cagttatcat cctcattttc ctcatggtag gcataaagat tgcaaaattc tgtctgcatg
    20761 tcatctccaa aaataatatg gcaattactg tcataccatc tggaggacgg tgttgcaagc
    20821 tttagtaagg agagctcaat ccctgaatag taatctatct tgacatctgg cagggcctct
    20881 tgtaaaacag gcagcaaaaa gtgatccaca taggagagct catttgctgt tttgaatgtt
    20941 ttcagccgcg gccaaaccaa gccccccaca aagataatga gaaataaggc aagagatcgg
    21001 tcaaccatgc catacaagat gattgcgcct atcaccattg ccagccagcc cagattattc
    21061 tttctagcat ttccactcat ctcgctttta atttgctcca gcttttggtg atgctcaggc
    21121 gaagcttcta tagctctact cttctccaaa acaataggat ctgtcaatcg cttagtattt
    21181 tcgttcatct cacttactcc agatacttct ccatcagcag cgctcagctg ctcttgataa
    21241 caccagtcac tttatgcttt tgcttaacct ataaatgaca attgcgttac agctaattta
    21301 taatattata ccatttttaa actatttttt ctattattat atttaaatga cgctcaataa
    21361 taaccacata atgttaatat agacatcatc gtgctctttt ttacctaatc atgttgtgag
    21421 caataccccc gtttatcagc ggaaaccata aaggcctcta tgagatcaag actatcagcg
    21481 ccagcccttc ttttggagtc actattcagc ttgttcttcg catgctgtct ttgcctgacc
    21541 atgattcagc tgctcttttt gattgcttgt tatgctcact ttttccgtct catgctgagc
    21601 aagaaaaaac agcaaaccct tgcttggttt actgctcttc tgttgatgtt agtcaaaaaa
    21661 taagccggga gctaatgaca ccctattaac tcataaagcc tgttatcctt tctttgtcat
    21721 agaacaattc acttagtcta ttctcaacca aaatacgaag cctgcttaaa ccgtcttctc
    21781 atattaacag ctaaaaagtg gtgtcaatat gaagaaacct atgatcggta acaataatag
    21841 cacctttaaa tctctcagcg ataatgtaag gttatcctat acctgtcata tttttcggtg
    21901 ctatttgcca tatcaggttg ctatagcact tggtggcttc tggtagcctt aaccaataaa
    21961 tgatctgctt ttttattcct gctctttgtt ttgtttatgc cttttgtcgg cgcaggcctt
    22021 tagctttact atactgacgg taaggtcggt gagagccttt accatttttt atgccttaat
    22081 cgcaaagcat ttaacaccac tgatattgag ctaaggctca tcgcaaagcc agccagcatt
    22141 gggcttaata gagggccgcc aaagacatga aggataccca tagcaacggg gatcattagg
    22201 ctattatagc taaacgccca aaataaattt tgcttaacca ctctgatggt ttgacgactg
    22261 agctctaggc attccaccac atcacgcact gctgaggtca tcaggataac atctgccgcc
    22321 tcaatcgcaa tatccgtacc tgagcctatt gagattccaa tatccgctag ggtcaaggcc
    22381 ggtgcgtcgt tgattccatc accaaccata gcaaccagct gtccgctagc cttcaaatcc
    22441 gcgataatct gggccttttg agcaggcagc acctgactaa agacctgatc aattcccacc
    22501 tcattagcaa tcgcttgagc tgtgagggca ttatctcctg ttagcataac cgtttgaaga
    22561 cctaaatcct gcaaggccct tatagctgcc ttactgtcag cctttagcct atcagcaatc
    22621 agcaataaag cacatagctg attatccttg gcataataca ctacggtttg cccctttaag
    22681 gcagcttgct cggcataggt ctgagcagcg cttatcgcaa tcccctgctg tgacatcagc
    22741 tcactattgc caacagctaa gcgatgctgg tcaatcacac cagtgacacc caagcccaca
    22801 agcgattgaa aatcagtcac agccagcaag tcatagccct tttcctgtgc tactctaaca
    22861 agcgcttctc caagagggtg ctgcgaatac tgctctaagg aagccacctc ctgaagtccc
    22921 tgcttctcac tagcagcaag ggggatgatc cgctgtagct gagcctgacc ctctgtcagc
    22981 gttcctgttt tatcaaaaac aattgtccgc acctgataag ccttctctaa aatatctcct
    23041 cccttaaaaa ggatcccctg ctcagctgca cgacctgagc caaccataat cgcggtggga
    23101 gttgctagac ccagagcaca gggacaagca ataatcaaaa cagctatagc tattgtcagg
    23161 gcaaaatcaa agctctctct cataacaaag agccaaaaaa gaaagctcag cagggataaa
    23221 cttaatacga tagggacaaa gactcctgat accctatcag caagtgcagc aatcggagcc
    23281 ttggcttgct gtgcttgctc caccagctca ataatctgtg aaagcaaggt gtcattgcca
    23341 agcctagagg gctttaccct tagcgctcct tggccattga ttgtgccagc aaacacacta
    23401 tcacctgtca ccttatcaac tggtaggctt tctcctgtta gcatggactc atcaaccgta
    23461 gactgcccct ctactatcag cccatcaaca gccacccgtt cacccggttg aataaagcaa
    23521 atatcctcat tagtcacctg ctctaaggga ataagctgaa gtgctccctc acgaataacc
    23581 ctgacatcag ttacccttaa ggacattagc ttctgaatag cctgcgaggc ccgtcccttg
    23641 gtacgcccct ccaaatagct gccaagggta atcaaggtca gaataaccac aacagattca
    23701 aaataaagct ggtgagcaaa ttgagcagct ccagctacaa tcttaaaaca gctatatgag
    23761 ctgtaaataa aagcaaagct agtggctaag gtcacaagcg aatccatatt aggccgcttc
    23821 tttatcaatg ccttaaagcc attttcatag tactgccgat tcaagaaaag aacaggcagg
    23881 gtcagcaaaa gctgaacaag accatagctt atagcatgcg actgaggtgc tagagcgacc
    23941 ggcagcacca atccaagcat aggtcccatt gcaaggtata gcagcggcag actaaagaga
    24001 gcagaccaca gaaagcgata ccattcattg ctagcctgct cctctaggcg ctctagttgc
    24061 cctctcatat tggtctcatc aagcagctct gctctgtagc ctgcctttct tactgcttga
    24121 atgagctctg ctgagctgag gctgtcagtt gagtagctca ctgatagctt ctcagtcgtc
    24181 acatcaacag ctgccccctc aacacctggc agttgcttaa cagcctgttc aatcgctaga
    24241 gcacaggagg tgcagtgcat tccctctaat agataggtct ctttaacaat catatcctct
    24301 cctttttctg acaatgacat tgtcctggca cacaatcaca ccttacatgg gatactgctc
    24361 cgactttttt agcctctaag agcaactgaa aagcctgaat atcttccagg gtcattgggg
    24421 tatcctttag taatgccagc aacaagcggc tatggtggcg ttgacacatg ccatcaagcc
    24481 tctctcgtag catagcaagc tgtcgcctgt cctgatcaag caaggactgg taaatatagg
    24541 accgtccctg tctatcagcc cttagggctt ttttcttaac caagcgtcca atcaaggtct
    24601 taacggtaga atcagaccaa tggtgctttt catgaagaat agcaataatc tcagagctct
    24661 tcatgctccc attagcccaa acaacacgca taacctccca ttctgcatca gatatcgtat
    24721 ccatattgct acctctcttt catctacggt tttattaagt atagcttatt tgtttacgtt
    24781 tgtaaacaaa taataactaa aaaaggtctc tttatgagaa acagcgtcaa aaaaggactg
    24841 acagctaaag tcagcagcta gcttttaata gtctgaactt tccagtctta tctgattaac
    24901 tttatattga caaaatgagt ccttgtatat tactatatga cagtaatact gtaatgatta
    24961 aggagaaaac attgacgtat cttaaaagac agctaattct actagccctt ctactcacag
    25021 ctataggtag ccaaacaatc gttcaggcca gcacgcgatc ctggaaaagc tggtttattg
    25081 agcaatattt ttggcttaaa cgagacaaaa gctattatgc cgagcaggat gagaatacct
    25141 tctacaacta cgtcaagtca gctggtgaaa agagcaatca aggctttaat ctcactcaaa
    25201 atgaggtcaa cggaacatta aagacagagt atagagacaa catgcaggtt cacagctgga
    25261 atgaaaactc tactaatcca tcaaatcaaa aggtcattct ctatctgcat ggtggctcct
    25321 acctaaacaa cccgacctca taccatattg acatgctcaa aaccttgtca actagccttg
    25381 atgctaagat tgtattgccg atttacccaa aggctccgac ctatacctat gatgtcgcta
    25441 tgccaagatt agttagtctt tatcaggata ttctaaaaag cactaataac aatgctaaca
    25501 atatcaccat catgggagac tcagccggag gcggtctggc actaggtttg gcactagcat
    25561 tgaaaaatga agatattaag cagcctaagg acattatcct gctctcacct tggcttgatg
    25621 tcaccctatc aaatccagag atcccaaatt acgaagcctc tgatcctatc ttatcggctt
    25681 ggggactgcg catagtaggt gatatctggg cacgacgcgg ggaaaataac actaagcacc
    25741 cttatgttag ccctatctat ggagatacaa gcaacctagc acctatcacc atgtttgtag
    25801 gaactcatga aatcttctac ccagacatta caaaatttga tggtatgtta aaacaaaaag
    25861 gacataagca ccagctattt gtcggggaaa agatgaacca tgtttatcct atttacccga
    25921 ttgaagaggc caagacagca caataccaaa tcattgatac cataaaaaaa gagtacgaac
    25981 cccaaaaata ataatacaaa aatgcctacc agacttgagt tttttgccaa agcctggtag
    26041 gcattttctg atcacagcat gactactgtt tcttttctag ctcacggagc aattgatcaa
    26101 ttttattacc ataggcgata gaattgtcct tttcaaaaac caaatccgga attttataca
    26161 tggttaattg cttaccaagc tcacgcttaa tggttcctgt tgcttttttt aagcctattt
    26221 cagccttttg attgtctgaa gctaggtcac tcataatggt atagtaaacc ttagcaactg
    26281 acaaatcgcc cagcatttgc acttctgtga tcgtaacacc ctgcacacgt ggatcacgaa
    26341 cctttttgtg taaaatctcg ttgacctcac gcttgatttc cataccaaca cgatcaatac
    26401 gatgatttgt catggccctt cctttctatt gtcaaatagt acaggctctc agtagctcaa
    26461 taacaagaga aaagcttgat gactttcaag cctttttctc tattaggctg atggctatac
    26521 tattaatagt gactgttcaa atcaagtggt gacattgtct attgtcttga gacgaggcta
    26581 tttaagctac tagccaccac gattatttac gggtaatttc ttccatgacg taagcctcaa
    26641 tggtatcatc gaccttaatg tcattaaagc cttcaatcat caaaccaccc tcttgggcat
    26701 tcccaatctc cttaacatcg tccttataat gcttaagact ggctagctta ccatcaaaga
    26761 taaccacgct atcacgaatg acacgtacac ttgaatcacg cgttacctta ccattaacaa
    26821 ccataaagcc tccgattgtc ccaaccttag agaccttaaa ggtttcacga ataatagcct
    26881 caccaagcat tttttcttga tactcagggt caagcttacc tttcatggct tcctcaacct
    26941 cttcgatcac cttataaata atgctatgca agcgaatctc aacatcgtct gtatcagcct
    27001 gctgacgcgc ctgtggtgtt ggacgcacat tgaagcctat gataacagcg tttgaagcct
    27061 ctgccaaggt cacatctgac tcattgatcg caccgacagc agagtgaaca acatttactc
    27121 gaacgccctc aacatcaatt ttaaggagtg aggctgccaa agcttccaca gagccctgca
    27181 cgtctgcctt gatgatcacg ttaacggttt tgatttcccc tgccttgagg gtatcaaata
    27241 ggttatcaag gctgacacgc tgcgtgtttt gacgttgctt gagaagggca cgcttagcac
    27301 gctcctcccc tgctgcacgc gctgcttttt catcagcata gaccgcaaaa tgatcacccg
    27361 ccataggggt ttcattgaga ccagtaatag ataccggtgt ggacggctca gctgatttca
    27421 cacgacgacc aaggtcattt gtcatggcac gcacacgacc aaaggtgtta ccaacaacga
    27481 ttgggtcttg tacgtgtagg gttccttgtt ggaccagaag tgtcgcaacc gcacccttac
    27541 ctttgtcaag tctagcctca atgaccgtac caatcgcacg aaccgtagga tcagccttta
    27601 gctcttcaac ctcagctacc aaaagcactg tttctagcag ctcatcaatg tttttgttaa
    27661 atttggcaga gatttcaaca aactcacact caccacccca agcagttgag atgatcccat
    27721 gctcagccaa ttctgaaata acacgctcag gattagcccc tggcttgtca atcttgttga
    27781 tggcaacgat aattggaaca ccagccgcct tagaatggtt aatagcttca atggtttgtg
    27841 gcattacccc gtcatcagca gctacaatca aaatggtaat atctgtcact gacgctccac
    27901 gtgcacgcat gcttgtgaag gcagcatgtc ctggtgtatc caagaaggta atcttcttgc
    27961 ctgcctcctc aatctggtaa gctccaatat gctgggtgat ccctcctgct tctcctgttg
    28021 caacacgaga atttctaagg gtatcaagca gggtcgtctt accatgatcg acgtgtccca
    28081 taatggtaac aaccggtgca cgctcaacaa tattctcagg attaaggtag ctatcatcag
    28141 taaagaagcg ctcgatatca gcttcatcaa cctccacctt ggccttagct tcaatgccat
    28201 aatccaccat taagagctca atggtatcac catctaagga ttggttttgc gttgccatca
    28261 cacccatcat aaataatttc ttgacaatct cagccggctc acgcttgatc cgttttgcaa
    28321 tttcagcaac ggtcattcct tctgaatatt caaattcttt tggtaattca tggaatttac
    28381 gctctgttac tggttttgga gctgtgttgc tattcttatg atgcttacct tttttgtttt
    28441 tcttgttgtt attccagtta ctattctttt gatttctcac ttggttttga ctattccaac
    28501 tcttcttatt tttcttttgt ccatcttcta ggccatgatc ccgatcatgc cctttgtctg
    28561 gacgattttg ttttttacga cgcttatcaa ccggttttgc taccgatgca gcagccatac
    28621 tagcaaccga ctcagtagcc ttagctgagg cttcacgatg ctttttgtcc tctgtctgag
    28681 ccttgagggc ggctgcctta gcctcttgcc ttgcctgttg ctctaagcgt ttagcctcct
    28741 cttgctcacg aaagcgtgat tccctttgtc tggcatactc tgcgttttgc tcagccttta
    28801 aggcagcagc acgcgcctta aaatcaatct taggagcacc ggcttgggtc tgcccttgac
    28861 gtcctgtatc ctgttgacga ctattagcgt taaaggaacg gtttttgtca cgattaccag
    28921 cttgtctatg cccatcgttt cggttatttc cagatgatgg cctgttatca aagcgtctat
    28981 ctctttgctg attttgtgac ttgtggccag ctcgctccgt ctgctgacct tgtgatcgtc
    29041 caagttgacg atagtctgac ttgcggtcat tagagcgatt ttgcccagcc tgccgtctcg
    29101 ctacctgctc cttggcacgt gcttcacgct ctgccttgaa attgcggctc tttggcttaa
    29161 cagcaaccgg ctgtgatgct tcttgtgtcg cagcagctgg cttttctgct gctttagagg
    29221 ctgctggctg tggtgtagtg gccttagctg cttttgcttt ttgttctgct acttgcttgt
    29281 cttttgctga acctgcttga acattcttag tcacacctgc tgaaaagcta gaggcaattt
    29341 tgttagcatc tgcttcttcg acgcttgacg catggctttt gacatctaat cctaaggatt
    29401 tagcacgctc aacgacttct ttactacttt tgccaatttc cttggcaatt tcatgtaatc
    29461 ttttctttga caatttgtgt cctcctattc gtctatttca taagagtcct cattttcttt
    29521 gaaaatccag cgtctgcaat ggcaaccacc ttacgaggct tgccaagtgc agcacttaat
    29581 tccagtgcac taaacactgt ggagacttct acattgtaat aattactttt atctgttact
    29641 tttttagtga tatttgggcc agcatcattg gctaaaaaaa caagattgac ttcctgatgt
    29701 cgaatggctt taatgaccaa ttcctcacct gaaatcactt ttttggcccg ctgagccagt
    29761 ccgatcaaat gagataatct atttaaacta ttcaaggcct agctctcttc ttttaacttt
    29821 gtgatcaaca tgtgcaatca cttcatcgta aaagctctct ggcacctcca ttgagaagct
    29881 acgattaaac acctgttttt tctttgccat aagtgcttct tggttatcta gcttgatata
    29941 agcaccacgc ccattttgct tgccggttgg atcaataaaa atctgcccct ccttattttt
    30001 gacaatacga aggaggtcac gcttatcaat gatctcacca gaaacaagcg acttacgtaa
    30061 aggtattttt tttactttag gcataaaaca cctcttttct tacacttcct cgttggttaa
    30121 gagctcctct gtagctactg cttcagtcat tgctgcttct ttttctgctt caaggcgttc
    30181 atattcactg gctgatttga tgtcaatgcg atagcctgtc aaatgagctg ccaaacgaac
    30241 gttttgacca cgacgaccaa tagcaagcga tagcttatta tcaggcacca ccacagtcgc
    30301 acgcttaaga tcgtcatcat caaagagaac catatcaacc tcagcaggtg caatggcatt
    30361 gtagataaat tcagcagggt catctaccca ttggataacg tcaatatttt cttctactgg
    30421 gatctcaagt cctgtcttag catcatagcg ctttggatgg aatttactga taaccttttt
    30481 gatgttgctg ccgccacgac caacaatcgt tccaatcgca tcaacattgg gattgtggct
    30541 acgcacagca accttagtac ggtcaccagc ctcacgagaa acactcataa tctcaacggt
    30601 cccatcaaaa acctctggaa tttcctgttc cataatgcgc ttgatgaact cagggtgact
    30661 acgactaaca aagacgttaa ccccctttgg attgttttcc accttgtaga catagacatc
    30721 aatccgatca tgtgatttga aggtttctcc tgggatttga tcctgatgtg agagctgagc
    30781 ctctaaggaa ccaaggttaa cataaatgaa acgttggtca aaacgctcaa ccgtacccgt
    30841 catgatttca ccttcatgct gcttgtactc attgaaggtg atttctcgca tctgacgacg
    30901 catcctttcc ataatggttt gctttgcaga ctgagcagcc acacgtccaa actcgctgac
    30961 tgattcttca aaacgaatct tatctcctaa ctcataggct gagctaatgg caagggcatc
    31021 gttcaggcta atttccagac ggctatcaaa tacctcttca acaacctcac gaaccgtaaa
    31081 aacctgaaaa tctgctgttt tatcattaaa ttcaatgacg caggattctg cttgaccata
    31141 acgacgttta taagctgatt tcagtgattc agtgactgcc tcaatgatat ctgccttatc
    31201 aatgtgtttt tcttcttcca aaatacggaa ggcttctagc atttctttgc tcataatgtt
    31261 gtctaccttg ctctcaaagc ttggtaaaaa tcctttctta tcttataaat taatccattt
    31321 agggcttagc caaccgacta aagcaaatcg ctcagcaatt gccttataat ttgacagcta
    31381 aacgagcctt agccactgct tggtaaggaa tctcaactgt tttgtgacgc gtcttatcta
    31441 gataatcaat ggttagggta tcaccatcaa aagccactaa atctccttga aaaaccttca
    31501 ccttatcaat tgcccgatag aggctgacat taatatatga gcctacagca gccttcaagc
    31561 tctcagcagt ctttaatgga cgctctagcc caggactgga aacctccagc atatactgat
    31621 ctgggaaagg gtctggagaa atcgtatcta agagtggact gattaactct gtaagctcag
    31681 cagtatcctc aacggtaatc ccagaagcct tatcaactaa gatactaagg acataatcat
    31741 tgcccatttt gtcgtattcg atgtcgacca attcataggg tgctttaatt acaggttcta
    31801 cgatttgggt aacaatatca ataatagctg tgtttgcgat gttaataacc tcctttactg
    31861 atgactgcta tacctctata gccttgtcct cttgataatc aacacaaaag tggcgagata
    31921 tttctcacca cccttctgta ttgctttaac ctattatacc acaatcaaaa tgaattgcaa
    31981 gaaaatccct actaaaagtg tcaataagac ctcaaaaatc ctatttttta aaaggagagg
    32041 agatctttaa ccttgctttt ttctctttcc ttatcccctc taacctctgt attcatatga
    32101 taaaataaaa tattaaaggg taaaaaagac aactaaaata ttatttgcgg ctgcttcatg
    32161 gtctttacca aaacgaaaaa acctcccatc agaacagatc tatgcatatg cgagagaggc
    32221 cattggtaac tcaataacat cattaataaa gcttaaatta gttcaatttg taattttaat
    32281 accactattt atcggtaata taagtttatc tgaggatatt aaaaatatta atgctatttt
    32341 taaagacagc attagttaat gatataataa aagctgtaat ctccctcatt atatcataaa
    32401 aacgatttca aaaacagact tgtatttcaa gtgacatttg atatacttga agatgggaat
    32461 actgcttgag tggaggcatt gtaggtctag ttcaacgtaa agcagcagct gaaatcgcaa
    32521 aactaatact taaagtgggg atcaagaatg tagcccctgc tgcagctgca gcatcattaa
    32581 tttggagctt tggaagatgc atgtggtttt aatgtcaaaa agatatagta tttgtataac
    32641 atttcttgtt attatttcgc gattcgtttg gtttgccctt acaggaagaa gtccttttta
    32701 tgactttatt gggactatat ttttaggagt agtggtttta ctaattagtc aaaaagtatt
    32761 gaaaaaatta aagtgataaa attattaacc cgacaatagc gaagcagaat gtgatattat
    32821 tgatatgttc cataagatac tttctaatga gattgttagt gcttctcatg ataagtctta
    32881 tgggactttt ttgtactcaa aaagccctat catttccata ctggataaat ccactacaga
    32941 aatgatagag cctaaaatat atgttcacca attggataag ttaaaagaaa aaaatgacca
    33001 tcaggtcaaa agcatttttc aaaatctcaa atttgacggg tgaaaaacag gcgaagactc
    33061 cgaaaccctt gatataccaa taggataaaa ggagaggagg ggattcgaac ccccgagccc
    33121 cgttaaggac tacacgcttt ccaagcgtgc gcactcggcc actatgcgac ctctccaagt
    33181 aaaaggctga tcaactcaac ctcagtagtg tatcatattt ttgtcaaaat agctactaga
    33241 atgttgcttc taggcggtaa ataatctgtc cctttttagc aaatctagcc tcatactcag
    33301 tcatcacatt tccttgataa tcactagcat gtaaatccag ccagacctgc ttgagggtca
    33361 taccgtactg tgaaaagctc gctaggctat actcaaataa gccacgatta tctgttttaa
    33421 aatgaatttc accattttcc ggcaaaatct gcttataagt gtctaaaaag gatttgtagg
    33481 ttagtcgacg cttttcatgc ctgcttttgg gccaaggatc tgaaaaattc aaatacatca
    33541 tatcaacctc accggcatcg aaataattgg tcaggcttga cccatcaacc cgcaagagcc
    33601 taacattagg agcctgagag gctaggacct tatctaaagc atagcttagc actgatagct
    33661 gaatgtcaat gccaatatag ttgatctctg ggtttttcaa cgccatacct gtgataaagg
    33721 ctcccttgcc tgagccaacc tcaatatgga tcggatgatc attaccaaag acctcacacc
    33781 agcgcccctt agcagcctcc ggctctaaaa tgacatagtg aggattgttt tccaagtgct
    33841 cctgcgcacc ctttcgtttt ctaactcgca ttatttcttt ctaaacattt ctctaaattt
    33901 tctaagagcg taaatctctt gattgacatg ctccatatct ctcttatcaa agcaccttaa
    33961 aatctgagtt agataagaga attgagcata ccaaataatc ttttgcatga ccttatcatt
    34021 atttttatag ccataatagg atagccagtc tgcccatcgc gaccgaggaa tatagtggct
    34081 tagcaaataa gccacatcat acattcgatc tgttaggcgc acacaatccc agtccaccaa
    34141 aaaaatcatg ccactggtgg taatcaccca gttgctatgc ttgatatcac catgtacaat
    34201 cgtggccacc tcagagcgaa attcaggtag gctgcgcttt agctccttga cgatagcctg
    34261 taaataagaa ttctgttgaa tttgcaaagg tgcattttgc tcaaagtcta ctaaaaggtc
    34321 ataaggattt tcaattttat agttgagctg aagcaattga ttaaccaact gcttggactt
    34381 gtggaggcgc agcagaatat ggacgatttg cttactgttc atatcctctc tagtcagagt
    34441 acgaccattg agccactctt gagcactcat catatcgcca ttccccatac gctttgccca
    34501 aagcaattgt ggggcaatct gttcctttgc taaggcaggt aggattggtg ttgtattaag
    34561 cttgataaag acgctttcgc catttggata ggtccctttg taggctttgc cactttttcc
    34621 gcgcaaggga gtcaatacaa gatcctgttc ggttgttgtc accttatccc ctccttttct
    34681 atcttctgta accagttatc cctattttac ttgttttaaa ggacttagtc aatcatcttc
    34741 tttaacttgt acggtaagta aagaagattt aataatccca tcgccacaat caacacaaga
    34801 gcattttgcc aagaacggca gagcacaaga ttgacgataa gcatcaaacc acttaattgc
    34861 ctcaacaaag aaagtagatt cctttgctta tgctgtggtt tagtcgggta aagcccactc
    34921 atataatggt aatcataatg atgataaagt gataataact gaaaaagact tagataatga
    34981 aagaccaagg ccaagcctac tgctaaataa gggttggaaa taaaggcaag tgacaagcaa
    35041 ctaagcaaca acagacgtaa ccataaccct agataatcag agctgcgtaa aaatgctctt
    35101 aaatataggt ttgtccaaac ctttttacta tctgccttga taagcttaag tataggattc
    35161 aagtaaggcc tttccttaac cttggttgag attcctttaa catttgtaaa caaagcataa
    35221 aactttaaaa tggcctgctg gcgatctgcc tcaaaagcaa tcgctttttc ccaatcaagc
    35281 cccttggagc tcaaaaagct tgccacctta cgctttaaca gtaagcgctt agccagcacc
    35341 aaaacaccaa gcaatagcac aaaggcaagc aaggaaacac caagcctttg aaacaaagga
    35401 aataaaggta acagcaagac cgtttgaagg ctagaccaaa gaataaagga caagcgctct
    35461 gctgacctga tatgggcaat aacctctgcc tccttggtca gcaaaaaatg ctgatcagcc
    35521 ttttcaagat aggtagcaac tgaccccaga ttaagcaaaa acaagacagc aatcaacaaa
    35581 cctagctgaa tcggtagagg attagcagga aaatgcttga gtagttgact gtactgaaaa
    35641 agaataaagc ccaaaagaaa cagcaagaca agaacaaaat gatcattaaa gacataaggc
    35701 agatacttgg tatgcttgtg ctgaaactcc tgacgacgct tacgaaataa tgccttcata
    35761 gcttacccct cttttgtcag cgctaggtaa atgtcattaa gactagctga agcatctcca
    35821 aagactgcct gcaaatccgc cagagtccct tgtgcacgca cctgtccctg atgcaatatc
    35881 acaaaacggt cacacatttt ttctgccgaa tccagcacat gggtactcat tagaattgac
    35941 ttgccctttg ccttttcaac ctctaaagcc ttaatcaaat cagcaattgc taaggggtca
    36001 agccccaaaa agggctcatc aagaataaaa agactagggt caatgacaaa agcgcaaata
    36061 atcataacct tttgcttcat tcccttagaa aaatgcaccg gaaaccaatc cagcttatcc
    36121 gtcaaacgaa acagctctaa gaagggctca gctcgcttat gtgccagctc cacatcaata
    36181 tcataggcca tagctaccgt attgatatgc tctgctaagg tcagctcctc atacaggctt
    36241 ggtgtttctg ggataaagcc aattttcttg cgataatcag cttcatgctc cgccaaggtt
    36301 aagccatcaa tggaaatcct tcccttatat ggctttaaaa acccaataat ttcattaatc
    36361 gttgttgact taccagcacc atttagacca ataagcccta ctagctctcc atttccgaca
    36421 gaaaagctaa tatccttcaa aactggaata ttaaggtagc ctccagtgac attctcaatg
    36481 tttaacatat catttctttc taatatctaa tctattgtag ctttgcatac tagcttccct
    36541 agatgacagg ttattagcct agacagatag gacttactag gcaatgcttt gtcatcatca
    36601 gcctatccag cgctttgaag cactgataag accaattagc ttgaccctac ttaagaaagc
    36661 tggggcagct aatactaagg gtacacttat attagctatt ataacaaatt tctgcacaga
    36721 gcgttaactg ttttgatcaa tgctcccatc agctaaaaac gctgagtgaa tctgaagtct
    36781 attttaagat catcaagaaa aaggcctagc tataaaaaca gaggctatat tagcttgatc
    36841 tatcagtcct aaccatctat cacatcatat tcgaatgacc tggtgatcct aaatagcagc
    36901 tcatctaagg cgtcatctaa aaaatcatga taatattatc ttattgtatt gaatttttaa
    36961 taatataatg ttatcgttaa catgtaaata agtgttgcgt ctttaatgac aaaggaggta
    37021 tgttatgaat ttgtcacgct ttttaacatt tggtttggta tcactttcag cactttcaat
    37081 ttcaggccta gtccaaacag aggctaaggc taacgaatgg cagactatct ttgaaaagcc
    37141 acaggaggtg gttatcacag atggctggca aactatctct gaaaagcctc aggaagtaag
    37201 cacggctaac gaatggcagg tcagctctga agaagctcaa gagtctgttc ctgataaatt
    37261 ctcacaaaac gaagacccta gcctatgggc tgttcctgat aaattctcac aaaacgagga
    37321 ccctagccta tgggccgttc ctgataaatt ctcacaaaac gaggacccta gcctatgggc
    37381 cgttcctgat aaattctcac aaaatgagga ccctagccta tgggctgttc ctgataaatt
    37441 ctcgcaaaac gaggacccta gcctgtagta aagccatccg cactcgattg aagataaggc
    37501 ctatgttgct gacgcttcaa tctttttttg ttctaaaagc tttctcagcc ttaactgtca
    37561 agaagttcca gcacctcata ctctctgaaa ctcttgtcct tacaaatatt gtgccatgtc
    37621 actaccgtac gatagtgcgc aaatgcacac ctttgacgga cctagcttgc agcaagtagc
    37681 aggcttagtt atgtgcttaa ccataattgc ttagtccatt atcatgattc aaaaggcttt
    37741 gctagtcatg tggtcgataa ccattagcac cagctataaa caattgcaat atagaccagt
    37801 acatgctaag ataactatag tatgagatag ctatggtcac tgagcaacta ctgatttctt
    37861 attctaaaat tattcaacta ctgatttgag ccattgctac gcagacgaaa ggattatcac
    37921 atggaaaatt gtatcttttg cagcattatt agcggtgaga ttccctcctc caaggtttat
    37981 gaggatgagc aggtactcgc ttttttggat atttcgcaaa caacagcggg tcataccctc
    38041 ttgattccta aaaagcatgt ccgaaatatc ctagcaatgg acgccgagac agctagccag
    38101 acctttgaac gattacctaa aatcgctcgc gccattcaaa aagcaacagg tgctactgca
    38161 atgaacatta ttaataataa tgaagagcta gctggtcaga ctgtttttca cgcgcatgtg
    38221 cacctcgttc ctcgctacag ccaagaagac gggatcgcta ttcagtatac aacacatgag
    38281 cctgacttcc cagccctagc agccttggca caacaaatta gtcaggagat tagccaatga
    38341 ctctaaaaac aatgaccaca attggtctca catccgtttt agcctaccaa gtgtatcgta
    38401 aacgtcatca aatcaaagaa actctagtag ccatgcaaac ctctaagaag gctatccagg
    38461 ccgatgttga taggattaag gcaaatctcg ccatcattca aaaggaggct cgaacgcttc
    38521 aagcagcagg aacagaatta gcctacaaat ggcaggcctt taaccaagaa gctcaggccc
    38581 atctgactga aatccaacaa cgtatgagca agtaccagca ggaaacccca taagcctaag
    38641 cagactacca agcctcaagg tgacaaaaaa gggctctatc gtttctgtag tggacaagtc
    38701 cgctataggg attatgggct ctttttgtat gtacaaaaaa gacgaagaaa tcactcacag
    38761 gatcaagcct tgatgagatt tcttcgtttt tttggctgta ccctaaggcg ctgctggcgt
    38821 accagtggtt gcaccacttg attgctgctc tgctggtgag tctgcttgag ggctaggagt
    38881 cacattagct gctcctgact cttgtgtacc agctgttgtg tcctgatagc tgctgctaga
    38941 ggacgtctct gaggaatagg ttgagtactg ggtagatgag tctgtatagg ccggtaggct
    39001 acctgaattg taataatagc tgctatcctg agtagactga gtttttaacg agccataaag
    39061 gttttcgtaa actgtggcag tcgtttttag ctgactaagc ttttcaaggc ctaattcagc
    39121 acgaatgcga ttttggattt ctaaaagatg atctgaggtc acaatttgat aggagccgcc
    39181 atctgacaag gtcgctccct caccctttag ctgataggtt ttgatatttt taagggcgtc
    39241 tgtatagcct aaaagattag gaatggttcg tgatgatatt tcaatgttgg tttgcatatt
    39301 accactaaca gctgacaaga tctttcggta ggagctgata ctgttaaggg caagaatctt
    39361 tttcagcacc ttttgaataa cctcgcgctg acgcttctgc cgaccgtagt ctccctctgg
    39421 atcatcatag cgcattcgag catagaccaa ggcctgctct ccatttatct tgtgagttcc
    39481 tggtgcaacg gtagcctgat actcaggctc attatctgca atagagatag gaaagtcaaa
    39541 ttcattggta acagtaatgc caccaacagc attaaccaaa tcaatgagcc cttgcatgtt
    39601 aatctgaacg tatttgtcaa tcgtgatatt cagcaagtcc tgaacggtca tgatagccat
    39661 ttgggcacca ccagctgcat aagcagcatt cagcttagct tctgctccat tcatctcatt
    39721 atcatttgga cctgacaaag tgatgagaat gtctctttct aagcttgtca tggttgtctt
    39781 tttggtctta gggttaatcg taaccagaat catagaatca ctatttcctt gccaggtaga
    39841 ggttctgtga gacgatcctg tgtcaactcc catcaataga attgaaaagg gctctgtctg
    39901 ttgaatggca tcactttttt tggaggacgt tgcaaaatcc ttaaaggtct ttgacaattc
    39961 tccagttgaa aaggtatagg cattggttag gtaaactccc atagccccca aggtcaacag
    40021 cacaatagct gtcagcatta aaaagatttt ttttccaatt ttcatctatt cacgttccag
    40081 atatttacgc ataaggtaaa catcctgata gtctccattt cttgatttga cgtcctttct
    40141 tttgacgccc tctattttaa agccatattt ctcataaata tgataggcac aagtatttcg
    40201 agcctgaacc tccagctcca aagcacaaag ctgctttgtt tctctggccc aatcaagggt
    40261 agtctccatc aaaagctgtc ctaggccatg attgcggtag ggtttcaaga ccagcataaa
    40321 gcaatcgcca acatagctag tctcacgata tgctttgcca gctatattta gcagaccagc
    40381 taatatatct cccaccttta gcaaaaggca aatatctgtc aaagactcct gactagcctc
    40441 tagaaaacac tcaagcacct ctacggtagc agctatgacg tcctcagtcc ctgtgataaa
    40501 atctgtctca tcagcagctt ctttaattag agtgatcaaa gctgacgcat ctgaggcctt
    40561 ggcctcttcg attgtcacca cctgctcaga catgcttaag ctcctcaaga agtgcctctg
    40621 atcgatgacc atgtgctaga taatcaacct gccggcctgt ttctgttttt gttattaaaa
    40681 tttcaaggta gtcatgcagg gttcccttgg ctaaaagctc gccccactca atcacagtaa
    40741 ccccaccacc aaagataaaa tcatctaaat caatagagtc cggatcatca ccaatccgat
    40801 aaacatctaa atgatacaag ggtagtcttc cctcatattc tcgagcgata gtataggttg
    40861 ggcttttaat catctgatca atccccaaac ccttagcaac ccccttggtc agcgttgttt
    40921 taccagcacc taagtcacca gtcaagacaa gcacatctcc tgcctttagc tgtctaccaa
    40981 tgccttgccc gtaagcgatt aattcattct catttttgct ataaaacata aggctattat
    41041 aacagaaaaa aaacggtctt ccaagcctaa gccagcctgt cagcaaaata ttctaggctc
    41101 gtcagtcctc atataatgtc gtcaaagctc aatcagcttt aacatctcat aaatcaaaag
    41161 agccagcagc aaatcacatg gacctaacat catggcattc tgctgtgata gccagggctg
    41221 aatgctctag aaatcaaccc gcagctctaa aaccttaaga cttagcctaa atataggact
    41281 aggaaaaggt ggcaatgcct atgagcttag aaagtccata gtcccagtcc aaacggtaat
    41341 ccctgtcttt attgtcccag caaaaaagag gcacctaagt acctcattag tcgtttacaa
    41401 taacgctaaa atgataaaat tcaaaacaaa taagaaggtt gctccccaaa gaatcgggtg
    41461 aatctccttg gttttgccct tcacaagctt caccaagcaa tagaaaataa aggagccagc
    41521 cacaccgtat gaaatagagt agcaaagtgc cataaagaaa gcagcaaaga aggacggtag
    41581 ggcaacgtca aagtcgctcc aatcaacatc aaggaaggac gataccatca taaccccgac
    41641 aatgattaag gctggtgcag tcgcagcggc tggaacaatt cccacgatcg gcagcagtaa
    41701 aacagataag acaaagcaga cagcagttga tacagctgtt agacctgtac gtcctccctc
    41761 tgcaatacca gcagcagact caacgtaggt tgtggtattt gaggtgccaa ataaagctcc
    41821 gattgaagta ccaatagcgt cagcaaagag cgcacggtcc atttttgagc taaagccaga
    41881 gctgttttcc aaagctctct catcctcctc agagaaaatc cctgttcgac gaccagtccc
    41941 aacaaaagtt ccaatcgtat caaaggtatc agatagacta aaggcaaaga tcgtcattaa
    42001 aacaagcggc aagcgacttg aatcactaaa cagtgacgcc atgccaccaa aggcagccaa
    42061 gaatgttgtc cctaattcag caaaggctga gctgatgtga ttgtctgcaa aattaacagc
    42121 agaaagatca accactccaa taggaatacc ggctaaagtt gtaactgtaa taccaattag
    42181 gatggctcca cgaacgttct taagcacaag cactgctgtt agcagcagac caaaaactgc
    42241 tagcaaaaca ctcggatcgg tgaaggttga aatagctgga accacaccac cattagcatt
    42301 aacagagaag acgccattag caaatgtttc agcagttgcc ttagctggct caacaccatt
    42361 tacagtaaca atctcagcag atgatagcga aaaggtgatc aggttagcat ttttaaaacc
    42421 tagataagca acaaagactc caatacctcc gccaatagca tgctgcaggc ttactggaat
    42481 agccttgata atgctcttgc gaagctttgt gacagtgata aagatattaa acagaccaca
    42541 aagaaagaca atagccaagg cctcctgcca agaaaatcct aagctaaaaa caacagtgta
    42601 agtaaagaaa gcattaagtc ccataccagg agccaatgcg taaggcacat tagcaaacaa
    42661 acccatgatc aaggtagaga tagcagctgc gatgatggtc gctaaaaaca ccgcttgcga
    42721 cggcataccc gctgcactca aaatacttgg gttaacaaat aagatatatg acatcgcaaa
    42781 aaaagtcgtc acaccagcca tcagctctgt tgaaaccgtc gtgccatttt cttttaactt
    42841 aaaaaacttt tccatttgaa tggagtctcc ttattgatag gcaaaatcaa aaaagccctt
    42901 atctcatcag ataagctttt tctcttaaaa ccaaatgatt attatcgttt ttacgaacga
    42961 tatattcatc gtaacatttt atcgttctat tttcaatagc ttttttcgtt tatttgccat
    43021 gatcgttcaa aatttaacag cctttttttc tattaaccgt ccaagcagca attttctctt
    43081 ccactgatcc taaaatttgt tataatctag tgtatgacta aaaaactaat tgctattgat
    43141 ttagacggga ctttattgca tcacgacaat accatctcta cctatactca aaaaaccatt
    43201 aaggccgtcc aagctaaggg acatgaggtc atcatctcga caggacgtcc ttatcgtatg
    43261 gctattgact actaccttca gctagagcta aagacaccta tgattagctt taatggctct
    43321 ttgacccacc tacctgagca aagatggaaa tacgagcata atgtgactct tgataaggca
    43381 taccttctca aactcctagc agtgcaggag gacttccaga tggactttat tgctagtgag
    43441 taccgaaaag ccttctacat taccatgaat aggcctgaga gcattgaccc caaccttttt
    43501 ggtttgaggc catcacacca gatatggctt tacagatcga caaaatcacg caggatccaa
    43561 atgctcttct catgcaaacg catcatgagg ataagtatgc cctagccaag gccatgcgcg
    43621 ccttcttcaa ggacgaaatt gaggtggact cttggggtgg tcccttaaat atccttgaga
    43681 tgtcccccaa aaacattaat aaggcctata ccttaaaata cctgcttagc atttacaaca
    43741 aggagcctaa ggatttaatc gcctttggtg atgagcataa cgacacagaa atgctggcct
    43801 ttgccggaac cggctatgcc atgaaaaatg ccagccctgt gctgctgccc tttgccgacc
    43861 agcagctagc ttactctaac gaagaggacg gggtcgccag aaaactagaa gagcttttct
    43921 tgtgaaagca aacgaaacca ttgtttttca gaaaacgatg gttttcttaa tgccgtttcc
    43981 gtcaattgat gaaagaattt ctaatatttt cgttattttt cagcatattt tcttttttat
    44041 gcggcataaa aatcccttta ttatcaatat tctacttatt cggcagcgca ttatgaaaat
    44101 tttttcatat ttcgtaagat ttttccgaaa gggcttgatt tttaagtgaa aacgttttaa
    44161 aatagagacg ttcttgaatt tcgttcaagt gaaaaagaat tgccaaatgc tatttggaag
    44221 gagattattc ttcttcattt caacgaaaaa tattttaata aggaggaaga acaagaatgg
    44281 gtatcggtat tattattgcc agccatggta aatttgctga aggtattcat caatctggtt
    44341 ctatgatttt tggtgaacaa gagaaagttc aagttgtgac tttcatgcca aatgaaggac
    44401 cagatgactt gtatggacac ttcaacaatg ctatcgcaca atttgatgct gatgatgaaa
    44461 tccttgtact agctgacctt tggagtggtt ctccatttaa tcaggctagt cgtgtggcag
    44521 gagaaaatcc tgatcgcaaa atggctatca tcactggtct aaatttgcca atgcttattc
    44581 aagcctatac tgagcgtttg atggacgcca atgcaggtgt tgaacaagta gccgcaaaca
    44641 tcattaaaga atctaaggac ggtattaaag cccttcctga agagctcaat ccagttgagg
    44701 aggcttctac agctaatggt ggtggtcaag cgcttcaagg agctattcct aagggaactg
    44761 tcattggaga tggtaagcta aaaatcaacc ttgctcgtat tgacactcgt cttcttcatg
    44821 gtcaggtagc aactgcatgg acaccagctt ctaaggctga tcgtattatt gtagcgtcag
    44881 attctgtggc taaggacgag cttcgtaagc aattgatcaa gcaggcggct cctggtgggg
    44941 ttaaggctaa tgttgttccg atcaataaat tgattgaggc ttctaaggac ccacgctttg
    45001 gcaacactca cgctcttatc ctgtttgaaa ctgttcagga cgcccttcgt gcgattgaag
    45061 gcggcgttga gatcaaagag ctgaacgttg gatcaatagc gcattcaaca ggtaaaacaa
    45121 tggttaacaa cgtattgtct atggacaagg atgacgttgc tgcctttgaa aaattacgtg
    45181 atctaggtgt ttcatttgac gttcgtaagg tgccaaatga ttctaagaaa aacctatttg
    45241 agcttatcca aaaagcaaat gtgcaataag caatttagaa ataagaggta ggcttgttta
    45301 acgcaacaag ctgtctgcct catctacaat gctgcgatga tatgataagc ctgatgattg
    45361 cttctagaca aatcatcatc acttaataac gctttatatt gtccattgac aattgactca
    45421 tatacgaaag gataacaaaa tgtcagatat ttcattaatt tctgcaatct tggtcgttat
    45481 cgttgccttc tttgccggtc ttgaaggtat cttggaccaa tttcaaatgc accaaccact
    45541 tgttgcgtgt accttaatcg gacttgtgac tggtcacctt gaagcaggtg ttatgcttgg
    45601 tggtactctt caaatgcttg cacttggttg ggcaaacatt ggtgctgctg tagctcctga
    45661 cgctgctctt gcatctgttg cagcggctat tatcatggtt aagggtggcg actttactca
    45721 aaaagggatt acctttgcat actcaacagc tattcctctt gcggttgcag gtcttttcct
    45781 tactatgatt gttcgtacca tttcaactgt acttgttcac gctggggaca aggctgcttt
    45841 agagggtaac ttctctgcta tcgagcgctt ccactttgct gcacttcttc ttcaaggctt
    45901 gcgtattgct gtaccagctg cacttcttgt tgctgtgcca actgaggccg ttcaaagtgt
    45961 cttgaaggct atgccagctt ggttgaatga aggtatgcaa atcggtggtg ctatggttgt
    46021 tgccgtaggt tacgctcttg ttatcaacat gatggctaca cgtgaggtat ggccattctt
    46081 cgcacttggt tttgcccttg cagctgtgac ccaattaaca cttatcgcta tgggtgttat
    46141 cggtgtggct attgccttta tctaccttaa cctttcaaaa caaggtggta acggtggagg
    46201 tcgagcaggc tctgctgacc caatcggcga tatcctagaa gactactaga aaggggtaag
    46261 attaatgact gaacaaatta aattaacaaa agctgaccgt aaacgtgttt ggtggcgttc
    46321 acaattcctt caagggtctt ggaactatga gcgtatgcaa aacatgggtt gggcttatgc
    46381 acttatccca gcacttaaaa agctttacac aactaaagaa gatcgtgctg ctgcacttga
    46441 gcgtcatatg gaattcttta acactcaccc atatgtggct gctcctatca tcggggtaac
    46501 gcttgccctt gaagaagaac gtgccaacgg tactgctatt gacaacgctg ctatccaagg
    46561 ggttaagatc ggtatgatgg gacctcttgc aggtatcggt gatcctgtct tctggtttac
    46621 agtgcgtcct atccttggtg ctcttggtgc ttctcttgca caaactggta accttgtcgg
    46681 tccactcctt ttcttctttg gctggaacat tatccgtatg gccttcttgt ggtacactca
    46741 agaatttggc tacaaggctg gatctgaaat caccaaagac atgtcaggtg gtatcctaca
    46801 agacatcact aagggagctt ctatccttgg tatgtttatc cttgctgtcc ttgtacaacg
    46861 ctgggtatct atcaacttta ccatcaacct tccaggcaag cagctttctg aaggtgccta
    46921 tgttgtcttc cctgagggag ccgttaaagg tgctgagcta aaaagtattc ttggacaagc
    46981 tatgggtggc atgagccttg ataaagttca atcacaaacc cttcaagggc aattagactc
    47041 attgatccca ggacttgctg gattactact taccttcctt tgcatgtggt tattgaagaa
    47101 aaaagtatca ccaatcgcaa tcatcattgc cttgtttgca tttggtatca tcgcacacct
    47161 tcttcacatc atgtaataaa aattaaggaa ttgggggctt cccagttcct taatttttgg
    47221 ctgtctagag ccttagcaaa ggccagtatt cagcctgcta caagctatat ttttatgtta
    47281 taatagacaa aaacactaaa ggacttatta tggcacaatc tttaaatcaa agggtgatcc
    47341 ttcagacaac agccgtctcc tatcttggaa tcggaggaaa ggttgggaaa atcttacttg
    47401 gagataaggc tttggaattt tacaatgata aaaacgttga ggacttcatt caaattccct
    47461 ggacggccat taaccaaatc ggtgccaatg tttctggcaa aaaggtcagt cgtcactttg
    47521 aaatctttac cgatcaaggc aaatttctct ttgcttcaaa ggattcagga aaaatcttga
    47581 aggttgctag agaaacaatt ggcaatgaca aggtcatcaa gctaccaacc ttggtccaga
    47641 ccataatagc aaagctattt catcatcaaa aaaaggataa gaaatctcat tgatgggcct
    47701 gccttaattc aatattacgg tcatagacca gcatgataat actcttagac atagcaccat
    47761 agcaatatgt ctaagagttt ttttcgttgc taacaaaaaa gcttgaaaaa caagcttaca
    47821 gaatgtagac aaaccctatc agcgatagaa aaattgaaaa tttagaaatt gactatcata
    47881 taatgaaaac tctggaaaat gctgatatta cagtattttt cagaattctt ttgttttttt
    47941 gattaaaaga aaaagcttga aaaacaagct taagtgaatc ctttctacaa tctaaatcta
    48001 accttattcc tcatcaatct gcaaagggga ttttcttgtc cacccatttc aacaaatttt
    48061 gaaagcctag ttttttaaaa agcatcagcc ttgcctgttc aaccagaaag gacaaaaaat
    48121 aaatcacaat gccgacgcca aatatcagta gtgggtataa aaggatagga gcattgacaa
    48181 agggctctgc aaaatcgcga ataataaatt tgaccagcaa ggggtgtaag tgcaccagat
    48241 aaatacctag agtcgttgga gacacgatca caataaagcg tagcagcagt gtttctgatg
    48301 tcagcttcag cttagcaaaa agaataaata aggcaatagc tcccaaggtc aggctaggtg
    48361 atacatacca gtaccaaata tttcccacca taaatttcat gatataggta actaccaaag
    48421 atcccatata aaccgcaata agaagcttat gactaaacct acttagctct atcctcctta
    48481 gataggctcc gataatgtag agaataatca gccaagtcat ttcaaagccc ttgcttaagg
    48541 aaaattcatc gacctgctgg ttcatcagag ctgggatcaa cgaaaaaata gcaaaaacca
    48601 gcagtaccaa tcggcctagc tgcttattgg ataaggtatt gaggccacca ttgatcatag
    48661 gcataaaaat cagtaaccca aagtaggcgg tgatatacca ataattgcca ctcactatgg
    48721 gaaagagggc ctgacgccaa ttctctaagc taactggaaa gccaaataga gcaaacaaaa
    48781 gggtcatcag aaagctataa aagaagactt gtacccaaat attaacgatt ttggaatatt
    48841 tatagggcga cttaatgccc acatagccac taatcaacgc atagcaattg accgccccat
    48901 aaacaagaac ctgaatcatc caggtaacaa taaaataaga atctgcctca ccttcgacag
    48961 ttgaccgcaa gccgcccttt cccaaaacat gtgtgatcac aatcataaac atggaaatga
    49021 ttcgcaataa atctaaaccg taatggcggt tcttatctaa tgtcattaca tttttacgca
    49081 taatattagt ttaccacaat ttttaatatt taacgatttg attttgtctg acaacgagat
    49141 tttttgtgcc tctgacctaa gctctacttg tcatcagcct tttgtattac tgacgctccg
    49201 tgacagacac atgaaaaagt tttagcaaga aaagaaagct ttctgtattt caaggatatg
    49261 tcttgttttt tatagacttt actataggaa aaacattgaa agtgtctact ctaattccaa
    49321 aataactagt tcgcgcgttt gatgtagctg acactcattt gggagtttac tttttctcct
    49381 tttttgttat aataggtcta gcggataagt agtctggctc tgtctttcag agagtctgtg
    49441 gttgctgaaa acagatagag gagtcatacg aaattctacc gtctaccaat taaatatgaa
    49501 ttaagtgcac agattgtgaa gctggatgga accgcgctta ggcgctccag tgtattcata
    49561 ggctgtgctt ttttatctcg tcagaaataa aaaagcgatc agctagcttt gctcatgcta
    49621 ttttataact gactatctta tcaccagctc aaaggagatt tatttatgct agatcttaag
    49681 cgtattcgta ctgattttga tactgttgct gctaagctca aaacacgtgg tgtgtcagaa
    49741 gctatcctaa cctctctaaa agccttagat gaacagcggc gcaccctgct tgttcaaaca
    49801 gaagagctaa aagcccagcg taatatcgcc tctgctgcta tcgctcaagc caaacgccaa
    49861 aaggaagacg ccagccaaca gattgctgac atgcagcagc tagctgctaa catcaaggca
    49921 attgatgcta agctagctga cattgaccaa gaaattaccg gtatcatcac tgttttgcca
    49981 aatactcccc atgattcagt tcctattgga gctgatgaag aggacaatgt agagattcat
    50041 cgctggggaa agccacgtca gtttgatttt gacatcaagg cgcattggga tcttggagaa
    50101 gccttagata tccttgattg ggagcgtggc gcaaaggtta ccggtgctcg cttcttattc
    50161 tataaaaatc ttggtgcaag gctggagcgt gccctttata acttcatgct tgatgagcac
    50221 ctaaaagagg gctatcaaga aatcattcct ccttatatgg ttaatcatga ctctatgttt
    50281 ggcactggtc aatatccaaa attcaaggag gatacctttg agctagatgg gacaaacttt
    50341 gttcttatcc caactgctga agtcccatta accaattact atcgtggtga catcatagat
    50401 ggtaaggagc tgccaatcta ctttactgca atgagcccat catttcgctc tgaggctggc
    50461 tctgctggcc gcgacactcg tggcttgatt cgcttacacc aattccataa ggtcgaaatg
    50521 gttaagtttg ctaagcccga aacatcttat gaagagctgg aaaaaatgac cgccaatgcc
    50581 gagcatattc tccaaaagct aaagctccct tatcgtgtct tggctctttg tactggggat
    50641 atgggctttt cggccgctaa aacctatgat ttagaggttt ggatccctgc tcaaaacacc
    50701 tatcgcgaaa tctcaagctg ctcaaatacc gaagatttcc aagcacgccg cgcacaaatt
    50761 cgctaccgcg atgaggcaga tggcaaggtt aagctactgc acaccctaaa tggctctggg
    50821 cttgctgtcg gacgtaccgt agctgctatc ctagaaaatt accaaaatga ggacggctca
    50881 gtgacgattc cagaagtgct tcgtccttat atgggtggac tagaggtgat caagccacgt
    50941 taaagccaaa gactggccgg ataaggtgcc aacaagacga ttaatgggct ctatcatttc
    51001 tgtagtagat aaggacacag tagaaatgat agggcttttt tctatgtaca aaaaaggctc
    51061 tttatcaatt gtagggggac aaagagccga ttaatgagat tgatcctaac aataaagaag
    51121 acctctgtaa ctcctagcta actgctagcc ttacagaggt cttttttgat gtccttaata
    51181 ttttctaaag cgctggtagc gctgatccaa taattcctct aagggcttgg cctgtagctg
    51241 agtgatttcg tcaattaagt gtgattttat catctcaaca atctcactcg aaaaataacc
    51301 ccgctccgga ataatccgat caatgacgcc catttgatac agctcagctg cggtaatttt
    51361 catgagctca gcagcttcag tagccctaga gccatccttc cagagaatag aggcaaagcc
    51421 ttctgggcta agaacagcgt acatggtgtt ttccagcatc caaacctgat cagcaacagc
    51481 taaagctaaa gcaccgcctg agccgccttc gccaataata atagcaatga taggaacctt
    51541 gaggtcactc atttccatca agtttctagc aatagcttca ccttgaccgc gctcctcagc
    51601 acctacgccc ggataagctc ctgctgtatt gataaaggta atcactggac gaccaaattt
    51661 ttcagcctgc ttcattaagc gtaaggcctt acgatagccc tcagggtgcg gctgcccaaa
    51721 atttctagcc agattatctt gaagattttt tcctttttga ataccaatca ctgtgaccgg
    51781 ttgatcagcc aaataggcaa tcccaccaac aatagagcca tcatcagcaa actgacgatc
    51841 cccatgcaac tccataaact catcaaaaat caggctggca taatctagag ctgtcattcg
    51901 accctggtca cgcgcttcct ttaatattct tgcgacgtct gtcatgatac acctccatga
    51961 aatgccacca aatgagcaat ccgatcacgc aggtcagtcc gcttcacaat agcgtcaaca
    52021 aagccatgct cttttaagaa ctctgccttt tgaaaatcat ctggtaaatt ttctctaact
    52081 gtcgtctcaa tgacgcgtcg accagcaaaa ccaaccaagg actggggctc tgcaataatc
    52141 atatcaccct ccattgcaaa gctcgctgtc acaccacctg tggtcggatc agttaggata
    52201 gtcaggtaaa aaagcccagc atttgaatgt ttctttatag ctgcagaaac cttagccatc
    52261 tgcatcagac tcataatgcc ctcttgcata cgggctccac cagacgctgt aaaaataaca
    52321 actgggagcc gctcactaat agccagctca aataagcgag tgattttctc accaacaacg
    52381 gtccccatgc ttgccatgat aaaatgcgaa tccatgatgg ctagagcaag cctttgtccc
    52441 ttgaccagag ctgttccagt caggacagcc tcatgcaagc cagtagcctg cctggccttt
    52501 tgcagcttgg cttggtagtc tggaaatctt aatggatcct tggtttcaat atctgtaaac
    52561 aattcctgaa aagagccttc atcaacggtt aaagtcaagc gctcctgagc agaaatccta
    52621 aaattatagg agcaggtcgg acaaatcttt gccggcccca gatccttttg ataaatcatg
    52681 tgcttacagg caggacactt ggcaaataat tcgtctggca cctctggaac attacgactg
    52741 acagagcttt tgagagaatt attgggagta atacggatat atttgtcttt tttactaaat
    52801 aaggccatat ctactcctaa tctttattgt agctgggtaa aaaggtttcc atcaaaaacg
    52861 acgtatcgta atcacccgca atcacttgct tgtctgaaat caagtccatc tgaaaatcaa
    52921 tattggtcat aataccttca atctctaact caaacagagc cctttgcatc ttcatcaaag
    52981 catcaaatcg gttatctcca tgaacgataa tcttagcaat catactatca taataaggcg
    53041 gtatcgtata accactgtaa acagcagaat caatcctaag cccaacacct ccgcttggta
    53101 ggtaaagatc tgtaatctta ccagggcttg gtgcaaaatt aaagcttgga ttttctgcgt
    53161 taatacgaca ctcaatagca tggccagtaa tcacaatatc ctcttgacga actgataaag
    53221 gaagacctgc tgcgatccgc aattgctcct tgacaatgtc aacgcctgta acaaactctg
    53281 ttacggggtg ctctacctga acacgcgtat tcatctccat aaagtaaaaa tcaccgctgg
    53341 cttcatctaa taagaactca attgtgccag cattctcata ggacaccgcc ttggcagcac
    53401 gaacagcagc ttcacccatc ctttgacgca gtgttgtgcc aatcgcaatc gaagggcttt
    53461 cctccagtac cttttgattg ttacgctgta aggagcaatc tctctctcca aggtgtatca
    53521 catgcccctg tgaatcacct aaaatttgca cctcaatatg ccttgccgga taaataacct
    53581 tctccaaata catggcacca ttaccaaagg ctcctaaagc ttcttgacta gcagcgttaa
    53641 aagcagcctc taaatcagcc tcggattcaa cctttcggat tcccttgccg ccaccgcctg
    53701 cagcagcctt tagcattact ggatagccaa tctgccttgc aatctcaaga gcctcttggg
    53761 cattgtaaac ctcgccgtct gagcctggaa taacaggaac acctgcctta atcatctcag
    53821 cgcgggcgtt gattttgtcg cccattttat ccatgacagc tcctgagggg ccaataaact
    53881 tgatgttcat ttcctcgcac atggtcacaa attttgaatt ttcacttaaa aaaccaaacc
    53941 ctgggtggat agcctgcgcc cctgtcacca cagctgctga taagacagaa ttcatattga
    54001 gataggattc ctttgatctt gacggtccaa tacagatggc ttggtctgcc aagatcgtat
    54061 gtaaagcctc tctatcagcc tcagaataaa cagcaactgt ggaaatgcct aattctcgtg
    54121 ctgcacgaat aatccgcact gctatttcac cacgattggc aattaagatt ttgttaaaca
    54181 taggttcttt tttcctccac agacgattag tcttttactg cccaaaagca aaggtcaagg
    54241 tcccactagc tgctaatttg ccatcaacct ctgccttggc ctcaacaact gctattgtcc
    54301 cacgacgctt aataaaccta gctgtcatga ctagctggtc tcccggaacc acctgctttt
    54361 taaattttac cttgtccata ccagcgtaaa aaacaagctt gcctttattt tcctcttttg
    54421 atagctccaa gacgccagca gtttgtgcca aggcctccat gatcaaaaca cctggcatga
    54481 ctggatactg aggaaaatga ccgttaaaga agggctcatt gatagtgaca tttttgatgg
    54541 caacaatttc atcgtctgaa gcctctaaaa ttctatcaac aagcagcatt gggtagcgat
    54601 gtggcaatgc ctcttgaatc tgttttatat ccatcattta atgcgtacca atccttgtcc
    54661 aaactcaacc acgtcctcat tggccactaa aatctctgtc acgataccgt cgcaaggagc
    54721 aggaatctcg ttcatgacct tcatcgcctc aacaattaac aatgtctgtc cctttttaac
    54781 gctatcacca acagtaacaa atggaggctt gtcaggaccg gcagcaagat aggccacacc
    54841 aacaagagga ctgtcaacta cttctccttc tggctcttgc agacctgaag aagcagggat
    54901 tgattcctgt ttagagacaa tctcctgcgt caggctaata ggggctacct cctggtgcaa
    54961 agtaacaggc tcaggagctg gagctgccat cggacggtgc tcatttttac taaataacag
    55021 ctccccatca cttgatttga atgaaaattc gcgtaggctt gacgcatcaa actgtgccat
    55081 caaatccttt atctcttgaa tattcatttt aatcctccca acgcttaaag gctaatacag
    55141 cgttatgacc tccaaagcca aaggtatttg acatggcata acgaatatcg gcttcttttc
    55201 cttggccaaa aataacattt gcttcaatat catctgacag ctcctttgtc ccagctgtca
    55261 ttggaacata attgtgacgt attgcttcta tggttgcaat agcttccaca gcaccagctg
    55321 cccctagtag gtggcctgta aaggacttgg ttgatgagac aggaacctct ttaccaagca
    55381 ctgcaacaat agcctgactt tctccttttt cattagcagg agttgaggtg ccatgagcat
    55441 tcacgtagtc aatagctgct gcatcaatac cggcctcctg caatgctaga ttaatggcct
    55501 tacgagcacc aagtccttct gggtgtggtg aggtcatgtg gtaagcgtca caggtattgc
    55561 cgtagccaac aatctcagct aaaatagtcg caccgcgctt ttgagcatgc tctaagcttt
    55621 ccaaaacaag catacctgat ccttcaccca tgataaaacc gtttcgatcc ttatcaaatg
    55681 gaatagagct gcggcttggg tcctcagttg ttgacaaggc agtcaagctc tggaagcccg
    55741 caatggcaaa ttttgtaatg gctgcctctg atcctccaac catcatcacg tcttgaagac
    55801 caaacttaat tgtacgaaag gcatcgccaa tagcatcgtt tgaagaggca caggctgtat
    55861 tgattgactt acatacgcct tgggcattca gcttcatggc aacattacca gccgccatat
    55921 ttggcaaggc ctttggtaga gtcatcggct taacgcgctt tggtcctttt tcatgtaacc
    55981 gaatcacctg ctcttcaatc tcttgaatgc ctccaatacc agacgctaca ataacaccaa
    56041 agcggtcaga atcaatcgct tcaatatcta ggccagcatg ttcaatcgcc tctgtcgcag
    56101 catataaggc atacaaggaa tacatgtcaa agcgatttag atcctttttg acaaaatact
    56161 tatcaaatgg aaaatcctga atctctgctg cattcttaac agcgaagtca ctcgtatcaa
    56221 attttgtgat aggcttaata ccaatatgac ctgcctttaa gcttgaccaa aactcctctg
    56281 gagtatgccc aattggggaa gtcacgccat aacctgttac aactactctg tttaatgtca
    56341 ttttaatacc tctattttat tgcattgtca tgccgccgtc aatggcaagc acctgaccag
    56401 taatataatc ctgactagct aggaagcttg ctgcctgagc aacctcttgc cccttgccaa
    56461 tacgcttcat tgggatttga tttaagattt gctcttgcat cttttcagaa aggacacctg
    56521 tcatatcaga ttcgatgaag cccggtgcaa tcgcatttac ccgaatgcca cgcgccgcaa
    56581 cctcacgagc aactgacttg gtaaagccaa tcaagcctgc cttggacgct gcataatttg
    56641 cttgaccgat atttcctgtt aggccgacaa cactagacac attgatgata gcaccctgac
    56701 gagcctttgt catcggcttt aagaccgatt gtgtcatgtt aaatgctcct gtcagattga
    56761 ttttgagaac acgctcaaag tcctcctctg acatcttaag cattaattta tcattagtga
    56821 tgccagcatt gttaatcaaa atgtccacag agccaagctg ctcaatagcc tcatcaacca
    56881 ttcgcttagc atcagccccc tctgaaacat ctcctgagat cggcacaacc ttcacaccgt
    56941 aatccttaaa ggtctccacc agctcatcag aaatcgctga gcgaccattg agaacgatgt
    57001 tggcgcctag tcctgcaaat tgatgagcca ttgctagtcc aatgcctctt gttgaccctg
    57061 tgataaaaac gttttttcct ttaatttcca tagcttagca ttccctccta ttttcccaaa
    57121 tacaattgta ggcttggcat atcttcaaca ctgctgcata gcagcttttt gtcgattttt
    57181 ttaataaagc ctgttaaaac cctgccaggg ccaatctcaa caaactgggt gataccgtta
    57241 gccttcataa cctcgatact atcataaaaa cgaacaggct ccatgacctg acgcgccaat
    57301 aattctgcaa tccgatcctt ttccatgacc ttagcctctg tatttccaac cagtggcaga
    57361 tcaaagtcct gaaattgaat cttgctgagc tcctctgcca acctttgact agcaggcgct
    57421 aaaagtgctg tatggaaagg tcctgagaca ttcagcggaa ttaaacgctt cactcccttt
    57481 gcttttaaga tttcaagtgc cgcattgaca gcctcagctg tcccaccaat aacaatctgt
    57541 cctggcgtat tatagttagc aggtgacaca acaccaaccg aagaagcctc ttgacaagcc
    57601 tcctcaataa gcctagcctc tgtattcatc acagctacca tcttaccaga gccagcaggc
    57661 gctgcctcct ccataaagcg tccccttttt gcaactagct ctagggcagt ctcaaaactc
    57721 agaacacctg ccgcaactag agcagaatat tctccaagag aaagccccgc caccatatca
    57781 ggatgaaccc cataagaggt taagatacga taaatggaga ctgaagcggt taagattgct
    57841 ggctgcgtgt aggctgtctg gttcaaccga tcctggtcgg tatcaatgag cttgcgtaaa
    57901 tcatagccta aaagctgact agcctgatca aaggtgtcac gagcaatggc atattggtca
    57961 tacaaatctc ttgtcatgcc tagtgtctga gcaccctgac cagcaaataa aaaggctgtt
    58021 tttgtcatac ttctccttat ttatatcgtt tcgtttttgt catcagctgc aagagcttgc
    58081 cagcgcttag cttcttgact aatcactgct gctgcaccat agtagatatc ctttaggatg
    58141 gcttcacagc tttcttctgc tctaattaag cctgcaatct gccctgccat gacagagcca
    58201 ttgatcacat caccatcaat cacagcgttg cgcagagctc ctgctcccat ttcttcgatg
    58261 tcactagcag ccttacgatc tgctaaaaat tctttttcag ccttagcata agctgatgtt
    58321 agcttatttt tgatagagcg taccggatga ccaacaactt gagctgaaat gacagtatca
    58381 atgtccttag ccttcaaaat tttatcctta aagctttggt gagcattaga ttcctttgcc
    58441 acaacaaatc gagttccaac ctgaacagcc tcagcaccca gcataaaggc tgctgctgca
    58501 cctcgaccat ctgcaatccc acctgctgca ataactggaa tagaaacagc atctaccacc
    58561 tgcctaacca aggtcatcgt tgtcaattta ccgatatggc caccagcctc cattccttca
    58621 gcaataacag catcaacgcc taatttttcc atgcgcttag ccagggcaac gctaggaaca
    58681 actggaatca cgataatacc tgcctcatga aggcgctcca tgtatttccc tggatttcca
    58741 gcgccagtgg tcaccacctt gacaccttct tcgatcacca aatcgacaat gtcatctgca
    58801 aagggagata gcagcatgat attaacccca aagggcttat ctgtgatcgc tttgacacga
    58861 tcaatatttg ccttgaccac ctctttagga gcgtttcctc caccaatgat cccaagacca
    58921 ccagcattgg agacagcacc tgctagatca ccatcagcca cccaggccat acctccctga
    58981 aaaatgggat aatcaatatt aagtaattct gtaatacgtg ttttcataat aaccttctat
    59041 gcaaagaaat caggagaata atttgataat caaactatca taataagaag aaagagcgag
    59101 ttagagcctg aaagagggtc taatctcacc ctgatggttc gattattaca tatcaattga
    59161 ccaactaaag cagttcatta atcagcaggc tggttaatca gtattctcgc ttgtttgagc
    59221 tttattttgt tttttcttca acgtaggcaa caaggtcacc aactgtgttt aagccttctt
    59281 ctgtttcgat ttgaatgtca aaggcatctt caatttctga gatcacttgg aaaacatcaa
    59341 gtgagtcagc atctaaatca tcaaaggtag tttctaaggt tacttcctct gcgtccttgc
    59401 caagctcctc aacgataatt tcctgtactt tttcaaatac tgccatttta tgtctcctta
    59461 atataaatat ttattttata aatgtgctag gcacatgata taactagatt ttaacaatta
    59521 gactgcccca tgtcaaacct ccaccgaagc ccgacagtaa aatatgctgg ctgccgtcta
    59581 atttaagctg tccattttgg actgattcag atagcaaaat cggtatacta gctgcactgg
    59641 tattgccata gtgcatcata ttttccagaa atttctctct tggcatacca attttcttag
    59701 ccatcttatc taaaatacgc cgattggcct gatgtaaaag cagatagtct aactcctcct
    59761 tggccaagcc tgattgctca ataattgctg taatgctcct tgaaacatct ctaatcgcaa
    59821 agtcaaagat agcacgacca tccatctgaa gaaaggagtt gacctcctgt ccttgagaaa
    59881 atggtgagcg cagactgctc tgacctgatg tcaggctttg accttgcgca ccatcagtat
    59941 gtaaggcctc agctagaaaa tgctgctgct cgctggcctc taataaaacc ccaccagcac
    60001 catctccaaa taaaacagct gtgcttctat cctgccaatc aataatctta gacagggtct
    60061 ctgctccaat aaccaagcct ctttgataag cccctgatgc aatcaactta tccgccattg
    60121 ctaaggcaaa gacaaagcca ctgcaggccg ctgtcatatc aaaagcaaat gcattagtag
    60181 caccgatagc agcctgaacc tttgctgccg tcgatggcat gctagcatct gggctaatcg
    60241 tagcaacgat gataaaatca agtgcagtcg catcatatcc tgaccctgct aacaattgct
    60301 ctgctacccg aatggctaaa tcactggtca tctccacagt ggaaatgtga cgcttctcaa
    60361 tcccagtccg tgacgaaatc cattcgtggc tggtgtccat gatttgcgac agatcgtcat
    60421 tactaataac ctgcttaggc gtataatgag ctacctgact aatttttgaa aagaccatta
    60481 aaccaaatcc tccaaaaact gatgtaagtt ccccaagcca cgtaacaggg cttgcatttc
    60541 gtcctcattc atatcagcga tcacatgacc gaccatattt ttatggaatc ttgcatggag
    60601 acgatccaga agacgcccct ttttggtcag tgacaggtaa acaacccgtc tatccacgct
    60661 tgatcttgtt ctttcaatat agccctttag ctctagcttg tttaagctag tggtaaccgt
    60721 tcctaaggta accatgagct ctcttgcgat gtcacttggc gttacctgct gatattttcc
    60781 aataatctca attgtgtgca tctcctttag agaaacatca ttaaattgac ttgtttttaa
    60841 gctcatttcc tcaataacca aaattctgtt gaaaatatca actaaatatt gattaatctt
    60901 attatattcc aagtaaacac ctccctagct gtaaaatact ttgactatca aagtatatca
    60961 gacatcaaag tattttgcaa gcacataaga gctatttccc ccgaaaattt ggccgcctcc
    61021 tatctccata agccctgacg ccctctttaa agtcctcctt aaaggccaat tcctcttgaa
    61081 tagcaagctc tttttgggca taatcctccc aacctgcaaa aaagctttgc cataccaaag
    61141 atttcatgcc ggcgtaggaa tttgaagagc cacgcctcaa acgctttaac agctgactac
    61201 aggtcttatc aagcttatct gactcagcag ctcgatagac aaatccgtac tcaagccctt
    61261 tttctgctgt gaccccctca ccggtcatca ccagatgagt cgctctattt agaccaacgg
    61321 cacgtgttaa caagaaaaga ccaccagcat ctggcgctaa gccgacatta acaaaggcct
    61381 gaataaattt tgtctgggtg ctagcaatac aaaaatccac cgctaaggca atattaaagg
    61441 ccgcaccagc caccgcacca tcagcacaga ggataaccgg ctttggcaat tgcttgatag
    61501 caaaggaaat atcctgaacc agctcagcaa tcctaactag agactgaaca tcatctcttt
    61561 caacagcatt ttgcatctca accaagtcac caccgactga aaagaccttg ccctttgcct
    61621 taatcactaa aaagcgcaga gaggggttat ccttaaccaa cctaatagcc tccagaatct
    61681 cctgacaggc tggaatgtta aagccattag acacctctgg acgatttaag gttaaaatgg
    61741 ccagatcctc ttcaagctca aaaatgatat tttgaaacgt catatcactc ctcttttctg
    61801 acagcttatt tgattaccaa ataattttat gaccaaataa tttgacaatc aaattaatta
    61861 ctagactata gtacactaga atcagtcgtt atgcaagaaa aagattgtaa aaaatacatt
    61921 aaaattgact gcgcaattta aagcatgcag ccctaaaacc aagctcagac ctagcctcta
    61981 tacctctaat aaaagagcct aagacaaaag tgtcctagac tctgaaactt tggcatgtgc
    62041 tatgctcaac cattctatac aattgtgatc aatcgctcat agagtgtgta aacaagaccc
    62101 gcttaaatat cctctagagc gtctttgacc ttgtcaaaga aacctttttt ctttggagca
    62161 atcggctttt cgccactagc ctccgcaaaa gccttcaagg cctccttttg agcctcattg
    62221 agcttggtag gcgttacaat gtttacagtt acatgctggt ctccttggcc tccgcctcga
    62281 agcttaggag cccccttgcc cttcaagcga aataccttac cagtttgtgt tccagcggga
    62341 atagacatgg caacatcacc atggaccgtt gggatatcta ctgtatctcc caaagcagcc
    62401 tgaacaaatg aaatattcaa gctgtagtaa atagtagagc cattgcgctc aaactgttta
    62461 cttggaagca cgtttaaaat aacgaacaaa tcaccataag gtccaccatt aaagcctgct
    62521 tccccctgac cctgtaggcg gatttgttgg ccggtttcaa cacctgctgg gatttttact
    62581 gaaaccttat gaaccttctt ttcatgacca gttccatgac aggtatggca aggctctttg
    62641 atttcttgac cgctgccatg acagacatca caggtcacct gacgacgcat catgccaagt
    62701 ggggtctgcg tatcaacatt gataacccct gagccatgac atttacggca ggttgtagga
    62761 cttgttccag gcttagctcc tgagcctgca caggtgctac aggttgattc acgatgatag
    62821 ctgacctctt tttcggtacc aaaaacagct tcctcaaaag aaaggtttac cctatattga
    62881 aggtcatcgc cctgacgtgg agcattggga ttacgcatac caccaccgcc aaaaaagctt
    62941 gagaaaatat cctcaaagcc gccaaagcca ccaccatcga agccgccaaa accgcctgcg
    63001 ccaccaccaa agccaccgtt tgctccggct gccccgtatt gatcataggc tgcacgcttt
    63061 tgtgaatcgc ttagggtttc ataggcttcc tgtacgtcct tatatttttg ctcagctccc
    63121 ggctctttat tgatgtctgg gtggtatttc ttagacatct tacggtaagc tcgtttaata
    63181 tcatcggccg aagcgtcctt tgagacccca agacgatcat agtattccgt attattcatt
    63241 tattctttcc ttcattgaca aaaacagacg gagcgaggcg ccccgcctat ttgattttta
    63301 tttatttagc cttgctatgc tattttctag caattagggg aggggactat cgcctcagtt
    63361 tctagcttta ctgagcgacc ttagctcctc acagcttatt tttcagtgaa ctcaccatct
    63421 acaacatcat cgccactgtt tgttgagcct gtatctgctg caccttctgc accagcctgg
    63481 gcttgttgtg ctgcggctgc ttgctcgtac attttaacag caagggcttg tgctttttca
    63541 ttaagcgctt caagcttagc tttcatatca tcaaggtcgc ctgactcttg agccttctta
    63601 agctcatcaa gagctgtttg agcagcatca cgctctgtgt caaagccttt gccttcagtt
    63661 tctttaatag tcttttcagt tgcaaagata gcctggtcaa cttcattttt aaggtcaacc
    63721 tcttccttac gttttgcatc ggcttcagca ttggcttcag cgtctttcat catgcgttca
    63781 atttcttctt cagaaagacc atcgttagat ttgatgacaa tatgttgttc tttttgagta
    63841 cctaggtctt ttgccttaac agaaacaata ccgtttttgt cgatgtcaaa ggttacttcg
    63901 atttgtggga taccacgagg ggctgcagga atgtctgtca attggaagcg tccaagtgtt
    63961 ttgttatctg ctgccattgg gcgttcaccc tgaagcacgt ggatatcaac agctggctgg
    64021 ttgtctgctg cagttgagaa gacctgtgat ttagaggttg gaattgttgt gttgcggtca
    64081 ataagctttg taaagacgcc acccattgtt tcgataccaa gtgacaatgg tgtcacgtca
    64141 agaagaacaa cgtctttaac atcaccagtg atcacaccac cttggatagc agcacccatc
    64201 gctacaactt catcagggtt cactgatttg tttggctctt tgccagtttc agccttaaca
    64261 gcttcaacca cagctgggat acgagttgaa ccaccaacaa ggataacctc atcgatttct
    64321 gacaagctca agcctgcatc agacagcgct tggcgaacag gaaccttcgt acgctctact
    64381 aaatcacgag tcaggtcatc aaattttgca cgagacaggc tcatctctaa gtgaagcgga
    64441 ccagcagcgc cagcagtgat gaatggcaat gaaatttgag tttgagtgac acctgaaagg
    64501 tcttttttag ctttttcagc agcgtccttc aagcgttgaa gagccatttt atcttgtgat
    64561 aggtcaatac cgttttcttt cttgaattct gctactaaga aatcaatgat tttttggtca
    64621 aagtcgtcac caccgagctt gttgtcacca gcagttgcaa gcacatcaaa gacaccatca
    64681 cccaattcaa ggatagacac gtcaaaggta ccaccaccaa ggtcaaagac taagatcttt
    64741 tcttctttat ctgtcttgtc aagaccgtaa gcaagagctg ctgcagttgg ttcgttgacg
    64801 atacgttcta cctcaagccc agcaatctta cctgcgtcct tagtagcttg acgttgtgca
    64861 tcgttgaagt aggcaggaac tgtgataaca gcctttgtta ccttttcacc aaggtagtcc
    64921 tctgcatagc ctttaaggta ttgaagaatc attgctgaga tttcttgtgg tgtgtattct
    64981 ttaccattag cagcaacctt ttcagaggtt cccatctttg atttgattga gataacagtg
    65041 tcagggtttg tcactgcttg acgcttggca gcgtcaccga caatgatttc accgttttta
    65101 aatgacacta ctgaaggggt tgtgcggttg ccttctgggt tggcaatgat tttgctttct
    65161 gttccttcaa gaactgctac tgctgagttt gttgttccta agtcaatacc gataatttta
    65221 gacataatat tttttcctct tttatatatt tatgatactc ctcttatgtg gcacggacgc
    65281 tagcagcttc ctatggaatc tcatagctga aatttgagcc taaagtctca aattttccga
    65341 gtcataaaac actagtgttt tatgactttt gccacggcga agagtatcgg taatgctcac
    65401 ttcgttcgct tttgctagcg caaaaagcag caatcttatt tcttattttc atagtttacc
    65461 gtcatttcgg acatgattca ttttattgat tagctatcat cacgggataa ttgcgacgtg
    65521 agatagcaaa atcgatacca ttttgctatc gagctagtaa ggagtctagg caagccgcca
    65581 cagcggttgc cgtctaatga cgagccattt caatggccat cattagtgac tagttgtaca
    65641 caaccaccat cgctggtctt agtaagcgct catgaagctt atagcctttt tggaaaacct
    65701 gagcgatact atctgctggg tggtcatcat ctgctggtag ggtttggact gccatgtgca
    65761 gattgtggtc aaaggcttcc acaggaacct cttcaatacc ttcttcttta agggcttgaa
    65821 caaggctttc ttgcaccatt tctaggcctt ttttgacatc atctgtcaga ccctcaacag
    65881 ccaaagcacg ctccaagtta tctaagcttg gaaggatttt tttagctaaa tcctgtgaac
    65941 gatagcgctg caagctttgg cgttcttcat tcgcacgacg ctgaatattt tgcatttctg
    66001 cgtgagctct gaggtattta ttttcaaaat cttctgctcg ctggagagcc aactctagct
    66061 cagatggttc ctcggctgct tcatcagcaa taagctcagc tgattgatca gcttcttcaa
    66121 ctggctctac tgcttcctca gcagcctcat caagaatgtc ctcttgatcc ttgagctctt
    66181 cttttggttt tttagacaag gtgtctaccc ctttcttaca ttttcttaaa tcatattaag
    66241 gccttagtga acctcataat ggttgctgtt taagtaacgg taataatctc ttagcttcac
    66301 agccagtagc tgaccaatca cattaatcaa gctaacacta cgacgataat ccatatcaac
    66361 tggcccaatt aagcttaaga ggccaaatcc tctgtatgga attaaaaact tgtaggtcag
    66421 caaggtcacg tttgctaggg ctggctcact gctgtcagca acctgaaccg ttgccatctc
    66481 ttcctctgat agactctgtc tgatagatag ggctaagcgc tgctcctcat caagaaactg
    66541 ataggtcgca agaccagcat agtcaagggc agcaaccttg ccagagacaa aaatcgtttc
    66601 tcgaaaaagc ccgacaaaga tataatcaaa caaatccaaa acattgtctg tcaccgtaaa
    66661 atacttctga acaatctgag ggatttcggt tcgcagcttg taatgaacag tcataacatc
    66721 tttgccaagt aagcgatcag caacaatgcc cttaagcacc agcaaatcac gattcataaa
    66781 attcttagga atggcaaact gtacggtcaa cggcttggac tcatctaagc tcaaaactgc
    66841 caaggcatca tgactagata gctgaacaat atcaaagcct gtcagccttt gccttgcagg
    66901 ctcaacatct aaaatcgccg ccgtatagcc ggtcgtatcc gatagcatct ggctggctct
    66961 tagcaaaacg tcctccagct taaaggcctc aaaatcaaag gccttgacca gctgataaag
    67021 gtcctgctca tcaatgctgc caagattaag agaatgctct acaaaatatt taaagcctgc
    67081 cgcacttggc atgcgcccac ttgatgtgtg agccttctcc agcaatccta gtttttcaag
    67141 ctttgccatg tcatttctaa tagtggcact actagaagca ataagtgact gcaaagcctt
    67201 agagccaact ggttcatggg tctgtgtaaa taaatctaca ataagattca aaatattaga
    67261 ttgtctctct gtgatcacaa accaatcact ccctttctgt tagcactcta tacatcggac
    67321 tgctaattta taattctatt atatcctttt aaactagcat gtcaagaaaa aaactcaaaa
    67381 aattagcact ctttttttag agtgctaatt tttataaaac attgacagtg ttgcctttga
    67441 cattatgctt gaaagaagta atagagagcc acttactacc tctcagactg gtattggctt
    67501 ctcccgactc gctagctaaa aggagcgcta agctgtaagg gggattagct taactgcctg
    67561 aagccttaag gcctaacaat caagccttta gtagagcagg ataaatcagg ctgcgtgctc
    67621 acagctccta ctcttaaggc ttacaccttc aagctgatag aaagttgcaa tacctactaa
    67681 agcaaatacc tgagcttacc ggttgtttcg gtgtcttttt catctcctca atcatcatag
    67741 cttgtcaaac ctcttgcttc aatcagctgc acaagccttt gggcatagcc cttatcatca
    67801 gaatagcgat aggtctgcag acttttagca ggttttttat accctttttc ggttgctagg
    67861 ctttggtaaa gctttttctc ctcgcctgtg ccttgactaa gccatgataa gtaagctctg
    67921 atagagtcct ctctgtcccg atagatagca taggctgtct tgtgctttga ggctgcttgc
    67981 ttcttgaggc taatggaagc ctgccctgga gctggctgca gtgaaaaaag gttgtggtat
    68041 ttggccgcca acagggttct gccataattg gtttctaaaa taatctgacc aatcaaaata
    68101 gaaggacgaa tgccatagtt tttggccaat ggcttgacct ccttagcaac caactggata
    68161 aattgcctct ctgtataggg aacagacatc tcctgactgg ccgatgtgcc tttggcattg
    68221 aacagcaagg gaccaatcaa agccaccata atgaacacta aaaacactag aaaataggaa
    68281 aatttaagtc gttttctcat tttttctcct tcaatcgtgt taggtattct tctaggctga
    68341 ggctatgagc ggtaatgtat agggcagagg ctttaccaac atagcgataa tgccagtcct
    68401 catactcaat ccctgtgcta gtctgcttcc cttttggata gcgcaaaata aaaccaaatt
    68461 gtggagctat tttttgaatc tcctgtgcca ccttaggatc actagcgttt aagttatcta
    68521 ctgtgctcat atcaatggct agaccagtct gatgttcact agtgcctgct ggctgggcat
    68581 atttccgaac caaggcttca gctgcctctt gggtcaggct aggatcattt gccagctctt
    68641 gggcaatata agactgataa agctcttctt gctggacaac cgaacgataa ccagcaatca
    68701 agtgctcctg aggttcaatc gtctgcgccg ctgctagaaa atcagccgtc tcctgctcaa
    68761 tgcgcttatc aataggaatc ccattaatct caaccaactc aggactcatt tcctcttgag
    68821 ggtgatcgcg attgacaagg accagctgcc agtccgtagt tgataccttt ggcagatcag
    68881 tagtcttttt agcctgctta gctgcctttg gggcaggtac tgtttgatta gccttggggc
    68941 ctacagcctg tttttcaggc ttgataaaga ggtaaacccc tgataaaaac aacaggacga
    69001 ccaaggcctg taaaaggact cttatagtgt tattcttcat ctcttattga ctcaattatc
    69061 tcacgaccac gatagcggta gctcatatct ccaatcgttt tgatggtaaa ctgcccattc
    69121 tcatattcca caacagtgac gcttccattg tcaatgtatt gcttttccct atctgggtca
    69181 attagccaca taaaggttcc aatggtcatg ccatgactaa ccacgatagc attgccacct
    69241 cctgcatttt caacagcaag cgcgatagcc tcaaagccct catagatacg cttgctcaat
    69301 acctcccagg gctctgccca gttagcagta tcaacctcga caatactctc tgctaattct
    69361 gaataaggca catcacgcag attgtcacga ttttcaaagg cctttgttct aggtaaaaca
    69421 cctaaaaaca gctcggaatc ataagcccca tctagactac caaagcacca ctcacgaatc
    69481 cgcttatctc tagtgtaggg taaaaactca ttttcagact ttcgtagaat aatctccatt
    69541 gtctgcatgg tacgacctga atcactcgaa aaagcagcct tgaatggaat accagcagcc
    69601 ttcaaaccaa gtcccaattc acgaatccct tcttctcctg cctttgtcaa gggggtatca
    69661 ctccaaccct gtgcacgacc aatggtgttg aacatcgtct tgccatgtct gacaatgtat
    69721 aatcttgttt ttgtcataat gaacctccaa agtctctctg ctattatagc attaaaagaa
    69781 aacacttgca aaaccatgca agtgctagcc gttaattctt aaagctatgg ataggagctg
    69841 gtatctgccc accacgagca ataaagtcag ccgatgaatg cggattaaca gccataaccg
    69901 gagctgtccc taaaagacca ccaaaagcaa tcatatcacc ctccttaccc tttggaataa
    69961 tacgaacagc tgttgtcttt tgattaatca ccccgatagc tgcctcatca gcaatcatgg
    70021 ctgcaatggt ttcagacggt gtctcctctg ggatcgcaat catatccaaa ccaaccgagc
    70081 aaatggcagt catggcttct agcttttcaa gattaagcga gcctccctgc actgctgcaa
    70141 tcatgccctc gtcctctgat acagggataa aggcacctga caacccaccc actcggttgc
    70201 aagccatgac accacccttt ttgactgcgt cattaagtaa agctagggca gctgtcgtgc
    70261 catgtgtgcc aactatttca agtcccatct cctctaagac acgtgccaca gagtcaccaa
    70321 ctgctggagt gggagctagc gacagatcca caacaccaaa gcccacacct agccgctcac
    70381 ttgccatctg tcccactagc tgaccgatac gcgtgatttt aaaggccgtt tttttgacgg
    70441 tctcggctag aacgtcaaag ctttcaccac gaaccttttc caaggctctt ttgaccacac
    70501 caggtcctga aacaccaacg ttaatcaccg tatccgcctc accgacacca tgaaaggctc
    70561 ctgccataaa aggattgtcc tcaacagcat tagcaaagac tactagcttt gctgccccta
    70621 tctcagaggc tttggcggtt tccttgatga tacgccccat gtctgcaact gctgtcatat
    70681 taataccaga ccttgttgat ccaacattga ccgaagcgca gaccttctgt gtttgagcca
    70741 aagcctgagg aatagactca atcaaaatct tatcaccctt ttgatagcct ttttgcacaa
    70801 gagctgaaaa gccaccgata aagtcaactc cgatatcaca ggcagcctga tccagagctt
    70861 ttgcaagcga caggtagtct tctgcgtctg ttgccgcccc aataagggct atcggagtta
    70921 cagagacgcg cttattaaca atgggaatac ctagttctgc tgcaatgtca tcaccaaccg
    70981 ccacaagatt agctgccttt gtcgtaatct tttggtaaat cttagcggca gctctatcaa
    71041 tatccgaatc aatacaatcc agcaaggaaa ttcccatcgt aatggtacga atatcaaaat
    71101 gctgctcctc aatcatctca actgtttcac gaacctgtct aatatccata gtcatcaagc
    71161 tccttatatg ttatgcatag catcaaaaat cgctgcgctt tgaatattaa tcgtcacctg
    71221 caattgcttt ccataagcct gaagcacctc acgcagatga gcaaaatcct gcttttcact
    71281 gcttgagaca atggccatca tggtaaaata atcatctaaa acggtctgtg aaatgtcatc
    71341 aatatttaac cctaatgcag caatttgtcc tgaaacacct gcgacaatcc cttgattgtc
    71401 cttaccaaca actgtaatga tagctttcat ggcacacctc ctcaatatgt gttatatttt
    71461 atcacaaaca aaaagagaaa gctatcagag acaagaggtc tggtagcccc ttgcaaaaat
    71521 agaacaatgg gtaccagaaa aaagagtttg ttatccaatt gataccgttt attaatattt
    71581 agactttata atataatagc agctaataaa agataagacg tttgaagctg ccaaaaaagc
    71641 tgggtctaag gaagcccagc ttttttgtag gttaattaag ggatagcaga agattagtcg
    71701 ggattgtaag aatagccgta tcctctctta ccacctctat cagctagacc atctaaatag
    71761 ccatttccat aattatcatt atacccttga ctatagtcat tatattcctt tggactagac
    71821 tcatcaaacc gcttaggata atctcctttg tgctttttgc caccatatcc atcctcatag
    71881 ccaactcggt aaccatcacg acgaccatga ttgtaggggt gttcgtcttt aagttttggt
    71941 gattcatcat tttctccgct taagccttta ccgtctaaat cttcctttgg cttattctct
    72001 ccatctaatc cttttaaagg atttttacga ttatttcctt ctaaattcgg agttgatggg
    72061 ggaccggctt cacctcgttc accttgctct ggttccttct gattctcacc attcaagcct
    72121 ggaagcgaag gacggccttg attattacca ctcaaccctg aaagtggggg accagcctca
    72181 cctcgttcac cttgctccgg ttccttctga ttttcaccat tcaagccttt ttctggcagc
    72241 ttgggactat tgccctgagg ctttggttga ggctgcgggc tagaattatc cttacctaga
    72301 tctaagtgct gtggctttcc ttgtggctga tggtgatgac ctgaaccaga gctgttacct
    72361 cctctcagcc ccagtggctg ggaaggccct tgattaggaa tagcctgagg ctctgaggcc
    72421 tgtccactac tatttccttg gctgttcaca ctgagagact gaggttgatt cccatgatga
    72481 cctgagctct ttgctgtcgg ctgggacggg ctagtagcct gatgctgatg attagtaggc
    72541 tgatctgaag gcttaggctg caagttatcc tttttcggtg gccgactgac cattgaatct
    72601 gatgagctct tgtgcgactt atcgtcatct ccaatcgagc tgactggctg ctcctttggc
    72661 ctcgcttgat gggatgagcc accaagactt cctaataaac ctccaaagac aagtgcagct
    72721 cccagcagca agctggtcac cactgcaccg gcaaatagcc attgtttttt ggacttccat
    72781 gtgcgaaaac gtccttctgt ttttctcata cttttttaac tctctccata ttttttggta
    72841 aaaataccaa gaaatagtat atatagtcaa gactttatca tatttctttt aaatttttat
    72901 catctgatat attcgattgt ttttacaaat ctgataacca aaaaatcctc gtatcatact
    72961 gatacaagga tttttatata tttgaacgtc acaagtactc ctggcttatt gttttttgcc
    73021 aaagagcgct gaagcaacaa ttatcacaat agctgctcct agaattgaag ggaaaacagc
    73081 catgcctgcc agctgaatac cccagtcgcc aaacagcttt tgaccaactg cagagcctat
    73141 caaaccagca gcagtcattg tgaaacagcc catcgaatgg cttttttctg ttatcctacc
    73201 tgcaaccatg ccgataatag ctccaacaat taatgaccaa accatcgcaa atctccttta
    73261 tgttttgtct tattatacca tacccttgcc ttatatcagt cagatgatgg tggtcgcttg
    73321 atattaagag caagctgctt ttttctctta gtaagcaata agtctctcag cgatatcaca
    73381 agcactgcta ttaaaatcaa ggccattcct aacagatcaa tagggtgaaa aatctctttc
    73441 atcaggataa tcgcaaagca gacagaggca accggctcaa ttgaagccag caaggtagcc
    73501 ttgatcggtc caatgattga agcccccttt agaaaaaagg tgtaggcaaa aattgtccca
    73561 ataccgataa tgccaaacag ggcccgtaga ttcccataag tcattgccaa tgggtactgc
    73621 catgctcttg tcaggatcgg aaaaatcact cctcccatca gcatggcaag accaacaatc
    73681 agcaagctcc cccagtcggc aatcagctta gcaggcttga tgacacagta agcataggtc
    73741 accgctgcaa aaagccccca gaaaagtcca ataggattga ttgccagatg ggaaagatca
    73801 ccatgacagg ccatgataac cgttcctagg atcgctaggc aaatagcaca gctctctccc
    73861 acagccggca ggcgtcttga tttgaacgat aggtagacca gcaccaaaat gggggaaagg
    73921 tattgcagga ctgtggctgt accagcatta gagtaacgaa tagcaagcag ataggcatat
    73981 tgattaagtg tgagaccaaa tagactgtaa atcaacagct ctcttaaaag ccttttgtcc
    74041 ttgagtaagc tgatgacagc ctctctttgc cgcacataag ccatagctga cagcacaagc
    74101 cctgaaataa tgagccttag tgaggtcaag gcattgatgc cgaccccatg agcaattaaa
    74161 tattgccctg acacccctga gagaccccag gcgattccgg ctagtaaaat catggtactg
    74221 ccttttccat ttcttgacat attatcttcc tctttttaat ccatgccatg ataaggccac
    74281 tcataatacc ttgatagctc tagcctagac ttcaccaagc ctgcttaaca gtcattaaca
    74341 acagaccgat aagctacctc ttacagcttc ggatagcgag gtattatcac agaattgtcc
    74401 taaagagcct accatcataa agagcctgaa aactctgttt cagactcaat gccagtcata
    74461 acgactcctt aatccagcaa tttttgcaat tcttgggcta acaattgctg agctatctgt
    74521 gggttggctt gcccctttgt ggccttcatc agaaaaccag taaaggcctt gtcagcattg
    74581 cgcttgcctg atttgaaatc tgccacagca gcctcattgt cagcaaacac ctgatgaatg
    74641 attggaatca agacagctgg gtctgaaatt tgaaccaagc cggccttttc cacataagca
    74701 cgcgctgagc cgccatgctt tgccaaatga acaaaaacct tcttggcgat ttttgatgaa
    74761 atcgtgccat cagtgatgat cgcaatcatt tccacgagat tttctggggt caaggcaatc
    74821 tgatcaatcg tcttgccctc agcatttaag aattgagcca tctcaccctg aagccaatta
    74881 gacacctgct taggatcacc accaagtgcc acagcctgct caaagaaatc agacaaagcc
    74941 tttgttgctg tcagctgacc tgcatcatag gctgacaagc caagagcatt aatgtagcta
    75001 gctcgcctgt ctgccggaaa tcttggaagc tctgcacgca tatcctcaat ccatgcgtca
    75061 tcaatctcaa acaatggcaa atctggctct gggaaatagc ggtagtctgc tgctccctcc
    75121 ttgacacgca tgagaatcgt tcccttactt gcctcgtcat aacgacgtgt ctcctgacga
    75181 ataacaccgc cagagcgtag gattttggct tgacgctcca cctcaaactc aagcccctta
    75241 cgcacattgc taaatgagtt caggtttttc aattctgttt ttgtaccaaa ggcctcttgt
    75301 ccgtatggtc gcaaggagat attggcgtcc acacgcatgg acccctcttc catcttgaca
    75361 tcagaaatac cagtatactg aatgatttcc tttagggcag tcaggtaagc ataggcctcc
    75421 tctggagagc gcatgtcagc ctctgagacg atctcaatca agggcactcc ctgacgattg
    75481 aggtcaacat aggaataacc atctgtacca tgcgtatttt tgccggcatc ctcttctagg
    75541 tgagcacgct caatacggat tttcttggtt gagccgtcct caagagtaat atcaatccag
    75601 ccattgtagc caatcggctc atcaaactgt gaaatctgat aggccttggg attgtctggg
    75661 tagaaataat tcttacggtc aaagtgcatg tgctgatgaa tagacatgtt aagagcaagt
    75721 gctgctttga ttcccgcatc aatgactccc ttgttcatca ctggaaggac acctgggaaa
    75781 gaccagtcaa tcacattagt gctggcattt ggatcctctc caaaatgagc tgatgaaggt
    75841 gagaaaatct tagaattggt attcaactcc acatggacct caagtccaat aatggtttca
    75901 aaattcatta cctgtcacct ccaaaaatca taggctgctg cttgtggtag tcagtagtcg
    75961 cttcaaaggc taccgctacc tgatagatga cctcttcgct atattttgga ccgatcaatt
    76021 gaagcccaac aggcaagcca tctgcaaagc ctgctggaat agagattgca ggcaagcccg
    76081 ctagattcac cggaatggtc aaaagatcag ccaaatacat ggcaacagga tcatgattca
    76141 acgtatcaag ctcaaaggct gctgttggtg ctgttggtcc taaaatcaag tcataatcag
    76201 caaaaacctt ctcaaagtct tgaatgatca gcgtccgaac ctgacctgcc tttttgaaat
    76261 aagcatcgta atagcctgat gataagctaa aggtaccaag catgatacga cgcttaacct
    76321 catcaccaaa gccctgacta cgcgtcttga catagatgtc ctcaaggctc ttggcatcag
    76381 cagcacgaaa gccatagcga ataccatcaa agcgctgtag gtttgatgag gcctcagatg
    76441 aagcgatgat ataatagaca gccaccccat acttgctatg tggcagactg acctcctcaa
    76501 tgatagctcc tagcttctca aaatgcttag cagcagccaa aaccgtctcc ttaatcttag
    76561 gatcaatgcc ttcgccaagg tattccttag gtagtgcaat cttcatgccc ttgatgtctt
    76621 gaccgatctt aattgtgtag tcagcgatct gtacaggtgc tgaggttgag tccttgcggt
    76681 cactccctgc aatgaccgat agcagctggg cattttctct taccgttggc gcaaaaggcc
    76741 ctatctgatc tagcgagctg ccaaaggcaa tcaagccata gcgagaaaca gccccatagg
    76801 tcggcttaag cccaacaaca ccattaaagg ctgctggctg acgaatagag ccgccagtgt
    76861 ctgagccaag agataagcga acctgacctg aagctactgc tgttgcagag ccacctgatg
    76921 aaccaccagg aaccctgcta tgatcccaag cgtttttggt tttcttgaaa taagacgttt
    76981 ctgttgagcc acccatagca aactcgtcca tattggtctt accaataaca atcatatcct
    77041 tgtcgtaggc attagctacc gctgtcgcat caaaaatcgg ctcataatta taaagcatct
    77101 tagaagcagc agttgtcaga atccccttgg ttgagatatt gtccttgaca gctagtggta
    77161 ttcctgacat cacattgtca ggatcaatcc ccttagcatc aagtgcagca gcctgcttta
    77221 aagcagcctc gcaagcaatg gtaatgaaag aacccacagc ctcctcacgc gccttgatat
    77281 cctcaagggt tgcctttgtt agctcaactg cagaaatgtc ctttgcaaca agaagctcat
    77341 gtaattcttc tatagtatga tgattaaaag acattaggca tctcctccgt catcaagaat
    77401 agctggtacc ttgatgaaat gattttcttt ttcaggaaca ttttgaaaca ggagcttgcg
    77461 atccactcca gcctcagcga tatcagctcg catgatattt ttcttgtctg ccattgtggt
    77521 ggtaatggca acacctgtcg tatccacttc atttagcaat tcaaccatgt caacgatttt
    77581 tgataatgtt gtcgcaaact cagttgtttc actttctgaa aaggatagct ttgatagggc
    77641 cgcaacgtgg cgaacctctt cttcagaaat tttcatgaat tctcctatcc aaggtaaagc
    77701 agaccatcat cagccacaag gccttgctgt ttcaaacgct tgataatagc ctgaataacc
    77761 caattttaca tagtcttaac cattatatca taattagctt tatttaccat agcggactgc
    77821 tgggatttca cgtcaaatgc atgtggcaac tgacgttttc tgataacgtt tttcataagc
    77881 tcaacctgct tttttcaaga acagccaggc tataactaaa ctgcatttga gcaattgatg
    77941 aggttaaaag ggcaatgtgg ctagagcata gctacctgca ttttattcac gtgtatgcgt
    78001 agctgggatt agcgaaaaac ttaataacaa aaagcctcct agccaagacc aaaagatctc
    78061 actaagaagc ccttaagatc agcgctgagc caagcagcag ctaatactgc cttacttgat
    78121 tagcctatcc cagctgatcg aacgatcgcc taagaaagcc gatcaagaag ctttgctcct
    78181 aggacagtcc tacagtggtt cagcgcccac tggtgatttt ctgttgaatt gctcgccact
    78241 gctgatgtga taatctcaag cttgtagccc aatttatagg catcaatcgc tgtatgaagg
    78301 acacaaatat ccgtcagcac acctgtcaag accagcgtcg tgacgccacg ctcacgaaga
    78361 cgaatatcca aatcagtccc cgaaaaggca gaataatgcc gcttatccag ccaaaagacc
    78421 cgctgatctt gctggtatct ggtatatacg gtcatcaaag gaccatacag gtcccgaccc
    78481 cttgtcccga taatattatg cggcggaaac aaggctgcct ccggatgaaa gctatctccc
    78541 tcctcgtggg catcaatcgc aaaaaagata tagtagccgg cctcaaaggc agcctcaaca
    78601 acgctagcca tcgcctctga aatcacctga gcaggtgctc ctgccgtcag gctaccatca
    78661 tcagctacaa agtcattcgt gtaatcaata gaaatcaagg ccttcacagc ttatccctcc
    78721 ccaaaaagct tatgctctct tagctgcatg acagcaagcc ataagaacta agcctgcttt
    78781 taatattcag tatgattaga cacttatagt ttaccactaa acacgacagc tgtcaagaca
    78841 gcggattgat ttatacacga taaaggcgaa aaacagttat ttctgaacta tagtatagat
    78901 ttaagtagac actttcaacg tttttctata tgaaaataag atatattcct gaaatagctg
    78961 aacattgaaa tacagaaagc cttattttct tgctaaaaat ctttcatgca tctgtcatgt
    79021 tcatctcatg ctgaatcaca gcgaaaatac aaaaaatacc cctcaaaagc cagccaatgc
    79081 tagaaccttt gaggggacgc tataataatg tgtgaagtcc tccacagctg ctaagaaact
    79141 ccgataagcc gtcataaaga ccaagtctag cccttaccaa gcagggctct ggctaatgaa
    79201 tggctgctct ataagcagca agactttgat catagctaac actttcacta cctgctctga
    79261 ctaatcacag ctagcaaagc taaaggcaag ccttgggctt agcagacgat cgcatctgag
    79321 ctattaaaat tcctttagct tgtcaaagat gccttcgtta atcaccttga gataagtgcc
    79381 tttcattcct agagagcgac tctcaatgat acctgcactc tctagctttc taagggcatt
    79441 cacgatgaca gatcgtgtga ttccaatacg atctgcaatc actgaagcgg tcaggcgtcc
    79501 ttcattgcca tctagctcac taaggatagc tgcaacagcc ttcatttcag agtaagatag
    79561 agtgttgatt gccatattaa caactgtctg cttacgaatg gtttcttcta ggttttctgt
    79621 ttgaagattt aacagctgaa taccgaccac agtgcttgag atttcaacta aaacaaggtc
    79681 atcatcactg aattcattgt cgttacgcca gatgatcaag gtacctaagc gcatgccgcc
    79741 accatagata ggggcaatcg tggttaaacc atcaggatag atatcctttg actcaatagg
    79801 aaaaatcgtt agttcatttt ccacagaaag gtttgcttca gtgtcataaa cacgactagc
    79861 tgccttgaca taagcatctg ggaactgtct tgtttcaaaa aattcctcga cgcggtctgt
    79921 gttggtcttg tacttcatcg catagccaag taagctgccg ccaccattga tgatacaagc
    79981 attacaatca ataatatctg ctaagcgtga agccatagtg ttatagggga gttctgtttc
    80041 caagctgtct acagaacgtt gcaaaataga agtaatctta cgggtttttt ctaataaatt
    80101 tggcattttt tcttttcctt ttaattattt gcgttacaat tatatcaaag gaccctagct
    80161 tttgcaagga attatcagaa aattggctat tatacctaca attcggatga ggccagagcc
    80221 ttattttgct gaaaaacaaa aaggatctcg cgatccaatt tttgtatgag aatcatatta
    80281 gcgcttgtat tgcttgagaa catgcgtgat cttttcttgc acgtcagcta gctcttctac
    80341 tgttggcaga tagaccacgc gaaaatgatc aggctccttc cagttgaagc cacgcccatg
    80401 taccagcatg accttttctt gcttcaaaag ctgtaggaca aattcctcgt cgtcatcaat
    80461 gcggtacata tttcgatcaa ttttcggaaa caaatagagg cctgccttag gctttacagc
    80521 tgataggcct ggaatggcat taatggcctg gtaaatgaag ttacgttgct caaagatgcg
    80581 accacccgga agcaagagct catcaacaga ctgacgtcct cctaaggagg tctgcaccac
    80641 ctgctgcgct aagacattgg agcacaagcg catgtttgcc agcatgttca agccttcaat
    80701 gtaacctctg acatgtcttt tagggcctga caagaccatc cagcccactc gaaagccggc
    80761 aatacggtgt gattttgaca gcccattcat tgacacgcaa aaaacatcag gtgcaaggct
    80821 ggcaattgcg atatgctccc caccgtccat gaccaaacga tcataaatct catctgcaaa
    80881 aatgataagc tgatgctctc tggcaattgc aacaatctcc tctaagacct ctcgagggta
    80941 gagagcacct gttgggttat tgggattgat aatgacgata gcttttgtgc gctcagtgat
    81001 cttggctttt atgtcagcaa tatcaggata ccattcagcc tcttcatcac acaggtaatg
    81061 caccgcatgc ccaccaccta ggctgacaca ggctgtccaa aggggatagt caggcattgg
    81121 caccagcacc tcatcaccat tatcgagcaa ggcttgaaga gacatcgaaa tcagctctga
    81181 gacaccattt cccaaataaa tatcatcaat gtcaacatca ggaaagccct ttagctgaca
    81241 atattgcatg atggccttac gagctgaaaa aatccccttg ctatcagaat agccctcgct
    81301 ggagcgagca ttgagaatca aatcacgaat aacctcatct ggagcctcaa agccaaaggc
    81361 tgctgggtta cctgtattta atcgaaggat cttttcacca ttagctatca tacgattagc
    81421 ctcgtccagg actggacctc gaatatcgta ggctacgtgt tctaattttg atgatttttc
    81481 aattattttc atagtctcat tacctcgtaa cccatattat aaaccaaaac aattaaaata
    81541 gaaagcactt ttctatgagc ttaaagaatg ccaaaagctc aaccaaagct ctaagcaagc
    81601 taagcagcag ctattaataa ggctatctaa gctagcttct agctcaaggt atcctcacct
    81661 cagggaatag ctgggctatt tggtgaacaa tagctcagaa aatcattaaa acgttttcaa
    81721 tttctcctca aaaaaggtat aatagctata gagataaagt tcaaaggagg ataaaccgat
    81781 gtcacaaaca tatgaacgta tcatggtcgc tattgatggc tctcatggct ccgaattagc
    81841 ctttcacaag ggggttaatg tcgctttgcg taatggtgct gccttgattt tgacccatgt
    81901 tgttgataca cgtgcgctgc aaagcgttgc aacctttgat agctacattt atgacaagtt
    81961 ggagcaggaa gctaaagagg tcttggggga ttttgaaaaa caagcacgcg aggcagggct
    82021 gactgaggtc aagcaggtga ttgaatttgg caatcccaaa acgctattag cgcacgatat
    82081 ccctgacaaa gaagaggttg atttgattat ggttggggca actgggctta acacctttga
    82141 gcggttgctg attggatcat catctgaata tatccttcgt catgccaagg ttgacctatt
    82201 agtggttcga gagcatgaca aaaccctgta gcaagacgaa ttctctcagc tgtcagaagc
    82261 atttgcagcc taagtgaagt aaccatacct agcccttagc ctcagctcac aaggctacta
    82321 aaggactact gctctcatat actaattacc actagctaga cttaagggcc cttttattga
    82381 gggtgtctag tctacatcaa aaagcaccct gagctaataa gtgaagtgac cccaagtgtt
    82441 aggccaaatg cttaacagct aggagatcaa ctcacagctc aaggtgcttt ttaatgcctc
    82501 taaaataaag acagccttat ttttccaagc gctgcaatga tttttgaagc tgcttgtcca
    82561 actctttttt gatggctgac tctggtgcat agcgctcctg ccagtcatct ggcttttgaa
    82621 ttttatgcgt tatgggatca aaatgcgctt tcccatcagg gaaaattttc cccatattgg
    82681 cttcatggac ggtctcaaaa atgggctgag ggtccactcc catcaataca aatgagccat
    82741 aggtaaaata aagcagatct gtcaaagcat caacctgccc aaccaggggt gactctgggt
    82801 gctccttggc ctgcaccttc ttagctgcct tatcaagggc agcatggagg tctatcaaag
    82861 cctgagaaaa gcgatgctta tccccttgac tggctgcata aagaaattcc acaagttcct
    82921 ctaccttaaa atctgctcga tagccagcct cctttaagga atagcctctt ggtgtttcaa
    82981 tcgtgtctcc gtccatcagg cggtggaaat ccttgacctt gttgaaatta tcatcgcgac
    83041 ttttaaagct tttttccaca tcaaaatgaa tcaagccata atgcgccagc gccttagaga
    83101 taccatcatt gttatttgaa gctgttgtaa agtgagcacc gcttttaacc actgcctcag
    83161 catttcccat cgcaacacca acaccaacgc ctgagagcat ttctaagtca ttatcagagt
    83221 cgccaaaggc catgacctct gagagctcaa agccaaacat ctcgcccaag cgttcaatgc
    83281 ccttgatttt agactgcccg ctagaaatca aatctaagga ataagggctg cttctggtta
    83341 ccttgatatg cgggaatctt tccttgattt tttgggtgtc atcaacagaa gcaaccaaga
    83401 caatctgata aatcggctct ctcataatgg taacaagatt gctgaagctt tgcggcttaa
    83461 agcgtctgat gaggttttta aagctgccct caaccgtctt gaccagactc cttggcacaa
    83521 tactgctaac catctgacca aatggactgg ttcccatatc aatgatccga gacccagcaa
    83581 gacctgaagc tgttcctaag gagatctcgc gctttttatc gctagcatag cgaatgattt
    83641 tataaatggt tgactttggc agctggttct gatacaagac cttgtctcgt gtcaaaatgt
    83701 attgaccatt gtaggtcact gcaaaatcca agccaaaatt ttctaaaaag ggctgcacaa
    83761 aagcaggtcc acgaccagtt gccagcccaa ccataatacc ttgttttttt aattgctgaa
    83821 tagccctttg cgtcgttttt tgaacatttt ttcgatcatt aagcagggtt ccatcaatgt
    83881 cgaaaaagac tgcttttatt gtcaaatcct tctgttctct cttctatttg tgataaaata
    83941 aattatatca taaattgaaa gaagtatgag tatcaaatga aggaaatcct cgtcttacat
    84001 accggcggca ccatttcaat gcaggctgat gaagcaggca aggtgagccc aaatcaaaac
    84061 aatccaatga atcaggttgg ccttagcctg gagcatatcc acctaactgt tgtggatttt
    84121 ttaaatctgc caagcccgca catcacccct caccacatgc tcaagatgta tcattacatt
    84181 caacaaaggg ctagtcagtt tgatgcagtg gtcatcacac atggtacaga taccttagaa
    84241 gagactgctt attttctaga cacaatggtg ctgcctgtag agttgcctat tgttatcaca
    84301 ggtgctatgc gctcggccaa cgagattgga agcgatggta tctataacta cctaacagcg
    84361 cttagggtag ccagccatga gaaagccaag ggcaaggggg tgctggttgt gatgaatgat
    84421 gaaattcatg ccgctaagta tgtcaccaaa acgcatacca ccaatgtttc gacctttcaa
    84481 acaccgactc atggcccttt gggagtcgtc atgaaggacg atttactgtt ctttaagact
    84541 gctgagccaa gggttcgctt tgagcttcgt catatttctg gcacagttcc gattatcaag
    84601 gcctatgctg gtatgggaga tggaagtatt ttaagccttt tgacacctga taggattcag
    84661 ggactagtga ttgaggccct cggcgctgga aatgttcctc ccctagcagt atctgagctc
    84721 gaaaaattaa tcgcctctgg gattcctgtt gtcttggtct cgcgctgctt caatggcata
    84781 gcagagccag tttatgctta tcgcggaggt ggtgccagct taaaaagggc tggtgttatg
    84841 tttgtcaagg agctaaatgc ccctaaggcc aggttaaaat tgctcatcgc cctcaacgct
    84901 gggcttacag gtcaagagct gaaggattat atcgaaggct aagctctcct ataatcacag
    84961 gctactactc ctcatctata gcacaaaaag cacgactcgg tcagctaaga acctcttgtc
    85021 gtgtttttat attagctctg tccagcaagt cagcctcaca tctaatcaaa ctgatcagcg
    85081 acacgaagat tagccaaaat cggagcccat ctagggtcca gctgccaatc cttagctgca
    85141 acaatctcag cagcgactcg tcttgcctcc tctaggatat gataatcctc tacaatatca
    85201 gctgttttga actctggcaa acctgattga cgggtcccaa aaatctctcc tgagccacgc
    85261 agcttgaggt cagcctctgc cagcacaaag ccatcattag tcgttgtcat gatggtcata
    85321 cgctccttgc ctgagtctgt cttaggatct gccaccaaaa tagcatagga ttgcttgctg
    85381 cctcgcccaa cacgaccacg caactgatgc aattggctaa ggccaaagcg gtcagcattc
    85441 atgatcagca tgatggtggc atttggcaca ttgacaccaa cctcaataac ggttgttgac
    85501 accaagacat caatctcctt agccttaaag cgctgcatga tcatctcctt gtcgtctgcc
    85561 ttcattttgc catgcatcaa ggcaacacta gctgaagctt taaaataatc cttcagctca
    85621 gcctctaaag ctaccgcatt tttcaaatct agagtttcag attcttcgat caaaggagag
    85681 ataacatagg cctgtgtccc cttagcaagc tcggtcttta cccaggccag cacactatct
    85741 aattgccgat gcttgaccca gcgagtgatg attggctttc gccctgccgg taattcatca
    85801 ataatggaaa cgtccatctc accataggca gttatggcta gggttctagg tatgggagta
    85861 gctgtcatca tcaaaacatc tggattgttg cctttttcgc gaaacaagcg acgctgattg
    85921 accccaaaac ggtgctgttc atcagtaatc accagcccta gcttatgata ggtcactgcg
    85981 tcttggatca aggcatgcgt cccaacaatc atatccacag acccatcagc aatagccgat
    86041 aaagctgctc ttttttcagc tgctttcata cccgatgtca acagggcaat agacaaatct
    86101 ggaaagagct gacaaagact atcgtaatgc tgctcagcta aaatctcagt tggcaccatg
    86161 agtgccgatt gaaatcccgc tgtttgggca gcatacatgg caaggcttgc gatcactgtc
    86221 ttgccagagc cgacatcccc ctgcaacaga cggttcatat gagcccctga ggtcatatct
    86281 gctaagattt cctccaggct tctttgttga gctctggtca gtgaaaaggg caaagcagca
    86341 atcttttttg ccactgcctg ctgatgaaaa ggaatcgcta acccattgcc ctctgccttg
    86401 ttagcaagct ttaaaacctg cagattcatc tgaaaataga aaaattcttc aaattttata
    86461 cggcgcaggg cctgcttata atcctccata tgtttaggaa aatgcatggc ataaacagca
    86521 gcttgtctcg gcagcaggcg gtatttctga atcaagggct ctggtaaatt ttcttccagc
    86581 tgagctaagg caccgctatc aaaggctgat ctgatcgcct taatcagggt gggttgactg
    86641 atcccctgcg ccacatgata aactggctgc aaatcatctt ctaaggtcat gagcaatttc
    86701 atacctgtca aggctgcttt tttttgatcc cacctaccaa agatagccac ttcctgatcc
    86761 aagacgattt tctcaagcag ataaggctga ttgaaaaagc tgacactaat cacaagctcc
    86821 ccctgcttca atttaaagct caggcgatta cgcttgaacc catagtattg aacgcttggt
    86881 ggagtcacaa ctctacctgt aaggacagcc ttttcaccat ctaaaagctc taaggctgac
    86941 ttgcttttaa aatcctcata gcgaaaagga taatagagta gcaagtcctt gatctgataa
    87001 atgcctaatt tttgaaattt ctcagctgac tttggaccaa gacccttcaa attagcaatc
    87061 gaactcttta acagcatctc aacctcgctt tctttttcat tattatatca aaaatcaaga
    87121 gcctctccaa aaaggaagag gctcgttttc ttactgtaga tgccttgagg tattagccga
    87181 tcctaacaca cccttagtgc ggccgctagg acggcctaac taaaagatga agagtggcat
    87241 ataaacaata cagcactgct tgctaggcca agatatgccc tagaattgtg atagctactg
    87301 ctagcttgtc aagagttggc ggcttgtgat tggtcaatcg cagctagtgg ttatcagatc
    87361 aagcaggaac acctgctgct ccaaggagcg ataaagccat caccaataca gcaccagacc
    87421 gcttgagcaa ggctaggcct ttacctgctc aactgataga tactatcaca ggcttgatcc
    87481 agtaattcct cgtcatgaga gatgacaatc actacctttt tttgctgctt tagctccttt
    87541 aaaagactaa ccagagcctg catttgcagc agatctaagc cactgcttgg ctcatcaaga
    87601 atgacaatct ccttgtcaga caagaggctg gcagcaatca tcaccctttg ctgctcacca
    87661 cctgataggc tggcagggtg cttgtctaga agctgagaaa gcccaagcct attcaccaaa
    87721 tcatcagtag cctgatgtct atgatgacct agattaagct ccttttctac cgtctccgaa
    87781 aatagctgta gcccaacgtc ctgcaacact aggcttgtga ttgaaagcct gtccttagca
    87841 ggcagggtga cacccagata gctgatcttg gcctcttttg cttcaaaaat acctgccaga
    87901 tataaagcca actgcgattt tcccaaaccg ttagctccgg taatgccagt gatttgccct
    87961 gcaccaaagc tgagctgatt gaggtgatac aaaaccctgc tgcctgcctt gacctctagc
    88021 tgcttgattt gcaaggcatg ctctggatca taatgctcaa aaacagtttt tgcccgcaaa
    88081 gccttagtca cagcagtcaa ctcacatcgt cttagtccta gctcctcacg ttcctgatct
    88141 ggcaaagcta gcagatcctt ggggcttaat acgcgctcta gcctaccagc tgaaaaatag
    88201 taaaaatggt ctgccaaatc cagcaaataa tgcaagcggt gctcagcgac aataatggtt
    88261 ttgccagcag ccttaagctg ctttaaataa gccttgaccg ctgctacact agcatggtcc
    88321 aaattggctg ttggctcatc aaaaaccatg atagctgtcc cttgcatgat agctgctgca
    88381 atagccaccc gctgcttttg accaccagat agcttaagca tatctgcttc tagtaagtcc
    88441 ttgatgtcaa aatcagctgc caaggtatcc agcctctcaa ggataagagc tggctctaag
    88501 ccttgatttt cacaaggaaa aacaagctca tgcttgacct cacgatagaa aaattggctg
    88561 gctgggtttt gaaagacaga ggaaacctgc cttgacagca cttcaacact agcctgacca
    88621 gcctgatgag acagtacttt cagacttcct tgtaattgtc ctgaaaaata gtctggaatc
    88681 aagccattga gcagcttaag aaaggttgac ttgcctgagc ctgactgacc acaaagcacg
    88741 ataaattgac ctgcctctat ctgacaatcc ctgagctcac aggcagtctg cctacgattg
    88801 gtataggaaa actgcagctg ctttgccttg atcactggag aaccatgtag gctatcgtca
    88861 caaatatcca aatctgtacc ccccaatcct tccatgatag atgtgatacg aagcactcac
    88921 ttgctccctt tttgattgct agcccttttg ttaggctagc aatggttaag tcctgactac
    88981 ttctcagcaa tgacatcaac agcggtacca agagatactc catataccgc cttggctgtc
    89041 tgacaatagc ccagctgtcc aagaaaatgc ccctgatttt cagagattgc cgaataatct
    89101 ttccttcttg cctgatctta ggtaaaaaac gcagcatgac agcaagagtc aacagacaaa
    89161 cctctggcac atgccatttt cgcagcccat gcacaagctc gtaggcagtc gttgtcttga
    89221 caaaaatcaa agcagcaagc acagatgggt aaagcaattg accagcaaca gctgcaaagc
    89281 tcagcagcct aaacagatag gctggcagca catgaagcgg caatacagac aaagcaagca
    89341 gtaaggcata gagcagtgtc ataccgattg ccagacgccc ttgaccaagc caaaacaaaa
    89401 tgccaagcaa aacacctata atcatcgtcc ccagccagcc atcaatccga aaaaagaagc
    89461 aggcattggc tagaattaac aggagcaatt ttgtgcgaac atcaagcctc ataaaagcat
    89521 tcctgactta gcaaaatgct ttttcagcag gtattgacca aaaaggccac ctactaaggc
    89581 acaaagaagg acaacaccaa caaaccagct aacatttgca acggtaaagt catacatgat
    89641 acggttaaca tatgccatgt ccttaccacg cgctaaaaga ctctggatat aggcgtcctt
    89701 caacagccac attaaaataa taggaccact gttaacaaag gcaaaaacaa gataagacaa
    89761 gagattcact agtctagatt gatattttcc taaaagggct atgccatctg ccaaacagcc
    89821 aaaaagaata gctggtagca ttgaagcaaa aaaatgacct gtcaaaaaga aaaagcttcc
    89881 cataataatt cctactaggc ttatcggtcc aaaggtctgc agcttagcga ttaatagcat
    89941 ataaactggc ccgccaagca aggccgcaaa ggctggcgca tagagcatat tgcctgagcg
    90001 atcaaacaga atgctcagca tggctcctag ccccacacaa acgaaataga gggcggcaaa
    90061 ggcgcctgtt gtcatgatat ctttaatggt taaccctttc attgtttacc tccttcaaaa
    90121 aaccatttct cacacaaaat agctggtctg cacaggccaa ggtggatggc cgatgtgaaa
    90181 tcaaaaagac cattccccgg caatgctttt taatcaaatc aataaagatg gcttcattca
    90241 gcgaatctaa gtttgatgtt ggctcatcaa aaatatagca atccgcccgc ttcaatagag
    90301 cccgcatcaa ttccaagcgc tgggcttcac cagctgaaaa gtctgctgat cctctcacta
    90361 gggtatctag cccctcatca caggctagga tacgctcctt catgccacag gcctcagcaa
    90421 gttccatgat atcatcatct gaaatgtcct tacgaccaag tgtgatattg tcacgaagtg
    90481 tttgctgaaa tagctgcgca ttctgtggga cataggcaaa gttagcctgt agggaagcag
    90541 catttagcgt ttgactgtca acctcactca ggaaaatatg accagcttgc caattgtacc
    90601 atttcataat gatcttcatc agagttgact tcccagagcc tgactctccc tgaataccga
    90661 taatgccttt cttttcaaaa gcgacggata agtggtggta aatagtctcc tgatgcttgg
    90721 gataagcaaa ggtcagatcc tcaacagcaa tccttgttac cgaggaaata cgctgatctc
    90781 ccttatctac taacgcttct tcatctaaaa gctgaaagac attcctagca gcattcatgg
    90841 cacgcttgaa gccaagcggc aaacgcccca attctaaaaa gggtgcaaag gaggctgtaa
    90901 aggcaacaaa agccagcaac ccaccagcaa acgtcaccgt ctgctgactc agctcaaaaa
    90961 gagtaacata agcaaaggtc aaaatagaca agccaagagc caaaaaggtt atcgccattt
    91021 gtaaaaattg agcctgtgcc acctgacgat caagcgcatt aacatgcttg ctctgattgg
    91081 ataagagctt aaagcgcttc tcaatgcttt gaaattgcag caaatcctta acagatctga
    91141 gactctctaa aaagcttgac acataagccc tgcgcccttc attttgcttt ttgagcagtg
    91201 attgaaggac gtttgaaaaa tacactggaa taataacagc caaaagcaca taggtcacaa
    91261 tagcccccaa ggctaacttc cagctaacct gccaaaggta ataggccatc aagctagctg
    91321 aaataaacgc cgtacaaata ggggcaagcg tgtgggcaaa aaagacctcc aaggcctcaa
    91381 tatcctcgcc aatcatcttt aacaggtgcc cgctgtcctg actgtctaag cgtgccggcg
    91441 agagtgctct tagcttttta aagacaatcc tgcgaaaggc tgccaggcta tgaaaggcaa
    91501 caaaatgccc aaaataatgc tctccataac gaacaagccc ccttagcagt gccatagcaa
    91561 caaatagata aagccattta aaggtaatag catgaccagc catcacctct aagcccagat
    91621 aggctaagct ggtaggaatg ccaacggtaa gcacaaagcc cagcactgca aacatcaccg
    91681 ccagagctat ccaagccagc aaatgcttca tcatagcaag caatcgtaaa actagccggt
    91741 aggtgctgta atcactctta accataaaga tttgcctcca attctacttg tgtatcaact
    91801 aattgacgat aggccaaatg atggcggtaa agctctcttg ggctagccaa gctagcagac
    91861 tgctcagggc ttaaaaagag cacctgatca gcctgcttca aatatttcat cttatgagtg
    91921 atgacaatta caatggcctg tttagccaat tgctgaagca gtctgtgaat agcagcttca
    91981 ttctcagcat caagacttga ggtagcctca tcaaaaatat aacaggaacg ctggctcaat
    92041 aaggccctag cacaaatcac ctgctgtctt tgccctgcag ataagtgaca gccattctca
    92101 cctacaatgg tatcaatccc atcaggtagc cagtaaataa agctcaaaat gccatgctca
    92161 tcaatccagc taagcagctc ctttctagtc agctgagctg ccatagcaag gttctcataa
    92221 atactcatat taagcagcgt tgactggtca gaaacgtaga gtatttcctg attgatggcc
    92281 tgtttagaag ccagatcaat cgtcacatca ccaaggaata tctgaccgct atctgcctga
    92341 tagcgcttca acaggagctg tgcaagacta gtcttaccct gtcctgaaac acctgcaaca
    92401 gctgttagct cacccttttt gatagtcatc gtgatgtctc ttagcaaagc cttttcccca
    92461 tgtgaaaagg acaaatcttg aatatcaata cgatcaaagg ccggtaaggc aactcccttg
    92521 tcttggtcaa cagcctcaac actatctaaa aagccaaaga tttgatctgc cattttagta
    92581 ttcatcatga ctaggtgcat gccatagccc tgctccctaa taggggcaaa aaattccgtt
    92641 gcaatcagga taaaaaagag aaagtcaaaa aaggatatac caccagctga cagagcctga
    92701 accgctaaaa agccagataa gccaatgcca agatacatga cagcgtccat atagccaacc
    92761 gcttgcagct gaaagcccaa gagctgcatg gtagccttac gaaaggcctc tgccttattg
    92821 acaaagcttt cctcatacct ttcatctgcc tgataggaat aaagggtatt tagccccttg
    92881 agatcgtcca taaatagatt gccaacgtcc atataggttg accagtaatg gttcatgatc
    92941 cttttagagc gtttttgcat agcaacaatg gatatgggaa tcaagggcaa agacaagata
    93001 aagaccaagc cccctatagg atagatcaaa aaaacaagca gtaagaccgt tgtgcaatta
    93061 aaagctgtta gcattgcaag cgataggtaa taggaataat aggtatccaa gctatcaatc
    93121 ccttgtgagg caaccgttaa cacatcagcc tctgttgact gctgatcaaa ttgcccgtcc
    93181 atagcaataa aggcatcaaa aaaggattgc ttgagcgagt cacgcgcaaa ttgcgaagct
    93241 aggccctgca gctgctttgc aatcatcgcc aagccaaagc caacagcatt taaaatcaaa
    93301 aggataacaa gcagccttgt caattgcagg gcttgacctg ctaaaaaggc tgtgaattgc
    93361 ttagcaatta agtaaaagct cattaaacgc atcaaaaatt gcagccaaga taaaaaggcc
    93421 gacacataaa gcaaaaaacg cttaggagca atacgctcct ttaaacgcct taaaagcatt
    93481 tttttctttg cgcgtgatat tttttcagtt gtatcgttca tataatcgtc gccttattcc
    93541 tatctatcat tcatttttta tttgtctcat aaagtggtaa gaacaaatcg cctatcctgc
    93601 ttttcaataa agggcaagct caccccaaaa accgcctcca caaaagcctg atcaagaacc
    93661 tcctgtggac tgccttgggc atagatggca cctttttgca gcccaagcac acaatccgaa
    93721 acagccaagg cctgattaat atcatgtaac accatgataa tggtcattcc tagctcctga
    93781 ttgatttttt tgatgagggc taaaatgtcc agctggtact taatatcaag ataagtggtt
    93841 ggctcatcaa gcactaagac acctgttttt tgggcaagcg ccatagcaat ccagaccctt
    93901 tgcttttcac caccagatag ctcctgcatt tccctaaagg ccaattccct tagattagtc
    93961 acctctaagg cccaagcaac aatgtcatcg tcctcttgac ttgatccctt aaaaaaacgc
    94021 cgatgggctt ggcttgccac agccaccaaa tcacccacca gaagatctgc taccgcctga
    94081 ttatcctgat gcacaacggc tactttttgg gcaaactgct taagactaat agagctaata
    94141 gcttgtccct ctaagaaaat ttgcccagac ttaacgggga tatttttagt cagcagacct
    94201 agtagggttg atttgccaca gccgtttgcc cccatgattg tcgttatctt gccttttgga
    94261 atggtaaagc tcagcctatc taaaataggc ctatcacgat aagtaaagga caaatcctct
    94321 acacgaatca agccttgctc atgactcata tcacgtcaga cctccttaac agataaataa
    94381 aataaggtcc cccgacaatg ctcatgataa cagctgggct aatctccaag ggataacaca
    94441 actgccttcc taaggtatct gccagcaaaa agacaaaggc gccaagcagg gcagaaaaag
    94501 gaatgagata gctatgctta ctgccaacta aaaggcggcc aatatgcggc acaatcaggc
    94561 ctaaaaatga caccacaccc acaatcgagg tggaaacagc agctagtaag accgcaacca
    94621 acgagattcc taagcgcagg taattactat caatgcctaa attacgaatc aagccatcgt
    94681 ttagcagcag tagatcacac tgccttgcta ggcctatcgc aagcagcagg ccaagcactg
    94741 tataaggcca cagcacacca acatctgccc aggttttttg actaatattt cctgacaaca
    94801 gcgcattgac aaagggattg ctggtttttg aaaaatcagt aatcgcacga gacaagccta
    94861 aaaacaaggc gttgatagct attcctgtca aaatgatgcg tatcggctgc aagcccttct
    94921 tccaggacaa ggtataaatc atcaaaaaag aaacacagcc tcccacaaat gataacaaag
    94981 gaccataaaa caagagctgc ggcaaaagca ggctagataa caagaccata aagctagccc
    95041 cactgcaaac cccaataatc gccggatctg aaataggatt ttttaaaatc gcctgaaaca
    95101 agaccccaga tgttgctatc cccgccccag ccaataaagc aatcacaatc cttggaaagc
    95161 gtaaatcgta aataagggct acctctgaat catatgctac aaataagcca ttaaagatcc
    95221 tctgataaga aacagataag cccccaacag agaccgcata tagcattaaa ccaaacagca
    95281 gcatgagcaa tagaaccata tagaccagtc tagtggtcct ttttcttgct gctgtgactt
    95341 gatcagaata ttgactacct tgctgcatct tacttgactt cctttgctcc ataaaagatt
    95401 tgtgacagat ggttcaaagc ctctttgtag ttaaacttag cactcatgcc aaaaagggta
    95461 ttgtctaaat cataaacctg ctgagacttg acagcttcaa aatgcttcca aatatcattt
    95521 tcagcaaatt ccttatcaaa catgtcctta accttgtctg gaatggcgtg ggcagtacgc
    95581 aaaatcagct caggctgctg ctgaagcatg tcttctggat tggcagacaa aaattccttg
    95641 tcctcagagt gataaacatt ctcaccacca gccagctcaa gcagattacc aacataggat
    95701 ttatttgtag caatcagata gctgccagga agccccatca aaataagaac cctaggcttt
    95761 ttttgccctt tatgcttttt cttaaaggcc cggtaaaact cctcataatc agcccgcaag
    95821 cgcttagctt cctttttgcg atcaaacaag tcccccaaat catcaatcga ctggtacatg
    95881 ccttcaaggc tagttaaatt caaaaagcca tattccgtat ccaattgctg gtatttaggc
    95941 tctaaatcat tttgcagaga attgggactg agtatccacg ttggctttag agaagcaata
    96001 acctccatat caggattcat cggcagaccg atccttttga cagcatcgta acgctttggc
    96061 aattggtata gcttactgtc acagacccca accaaatcta ggcttagccg atcacaaata
    96121 tcaacaacag ccacagaggt ggcaacaatt ctctccttat cagccttttt ctctgcccta
    96181 gggtgctgat ccacacaagc agatagcacc aaggacaaaa cagctaatcc aataagctta
    96241 atgactttct tcattgtttt ttctcttttt ctttataaac aagaccaagg ctcctgacaa
    96301 caaaagagct gttggtacat agtaaaccag aactggcaat ggattattta ctggcttttg
    96361 ggacgactct tgcttacttt tatctagcga agtgctcaaa ccaactgcct gacccttctt
    96421 agagggattt gactgttttt tgggactgct tgattgacca actggccttg ctgagggatt
    96481 aggagctgac ttggcgtctt ttgagtccgg tttactagga gctttcttct catctgcctt
    96541 tgcaggagct gtcaccgcat gatccgtctt ggcttctcct gctgcaaagc tagctaccat
    96601 atctccactg tagccttctt gtagctcaga tggtgacagg taaaagacaa cctctctgcc
    96661 cataggctct acgtacatgc tgcctctaac aaccgtattg acatcaggca aagcaatcgc
    96721 aatatccttt gttgtgccat tggtatcagt gccaaccttg gtgacactgt aggctgccgc
    96781 ctgaaaagcc cctgtaccac ccggctgaac ccaaaattgg tagttacctg aaaaatcagc
    96841 tagactcatg cgaaaggtca gatacaaatc cccagccgag gttacctcta gcataccatt
    96901 gctataaact gttccttcca ccataccttg gccaatctca aaagcgtgct caccaccgct
    96961 atcttcaatt tgccctgaaa ccgggtgacg ataatctcgc ctaatcacac aggaataaag
    97021 ctcaccctta tcagcatagg ccttacctcc tatagctgct aggcaaacca gcaataccac
    97081 caagccaccc attaattttt tgaataatct ctttatcata tgttcctcat taatgatctt
    97141 catttcctta cgacaatcaa ataaggcata gatttagacg caggccaaga cctactctta
    97201 tttgactatt ataacacctc aaatacgaaa agcataccca ttcctcactt accaagggta
    97261 agcttaagaa atcattagaa acaggcatgc ctttacgtat cgttgataag ccttgatgac
    97321 tacaagcgat taaaccaagc tcttagtgca tcaaacagac tctctactga cttaaaataa
    97381 ttttttccta ccaagaatga gaccaactgc tatgacaata aagcttgcta gaccgataat
    97441 gatatggccg cgatgatcag ctttcatctg ctcctgacta tgtttagcag ccttagattt
    97501 agctttggct ctagtcttag cagcctgctt agaggccttg cctgtaccag ccttagacgc
    97561 cttatgtgaa gaaatcaggc tcttaagctt atctgtaccg gtcttagcgt cctccttggc
    97621 attactgctt ggagcagctg acttcttagt caaaagattg gtcaaattag gaatagcagg
    97681 acttgtatga ccaccaatga tacctgtgtg aggctgcaag agctcaccta tggtaccatg
    97741 tccctgattg tcctctgagt gtggcaattg tgccttatcc tttgtcaggc tttgaagatc
    97801 caacttcata aagactgtct ggaagcctgt tcccttagag atagcgtcca taattggcac
    97861 aaagacgcga agaggtacca agccatcctt tttagcctga tcaatcagcc taaatctcaa
    97921 cacctgtggg taattgctgc cataagcgtc tgacaggggc ttgcctgtga catctgtaaa
    97981 gtaggacaca acctctgctt tttctgtctt accaaccggt ctgccagtca aatccctttg
    98041 gtagccatca acaaagtagc tcaactctcc gagataccct gtcaggttac cgatcttcat
    98101 gcccttaaag gtcacctcta ggctatagac acccttattc acaatcaatt tgacgcggtg
    98161 gtcaatagcc tgatgagaca ttgattctga ctgcaaatca tttttaagca tgcttgcctt
    98221 gatgtagtag acaccatctt caagcttatt aatatccaag cccttagact ggtcactacc
    98281 tgcaagctga tcctccttga cctcaacatc attagaggtc agataaatat gctcacgctt
    98341 cttagcaaat tccttggtga taagagcctt acgaacacga taaacacctg ctccctttag
    98401 gtcaaaggag ccttgaagct catcttgtgg atcgttattc aagcgtctct catcaacggt
    98461 gacatattga ccggttgatg tttttttctg caattgcacc acaatatccc agtcagcata
    98521 acgctcattt aataaggcaa tgatgtctga cgagcttgcc ttaaggcgtt tattgtaatc
    98581 ctcaacagag ctaatttctg cttcggtgct tgagagtgtc tgctgctccc aataatacaa
    98641 atcaagcagg ctaaaccctt ggtgataggt catcgcttga tgatttaaag tcgcagatag
    98701 attagcaaat tgcttttgtg ggtttagctt atttgttccc atgatctgtc taagcttatc
    98761 actaacgcca cttaggcagt taaacttaag atcaagatcc aatgccttta gatctgcaaa
    98821 atcagcttcg ctaatattcg ttaaaaggtt attatagaca ttaagctttg atagctgctt
    98881 attagccttg aaggctccct gtgggatttt agttagctca tttgatgcca agtcaacggt
    98941 taataagttt ggcatatgac taaagtcaat attagcaata tctaaaacct ggtttcgatt
    99001 ggcaacgata taagaaagct tagttagctt actcaaggag cttggcaggc tgcccaactg
    99061 gttttcagaa acatcaaaga agtttagatt atcaagtgaa gctagagcat tttctgaaaa
    99121 ttcagtaatg atattttcag ccaaggccaa ggaggtcaag cgagatagac cattaaagac
    99181 accatctcga atcacgctga ttctattttt tgacagatct agctgatcca gctgaccaag
    99241 atttctaaat agtccttcct ccagatttgg catatagttg cttgagagat agagctcttt
    99301 tagctggctg ttatgagcaa aggtatcctt atctagggtt gtaatcacat tgctgcgaag
    99361 atttaagaac cttagattgg tcatttgact gaaggtttcc tttggaatgc ttgcaatctg
    99421 attgccctct aagtgcagct cagtaatatg cttagcatgc tttaagagtg aaatatctgt
    99481 caaatcatag tggtctaggc gcagctcacc ttcaatcttc gcaatttcct caggtgacat
    99541 tttgccatca ccgttaaggt ccttaccaag cttaaccaaa accttttcaa gacgctcaga
    99601 gccgacccct ttttccttgt cgtcaatctc agcctgatag cctgtccagc ccttacttgc
    99661 tgtagcgcta aaggtcatgt ccaacttggt gtatttgtca tagtgatgta ggtcgctttc
    99721 ctgaccaccc atagctgata ctagcacagc acccttgtga agcttgtcca gctcctcaat
    99781 cggtagggta aattcactct aatgtagtta ttgttaatat cgcgttcacc aacctgagtg
    99841 cggacagagg ttggatactg ccctttactc tcaatggaaa agtcaatcaa aaattgccct
    99901 agagctgtat tgagcaatga aatctccatc ttgccatctt ctttgacgac cagcttggcc
    99961 ttcttatcaa atgctccctg cagcattgag gcttcctctg tattttcctt attggcctta
   100021 aaggttaagg tataggttcc tgcctttaga tccgtaacag ccagatcagt tccctgatag
   100081 gacttgatac tatccatcaa aagctcatag gtctccttga gcaatttttc attgtcaatc
   100141 tgacgatagg actccttgat cacctgaagc ttgctagaca agtccttgac ctgttcttta
   100201 ttggcctcgc tagcaatgat acgctcagct tccttgatcg cgctttccag cttagtaaaa
   100261 tcaagtccct gcggtgcttc ctgctgggat ccttgtctct gcttttgctt agcagaaaca
   100321 aaggtgtatt gctcccctga ctttttcact gtaatgatga catcttcaaa gctttgtgag
   100381 gaaatgacaa ccttgttttc tccctccttg aaagctgtcg tcccaagatg aagccccttc
   100441 aggtcagaca catagccagg cttgtccttt actgaatcat agaccaaatc cttatagtcc
   100501 tggtcattga ccttgatctt tgtgatttga tgagctaatt ccttaatttg cttggtgctg
   100561 gaatagcgat caatttccgg aaaaagaagc tctccttctg ttgtctctag tttggtgata
   100621 aatgataggg tcgctaagcc atcatggcta gttaccttag caggcttttc tgtcttagca
   100681 gcagcttgct gcggtgaagc agtagtatca tctgaaggct tggcagaaac aaaggtaaca
   100741 tcatttcctt tcttgtcaaa gaccacaaga atgcctccgt tagtcttatt gacgatgcgc
   100801 agctgatgct gtccttctgt gatgttctta gcgtttacct tgattccttg gtaattgatg
   100861 tcatagctat agtcaccctc cagctttttg tcatactctt taccatcaat gagaattttc
   100921 tcgatatttt tataatagag cttcccctct gacttgtccg catagggacc gatctcctcg
   100981 aacaataaaa tattatcctt aagcttgaca gtcgtcacaa gacttgaaga gacttgagta
   101041 gcctctgagc gaaccgtctg ggcagactgg gcaagagcca gcgttgataa agcaagaatg
   101101 gcgcacttat tgatactttt cattatttcg aaccttctaa aaatgttatt agccatttaa
   101161 ttattttatt aatctcactt aatttattat gttgtcaagc ctttgtcaag attgaatttg
   101221 agattttttt cacaataaag caaagaaaaa aacagccctg caacagagct ggattttttc
   101281 ttacaaaaat tctgtacttc tcgcctttaa agcaagaaga ttacttatga ttttccaaca
   101341 acataagtca attggttggc ctgctcagca gtaaaggtgc ggtatgaaat ctgacctaag
   101401 ccaagacaat ttgactctga aatcaggatg gagccgtcct ttctgacatc ctcaacaata
   101461 gagacgtgcc cataaagacc gtcagcaccc gcttgacctg gagcaaagga aaccgcatag
   101521 cctacctttg gctccttaga aatactgtag ccagacttaa atctccagtc accaccattt
   101581 cccataaagg aatcaaactg atagcctagc tccttagcgc gattataaac ataccaggta
   101641 cattgtcccc aagcatagct tgacgcctga tagcttaaaa tatcatagct cttagacagc
   101701 ttgtagcctg taggaacaac agcaaagctt gaagaggatt gaattttcag ctcagccgga
   101761 atctctggcg tgcctccatg ctgatcaatc caagcatcta atttttccat gatctcagcg
   101821 cgacgcttgc caatgccatt ggtatctgtg aagtaaagac caccatcact agcaaagttc
   101881 aactgctttt tggcaaattt atcagccttt tgatcctgct gctcaaaatt aaggttgcta
   101941 tttttgataa tcgtctcctg tgtcagctta acaatagcaa gctcatcatt aaactgattt
   102001 ggctttttcg aatcaaggtc aaaaagcgca tagccaaaca tgttagagcc tagtaaggtt
   102061 gcatttccct tggttcctag ctcactttct gtcattgcaa tggctacaat cgcccgcaca
   102121 tctagcccac tctttttttc ccattgcagc aaggcagcac cgttaattcg cttctcatca
   102181 tacttgatct tggtagactt taaaaagcta tcaagctgct ctgccttgat cccatagcgc
   102241 ctagacaaga ggttatgggt ataagcactc tgaccactcc aatgcgtcac ataagcagca
   102301 taggtattta cagaaggcag ggccagagtc aaggacaaat caactgtagg agcagcagga
   102361 acaatattca gtgccggctg agatgcctgt gtagcaactt caggggctgg ctgagggcta
   102421 gctgctggac tagtaggtgt cgactgtcca gtagaaccag aagctgatcc agagctagct
   102481 gtattgcttg atgaccccgt tgctccaggt tctccactgt tgggagtagt ctcagtggtt
   102541 gatgaggagt tgtcagtagc tgaggtagca gctgctgtcg aagtggactc accagtctgg
   102601 gcgattgcag cctcattagc agtagctgga acctggctgg cttcagctcc tgtatcctct
   102661 gccaatactc ttgcggtctc taaatgaggt accagaagag tcatcagcat tatcattctt
   102721 aataatttat tttttctcat ttagtattca atcacttctt tctgctctat tctaacctac
   102781 attataacat tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg
   102841 ataaaggtaa gggcc
//
LOCUS       DARYUW010000002        63011 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYUW010000002 DARYUW010000000
VERSION     DARYUW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63011
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            16..744
                     /locus_tag="TVW11_000097"
     CDS             16..744
                     /locus_tag="TVW11_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1364249.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            756..1931
                     /locus_tag="TVW11_000098"
     CDS             756..1931
                     /locus_tag="TVW11_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1364250.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            1941..2936
                     /gene="lacD"
                     /locus_tag="TVW11_000099"
     CDS             1941..2936
                     /gene="lacD"
                     /locus_tag="TVW11_000099"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1364251.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(2978..3697)
                     /locus_tag="TVW11_000100"
     CDS             complement(2978..3697)
                     /locus_tag="TVW11_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1364252.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3837..5656
                     /locus_tag="TVW11_000101"
                     /pseudo
     CDS             3837..5656
                     /locus_tag="TVW11_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
     gene            5674..6159
                     /locus_tag="TVW11_000102"
     CDS             5674..6159
                     /locus_tag="TVW11_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1364253.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            6205..7086
                     /locus_tag="TVW11_000103"
     CDS             6205..7086
                     /locus_tag="TVW11_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1364254.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            7073..7891
                     /locus_tag="TVW11_000104"
     CDS             7073..7891
                     /locus_tag="TVW11_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1364255.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            7895..8299
                     /locus_tag="TVW11_000105"
     CDS             7895..8299
                     /locus_tag="TVW11_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1364256.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(8403..8663)
                     /locus_tag="TVW11_000106"
     CDS             complement(8403..8663)
                     /locus_tag="TVW11_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1364257.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(8788..9720)
                     /locus_tag="TVW11_000107"
     CDS             complement(8788..9720)
                     /locus_tag="TVW11_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1364258.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(9730..10158)
                     /locus_tag="TVW11_000108"
     CDS             complement(9730..10158)
                     /locus_tag="TVW11_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364259.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            10416..11441
                     /locus_tag="TVW11_000109"
     CDS             10416..11441
                     /locus_tag="TVW11_000109"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1364260.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            11502..11948
                     /locus_tag="TVW11_000110"
     CDS             11502..11948
                     /locus_tag="TVW11_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1364261.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            12277..12570
                     /locus_tag="TVW11_000111"
     CDS             12277..12570
                     /locus_tag="TVW11_000111"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1364262.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            12551..13783
                     /locus_tag="TVW11_000112"
     CDS             12551..13783
                     /locus_tag="TVW11_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1364263.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQIAKQGMGLVFDVGHGEKTRLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFFGRLRHLKDKSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLAGNLFASLLARAKPYIAARLPNPYYRVLLVGGFLSLSLLLCH
                     YGRYSGLGTNLITAAFSHQPIANYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNATAYFIVIAFAYMV
                     SRRHSIYTKQRVTTSIAS"
     gene            13929..14276
                     /gene="rplS"
                     /locus_tag="TVW11_000113"
     CDS             13929..14276
                     /gene="rplS"
                     /locus_tag="TVW11_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1364264.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            14791..14862
                     /locus_tag="TVW11_000114"
     tRNA            14791..14862
                     /locus_tag="TVW11_000114"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14824..14826,aa:Arg,seq:cct)
     gene            complement(14986..15789)
                     /locus_tag="TVW11_000115"
     CDS             complement(14986..15789)
                     /locus_tag="TVW11_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1364265.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
     gene            16417..16632
                     /locus_tag="TVW11_000116"
     CDS             16417..16632
                     /locus_tag="TVW11_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1364266.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            16629..17405
                     /locus_tag="TVW11_000117"
     CDS             16629..17405
                     /locus_tag="TVW11_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1364267.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVLGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(17474..18730)
                     /locus_tag="TVW11_000118"
     CDS             complement(17474..18730)
                     /locus_tag="TVW11_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1364268.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(18816..19775)
                     /gene="nrdF"
                     /locus_tag="TVW11_000119"
     CDS             complement(18816..19775)
                     /gene="nrdF"
                     /locus_tag="TVW11_000119"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1364269.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(19920..22079)
                     /gene="nrdE"
                     /locus_tag="TVW11_000120"
     CDS             complement(19920..22079)
                     /gene="nrdE"
                     /locus_tag="TVW11_000120"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1364270.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(22100..22318)
                     /gene="nrdH"
                     /locus_tag="TVW11_000121"
     CDS             complement(22100..22318)
                     /gene="nrdH"
                     /locus_tag="TVW11_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1364271.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            22740..23003
                     /locus_tag="TVW11_000122"
     CDS             22740..23003
                     /locus_tag="TVW11_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1364272.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            23008..24741
                     /gene="ptsP"
                     /locus_tag="TVW11_000123"
     CDS             23008..24741
                     /gene="ptsP"
                     /locus_tag="TVW11_000123"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1364273.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            24943..26370
                     /locus_tag="TVW11_000124"
     CDS             24943..26370
                     /locus_tag="TVW11_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1364274.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            27023..28237
                     /locus_tag="TVW11_000125"
     CDS             27023..28237
                     /locus_tag="TVW11_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1364275.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            28333..28902
                     /locus_tag="TVW11_000126"
     CDS             28333..28902
                     /locus_tag="TVW11_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1364276.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            28903..30855
                     /gene="gyrB"
                     /locus_tag="TVW11_000127"
     CDS             28903..30855
                     /gene="gyrB"
                     /locus_tag="TVW11_000127"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1364277.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            31004..32728
                     /gene="ezrA"
                     /locus_tag="TVW11_000128"
     CDS             31004..32728
                     /gene="ezrA"
                     /locus_tag="TVW11_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1364278.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            33100..33381
                     /locus_tag="TVW11_000129"
     CDS             33100..33381
                     /locus_tag="TVW11_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364279.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(33566..34021)
                     /locus_tag="TVW11_000130"
     CDS             complement(33566..34021)
                     /locus_tag="TVW11_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1364280.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            34252..35559
                     /gene="eno"
                     /locus_tag="TVW11_000131"
     CDS             34252..35559
                     /gene="eno"
                     /locus_tag="TVW11_000131"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1364281.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(35695..35931)
                     /locus_tag="TVW11_000132"
                     /pseudo
     CDS             complement(35695..35931)
                     /locus_tag="TVW11_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            36140..36361
                     /locus_tag="TVW11_000133"
     CDS             36140..36361
                     /locus_tag="TVW11_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1364282.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            36363..36623
                     /locus_tag="TVW11_000134"
     CDS             36363..36623
                     /locus_tag="TVW11_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1364283.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            37276..37881
                     /locus_tag="TVW11_000135"
     CDS             37276..37881
                     /locus_tag="TVW11_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1364284.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            38349..41129
                     /locus_tag="TVW11_000136"
     CDS             38349..41129
                     /locus_tag="TVW11_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1364285.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYPDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(41551..41688)
                     /locus_tag="TVW11_000137"
     CDS             complement(41551..41688)
                     /locus_tag="TVW11_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1364286.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      41932..42050
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            42048..42554
                     /locus_tag="TVW11_000138"
     CDS             42048..42554
                     /locus_tag="TVW11_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1364287.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            42651..44609
                     /gene="ligA"
                     /locus_tag="TVW11_000139"
     CDS             42651..44609
                     /gene="ligA"
                     /locus_tag="TVW11_000139"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1364288.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            44622..45644
                     /locus_tag="TVW11_000140"
     CDS             44622..45644
                     /locus_tag="TVW11_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1364289.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            45653..47953
                     /gene="pulA"
                     /locus_tag="TVW11_000141"
     CDS             45653..47953
                     /gene="pulA"
                     /locus_tag="TVW11_000141"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1364290.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            48100..49979
                     /gene="glgB"
                     /locus_tag="TVW11_000142"
                     /pseudo
     CDS             48100..49979
                     /gene="glgB"
                     /locus_tag="TVW11_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            50046..51185
                     /locus_tag="TVW11_000143"
     CDS             50046..51185
                     /locus_tag="TVW11_000143"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1364291.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            51175..52308
                     /gene="glgD"
                     /locus_tag="TVW11_000144"
     CDS             51175..52308
                     /gene="glgD"
                     /locus_tag="TVW11_000144"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1364292.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            52305..53735
                     /gene="glgA"
                     /locus_tag="TVW11_000145"
     CDS             52305..53735
                     /gene="glgA"
                     /locus_tag="TVW11_000145"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1364293.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            53754..56150
                     /locus_tag="TVW11_000146"
     CDS             53754..56150
                     /locus_tag="TVW11_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1364294.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            56492..56689
                     /locus_tag="TVW11_000147"
     CDS             56492..56689
                     /locus_tag="TVW11_000147"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1364295.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            56723..57439
                     /gene="atpB"
                     /locus_tag="TVW11_000148"
     CDS             56723..57439
                     /gene="atpB"
                     /locus_tag="TVW11_000148"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1364296.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            57457..57951
                     /gene="atpF"
                     /locus_tag="TVW11_000149"
     CDS             57457..57951
                     /gene="atpF"
                     /locus_tag="TVW11_000149"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1364297.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            57951..58487
                     /locus_tag="TVW11_000150"
     CDS             57951..58487
                     /locus_tag="TVW11_000150"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1364298.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            58503..60008
                     /locus_tag="TVW11_000151"
     CDS             58503..60008
                     /locus_tag="TVW11_000151"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1364299.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            60026..60901
                     /locus_tag="TVW11_000152"
     CDS             60026..60901
                     /locus_tag="TVW11_000152"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1364300.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            61069..62475
                     /gene="atpD"
                     /locus_tag="TVW11_000153"
     CDS             61069..62475
                     /gene="atpD"
                     /locus_tag="TVW11_000153"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1364301.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            62488..62904
                     /locus_tag="TVW11_000154"
     CDS             62488..62904
                     /locus_tag="TVW11_000154"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1364302.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        17816 a        11958 c        14765 g        18472 t
ORIGIN      
        1 gttagaggtg ttagtatgat aaaggaacag ccactctact tacaaattgt tgatgtatta
       61 gaggtcaaaa ttagaaatac catgtcagct aatgataaat tgttatcaga acgagagcta
      121 agtgacttat ttggtgttag tcggataacc attagattgg cacttaagga gctagagctg
      181 cgtgggctta tttacaaaca gcagggcaag gggacctatg tatcaggcat aaaggagcct
      241 gctacagacc tgtcctcagc ctatagcttt accgaagaga tgaaaaagca aggtcgtaag
      301 cctcaaacag tcattctttc atttgaaaaa atcaagacca cagcttactt gtctggtatg
      361 ttagatttag atgttgatac tgatgttttt gagctagagc gtctaaggat tgcagatgga
      421 aagccattaa tgtttgagcg cacttatata cctgaaaggg gatttgaggc gataacgatt
      481 gatttattgg aaaaaaagcc cttatatgat gtgtttgctg aggattttca ggaagctatc
      541 cgattggctg atgaggagtt ttacgctagt atcgctctag attatgaagc aaagctatta
      601 gggatcaaaa agggggatcc tgtgctgcat attatgcgta agacctataa tgagaaaaat
      661 aggctaatcg aatttacctt tagtattgct agagcagacc agtttaggta ccgtatccag
      721 caccacccta acaagaagat ataggaggta aggaaatgtt tacaaaaaca caagcagaac
      781 tagagctact tggcgcagct atcaccacta gagaaatcaa gcagcagcca gagctatggt
      841 cagaggtctt tgagtctttt ctgaagcaaa aaaaagacct cttagccttt tttgacagga
      901 ttattgaaag cgctaacaga aacaaggtaa aaattatttt tacaggagct ggaacttctg
      961 aatacattgg caataccatt tgtcattatt tggagatgac tggtgacagg gaaaattatt
     1021 tatattacag cattgcttcc acagaccttg ttgcagctcc aagccagtat ctctttgaag
     1081 aggatacagt cgtgcttgtt tcctttgcaa gaagtggcaa tagtcctgaa agtgtcgctg
     1141 ctgttagtct tgttaatcag ctggtgtcaa atccttatca tttggtgata acctgtgcca
     1201 aagagggggc cttagctcaa aatgctaaga aggacaaaag gagctattta ttcttgctgc
     1261 ctgaggcctc aaatgacgct ggctttgcta tgacgggaag ctttagctgc atgatgctag
     1321 cggccttgtt gatttttgat caagcgcatt cccttgagga gaaaaaatgc tatttagatc
     1381 agattgtagg tatggtggca gctattattc agcaggaggc tgatttacaa aagctggtta
     1441 gcttagagtt tcaacgcttg gtttacctgg gatcaggagc cttagcgggg cttacgcaag
     1501 aggctcaatt gaagatttta gaattaacag ctggcaaaat tgcaacagtc tatgactcct
     1561 caatgggctt taggcatggt ccaaagtcat ttattgatga tcagacattg gttattggtt
     1621 ttgttagcaa tgatccttat acgagaaggt atgaccttga tgttttagaa gagataagag
     1681 aggatgctat tgctgttgat acggttgcat tacagcagca aggaggtgag ggctttagtg
     1741 ggcattgctt tggcttagac tcgtcaatgc tattgccaga tgcttatttg gcctttccgc
     1801 ttgtttttat cgcccaaacg cttgctttgc tgtcgtctat taaggttaat aatttaccag
     1861 atactccttc ggccacagga acggttaaca gggttgtcca aggtgttaag atttatcact
     1921 attttaagta ggagaacaag atgtaccatt tatcaaaagc taagtatcgt cttcttgaaa
     1981 aggtcagtcg taagggcatc atttcggcct tggcctttga tcaacgcggg gttttaaagc
     2041 gcatgatggc agcccaccaa gacacagagc caactccttg gcaaatcgaa gccctaaagg
     2101 ctctggtatc agaggagcta accccctatg cctcctctat cctgctagac cctgaatatg
     2161 gcctgccagc caccaaggtg cgtgatgaga agtctggctt attattagcc tatgaacaaa
     2221 ccggctatga cacaaccacc actagccgcc tgccagattg tctggtggac tggtcagtca
     2281 agcgcctcaa ggaggccgga gctgacgcag tgaagttctt gctgtactat gatgttgatg
     2341 gtgatgagcg tattaaccaa caaaagcagg cctatatcga gcgtatcggc tcagaatgtc
     2401 aggcagagga gataccattt ttccttgagc tattgaccta tgatgaggcg ataacagaca
     2461 atcagagtgt agcttttgcc aagctaaagg cacacaaggt taatgaggcc atgaaggtct
     2521 tttcaactga gcgctttggg gttgatgtcc taaaggtaga ggttcctgtc aatatggcct
     2581 atgttgaggg ctttgcagag ggtgaggttg tttacagcaa agaggaggct atgcaggcct
     2641 ttcgtgacca agaggcagct agtcacttgc cctatattta tttgagtgcg ggtgtatcag
     2701 ctagtctgtt tcaagagacc ttggtttttg cggcagaggc aggagctagg ttcaatggtg
     2761 tgctgtgtgg tagggccact tggtcaggag cagtagcggt gtacatgtca gagggcgagg
     2821 aggcagcgcg tcaatggctt cgcacagagg gttttgaaaa tattgatcgt ctcaatcagg
     2881 tgcttgagaa aacagccagc ccttggacaa caaagcttac tcttgatgaa gcctagtaaa
     2941 ggcatgataa aagcaatact aggacattgc ttctgtatta ttggtaatca ctggaggaca
     3001 aggcgtactt gaaaaattgc caatgcttgt aggactcggt gtactctaga atacggccat
     3061 tatctgtcga ccgagtgagc ttggtttgaa ggacacaagg agtgttgtct atcatgttta
     3121 aaaatgtagc gacatcttta ggcatgtgat ccgtcagctg tgtttgctgg gtgaagcttt
     3181 gtgatcgcat ttgaatgtga aaatccaaaa agaagcgctt ataaagcgac tggtaatcag
     3241 ctaaatcacg ctcagggcac agcaggtaat catgaggaat ataagatagc tggtataaat
     3301 agggctgctg attaatcgtt cgtgtacggg agatggtgta gtaaaattcc gttttatgaa
     3361 gtttcaagag atttagatag tagggatcat ttcccttaac tacactaagg acagtcacct
     3421 cctctttttg atccttaaag gtacctagat aggaaaattg gactagctgt tcttttctgg
     3481 tacgggtaat gaaggttcca agtccctgcc ttcttctgat aaagccttct ttttctagtt
     3541 ctttaagggc tcgaatgatg gttatggagc taacatgaaa gcgtttaatc agctcggctt
     3601 cggtataaaa tttgtccccg gtatggtagt ggccattcag aatttggttt tgcaattctt
     3661 ctttgattag tcggtacttt gggtatttga tggtcatagt tactcactca ataattgttt
     3721 agtacgatta tagcaaaaat agtaagctga tgtcatatct taccagttat tgctcagata
     3781 gcttgtcaat cagtcattga tcaaaggctg atggttaatg aataaaagga gataatatga
     3841 agcaattttg cataaaggag cagttttacc ttgatggcaa gccgtttaag atattatcag
     3901 gtgccattca ttactttaga atagctcctg atagctggtc tagggtgctt tatcagctga
     3961 aggccttagg ctttaataca gtagaaacct atattccttg gaatatgcat gagccaagga
     4021 agggacagtt tacctttgag gggattgcag atgttgaggc atttttggat ttggcacagg
     4081 aatgtggcct atatgctatt gtcagaccct ctccttatat ctgtgctgaa tgggagtttg
     4141 gtggtttacc ggcttggcta ttaactgaaa attgtaggct cagatcaagc gatgaggtct
     4201 ttcttaagca tgtatcagat tattatgatg tgttactacc aaagctggtg aagcgtcagt
     4261 tagataatgg cggcaatatt ctgatgtttc agcttgaaaa tgagtatggt tcttatggtg
     4321 aagaaaaggc ttatttaaga aaattaaaag agcttatgct tgctaaaggc attagtgccc
     4381 ctctctttac ctcagatggg ccttggccag ccacgctagc atcagggagt ctgattgacg
     4441 atgatgtttt tgtgacaggc aactttgggt caaacgcttc aaagcaattt gccagtatgc
     4501 aggatttttt ccaagcacat caaaagcaat ggcctctgat gtgtatggaa ttctggttgg
     4561 gctggtttaa tcgctggaat gagccaatca ttcgaaggga ctccaaggaa gctgttgatg
     4621 caatcatgga agctatagag ctaggcagca ttaaccttta tatgttttgt ggtggcacta
     4681 attttggctt tatgaatggc tcgtcagctc gtctgcaaaa ggatttacca cagataacct
     4741 cctatgatta cgacgcatta ctagatgagg cagggaaccc gacaaagaaa tataccctgc
     4801 tgcaagaatg tactgacccc caaaagttag acataaaatc taacaattgg ggggcagttc
     4861 agaacgtctc aaggagtgtt accctcaatt atcctttgca gagccaatga tcagttctac
     4921 gatggcctta gagtctatca agttgtcggc aagggttagt ctttttaaga caatcaaaaa
     4981 tgtaagcgct atcaagaaaa gtttttatcc ttgtaatatg gaggagctag atcaaccaac
     5041 gggctaccta ctgtatagaa cgcacctcgc tagacatagc aaggaggagc ggctcagggt
     5101 cattgatgct agagaccgca ttcagctctt tttagatgaa aagcacgtga aaacccagta
     5161 tcaggaggaa atcggtcagg atatactgat acatcaagag ggtgagacca cacagcttga
     5221 tattttagtc gaaaatatgg gacgtgtcag ctatgggtac aagctgacag caccaagcca
     5281 acaaaaagga ttaggcagag gcttaatggc tgacttgcat tttgtaggtg attgggagca
     5341 ttttccacta gattttcaag agctggattg gattgatttt tctgcaggtt ggaccgatga
     5401 ggtgccagga ttttacgcct atgattttga ttgtcagcag ccggcagata cctaccttga
     5461 tttgagtcaa ttcggaaaag gaattgccct tgtaaatggt gttaacctag gacgtttttg
     5521 gaaggtcggt ccaacattat cgctttatat tcctaaggga ctattaaaac aaggtcaaaa
     5581 tagactgctg atatttgaaa cagaagggca gtttagtgag tcaattcgtt taactaagga
     5641 accaatttat aaatagataa aaggagaaaa cttatgacaa ttgttgcagc acgtattgac
     5701 ggccggttaa ttcatggtca ggtagctaat ctatggacga caaagctaaa cattagccgt
     5761 atcatggtgg tcgataatga ggtgattagc aatgaccttg aaaaaacagc actgaagcta
     5821 gccacaccta gcggtgttaa attatctatc ttatctgttg aaaaagcagc caacaatatt
     5881 ttggaagggc gctatgattc tcaacgcttg ttgatagtag ccagaaagcc ggatagcttt
     5941 ttggagctga ttcaaaaagg ggttgctatt tcagagttaa atgtcggcaa tatgtcacag
     6001 acaccggaga ctcgtccagt aacgcgttct attaacgttg tagacgagga tatagaggca
     6061 ttcaaggcta tttcagccaa agggtgtcat ctcattgccc aaatggtgcc taatgatgcc
     6121 ccagcagact ttatgccgct gttggataag gttgattaag atgtgtcaaa tcaaaaacga
     6181 atctgtttca ggaggtaaaa gcttatgatt caatggtggc aaatcctatt attaacactc
     6241 tactcagctt atcaaatatt agatgagcta acaattgtct cttctgcagg ctcacctgta
     6301 tttgcaggat ttatttcagg tatcatcatg ggagatgtgc aaaccggtct ttggattggt
     6361 ggtagccttc aattgatggt gcttggtgtt gggacctttg gaggagcttc gcgtatcgat
     6421 gcaacctctg gtgcggttat tgcgacagcc ttctcggttg ctcaaggcat agagccagaa
     6481 ttagcgattt caaccattgc agttccggta gcggccttgc tggtttatac tgatattcta
     6541 ggacgctttt caacgacctt ctttgctcac cgtattgacc gccatgttga aaactttaac
     6601 taccgaggca tcgagcgtga ttaccttatg ggagctgtac cttgggccct atcacgtgct
     6661 ctgccggtat ttttagcggt ctctttaggt ggtggtgcgg ttgatacagt tgttaagttc
     6721 attgaccatt atgaatggct agcaaatggt ctaactcttg caggaaaaat gcttccaggc
     6781 ttgggctttg cgatcttgct tcactaccta ccagttaaac gtaatctcca ttatctggct
     6841 ttaggttttg gcttgacagc aatgctaaca accatttaca ccaaccttca ggtagctgga
     6901 ggcgcccttg caggagtagc caaggatttc aatgccgcac cattcaaggg gctgccaatg
     6961 attggtattg ctattattgg gctttccttg gcaaccctcc attataaaaa tggtcaacaa
     7021 gcacctgtag ctgaacaaaa acctggggta tcagaaagtg gggaaattga agatgacgaa
     7081 atctaattat aaattaacca aacaggattt taatcaaatc aataagcgca gcctgttcac
     7141 attccaatgg ggctggaact acgagcgtat gcagggctct agctatcttt acatgatttt
     7201 accacagctt cgtaagattt atggcgatgg aactccagag ctaaaagaaa tgatgaagac
     7261 gcacacgcag ttttttaaca catcaaattt ctttcatacg attatcacag gaattgactt
     7321 ggcgttggag gaaaatgaag gacttgcctc aaaagatgct gttaatggga ttaaaacagg
     7381 cttaatgggg ccatttgctc caattggtga ttcggtcttt ggctccttag taccagctat
     7441 tatgggctct atagccgcag gtcttgctaa agaaggggtt tggtcaggga ttactggtgt
     7501 attgatgtgg gtatgtactc agatgatcat caatgtgttt cgttggaagc agcttgaaat
     7561 tgcttataaa gaaggtacaa agctcgtcac caccatgcgt gataagctaa ctgctgtagt
     7621 agatgcagcc tcagtcatgg gagtattcat ggtaggggcc ttaattgcaa caatgattaa
     7681 ttttcagttt accgcagcac ccaaaattgg agagaaagtt atcaatattc aagatttaat
     7741 tgataccatt tttccacgtc tagttccagc cttatttacc ggaggtatct tctggctgct
     7801 agggcgtaag ggcatgtcac caactaaggc aattgttgtg attattttat ttgccttagt
     7861 gatgtcttat ttcaatattt taggagtata gctgatggcg caaaccttaa ttctcattag
     7921 tcatggagct ttttgtcgag agctaaaaca gagtacagaa atgattatgg ggccacagga
     7981 caatatttta acagcagagc tgcaaccaaa cgaaggtgcc gatgacttta aagaaaagct
     8041 tttaaggcta attgcaggtt tagatgacgt ccttgtgttt gcagatttga tgggtggaac
     8101 accctgtaac gttgccagtc gtttgttaat ggaaggacat cagtttgagc tgtacgcagg
     8161 catgaatatg ccaatggtca ttggtttcat taatgcctgt ttgatcggtg aagcgtttga
     8221 tttcaaagcc tttgcctgtg acaatattca ccatgtcaat accattattt cagctctagc
     8281 agatgatgat gacgactaac caagctcgct tatttgtcac gcaccttacg gagcgaaacg
     8341 gaccaagagc cgcataatca aaaaagacac tgccaaatct tggcagtgtc tttgctgtaa
     8401 gcttattttg ctgcgtttgc gtctttgaga ccgtatttct tgttgaaacg atccacacgt
     8461 ccatcggctt gtgtaaactt ttgacgacct gtgtagaatg ggtgtgagtc tgatgaaatt
     8521 tctacacgaa caagagggta agtttcccct tcaaactcaa tggtttcttt agaggtctta
     8581 gttgaaccgc taaggaattt gtagcctgta gttgtatcaa ggaaaacaac tggacgataa
     8641 tctggatgaa tgtcttttct catcttaaaa aagttccttt ctgccatgat actgtccgta
     8701 tcatagttat taactactct agtttaacaa aagttagtaa gcttgacaag ctttttctat
     8761 cactattcat caataagatg ataagtctta tgttaagaga tcaatcagct cttggtagat
     8821 ttgctcattt tcctctaagc ctgatgacgt ggcaccgcta gcaagagggt gcccgcctcc
     8881 ttgatgacgc ttagcaatac cattgatgac cttttcttta ctgcgcatgc gtactcggta
     8941 ctggccatct ggcagctcaa caaagataac ccaagcctgc accacgtcta tttttccagg
     9001 agcagagaca atcgctgagc tttctgccaa gctaatacca aaggaattta ggacctcctg
     9061 gctaagcagt aggcgggctg caccactgtc atctatatca agctgctcaa aaacatagcc
     9121 ttgtagcttg gcaattttaa gtggaaagga atccatctgc ctcgaaatag cagcaaagtc
     9181 aaaggcataa tttcttaatt ggcttgcaat ggccagtgtt ttactgcttg ttgaggcata
     9241 gagaaagcgt cctgtatctc ccacaatgcc agtatataat agtctagctg cctcatcagt
     9301 taaagccaag ccttggctaa aggcaaattc agcaataatc tcactagcac ttgaggtctt
     9361 ggtgtcaacg taggagagat caccatagac atcatcgtta gggtgatgat caattttaat
     9421 gaggcaagcg cccattgtgt agcgctcatc atcaatgcgg gggcgattgg cagtgtctgt
     9481 aacaatcact aaagcttcct tataatcatc gtcggacacc tgatccatga gactaatcca
     9541 agccagacta ggctcatcaa agcctgttat caggaccttt ttgtcaggga aattatgcct
     9601 gataatctct ttaagtcctg cttggctccc tagagcatct ggatcggggt tttggtgccg
     9661 atgaatgatg atggtttgat agtgcttaat gtgttctaaa atagtttgaa acgttgtcat
     9721 aggtatcctt tagtttttga tcatatcaat gtgaggaata ttgtcttcca gataaatctc
     9781 agagactgct ttaaacccaa atgagctgta aaaaggctca agataagcct gcgcttgagc
     9841 gtagacggga agctttggaa agtgctgttg acaataggct aaggcttgat gaactaagtc
     9901 acgtcctagt cctgttcgcc ttgcattttg tgctaccagt actcgtccca gctttatgct
     9961 attgtcagtt gggattaagc gacagtaggc cctaagctct gaatcaacct gcttgaaaag
    10021 atggatagct ttttgatcca aatcgtcaat atcaggatag ggacattgct gctcaaccac
    10081 aaaaacagcc acacgctctt tatagatggc aaacaattca tcttttgtta actgatcaaa
    10141 tgctttaaca acccacatta gctagcctcc aaaatcactg gtacaatttc ctttatgata
    10201 acataatagc atatatcagc cataatggaa cgaaaaaaac ctgactctta atggacgatg
    10261 tcgtgatgat aattacatct tgtctcaaaa gctggtaatc atcacaggca cagaaaaatg
    10321 tgccccttct gttgcttttt gagaaaaagt tcacttgctt tttggtagtt ttttggtatc
    10381 atactaaaaa atagacttaa ttaaggagat acagcttgga aacaaaagat ttaaagaagc
    10441 ttgctaaagc tgagctgcac tgccatttag acggttcttt gtcattagac actattcgtc
    10501 agttggcggc tttggcgcag gtagatgttc ctcaagatga ttctgagtta aagcagctgg
    10561 taaccgcacc ggaaacctgt gaatccttga tggattattt aaaaaccttt gatgttatca
    10621 gaccattatt acaaacgcct caggctttaa cattggctgc ttatgatgtt gtgaagcagg
    10681 ctgcccttga aaatgtcatc tacattgaaa ttcgatttgc tcctgagttg tcaatggatc
    10741 agggcttgac cgccactcag gtggtagagg cagttttaaa aggactcgag caaggacaaa
    10801 aagagtttgg cattgtcgct aaggctattg tgtgtggcat gcgtcagtcc tcactagaca
    10861 ttagcagaga gatttttgca aatgtcttag agtgggccaa taaaggcttg gtaggctttg
    10921 attttgcagg caacgagctg gactttcctc cagctgtctt agcagatttg atcaaagaga
    10981 cgcaggccta tgggttacca tttacgcttc atgctggtga gtgtggctgt ccaaactata
    11041 ttgttgatgc tattgattta ggtatcaaac gcttagggca tgtgacggcc attcataacc
    11101 aaaaggattt attggccaag tttatcgcca atgatgtgac agcagagctg tgcttcacta
    11161 gtaatctaca aaccaaggct gctaggactg ttgaggactt tccttatatg cagctaaggc
    11221 aggctggcgc taaattatcc attaacacag acaatcgaac agtatccgat accaatctga
    11281 caaaggaata tgaactgttt gtcaagcact ttgagacaag cgtcacagac tttttagagc
    11341 ataatcgtga tgctattaag gctagttttg ccagtccggc tgaaaaagaa gctttattgg
    11401 atcgtttgga aaaggcttat cagtcttaca tcaagaaata atgcttttct tggcaaagta
    11461 tgataaaata tactgacatt tagttatttt gggaggaaat tatggcatta gccaaaatcg
    11521 tttatgccag catgacagga aatactgaag aaattgctga tattgttgct aataaattgc
    11581 aagaattggg acatgatgtt gaggttgacg agtgtacaac agttgatgct tcagagcttg
    11641 aggctgctga tatggcaatc gttgcgacct atacctatgg tgatggggac ttaccagatg
    11701 agattgtcga cttttatgag gacttgcagg atttggattt gtcaggcaag atctacggtg
    11761 tcgtgggctc tggtgatacc ttttatgatt atttctgcaa atcagttgat gattttgacg
    11821 aacagctcgc tgccactggt gccactaagg gagctgactc ggttaaggtt gatttagctg
    11881 ctgaggaaga ggatattgct cgcctagaat cctttgctga gcaaatgtca caggcattag
    11941 aggcataagt aagacttttg atacagattg gtaaaacggt cagtggaggc ttgcgttttt
    12001 taccaccaaa tgcatgaaaa actgatattt tctgatcgtt ttttcatgac tatgtgctct
    12061 ttttcaagaa aagtcatgcc attattagcc tgaatgcaaa caattgatag tgtcaaaatg
    12121 ttgatcatat agtaaaaaaa tgcatgtgac tagaaagcag ttacatgcat tttcgtcatg
    12181 cgtttgtcgt gaggcatttt gggggttact tgcttactga gctgaaattc actataataa
    12241 aaagataaat aaagaaaaga agaagttagg tgaatgatgg gattagagac catacgacaa
    12301 gacattaatg ctgttgatcg tcagttgatt gctttgctgg aaaagagaat ggtcttggct
    12361 gaccaagtag cggcctataa gcaggtacat gatgtgccag tgcttgatca agagcgagag
    12421 gctgaggtcc taaggagcgt gtcacagcag attcggcata aggcctttga gcctgccatt
    12481 cttgagctat ttaagacaat tatggcagta tcaaggcgtt atcaggctga gcaaatagcg
    12541 gttggttcaa atgatgatga agcctattaa aaacaatcaa gacatcagta taggtgataa
    12601 tgtctatttg gcttttgcag ccctgctcgt tggggtggtg gtaggtgtga tagatactgt
    12661 ttttggacaa ggcttgttgc tcttgtctgc tgttcgtgat gctcatctca tttacctgtt
    12721 accctgctta gctcttgctg gacttgtgat tgtgttctta tatgagcaat atggccaaat
    12781 cgctaagcag gggatgggct tagtttttga tgtggggcat ggtgaaaaaa caagactacc
    12841 actggtgttg attccgttga ttatcctctc aacctggctg acgcatttat gtggaggcag
    12901 tgctggtcgt gaaggcgtag cggttcaaat tggagcgaca gtgtcacatt tttttggacg
    12961 tcttagacat cttaaggaca agtcacagct gtttttagtc atgggaatgg ccgcaggctt
    13021 tgcgggctta tttcaaacgc caatgacagc ggttgttttt gccttagagg tcctgttgct
    13081 aggaaatata agctatttag ccttgctacc ttctcttata gcagccttta ccgcctcttg
    13141 gacctctcat tgcctaggct tagaaaaatt ttcagtcccg atagccaagg ccttgaaaat
    13201 caccccgata acctttggga aattagtgct actaggcctt atttttggct tggctggtaa
    13261 tctttttgcc tccttgttag caagggctaa gccatacatt gcagcaaggc tgccaaatcc
    13321 ttattatcgt gtgttgcttg ttggtggttt tctatcgctt agcctgctgc tgtgccatta
    13381 cgggcgctat agtggcctag ggactaactt aattacagcg gcctttagtc atcagcctat
    13441 tgctaattat gattggctat taaagctctt gtttaccatt atcactctct cggctggctt
    13501 tcagggcggt gaggtcactc cactttttgc tattggtgcg gctttaggaa ttgtcctagc
    13561 accatggctt ggcttgccgg ctcagttggc tgcagccctt ggctatgctg cggtatttgg
    13621 cagtgccacc aatacctttt tagccccgat atttgttgga ttagaggttt ttggtgcaac
    13681 aaacgcaact gcttacttta tcgtgatagc ctttgcttat atggtgagcc gaaggcattc
    13741 aatctacact aagcaaaggg tgaccactag catcgcttcc tagtgtcttg gtcagttttt
    13801 tggagaaaat agctttacaa gtggggctta ttttgttaca ataggctccg tgtgtaatgg
    13861 acgcacaaaa attacggcta atccgctaag actcgcgctt aagattagta agataaggag
    13921 aataaacaat gaatccatta attcaaagct tgacagaggg tcaacttcgt actgatattc
    13981 ctagcttccg tcctggtgac actgttcgtg tgcacgcaaa ggttgtcgaa ggatctcgtg
    14041 aacgtatcca gatctttgag ggagtagtca tttcacgtaa aagtcaaggt atctcagaga
    14101 tgtatactgt tcgtaagatt tctagtggta tcggtgtaga gcgtaccttc ccaattcaca
    14161 caccacgtgt tgaaaagatt gaggttgtgc gtcatggtaa ggttcgtcgt gctaagcttt
    14221 actacctacg tgccttgcaa ggtaaggcag cgcgtatcaa ggaaattcgt cgctaaaaag
    14281 agcatacgag aggtttttca ctgtcttatg aaaggactgc tggagcagca gggtctttgg
    14341 gacaagcttt ttttcgcagg tatgtgaacc tacgctcaat tcaagacata tcaaaggctc
    14401 attctatgat agagtgggct ttttgattgt gatcatgctt tagtgcctaa ataaatgaca
    14461 gcagcctgac taatgaaagg cttacttgac tttggaaatg ctcaaggctt gcgctaccag
    14521 atagaagctg acatcatgcc atagcagtca aggggaagaa ggactagatt ttttggcgag
    14581 gtgttgatct gtgaccctga tgttgttggg aatatgagag taatttaaaa tttcgtcttg
    14641 cattctacct ttttctaggt tacaatagac aagtaacctg attagtgaag ctaaaagacg
    14701 tagcgatggg ttctaaaaaa gaatgattct ggcgtttttg gctaacctaa gctgatagct
    14761 ttgctaggca gtgtcttagt catctggtca gtcctgctag tttaacggat aaaacaagcg
    14821 cctcctaagc gctagctgtg ggttcgattc ccgcgcggga cattaaaaac aaagtaaaaa
    14881 gagtctgaga aggtttgagc tgcccctaat tgttagattt ttttctaact cttgaagtgt
    14941 gggtcaaaga ctatttgtct caggactctt tttaattggt ttttactaag ctgcttcatc
    15001 tagttcttca gttgctaagt tgtttccttc ttctgtatgt tggttttcat caagtagcat
    15061 tcctgtgcgg taatctaatg ctgccaaagg tgatacatta tccagaacaa ctgaggttat
    15121 accataatga tcaacggatt ctttgttgcc tcccaatttg atttggagga gctctccgtt
    15181 ttgatcaatt ccaacgtact gtaacactac ttgacgagga actaattcat cattctgata
    15241 aataggagtt accttataat ctagccaaaa gttagggtgt atggctaacc aattgtctag
    15301 tctattttca taataaagca ttcctaaagg atttttatca ctaaaacctg tattaaggta
    15361 ttttgtcata gtaactaaat ttttgggttc atcatttagg ccgctaaact gataaccgac
    15421 tagatgtccg cgatccatta accaagtctt tttccctcta gaattaatga cttgatagtt
    15481 atgccagccg ggaggattaa atctaagcgc ttttcttttg agagttggtt catcttgatc
    15541 tttgagttgt atgtgtgcat aggtggctct ttgtaaatga tcaagatctc ccagagctat
    15601 ttggtatttt ccagtaaacg gtaaaattcc tggtatttcg gtagcttttg ttcccaatga
    15661 tatttccgtt gtatctggga aggttctaag ttttcttgca gattgaacag agttagctgt
    15721 gaaaatagtc agaatagtta acaaaacaat tgttagactt ttccagttac ggcgacgtga
    15781 tttagacata tcaatgccct cctttttttg tttacgagtt aagtatatca cttttaatta
    15841 aaaaaactta aaattaataa aattatttta attataatat tcatctaaat tatctttatt
    15901 tttaattcaa aaatataagc aattgattca cataaacaaa ttgagacgaa cagtagattg
    15961 tagctatatc acaggtgaga tagtaatgat cgtgcgaaac aataaactga tttttccatg
    16021 cgggatattt gttatcagtg agttgaatgg aactagcagc tattgtttta ttgttagtca
    16081 tctagtgttt ttaaggtgct tattttctgt tacaacagtg atgacaacag gttaagctaa
    16141 gttcgatgga gcttggtttt ttattgttac aagaaagctc atagatggtg attgcattct
    16201 tttatcatat gacaatgttt ctatttttga caaatattat tgtcaaaaag taaatgatct
    16261 gttacactgg agttggactc atgaaagaaa aaagtaatca gtaggataac aataacaaag
    16321 ctattttaag cttataccat tgtgtcaatg gattgttgcc ggaaatgact ggtgctttct
    16381 gttcaatcag gagacagcat ttattaggag tgaagcatgg cttataggtt gagaaatcgg
    16441 ctcaaggagc tacgagctag agatggcatt aatcagacgc agatggcagc attagcaggt
    16501 gtttccaggc agaccattag cctcattgag cgaaatgaat acacaccatc tattattatt
    16561 gcaatgaaaa ttgctaaagt atttaatgaa ccaattgaac aagtatttag cttagtggag
    16621 ggcgagagat gaaagctttt atgacggaaa aggacagtac gttggtgaga atacttaagt
    16681 cattactgct tggatcaggg attggcttag tgttaggtgg ccttgttggt tttggtttag
    16741 ctaggtttaa catattagaa aatggctttc cgatatcaga agaagacacc ataactggaa
    16801 taaagtgggg aatgagaccc cttgttatcg tgcttatgct gctgagcatt tatgatattt
    16861 atcaagttgt caaagaatat gctagatatg tcaagctaag cgatgatgaa acagaggagc
    16921 tgtaccgtta cattaatctt aagcatgcct atgctttagg atttagcgct atggctatgg
    16981 tcttgaatat agtcgttttt tctttgggat atagggtgcc tattgctaat aatgctagct
    17041 atcttggttt gacttttcct atttacgagg ctctgatgct tgtggttatt agtgttctcc
    17101 atgcttatat tttgaaggtt tatactcgga ttcgcggggt caagatgacg cttgctccta
    17161 ccttaaagga attaaagcag aatatcttac aacaggacga ggcagaattg caggctaatt
    17221 atcaaatgtc ttttgaggtt gtcttgggcc ttagtggctt tatattacca ggcatttacg
    17281 taatattatt gcttttatct atgatttttc aaagggttga gctgaccgga ctaatcatta
    17341 ctgctagtat tcacctctat attctggtga aatcctttaa atcagcacat gatttttata
    17401 ggtaaggcgt aaggttttac ctactcaaga attgttatac agcaaaaaag ctttgataag
    17461 ccattactgg cgatcaaagc tttttgtgtt tgttgaaaaa gaggcttttt tgaaagagct
    17521 gttggctgag atagcttgtc aaacctacaa ttgcaagcgg cacaaggcta atgagaggtt
    17581 gtccggtaat ttcaatgaga aaaagaggag cagtaagagg tatctgatta atgattccca
    17641 aaaagagggt cgctccaatg acaatggcca agggaagtgg tacagagaga taacctagct
    17701 gattgctaag gcttgccagt agcaagccac tagctcctcc aagcatcata gaaggagcaa
    17761 ttttgcctcc tttagctcca gaggcaaata ctgcatagac agcagctgct ttacttagta
    17821 agagcgaggc ggtataagat aggctgacat catggtgtag cagcaggagg agaccggcct
    17881 tgccattgcc taaaatctct gggaaataaa ggcttaaaca agcactaaag ccaaaagccc
    17941 ctaagacacg agggataaac catcggctct taggctttgc ctttggtgcg ttttggagca
    18001 gctgctggta gcaaaaggcc agaaatgcta agatgggact ggcaatgata gcccaaagga
    18061 ctgttgtcag ttgccaggct tgtgggagaa tgagatactg tatgtcctga tgtccgctta
    18121 gaacaagcac actttgaaca gcagtaaagg cagttatagc tgccgcgtaa atgtgtttaa
    18181 ctgagcattt tttgacaata gcctccatga taaagacaat cgtagctaat ggtgcctggt
    18241 aaacagctcc aagggcagct cctgaagcac aggctaaaag caatccttgc tctgctgctg
    18301 atgcgtttat agctttattg caagcggcag tcagtgccac agcaacctca cgtgaagcac
    18361 cttcacgacc gacaggtgct cccatggaga cggttattaa ttgcagccag ccatgacaaa
    18421 attgtgtcca agggctgaaa tccttttgct gactgagtgt ttgttggata ggctgaatag
    18481 gcttggcttt tttagcaagt agctgccagc cgagaccagc aatagctcca gccaacaata
    18541 gagataaaaa acgcctttct ggagctaccg ttgcaatcat ggtgctaaaa gacccagatt
    18601 ggtatccaaa gctaatagcc tgtatgaaat gaatggcttg agtgagcacg taagccacca
    18661 caccagcaat cacaccagct accaccagtt ggcccgtcca tgttaagaaa gtaatcaatc
    18721 gagtaatcat atcttttatt atagcagata aaaagagcct gagactactc aggctccaaa
    18781 atatagataa atccaatctt catgagaagc tggacttata gcccataatt gtaatcgtca
    18841 tcagtcatag cttcaacagt accaagaagg tagccattac caacttgaga gaagaaatcg
    18901 tggtttgacg tgccggttga aataccattc ataacgattg ggttgacatc attggcagtg
    18961 tctggaaaaa gagggtcctg accaaggttc atcaaagcct tgttagcgtt gtagcgtagg
    19021 aaggtcatca cttcctcggt ccagccaacc tcatcataga gggtcttggt gtattgctct
    19081 tcattttcat atagctgata cagcaggtca tacatccagt cacgaaggct ttcttgctca
    19141 ctctctgata gctcattaaa gcccagctga aacttgtagc cgatataagt gccatgaacg
    19201 gactcatcac gaatgatgag cttaataatt tcagcgacat tagccagctt attgttgccc
    19261 agataataga gtggtgtaaa aaagccagaa taaaatagaa aggtttcgag ataagtcgag
    19321 gctacctttt tttgaagggc actgccattt tcataaatgt cgttgattat cttagcctta
    19381 ttttgaagaa atacgttgtt gttggtccac tcaaaaatgt cttcaatttc ttttttggtg
    19441 tttagggtcg aaaagattga tgagtaggat ttagcatgga cagactccat aaattggata
    19501 ttgttaagaa ctgcctcttc atgcggggtg cgcacgtcct tgcgaatggc ttcgactcct
    19561 gactcagact gcatcgtatc aagaagggtt agcccgccaa agaccttacc tactaaatcc
    19621 ttttcaacag cagataatct gcgccagtca tcaaggtcat ttgatagtgg aatacgtgta
    19681 tcaagccaga attgctccgt cagcttttcc caggttgact tgtcaatgac atcttcgatt
    19741 tcattccagt tgattgcttc atagtatgtg gtcatgagtt tctccggtag attgtaatat
    19801 agggttaggt atgctaggag gagagccttg agtgctggtc tatcattagg acaggtgcac
    19861 tgacacatca gctaggctct gacattaagg actggtccac ctcactgcca ttcacttggt
    19921 tagatgacac agctttcaca ctgattggct ccgacctcct cgccatcatc ggtaaaggtg
    19981 cggatataat agattgattt tatcccttta ttaaaggcgt aatgtctcaa aatagatagg
    20041 tcacgagtgg tttgcttgct ttctgttttc cattcgtaga gctcctttgg caattcgctg
    20101 cgcaaaaaga gtgttaacga cagtccctga tcaacatgct ttgtagcagc tgcatagaca
    20161 tcaatcacct ttctcatgtc catatcatag gcagatgtgt agtaaggaat ggtgtctgta
    20221 gataggccgt tggctgggta ataaatcttg ccgattttct tttcctgacg ttcttcgatc
    20281 cgctgagtaa tcgggtgaat agaagcagag cagtcgttga tataggaaat tgatccatta
    20341 ggagcaactg ccagacggtt ttggtgataa aggccatctg tcataatcgc ttgacgcagc
    20401 gccttccagt ctgctgcttg cggaataaag tgatccttga aaaggctttt aaccagctct
    20461 gattttggca cacattctcc tgtgatgtac tggtcaaaat aagcaccgct agcatatgtt
    20521 gatttttcaa agccaacaaa ggttgtctga cgctcgcgag cgatctgatt ggattcgaca
    20581 agcgtccagt aattcatcag cataaagtaa atatcagtaa attcgataga ttctgggctg
    20641 ccatattcga tatggtgctg agccaaatag gaatgaagcc ccatagcccc aaggccaaag
    20701 gtatgtgctt gactgttacc atttttaaca gttgggactg cttcgatatt agaggagtca
    20761 gtgacaaagg tcagggcacg tgtcatggct ctgatggaac gaccaaagtc aggtgacgtc
    20821 atcatgttta agatattagt tgatcccaga ttgcaggaaa tatcagttcc cattttgaca
    20881 aactcctgcg catcattaat gagactaggc gtttgaacct gtagaatttc tgagcatagg
    20941 ttgctcatga tgattttacc gtcaataggg tttgacctgt tggcagtgtc gatgttgata
    21001 acatagggat agccagattc ctgctggagc ttggaaatct ctgtctccaa atcacgtgct
    21061 ttgatttttg ttttggtgat attaggattg gcaaccaatt cgtcatacat gctagtaata
    21121 tcaatgtagt taaatggcag gccgtattct ctttcaacac tataagggct aaagagatac
    21181 atgtcagcat tgtgacgagc aagctcataa aacttatctg gtacagtaat accaagtgac
    21241 aatgtcttga cccgcacctt ttcatctgca ttttcttttt tggtagacaa aaaagcgata
    21301 atatcagggt gaaagacgct taaatacacc acaccagccc cttgacgctg ccctagctgg
    21361 ttggaataag aaaagctgtc ctcaaatagc ttcattacag gcacaacacc agaagcagct
    21421 ccggcatagc ccttgattgg agcgccagcc tcacgaaggt tggataggct aatgccaaca
    21481 ccacccccaa tacgggataa ttgcaaggca gaattaatag agcggccaat ggcattcata
    21541 tcatctgtca cctgaaggag aaagcaagaa accagctcac cacgacggct ccgtccagca
    21601 tttaaaaaag aaggagtagc aggttggtaa cgctgattaa tcatctcaat ggctaagtcc
    21661 ttagctaatg tttcatcacc atcagcaaaa taaagggcat tgaacatgac ccgatcctct
    21721 atgctctcta agtagaaatt gccatcattg gtttttaggg catactgctg ataaaattta
    21781 taggccgcca taaatgattt aaagcgaaag ccctctgctt gaatgctctt ggctagatgg
    21841 ctgataaatt caggagaata gttttggata aaggctgatt caatatagtc attgtctaca
    21901 agataggcaa tcttttcgtt gatagaagaa aatgacatgg tgttaggaat aacattttcg
    21961 gtaaaaaaag cctccaaagc ttccttgtct ttatgaagtg gaatgctgcc atcaacagga
    22021 cggttaattt cattgttgag gcgaaagtaa gaaatatcgc caagatcttt gagactcata
    22081 tcaattgttc cttgtctagt taaataatat cttttaattt tgctggctga aaccctgaga
    22141 atactatctg ctctgtctca ataacaggag cagcagtaaa gccaaggctc ttaacatagt
    22201 ccactttttc tggatgctca tcaatattaa tctcttggaa agcagctcca tgctgttcta
    22261 aaaatttctt agtcattttg cactgcatgc aattgtgctt tgagtatact gtaatcattg
    22321 ctcgtccttc caactattag tctttcactc aattttagga aaaatcaaat gactctaata
    22381 ggatataaaa aatgttccta aaaagcaaac gatttatttc agaatagcac aagatattgt
    22441 ggttgtgtgt gagaatattt ctaaatattg tgttatcctc tcttatcact gataattgct
    22501 acaagaggct tgtagttctt aaatgcatac taatcaggtt ggaaggctta tttgacatta
    22561 tgaaaatcat catgtaagaa atattgacaa caaatgaaaa tacaagaaaa ctgtttcatg
    22621 attttttctt gttagaacat ttaaccttga aaataaaaaa gcattgtgct ataatcactt
    22681 attgtaaggg ttatcatgtg atagctcgaa aatacacaat tcaaaaggag aaccatatta
    22741 tggcttcaaa agactttcac attgttgcag aaacaggtat tcatgcacgc ccagctacct
    22801 tacttattca aacagcaagc aaatttgctt cagatattac acttgactac aaaggtaaag
    22861 cagtaaatct taaatcaatc atgggtgtta tgagccttgg tgttggtcaa ggtgctgacg
    22921 taacaatcac agcagaaggc gctgatgcag atgacgctat tgcggcaatc gaagaaacta
    22981 tgactaaaga aggattggca taagactatg acagaaatgc ttaaaggaat cgcagcctct
    23041 gacggtgttg ctgttgccaa agcatatctg ctagttcagc cggatttgtc atttgagact
    23101 atcacagtcg aggatacaaa tgcagaagaa gctcgccttg atgttgcact acaagcttca
    23161 caagacgagc tttctgttat ccgagaaaaa gcagtagaaa gcctaggcga agaagcggca
    23221 gcagtttttg atgcccattt aatggttctt gctgatccag agatgatcag ccaaattaaa
    23281 gagactattc gtgcgaagca aacgaatgct gaaacaggtc taaaagaagt gactgacatg
    23341 ttcatcacaa tctttgaagg catggaagac aatccttata tgcaagagcg tgcggctgat
    23401 attcgagatg tcgctaagcg cgtcttggct catttattag gtgttaagct tccaaatcca
    23461 gctacaattg atgaagaagc aattgttatt gcacatgatt tgactccttc agatactgca
    23521 cagcttaaca aacaatttgt aaaagcattt gtaacgaaca ttggcggacg tacgagtcat
    23581 tcggctatca tggcccgtac acttgagatt gcggctgtgc ttggtacaaa tgatattact
    23641 aagcgtgtca aagatggtga ccttattgct gttaatggta tcactggtga ggttattatt
    23701 gacccaagtg aggagcagat tcttgctttc aaggaagctg gagaggctta tgcgaagcaa
    23761 aaggctgagt gggctctgct taaggacgca caaactgtca cagcagatgg caagtacttt
    23821 gaattagcag caaacatcgg tacacctaag gacgttgaag gtgtcaacga taatggtgct
    23881 gaggcggtag gtctttaccg tactgagttt ctttatatgg attctcagga tttcccaacc
    23941 gaagatgagc aatatgaagc ctacaaggct gttcttgaag gaatgaacgg caagcctgtt
    24001 gttgttcgta caatggatat cggtggggac aaggagcttc cttactttga tttaccaaag
    24061 gaaatgaacc cattccttgg ttttcgtgcc ttacgcattt caatctctga aacaggtaat
    24121 gctatgttcc gcacacaaat tcgtgctttg ctgcgtgctt ctgtgcatgg tcaattgcgt
    24181 atcatgttcc cgatggttgc ccttctaaag gaatttcgtg ctgctaaagt cgtatttgaa
    24241 gaagaaaagg ctagcttgct gtctgagggt gttgcggttg cagacgatat tcaggttggt
    24301 atcatgattg agatcccagc agcagcaatg cttgctgacc aatttgccaa ggaggttgac
    24361 ttcttctcaa ttggtacaaa tgaccttatc cagtacacaa tggcagcaga ccgcatgaac
    24421 gagcaagtgt cataccttta ccagccatat aacccatcaa tccttcgttt gattaacaat
    24481 gttatcaaag cagctcatgc tgaaggtaag tgggctggta tgtgtggtga aatggcaggt
    24541 gaccaacagg ctgtgccgct tcttgttggt atggggcttg atgaattttc aatgtcagca
    24601 acatctgtgc ttcgcacacg tagcctgatg aaaaagcttg attcagcgaa aatggcagag
    24661 tatgctcatc gtgcactcac agaatgctca actgctgaag aggttcttga gcttgccaaa
    24721 gagtatatta cagaagctta aatagaaata acgaggagct ggttttgtcc ggctcttttt
    24781 tactagaaaa atgactaatc agatccatat gaaagcttgc tttataaagt agtttgatgt
    24841 ttcaagtttt atcagaattt tcagactctt cctgtagcga attgttgaaa tatgctaaaa
    24901 aagtgataga ataatagtac cattataaaa ggagaaaaaa gtttggctaa acaatataaa
    24961 aatttagtga atggtgagtg gaagctctct gaaaatgaga tcaagatcta tgcaccagca
    25021 accggcgagg agttaggtag tgtaccagct atgtctcgtg aagaggttga tcaggtttat
    25081 gcgtcagctc gcgctgctct tgcagattgg agagcgcttt cttatgttga gcgtactgct
    25141 tatttgcaca aggctgctga tattttggtg cgtgatgctg agaagattgg tgctgttctc
    25201 tcaaaagagg ttgcaaaggg ttataaggct gctgttagtg aggttattcg tacagcagaa
    25261 attattaact atgcagcaga agaaggcctt cgtatggaag gcgaggtcct tgagggtggc
    25321 agctttgagg ctgctagtaa gaaaaagatt gcgatcgtac gtcgtgagcc agtgggactt
    25381 gtgcttgcga tttcaccctt caattatccg attaacctag caggctcaaa gattgctcca
    25441 gcccttattg caggaaatgt cgtggttctt aagccgccga cacaaggctc tatttctggc
    25501 ttgctcttag cagaggtatt tgcagaagca ggtcttcctg ctggagtctt taataccatc
    25561 actggacgcg gctcagttat tggtgattac atcgttgagc atgaggctgt aaactttatc
    25621 aactttactg gctcaacgcc aattggagag cgaattggta aattagccgg catgcgtccg
    25681 attatgcttg agcttggtgg taaggattca gcgattgtct tagaagatgc tgatattgcc
    25741 ttagctgcta aaaacattgt tgcaggtgcc tttggctact caggtcaacg ctgtacagca
    25801 gttaagcgtg tgcttgttat ggaaagcgtt gcagaccagc tggtagcaga gattaagggc
    25861 ttagttgaga aattacttat cggtatgcca gaggacaatg ctgacatcac accattgatt
    25921 gataccaaag cggcagattt tgttgaaggt ctggttaatg atgcagcaga caagggagca
    25981 caggcgctta ctgaaatcaa gcgtgacggt aatttaattt gtcctatctt gtttgataga
    26041 gtaacaactg atatgcgctt ggcttgggag gagccatttg gtccggtgct gccagtgatt
    26101 cgtgtaagct ctgtagaaga ggcaatcagc atttcaaatc aatctgaata cggtttgcaa
    26161 gcgtctatct ttacgactaa ttttccacag gcctttgcta ttgctgagaa gcttgaggtt
    26221 ggtacagtac acattaacaa caaaacccaa cgtggtacag ataatttccc attcctaggg
    26281 gctaagaaat caggagctgg tgttcaaggg gtcaaatatt caattgaggc aatgacaagt
    26341 ctcaaatcag tcgtatttga tattcaataa caaaaaagct agggtatctt agtttgaaag
    26401 cagttgcaca tttgtgcggc tgttttattt gtgtctctag ttttaacagc tagctatgca
    26461 agaaggtgag ttgtcccaac ctcaaagatg agatctaaat atttaatgat tttggggtcg
    26521 taaaaaagtt tagagtgttt tgatctcctt aagatgtgag tgtacaaagt ctcgccaaca
    26581 gccagcagga ctagccattg aggtcaagga agctgctaaa atagctgatg gttcaaaagc
    26641 ttggtgaaag gcttaatatc tatcattgct attttgaggg ctttccatta taatatgaat
    26701 actagagcta cttgtcggtc tgcctcttga gctgtgagat agctgttgga tttagttgtc
    26761 tccttgtcca caaaaggctt agaggcaaag gctgtggcta tgcttcttgc ttcttttagt
    26821 gaagtgtatg agatcttatg aaaactcata taggctttgg tatctttgca agaggactaa
    26881 tggcttgctt tacttgcctt gatagagggc tgggattgag gggtgatgac ctgcggtggt
    26941 catctctaga gctccttgct tcttttttta tgtagactaa tggtttagac tgctagcttc
    27001 cttgtttaga aagtaggaca tcatgttacc caagagaaaa ttaattgatc aacgtcttga
    27061 ttatgccatt atttttcctg ttttttgttt gctaatattt ggtctggtat ctgtatatgt
    27121 ggcagcaagt catgattttc cgcaaagcct cgccactgtt atgcttcaac aggttctctg
    27181 gatccttctt ggagctgtga ttgcctttac cctaatgttt tttagcacag agattctgtg
    27241 gaaattaaca cctgtctttt atcttttggg tgtgctatta atggttctgc cactcatctt
    27301 ttttagccct cggctggtag ctgctacagg ggcgaaaaat tggattacga ttggctcaac
    27361 gaccttgttt caaccatcag aatttatgaa aatatcctac attctggcaa tgtcttggtt
    27421 aacggtctgg tttaagagaa agcaggagag aagtcggttt ttagatgatt ggaagctctt
    27481 gggcttatac cttgtcttga cgttgccggt catggtcctg ctagcactgc aaaaggactt
    27541 aggaacagct atggtttttt tagccatctt agctgggatt atcttaattt caggaatttc
    27601 ttggtggctt attttaccag ctttggtact agtcttttta ctggtttcag cttttttctt
    27661 tgtttttttg ttgccagagg gaaaagaatt ccttttaaaa atgggaatgg atacctacca
    27721 attgaatcgt atttcagctt ggctgacacc gtttgatttc tcagatacca ttgcctatca
    27781 gcagacgcaa agtatgattt cgattgggag tggtggcttt tttggtaagg gctttaatca
    27841 gcttgagctg tcagtaccag tcagagaaag tgatatgatt tttacagtga tcgctgaaaa
    27901 ttttggcttt cttggtgcag ctagcttact gatcttgtat ttaatactga tttaccgcat
    27961 gcttagggtg acctttgcat cgaataacct tttttatacc tacatttcaa ccggctttat
    28021 catgatgata ctatttcata tttttgaaaa cattggcgca gcagttggtc tgctaccttt
    28081 gaccggtatt ccccttccct ttatttctca gggcggctct tccttgattt caaatctgat
    28141 tggggtcggc ctgatcctat caatgaacta tcagcacgtc cttgctcatg aaaagcaaag
    28201 cgagcatgag cttagcagaa gctcacgtta tgtttaagag gcatgtttgg tccttgttcg
    28261 gttagaatga gctgccaatc agcccttttt tatttgctta atcgctataa aaataaagaa
    28321 aaatatgtta taattaaggt tatgaattat catgattata tttgggattt gggcggcact
    28381 ctcttggata actatgaaat ttctacccag gcttttattg agacgctgca tttttttaag
    28441 ctgtctgcaa gccacgatgc cgtttatcaa aggcttaaga aatcaacagc aaccgccatt
    28501 caagtatttg ctcccaacga accgcaattt ttacaatatt acaaagcgaa tgaggctaag
    28561 aaattagcca atcctatttg gtgcctaggt gcaaaggaca ttctaaagag gattgtggca
    28621 tcaggctcgc gtaatttttt aatatcccat cgtgatcatc aggtcaatga tttgctggag
    28681 caggctgggc ttttgggcta ttttaccgag gttgttaccg cctcaaatgg ctttgccaga
    28741 aagcctaacc ctgagagctt actttatttg aaggaaaagt acctgatcag caagggctta
    28801 gtgattggtg atcgcagact tgatatagaa gcaggacaag cagcaggctt tgacaccctg
    28861 cttgttgatg gtagaaaaaa cctattggag atagtagatt agatggttga agaaaataaa
    28921 caattagaag acaaggctca agagtatgac gctagccaga ttcaggtctt agaggggtta
    28981 gaagccgttc gcatgcgtcc tggaatgtat attggctcaa ctgccaagga aggcttacat
    29041 cacctagttt gggagattgt tgataattct atcgatgaag ccttggcagg ctttgccagt
    29101 catattcagg tttttattga ggcagataat tcgattaccg ttattgatga tggacgtggt
    29161 atcccagttg atattcaagc taagacaggc cggcctgctg tagagacagt ttttacagtt
    29221 ttgcatgccg gtggaaaatt tggcggtggt ggctacaagg tttctggagg acttcatggt
    29281 gttggctcct cggttgttaa tgccttatcc acacagcttg atgttcgtgt ctataaaaat
    29341 gggcatatcc actatcagga gtttaggcgt ggtgctgtag ttgatgattt ggctatcatt
    29401 ggaacgactg atgttacggg aacaacagtg catttcacac ctgatccaga gatctttaca
    29461 gaaacaacag aatttgacta ccaggtcctg gcaaagcgta ttcaagagct ggcctttctt
    29521 aatcgtggct taaaaatctc aattacagat aaacgagctg gtcttgaaag agaagagcat
    29581 ttccattacg agggtggtat tggctcttat gttgcctttt taaatgacaa aaaggacgtc
    29641 atcttcgata ctccgattta ttctgatggt gagctggagg ggataacagt tgaggtggcg
    29701 atgcagtaca ctacaggtta ccatgagact gttatgagct ttgccaacaa tattcacaca
    29761 catgagggtg gtacccatga gcagggcttt agaacagctc tgacgcgcgt gattaatgac
    29821 tatgctaaga aggctaagat tctcaaggaa aacgaggata atctgacagg tgaggacgtc
    29881 cgcgagggct tgactgctgt tatttctgtc aagcacccaa atccacaatt tgaagggcaa
    29941 acaaagacaa agttaggaaa ttctgaggtt gttaagatta ccaatcgctt gtttagcgaa
    30001 gctcttcagc gctttctact agagaatccg caggttgccc gtaagattgt tgaaaagggg
    30061 attctagcct ctaaggctcg cattgctgcc aagagagcgc gtgaagtaac ccgcaaaaaa
    30121 tcaggcctag agatttccaa tttgccaggg aagctggctg actgctcctc aaatgatgct
    30181 agtcaaaatg agctttttat cgtggagggg gattcggctg gtggatcagc gaagtcaggt
    30241 cgcaatcgtg agtttcaggc tattctgcct attcgtggta aaattttaaa cgttgaaaaa
    30301 gcaacgatgg ataaaatcct tgctaacgaa gaaatcagaa gcctctttac tgctatgggg
    30361 acaggctttg gagcggagtt tgatgtttct agagctcgct atcaaaagct ggtcatcatg
    30421 actgatgcag atgtcgatgg agctcatatc agaacgcttt tgttaacgtt gatttatcgc
    30481 ttcatgcgac cagtattaga ggctggctat gtttacattg ctcagccacc gatttatggt
    30541 gttaaggttg gcagcgagat taaggaatac attcaaccgg gagtcaacca agaagaggag
    30601 ctaaaggctg ctcttgaaag acatagcaca ggacgctcaa ggccgactat tcaacgctat
    30661 aagggcctag gagagatgga cgatcaccag ctttgggaaa caacaatgga ccctgataat
    30721 cgtctaatgg cacgtgtgac cgtagatgat gcggcagagg ctgatcggat ttttgacatg
    30781 ctgatgggcg atcgtgttga gccaaggcgt gaatttattg aggaaaatgc ggtctatagt
    30841 acgcttgaca tttagtcaaa tatattttga aaagcaccta aaagtatgtt ataatcgtaa
    30901 cgttatagtg tatttttgat aatataataa aaggcgattc ttgctagttg ttcctactga
    30961 accggcagtt gatcaatcgc atctaaataa taaggagatt aagatgtcaa gcggaattat
    31021 cttgctgatt gtggccatag tcttactagt gattattgct tatttagtgg gtgttattat
    31081 acgcaagcgt aatgacacat taattaccag tctagaagaa cgaaaacaag ctttatttgg
    31141 ccttcctgtt aatgacgaaa tcgaggaagt caagtctctt cacttgattg gtcaaagcca
    31201 gacctcattt cgtgaatgga atcaaaagtg ggttgatttg accctaaata cctttaccga
    31261 tattgaaaag catatctttg aggctgagca cttaaatgac acctttaatt tcattcgtgc
    31321 caagcatgag attaatagcg ttgagagtca attgaatctc gttgaagagg atattaccgc
    31381 tattcgtgaa gcacttggca tattaaagga gcaggaagaa aaaaacagcg cgcgtgttac
    31441 tcatgcacta gatttgtacg aaaagttgca ggcttccgtt gctgaaaatg aagataattt
    31501 cggatcaaca atggccgaaa ttgaaaagca aatgaagaat attgaagcag agttttcaca
    31561 atttgttgcc cttaattcat caggtgaccc tgttgaagca gcggaggttt tggataaggc
    31621 tgaggagcat acgattgcct tggggcaaat tacagagcag atccctgcta ttgtagcaaa
    31681 gcttgaagat gattttccgg atcaattgga cgatctggag acaggctatc gtcgtttgct
    31741 ggaggaaaat tatcacttcc cagaaaaaaa tattgaagcc cgctttcaag agattcgtga
    31801 gtctattcgt gccaattcat cagagctggt tacccttgat ttggaccgag ctagagatga
    31861 aaatactcac attcaagagc gtatcgactc actgtatgag ctctttgagc gtgagattgc
    31921 agcctacaag gtggttgcta aaaatagcaa aatattacca agatacctgg ctcacgccaa
    31981 gcacaacaac gagcagttga agcatgagat tgctcgtcta tcacgtaagt atatcttgag
    32041 tgaaaatgaa ggcttaaata tcaaggcctt tgacaaagac ctcaaagata tcgaagacaa
    32101 tgtccttgag attgctgaag cctttgatca gcaggaaaag ccattttcag agctacagct
    32161 gattcttgat cgtagtatca agacgttggc ttctgtagag tctggtcaga tggacgtctt
    32221 tgctgctgtt aaagacattg aaaagattga gtcacaggct cgccagcact tagaaatcta
    32281 cgtcacacag cttcacatga ttaagcgtta tatggaaaag cgcaatttac cgggaattcc
    32341 acaggatttt ctgagtacct tctttaccac tagttcgcag ctagaagcat tgatggacga
    32401 actaagtaga ggacgtatca acattgaagc ggtgtcccgt ctgtctgagg tggcaacagc
    32461 tgctattgct aatctagaag agctaaccta ccaagtggtt cagcatgcta ccttgacaga
    32521 gcagctgctc cagtactcta accgttatcg ttcctttgaa gctggcgtgc aaaatagctt
    32581 tgagcatgcc ttgaaattgt tcgaggtgga caatgactat caggcatcat ttgatgagat
    32641 ttcctatgcc ttggagacag tcgagccagg agtgacagag cgttttgtca attcctatga
    32701 gaagacacgt gaacgtatcc gcttctaatg tgacaagggt tgatacttta tattacgaaa
    32761 aagcttgaaa aagcagtcca tgctgggcta tgctttttca agctttttga atggtcaggc
    32821 tatggcctcc ttgagctata cccaaaaagc tggttcaagc cagtcagtag agatagacaa
    32881 ggccttagtg ctattgggct gttgctacat gagatatttt gtaataaaat cagacgatta
    32941 tccatttaat taaaaaaaaa aaaaaaacga aactgcggag gaaacctgac gagtaactat
    33001 ttatggctat caatcagcat gttacactct ttttggaagg cctagcaatc actgactgtg
    33061 aggttaacca aagaaaataa gatgttaagg agaatatcaa tgaaaataac taaagcattg
    33121 tgtgtagcag gtgctgttgc agtcctagcc ttggcaccaa tcagctcaag tcctgcacca
    33181 acacagactg tatttgctgc tacacgtggt actgaagagt actgtcataa tgggtggtgc
    33241 agttttcttg atgaacatgg tgagtggaac acgaaacgtg agggcgaatc taatagtccc
    33301 ctacagcgag gttcatggtg ggattggatt tcttattggt ctggttatat atggtattct
    33361 gtatataact ggtttaggta acctctcaac gccactgcta ccatactgat aaatccctta
    33421 gactattcta agggattttt actgcaaaaa gcacataggg acaaggcaat acaagctcca
    33481 gcctgttctt agctccctat accggtaagg atcataacac tcagaactcc ggcagatgat
    33541 tgcaggagct attggagagt gaggactagt gaaagagcct ctgccagagg gatttgccct
    33601 tagtctttgt ttgttcagca ggcttattgt cagagggctt gtctagtata gccttgagat
    33661 tggtttcctc tttggtgatg gcatgatcac tatgaatgat cagagcaaaa ggagagacag
    33721 ctcctttctc atctacaata gtggcagata gagcgttttg ttgggccaat ttcatatagt
    33781 acatttgata agcagagccg aattcagagg ataatttgaa tgacaagggg aaataagcct
    33841 ctttgaggtg aggcagctgg gctgtgatgt agcctttagc cttttcatga tcaacctctg
    33901 tcaagggaag cgctaagaca atcctttcag cataggtccc taaataatag cgttgttggt
    33961 cggggtcaaa tcggttttct cctgaagctc cctttaagag tcttgtatct aatgaatcca
    34021 tacaatcctt tcaagcatgt gatactgtca ttatactatt aactgcgcca aataccaatg
    34081 ataaagcatt tactaggtat ttgatcggct tttggaagaa gatgaaatca aagaaaaaca
    34141 gcatgaaaac aactctctta tttcatgaaa ttagttttta agttgcttaa gaccctagtt
    34201 tgtggtatta ttaacatgta aaatattaaa actcataagg agagtattat aatgtcaatt
    34261 attactgatg tttacgctcg cgaagtcctt gactcacgcg gtaacccaac acttgaagtg
    34321 gaagtttata ctgaatcagg tgctttcgga cgtggtatgg ttccttcagg agcttctact
    34381 ggtgagcatg aagcagtaga acttcgtgat ggcgacaaat ctcgttacct tggtcttggt
    34441 actcaaaagg cagttgacaa cgttaacaac attatcgctg aagcgatcat tggttatgat
    34501 gttcgcgatc aacaagctat tgacagagcc atgatcgctc ttgacggtac tccaaacaaa
    34561 ggtaagcttg gtgctaatgc tattcttggt gtgtctatcg ctgtagcgcg tgctgctgct
    34621 gactaccttg aggtgccact ttacacttac cttggaggat tcaatactaa ggttcttcca
    34681 actcctatga tgaatattat caacggtggt tctcactcag acgctccaat tgctttccaa
    34741 gagttcatga ttatgccagt tggtgcacct accttcaaag aaggtcttcg ttggggtgct
    34801 gaggtattcc atgctcttaa gaaaatcctt aaagcgcgtg gacttgttac tgctgttggt
    34861 gacgaaggtg gatttgctcc taaatttgaa ggaactgaag atggtgtaga aacaatcctt
    34921 aaggctatcg aagctgctgg ctatgaagct ggtgaaaatg gtatcatgat tggttttgac
    34981 tgtgcgtcat cagaattcta cgataaagag cgcaaagtct acgactacac taagtttgaa
    35041 ggtgaaggcg ctgctgttcg tacatctgca gagcaaattg actaccttga agaattggtt
    35101 aacaaatacc caattatcac aatcgaagac ggtatggacg aaaatgactg ggaaggctgg
    35161 aaagcactta ctgagcgcct aggcaaacgt gttcaattgg ttggtgatga cttcttcgtt
    35221 acaaacactg aataccttgc tcgtggtatc aaagaaggtg cagctaactc aatccttatc
    35281 aaggttaacc aaatcggtac tttgactgaa acctttgaag ctatcgaaat ggctaaggaa
    35341 gctggctaca ctgctgttgt atcacaccgc tcaggtgaaa ctgaagattc aacaatcgct
    35401 gacatcgcag tggcaacaaa cgctggccaa atcaaaacag gttcattgtc acgtactgac
    35461 cgtatcgcta aatacaacca attgcttcgc atcgaagatc aacttggtga agttgcacaa
    35521 tacaaaggga tcaaatcatt ctacaacctt aaaaaataat ttgattttag attaaaaggt
    35581 tgacaagcct tgattttaaa gcattctagg actgtcctag agtgctttta gttttagctt
    35641 catgtcaact gtagtgggtg actgatagct aagcacgaga ggagacgaag gtcgccttct
    35701 ctttttcaat cggataaggc tagggaatcc ccaaatgtcg atgaagggaa ttttagaagg
    35761 tttctggaag tcgtatatga tttgtttccc tttgcagtgt ctacacctag gagactgata
    35821 gtccagtgta gcgctgactt cgatatgagt atcgtgctgg atagtcttat tcaaggtgat
    35881 attttgatct ttgattccga tgagtagtgt ggtatgatga atctgttcca taagacactt
    35941 tctaatgatg gtctggtcgc ttttcatgat aagccttatg gaactttttg ggtactcaaa
    36001 aagccctata atcttcataa tgaatttacc cattacagaa attatagagc caatatttag
    36061 aggattttag cctattggta gattgacagt ttcttaagat tgtgttacaa tgtaacacaa
    36121 agaaacgagg taaacgacta tgagtacagt tactatcaga ttaaatcaag aagaagaaat
    36181 atttttcaaa agttacgccc aactcacagg gcaaagttta tcaagtctat ttaaaaaagc
    36241 ccttgagcgg gatattgaag atgagtatga tttaaaaatc tatcatcaag cctatgctga
    36301 atataaagca gaccctgaga caattagcca tgctgatttt aagaaagagc taggcttata
    36361 acatgtaccg tatagagtat tctaaaaagg ctcaaaagca gattaagaaa gtagataagc
    36421 aaattcagag gttgctattt gcttggattg ataagtattt agagggaaca gataacccac
    36481 gcgcaaatgg caaaggtttg accggaaatc atgctaatga gtggcgttat cgtattggtg
    36541 attataggct tatttgtgat attcaagatg ataagatggt tgttttagcg cttgagtttg
    36601 ggcatcgtaa agatatttac taacgttgag gaagtaagat ggtcaaaaat aatgcaattg
    36661 gtagcaactg gaaagatgta agagctgagt tattcagcaa ggaagaattt tagaaagtga
    36721 tgctcgtatt gctattatgg acaagtatag ttaaaaagtg tgcgttttta atctgtatga
    36781 tgaagtaatt gataaagtaa caggtcaaaa ggctatcatt gtctgtattg ctaataaatt
    36841 ggtagatgat tgttatttaa tcgaaccgct aaaccattct tacttaccag attggcgtga
    36901 gataaatcag ttaattcgat ataaaaatta gcaccttatc gggtgctaat tccttgcctg
    36961 ctgaactcat aatttaatac cttttttact accccatatg tttcccctaa ttatgtgtac
    37021 ttgctagata taaggttaat tgggatagaa ttttgaataa agttgttgta ttttgtaata
    37081 gtgattgata ttgggataac cttaaaaaaa taatttgatt ttagattaaa aggtttacaa
    37141 gctttgattt taaagcattc taggactgtc ctagaatgct tttagttttg ataagcacaa
    37201 tccgctgttg actgtataaa ccgtatatga tacaaaataa gagcttgtag cagtgaagcc
    37261 actaactcta gtgctgtggg ctcaaccttg attgatgaat cccttgcttt taatgcgttt
    37321 atgaagcagt ggcgtatcag tctagctcgt tgtggaaagc aattaactag agaagaatta
    37381 ctatcctcaa tcaatatgct gacagccgca gggatttgtg agtttgattt gctgtggcag
    37441 cgtcttgctc ctaaggggtg tcagcgtccc aaatggagcc atcagctgga gaggctcttt
    37501 gcggatacaa agccttgtct acaggtcttg tctgagactt atcagcttgg gattattgct
    37561 aatcaggcaa agggtctaaa agagcgctta gagaggtttg ggattagtca ttattttgcc
    37621 cttatgatat cttcttctga tgtggggcta caaaagcctg atcttgctct gtttcgctat
    37681 gcacttgatc aagcaggcgt attagcgcgt gatgctgttt atattgggga tcgtgttgac
    37741 aatgatatta ttcctgctaa ggcattggga atgagagctg tcaggattca tcaagggctt
    37801 gctgcgtcca gtccagatga taggctttat cctagtgatg tccatattag caaacttagt
    37861 gacctgttag aatgctttta accagtcttt agcttgaact agcttttctt tgtggtcttt
    37921 ctgggtgaat ggcagcaagc tttggagtca tgttatggct agaccttgga tctaagggcg
    37981 ctgagcgtct catatgatga ggccgatcaa gtagtctcct tgacaagtag attattgttt
    38041 ggtgcttata ggtggcttta ggtgatgact ggttttgcct caactaaggc tcgctattgc
    38101 tatctggggt atcttctgac ttttttaatg tgctcttatc tggttggatt agacctgctc
    38161 cttgcttgag gaaagctgtt tttaacgctg atgagtctgg gaaatggtga gattggtgtt
    38221 ggcttttact agtttttttg cgtttacttg ggctaacttt atatgagaaa aaaagaaaaa
    38281 tatttatttt atctgttatt tttgttacaa taagcgtgta aactaagatg cattaaaaag
    38341 gagtttttat gtcgaataag aaatttttta cttatgcttc attattggca ttaatcgctg
    38401 ttcctactgt ggttgaagag gtgactgcac agccttcagc tcagcttgtt tatgcagatg
    38461 agctaaggct atcaccaagt accgactcat ctccagtaac aaagaccgat gaggctgatc
    38521 agccagttgc tcaatctgtt tctgcgacag aaccagtaga ggctcttgtt attgcggata
    38581 aagaaagcgc tttaaatcct gctgttctag ctgatgccga tggaagtcag ccgattgcag
    38641 tggttagagc tggtcaagag ggtcagcctt ataccgttac tggcaaaatc atcagtgctg
    38701 ttaatggctg gggtggtcat ggcttttata tccaggacag tcagggatca ggtctttaca
    38761 tttatccagg aagtgctttg gggtacgtga ctggtgatgt ggtgcagctg acaggaacac
    38821 tgactactta caagggtgag cttcagctta aaacgattac aaagcatcat aagattaatg
    38881 gcgaattacc aacacctatt gctgaggtaa ccattccgga gctagaaaaa gcaagcccgt
    38941 ctaccctggt gaagctttca aatgtgactg ttggagacat ttcatcagat aagcacgaaa
    39001 cctcctcttt taaggtcagc gatacagctg gcaatagtgt tgcggtgcgt cttgataatc
    39061 gtacaggtgt taagacctct gacttactct ctaaaattgg caagggtgat gtgattaatc
    39121 tgacagctat tcactcaacc tttgatggga agctccagct caagcccttt agccttgagc
    39181 aatttgaggt agtaaagaag gttgttcgag aagaagaggt gactcctctt ggtcgagtgg
    39241 ttaaaatcgg ccaaattcaa ggtgccagcc acacctcacc gctcttgaat caagctgtaa
    39301 cagtaaaaga ggtggtggtg acctatcctg atgatgcaac tcatttctat gtgcaagata
    39361 ttaatggtga caacgataag gcgacctcag acggtattcg tgtctttgct caaaatgctc
    39421 aggtgcaggc tggtgatgtg ctgaccattt ccggaacagt ggaggagttc tttggcaaag
    39481 gctacgatga ccgtaagcag acggatctga ccattacgca aatcaaggca tctaaggtca
    39541 ctaaaacagg gactgctcag gtaccagctc cgcttgtgct aggtaaggat cgtgttgctc
    39601 cagctaatat cattgataat gatggcttta gtgtttttga tccagaagag gacgctattg
    39661 atttttggga atccttggag ggaatgcttg ttgccgttga taatgccaag attttagggc
    39721 cgatgtctca taaggaaatt tatgtgttac cagggtcatc aactcgagtg ctgactaact
    39781 caggtggtat tttacttcct gagacaggct ataatacaga cctgattcct gttctcttta
    39841 aaaaaggaaa gcaaaccatc aaagctggtg attcctatca gggacgactt gcaggtccgg
    39901 tatcatatag ctatggtaat tataaggtgt ttgtcgatga cagcagtcgt atgccagtct
    39961 tggttgatgg tcagctgaag cctgaaaaga cacacatcaa gaaggacctt agcaagctaa
    40021 gcattgcctc atacaacatt gaaaacttct cagcaaaccc atcatcaaca aaagacgaga
    40081 aggtaaggcg cattgcagaa tccttcatct atgacctaaa tgctcctgat attattggtc
    40141 tcatcgaggt tcaggacaat aatggaccta ctgatgatgg cacaacagat gcaacacaaa
    40201 gcgctcagcg cttgattgat gccatcaagg ccttaggtgg accagcttat caatatgtgg
    40261 atattgctcc ggaaaataac gctgatggtg ggcagccggg cagtaatatt cggacaggct
    40321 tcctgtatca gccaggacgt gtcagccttt ctgataagcc tagaggtggt gttaatgatg
    40381 cggtgaaatg ggtaaatggt gagctaagct tgagtgttgg acgtattgac ccaacaaatc
    40441 ctgcttggaa tagtgttaga aaatcattgg ctgctgagtt tattttccaa ggccacaagg
    40501 ttgtggtggt tgccaatcat ttgaattcca aacgaggcga caattcatta tatggacgtg
    40561 ttcagccggt aacctttaaa tcagaggaaa gacgtcatgt cttagcaagg cttttgagcc
    40621 aatttactaa ggaaggtgct agtcagcagg ctaatatcgt tatgttgggt gactttaacg
    40681 attatgagtt tacgaagacc attaagctga ttgaagaagg agatatggca aatttggtga
    40741 gcaggcatga gctttctgac cgttattctt acttctatag aggaaataac caaacgcttg
    40801 ataacatgct tgtttcacgc aatttgcttg gtcgctacga gtttgacatg gttcatgtga
    40861 attcaccatt tatggaagcg catggacgtg cttctgatca tgatccgttg cttcttcagc
    40921 tctcctttgg aaaagacaag ccagcagcac catcagatca gccaaagaaa acaccagcac
    40981 cagctgcgac aactcaagcc tctaaggcag gacgtgcaca gctattgcca aaaacaggtg
    41041 ataagacagc gcttatggta agtattttag gcttaacagc tgtctttagc tcctttagcc
    41101 tgtttaggaa atgtcaggaa aggaagtaaa ggatttcttt ggggtaggcc agcagctgag
    41161 cggctactgc gttttgtctg ctggtgctat ataggtggtt gaagcgagcg aagagaggta
    41221 tgcttcctag gatcatagca caatatctta tgcttataaa cgaacacaat gctccttatg
    41281 agcattcaaa acctatactc aaaaggaata taacagctga gttaagaggg attgcttttg
    41341 acagattgtg gtaaaaaaag ggatcttgag gaattggcta gtgatctagc tgccaaaatg
    41401 cgatgtcttg tttgactatt tttccctatt gggatataat gacaatagaa aaagggtagt
    41461 tgtttgcgca actaccctgt gcagaaccgt ttaagacggt ggcagaatga aagttaaaaa
    41521 ataatcgtcg acctaccaaa gttcagacgg ttatttttta ttgtttaata tgacgattgc
    41581 aacgactaag ctgattaagg taagtaagaa actaccaaaa gccagcatga gttgaagggc
    41641 ctcgtaagta gacaataaaa cgctcctttc agttggattt tgatgcattg cccataggca
    41701 tcaccacctt tcagaaatca gagccaccgt cttagctttt ctgtaaagaa cattatatca
    41761 taatcacatg agaaagccgt tagattttaa actgatcagg cggctttttg gtgttttgct
    41821 gtcttttagt ggaatcgcct aagctttgct gtatagtatg ggattttatg ctttttgtaa
    41881 gggcttaggc tgctatggca gggtccatgt cctttgtcaa tagcttagtt ttatggtaca
    41941 atgtaggcgt tgcctagcaa cccttggtgc ttagttccct ttcaccaagc atattacaaa
    42001 cgtggcggag ctgtttatgc tctagtctga cgtcaaagga gaaacacatg acaagtttta
    42061 ctgttcgtga ctatgtttac attgctctag tggctgccct ttatgtggtt ttgacaatca
    42121 ctccaccttt gaatgctatt tcctatggca tgtatcaatt tcgggttgcc gagatgatga
    42181 attttttggc tttttaccat aaaaagtata tcattgcggt gaccttgggc tgtatgattg
    42241 ctaattttta tagctttggc ttgattgatg ttttggtggg tggaggctca acgctcattt
    42301 ttgttagctt aggtgtcgct ttatttaagc aataccaaga ggaatatctc ttaaatggct
    42361 tgctgaataa ggcctttgtt tatttctcac tattttttgc gacttctatg atcaccgttg
    42421 cgattgagct ttacttcttt ggagcaccat ttttcctaac ttggtttacc actgctgtag
    42481 gggaatttgc ttcacttatc attggctcta tgatcattga tcgcttatca aaacgcatta
    42541 atttacgaca ataatagtaa catgtagcct tccgtttttg ggaggctttt tatgattttc
    42601 ttctagctag gcaatagctt atttgctatg ttttgtgata aaataagact atgaaaaaac
    42661 gcataagaga attgactgat ctgttaaatc aataccgtca ggagtattac accaatgacg
    42721 ctccttctgt atctgatagt gagtatgata agctttatcg tgagcttgta gagctggagc
    42781 agacctatcc agcctatatc ctaaaggaca gccccacaca gctggtgggc agtacgattt
    42841 tgacaggatt tcagaaatat cagcaccagt atccgctctt tagtttgcag gatgcttttt
    42901 cacgtgaaga gcttaacgcc tttgatcagc ggatcaaatc agcctttcct gaggctgaat
    42961 accttgctga gctaaaaatt gatggcttgt ccatttcgct ggtttatgag gctggtgttc
    43021 taaaggttgg agcgacacgt ggcgatggga ctattggcga gaatatcact gaaaacatta
    43081 agaatattaa ggatattccc aaacggctaa gtcaagcact tgatgtgacg atacgggggg
    43141 aggcctatat gtcgcgtcag gcctttaaga cgatcaatga agagcgtcag gaaaatggtg
    43201 agccagaatt tgccaatcca agaaatgcag cggcaggaac cttgaggcag ctggatacta
    43261 ggattgttgc caagcgacag ctagcaacct ttttgtatca ggaggtaggc ctagaaactg
    43321 ctgatagcca gcaaaagacc ttggagcgct tggccgattt aggcttttcg gtcaatagcc
    43381 actatctgct gtcctcatcg atgaatgaca tttgggactt tatccagagc attgaagcta
    43441 gtagagaaga gctaccttat gagattgatg gtgtggtggt caaggttaat cagttggcga
    43501 tccaagagga acttggcttt accgtcaagg caccacgctg ggctattgct tataagtttc
    43561 cagcagaaga aaaggaagct gagattgtat ctgtggattg gacggttggc cgaacaggtg
    43621 tggtcacacc aacagctaat ttgacccctg tgcagctggc aggcaccact gtcagtcgag
    43681 cgaccttgca taatgttgat tatatcgcag aaaaggatat tcgcattggg gatacggtgg
    43741 tggtgtataa ggctggagat attattccag ctgttttgcg ggtggttgag gctaagcgta
    43801 gggatcaggc tccaatgccc attcctacag cctgtccttc ctgccagagt cagctggtgc
    43861 attttgagga cgaggtagct ttgcgttgca ttaacccctt gtgtccgagc ttggttcaac
    43921 ggagcttgga gcattttgcc agtcgtcagg cgatgaatat cgctggtctt ggtccagcgg
    43981 ttgttgaaaa gctttattct gctggcctgg tgcatgatgt ggcagatatt taccgactaa
    44041 gcttggagga tttgctgacg ctagatggta tcaaggaaaa gtcggctgaa aagctcttgg
    44101 cagctattga acaatcaaag gcaaactcag ctgaaaagct cttgtttgga cttggtattc
    44161 gtcatattgg cgcaaaggct agtcgtctga tattagaggc ttacggtgat ttagaggcgc
    44221 tgttagctgt aaccgctgaa gagctcgctc agattgacgg gcttggtcta gtgatcggac
    44281 aatccctggt gcagtatttt cagcaagagc aagccgctca gctgctagct gaattaaaat
    44341 cagctggggt taatctggct tatttaggcc aaaggcctga tcaacaggct gcgctgtttg
    44401 gtttaacggt ggtattgaca ggaaaattag aaaagctaaa ccgtacccaa gccatggaaa
    44461 agctagagca gcttggtgct aaggtaacag gaagcgtttc taaaaaaaca gatttagtgg
    44521 ttgctggcag cgaggcaggc tctaagctgg ctaaggccca gcagctgggt atcagaattg
    44581 aagatgagga ttggttgctc aatctttagt gaggtaataa catgaaaaaa caaatgaggg
    44641 ctcgtctgat ttacaatcca acctctggtc aagaaatcat gaaaaaaaac gttgcagagg
    44701 tgctggatat tttggaaggc tttggctatg aaacctctgc ctttcaaacg acagcagcta
    44761 agcactcagc cttaaaggaa gcaagaaggg cagctaaagc aggctttgac ctcttgattg
    44821 ctgctggtgg agatggtacg atcaacgaag tagtcaatgg cattgctccc ctagagaaaa
    44881 gacctaagat ggcgattatt ccagcaggaa ccaccaatga ttttgctagg gccttaaagg
    44941 taccaagagg caatcccgtt gaggccgcta agctgattgg taaaaatcaa accatccgca
    45001 tggatatagg acgtgctaaa aaggatactt attttatcaa catttcagcc gcaggaagcc
    45061 tgacagagct gacctatagt gtccctagtc agctcaaaac catgtttggc tacctggctt
    45121 atctggctaa gggagtggag ctcttgcctc gagtgagtaa tgttccggtg aaaatcacgc
    45181 atgatcatgg catttttgag ggagaggtat caatgatttt tgcagccatc actaattctg
    45241 ttggtggctt tgaaaagatt gccccagatg ctaagctaga tgatggcatg tttaccctta
    45301 ttttgattaa aacagccaac ctgtttgaaa ttgtgcacct gctgcggttg atcattgacg
    45361 gtggtaagca tgttacggat cgccgcgtcg aatacattaa aaccagtaaa atcaccattg
    45421 agccccaatc agataagcgc atgatgatta atttagatgg tgaatatggt ggtgatgcgc
    45481 caattaccct agaaaactta aaaaatcaca tcaccttttt tgcaaatact gatttgattt
    45541 cagatgatgc ccttgtccta gaccaagagg agctggaaat cgaagaaatg gtcaagaaat
    45601 ttgcgcatga ggtagaggat ttagagcagg gattggagga atagggctag ttatggataa
    45661 tgcagttatt gttcattatc atagttgcaa gggacattat tttcaattaa gtctatggca
    45721 atggcgagat ggtaagctgg gcaaggacgc ttatttttcg aggtttgaca gctttggagc
    45781 agttgcttat ctcacttatc cagcacctta ttttttgagt catgcttatg tgattgtaaa
    45841 ggatcagttt tggcagcatc aaaccgttga ttttcggatt gagcgtgatt atggggttcc
    45901 aaagactgag gtgtggcttg ttgatggtga tcctacggtt tattattcga gacaggctgc
    45961 tgtggctagt cgacatgatg gtagatgtga tgtgcatgcc tttgatatgg ctgtcaatag
    46021 tcaggccttt gacaagcgct ggggctttag tggctggcta ggctttcgct atcagcctga
    46081 ggagacgtct tttcgtttgt gggctccaac agcagaaaag gttgagctca ttctctatgc
    46141 ttcgactgat gagagagcta gtgttgccaa ggttttgccc atgcagcgtg ggcagcagta
    46201 ctcgccagat catcatgcag aaaacacatg tggtgtgtgg gacatcagcc taagaggtga
    46261 ttataattac catgcttatt gctaccgggt ttattatcgc aggcgtacct ttagagacac
    46321 tagggatcct tatgcgatcg caacgacagc aaatggcaaa aggtcaattg tcattgcacc
    46381 ggagcattta agaccgcagg gcttttcagt gaagcagggt aaggaggcta cctggcgctt
    46441 agacaatcct aatcaggcgg tgatctatga aatgcatgtt cgcgactttt caaaatcaga
    46501 aacctcgggc gttagcttgg ctaatcgtgg caaatttaag gggctgattg agacaggcac
    46561 gcgcaatgct tttggagatt caacctgctt tgattatgtc aagtcccttg gcattacgca
    46621 tattcagctc cagccggtct ttgaccatca tcaattcttt gatgaaaatg gagattatgc
    46681 ctataattgg ggctatgacc ctgaaaatta caatgttcca gcagccagct ttaccagtaa
    46741 tccgcatgag ccagctaccc gtatcctgga attaaaggag gtcattcagg cttatcatga
    46801 tgcaggcatc aatgtgatca tggacgtggt gtacaatcat acctactcat caagagagtc
    46861 agcctttcag ctgacggttc cggattatta ttaccgtatg aatcctaatg gctcctttca
    46921 aaatggctct ggctgtggca atgaaacggc tagtgaaaag gaaatgtatc gcaaatacat
    46981 gcttgattcg atcctatatt ggaccaatga gtttaacatt gatggcttca ggtttgatct
    47041 gatgggctta cacgatattg acaccatgaa tcttatccga caagagctag ataagattga
    47101 cccaaggata cttgtttttg gtgagggctg ggatatggga gttggtctgg cagctgagca
    47161 gaaggctaaa aaaggaaatg ccagccaaat gcctggaatc ggctttatta atgatgatca
    47221 gcgtaatgca gttaaggggg cagaggtcta tgggagctta gagaagggct ttgtatcagg
    47281 tgcaccgaca gaaggacttg tagccaagtc tattttgggc agtgatgagc tggtctctta
    47341 ttgtacgcct agtcaggtga tcaattatgt tgaagctcat gacaactata acctcaatga
    47401 tttgctgtgg gttttgaatc cagaggacag caagcaggat catgtcaaac gggttcagct
    47461 agcttcagct atgacgattc tcatgcaagg gatttacttt atgcagctgg gtcaggaatt
    47521 tttacgaaca aagctttacc caacaggtca ggataaggag ctgacacagg cagaccgaga
    47581 aagggcgatg aattcctaca atgcacctga caatgtgaat caggttgact ggagacaggt
    47641 tagcttggag cgcgaaacgg ttgctattat gaaaaaacta atctatctga aaactaaaac
    47701 agctttgttt tcatacccat catttgagca aatcagacag catgtttaca ttgagcatgc
    47761 tggtgaaaat acgggcttca ttagctttac agtagaagat gaaagaaagt atcgattgat
    47821 tttctctagt tttagaaacc gcttgcaatc atctgctaat catgttataa ttgaaacaaa
    47881 tgataagcgc tttcaagata gtgagtccat gctagatgag ctgacagcga tgatccttga
    47941 catcacacaa tagcctgagt gttctcaggt tatttttgtt tgttgtcaag gataaaaggg
    48001 ctgtagttac agttagcaga gacctattag gaccttgctt atcatatcgc ttagcgcctt
    48061 gaaaaagggt ttaggagtag ggaaagaaga ggtgatggga tggataatga cttagcgctt
    48121 tatacctttg gcacaggtga gaattttcac atacaggatt atctaggtgt tcatcggatt
    48181 aacaatgaca caggcaccag ctatgtcttt agggtatggg cgcccaatgc agaggctgtc
    48241 agcttgattg gagattttac tgattggcag tccaatccac ttgagatgag ccgaaatgag
    48301 gctggcgtgt gggaggttac cactagcttg ccgcaggaag gagatattta taagtattgg
    48361 gttaggcgcc aaggtggtca gcttgttgaa aaaattgatc cagtggcctt tctatttgaa
    48421 gctagaccag gaacgggtgc tattgtcaaa acccttccag ccaaaaaatg gcgtgatagc
    48481 ttatggatgg gacggcgaaa gcgttttggc tttaggcagc gtccggttaa tatctatgag
    48541 gttcatgccc attcatggaa aaaagacgaa aacgcaaggc cctatgactt tagcaagcta
    48601 aaagaagagc tcattcccta tctcaagagc atgcactaca ctcatgttga gtttatgccg
    48661 gtcatggctc accccttaga tatgagctgg ggctatcagc tgatgggcta ctttgccttt
    48721 gagtcaacct ttggaagccc agaagccttt caggattttg ttgaggcctg tcatcttaat
    48781 aatattggtg ttttgattga ttgggtgccg ggacatttta cacaaaatga tgacgcctta
    48841 gcttattttg acggtacagc tacctatgaa tatcaggatc accatcgtgc tcataattat
    48901 ggctgggggc cctaaatttt gatttgggta aaactcaggt acagtccttt ttgatttcaa
    48961 gtgccctttt ttggctggag gcttatcatg ttgacggcat tcgagtagat gctgttagca
    49021 atatgcttta cttggattat gatcaaggcc cttggactcc gaatcaatac ggtggcaacc
    49081 aaaaccttga ggggatagcc tttcttcaaa aattaaccac agttatcaag gaaaaacacc
    49141 ctgatgtgat gatgattgca gaggaggcga cctcagctac cccaataacc agccctgttg
    49201 cagaaggggg actaggcttt gattataagt ggaatatggg ctggatgaat gatattctta
    49261 ggttttacga agaggatcct tattaccgaa aatacgattt caatctcttg acctttagct
    49321 ttatgtattg ctttaaggag cattacattt tacccttttc tcacgatgag gttgttcatg
    49381 gcaaaaaaag cctcatgcat aaaatgtggg gggaccgcta caatcaattt gcaggcctaa
    49441 gaaatcttta cacctatcaa atctgccacc caggcaagaa gctgcttttt atgggatctg
    49501 agtttggaca gtttttggaa tggaaatacg atcatcaatt agagtggcaa aatttagagg
    49561 acgagctcaa tgccaaaatg cagcatttca cagccagcct aaatcagcta tataaggacc
    49621 atagcatgct gtggcaaaat gatgaaacct atgacggcat tgatattatt gatgcagaca
    49681 ataaggacga atcagtcttg tcgttttgtc gtcaaaacaa taaaggagag ctcctgcttt
    49741 gtgtctttaa catgacacct gttgaaagac caggctttac cataggtgtg ccgatagcag
    49801 gtctttatca agaaattttc aatacagagc ttgaggcctt tggaggtgtc tggaaggagc
    49861 acaatccctt aaccaacaca gtagccaaga aatggaagac ttatccgcag accttgagct
    49921 ttaccctgcc tgcactagga gcaagcatct ggaaaatcaa gcgtcgtcag aagcaataag
    49981 ctattcattg cttacttagc tgtttcaacc aaaagaagtc actacagtca tgaaaggata
    50041 acgaaatgaa gaatggaatg ttagccctca tattagcagg gggacaagga actcgcttag
    50101 gaaaattgac acagagcatt gcaaagcctg ctgtgcaatt tggaggtcgg tatcgtatca
    50161 ttgattttgc cctatccaat tgtgctaact cagggattca taatgtgggg gttatcaccc
    50221 agtaccagcc tcttgcctta aataatcata ttggcaatgg ttcgtcatgg ggcttagatg
    50281 gtattaattc tggcgctacg attttacagc cctactctgc aacagaggga aatcgctggt
    50341 ttcaaggaac tagccatgct atctatcaaa atattgatta tattgatagc attaaccctg
    50401 aatatgtgct gatcctgtct ggtgatcata tttacaaaat ggactatgat gacatgcttc
    50461 agacgcataa ggctaatatg gctagcttga ctgttgctgt gattgatgtt cctctaaagg
    50521 aagccagtcg atttggcatt atgaacacag ataccaatga ccgcattgtc gaatttgaag
    50581 aaaagcctgc caatccaaaa tcaaccaagg cttcaatggg tatttatatc tttaattggc
    50641 agcgccttcg gaccatgctg gttgacgcag aaaaaaacaa cattgatatg tctgactttg
    50701 gtcagcatgt gattccgtct taccttgagt ctggcgagcg tgtctacacc tataacttta
    50761 aaggctactg gaaggacgtc ggaacgattg agtctctctg ggaagccaat atggaataca
    50821 tcggtgagga aaatgcccta gacagtcgtg atcgttcttg gaagatttat tctaaaaacc
    50881 atatcgctcc accaaacttt atcacagagg acgccgaggt caaggattct ctggtagtag
    50941 atggcagctt tatctctggt aaggtcaacc attctatctt gtctaccaat gtgcaggtaa
    51001 gaaagggagc cgaggttaag gattccttta tcatgagcga tgttatcatt ggtgagggtg
    51061 caaggattac acgagctatt attggtgagg gtgcagtcat tggtgatcat gtgatcattg
    51121 atggcagcaa ggacgttcaa gtcgtaggct ataatgaagt agtgggggta ccaaatgaag
    51181 attgataaat attctgccat tctaggcagc tcaattggct ttgctgaaat gaaggggcta
    51241 acagacacaa gaccattagc caacctaccc tttgatggga aataccggct cattgatttt
    51301 caattgtcca accttgccaa tgcaggtgtc cgtagcatct atggtatttt tcgtgggcaa
    51361 aatatccgct cagtgtttga tcatatcagg tcaggtcgtg aatgggggct taattcctta
    51421 ctaagtcatt atttccttgg cttttataac accaaggagg attctaaaga ggctgacaag
    51481 gactattatc agcagatttt gacctattta aagcgctcag ggtcagatca gaccatttac
    51541 atgagctgtg atattctctg caatattgag cttgggcagg ttattcatct gcacaatgcc
    51601 aaccatcgca acattacggt tgtctacaag aaaatgccga ccaaggccat ctctaaggct
    51661 aacgatattt tagatattga cgagacagat actgttgttg acaggcgaag tctgtctgag
    51721 gggcaggagg ttgaaaaaat gtcagcaggc atttacatcg tcaatacccc atggttaatt
    51781 gaacagatgg aaaaagaagc cgaaaaagaa aaccctcaaa agctacgctt cctcttacgt
    51841 gatttgattg tgtcagaggg cgctcttggc tttgaatata ctggctatct tgccaatatt
    51901 cactctgtta aatcttattt tgatgccaat atggacatgc tggatccgca taagttttat
    51961 tcactattat atgctaatca gaaggtctac acgcgtgtca aaaatgaaga gtcaacctat
    52021 tttgatgcgg cttctgaggt gaacaatgcc caatttgctt caggaagcat tgtcaagggc
    52081 tatgtcgagc actcaattgt ctctcgcaat tgtcgcatta cctcacaggc acgtgttaca
    52141 aatagtattt tattgccaaa ggcagtgatt ggtgagggtg ctgtcattga ttatgctatc
    52201 attgataaat ccgtaagggt tgcaccaggt gttactatta gaggaagcgc tgaggagcca
    52261 atagttgttg ccaaggggac tgaggttgtt gaggatatga taaaatgaag ataatgtttg
    52321 ttgcagcaga gggagctccc tttgctaaga caggtggcct aggcgatgtc attggggcat
    52381 tgcctaaatc acttgttaaa aatggtcatg aggtgtctgt gatactgcct tattatgacg
    52441 tggttgatca agcctttggt cagcaggttg aggacgtctt gtatttttat acgcaggttg
    52501 gctggagacg ccaatacgtg ggcattaaaa agcttgtcaa ggataaggtg accttttact
    52561 ttattgacaa tcaaggttat ttctttagag gcaggatcta tggtgattgg gacgacggtg
    52621 agcgctttgc ctatttccag ctggctgcca tagaagcaat ggagaaaatc ggggttattc
    52681 cagatatttt gcatgtgcat gattaccata ccgctatgat tcctttccta ttgaaagaaa
    52741 aataccattg gattcaggcc tatcaagcga ttcggacagt ttttaccatt cataatatcg
    52801 catttcaagg gcagtttgat cctggcatgc taggcgattt gtttgatgtt ggtatagagc
    52861 gctacgagga tggcaccctg cgttggcatg attgcttgaa ttggatgaaa gcagcagtcc
    52921 tatatgcaga tcgggtaacc actgtctcac cctcttatgc gcatgaaatt cagacaccag
    52981 cctttggaca aggcttggat caagtcatgc gaatggaggc aggcaagcta tcaggcattg
    53041 tgaatggtat tgacactgac ttatttaacc cagcaaggga tcctcatttg cctgcttcat
    53101 tttcagcaga agacctatca ggcaaggcgg ctactaaaca ggccttgcag gagcggttag
    53161 gattaccagt cagggcagat gttccattga ttggtatggt ttcgcgcttg acggatcaaa
    53221 agggctttca gcttgttctt gaggaattac cgcatatctt gcagcaggac gttcagcttg
    53281 tcttgttagg aacaggtgac cctgattatg aggctgcctt ttcatggttt gccaaggcct
    53341 atccagaaaa actgtctgct aatattacct ttgatctgcc attagctcag cagatttatg
    53401 gggcctgtga tctcttttta atgccaagtg cttttgagcc ctgcggactt tcgcaaatga
    53461 tggctatgag atatggcgcg ataccgattg tccatgagat cggcggcttg aaggatactg
    53521 ttgcctccta caatgcttat gaaaagactg gaactggttt tggctttgat cagttttcag
    53581 gattttggtt aacgcagacg ctcttgtttg cccttgatat ttaccataac cacaaggagg
    53641 attggcagac tattcaacaa catgccatga ccaaggattt ttcatgggat acagccagtc
    53701 tggcctacct tgatttatat aaaagcttac tataacacag aaaaggaatg ggaatgcacg
    53761 tcacaaaaga acaatttatt cgagatttta aagatacctt acatgaggaa caattgatca
    53821 aggttcctgc cgcaacagct gctgagcttt tcacctcatt agcaaagctt atccgtaaat
    53881 actatacaga tacttggatt gaaaggaatc gttccttaac cgaacagcag caaaaaattg
    53941 cctattattt ttcgatcgaa tttttaccag gaagaatgct agaaacaaat cttcttaatt
    54001 taggcattct tgatacagtt aaagaagcct ttgctgactt gggaattgat tttcaagcag
    54061 tgaagcatgc agagcacgac atggctctag gcaatggagg tctaggacgt ttggcagctg
    54121 cctttatgga ttcgctagcg acaacaggct atccaggctt tggaaatggg ctgcgttatc
    54181 gttatgggct gtttaagcaa cggattgtga atggttatca ggtagaatta ccagattctt
    54241 ggtttggctc tattggtaat gtctgggaga tcagaaagga tcatgacatt gtagacgtca
    54301 agctctttgg gaatgtttac ctaaaagcca atcaggacgg taagctagcg ccaatctatg
    54361 agggagctca ggttttgaga gctgttccct acgatgttcc tcagattggc tttgaaaatg
    54421 atgtgattaa caatcttcgc ctctgggacg tagaaatccc agaagaacat gagcttgatt
    54481 acccaaccat cgagtcaaga cgggcagtca aggacattac tgccattttg tacccagacg
    54541 acagcagcta tgaaggcaaa aagcttagat tgatccaaga atatttcatg accagcgcag
    54601 gcatccaaac cattatcaaa tcctatttaa agcagggctt gccacttact gagcttcatc
    54661 aaaaggtatc tgttcatatc aatgataccc acccagcagt agctccagca gagcttatgc
    54721 ggctcttgat tgacgactat ggcttagaat gggtagacgc ctgggcgaca accgtaaaaa
    54781 ccatgagcta taccaatcat acgattttgt cagaagcctt agaaaaatgg gacgcagagc
    54841 tctttaagac tgtgctgccc cgcgtttatc aaatcatttt agagattgat catcgctttg
    54901 ttgctgaaat ggcgcaaaag ggtattgatc ctcagatcat tgaaaacact agaatcgtta
    54961 aggacaacca gatttatatg gctaatcttg ccattattgg tggctattcg gtcaatggcg
    55021 ttgccaagct acatacagag ttgttaaaga cagataccct taaggacttt tatgccttgt
    55081 atcctgaaaa attcaacaac aaaaccaatg gtatcgtgca aagacgttgg acacagattg
    55141 ctgcgccaga gctatcagca gctattgacc gcacgattgg caaaggctgg cgcaaggata
    55201 ttcaccagct tcgacaattg agtcaattta cagaagatcc agctgtgcta aatgattttt
    55261 atcaggtaaa acaagcagct aagcagcgcc tagccaggta tatcctggaa aaaacaggtc
    55321 ttgaggtttc aacagaggct atttttgatg tgcaggtcaa acgcctacat gcctacaagc
    55381 ggcagctcct gaacgtcctg catattatga agctttacct tgatttgaag gctaatccag
    55441 atttagatat ggtgcctaga gtctttattt tcggcgcaaa ggctgcacca ggctatcatt
    55501 ttgccaagtc ggtgatcaaa atcatcaatg agctggctaa tctcattaac catgatacca
    55561 gtctcaaagg aaagctaaag gttgtttttc ttgaaaatta taacgtgagt ctagcagagc
    55621 tcattatccc tgcggcagat atttcagagc agatttcact ggcctccaag gaagcctcag
    55681 gaacatcaaa catgaaattt atgatgactg gtgctatcac cctagcgacc cttgatgggg
    55741 caaacattga aatcaaagac gaggtcggag aggaaaacat tgtgatcttt ggtatggata
    55801 aggatcaggt ctatgaccac tatgccaagc atgattatta ttcaagaggc ctatatgaga
    55861 gcgaccctca gattaaagca gtagtcgacg cttttgtcaa tggcaccatt ccaaatagtc
    55921 aacacgaagg tatggaaatc tatgatgccc taatcacgca taatgatgaa tacttcttgc
    55981 tagaagactt ttcttcctat gtaaaagcac aggctaagat tgatcggctc taccgccaaa
    56041 aggatagatg gtcaaaaatg tcgctcatca acattgccca ttctgacaag tttacatcag
    56101 atgataccat cacccagtat gccaaggaca tttggcagct aaaacgctaa tccatcaagg
    56161 aagaaaaagc attagttacc ttagattgaa gagagtgtct tttgagacca ttttcttcaa
    56221 tcttttttga ttgcaaaaga ccttgggaat cagatcagct gcctgcctaa tactttggcc
    56281 tatcaaggta ttttggaatt tgttaatctt tttgttataa tagtggtgtg aagctatttt
    56341 ttaaatgaaa aagccaacac ttcaagatgg tgttaaagta aggttagtat tagtctaaga
    56401 aagcgtaacc acattaaaga aagctgttga cattctcaat tttaaggaat agaataacaa
    56461 agtaaaaaat ttttaaaagg agtattctat tatgaatcct attttcgcat tggctcttgc
    56521 ctgctttggt gtatcacttg ccgaaggctt tttgatggct aatctcttta aatcagcgtc
    56581 acgccaacca gaaattatcg gtcaattacg ttccttgatg atcctaggtg ttgcctttat
    56641 tgaaggtacc ttcttcgtta cccttgttat ggccttcatt ctaaaataac agcctatttg
    56701 atatagaaaa ggagggtatt aaatggaaga agctaaagta ccgatggtag agcttggtcc
    56761 aataaccttt aatttgaccc tacttgctgt ttgtattgtt actatcctac tgatatttgg
    56821 ctttgttttt tgggcaagtc gtcagatgac attaaaacca aaaggcaagc aaactgcgtt
    56881 agaatattta atcagctttg ttaatggtat tggggaagag catttggata gtcatcttca
    56941 gaagtcttat tcgcttttac tttttaccat ttttcttttt gtggcagttg ccaacaactt
    57001 gggcttattt acaaagctag aaacaaccag tggctacaac ctatggacat cgccaacagc
    57061 taatttggcc tttgacctag ccctatctct gtttgtgacg cttcttgttc atatcgaagg
    57121 cattagacgt cgtggttttg gcgcttattt aaaacgcttt gcgacacctt ggccaatgac
    57181 tccgatgaac ctattagaag aatttaccaa cttcctatca cttgctatca ggctgtttgg
    57241 taatatcttt gcaggagagg ttgtgacagg cttgattgtt cagctggcca attatcgcct
    57301 gtattggtgg ccaattgctt tccttgttaa tatagcatgg acagcctttt ccatatttat
    57361 ttcctgcata caagcctttg tatttacaaa attaacagca acgtatttag gaaaaaaagt
    57421 taatgaatca gaagaataag aagggaggac aaacgaatgt cagttacaat tggtgagctc
    57481 attgggaatt ttattctggt aacaggctct gtcatcgtct tgttgctctt gattaaagcc
    57541 tttgcttggg gtgctatcga agctgtttta caggcacgct cacagcaaat ttcacaggat
    57601 attgaccaag cagagcaggc gcgtctcaac gcccagcagc ttgaaaagga aggtcaagcc
    57661 aatctagaag ccagcagatc agaggctagt cagattgttg aggcagccaa agaaactggt
    57721 aaagcacagg agacacgcat tgtagcagag gctacagaag aggcagatcg cctaaaagca
    57781 gcagcgttga cagatatcga acacagcaag tcagaggcta tttcagccgt taagacagaa
    57841 atgtcagatt tgacagtttt actagcagaa aaaattatgg gagccaatct tgataaggcg
    57901 gctcaaagcc agcttattga tcgctatctt gatgatttag gagaggctta atgaccaaaa
    57961 aagaacaagc tcttatcgag caatatgcaa aaagtcttgt gcaggtctgt caggagcgag
    58021 acactcttga agcactgcag gctgatgtgc ttgccatttt agaggttttt aaagctacta
    58081 atcttgctaa gacattgtca agcttagcgg ttccacgtgc taaaaggctt gagctagtaa
    58141 ggcagcttca aggagataat atcgtttatc tgaataactt gctagaagtt atgctgcaaa
    58201 atgagcgtga agcttattta tatcaagtgc ttctaagggt tttatccgag ctggctagtg
    58261 tctcaaatca atatgacgtg acagttacat cagcagttcc tttaagtgag gagcaaaagc
    58321 agcgtgtgcg tacagtggtt tcaaagagac ttgcagtaaa gacaggtcgc ttaatcgaaa
    58381 aggtagatcc ttctttaatt ggaggattta tgattagcgt caataataag gtaattgata
    58441 caagcattcg tcgtcaatta caagcattta aaatgaattt aaaatagaaa gtggtgtgac
    58501 ttttggcaat taatgcacaa gaaattagcg ctttaattaa aaagcaaatt gagaacttcc
    58561 agccaaattt cgatgtcaca gaaactggag ttgttaccta tattggtgat gggattgcac
    58621 gtgctcgtgg cttagacaat gcgatgagtg gcgagcttct tgaattttca aatggtacct
    58681 tcggtatggc tcaaaaccta gagtcaaacg atgttggtat cattattctt ggtgattttt
    58741 caacgattcg tgagggtgat gaagtcaaac gtaccggtaa aattatggaa gtgccagtcg
    58801 gtgaagctct cattggacgt gtggtcaatc cacttggtca gcctgttgat ggcttaggtg
    58861 acattgagac aactggcttt aggcctgttg aaactccagc tcctggtgtt atgcagcgta
    58921 agtctgtttt tgagtcctta caaaccggtc taaaggctat tgatgctttg gttccgatcg
    58981 gtcgtggcca gcgcgagctg attatcggtg accgtcagac aggtaagacg tctgtagcca
    59041 ttgatgccat cttgaatcaa aaggggcagg acatgatttg tatctatgtc gctattggtc
    59101 aaaaggaatc aacagttcgg acacaggttg aaaccctacg tcgttatggt gctttggatt
    59161 ataccattgt tgtaacggct tctgcttcac agccatcacc cttgctgttt attgcacctt
    59221 atgctggtgt tgcgatggca gaagagttta tgtacaatgg caagcacgtt ttgattgttt
    59281 atgatgacct gtctaagcag gcggtagctt atcgtgaatt gtcgctcttg cttcgtcgcc
    59341 caccaggtcg tgaggcctat ccaggagatg ttttctacct gcatagccgc ttgcttgagc
    59401 gctcagctaa ggtgtctgat gacttaggtg gtggctcaat tacagcctta ccatttattg
    59461 agacgcaggc tggggatatc tctgcctaca ttgcgacaaa cgtgatttcg attacagatg
    59521 gtcagatttt cttgcaagag gatctcttta actcaggaat ccgcccagct attgatgctg
    59581 gctcgtcagt atctcgtgtc ggtggctctg cacagatcaa ggctatgaaa agggttgcag
    59641 ggactttgcg tcttgaccta gcctcttatc gtgagttaga agcctttaca caatttggct
    59701 cagatctaga tgcagcaacg caagcaaaat taaatcgtgg tcgtcgtact gttgaaatcc
    59761 taaagcagcc actgcacaag cccttgcctg ttgaaaagca ggtggtcatt ttgtacgctt
    59821 tgacgcatgg atttttagat gatgttcctg tagatgatat tttagccttt gaagaagcac
    59881 tttatgacta ctttgatgcg cattatgatc acttatttga aacaatccgt acaaccaaag
    59941 accttccgca ggaggctgag ctggacgttg ctattcaggc cttcaaagca cagtcaaact
    60001 ttaaataaaa gaggggggta ctagtatggc aggctctcta agtgaaatta aggctaaaat
    60061 catttcaacc gaaaaaacaa gcaaaatcac tagcgccatg cgtatggttt cttctgcaaa
    60121 gcttgttaaa tctgagcaag cagctcgtga ttttcaaatc tatgcttcaa agattcgtca
    60181 gattacaaca gacttactga aatcagacct gacaacaggc tcagataatc ccatgctggt
    60241 gtctcgtcct gtgaaaaaga caggctatat tgttattacc tctgataaag gactggtcgg
    60301 tggttacaat tcaaaaatct taaagtccat tatggacatg attcaggaat accatgccgc
    60361 tggcgattat gagattatct caattggcag catcggctca gattttttta aggccagagg
    60421 tatgaatgtt gcctttgagc tgcgcggcct agcagatcag ccaagctttg atcaggtcgg
    60481 aaggattatc tctcagtctg taggtatgtt tgtcaatgag atttttgatg agctgtacgt
    60541 ctgctacaat caccatgtca atagcttgac gagccaggtt cgggttcagc gcatgctgcc
    60601 gatttctgat ttggttgccg aggaggccgc agaagaaggt gtcactggat ttgaattaga
    60661 gccaaaccgt catgtgattt tggagcagct gctgccgcaa tttactgaaa gcttaattta
    60721 tggtgcgatt attgatgcaa aaacagcaga gcatgctgct ggcatgactg caatgcagac
    60781 tgccactgac aatgccaagc atgtgatcaa tgatttgacc atccagtaca atcgtgcgcg
    60841 tcaggcggcc attacacaag aaattacaga aattgtagct ggtgctaatg cacttgaata
    60901 agcttattgt atgctgatag cgctctagca gagacctatt agcacttaat gtcatcttca
    60961 aagctagatg acatttggga ttaatgagct aggggccttt tacccttagc tactcgaatt
    61021 tagaaaaatt cagcttaatc ccctactatc gaatataagg agaaaaacat gagctcaggc
    61081 aaaattgctc aggttgttgg tccagttgta gacgttgtgt ttgcgagtgg ggacaaacta
    61141 ccagagatta ataatgcgtt gatagtttat aaagatggcg ataaaaagca aaaaatcgtt
    61201 ctcgaggttg ccctagagct tggagacggt atggtacgta caattgctat ggaatcaacc
    61261 gatgggctta cacgtggatt agaggttctt gatactggtc gtgccattag tgtaccagtt
    61321 ggtaaagaga ctctaggtcg tgttttcaac gttcttggtg aaaccatcga cctagaagca
    61381 ccatttgcag atgatgttaa tcgtgaaccg atccataaaa aagcaccagc ctttgatgaa
    61441 ttgtcaacat catcagaaat tcttgaaaca ggtatcaagg ttattgacct gcttgcccct
    61501 tacttaaagg gtggtaaggt cggtcttttc ggtggtgccg gagttggtaa aaccgttctt
    61561 atccaagaat taatccacaa tatcgctcaa gagcatggtg ggatctcggt atttaccggt
    61621 gttggtgagc gtacgcgtga aggaaatgac ctttactggg aaatgaagga atcaggcgtt
    61681 attgaaaaaa cagccatggt ttttggtcag atgaatgaac caccaggagc ccgtatgcgt
    61741 gttgccttga ccggcttgac aattgctgaa tatttccgcg atgttgaagg ccaagacgtc
    61801 ctgctcttca ttgacaatat tttccgcttt actcaagcag gctcagaggt atcagccctt
    61861 ctaggtcgta tgccttcagc cgttggttac cagccaacac ttgccactga aatgggacaa
    61921 ttgcaagagc gtatcacctc aacgaaaaaa ggctctgtta cctctatcca agccatctac
    61981 gtgccagctg atgactacac tgatccggcg ccggcaacag catttgctca cttggattct
    62041 acaactaacc ttgagcgtaa gctgacgcag atggggattt acccagcggt tgatccactg
    62101 gcttcaagtt cacgcgcgct gtcaccagaa attgttggtg aggagcacta tgcagtagcc
    62161 acagaggttc agcgtgtctt gcagcgctat cgtgaattgc aggatatcat tgctatctta
    62221 ggtatggacg agctgtcaga agaggaaaag acattggtag gacgtgcgcg tcggattcag
    62281 ttcttcttat cgcaaaactt taacgtcgca gaacagttta caggccttcc tggctcttat
    62341 gttccagttg ccgaaaccgt tcgtggcttc aaggaaatcc tagaaggaaa gcatgaccac
    62401 cttccagaag acgcctttcg tgctgttgga ccaattgagg acgtgatcga aaaagctaag
    62461 aaaatgggct tttagtgagg tgatgccatg acacaaatga ctgttcaggt ggttacgcca
    62521 gatgggatca aatatgatca tcatgctaag ttcatctcag taacgacacc agatggtgag
    62581 atggggatct tacctaacca catcaatgtg attgctcctt tacaggtgca tgaaatgaag
    62641 attcgtcgtg tcagtgaaga cgatcgcgtt gattgggttg ctatcaatgg tgggatcatt
    62701 gagatcaaag acaacgtggt taccattgtt gcagattcag ccgaacgtga tcgtgatatt
    62761 gatgttagcc gagcagagcg ggcaaaattg cgagcagagc gtgacattgc agaggctgaa
    62821 accactcatg atattgatga ggtgcggcgt gctaaggttg ctttgcgacg tgccttgaac
    62881 cgcatcaatg ttagtaaaaa atagtaaaat gagtctaacc taccaattta accaagacag
    62941 agcgagtagc gctgcttagg aaagggtgta gatagactct tttatctttt tatagaaaaa
    63001 ataccctctt t
//
LOCUS       DARYUW010000003        56684 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYUW010000003 DARYUW010000000
VERSION     DARYUW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56684
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(140..505)
                     /gene="rplL"
                     /locus_tag="TVW11_000155"
     CDS             complement(140..505)
                     /gene="rplL"
                     /locus_tag="TVW11_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1364303.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(570..1070)
                     /locus_tag="TVW11_000156"
     CDS             complement(570..1070)
                     /locus_tag="TVW11_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1364304.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(1099..1234)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1366..2007)
                     /locus_tag="TVW11_000157"
     CDS             complement(1366..2007)
                     /locus_tag="TVW11_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1364305.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(2004..2771)
                     /locus_tag="TVW11_000158"
     CDS             complement(2004..2771)
                     /locus_tag="TVW11_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1364306.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(2771..3523)
                     /locus_tag="TVW11_000159"
     CDS             complement(2771..3523)
                     /locus_tag="TVW11_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1364307.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(3534..4664)
                     /locus_tag="TVW11_000160"
     CDS             complement(3534..4664)
                     /locus_tag="TVW11_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1364308.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(4731..5417)
                     /locus_tag="TVW11_000161"
     CDS             complement(4731..5417)
                     /locus_tag="TVW11_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364309.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(5451..6803)
                     /locus_tag="TVW11_000162"
     CDS             complement(5451..6803)
                     /locus_tag="TVW11_000162"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1364310.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(6856..7812)
                     /locus_tag="TVW11_000163"
     CDS             complement(6856..7812)
                     /locus_tag="TVW11_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1364311.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(7809..8660)
                     /locus_tag="TVW11_000164"
     CDS             complement(7809..8660)
                     /locus_tag="TVW11_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1364312.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            8762..10105
                     /locus_tag="TVW11_000165"
     CDS             8762..10105
                     /locus_tag="TVW11_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1364313.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            10105..10893
                     /locus_tag="TVW11_000166"
     CDS             10105..10893
                     /locus_tag="TVW11_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1364314.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(11517..12506)
                     /locus_tag="TVW11_000167"
     CDS             complement(11517..12506)
                     /locus_tag="TVW11_000167"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1364315.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TVW11_000168"
     CDS             complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TVW11_000168"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1364316.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(14726..16135)
                     /locus_tag="TVW11_000169"
     CDS             complement(14726..16135)
                     /locus_tag="TVW11_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1364317.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(16259..17257)
                     /locus_tag="TVW11_000170"
     CDS             complement(16259..17257)
                     /locus_tag="TVW11_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1364318.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(17337..18305)
                     /locus_tag="TVW11_000171"
     CDS             complement(17337..18305)
                     /locus_tag="TVW11_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1364319.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(18811..20721)
                     /locus_tag="TVW11_000172"
     CDS             complement(18811..20721)
                     /locus_tag="TVW11_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1364320.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(21131..21916)
                     /locus_tag="TVW11_000173"
     CDS             complement(21131..21916)
                     /locus_tag="TVW11_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1364321.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(22022..23683)
                     /locus_tag="TVW11_000174"
     CDS             complement(22022..23683)
                     /locus_tag="TVW11_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1364322.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(23893..24651)
                     /locus_tag="TVW11_000175"
     CDS             complement(23893..24651)
                     /locus_tag="TVW11_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364323.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(24648..25517)
                     /locus_tag="TVW11_000176"
     CDS             complement(24648..25517)
                     /locus_tag="TVW11_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364324.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(25531..26526)
                     /locus_tag="TVW11_000177"
     CDS             complement(25531..26526)
                     /locus_tag="TVW11_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1364325.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            26878..28548
                     /locus_tag="TVW11_000178"
     CDS             26878..28548
                     /locus_tag="TVW11_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1364326.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(28637..29875)
                     /locus_tag="TVW11_000179"
     CDS             complement(28637..29875)
                     /locus_tag="TVW11_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1364327.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(29865..31046)
                     /locus_tag="TVW11_000180"
     CDS             complement(29865..31046)
                     /locus_tag="TVW11_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1364328.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(31109..31585)
                     /locus_tag="TVW11_000181"
     CDS             complement(31109..31585)
                     /locus_tag="TVW11_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1364329.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TVW11_000182"
     CDS             complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TVW11_000182"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1364330.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(33001..33597)
                     /locus_tag="TVW11_000183"
     CDS             complement(33001..33597)
                     /locus_tag="TVW11_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1364331.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TVW11_000184"
     CDS             complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TVW11_000184"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1364332.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(34523..35632)
                     /locus_tag="TVW11_000185"
     CDS             complement(34523..35632)
                     /locus_tag="TVW11_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1364333.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(35687..36475)
                     /locus_tag="TVW11_000186"
     CDS             complement(35687..36475)
                     /locus_tag="TVW11_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1364334.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(36465..37151)
                     /locus_tag="TVW11_000187"
     CDS             complement(36465..37151)
                     /locus_tag="TVW11_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1364335.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TVW11_000188"
     CDS             complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TVW11_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1364336.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(37887..38564)
                     /locus_tag="TVW11_000189"
     CDS             complement(37887..38564)
                     /locus_tag="TVW11_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1364337.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(38631..39149)
                     /locus_tag="TVW11_000190"
     CDS             complement(38631..39149)
                     /locus_tag="TVW11_000190"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1364338.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(39229..39597)
                     /locus_tag="TVW11_000191"
     CDS             complement(39229..39597)
                     /locus_tag="TVW11_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364339.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TVW11_000192"
     CDS             complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TVW11_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1364340.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(41813..42577)
                     /locus_tag="TVW11_000193"
     CDS             complement(41813..42577)
                     /locus_tag="TVW11_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1364341.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(42577..43506)
                     /locus_tag="TVW11_000194"
     CDS             complement(42577..43506)
                     /locus_tag="TVW11_000194"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1364342.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(43521..44159)
                     /locus_tag="TVW11_000195"
     CDS             complement(43521..44159)
                     /locus_tag="TVW11_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1364343.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TVW11_000196"
     CDS             complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TVW11_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1364344.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TVW11_000197"
     CDS             complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TVW11_000197"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1364345.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            46498..46674
                     /locus_tag="TVW11_000198"
     CDS             46498..46674
                     /locus_tag="TVW11_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1364346.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(46830..47467)
                     /locus_tag="TVW11_000199"
                     /pseudo
     CDS             complement(46830..47467)
                     /locus_tag="TVW11_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TVW11_000200"
     CDS             complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TVW11_000200"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1364347.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMDGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TVW11_000201"
     CDS             complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TVW11_000201"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1364348.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(51624..52646)
                     /locus_tag="TVW11_000202"
     CDS             complement(51624..52646)
                     /locus_tag="TVW11_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1364349.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            52893..54146
                     /locus_tag="TVW11_000203"
     CDS             52893..54146
                     /locus_tag="TVW11_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1364350.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            54446..55807
                     /locus_tag="TVW11_000204"
     CDS             54446..55807
                     /locus_tag="TVW11_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1364351.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            55807..56643
                     /locus_tag="TVW11_000205"
     CDS             55807..56643
                     /locus_tag="TVW11_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1364352.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        16458 a        13418 c        10673 g        16135 t
ORIGIN      
        1 aaaataaaaa ccctgccaaa aaatctttgg tagggttttt agcaggaaac caaatcaatt
       61 tatcagtttc tctaaatcgc tctaagcaat cattaaacct tgatttacta ggcttccgca
      121 atcaaattgc gatactctat tatttaagag tgatagttgc tccagcttct tcaagcttag
      181 ctttgatttc ttctgcttct gctgctgcaa caccttcttt gatgttagca ggtgcgccgt
      241 caacaagacc tttagcttct ttaagtccaa gacctgtgat ttcacgaact gccttgataa
      301 caccaacttt tttgtcacca gcagatgtca actcaacgtc aaatgaatcc ttagtagctt
      361 cttcagcacc accagcagca gctacagcta caggagcagc tgcagtcaca ccgaattctt
      421 cttcgatagc ttttacaaga tcgttaagct caaggattga agcttcttta atttcagcaa
      481 taatgttttc aatgtttaat gccattgtca tttcctccaa atagttatat taaataatga
      541 tttgtagctc taggctacct ctaaaggcct tacgcagcgc cttctttgct ttctgcaaca
      601 gccttgacag cgtatgcaac gttgcggact ggagcttgaa gtacagaaag aagcatagaa
      661 agcattcctt cgcggtttgg caatgctgca agtgcttgaa tttcctcttt tgaagaaaca
      721 acaccttcga tagcaccacc tttaatctca agtgcttcag cagttttagc aaagtcgttg
      781 atgactttag ctggtgcgat aacatcttca tttgaaaatg ctactgcaga tggtcctacg
      841 aatatatctt ttagctcgtc aagacctgct ttttcagctg cacgagtcaa gattgagttt
      901 ttgataacct tgaactcaac gccactttca cgaagtgaac gacgaagaac agtatcttga
      961 tcaactgtaa gaccacgtga atctacaaca acgatactta cagctgcttt cattttctca
     1021 gcgataagct caacttgttc agctttttta gcgataattg cttcactcat tagttttacc
     1081 tccgttttta tttttgggct aggcacaaaa aaatcgcacc taaacctaga cacgaaagta
     1141 caaatacgtt atcttcaata atgacgtttt gtgcctcggc aggaatatta tgagcacgct
     1201 cccctgctgt cttaggtcag ttttattcaa aaccatagtt agtatagcct ttttaaatga
     1261 ctttgtcaac ctatttttta gaaaatctta aataaaaaag gaaagctctt ggctttccgc
     1321 taaatagatc tgattagtgg ctcaaaagcg cctcctaact taagcctaat gataagcaac
     1381 ttgtgacgat tgattgctat aacttagccc gatcaagctc cacagtatca tctcataaat
     1441 aaagaagaac aaggcaaagc aatgcccaaa aaaggcctct ggcaaaatcc aaatgacagg
     1501 atctgtcagc ggatcaaaca accagcttga atctcctaca aagagaattt gatgaaaaag
     1561 ggtaaagaac tgatcaaagc caatcattaa agcaaagcaa gcaatcacaa ttggcaataa
     1621 ggctgctgct attagccctc ttcgaagcag cataaccctt ccttttttga tgctctgata
     1681 aaaatagata atggttggca acataagcag gctaaagatc agctgtgtta tatgaaacag
     1741 cattttcaca tctgtaaaat gctttagacc agctcttgat gctgaaaagc tggctagctt
     1801 tagctcacga acaaaaggat tggttaagta agtcagcaat atattatagt tgtggagaat
     1861 agactttttg cacatcaaaa ctgcctgctc tagttgcaaa taatcaacct caatcggata
     1921 aagcagccaa gataaataga tagttatcaa aactgccagt gctagtagcc aaagccaact
     1981 ggcaatgaac ttgccttttt caatcataat agctcccact catctaagct agccaagaca
     2041 tgatcaggct taattggaag gcttggaacc tcttttgcct ttgtaaagcc ggttgttact
     2101 agaatagttg ccatatcatt ttgaattcct gccatgatat ctgtcaggta attgtctcca
     2161 accatagcca cctcagaacg tggtaccttt aagatctcta gggctttatt catgataatc
     2221 gcatttggct ttcctataaa tactggcttc actctagttg ctgcctcaag gagcgcattt
     2281 aaagcgccag cacctggcat tagcccacgc tctgttggaa tatttaagtc aggattggtc
     2341 ccaataaaca aggctccttt ttgaatggca agtgttgcaa ttgataacat ttcataggta
     2401 acctcagtat ctaagccaac aacaacatag gctggatttt ctgtatcctc ggtatagcct
     2461 gcctctgcaa tggcagactt taagccagtc tcgccaatca cataggctgt tttgcctcga
     2521 ttcatatcat tcatgtaatc aacggttgcc attgtagcgg tgtaaatggt ttcaagacct
     2581 gtatgaacgt taaattgatt ggctagcatt tcctgaacca tttcaggtgt tcttgtggtg
     2641 ttgttggtaa ctaagagata agggatacct ttttcctgta aacgcttgat aaagcgctca
     2701 ccagccggga tacgattttt cccttgatag atggttccat ctaaatcaat taaataagct
     2761 ttatagggca ctaatttgtc tcactttctt tagtcgttat aggctgccat ttgataatgg
     2821 cctgcgcatt aagctggcct gatgacctga tctcatggta ggaggtcaaa tgctctagat
     2881 gatagcctga ggttatttga gtgctgggcc tcacctcttt gatataggtc aaggtaaggt
     2941 ggcaaggtct gtggtgtaat aaaaattcat atcccaaaac gtcatacatc caatccaaat
     3001 acttactatt attggcatga ccattcatat caatgtcaaa ataacgaacc tgataagctt
     3061 gaaccatagg atcctgaagc tcatctattt tgataggacg cttgattttc ttaacaaagt
     3121 cagcctgata aggcaccacc aaatcatctg gtatcgcagc tgccttacgt gtttgaggat
     3181 ttagcagggc aaaatgagat aaaatggtca tgatggcatg acctgcctga tcataaatgt
     3241 gaaattgccg gtaacaaaat aatttattgt aagaaatagc ttgcgtttca atggttactg
     3301 tttccccaaa ccttggcata cgatcaatcg ttacatcata atccgtaaca acccaaatca
     3361 agccatattg ctgaagtaac acctcattgc ctcgtccaat ttcagctgat tgtcttgctg
     3421 ataccattaa gcaatgtgct aataaaaggg gcagcttgac atcagcctta acatcacaaa
     3481 aatcaaaaga cagcttaagg ctttcgctat accttaatcc cataacacac ctcctaatct
     3541 aagatgaatt tttcagcgac agaatcacct aaaaagaggc cttttttggt cattctgata
     3601 aagtccttgt cctctaccaa aagcccctga ttctgaagct ctctcacaac aggaccatag
     3661 cgtgactcaa atgataggcc aaatttttct tgaaaccgac tgactgatac tcctgatttt
     3721 tttcgcagac caagaaaaag ctcctcctcc atcatctcct ccttggtgag cacttcctca
     3781 cttaacctag catttccatc tgctactgcc tttaggtaat gctgaatagg aacccggttg
     3841 cggtaacgaa tcccatcaag atagccagaa gcccctgcgc cacagccaaa atactcatca
     3901 ttattccaat acatcagatt gtgcctgctt tcaaagccag gcttagtaaa attagaaatt
     3961 tcgtaatgct caaagccact ggcttccatt tcagaaataa tatactcaaa catctcagct
     4021 tccaaatcct cagtgggcaa atggagcttg ccacgacgca ttttgttcat aaaaacagtg
     4081 tgatgctcta ggataaggct atacaggcta aggtgaggaa tatctaaagc aagtgcctta
     4141 gccacatttt ccttgacctg ctgcatggtc tgtccaggca aagcataaat gagatcgata
     4201 gacatatttt gaaagcctgc ctccttaaga ctagcaatgg tcgtataaat ctgagcctca
     4261 gtatgactgc gtccaatctg ctttaattgc ttgtcattaa aagtttgaac gcctagggaa
     4321 atccgattga cagccgattg ccttaatact gcaatcttat cctcagtcaa atcacctgga
     4381 ttggcctcga tggtaaattc ttcaagctgg tctagctgta ggtgctgctg caaatggctc
     4441 agcaaataat caagctgatt ggctgttatg gctgttggtg ttccaccgcc aatataaagt
     4501 gtcttcaagg agctgatctg ataggattca aattccttaa tcagtgcctc taggtaggca
     4561 tcgacaggct gatttttgat aaatacctta gaaaaatcac aatagtagca aatttgtgtg
     4621 caaaaaggaa tatgcacata ggctgaggtt ggtttttttg acatggtaat attatatcat
     4681 tttagctcag aaattcatgc caagtgatta gctttttgac atgtactaac ctaaggctgc
     4741 ttctttttct ccattctcac aaaggaatga ctactcccat tagcatactg ctcaaagctt
     4801 gaggttggct gatagcccat tttttggtag aggctttgtg cgcctttatt aaagctagcg
     4861 acatttaaaa cataggtttc ttgcggataa gtagtgctag caaaggcttc aatgctgccc
     4921 aaaaaagaaa caccatcttc ctgaccagta gtatcagggg ccataccaag accaatctca
     4981 agctctgatt cctgttcaaa aaagctggca aagccaaaaa gaacaccatt gcgaagcact
     5041 tgaaagtaat gctctccacg cgccttgggt gacaatattg actgatagtc ctcaggatca
     5101 gcagtcatgc tatagcactc ataagctggg ctatagatcc agtcatgcgc aatgatttca
     5161 gcactatgct gtgtcatcgg catcaggtaa aaagaagact cagacaataa gcgatgaaag
     5221 gtcttgttga tatgctttat gcgacgccgc tgcacatcag gctgatctgt ttgataaatg
     5281 taattagcat agccctcctg atattctgga atcattgtca aatacagctt ttgggtcaac
     5341 tcatcaagct gactagcaat cctatccact ctatgcttta tcatattacc tccaattcta
     5401 atgctgcttg atagcataaa aagtgccgaa gcaacgacac tttttctaga ttaatcaagg
     5461 ccaatttccg cacgaacaac cgctgcaatg gtatcaacat aatagtcaac ttcttcattg
     5521 cttggtgcct ctgccatcac acgcaacaat ggctctgtgc cgctaggcct taccaaaatg
     5581 cgaccattac cagccatttc tccttccatc tgagcaataa cctcagcaat agcaggcact
     5641 tccatagcac gctccttcat gctgttgtca acacgaatat taacaagctt ttgtgggtaa
     5701 atagtgacct cactggccaa ttcggagaga gttttacctg tctccttcat gattttggtg
     5761 agctgaacag ctgtcagttg accatcacca gttgtattgt aatccatgat aatgacatgc
     5821 cctgattgct caccaccaag attgtagccg aactgacgca tctcctcaac aacgtaacga
     5881 tcaccaacag ctgttacctt cttatgaatg ccacagctat ctaatgcctt gtgaaaacca
     5941 aggttagaca tcactgttgt cacaatcgta tttttagcta gcaagccctt ctcagaaaga
     6001 tacttgccta tgataaacat gatcttgtcg ccatcaacaa tagcaccatt ttcatcaaca
     6061 gcaattaaac gatcactatc gccatcaaaa gccaatccaa tatcagaggc tgtttctgtc
     6121 accaagtcct gaagcttttc agggtgtgta gagccgatac catcattaat gtttaatcca
     6181 tttggattct caccaataac tgtaatgtct gcatttaaat ctaaaaagac attacgagct
     6241 gaaacagaag ctgcaccgtt agcagtatca agagctatct ttaaaccgtc taaatctgct
     6301 ccagtagtaa ccaagaatct ctcgtacttg cgcaagcctt ctggataatc aaccaaggct
     6361 cctaagccct ccgcacttgg acgtggtagg aggtcctctt tggcatctaa gagcgcttcg
     6421 atttctagct cttgctcatc agccaattta aagccatcac tcccaaaaaa cttaatgcca
     6481 ttgtcaagag caggattgtg actagctgaa atcatgacac cagcactagc cttttctgta
     6541 cggaccaaat aggacacacc aggagttgca agaacaccaa gcttatagac ctctatccca
     6601 acagaaagca agccagcaat cagggctgcc tctagcattt caccagagat acgggtgtca
     6661 cgagcgacaa aaactctagg cctttcagtc tcatgctgac ttagcacata accaccgaac
     6721 cgaccaagct taaaagcaag ctctggggtc aactctacat tagcctcgcc tcgaacacca
     6781 tccgttccaa aatattttcc cataatttat atcagctaaa cgcttcctcc attccatttt
     6841 cctagctatt atgctttatt ttttaattgt tgtcaactga acggttacta ccgaaggctc
     6901 tatagaaacc tgatttgaaa ccaagctgac cgttttgctc gtgtttttgg tgacgtcaga
     6961 aatattgacc tctgccacca cctcatcaat agtttcaagg acctcccgac taccagaaat
     7021 aacagcggtc tgcttggaga gcttatactg gatatctgac agactgtcat ccattagtcc
     7081 aactgcctcg actcgaatag gaactgattt ggtgattttt ttgacagaaa ctgacaaatt
     7141 agccttggct ggatcgatcg cactagctaa aatggtacca tcggcagcta ctgcctgcag
     7201 ggttactcgg ctgctataat tagcatctag cacctgatca tcaggtaatt tagcgacaac
     7261 atgatctatc aaggcaatag tagactcatc acttgtgacc tcaaccttgt caatacctgt
     7321 ttcaattttg ctaatctcat agcccttagc cagctgctta ctatcgacgc tgccacgcac
     7381 cggaaaggtc tttgttttct tatttccaat cgttaccgaa atcttatcag gagaaacagt
     7441 tgctgtcaca ccagtaggta gattgataac ctttagggtc accgttgcag tacctggctt
     7501 actctttgtt agatcagcta cgatcttaaa gcttctagtg tcactgttta cctctgaatc
     7561 cagctttatg cggttggtag aggtcagata aacctctgca ccgtaagaat agccgctgat
     7621 gaagtactga tcactatcat acttgatatc aataggaacg tcctttaagc tatgggtgta
     7681 ggtttcaata gggctataaa tttgagaatt agaatgatta tgactgctag aagcagcggt
     7741 caaaaaaaga ataatcgcaa aaaagattga cactaagccc agcccaagac gactatttaa
     7801 aaacctcttc atttagcttt gcctcctaag atttttttat accaaggtaa tgtcgcaccg
     7861 ggctcattca tcaaatgagt cttgagaacc gcctcaagct cttctgttga aaggtcgtgt
     7921 aaaaattgac ccttacgagc gatagagaca gctcctgtct cctcagaaac aattatcgtt
     7981 acagcatcag aattttctga aagtccaatt gctgctctgt gacgtgttcc aaattctttg
     8041 gaaatcgaca ttgattcaga caaggggaga taagcacagg ctgcagcaat tttattgtta
     8101 gccacaatga ccgcaccatc atgcagcggt gtgtttggga taaagatatt gatcaatagc
     8161 tgactagaaa tatcagcatt taggggaatt cctgttgcga tatattcctg caaggtctgc
     8221 gtttgctcaa tagcaatcag agcaccaatc ttccgcggtc ccatataagc aactgatttt
     8281 aagagcgcat caaccagcat ctcctcatca ctcaagcttt gcttttgcaa aaatacctgt
     8341 gttgatcggc caaatttttc aagccccgct cgaatttccg gagcaaaaat caccacacct
     8401 gcaatcactc cataggtgat gacctgattc atcagatagg ttatagtcgt aaaccctatc
     8461 cactcggcaa tcacacgaat gatgataaag aatataaccc cttgtaccaa ggacatgatc
     8521 ttagttcctg ccaaggattt aataaaacgg taaatcaaat aggctactat taaaatatcc
     8581 agcaaatgaa ccaccaacat caaggggtca tcaatcaggc ttagtaaaaa ttttgtgtca
     8641 atacttgata aattactcat acaattctca tttctatgtc agatagatac ctctaacatt
     8701 atatcacgtt tcaagatgtt ttccctatct aaaatttaag aacttatgtt aaaatattaa
     8761 catgaaacta aagacactac tcgctatagc agccggaagg actgcgcagc tcattttaaa
     8821 taaaatcgga agaggctcaa cctaccccgg acgattggcc ttgatgtggg ataaggatat
     8881 tttagacaca cttgccaagg actatgagat tgttgttgtg acagggacaa atgggaaaac
     8941 cttaaccaca gctctaactg ttggtatcct aaaagaagcc tttggtgagg ttttgactaa
     9001 tccaagtggc gccaacatga tgacagggat tacctctgcc tttttatctg ctaaaagaaa
     9061 aaaaacaggc aagcctattg ccgtcttaga gattgatgag gcaagccttg caagggtaac
     9121 aacatacatt aagccaagtc tttttgttta cactaatatc tttcgagacc agatggatcg
     9181 ctacggtgag atttacacca cctatcagat gattgttgat ggtgctagtc aagcgccgaa
     9241 ggcaaccatt ctagctaacg gtgatagccc tatctttgcc tcaaaggacc tggttaatcc
     9301 tgttaaatat tatggctttg acacacctaa gcatgagcca cgcctagctc actacaacac
     9361 tgaaggcatt ttgtgcccaa aatgtgaaca gattctccgt tatcgtctca acacctatgc
     9421 taatctagga gactatacct gcttaaattg tgatttccaa aggcctaagt tggattacaa
     9481 gctaacgcaa ttaaccagca ttacccatca tagctcagcc tttgtgattg acgatcagac
     9541 ttatcgcata aatgttggag gactctataa catctataat gccctcgcag ctgttgctgt
     9601 tgctgagttt tttggcattt ctgctgatca gattaaggct ggcttcaata aaagcaaggc
     9661 tgtttttggt cgtcaggaaa ccttctccat caacggtaaa gcctgtacgc tggttctcat
     9721 taaaaaccct gtgggtgcta gtcaggcact agaaatgctg cgcctagccg attatccctt
     9781 tagcctatct gtgcttttaa atgctgatta tgctgacggt attgacacaa gctggatttg
     9841 ggatgctgat tttgaattga ttaatcaaat ggacattact gagatcaacg ccggtggggt
     9901 tcggcattct gaaattgcaa gacgcttacg agtgacaggc tttgatgagg ctaaaatcac
     9961 atcattcgat aagcttgaag gtatcatgca agccattgaa aaccaagagg ctgagcatgc
    10021 ctatatccta gcgacctata ctgctatgct agcatttcgt gagctgcttg ccagccgcca
    10081 cattgtcgaa aaggagatga tctaatgacc tatacctcgc tacaatctcc ggaaaatcgc
    10141 gattatcaat acgaccttca tattgctcac ctttatggta atttgatgaa tacctatggc
    10201 gataacggca atgtcttgat gttgaagtat gtcgctgaaa agctaggcgc taaggttaga
    10261 gttgatattg tatccattgg ggataccttt gaccaagatg attatgacat tgttttcttt
    10321 ggtggtggtc aagattatga gcaagccatt gttgctagag atttgccatc aaaaaaagag
    10381 gccttagcag cctatattca ccaaaataag gtactccttg ccatttgtgg tggctttcag
    10441 ctgctgggac agtactatat tcaagccaat ggccttaaaa tcaatggcat tggggttatg
    10501 ggacattata ccttaaacca agataataac cgctttatcg gaggcattaa aattcacaat
    10561 gatgactttg acgaaaccta ctatggcttt gaaaatcatc aaggacggac ctttttatct
    10621 gacgatgaaa agcctcttgg acgtgtcatt tatggaaatg gtaataataa agaggaccaa
    10681 actgagggcg tccactataa aaacgtttac ggcagctact ttcatggacc aatcctttcg
    10741 cgtaatgtca gcctggccta tcgcctagtc acaactgctc tcaaagaaaa atatggctcg
    10801 actgtttcct tagcggccta tgataagatc ttacagcatg agacctcaga ggaatacgct
    10861 gatgttaaaa gcaaggctag ctttgacagt taagtccttc tcatagcctg attaaaccac
    10921 aacagacatg caaaacagtt attcccgaat gaaaatatag atttaaatag acaccctcaa
    10981 tgtttttcct atcataaaat ccataaaaga taagacatat tcttgcaata actgaacatt
    11041 gaaagacaga aagctttctg tccttactaa acatctttca tgcgtctgtc gtgctgatca
    11101 agcgagataa ccccaaaaaa gtgctagcac agtaacaaaa tggctatgac catatgtctg
    11161 tgcagctcta ctgtcactgc atagacaggc tagaggggac gccctacttg gttcagcgat
    11221 ctaggggtag gtctagcttg tttgtgctga gtctgtttcg gtagcaaaga ttgaatcctg
    11281 ctataagata ctctcaaaaa gattaaccca aaagccttgc aacacattta acgtttttag
    11341 ggataagtac cgatatgcag acacatagca ggagatctat gtgtctggta ccaaaggaca
    11401 caaaaaacta aagtaacaca ctaaaagcca catgataccc atttgatagg gggcgtcatg
    11461 tggctttttt ctatctcact gttcattaca aaaagccaaa ccagcttctt tttgcattag
    11521 gcaacaatgg cctttgccac ctcttctact gtcatacgtg agaaatattg tgttgtatca
    11581 atggtttgaa gacgctcaag cacatcagca tactcgtatt tgcaaccaat gagtaggctt
    11641 tcaatatcct gcacgtcctt aataccaaag aaatcaccgt agatcttaag attcttaata
    11701 acagaatttt caacattagc aaaggttgag attttaccgg cagggtagcg aacattacgt
    11761 tcaatcgtgt attcaggtgc ctttccatag gtccaatccc agctcccaaa ttgctcctca
    11821 gccgattgtt gaatcttagc cagctcgtcc tctgacaaga cgtattctgt catgtctgga
    11881 taggtctcct tcattttaac caaaatcttg tctgaaaatg cttctacgct gattttttct
    11941 ggcagctcat ttaaaatatt ggtcacgcgg gctcgtacag atttgactcc tttggactca
    12001 atcttatcct tactgacctt gagcgcatca ccaagaacag tcatatccac atcaaacaag
    12061 agacagccat gatgcatcat acgtccctta taataggctt gagcattgcc acagattttc
    12121 ttgccatcaa tttcaatgtc attgcgacct gtaaaattag ccttaactcc taaatcagcc
    12181 aaggtctcaa taactggctg tgagaaggtt ttaaaatcaa aggctccttc tgttgtttta
    12241 ttggaaataa tcgtgtagtt aaggttattg agatcatggt aaactgcacc accgccagac
    12301 aagcgacgaa ccacatgaat accatgctgt tcgatgtact ccttgttgat ttcctgaatg
    12361 gtattttgat gcttaccaat aataatagcc ggctcattga tccagaggat aaacaattca
    12421 tcctcatcaa ccaattctct aaaggcataa gcctctagag caatgttaaa ggcagggttg
    12481 tggctcttat taacaatgta tttcatttct atctcctata gcgataatcg ttatcatatt
    12541 ctattcttta ttctaatgga aactcttaca aaagacaagc taaaagaggc tagcaaaagc
    12601 aagggaacta gtaaatgctt cctcaatcaa gaaccatctg caagctagca gtaaagcttg
    12661 atctaactta aagagccttc cttgtatcaa cgaaagagct gagaaatctt tttcccagcc
    12721 cttttttatc gcagctatat agctagctta ttttttacgt tttggtgggt tatgaatggc
    12781 ttcgccaagc acatctgcaa aggcttcgta catcacctct gagaaggttg ggtgtccatg
    12841 aattgacaat agcaattcat caactgttag ctcagcctcc atgattgtgg ctgcttcatt
    12901 gatcatttca gcggctgctg gaccaatgat gtgaacacca agtatttcat ggtatttagc
    12961 atctgcaata acctttacaa agccatgagc ctcgtttgac gcaatagcac gaccatttcc
    13021 tgtaaagcta tttttaccaa taagaacatc gccatattgc tcacgagcct gctcttcagt
    13081 taaaccaacc atagcgacct cagggtgagt atagaccgcc gctggagtgt attttaggtt
    13141 agccttacgt gttgtgctgc catgcatggc attctcagca gccacctcac ccatacggta
    13201 agcagcgtgg gcaagcattt tagtgccgtt aacatcaccc ggtgcataaa tgcctgggat
    13261 tgacgtttct tggtagtcat taaccttaat gcggttacgg tccatttcaa ggttgaggtt
    13321 ttcaagacca ttcatctgtg gcacacgtcc aatagatagc aaggcctttt cagcaacaac
    13381 ctcttcgcca ttattaagct tcaaggtcaa ctggttgttg gcttcaacaa tctcagagac
    13441 accaactgag gtctttattg tcatgccttt cttagaaagg attttttgaa gctccagtga
    13501 aacctccttg tccatggcag gaataatgcg gtcagccatt tcaataactg taacctctac
    13561 accgtaagag gcccaaacaa gaccaagctc aataccaaca acaccaccgc ccataacagc
    13621 aagtgatttc ggcatttcac gcaaatcaag aatatcatca gatgtcaaga caagcttaga
    13681 atcaatccct ggaatattga tgcgtgagac cttagagcct gtcgcaagaa taatattgcg
    13741 ccctttaatg gtttgcacac caatggtaac cgttttatca ggatttacct gaccaaggcc
    13801 attaaagatg gttaccttgt tggctttaag aagcccttga accccacctg ttagcgtctt
    13861 aacaaccgta tttttaaagt caactgtctt atccatgtca atagtatagt tggttgaagc
    13921 aaggttaatc ccgcgtcctg ctgcaatctt gatgccatca aggatttcag catttttgag
    13981 gtaggttttt gttgggatac agccaacgtt taagcaggta ccgccaaatt cagatttttc
    14041 aacgatagca atcttgccgc ccagctgagc accacgaata gcagcgtagt aacccgcagg
    14101 accgccaccg acaacaatga tgtcatattc atcagcagca agctctgcct ttggtgctga
    14161 tggcgctgat ccttgatccg gtgcctttgg cacctcaaga ccagccgcct gtaaatcctc
    14221 ggttgtacgc gcaacattga catcagccgc tgctgggctt gatacatcga tagcttcacc
    14281 cgcagctcca atgtagccga taacttcggt tacagggact gtctcacctg cctggcgaat
    14341 gatttttaaa agcacacctg agtcttctgc ttctaattcc atattggtct tgtctgacat
    14401 gatttccaga agaatgtcac cctcgctgac agtgtcaccc tcctgctttt tccactcgat
    14461 gatctcgcct tcttgcatgt caacaccgag ctttggcata ataatttcaa cagccataat
    14521 gatattgtaa ggaacgttca aatgcaatca gatgccttaa caatcagcac tggctaacat
    14581 aagcctgcta aaagccctgc atttagctca tagctagtga ctacgagctc gttccagatc
    14641 ctttctatag ttttaaagaa ttatcttttc gttactttgt ttctgaaata tgctctcttt
    14701 gcatcgcagg ccataaggcc tgtcatcaga ttagcagttc aaatggattt tccatcaatt
    14761 ttttgagatc aaccatgaat ttagcaccat tcatgccgtc caccagacgg tggtcaattg
    14821 tcagacacat tgccatgatt ggacgtgcaa caatctcacc atcgaccact gttggggttg
    14881 gaatggttgc cccaatacct agaatagctg aattaggctg attgataatt ggattgaagg
    14941 ttttggtgcc aaacataccc agatttgtga tggagaaggt tgagcctgac atttcggtag
    15001 cctttagctt gcctccttga gcctttttga taacgtcctt agaagcaagg acaaactctg
    15061 agagactcat cttatctgca ccatgaacaa ctggcacaac tagcccatca tcaagtccta
    15121 cagcaatacc aaggttgaca aagcgatgaa gctcaatatc attagcatca ttaatcaatg
    15181 acgcattcat gtattcgtgc tctggcttca tcaaggtctt aacaacggct aaaccaatca
    15241 agtcagtaaa gctaaccttt agccctgttt tagccatgat tgggtcaatc agcttcttgc
    15301 gcaaggcaat catttcggtc atgtcaatgt cataattaag cgtaaaggtt ggtgctgtaa
    15361 ggtaggaatg tgtcataccc tttgaaatag ccttacgcat agcagacatc ttcttaattt
    15421 caacaccctc tggaagctcc ttagcaggct tttcttcagc aatagatgct ttttccacag
    15481 caggtgctgc tgcgccaagc acagccaaaa tgtcctcctt ggtaatcttg ccaccaatac
    15541 ctgttccgac caccgctgca aggtcaactc ccttgtcggc agctatctta cgagcaagtg
    15601 gcgttgcctt aggctgagct cctttgaagc cttcaacgtc ttctttgtgg atacggccct
    15661 ttggtcctgt tcctggcact tggttaagct caattcccat ttctgaagct gctttacgag
    15721 ctgctggcgt tgcgcgtacc ttttctccga aggctggagc attggcaact gatgctacct
    15781 gaggcgctgt tgaggctgct tctttcggta cagttgttgt attagcttct gctgatgttg
    15841 gtactggaat ttcagttgtt ttctcacttg aagcagtact attatcaaca gattcacctg
    15901 cagcaccaat atagccgata acctcagtga cagggactgt ttcacctgcc tggcgagtga
    15961 tttttagaag cacacctgaa tcctctgctt caagctccat atttgtcttg tctgacatga
    16021 tttcaagaag aatgtcaccc tcgctaacag tgtcaccctc ctgctttttc cactcgatga
    16081 tctcgccttc ttgcatgtca acaccgagct ttggcataat aatttcgaca gccatatatt
    16141 tcctttcatt taatcccgca gcccatgatc ttaagaccag atacagctgc tgaaaaaagg
    16201 gatactgttt tatcagcctg atgaagaaag cctctaagct aagacttcct ttgccatgct
    16261 aatttccctt gttgaccatt tttacaatag cagccttgat tttagcaaca tctggtaaga
    16321 tagcttgctc aagaacacgt gcataaggta ctggtacgtc ctcactagca agacgcacaa
    16381 ttgggtgatc aaggtaatca aaggcttcac tttcagtgac cattgctgca atctcaccga
    16441 taaagccacc agtcttatag gcatcattaa caagcataag cttccctgtc ttcttaacag
    16501 aattaataat taattcctta tctagtggga taagggtacg tggatcaaca acctccacat
    16561 taataccatc agctgcaagc tcttcggctg cctgaaggac acgctctagc atacgcccat
    16621 aggaaacaat ggttacatca gtcccttcac gcttgatatc ccccttgcca agtgggatat
    16681 aaaaatctgg atcctgattg acctcttctt ttttaccgta caaggcctta ggctccatga
    16741 aaataacaat attgttatca cgaatagctg actttaaaag tccctttgct tcgttagcag
    16801 ttccaggtgc aaccaccttg atcccaggaa tatgcgtcaa ccaagcctca agagattgcg
    16861 aatgctgagc tgcagatcca attcctgagc cagaagcaac acgaaaagtt gctggcgtga
    16921 tcaagccacc accaaacatg tagttgtttt ttgccccatt attaacaatt gcatcaagtg
    16981 caatggtaat aaagtccata aaagtaaggt caacaatcgg acgaagccct gtaattgctg
    17041 aaccaatcgc tgcacctgca atagcagcct ctgaaatcgg cgtatccttg acacgtttgg
    17101 caccaaattc ctcaatcatg ccaacagaag taccaaagtc tcctccgtaa acacctacgt
    17161 cctcacccat aaggtaaatc gtgtcatctt tgcgcatctc ctctgtcatg gcaagattga
    17221 tagcctcacg caaagccatt aattttgttt ctgtcattat tatctcctaa tgtttacaaa
    17281 atagaattgt caatgttact gtgaatagat ttttgctcga tgtgctagca gatcagctag
    17341 tctacccaaa cgtcctcaaa ggctacagaa atgtctggat ctggactatt ttgtgcaaac
    17401 tcataagcgt catcaatttc ttgcttgacc tgtgcttgaa gcgcatctaa ttcttcatct
    17461 gtagcaatgc cttcacctgt taggtaagcg cgatacttaa gcattgggtc cttttccttc
    17521 cactcatcaa cctcttcttt ggtgcggtat ttgccggcat cagcagttga atgaccaaac
    17581 caacggtaag actcaacctc aacaacagca ggaccattgc caccgcgaac atgctcaaca
    17641 gccttactca tggtttcata aactgccatc acatcgttgc cgtcctcaca ataaaagcct
    17701 ggaataccat aagcctcagc acgcgtgtag aggtgaggtg tatttgtggc attgttaatg
    17761 ctcatggaaa tcccatagcg gttgttaatg ataaagaaaa tcacaggaag cttccaagtt
    17821 gctgccatat tgacagactc atggaaggag ccctcatttg ttgcgccatc tccagaaaag
    17881 gccacaacga tattgttggt ccccttgtat tgctgtgtca aggcagcacc taccgcaagg
    17941 gcatagccac ctccaacgat accatttgtt ccatagtttc ctttttcaaa atcagccaag
    18001 tgcattgagc cgccgcgtcc ctttgacaca cctgttacct taccggctag ctcagccatc
    18061 attttattga ggtccatatc tttagcaata gattgcccat gcccgcggtg gtttgaaaaa
    18121 ataatatcat cataggtcaa atgtgccaca gcgccaacgt ttgctgcctc ctcaccaact
    18181 gagaagtgtg tcatgccctg cacaaatcca cgacggacaa gcttattaat acgtgaatca
    18241 aattcacgaa tacgctccat tttaaggaac atatctaaat gttgttcttt agaaactgtt
    18301 accatttcgg cctccatatt atcatattac ttcctaatca taaaactttt cttcacaatt
    18361 tgcaaggatt ttaatcgctt tctttgtgac tataaaagct tttttaagac gttttagttt
    18421 gtggtttcac aagctagatt gttatagcat ctgttacatt tatatataac agattgaaaa
    18481 atgagtcagt gtttattcag ggaggtcaag cacctattga ctttgatagt cagaaatatc
    18541 atcactcttt aagaggaaaa taggctctaa atgacctgtt tcttctagca caatcatgat
    18601 cacctaccaa acgaacgctt tgcttgcctc gctccgatag aggcgaaatg aactaaaaat
    18661 cgcataacta aaaatgcctg attttacctg aaaatcagac atttaaaagc tttaagacat
    18721 tagactcagg ctctaattat aatcctctaa gaaaagcctg ctaccttgca ctacccaaga
    18781 atagcaaggc aatttcatta tctcaccagg ctactccagc tgtcctgcaa tgtcctccca
    18841 ctccagcagc aaggtctcct gtttctgatt aagctgatcc aactcttttt gccagtctat
    18901 cagttgagtc gtatcatttg atactagcat ttgagcttct atagccttag cctgtgcttc
    18961 tagcccttct aaggtctgct caatctcctc aaagcgcctt gttaagcgac ggtattcctt
    19021 ttggctggcc ttttgaagct gataatcagt tacagcagct tctgctacat cagtctctac
    19081 tacgtgatct gcagcagcta gacgggctaa ttcctcccgc tctgcctttt tttctacata
    19141 atagtcgtag tcccccagat agagtgttga gcctgcttca gttatttcta aaaccttagt
    19201 ggccactcgg ttgataaaat acctgtcatg actaacaaac aacaaggtcc catcaaagtc
    19261 aatcaaggca ttttctagaa cctctttgct atcaatatcc aggtggttgg ttggctcatc
    19321 tagaatcaga aaattgtcct ttttcataga taattttgtt aagagcagcc gagccttttc
    19381 gcccccagat agcatggcca cagacttttt gacgtcctca ccagaaaaga gaaaggcacc
    19441 taagcggctg cggatctcaa gctcagctgt cgttgggaaa tcacgccaaa gctcctccaa
    19501 tacagaatta ctaccagtca gatgagattg cgtttggtca taatagcctg tttcaacatt
    19561 agtcccataa tggcatgtcc ctttaatcaa aggaatctct ccaataatgg atttgagtag
    19621 ggttgacttg ccaataccat ttggcccaac aatagcgatt gcatctaacc tacggacatc
    19681 tagatgaatt ggctcagcta aaatatggtc attgtagcca atagcggcgt ctgtcacctg
    19741 caaaacaaca tttcctgagg gcttatcaat ctgaaaagtc atactagctg atttgcgaga
    19801 gctacttggc ttgtctaagc gttctagctt ttctagctgc ttgcgtcttg cctgagcacg
    19861 cttggtcgtt gacgctcgaa caatgttttt ttggacaaaa tcctctagct tagcaatctc
    19921 tttttgctgc ttgtcataat gcttctcttc tgctgcaagc ttttcagcct ttaaatcaat
    19981 aaagcgtgag taattaccaa catagcggtc taagctattt ttagtcagat caagtgtgat
    20041 ggttgcgacc ttatccaaga aatagcggtc atgactgaca atgatcaagg ctccctgata
    20101 atttaccaga taatgctcca gccaggcaat ggtttcaata tctaaatggt tggtcggctc
    20161 atcaagcacc aatagctctg gcttttctag tagcattttt gccagggcca aacgggtatt
    20221 ttgcccacca gaaagctctg agattttcat ttcccacatg ctttcgtcaa acttaaagcc
    20281 atttaaaata gctcgaatat ctgactcata ggtgaagcca tttcgcaagc gaaagctttc
    20341 tgacagccgg tcatagtctg acatgagctg gtccagagct tgccctgatc gactggccat
    20401 atcagcctcc atttgcctta gtcgctgctc atcaaccctc aattcagcaa atacctttag
    20461 catttcctga taaatggtct tgtcagactc aaatcggcta ttttgtgcca aataagatag
    20521 ggttaagtcc ctttttcgac taacctcacc gctagttggc tcttcttctc caactaaaat
    20581 cttaagaagg gttgatttgc cagcaccatt tggcccaacc aaggcaatgc gatcacgttc
    20641 accaacctgc agcgataggt tttgaaaaag cacctctcct gaaaaagagc gctcaatgtt
    20701 atttccttgt aatataatca tacccttatt gtagcaaaaa aatgcccttt tggggggcac
    20761 ttttagttat ttttacaggt aagataagac tcatcaacaa gctaaagaca taagccttag
    20821 gctaacatcg cttatcaccc ttagtggtat ttatctgatg agacaaactg ctgcttgaaa
    20881 aaccagtggg ttgacctgtt agcgtatcca acaatcgcac cacctgctca gttatgcttg
    20941 aaatgctatt agccagtgag gaatcactat ggttcgaata ataaatcaaa ccaaaaataa
    21001 gcaataccaa tactattagg gtctgcaaac agcctctgac aagctgccag acaagcttca
    21061 gcagaagctt tgggaggcat aagaggatag tcagtagttt tttcatcgta ataagcctaa
    21121 attctttcgt ttaggatagc ctttcttcct tgtggtaagc aatcggcagc caatctaata
    21181 gggcctctag ctgctgattc caataatacc attcgtgcct gccatgatcc ttacgataat
    21241 caatagtcaa gccaagcctt ctcaactcag caactgcctt ttcattggct tcaaacaaaa
    21301 agtcctcata gccacaccaa gcgtatagct gggtttgacc atcactttct gctgctatac
    21361 ttgtcaaata atgctttttg atatcaggag cattcaaatc tccaaaaaca ccctgccaat
    21421 aaggcagctc acctatacct tgctgtaata gcatttccgg cgaaaaatgc aaggccccag
    21481 aaaaggaagc agcataggaa aagcgattgc tttttaaggc ccatttaaag gcaccatagc
    21541 ctcccattga cagcccagca acaaaggttt tttcacgctt agtggtcata ttaggaaaga
    21601 aagaagctaa tagccgagga agttcctctg caatagcttg gtaataattc ataccgtagg
    21661 tggtatcggt ataccagcct aaatcagtcg atggcatcac cacgattaaa ttggtatggc
    21721 gaagcagcct ttcaatatta gtccgctttt gccaggaatt ttcatttcct cccataccat
    21781 gtaacagata aagaactgga atatcttggt agccttgctc ttctgggcta agctcagact
    21841 gatcagggta gatcaccttg acatgtcttt ccatagccaa gatctctgaa tgatactcaa
    21901 tgctaatgct tgccatcagc tcacctcctt tttaatatca ccaaagcata aggaaagccc
    21961 actcttaaga cctaaaagcc agatcctatt tgaccagctt ttaggcaggg ctgtatctgt
    22021 attaacggac ctccataaca accggaagaa tagctggccg acgcttggtc tgctcaaata
    22081 aaaaccttga gagctcctct ctaacagagc ctttcaattc actccaatca aaatgatccc
    22141 cttgcagata attgccaact gttgtgttga ccaattcagc actttctcgt aaaatatctc
    22201 tgctcttttt cacatagaca aatccgcgag tgttgacctt agccttagag ataatacgtt
    22261 tttccttttt agatactgtg atcgcaacaa taaaaatacc gtcctctgat aagaccttac
    22321 ggtctctcaa aacaatattg ccaacatcac caatggcatt tccatcaatc atcacatcac
    22381 tagcaggaac cgcaccctcg tgtaagaagc catcctcatc aagcaccatg atgtcaccac
    22441 gcttcataat atgaatattt tcaggtagta taccagcctc ctcagctaaa tgagcatgag
    22501 cagctagatc gcggtattca ccttgaatcg ggaacaggta ttttggtttg acgagattaa
    22561 tcatcagctg caggtcacgc gcattggcat gtccagaaac acgtaaatgc tgcgtgatga
    22621 gcttaacaga gccacctgct ttatagataa ggttttcaac acgagcaacc attgcttcct
    22681 tggcagcgct tggcgttgtg acaatgtaaa ccagatctcc gtccttgatt tgcacgtggc
    22741 gatgacgccc tattgccatt ttctgtaggc tattaatcgg ctcacccata cgtccagcct
    22801 ccagaacaat caattcgtga tcctcaaact tagacatatc ctttggcttg attaatagct
    22861 tttcatcagc aatcactagc tttttaagac gaagtgctgt tctgacaata ttttcagcgt
    22921 cagtacctgt cagtaccact cgcctgctat aggctgctgc agaatcaaag acctgctgga
    22981 tacgaacaag atttgaagcg acagctgcaa taataatccg cccgtcggca tgagcaatca
    23041 ccttatccat ctcctcgcca acctcagctt cgctggcagt ctgctcattg cttgtggcat
    23101 tggccgagtc agctaatagg gctaacaccc cttcttttcc aatgtctgcc aagcgagcta
    23161 ggtctgtctg atagccctca cgcgaagcct ggtcaaactt gaaatcacct gtatagacaa
    23221 tattcccctt atcggttcca ataaccacgc ctaaactttc aggaatagaa tgtgttgtct
    23281 taaagaagga aaccaagcca tctttaaatt caatttctgt gtcactgtcg accacatgga
    23341 aattcttaaa tctcttggtg ctattattgg ccttgacaaa caattttgct agctcgatgg
    23401 tcaattctga accaaatact ggcactggaa cctccgccaa caggtaaggc aaagctccga
    23461 tagcatcagc atgcccatga cttaaaaaga ctccctgaac cttgtccttg ttttcaatta
    23521 cataatcaag acttggaatt accaaatcta cacctagctg ttctgtttca gggtatttca
    23581 agccagcatc caaaatgaac atggaatcgt taatctctac tagatagaag tttttcccgt
    23641 actcacgtac gcctcctaat gcaataatgt ttatatcagt catgatactc ctttttttat
    23701 attagttatt acaaacggtc cttactgggt aagtcgaatt actgtcttgc agctaagctg
    23761 cactctttta cagtatatca tattttaggg cttattacct caaattgcct tgagactttc
    23821 tcaatctttt caatagatta tcaaaaaagc caagggaagg ctttcattcc aatggctttt
    23881 agagtattta ttttagtcaa aaagctggta ataatcagca atggtcattt gagattttct
    23941 cttctgatca aggtcttgaa tgattttacc atttttcatc acaatcaggc gattaccata
    24001 gttaagagcg tcctccatgt gatgcgttat cattaaggct gtcaagcgat ccttagctac
    24061 aaaatcatca gtcaaggcca ttaaggcttg gctggtctta gggtctagcg ctgcagtatg
    24121 ctcatctaat agtaaaagct ctggtctttt tagggttgcc atgagtaagc taagggcctg
    24181 tctttgaccg cctgataaga gaccagtcgg agtctccaga tgattttcca agccatttcc
    24241 aactcgcttg accaagtcag caaagtctgc catataatgg ctaatcctgc gtgatgacaa
    24301 gcctcgcctt tcccctcttt gccttgcaat caaaaggttt tcagctactg tcattcgagg
    24361 tgctgttccc attttaggat cctgaaaaac acgtgatagg tagctagctc ttttttctgc
    24421 tggcaggtgc gtcacatcat gccctaaaag cttaatttga cccttgctta acaatagcgt
    24481 cccagcaatc acattaaaaa gggttgattt accagcgcca ttcccaccaa gaatcgttaa
    24541 aaaatcatgc tcataaatgg tcaaggaaac atcatctaaa atagccttag tctcatcaaa
    24601 gccattattg acttcgacag tagcgtgaat taattcaata atttttctca tcgtgataag
    24661 ctagcctcct taataattgc tttttttagc acaggcacca tcaggcaaag tgctaatata
    24721 atggcactaa atagcttaag ataatttgta ttaaagccaa gagcaataac tactgagatt
    24781 aaaaattgat acaggataga accaaccaca atggctatca agcgctcaag cagggttagg
    24841 cctgtagaat ataaaacctc accaacaata atactcgcaa ggccaattac aatcacacca
    24901 atcccctttg aaacatcagc atagccatct tgctgactaa ccaaggcacc agataaggct
    24961 atcaaggcat tagagatcgc taagcccata agctccatac gatcagtatg aatcccaaag
    25021 ctcttagcca tatcccgatt atctcctgtg gcaatataag cctgaccaat attggtgtaa
    25081 agaaaataca ttaacaaaaa aatcaccaat gtagctacaa ccaaaccagc taccaacaca
    25141 ttggtgtcag ctgcaaaggg aaggtagtcc tgaatgcgct tgatatcatg caagcccaaa
    25201 ttggccctgc ccataaccat aagcataatg gaatggcagg aggtcatgac tagtatgccg
    25261 gcaagaagtg ttggtatctt tccttttgtg tataacaggc ctgtggcgaa gcctgccaag
    25321 gcacccgcca gcatagcagc cagagtagcc aggataggat ttaaaccgag attgagcaga
    25381 gttactgcta cagcacctcc taaaggaaag gacccttctg ttgtcatatc tgggaaattc
    25441 aatattctaa aggtcaggta aatccccaag ccaagaattc cccataacaa gccttgtgat
    25501 acagatgaaa taatcatatg aactcctttt ctattgctta cctgtaaggt cagaacgctt
    25561 cagcaggtct tttgagatca taagacctaa atcccttgct gcctttagat ttaaaaatgg
    25621 cttaccgtca tcaactacct cgacaggaac ctctgatacc tcttttccag ccataagctg
    25681 cagcacctgc ctagctgtct caacccctaa ttggtattga ctttgtgaaa tagaagcaag
    25741 actcccttgc tcaaccattg tatcaacact tgagtagacc ggaagctgtg ctgcatttga
    25801 ggcaacaatc accgctgaaa aagcactggc aatagtatta tcctgtggga taaaaacagc
    25861 atctaccttc tcagtcatca cagacatggt cgtggtaacc tcatttgttg aggggacagc
    25921 gtaagctaga acctccaagc cttgcttttc tgcaagagct gtaaagtcct tgacctgtga
    25981 tattgaattg tcctcactgc ttgcataaag gacaccgacc cttttgacct gaggggtcat
    26041 ctccttgatc agatcaaccg tctgtcgaac aggaacctta tttgataagc cagtaacatt
    26101 tgcctcaggc ctgtctaagt gcttgactaa tttagcacca actggatcag aaatagctga
    26161 catcacaacc gggatagtct tggttgctgc tgctaatcct tgagctgcag gcgttgcgat
    26221 gccaacaaca atatcgtttg ttttgaccag ctgcttgctc atggtctgaa tcttactttg
    26281 atctccttct gcattcataa gggtaatgct gaccttttgc tctggctgat gatgcttctt
    26341 tagctcgtct ttaatgccct gtgcaatctg gtcaagcgcc tcatgagtaa ccagctgcaa
    26401 tataccaacc ttaaccacac gcttgctggc taactgtggc tgttttttgc cctcttttag
    26461 cactagcgaa gcagcaacca ttaaaaagag tgcaatgact gttacgataa gacctttatg
    26521 tttcatgttc tacctcttaa tttccattct tactccgttg ctaacattta gagtactcac
    26581 aaaaagaaaa aacgcttagt aatcagctac taggcgcttt ttttgaaatc caatgtcagc
    26641 gcatagatac ctttttagaa gtactctaaa agtcgtatct atgctaaccc ataaacacaa
    26701 ctttatctat gccagctttg ccaatttatc atatgctgtg tttgcttcat cttggatttc
    26761 ctttcttgtt tttttacatt ataacctaaa agctcaaaaa tacaagagca tttgaacata
    26821 tttttccatt attttttgtg gtataatgaa agaattagaa ctcaggaggg agaaaccatg
    26881 tcatttgacg gctttttctt acatcattta actcaagagc tcaaccatag tattgttaat
    26941 gggcgcattc aaaaagtcaa tcaacccttt gataatgagt tggttctgac tatccgtaac
    27001 catcgccaaa cttacaagct cttgctctca gctcatccgg tttttggacg cattcaactg
    27061 acccaaacag actttcaaaa tcctcaattt cccaatacct ttaccatgat catgcgcaaa
    27121 taccttcaag gagctatcat tgaaggcttt gagcagattg ataatgaccg catcatcgaa
    27181 atgaccgtct ctaacaaaaa tgagattggc gatgccataa agacgacatt gatcatcgaa
    27241 attatgggca agcacagcaa tattattctg gttgaccgtc atgaaaacaa aattatcgag
    27301 tctatcaagc acgtcggctt ttcccaaaat tcctaccgga ctattttacc aggatcagcc
    27361 tatatcgagc ctccgaaaac aactgctgtc aatcctttta cgatctcaga tatcgcttta
    27421 tttgaagtcc tgcaaacaca ggagttatct gctaaaaatc ttcaaaagca tttccaaggg
    27481 cttggccgag ataccgcaca agagctatcc agtctcctga caactgataa gctaaaacgg
    27541 tttagagact tttttcaaag acctagtcag ccaagtctaa ctcagacctc ctttgctcca
    27601 gttgccttct caaacacact gaagaccttc cagaatctat ctcagctgct agattattat
    27661 tatcatgaca aggctgagag agatcgtatc aaccagcagg ccagtgacct gatccaccgc
    27721 gttcaaaacg aattggaaaa aaatcgcagc aaactgatta agcaagaggc tgagctgcta
    27781 gccactgaaa atgcggagga ctttcgccaa aagggtgagc tcttaacaac ctatctgagc
    27841 ctggtgccaa atgaccagga ttcagttgag cttgataact actataccgg ccaaaaaata
    27901 accattgcac ttgataaggc gttgactccc aatcaaaatg cccaacgcta ttttaaaaaa
    27961 tatcaaaaat taaaagaagc tgtcaagcac ctctcaggtc tcatcgctga cacgcaacaa
    28021 accatcgctt attttgaaag cgttgattac aatctatctc aggcaacgat tgatgaaatt
    28081 gaggacattc gagaagagct tattcaggct ggctttgtga aaagccgtaa gcataacaag
    28141 caccacaaac gtaaaaagcc agagcaatac ctggcttcag atggcaaaac aattattatg
    28201 gtcggacgta acaatctgca aaatgaggaa ttaaccttta aaatggccaa aaaaggcgag
    28261 ctctggtttc atgctaagga tattcccggc agccatgtga tcattaagga caatctaagc
    28321 ccaagcgacg aggtcaaaac tgatgctgct gaattggcgg cctattattc taaagcaaga
    28381 ctttccaatc tcgttcaggt ggacatgatt gaagccaaaa agctgcacaa gccaagtggt
    28441 gcaaagcctg gctttgtcac ctatacagga caaaagacac taagagtgac acctatagaa
    28501 agcaagattc aagccatgaa gtgctcccct tcagcctctt cctcatagga ctacagcaat
    28561 aaagataaaa aaagctacag cctcacactt ggagataggt ccagtcttaa agctgcggct
    28621 tttttatcat tacttgttaa tcatctctca aatcatctaa gaagccttgc atatgaatat
    28681 catctggaac ctgctgcaaa tacctttttg cctgcttaac tgcttgatca gtatagccga
    28741 attcccttaa taaataagca taatcctgta aaaagtcagg attttctttt aggtctcctt
    28801 cgatatcttt atagatagtg agggcttttt cttgctgctc cagagcctga taggccttgg
    28861 caagattcca tttagttagc acatgatcaa tctcctcatg ctcaagagca atgacctcct
    28921 caaaacgctc catatccaag tacaggctag ataagcgcat gatgacctct tcgtcatcaa
    28981 cagctacttc cttggccctg agcaaatacc gctctgagcc agctggatca tgcaattcaa
    29041 aggcaagctg tgaagcaagc aacagcagct gggggtcaaa ggcattttta cgcagaccct
    29101 gctgaactag gcgtaaggcc tcttctgtcc gatgctcctc acgcaagctc atggcatagg
    29161 ggtactcgta gcctaaaaag tctgcattca tcgtttctaa ttgcttgaaa tagagattgg
    29221 ccttttggta agcagcctga tcatataaaa tcgtcgccag ctcaaacact gtctcatcgt
    29281 catactcaat ggcaagagcc ttttcaagaa actctacagc agcttcaaat ttccctaaat
    29341 aagcataggc acgccctatg cgctggtagg ttgagatacc tgtcagctca agaatgtgac
    29401 gattatcaag cctagcatat tgctcaatag cctcgctaaa gtgctccaga gacatctcga
    29461 tttcggctaa gccaaagatc actatcggct cctgactcaa ttcagctgct tgaagtagct
    29521 tctcacgcgc cacatcagtt agcccctcca aatcataaag atcagccatg acgagcagag
    29581 cagacaaata atcagcacta tcctctggaa tcctatcaag gtacataaag gcctcttcaa
    29641 tgacattatc ctcagctgca atctgagcaa gattaatatt gacctccgga taagcctcac
    29701 agacctgcaa ataaatcgtc ttagcatgca gtaaaaaacc aatactctct aggtattctg
    29761 ccaaagccaa caaggtctca gcatcgtcct cctgcaaggc tctttgaaaa tagctttctg
    29821 cctgctctaa atcctgttgc tctagtgagg caatcatttt ttcactattt aacatcttca
    29881 gcgaccctct cagcttctgt aggctcttcc tcatacaggc ctgtaatatc cttgtaccaa
    29941 tcaaatagct ccttcacaac aaccttaaca gaagcataaa ctggaatgac aagaaagaca
    30001 ccccagaccc caaacattga ccctgctgtc aataataaaa acataatggt aatcgggtga
    30061 atgctcagct tatttccaag cactagcggc gcgacaaaac gtccttcaat cgtttgttca
    30121 ataacaaaaa taatcaacac cttgatcagc atcaagggtc cttgcaccat tcccataatc
    30181 actacaggaa tcatggctaa aaagctcccc agataaggaa tcatattaag aaagcctgca
    30241 ataataccaa aggtaataga atagttcaaa ccaacaaggc taaacatcac tgaaaacatg
    30301 agaccaacca caatcgcaac ggtcacctgt ccctgcacat agccagataa ttgcttgttg
    30361 atttctccta agacacgtgc cataggctgg cgcagcttaa tcggaagcac attgaccaaa
    30421 ccatttttca tatggccact gtcacgcaga aaataaaaga gaataaaagg tgacatgatg
    30481 attgcaacag taatacgggc aatagctcca gcaaaatttc ctgcccaatc aatagcattt
    30541 ttagagaagc tttgcgcata atctagagcc ttttggctca tactagtcag catatcctgc
    30601 aggttggacc tgtagctaac cagccattcg ttttcaagta gcttattagc ctctagattg
    30661 accttggcaa catatttggg aaggtcttcg acaaagctcc ttagctggtc ttgaatcata
    30721 gggataaagc cagaaatagc ccagaaaaat aggagaatta ctaagccaaa gacaataaaa
    30781 atagaggctg tgcgatttgg acctagcttc tcaaccatat caactaatgg cttggtcaaa
    30841 taatacagga tagttgagat aaccagcggc agcatgataa tggccaaaaa tgacaagatc
    30901 ggtgtaaaga ggaaggatat ttttgtaaag acaaaaatag tcagaaaaac cagcagcgtg
    30961 attaacaaaa ccatcaccgc ctgattattt aaaaaccatt tgtaaaatag actatcatga
    31021 tgattaggct tagaatgcaa tgacattaat ggtatcgtcc tttcttaatt gtggcatcat
    31081 tctgatgaga gcttttaggt tagttgactt aataaaaggt gactgttttt tccactagct
    31141 tgttgtggtc atcataccta aatttagcag aaaaaaacgg ccggtcttcc agtatccact
    31201 tgaaaatgtc gtaatctccc tcccaggttg gcttttccag cacctgatca tagggaaccc
    31261 attctagggt cccttctctg gactcctcat cagcaattaa gtcaccttca aagtctgtca
    31321 ccttaaacac gtaagtatac caatcatgcc ctggtgtaaa atcaggaaag gtaatcactc
    31381 ccttaaagtc cattgctttt accagcaggt gagtttcctc taaaatttca cgtctggcac
    31441 agtcatcagg agattcgcct ggctctaatt tgccaccaac tgaaatccac ttaccttggt
    31501 gaacatcatt ttccttcttg ttgcgatgca gcagcaataa agcctcaccg ttatcaatat
    31561 aacaaatcgt tgctaactta gtcattcata cccttccttt gtttagttgt tactattata
    31621 ccaatctctg agaaatatgc catcatttta tcatttaagc acatcaaaca agaaaaccac
    31681 aatcactaca actcttagcc ctgtactagc aaaaaagcct tgataaggca acgtctgctg
    31741 actcatcaag acttatcact atttaacgaa tcacttcctg tgtcttagcg taattggctt
    31801 caactgcttc tttttcggaa cgccaccaat cctgatgatc agtataccat tggatcgttt
    31861 gctcaagtcc ttctgaaaaa tcagtaaact gtggctccca gccaagctcc tgacgaagct
    31921 ttgtcgaatc aatagcatag cgtaaatcgt ggcctgcacg atccgttaca tggtcataag
    31981 cgtccttagg ctgccccatt ttatccagga ttaattccag cacttcctta ttattttttt
    32041 cgccgtcagc tccaataagg taggtctcac caatacgtcc cttggtcaaa atggcccaaa
    32101 caccagttga gtggtcattg gtgtgaatcc agtcacgaac attctttcct tcaccataca
    32161 attttggctt gataccagac aagatattag tgatctgacg agggataaat ttctcgatat
    32221 gctggtaggg accataatta tttgaacagt ttgaaatggt tgccttcacg ccaaaggagc
    32281 gaacccaggc cttaacaatc aaatcagagg ctgccttggt tgatgaataa ggtgacgacg
    32341 gattatagtt agtatcagcg gtgaattttt cacctggccc ctcaccatga cctggcaaat
    32401 cctcacgcag tggcagatcc ccataaacct catcagtgga cacatgatgg aagcgaatat
    32461 catatttacg agccgcctct aagagtgtat aagtcccaac gaagttcgtg taaataaatg
    32521 gacttgggtc attgagtgaa ttatcattgt ggctttcagc agcatagtgg acaatagcat
    32581 ctgccttagc ggccagctta tctaccaatt cagcatcagc aatgtcacca acaaccaact
    32641 ccacgcgatc acccaaaatc tcctcaaggt tggcacgatt gccagcgtag gtgagcttat
    32701 ccaaaacagt tacgtgaacc tctgggtgat ggttgtaaac ataatgtacg aagtttgaac
    32761 cgataaagcc agcgccaccg gtaacaataa tgtttttata ttcagacatg ttttttcttt
    32821 tcctttgttt tcagctatca gcactcaaaa tgcagcttaa tccgacaggc aagctcagtt
    32881 accagtgaaa acagcgacta agctgcctca cctcattgct cctaccatcc ataaggtcct
    32941 tcctatcaga aggatacaga gacactccca tcaaaagcca tagcttattt caaatgctaa
    33001 ttatgataaa tcttcttgtc tcaaaggctt aacggcctct aggaagggat ggcttttatc
    33061 tgcttctgaa acctctgctt gttcaagact ttcccacgca atcccaaggc ttgggtcagc
    33121 ataattaaca aaggcatatt tttgcttgag ctcaagcgcc caataatcat tgaccagata
    33181 ggtataagcc accttatcag tcagtacttg aaagccatta gcaacacctc gagggacaaa
    33241 aatccccttt gaagcgtcaa tgactgtttg ataggtatgc ccaaagctat caccctcacg
    33301 aagatcaacc caagctccaa gaaccttacc ctcatcagca acagagatgt acttgtccca
    33361 aggctctgca tgcaggcctc gaagcacatg cttgcgcgaa aatgaaatat tgttttgcag
    33421 cttacctgcg gcaaaaaact gctcaggaaa gcctagagga atcatttttt ccttttgaaa
    33481 attttcctta aaccagccac gattgtcccc tcgaacaggg atatcaaact ccaaaagtcc
    33541 aggaatggct tcaatttccc gacaggctaa ggctttatca aaaaattgtt ctgtcatcaa
    33601 gcttctccaa tcaaccgcag caggtactgc ccgtattcgt ttttcttaag cgactgcgct
    33661 agctggtaga catcttcttt agtgatataa cccatgcgat aggcaatctc ctctaggttg
    33721 gccacctgag cgttttgcaa gcgttgaact gtctcgatgt attgggcagc ctccagcagg
    33781 ctttcatgag tgccagtatc tagccaggca aagccacgtc ccatcaactc aaccgatagg
    33841 tcgccacgct ctaaataggc tttattaaca tcagtaatct caagctctcc tctggcactt
    33901 ggtttaatgc ttttagcaat ctcgactaca tcattgtcgt aaaaataaag gcctgttaca
    33961 gcaaaatgtg acttaggaac tgccggcttt tcttcgatag aaatggcatt catctcatcg
    34021 tcaaactcca caaccccaaa acgctccgga tccttgacct gataaccaaa aacagtggct
    34081 cctttttcct tagctgctgc cttttggagc attttcgtaa ggccgtttcc atgatagatg
    34141 ttgtcaccta aaatcaaggc aactcgatca tcaccaataa actcctcacc aatgataaag
    34201 gcctgtgcta agccgtcagg acttggttgc tccttgtagg acaagcttat cccaaactct
    34261 gagccatcgc ctaatagctc ttcaaatctt ggaagatctt ggggagttga aataatcaaa
    34321 atgtctcgaa tccctgccag catcagtgtt gataagggat aataaatcat tggcttatca
    34381 taaattggca tcaattgctt tgaagctgca cgagtaagag ggtacaagcg tgttcctgat
    34441 cctcctgcca gaataatacc tttcatcgta gctctcctca ttttataata cgtcactatt
    34501 ttatcatttt ttaaaaacag tgtcactttt tatcattaat ccgacgaata taatgatgaa
    34561 tcgggtattg actagtatct aagctagctt tttgccccaa aagcagggca atcagctgct
    34621 gagcaatcaa aggacctagg gtcaagccag atgagcctag accgcttgcg gcgtaaacac
    34681 ctggtagctg aggtacctgc ccaaaaaatg gagaaaaatc tctggtatag gctcgaatgc
    34741 ctacgcggta agaaacatca gaggcagaac tcagcttagg gtaataggtc aaggcctcct
    34801 gctccaaggc ctctaaaaca gctacatcag gctcaaggtc atagccctta tcattttcat
    34861 gactcgctcc tacagacaac ctatcatgct caaagggaat aatatccagc tccccctctg
    34921 gcatgaccac tgcgtagtta tctgtagtca cattcgcaat gtgataatca atgagctgtc
    34981 ctttttgcgg tcgaatatcc acctgatagc caagtggctc aagcaattct ggcagccaag
    35041 caccagcggc tagaatcagc cgatcaaaga ccataccatc aacgagatag ccttgctttt
    35101 ctatgcttat gccaacacgc tttttaacca cctgatagcc actagcttca agcaaacact
    35161 gacataggtc tgccccatca acacgtgcag ccccagaagc ccataccagc tgctcaaaac
    35221 cctgtaaatc aggaaaatca accctaatgt ccgaacgaca ccttatcgcc aaatctccaa
    35281 tcaaaggcga ctcttgcttg cgtctaatgg ccagctggta gagctcctct agcttgtcct
    35341 cattcttttt taataaataa acaccagtct gcttataaaa atgtgtagaa agcccctctt
    35401 tttgcagctc cttgattaag tcctgataac aatctgctcc taaccgagcc agctggtacc
    35461 aagccttatt ccttcttttt gaaaaccaag ggcagataat gccagcggct gccttagttg
    35521 cttgaccatt accatcatca aaaatagtaa cctgctgata cccttgtttt tttaaataat
    35581 aagcggcgct tgaacctaca attccagctc caatgattgc tatcgttgtc attgccgttt
    35641 ccattctatc atactgctta ccaagcatag gccatactca gtcatgctat agatgactaa
    35701 agggatttgt tgacgccttg ctagccataa tggttacttg ccagccttcc tcttttttcc
    35761 aagcctgcat cttggcaagt agtttatcaa taaataagga ctcgatgtga tgccctggat
    35821 caattgccag caggccttct gtcagcattt cctgtgctgt gtgataataa atgtcaccag
    35881 taatataaac ttgagctccc ttagcaagcg ctgcctgata aaatttatca ccactgcccc
    35941 cacaaatagc cactcgcgaa atcaaagggt tttgaccagt atatcgaacc agccgaacca
    36001 catcaagccc aaaggcttct ttaactgtaa gtcctaactc ctccaagctt tgctctgcta
    36061 catttccgac acgtccaata ccatacccat cttgcgtctc aaccaatacc tctgtctgct
    36121 caatgcccaa cagctcacaa aaccaatcgt tgagcccgtc agagacaata tctatattgg
    36181 tatgactgac atagacagaa atatcgtgct tcaccagctc aaggacaata tctcgctgtg
    36241 gcgaggagac caagtccttc aagcccttaa aaataggagc gtgcttggtg ataatcaggt
    36301 ctaccttggc cgcaatagct tcggcaacgg tattttctct cacatcaagg gtgatcatta
    36361 cccttttgac ctccttatcc agagagccaa tttggaggcc acacacatct cctgacatgg
    36421 atagctcaag cggacaatag ctttcatatt tttcgatgat tgttctagct ttcatgactg
    36481 atgacctcct caatcgcttt tattttttga gaaatgctag cgcgttcaac aggcttcgtt
    36541 gctggcacac aagacagggc atagacaagc ttatctcgct ctttttgcca tttagccaca
    36601 aagactgatg acctttcctg agacaagaaa ggaccaaagc gctgctcctg atctgttaga
    36661 ctttgttgac caggctctgc aacaatgatt tcataatatt tgccattttc tgtcatgatg
    36721 gtttcagcac taatacaaaa agcattggca gatagccaag cacgcagctc atcctctcga
    36781 ttattgggct gtaaaatcaa gcgctcaatc ccttgcagct tttccttacc agccgctaaa
    36841 atgtcagcta ttaaacgccc tcccatgcca cagatggtta tgcagtctac agcatctctc
    36901 gcctcaaagg cagctaagcc attagccaga cgcacctcaa tatgctctgt caaaccatat
    36961 tgtgacacat tttttagggc tgatacaaaa ggtcccttga ccacctcacc tgcaatcgcc
    37021 tcttgaatat gctcggtttc aaccaaaaaa ataggaagat aagcatgatc acttcccacg
    37081 tctaaaagct tagcaccatc agggacatag gatgccacat ggcgtaagcg ctttgataaa
    37141 tgactttcca ttttcttaat ccttctaaca actaatcgta tcactattat agcaaaatac
    37201 agaccaatta aaaagaaagc cacatcagac cttcttttta ccataggtag tcttgtaata
    37261 gctgcaatag ctctgtactg ggcaggtatc acacttagga tgcttagcca agcagtgata
    37321 gcgtccaaaa aagatcaaac ggtggtgggt gatgatccaa tccttcttag gaagcttggc
    37381 catcaaatca gcttcaattt cagtaacatc ggcatctggg gcagaaatgt tcaagcgctt
    37441 ggcaatcctt gacacatgcg tgtcaactgc gattgcaggg acaccataaa tctctgccaa
    37501 gaccacatta gcagtcttac ggcctactcc tggtaaggat tcgagctcct tatgggtttt
    37561 tggtacctga ccatcaaact gtgtcagtag ctgctgagct gtcttgatga tattttttgc
    37621 cttattttta tacaagccaa ttgtccttag gtgatcctca acatctgaca catttgcctg
    37681 agccaaatct gaaagctctg ggtagctttg ccacagctta ggggtaacct tgttgactgc
    37741 cttatcagtt gtctgcgctg ataggataac cgtaataaga agctgaaagg gcttttcttg
    37801 gtcccaattc agctcgccct tagcctctgg aaacatctca ccaatgattg atagaacctt
    37861 ttttaatcgt tctcttccta tcctcattag ttactccaaa ggttcatcgc cgcaagaaaa
    37921 tcatctgaaa ccgtcacttc agacgccgtc atatcctctc tggcacgctt tttttcctca
    37981 agctgcctga ggcttgtaat tccctccttg cgccaatttc ttagaatagc ctgaatatat
    38041 ttccaattgg tttttccatt aaagacagcc tctctcagcg cctcacgcac taaatccaga
    38101 tctgtttggt catcatgaat ggttttttcc aaatcctcta gctccatcgg actcaaaaaa
    38161 cgacccagct cacgctcaaa ctcatcaaca agaagtttca attggttggt gttttgctgt
    38221 tcatgctcac ccttttcatc acgcgccaat agctggtcta aagtgactaa tacaggacta
    38281 gcatcaaaaa tgatctcaat ctctccagcc agctctatgg ttttcatatc taataacccc
    38341 tgactggtca aggaagaaat agccttattc acctctgcta cagacttacc caaggcatta
    38401 gcaatctgac taggtgccaa ttcgtcaagc ctagtcgtat tttggagata gaaaaactgc
    38461 caaaccaaaa aatcgtctga gctcttaaaa atatccttgt aatgaaacag taaggcagtt
    38521 ggaaggacca aattgccaga ctgataatgc tctaaaaaac tcataattcc cctgccaaac
    38581 gtaatagccc aacctagctt ttaatcagta ctgccattag caagcactga ttaaccagga
    38641 aaatgcatca ataccttaca atcgtaatca ccaatagcct gacgaccatt caagccgtcc
    38701 agctcaatga gaaaagcgca gccagcaaca atgccgccca gcttttcaac cagatcaata
    38761 gtagccttta ctgtaccacc tgttgctaat aagtcgtcca caataaggac acgttggccc
    38821 ggcttaatag catcagcatg catggtcaag gtgtctagac catactcctt ttcatagcta
    38881 gcagaaatca cctctcttgg caatttaccc ggcttacgaa caggagcaaa gccaattcct
    38941 agctcaactg cgaccggaca gccaataata aagccacgag cctccggtcc aacaatcatg
    39001 tcaatgtcct tatcgcaggc atattgcaca atctcacgaa tagcatagct gtaggccttg
    39061 ccactagcca ttagcggcga aatatcacga aaggtaatcc cctcctttgg gtaattctca
    39121 attgaagcaa tatattgtgt taaatccatc gtaaaatagt ctttctaatg tcttttaaat
    39181 taaaatcttt cctattatag catgaaagtc taaaaaggta aatgattcct aatcatccag
    39241 atcaatccct ttttccttta aattagtcag gcattcctgt aaataggcct cttgatgctc
    39301 aggataaatc ggtgaggtca gtgccacctc ctctaagtcc tcataggcgg caaggctttt
    39361 tcctcggtaa tttttatcct gccagctcac atctggctgg tagccccgcg cctgcatttc
    39421 ctgcataatc aacaggtgat actggtaaag cttataaaga gaatgggcaa acacatagtc
    39481 aaccgtcgca tgtggtctcc cccagcctgc tcctcgcaag gccgcacatt cacgatgctg
    39541 ccccaacaat tgctgccttg gtaggcgtgt gattaaatcc tgatgccaaa gacgcataag
    39601 ctctcctatt tctcttcact agtcattaaa tactgataaa tctcctgcgg actgcccaag
    39661 gccataagct cttgaaactt taccagctct tttagctgtt ggtaaatgac actgtcagcg
    39721 atgctacgtt ttggggcatc agtctttacc ctcatcagcc catcttcgat tactacaaag
    39781 cctaactcct caaaaatttg tatcattttg accaagagga ttttttcaat cttgaggtaa
    39841 tcacttagca aggtcagctt atggcgaaga tcaaattctg ggtattgata gatggtctta
    39901 taaagcttgg caaattgctc tctactgcca tagcctgtta ggtaataagg gcgcttaata
    39961 tgatttttaa agtaaatcgc ttcaaattcc cgatgtctaa aaaggccttt caaggcatca
    40021 atatcgtcag gaacctcatc tatgacaaca accttggcct gctggtcctc aacagctgta
    40081 ggaatatgct caggtgccct agcagtcctt gctcgaatat caaacagctg caccccagtc
    40141 actctagcgt caaccagcat taattgcagg ctagtatgac ctcgccagtg attgatcgca
    40201 agactaaccg ctaattccaa gccctgtgat tgctggtact cctgtatcag atgtccctga
    40261 ccaaaggcca agacatcagc ctcaacggct cctttgctga ccttgaactt caagtgactt
    40321 tgttgctgac caatggtcct tgcctgctta atcgtaaaat cttttaagta aaaaacaggc
    40381 tttttattat ccatgccaaa gggtgctaga agtagcagct tgttcagact atctatactc
    40441 aatgcttcta aatccaattc accattgatc aatagagtgt ttttttcctg accatcgtgt
    40501 cccttggctg ccacgtattg gcaaagtagc tctgatagct cctctaggcg atcagatggc
    40561 agagtcatgc ctgctgcccc ctcatgacca ccaaaggctg taaataagct cctattgcta
    40621 ttaagtgctt caaagatatt aatgctctct aagcttctgg ctgagccctt ggctagcccc
    40681 tcatcaatgg tcaaaacaag aacagtctgc ccaatctcct ccatgatccg accagctaca
    40741 atccctaaga cccctgggtg ccagccagac ttagctaaaa cctgcacagg cttgtctaga
    40801 tcaagcatag ccattgcttg agcaaaaatc tcctgtacca agacctttct ttcctcattt
    40861 ttactactaa tcatcaaggc aagctcatga agctcttcgt catcaaagcc tgtcagtaga
    40921 tcaatagctg gatttggatc gtcaagacgc cctagagcat tgagctgcgg agcaagctta
    40981 aagctaataa catcttcatc aaaatgcgct aagtcaacct ctgaaagctt catcagctcc
    41041 tgcaagccta gtctttctgt ctcttttaga acagccagcc cgtttttgac aaggatacgg
    41101 ttttcacctc gtaggctgac catatcagca attgtcccaa tagcaaccag atctaaaaag
    41161 tctactggaa ttgtctctaa cagagctgaa gccaacttga aggcgacgcc acagccagct
    41221 agtttttgaa agggataagc agcagctggg tgctcagggt gaataatagc aaaggcatca
    41281 ggtagctctg ctggcaggct gtggtggtct gttacaataa catctacccc ctgtgcttgc
    41341 gcaaaggcaa ccgcttcatg gcctgaaaca ccattgtcaa cggtaataat cagcgaaacc
    41401 tgctcttgct cgatgaaata cttgtaaaca ctttgattgg gaccatagcc atctgtaaag
    41461 cgattaggca aataaacaag aggctctgct cccatcattt ccagcgtttc cttgacaata
    41521 gacgccgctg tcatgccatc tgcatcataa tctccgtaga ccaaaatcct ctcaagcccc
    41581 tcaatggcct gacgaatgcg atgaacagct ttttccatat catttagcaa ataagggtca
    41641 tggagctgtg ataggtcagc tgtcaaaaag ctggtaagct cctcttcggt atgaacacct
    41701 cggtcataga tgagctttgc agctgtctga ctaagtccct ttgcctgagc tagcttaaag
    41761 aagccagcat ctggctcctt atcagctatg gtccactgat atttggacgt aatcatttat
    41821 aattaaatac ctttcttgca agataatcag atatagttgg aaacaaggta taacacttat
    41881 gagcaagggc taggctaata ggcagattaa tctctcgttt cttttttcct attgcagcaa
    41941 tgattttttt cgccacagta tccgcctgca gcgtaaagcc tgcaacactg gctaaatact
    42001 gcccgcttgg gtcagcctgc tcaaaaaagg aggttgcaat cgggcctgga ttaacagttg
    42061 tcacataaac ctgcctttct gccagctcca agcgaagggc attagaaaag ccaatgactg
    42121 caaactttgt cgcagaatag atacttgact tggcagaagc tattaagcct gccattgaga
    42181 caatattcat aatatgtcca gagccctgct ctgccatttt gtggccaagc aagcgtgcaa
    42241 aatgaatgct ggctaagcta ttcacacgaa acatggcctc aatctcttct gcagagaaat
    42301 catcaaaggc cttaaaagca ccaaagcctg cattgttaat caaaacatca atcctgccat
    42361 ggcgctggta aagctcatca acaagagcct caatagcagc agggtcttga atagcaatct
    42421 cgtagcattc cttattaccg cgagcctgat atagactgtc taacctgtct ttgctgcgcc
    42481 ctaacaaaat caggtaatct tctcttggaa gctgtctgat gatagcctgt gcgagcccgc
    42541 cagaagcacc tgttatcaga ataattctct gtgccattaa atgatcactt cctctaaatc
    42601 gcgaacaacc ttcacatttt caaaaatagt tgccgcatcc ttttccattt gacgacagtc
    42661 acgtcctaaa aagcgtgctg aaacatgatt cagtaaaaga cgcttagcac ctgcatcacg
    42721 cgcgatttga gcagcctgca tgtttgtcga atgcccatga ttacgggcca ttctttcatc
    42781 acccttcccg taggtggact catgcaccag cacatcagca tcttttgcca atctaacact
    42841 agcagatgtc ttgcgtgtat cgccaataat ggtgatgatc tttccttttc gaggctctga
    42901 aataaagtcc ttggcaaaaa ttttggtgcc atcctctagc tcaatatcct gcccattttt
    42961 aaccttgcca aaaagtggac caaagggcac tcctactgct ctaagagctt ctgcatcaag
    43021 tgttccttct aaatcctttt gaaccacacg ataccccata caaaagatgg tatgtgccaa
    43081 gcgctcagca taaacaataa atttatctgt ttctaaaatc ttgcccatag aggtgtcatc
    43141 aaactcatga taatgaatct gataaggcaa tttagagcct gatatcctga tgctgtttgt
    43201 tacataggat tttatcccaa caggtccata aatctcaagg tccgtctgct cctcactagc
    43261 ttgaaaagcc cgactagata aaaagccagg caagccaaaa atatgatcac catgcagatg
    43321 cgtgataaaa atcttcttga tttttcgtgg cttgattgtt gtttctaaaa tttgccgctg
    43381 ggttccctcg ccacaatcaa acatccacac ctcattgatt tcatctaata gctttagcac
    43441 taagcttgaa acgttgcgat gcttggctgg ctgcccagct ccagtaccta aaaattgtaa
    43501 ttccatacag tctattcttt ctaatgcaca aggtaaatca tgaattctct ttgtgcaaac
    43561 tgataatatt tctttccttt gaatgcttgg ctaagagcca acaattcatc actattaaag
    43621 ccctttagca gggtcatttc gtttgagaaa cgatagatcg tggttaacaa agcatgctca
    43681 ggtgttatgt cctctggctc tccttgctca aattggcagc tcttcatctt gattctacca
    43741 tcttccacat aaaccacgta ttgtggaaaa atctgagcca gctccagcag cagcgattcc
    43801 tcaggctgcc cctgctcttt ttcagcaaaa acaatcgcct cctgtgcttc attttcaaag
    43861 acaaagccat aggattgccc caacaaattt aagcggacaa agggcttcac ctcatcaaat
    43921 gacggctctg aggtaaacag cttcaaggcc cttgatagct caaaataata atctgtcgct
    43981 gcttttggtg attgcttctg atacatttct gcaaaataag cattaatcac acttgggggt
    44041 ggcgtgatgg tagctaattt ttgctggtct gtcaagccct ttaagcaatt ttgcaaataa
    44101 accgtatcta aactcgtaaa gcctccataa gtctttgcca attgaatata atcagtcata
    44161 aaattcttct aatctccatt tatttttggg agcaatgtag ccagaaatct cttcaatctc
    44221 cttatcaaag ctataaggct ccaataacgc caacctgttg aggtcatagc atttgtaggc
    44281 ttgatcctga cagagcttga tcgaaaatgg ctcaaacatg tcccgaatct gatcaataag
    44341 caactgtctt aagaggctac gactgttttt atcacgtgct gacagcctga catttggaaa
    44401 aacagttgca gtcaagctag ctgtcttatc catcttgtta taaatagcca gccttggaat
    44461 atccagcata tctaaatctt tcaagatgtc tagaacaacc ctctcatgct ccaaatgatt
    44521 agggtcactg gcatcaatca catgcaagag caaatcaaca tgccgacttt cctctaatgt
    44581 cgacttaaaa gcagccacga gctccgttgg taaatcttgg ataaagccta cagtatctgt
    44641 cagagttgcc tgaaactgat tttgcagata aatttgcttg gtggtggcat caagtgttgc
    44701 aaataattca tcagcctcat attgcttgtc accagtcaaa atagtcataa tagtagactt
    44761 acctgcattg gtatagccga tcaatccaat attaaagaca tcagaggtca tgcggcgatc
    44821 acgaatcgtt tgacggtttt tttcgacagc agctagctgc cgctcaatat ctgcaatctg
    44881 atgacgaatg gagcgccggt tcagctccag ctggctctca cccggcccac gactcccaat
    44941 gcccccggcc tgacgactaa gcataacacc ctgtccgacc agtcttggca gcatgtattt
    45001 gagctgcgct aaatgcacct gcaattttcc ttcatggctt ctagcccgca tcgcaaaaat
    45061 atcaagaatc agctgcatgc gatcaatgac cttaatacct aaggcgtcct ccaaattggc
    45121 attttgccga gccgttaaac gattgttaac aatcactgta tcaatctcat tggcagcaac
    45181 catttctttg atttcagcca gcttaccaga gccaacaaag gtcttgctat catagcgctc
    45241 cctcttttgc agatagcaat caacgacctc tgcacctgcg gtcttggcta gactagccag
    45301 ctctgtcatt gatagctcag catggtcagc tgcttgtagg accacgctta gtaaaataac
    45361 tctttcctgc cttgcctttg tctctatcat gaacgcgact aatcctccaa attccgtagt
    45421 gtttattata gcatagtttt agctattttc agctagtttg ccatcgatag cttcctaagg
    45481 ctccttcaaa aagcgctcca ccctatcata tattgcctgc ggataggacg actcgctaat
    45541 cgagtcaaag cgcactgcca tacggttacg aaaccaagtc agctgtcgtt tagcaaagcg
    45601 gcgtgtttgc tgctttagtg tggctgttgc ttcttctaaa ctagcctgac cctgaaagta
    45661 agggaagagc tccttataac cgatccctcg actagcctga acagctggat actgctcaaa
    45721 aagccacctt gcctcctcca ataggccaga agccatcatc agatccaccc gcttattaat
    45781 ccgctcataa ataacctctc gctcatcagt caagccaatg atcaaggggt tatagggggc
    45841 ctcttgattt tctaaatccc tagcaaattg atttagctca agtgagcgaa tggcacgcct
    45901 gcggttaacc tgatcaaggt gaatgccctt actagctaat agctgataaa gctctgtatc
    45961 tgtcagtgtc tctagctgct gccgataagc aagtagctcc ttttgatcaa gatctcctcc
    46021 tagatgatag ccctctaaca ggctttgcaa atacaggccg gtaccaccga caataatcgg
    46081 cagtttaccg cggctaacaa tatcttcaat agctcgctta gcgtcctgca caaaatcaaa
    46141 ggctgagtaa gactctgtca cctcacgaat gtcaatcaaa tgatgaaccg caagagcctg
    46201 ctccctggca ctagccttag ctgtcccaat atcaaggtga cgataaacct gctgactatc
    46261 tccagatata atttcaccat taaaggcacc agccaaggca atccctagag ctgtcttgcc
    46321 aacagcagtc gggcctacaa tcacaattat cttttctttt gtcatttatt gtctttctac
    46381 ttaaaaagca gctgaaaaag tcttttactt gaattttcta atctttttcg ctaccatata
    46441 ttataacata agattgagag acagttatgg tcctcttaat agaaatggag aatgattatg
    46501 gctaaaaaac atggattcgc aaagggtctt gctacaggtg ttcttgctac tgctgctacc
    46561 gttgcaggtg cagtatttgc tgttaaaaag actattattg accctgagga agaaaaagca
    46621 gcatttgtag aggaaaatcg taaaaaagca gcacgtcgtc gtgttgctcg ctaatcacta
    46681 atagatgaaa gattcgacag gctttatcaa tagcctgtcg aattttttat gctgtgagac
    46741 caagcttttt gcttagacac ataaaagaaa cagctcgtca gcgccgcata ctgcctactt
    46801 cattgaccaa caaacagggc aaactaaggc taattttcac tgatatgaca tgtttcgact
    46861 ataaagcggt tttgtgattg attgatcaca atatcaaatt gctggtgata agggtgcaga
    46921 taacgagcat attgagcgcg cctattgaca tgatgaactc cggattgcga cctctaatgc
    46981 tagtatctct accaagccgc ctttggagct ctgtgtcacc atctgtataa aagtaaagcg
    47041 ataagtcaaa caactctggc tctaaaaagg ttgtcgacat gccttcagca ataaggatgg
    47101 gcacattccc cttcaccaaa aaagagggag accaaggggt atcaatactc aaaaaatcca
    47161 gtccttgctt aaacatcatg atgtcacgcc tcagactggc caattcgtgc ctagcagggt
    47221 gacaggctgt tatactacca agtacctcct ctccctgatc agggtagcta atcaaaacag
    47281 cctgactaaa atcattagcg atgatatagg catctgtttc taacaattgg ctttgtccat
    47341 caggcaaaag ctgctgtaag cgcttagcaa aggttgattt accagatgca ccatgaccac
    47401 taattctaat aagcattttc tcacgattgg ctgctgcagt tacaatagct tgaagtagct
    47461 tctccattat ctctcctcat caaataacat tctaataata ggacatcatt ctacatcgaa
    47521 aaacaagccg gtctcccgaa acagcctgac tgacagtaaa aaaagattga agggcaatcc
    47581 aataaggaaa gcttctccaa tctgattaat agtctataat ggcttaatat gagtgccaaa
    47641 tgtcttggtt atattgttca atcgtacggt ccgatgaaaa gaagccagcc ttagcaatat
    47701 tatgcacaac ctttgtcagc cataggtcct gattgtcata atcagccagc atttgttctt
    47761 tgactgcaat gtattcctca aggtcaatca aggtcataaa ccagtcctta gagattaact
    47821 ccttatagag acggtcaaga cgttcctcat taccaagctc taataattct ggactgataa
    47881 taaagttaac tgcttccttg atagctgggt gggcatcata atagtcttta gacacataac
    47941 cacctgtggc ataaagatca ataatggtat ctgaatcctt accaaaggtg tagatattat
    48001 ccataccagc aagctcagcg atttccacat tagccccgtc catagtacca agcgtcaagg
    48061 caccattgag catgaatttc atattaccag tacctgaagc ttcctttgaa gctagagaaa
    48121 tttgctctga aatatcagtt gcaggaatca aatgctctgc tactgtcaca ttgtaatttt
    48181 caacaaggtg aacattaagg tatggactta cctccggatc gttattgata agctctgaca
    48241 agcaaagaat caaatgaata atatcctgtg caatgatata agccggtgca gccttaccac
    48301 caaagataac tgttatttta cgcttcggca ggttgccttt tttgatctct aagtatttat
    48361 gaatcacata aagggcattc atctgctggc gcttatattc gtggaagcgt ttaatttggg
    48421 tatcaatgat tgaatgctca tcaagctcaa ttcccttatt atccttgagg tagcgcttta
    48481 aggctacttt attatggtgc ttaatttcag ccaatcttgc atgaacagct tgatcctcag
    48541 caaaggccat taatttttca agccttgtcg catcagtcaa gtaagcatca ccgataagct
    48601 ctttaatata gtccgccaac tcttggttgg cgaattctag ccaacgacgg aaggtaatac
    48661 cattggtttt gttgttgaat ttttctggat acagctcata gaaggccttc aattcgctat
    48721 ttttcaggat ttcagtgtga agggcagcaa cgccgttgac acttgtggca aaatgaatat
    48781 ccatatgtgc catatgcacg cgacctgttt catcaatgat ttggacagct ggatctgata
    48841 cccttgcacg aacaagagca tctaattgct cgataatcgt taccagctgc ggcacaacct
    48901 cattaaggaa gtcaagaggc catttttcca aggcttctgc aaggatcgtg tgattggtgt
    48961 aaccatccat cttttgaacc actgaaacag cctcatcaaa atcaaagcca tgcttttgtg
    49021 tcaatagacg aatcaattct ggaatgacca ttgatggatg ggtatcattg atctgcacgt
    49081 atgcgtaatc agctaagtca tgcaggtttg agccacgctc aagcgcttca tcgatcaaga
    49141 gctgagcggc attagatacc atgaaatatt gctggtaaat gcgaaggagc tcaccatttt
    49201 tatcagaatc atcagggtaa aggaacaggg tcaggttttt ggcaatgtca gtcttatcaa
    49261 atgaaatgcc atctttaatc aagccataat caaccccttc aatatcaaaa aggttaagat
    49321 agttcttggt gtcacgctta tagcccaaaa catcaatacg gtctaagcga gatttcaggg
    49381 taaagttttt aaagggaaca tcatatgaaa tgtcagtcgg tactagccaa gagtcatcct
    49441 ctatccaaaa attaggctct gctgtttgtt cattgtgtct aaagacctgc ttgaacaagc
    49501 cacaatgata attcaagcca accccttcac cattaatgcc aaggcttgag atagaatcaa
    49561 taaagcaaga agccaaacga ccaagaccac cattaccaag cgatggctcc aattcaacgt
    49621 cctctacctc agcaattgat ttgcccgcag cagccagctc ctctttgatg tccttataaa
    49681 tacctagatt aatgagatta ttagaaagca acttaccaat caaaaattct gctgagatgt
    49741 aataaacctt acgtttagct gtgttttttg cttttttgct tgcttcttct ttgagatagg
    49801 aaagcaacga aagatagatt tcctcgttgc ttgcacttgc aagagatttt cctaatgtca
    49861 tttcagtata atctgtaaag cgtttcatga tatcctcttt tcaatatagt attctagtga
    49921 tgattattgg ctcgaccgta tagctcagtc aaatggatta aataggcctt gtgctctgct
    49981 ttaatatcgt cctcaagcat gcgccactgc cagttgccac cgacagtgtt tggcatattc
    50041 atgcggctat cagctgactt atccagcaaa tcctgcatac acaggatagc agtatcacac
    50101 acagtcgcaa agattgttct tagcatggcc ttggtgatgc tttcagcagc tgccttatgg
    50161 atataatgat taacaaactc aacctgctct gcgctcaagt gctcatacca gccattcacc
    50221 acctcattgt catgcgtacc agtgtagaca atgcaattgt gatcatagtt atgcggcaaa
    50281 tcaaagcttt gacttgtcac atcaaacaaa ccaaactcta aaatcttcat gcccggaaag
    50341 ccagtagatg ccagcagctg ctcagccttt tcatcaatgt agccaaggtt ttctgcgata
    50401 attggcagct cacccaaggc ctctcgaaca gctttaaata gagcaatacc aggagctgac
    50461 tcccaatgac catttttagc agtcacatca ccaccaggaa tttcccaaaa atctgagaag
    50521 cccttgaaat ggtcaattct aagcttatcg tacagcttga agctctcttt gatccgatgg
    50581 atccaccaag caaagcctgt ttgctcatgg ctctcccagt tgtaaatagg attgccccaa
    50641 agctgcccgt cctcactaaa gccatcagca ggtacacctg caatgtaaat cggcttttta
    50701 tctgcatcca ccttaaagag ctctggcatc gtccaaacct caacgctatc agcagacacg
    50761 tagattggca tatcaccaat gatagtaatg ccattttgat tagcataggt cttcagcgct
    50821 agccactgct gataaaagaa atattggcag accttatgat aggtgatgcc tttggccaac
    50881 agcttgcggt aatgaagcaa ggcagcctct tcacgcttaa caattgctct atcgtcccat
    50941 tcctggaggg ccttgtgatc aaaatgctct ttaatagcca taaattcagc aaaatcattt
    51001 agccagctcg cagttgcttc aaattcggcg agctgtctta agccttcctc agttgagaca
    51061 aaagcctgaa ctgctttttc taataaaggg cgtctggctt gaaagacttg agcgtaatca
    51121 acagactccg gatttgagcc aaaatcaaca gcagcataat cagcttcctg caaataaccg
    51181 tcctttgcca gcaattcaag gtcaataaaa tgcgtatttc ctgcaatagc tgaaaaagat
    51241 tgataaggag aatctccaaa gctagttgtt gttaagggca aaatctgcca ataggtctgc
    51301 ttggtttcct ttaaaaagtc aacaaattca aaggcctctt taccaaagct cccaataccg
    51361 aagcgtcccg gaagcgagct gatatgcatc agaataccac ttgcacgttt agtcattctt
    51421 tttttctcct tgtaaaatct taatgttgaa attataacgc aaccgtttgc gcaagtcaat
    51481 atcttttcaa aaaaaaaaga gactttttcg gcatgctaga gctgctcaag ccttgataat
    51541 aatgagggaa gcagctagga caaaaacaaa aaaaggattg gagagacagc ctaagcagct
    51601 gctcttccat cctcatctca ctcctatttg gcattaatat ccctgacact ctctcgcttt
    51661 ttgaggctaa agggaaccaa aattttctga ctcagggttt gttcattggc attgataatg
    51721 tctaagagct gcctaaagga ggttcttccc aaattttcaa cgttaatatc aaatgttgtt
    51781 aagtaagggt gaatcaattt cgaatagcta gaattattaa aggtaataat cgaaatatca
    51841 tctggcacct taatgtcata aaaggacaag agctggacca ttcgcaccga caaaacatca
    51901 ccaatcacga ttaaggctgt ggccttaaag ctacgtatcg tttcaataac cttttcgatg
    51961 cttattggat cctttcgatc aaataacagc atcggtttgt tttccaagga taatttcaag
    52021 cagcccttga gatagccaat atagcgctca gaagctacct ctgcctccat atcgtctgtg
    52081 ataaacagga tctgtcggtg acccttttga tagagatgat caactgcggt tttagccatt
    52141 agctggttgt cattgtcaat ataggtgatt ttgttctcat caccttctgg tgcgccaaca
    52201 atgacaaaag gaatctggtt ggtcatcaaa tagcctctaa caggatcttc ttgctcagaa
    52261 tataatataa taaagccatc aacacgcttt tgcaggtgca ttaacttaac ctggctcaat
    52321 aaatcctcaa cagacatacc tgttgcaatg gaaacagtga aatgatgttt cttagcttca
    52381 ttggtaatgg tcgatagaat ttccataaaa aagggatcac tcaaacgatc attagtgata
    52441 atcggcggaa aaaccaggcc aatattatgt gtcaggccac tagcaagcat ttgcgcagct
    52501 acattcggaa catagccaag ctcgctcata gctcttctaa ccttttcctt tgtcttttgg
    52561 gagatagatc gattatcctt gaggacacga ctgacggtcg aaggattaac acctgctttt
    52621 aaggcaacgt cttttattgt aaccatataa acctcattta atacctgata atgacgctat
    52681 gtcaggcttt ttcacatgta ttttgctttt attatacaat tatctcctaa aaaatcaact
    52741 ctcgccctgc aagaaggcga cataaaaaac tgctgtcctc atgatcgaaa aaatgttaaa
    52801 aaaatcaact ttttttaaaa aaagactaga ctttttctgt aaacggttgc ataatattaa
    52861 gtgtaagaaa tatatcttag gaggaaatcg ctatgaaatc atggcaaaaa gttatcgtca
    52921 gtggggcaag cttgacactt gctagcgcct tattagtagg gtgtgcatct ggttcaaagg
    52981 acaaaacaga aactgcatca ggtactgatt caaaaacaat taagctttgg gtaccaacag
    53041 gagctaaaaa gtcatacaca gatgttgtcg ctaaatttga aaaggactct ggctacaagg
    53101 ttaaggtgat cgagtcagag gatccaaaag cacaagaaaa aatcaaaaaa gatgcttcta
    53161 ctgctgccga tgtcttttca cttcctcatg accagcttgg tcagctcgta gaatctggca
    53221 ttatccaaga agtcccagag gaatacacta aagagatcgc tgatacagca actgatcaag
    53281 ctatccttgg tgctcaatac aagggtaaaa cctatgcctt cccatttggt attgagtcac
    53341 aggttctctt ctacaacaaa actaagctag ctgctgatga tgttgcttca tacgatacca
    53401 tcacgtctaa ggctaccttc ggtggtacct tcaagcaggc taatgcttat gctactggtc
    53461 cattgttcat gtctgttggt aacacattat ttggtgaaag cggtgaagac actaaaggaa
    53521 ctaactgggg caatgaaaaa ggggttgctg ttcttaaatg gatttcagac caagcctcaa
    53581 acaaaggatt tgttaactta gatgccaaca acgtcatgtc tcagtttgga gacggttcag
    53641 ttgcttcatt tgaatcaggt ccttgggatt acgaggcagc acaaaaggct atcggtaaag
    53701 aaaaccttgg tgttgctgtt tatccaaagg taactatcgg tggcgaaacc gttcaacaaa
    53761 aggccttctt gggagtgaag ctctatgcgg ttaaccaagc tcctgctaag ggagatacca
    53821 agcgtatcgc agccagctac aagcttgctt catacctaac aaatgctgaa agccaagaaa
    53881 accaattcaa gacacgtaac atcgtaccag ctaacaagac cgttcaagct tcagaggctg
    53941 ttcaatcaaa cgagcttgca aaaacagtta tcacaatggg atcttcttca gattatactg
    54001 ttgttatgcc taagcttagt caaatgggta ccttctggac tgaaagtgct gcaatcctta
    54061 gcgatgcctt caatggtaaa atcaaagaag gtgactacct tgctaagcta cagcagtttg
    54121 acaaggacat tgcagcaaca aaataagcta tctcatttat aatactatcc taaacaagta
    54181 cagaggtggg ctattttaac gctatccttt ctactcatct ctaaaggggt ggaactaagc
    54241 atcattattt tttcagggct tagtccactc ctacttgttt ttgatatgac gtaaagcttg
    54301 gtgctactta aatttttaat cgcttaaaga tttaggtaac acttagctat gtggtcgtta
    54361 gcaccaaacg cttatgacca cagcatctga acaagagagt caggtaatcc tactttcttg
    54421 tatcctaaca taaaggagaa catatatgac tcaggcaggc ttagcatctc aggttactgt
    54481 aaaagaggct ttaacaaagg gaagcttcga tattaaacta tccgctatca tcatgggctt
    54541 tgccaatttt gctaataaac aattcgtcaa aggaacactc tttttattga gtgaggtggt
    54601 ctttttcatc gcctttgttt cacaaatcat tcctgctatt ggcggcctca ttaccctagg
    54661 aacacaaaca cagggcatga caaccaaaac tatcgacggt atcagcattc aggttgctgt
    54721 tgatggagac aattcgatgc taatgctgat ttttggctta gcctctctga ttttttgttt
    54781 gttatttgcc tatatttatt ggtgtaacct aaaaagcgcc cgtcacctct acatgctaaa
    54841 gcaagaaggg gcaaaaatcc caagctttaa ggaggatttt gttagtctag caaatggtcg
    54901 tttccatatg accttgatga caattccatt gattggtgtg cttctgttta cggtacttcc
    54961 tttgatctac atgatttgct tagcatttac taactttgat cacaatcacc tcccgccaaa
    55021 gtcacttttt gattgggttg gtctttccaa ttttggtaac gtgttaagtg gtcgtatggc
    55081 aggaaccttc tttcctgttt tctcatggac actgatttgg gctgtctttg ccacagtgac
    55141 taacttcttc tttggtatca ttttagcact cttgattaat accaaaggct taaaattgaa
    55201 aaaaatgtgg cggaccttct ttgtgattac catcgcagtt cctcagttta tttcactgct
    55261 gattatgcga aatctgctaa atgaccaagg tcccttaaat gccctgctta gcaaattagg
    55321 gttaatccac cattctctac cgtttttatc tgatccaatt tgggctaaat tctctattat
    55381 ttttgttaat atgtggatcg gtattccatt taccatgtta atcgcaacag gtatcattat
    55441 gaacctgcca agcgaacaaa ttgaggctgc agagattgat ggggcaagta aattccaggt
    55501 cttcaaatca atcaccttcc ctcaaatcct cattatcatg acaccaaacc tgattcagca
    55561 atttattgga aacatcaata acttcaatgt gatctatctc ttaactggtg gtgggccaac
    55621 caattcagcc tattaccaag ctggaaccac cgatctattg gtgacttggc tctataaatt
    55681 gactgttaca gcagcagatt ataatctagc ctctgttatt ggtatcttaa tctttaccgt
    55741 atcagcaatc tttagcttac tggcttacac aagaactgca tcatacaagg aaggagcagc
    55801 gaaataatga aaaacaaacg tcgatttcag cttggattag tttacgccat tttaaccgtt
    55861 ctctcaatca tttggctttt acctatcgct tgggttgttc tgactagctt tcgtgctgaa
    55921 ggcactgctt atgtcgatta ttttcttccc aagcacctca cattagacca ttatattaag
    55981 ctctttacaa atgaaacatt tccttttggg agatggtttg tcaatacctt tgttgttgct
    56041 atctttacct gtatcatctc aacctttatt acagtggcga tggcttactc gcttagtcgg
    56101 atcaaattca agtttcgcaa tcgtttctta aagcttgcac tagtgctaaa catgtttcca
    56161 ggctttatga gcatgattgc tatctactat atcctaaaag cacttggcct tacgcaaagt
    56221 cttaccgccc tagtccttgt ttattctgcc ggtgctgcac ttggatttta cattgctaag
    56281 ggcttctttg ataccattcc ttattcgctt gacgaatctg ccatgattga tggggctact
    56341 cgtatggata ttttctttaa gattacccta ccgctatcaa agccaatcat tgtttacact
    56401 gcactccttg cctttatggg accttgggtt gactttatct ttgcccaagt gattttagga
    56461 gatgcaacca gcagatatac ggtagctatc ggactctttt caatgctgca gcctgacacc
    56521 atcaatgact ggttcatggc ctttaccgct ggatctgtgt taattgctat tccaatcaca
    56581 ttgctcttta tgtttatgca aaaatactat gtagagggcg ttacaggtgg ttctgtcaaa
    56641 tagcagtaat gatcacgata acccttactc aaaaaatcct tccc
//
LOCUS       DARYUW010000004        55811 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYUW010000004 DARYUW010000000
VERSION     DARYUW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55811
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..374
                     /locus_tag="TVW11_000206"
     CDS             <1..374
                     /locus_tag="TVW11_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1364353.1"
                     /translation="GGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTKN
                     HLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGAV
                     LTGYSLTRGRLSRQKHKRHHE"
     gene            690..931
                     /locus_tag="TVW11_000207"
                     /pseudo
     CDS             690..931
                     /locus_tag="TVW11_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            934..2091
                     /gene="essB"
                     /locus_tag="TVW11_000208"
     CDS             934..2091
                     /gene="essB"
                     /locus_tag="TVW11_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1364354.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2103..6479
                     /gene="essC"
                     /locus_tag="TVW11_000209"
     CDS             2103..6479
                     /gene="essC"
                     /locus_tag="TVW11_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1364355.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6492..6821
                     /locus_tag="TVW11_000210"
     CDS             6492..6821
                     /locus_tag="TVW11_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1364356.1"
                     /translation="MSTVTILPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6825..7259
                     /locus_tag="TVW11_000211"
     CDS             6825..7259
                     /locus_tag="TVW11_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1364357.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7261..7545
                     /locus_tag="TVW11_000212"
     CDS             7261..7545
                     /locus_tag="TVW11_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1364358.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7616..8918)
                     /locus_tag="TVW11_000213"
                     /pseudo
     CDS             complement(7616..8918)
                     /locus_tag="TVW11_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9299..10009
                     /gene="ccdA2"
                     /locus_tag="TVW11_000214"
     CDS             9299..10009
                     /gene="ccdA2"
                     /locus_tag="TVW11_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1364359.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10023..10673
                     /locus_tag="TVW11_000215"
     CDS             10023..10673
                     /locus_tag="TVW11_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1364360.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10691..11803
                     /gene="msrB"
                     /locus_tag="TVW11_000216"
     CDS             10691..11803
                     /gene="msrB"
                     /locus_tag="TVW11_000216"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1364361.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12071..12811
                     /locus_tag="TVW11_000217"
     CDS             12071..12811
                     /locus_tag="TVW11_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1364362.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12808..14526
                     /locus_tag="TVW11_000218"
     CDS             12808..14526
                     /locus_tag="TVW11_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1364363.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HSKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14565..15653
                     /locus_tag="TVW11_000219"
     CDS             14565..15653
                     /locus_tag="TVW11_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1364364.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15668..16372
                     /locus_tag="TVW11_000220"
     CDS             15668..16372
                     /locus_tag="TVW11_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1364365.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16632..17120
                     /locus_tag="TVW11_000221"
     CDS             16632..17120
                     /locus_tag="TVW11_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1364366.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17630..18103)
                     /locus_tag="TVW11_000222"
     CDS             complement(17630..18103)
                     /locus_tag="TVW11_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1364367.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18244..18924
                     /locus_tag="TVW11_000223"
     CDS             18244..18924
                     /locus_tag="TVW11_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1364368.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19194..20429
                     /gene="arcA"
                     /locus_tag="TVW11_000224"
     CDS             19194..20429
                     /gene="arcA"
                     /locus_tag="TVW11_000224"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1364369.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20439..20870
                     /locus_tag="TVW11_000225"
     CDS             20439..20870
                     /locus_tag="TVW11_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364370.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20885..21898
                     /gene="argF"
                     /locus_tag="TVW11_000226"
     CDS             20885..21898
                     /gene="argF"
                     /locus_tag="TVW11_000226"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1364371.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22060..23553
                     /locus_tag="TVW11_000227"
     CDS             22060..23553
                     /locus_tag="TVW11_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1364372.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     IFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23570..24901
                     /locus_tag="TVW11_000228"
     CDS             23570..24901
                     /locus_tag="TVW11_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1364373.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24919..25869
                     /gene="arcC"
                     /locus_tag="TVW11_000229"
     CDS             24919..25869
                     /gene="arcC"
                     /locus_tag="TVW11_000229"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1364374.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26089..27081
                     /locus_tag="TVW11_000230"
                     /pseudo
     CDS             26089..27081
                     /locus_tag="TVW11_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
     gene            27253..27792
                     /gene="rsmD"
                     /locus_tag="TVW11_000231"
     CDS             27253..27792
                     /gene="rsmD"
                     /locus_tag="TVW11_000231"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1364375.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27782..28282
                     /gene="coaD"
                     /locus_tag="TVW11_000232"
     CDS             27782..28282
                     /gene="coaD"
                     /locus_tag="TVW11_000232"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1364376.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28260..29297
                     /locus_tag="TVW11_000233"
     CDS             28260..29297
                     /locus_tag="TVW11_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1364377.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29859..30473
                     /locus_tag="TVW11_000234"
     CDS             29859..30473
                     /locus_tag="TVW11_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1364378.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30477..31559
                     /gene="rlmN"
                     /locus_tag="TVW11_000235"
     CDS             30477..31559
                     /gene="rlmN"
                     /locus_tag="TVW11_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1364379.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32841..33371
                     /locus_tag="TVW11_000236"
     CDS             32841..33371
                     /locus_tag="TVW11_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1364380.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33744..33977
                     /locus_tag="TVW11_000237"
     CDS             33744..33977
                     /locus_tag="TVW11_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1364381.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33952..34923
                     /locus_tag="TVW11_000238"
     CDS             33952..34923
                     /locus_tag="TVW11_000238"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1364382.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34933..35313
                     /locus_tag="TVW11_000239"
     CDS             34933..35313
                     /locus_tag="TVW11_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1364383.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35709..37550
                     /gene="typA"
                     /locus_tag="TVW11_000240"
     CDS             35709..37550
                     /gene="typA"
                     /locus_tag="TVW11_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1364384.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37632..37886
                     /locus_tag="TVW11_000241"
     CDS             37632..37886
                     /locus_tag="TVW11_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1364385.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38032..39393
                     /locus_tag="TVW11_000242"
     CDS             38032..39393
                     /locus_tag="TVW11_000242"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1364386.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39390..40472
                     /locus_tag="TVW11_000243"
     CDS             39390..40472
                     /locus_tag="TVW11_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1364387.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40473..41663
                     /locus_tag="TVW11_000244"
     CDS             40473..41663
                     /locus_tag="TVW11_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1364388.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41875..43239
                     /gene="ftsA"
                     /locus_tag="TVW11_000245"
     CDS             41875..43239
                     /gene="ftsA"
                     /locus_tag="TVW11_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1364389.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43263..44591
                     /gene="ftsZ"
                     /locus_tag="TVW11_000246"
     CDS             43263..44591
                     /gene="ftsZ"
                     /locus_tag="TVW11_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1364390.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44594..45265
                     /locus_tag="TVW11_000247"
     CDS             44594..45265
                     /locus_tag="TVW11_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1364391.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45278..45940
                     /locus_tag="TVW11_000248"
     CDS             45278..45940
                     /locus_tag="TVW11_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1364392.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45945..46202
                     /locus_tag="TVW11_000249"
     CDS             45945..46202
                     /locus_tag="TVW11_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1364393.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46199..46993
                     /locus_tag="TVW11_000250"
     CDS             46199..46993
                     /locus_tag="TVW11_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1364394.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47003..47758
                     /locus_tag="TVW11_000251"
     CDS             47003..47758
                     /locus_tag="TVW11_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1364395.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48029..50827
                     /locus_tag="TVW11_000252"
     CDS             48029..50827
                     /locus_tag="TVW11_000252"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1364396.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51305..51607)
                     /locus_tag="TVW11_000253"
     CDS             complement(51305..51607)
                     /locus_tag="TVW11_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1364397.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51669..52118)
                     /locus_tag="TVW11_000254"
     CDS             complement(51669..52118)
                     /locus_tag="TVW11_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1364398.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52278..54530)
                     /locus_tag="TVW11_000255"
     CDS             complement(52278..54530)
                     /locus_tag="TVW11_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1364399.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54812..55042
                     /locus_tag="TVW11_000256"
     CDS             54812..55042
                     /locus_tag="TVW11_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1364400.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55524..55625)
                     /locus_tag="TVW11_000257"
                     /pseudo
     CDS             complement(55524..55625)
                     /locus_tag="TVW11_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        15890 a        10581 c        13194 g        16146 t
ORIGIN      
        1 aggggggtga gaaaaaagac attagctaca tcgagcaaga gggcgatctg tctgccctat
       61 ttcaatcaga gacagactta agcattaaaa agaaacagca gcatcgaaaa gaaactagtc
      121 agacgaccaa gaatcaccta tttatgactc atattgatag tgacaacctt gttgcaaggt
      181 atcagccact cttatttaac ccagagcagc gtctggcagc aacagatgac cagtatggtg
      241 ttttgctcgc tcaaaaaact atcggcatca cttggcaaat gctggccata cttcttgtgg
      301 gagctgtact gactggctat tctctgacta gagggcgatt atcaaggcaa aaacacaaaa
      361 gacatcacga gtagaatcgt ctgtcaagag tatctactca ctgaaaatag agggctagct
      421 taggagactt cctaatgctg catttataag aaaaggctct cagctgtttt gacagtattg
      481 ggcaaggcct tagggcctgt agcaaatatg aagagcagct ttgatcagca ggtagcaagt
      541 cagtcaatac aaatgcttga aagcctacct gctaagaaaa gtgtgtgttc tacgatactt
      601 tagtgatgtg aatcacctca agaggcttta gctagcttgg caggtgatgt caggtgacat
      661 ggaaacttat caggaaaggg ctaattttta tggagaatta tattagtatc agtcttgatt
      721 gctcgcattt ttttcacagg aatttgattt gcgggtacca aggacaatga cctttaagga
      781 gctattacaa atcgtatcag atgcttatgg tttgggattt caggtggtaa atcccagtgc
      841 tagaaatgag caaggtggtc agctgatgac aagcaccagt cgcatggata ccctaaaaaa
      901 tggtgcactg ttagtattgg aaaatttata aacatggaga aaaagatgaa aacaataata
      961 cgtgagctat tggttgagga tgttaaagga gatgctgagg ttgcttatac cttactagct
     1021 tctgagcatt ctctttttgt tccttccaag ttagaacagg ctttcgacaa gctgattcta
     1081 gaggctagca ttgatgacat gtatgactgg tcagccctag aggcgatgat tgttgaggaa
     1141 aagctaaggc atttgctaaa tcttagtgag ctgtttgatc agctcttgga ctcaaagttc
     1201 acctacagct ttacaccaga taatctggtc tttaaccgta atgcagagcc acagttgatt
     1261 tttcggggaa tcaaggatca ggttcctcct taccagccgc ttgagcgtga ggtctttgtg
     1321 aatacactga aatgtatgac aattgccttg cttgataaaa agaccagcta tgacgctctg
     1381 atgggtggca agcttccctt ttacaaaggc aatctttttt gcgaagcagt ggccaaggct
     1441 gaggcgctgc aggagttgca ggagctttta gcgacaaagt accatgagga gcaaaaagac
     1501 aataaagagc atttttctcg tgttgctaac aagacgatat cgcgcttgaa attgaccacc
     1561 atttgttcat cagtgcttgc tttgttgtct ttggcgggcg ttctttattt tctattgttt
     1621 gctatgcctt atcaggaaat ggttgctagt ctgcgtatgg cttttattaa tcaagactat
     1681 tctaaggtta tcacaacagc gaagcataca gacagtaagg ccttaagcca gggtgataaa
     1741 tatattgtgg cttactctgt cataatgaca gagcctctaa cagacaagca aaaggaggaa
     1801 ttaagtaaaa tatcgaacca gtctaatgaa gattatttac gctattgggt gctgattggt
     1861 caagcaagga tagatgatgc catggatatt gcgagctatc tagacgaccc gcagctcttg
     1921 atgtatggct tgactaagaa gattgatgat gttcagcgag atcctaatct gacagcagag
     1981 gcgcgtacag agcagcttaa cagctataag agcaaattag acgagctcaa aaaggcctac
     2041 ctgacgccta aagaggaaaa agcagcaggc tctagcagtg acaaggagtg acggaggaat
     2101 ttatgacata ccttatttat gacgacaatg cctatcacct ttattcggat accgtttatc
     2161 agttggggcc ttcatcaggg tctgatattt tcctgccctt gctggaggat attaccttat
     2221 cagtggaggg atcaggtgtt gtcctactgg aagagagcta cagcactggt aagcattgtg
     2281 ttgctctttc tgatgaggtt acagtgacct tacttattct tgaagctgtc actaaatacc
     2341 tgctgccaga ctcctcgctt tacatttcag gagagactac cgcagcactt caattgcttg
     2401 attaccctag tgagctggtg ctgaccctag actctgattc tgccagctgc tatagcccgg
     2461 tgtcttatta tctaaatggt aaatggacga aaggcaagca gcctcttaaa gcatctgatg
     2521 aacttgtttt ttcagatggc ttagtgctta gttttcagga tcagctgcta tcgattcagt
     2581 ccttgtatgc tattcagaca gcattgctgc ctcttacaga ggcagtagct gaggatagag
     2641 ccagtgaatt tcatcgttct cctaggatta tcctgcgtga gcctgaggga aaggtgacga
     2701 ttgcttctgt acccacagat gatgaaggga aaagacagtc tttattaaag ctgatcataa
     2761 cgccccttgc gatgattgtc tttacagggc tctcttatgt ctttttccga ggtgggggaa
     2821 tgctcatgat gatgatggga atgtctgtga ttacgattgg aagctccatt cattcttatt
     2881 tttcagataa aaaatggcat aaagaagccc agcagcaaaa aatcaaggat tatctagcct
     2941 acttggatac caagtatgtg gagctagcag gctatcgtga ggagcaaatc gaagcactgc
     3001 tgtatcatta ccctaatatg acgactattc ttgaaatggc acaaaaaaca gatcgccgta
     3061 tttatgagaa ggctccatat cattttgact ttttgaccta ccgcttgggg ctaggtgata
     3121 ctccagccag ctttcacatt gattattcag attctgagct gaccaagcat catgaaaagg
     3181 caaagcaaag ggttcaagag ctgattgctt attatcaggt gacagcacag gtgcctatcc
     3241 aaaatgcgat tgccagtcca atcggttata ttggagcacg caaggtcgtg attgagcagg
     3301 ttcagcagct gatgatgcag atcgctacct tccatagcta tcatgatgta cagtttattc
     3361 ctatttttcg agaagaagag ctgccattgt ggaattggag ccggtggctg cctcatacta
     3421 agctaaaggt gctaaatagt cgtggctttg tttatagtca gcgaacacgt gaccaattgt
     3481 tgacctcgct ttatcagctg atcaaggagc ggcaattaga cagtgagcag gataagggga
     3541 cagaaaagca atacactccg cattatatag tgctgattac tgacatgagc ctcatgcttg
     3601 accacaatat catggaatac atcaatgagg atttgtctca tctaggcatt cattatattt
     3661 ttgttgaaga ggtcattgaa agtctccctg agcatgtcaa aacagttatt gattatcgtg
     3721 gagataagca tgctcagctc attttgcagg aggggctcta cctcaataag gcctttaccc
     3781 cacttcaacc cttatctatg aaggataagg aggtctttgc tagacatatg gcagggatta
     3841 atcacgttga gaccttacgc aatgcgattc caaatagtgt gacctttctt gaaatgtatg
     3901 gcgttaacaa ggtcgaggag cttaatctct taaagcgctg gaaggaaaat gaggcttatc
     3961 agacaatggc tgttccgctt ggggtgcgtg gtcgtgatga catcttgtac ctaaaccttc
     4021 atgaaaaagc ccatggaccg catggcttaa ttgcaggaac gactggatct ggtaaatcag
     4081 agctggttca gtcttatatt ttgtcgctgg cggtgaatta tcacccctat gaggttgcct
     4141 ttttgctgat tgactacaag ggtggtggta tggccaatct ctttgctgat ttaccacatg
     4201 tcgttggaac cattaccaac ctagatggca atcaggccaa tagggctttg gtatcgatta
     4261 aggcagagct gaaaaagcgt cagcggattt tccttgaaaa tgatgtcaat catattgatc
     4321 aatacactaa gctattcaag gaaggacgag ttaaggagcc cctcccacac ctgttaatca
     4381 tcagcgatga atttgcagaa ttaaaggcca atcagccaga atttatggac gagctggtct
     4441 caaccgcccg tattggtcgt tctcttggtg ttaagctcat tttagcaacg caaaagccaa
     4501 gtggtgtcgt taatgaccag atttggtcga atgcgaagtt taaaattgcc ttgaaggttc
     4561 aagatgttgc agattctcgt gaggtgatta aaaccccaga tgcagcagag attactcagg
     4621 ttggtcgtgc ttatctccag gttggaaaca atgaaattta cgagctgttc caaagtgcct
     4681 ggtctggagc agactacaat ccaaaaggac gacataccat tcagcatgag acaacggtct
     4741 atgaaatcac agctaatggt caataccaag cgattaacaa ggaccttagt ggacttgaca
     4801 agaagagaga agcaaaatcc atgccaacag agctagatgc ggttgtagca gaggctcagc
     4861 agctctttga ggacctgcat attccaaagg tggccagtcc ttggctgccg cccctttcag
     4921 aaaaaatcta tgccagtgat ttacagtcca cgcatttcaa ggactattgg ggacagacac
     4981 aggacttgca gcctgttttg attggctatc aggacattcc tgaacgccaa gagcagtccc
     5041 cactctattt tcatatggaa aaggctgggc atatcctctt agtgtctagt cctggctttg
     5101 ggaagtccac cttccttcaa ggctttgctt tagatgtgat gcgaaagcaa acaccagcac
     5161 aggctcattt ttacctctat gattttggga caagtggctt gattgcgctt tctgattttc
     5221 cacatgtggc agattacttt accctagatg agacagacaa gatcatgaaa tcacttcgtt
     5281 atttaagtga agaaatcaag acccgtaagc atgccctatc taaggctaag gcaaccaacc
     5341 tcaatcagta caatcaatta tccaaggata ccttcccggc tctttttgtc atcattgatg
     5401 gctttgatag tgtcatggac gcaccatttg tagatgctgt ctacaatgtc ttaaacgtta
     5461 ttgcgcgtga tggggcttcc ttgggaatgt accttgttgt gaccttatca agacttaata
     5521 ccatgaggct acagctgcag tctaacttta agaccaagct atccctcttc ttgtttgata
     5581 atagtgattt atcaagtgtg gttggtcgct caaatatccc actagatgat atcaagggac
     5641 gagctatcat gaaacgtgac gacattatcc aatttcagat tgccttgcca tatagcagtg
     5701 agtactatac agattatatg gcggaggtaa aaagagaggt cgaggcgatg agggctgttt
     5761 atcaaggtgc tttgccagcg gctattccaa tgctgccaga aaaggttaca ccggatatga
     5821 tagcagccat gtcagactct gctcaggatt ttgtgattgg tttggagcga gaggacgttg
     5881 ttcctgctgg ctttaccttt aaaaagtcaa tactgatggc ctctgatagc ccagcctttg
     5941 tggctaacta ttataagctg cttgattttc agttgcagcg tctggctgac cagtatcgta
     6001 cggttatttt agatcctagt cagcgtattg caaggcaatt ctttgaggat agtcaacgct
     6061 ttagcacagc cttagatgtt ggagacactc taagggctat tgtagaggac tttaaaaagc
     6121 gtcttgcagc acctggtcag gattatcaaa aatggttagt tgtgattcct gatattgcag
     6181 ctacagcgct ggcagcaggg attagcgagg aagactttaa acagcttgtg accgagggca
     6241 gccagtatgg ggtcacgctt atctttgtcg gagcttatca ggatctggtc aataatacct
     6301 atgataattt tgtgaagctt gcaaatcagc tcattgagca ggtcttttta ggcatgcgga
     6361 tcagtgacca aagccataca cgatatgctt atatcagcaa tgagccttca cttagaccga
     6421 cccagggcta tatcctatac ccagaaggct atgactttat tcaattatta gagatttaga
     6481 aaggaacaaa gatgtcaaca gttacgatac ttccacttgg tagtattgtc attttaaagg
     6541 gcaatactaa gaaaatgatg attattgcgc gtgtgatcgc agctccaatc aaaggggagg
     6601 tttaccgctt tgactatggt gcctgcctgt atccggaggg catgatgggg gatagtttga
     6661 tttactttaa tcatgacgat atttttaaga ttattcaaga aggctatgct gatgatgaca
     6721 atgctctgat gttagagacg atagcacagg ctttagcaac aacggacatt ccaaaaggag
     6781 atgtttcagc cttaaacgat agaaagactg ttgaggacta gcttatgggg caagttgact
     6841 acaatcatat caatcagctt caacgtcagg ttgaccagca cagggccagt ctatcaacgg
     6901 ctacagcaga gatagcgtca atagacgaaa agctagagcg cttgcgttgt gccaaggctt
     6961 ctgttggagc gattcaagga gatgttcatc agatcaaggt ctctgtgatg gctaagaggg
     7021 atcagcctga ttggaaggga gaacgcaagg accgcttgat gtcgagctgg gaggagttct
     7081 ctcatgacta tcgccacttt cagctggagc tagatgctta ttacgatgcc atttgtgata
     7141 cgataacacg cttggagaat caaaaatatg agcagcaagg gcttatcggc tggtgtcaga
     7201 gcatgattaa tagcttggga aatgagattg aaaagctatt tcatattagg gagggctagc
     7261 atgtttggtg ttattcaatt atctgaggtt gtgtttgggg cgcatgtgtt aagcctgact
     7321 gctgctaagg ctagcttgtc tgatgtcaaa gctagctttc ccagccatca gtcatcaagt
     7381 aaggtgctag atctgtatca gtcagagttt gaagcactct ctcagcttgt tgctgcctat
     7441 gctaggcttt tggaaaagga tattgccttg attgccgagg ctggtcaaga attagcccta
     7501 acagataagc agttgggaca agctatagga tttaggttac aataggagga gggtatggga
     7561 tataagattc actttgaagc catcagtgcc gcccaacaaa gcactcaaac cacgatcagt
     7621 gcttggggag aaaggtcgtc ttctctttta tgatgttcaa agcaaggtaa atacttttct
     7681 tgaagttgtc aacgtttctg aatccaaaag cattgcgctt gatacctttg ataaatttgt
     7741 tagttgcttc aagcttggcg ttagaataag gcagttcaat ggcattgatg atatagtcgt
     7801 tatagcgtat aaaggtgttt aaagtcgttt tgaaggtgtg attgagatga ggcaaagcat
     7861 cttgacttaa cccaaagaag agctctgtct tcttttcttg caagtgaaaa agaagtcatt
     7921 ggtacagatc ataatagcct tttaactcag ggattcgttt gaaaatctta ttgagacatt
     7981 gtctaggagt taatgtttct ctaaaggtcc tagagtagaa agtattaaga gatagtttcc
     8041 agttatcctt tagactaagc ttccaatagt atttaagagc ccgatattca agagctttct
     8101 tatcaaatgg cttcatgagt tgaatgcgag tttgattgag cgctctactc atgtgctaca
     8161 caatgtggaa gcgatcgaga acaattttag cttttgggag tgaactagtc cagtggacta
     8221 attcagcctg agcttaaaaa tagaagagcg aagggtttaa tgagaggaat gtaacttcct
     8281 gacatatcga cagtaacaac tttgccctta tttctagctt ctttggagta cttaaagaag
     8341 tgatttcgaa tggttgtttg acatctgtta ttgcgaatga taatgatttt cttggtgttg
     8401 aaatcctgag cgataaaggc tagtttgccc ttttgataag agaattcgtt ccaggaaagc
     8461 acctcaggta aggtggtgta atcctcttta aagtgacatt gcttgagctt atgatagacg
     8521 gtagaggtag agatagcgag tttagcagca atatgcgtaa aagcttcttt attgagcaat
     8581 agctgagaga tcttctgtct aactggttca gagatttggc aatttttctt cacgagattg
     8641 gtttcagaga cagctacctt ccgacaggtt tgacattgaa acctgctctt tttcaatcga
     8701 ataaggctag ggaagccacc gatttcgatg aaagggattt tagagggctt ctggaagtca
     8761 tacttaatct gagctctctt acagtgctta cacttaggag gttgatagtc caatgtagcg
     8821 atgacttcga tatgtgtatc atgctggata gccttatcga aggtgatatt ttgatcttta
     8881 attccgatga gtagtgtggt atgatgaatc tgttccataa gacactttct aatgatggtc
     8941 tggtcgcttt tcatgataag ccttatggga ctttttgtgt actcaaaagc cctataatct
     9001 ccatagtgga cttacccact acagaaatta taaagcccta aaaaccaatc tgaggttgtt
     9061 gcaacaggat tggttttttc ttgtgattgc agatcagact tttcaaaaga acaagcacat
     9121 tatctcagct agactggtgc ttgatagctc ctgagccctt gtttgctgta gttgatagga
     9181 ctttgctgat ggcctagtca ggcatatcgt atcaaattca agttttttca tgtcactgtc
     9241 tatagtttgt ctgccctact ttaggtagaa tagaggtaac ttaagagagg agtttattat
     9301 ggaattaacg atgcttttga tggtttcagt tttcattgca gggctgttat cattcttttc
     9361 cccttgtatc tttccagttc tgccggtgta tttaggcatt ttgttagatt ctgatgattc
     9421 taggtctatt actatttttg gcaagaaact atattggtac ggtattgtta agacccttgc
     9481 ttttatttca ggtctatcta ccatttttat cattttaggc tatggggctg gtttactggg
     9541 taatatttta tatgctgctt ggtttcgcta cctacttggt gcctttgtga ttttgttagg
     9601 tattcatcaa atggaaatcg taaccattaa gaagctgcaa tttcaaaaga gcgtagcatt
     9661 tcaaaataag aaggaccgca atgctgtttt aaatgccttt ttgctgggaa ttacctttag
     9721 ctttggttgg acgccctgtg ttggaccagt tcttagctcg gtgcttgcct tagcggcttc
     9781 aggtggcagt ggggcttggc agggtggctt cttgatgatt atttatacct tgggcttagg
     9841 cctaccattt ttactactat cttttgcttc tggtattgtg ttgaagcact ttaataaatt
     9901 aaaaccacac attcctctat tgaagaagtt aggtggctta cttattgtta taatgggctt
     9961 actgttgatg acaggaaatc tcaatagttt atcaggttta tttgaataaa ggagaagaaa
    10021 caatgaaaaa aacaacattt ttaacaacag gcttagcatg tcttgcttta ttaactgcat
    10081 gttcggcgaa ggataaaatg gccatgaatg atagtaaaaa agaccatatg accaggaccg
    10141 atgacaaatc aaagatgaaa aaggatcaaa aagacaagat gtcagacaag aaggatatga
    10201 tgtcagatga caagcacatg tcagatgctg acaaggctag taagaatgat gggcaaatgg
    10261 ctccagattt tgaattaaag agcattgatg gcaagactta tcgtttgtca gattttaaag
    10321 gtaagaaggt ttacttgaaa ttttgggcct catggtgttc tatctgctta tcaaccttag
    10381 gtgatacaca gtcattagct acgatgaagg ataaggattt tgaggtctta accattgttt
    10441 cacctggtca tcagggtgaa aaatccgagg ctgatttcaa aaaatggttt gaaggaacag
    10501 actttaagga tttaccagtc ttgctcgatc cagatggcaa gctgctagag gcttatggtg
    10561 tgagatctta tccaactgaa atttttgttg gcagtgatgg tgttttagct aagaagcata
    10621 ttggttatgc aaagaaatca gagattgaaa aaaccttaaa ggagattaaa taagcaaagg
    10681 aggctgtctc atggaacaca aatggaagtt attgctactc gtttttggag ccttagtatt
    10741 tttaggaggt gttttgatgg tctttcaaag aggctacgct actagctacc ataataatca
    10801 ggtcaagctg cctgccaaag ggacgtctca gctcaagaag actgctaatg ccaagctgcc
    10861 tgagaagaaa aaggagattt accttgcagg aggctgtttc tggggtgtgg aggagtattt
    10921 ttcaaatgtt gatggtgttc tagatgctgt ttctggctat gctaatggta gaggcgacac
    10981 aacctcttat caattgctgc accagacagg acatgctgag acggttcagg ttgtgtatga
    11041 tgctaatcgg attagcttaa aggagcttct tttacactac tttagaatca ttgacccaac
    11101 aagcctcaat aagcagggca atgatcgtgg cagtcagtac cgtacaggca tttattatac
    11161 ggatccatct gatttgacta ctattgatat ggtctttcag gaaaaagctt cggattacaa
    11221 aaagaaaatt gttgtggaaa aagctcccct aaagagcttt accaaggctg aggaatatca
    11281 tcaggattac ctcaagaaaa atcctaatgg ctactgccat attaatgtca acgaggcttc
    11341 atacccagtg attgataaga caaaataccc taagccaagt aaggaagaga ttaaaaagaa
    11401 gctatcaaag gatgaatatc gtgtgaccca aaacaatgaa actgaaaaag ccttttcaaa
    11461 caggtactgg gattcctttg aagcagggat ctatgtagat gtggtcactg gtgagccgct
    11521 gttttcttcc aaggataaat ttgaatcagg ctgtggctgg ccaagcttta gcaggcctat
    11581 tagcccagat gtgctacgct ataagacaga caagagcttc aatatgaacc gtacagaggt
    11641 gagaagccgc tcaggcaatt cccatttagg tcatgtcttt accgatggtc ctaaggatca
    11701 gggtggtctg cgttattgta ttaacagttt atccattcga tttattccaa aggctgaaat
    11761 ggaagctaaa ggctatggtt accttttaac agcagttgat tagaagatta tcctaagatt
    11821 tgttataata agatgaggaa gcacagatgg ttgattatag ttattaagac ctgaagatta
    11881 cttcagtcga tattgctaaa tgtgatcagg ctcatgccct ttagtcttgc ttaagaggta
    11941 gtagctttta aaagagtgat tacgataaga ggcatttgct cagagcttgt cctatttagc
    12001 tcttgtcgag ctatgtgcag agcttgtatg actatggtca ctaagcatta gaaatagtag
    12061 gagaaatggt gtgtactcat tacttattgt tgaagacgaa taccttgtgc gtcagggtat
    12121 tcgttctttg gttgattttg accaatttgc catcgatcgt atagcagagg ctgagaatgg
    12181 tcaggtggct tgggagttgt tccaagaaaa tccttatgac attgttttaa cagatattaa
    12241 tatgccaaag cttaacggca ttcaactggc agagcttata aaggcaaggg ctccaaagac
    12301 tcatcttgtt tttttgacag gttatgatga tttcaattat gccctatctg ccttaaagct
    12361 aggggctgat gactacctgc taaagccatt ttccaaatca gatgttgaag aaatgctcaa
    12421 aaagctaaag cagaaattag aaaagctcaa aaaaacagag gcccttcaaa aactagttga
    12481 taagccgcag caagaaggct cagaaattaa gctagctatc caagagcgtt tagctgattc
    12541 aagcctaacg ctaaagagcc tatcaagcca gttaggcttt agccctaact atctaagtgt
    12601 tttaatcaaa aaggatctag gtttgccttt tcaggattac ttgattcagg agcgtcttaa
    12661 aaaggctaag ctcttattat taacaacgga tttgaaggtt tatgagatag cagagcaggt
    12721 tggctttgag gatattaatt atttttccca gcgctttaag cagttggttg gaatgacacc
    12781 aaggcaatat aaaaaaggag aaggccaatg aagcgctacc ctcttttagt acaattagtg
    12841 agttattttt ttctgattgt gatttcacta atcactattc tgggagtgat ttattatcag
    12901 accagctctc ataatatcag gcagctcatt gaacgcgaaa ccagacagag cattcggcag
    12961 agctctcaat ttattgatgc ctacattaag ccattaaagg agacaacctc agccttagct
    13021 agccatgctg agattcagag ctttgctaag gcagctaaca gtagtcatca agagcaggtg
    13081 ttggcactga tgacaactgt gctgtcgacc aattcagacc tgcgctcagc ggttctggtg
    13141 acaaaggatg gtcgtatggt cacaaccaac ccaaagctaa tcatgactac ctcgcatgat
    13201 atgatggcag agccctggta caagtcagct attgaccgca aggccatgcc ggtgttgacc
    13261 cctgcaaggc agctgtcctc gcattctaaa aaggattggg tggtttcagt tactcaggag
    13321 gtagttgatg agacagggaa caatttaggg gtgctgcgat tggatattgg ctacaatacc
    13381 atcaaatcct ccctagatca attgcagctt gggcgtaggg gctttgcctt tatcgtcaat
    13441 gataagcatg aatttgtcta tcactctaaa aataccgtct atagctcaga gcgagaaatg
    13501 gccgcaatga agccttacct tgctgttgct gatggctata caaagcctaa ggattatttt
    13561 gtttaccaaa gggtgattcc agacagtcaa tggaccttga ttggagttgc ctctttggat
    13621 cagctgtatc atgtgcagcg gcagattttt tggtcctttt tagggacggg tctgcttgca
    13681 actgtcatct gtggtcttgg gacagtattt gttctgagaa gctggattgg tcctatcagg
    13741 aggcttcagg ctctcatttt agctattcaa aagggtaacc gtcagctgcg tgctgaggaa
    13801 attggctcgc ctgagttagc tgatttggca cgtcagttta acgccatgct ggatcaaatt
    13861 gatagtttga tgatttcagt tgctgacaag gaaaaggcta ttgggcagta tcgtctgcaa
    13921 gccttagcca gtcaaattaa tcctcatttt ttgtacaaca ccttagatac tattatttgg
    13981 atggcagagt ttaatgacag ccagcgtgta gttgatgtca ccaagtctct ggctaagtat
    14041 ttccgcttgg ccttaaatca gggaaatgaa ttgattagcc ttgctgatga attggatcac
    14101 gctcgtcagt atttgtttat ccaaaagcag cgctatggtg acaagctgca ctatgagatc
    14161 aaaggtcttg agaaatacca ggactttatg attcctaagc tgattcttca gcccttggtt
    14221 gaaaacgcta tttatcatgg tattaaggag gttgatagac ctggaatgat cagagtaact
    14281 gtattagaag ctgatcgtca tgtgatatta tccgtttggg ataatggaaa gggcataagc
    14341 ttagctgatg acagcagtca ggccctgctt gagtgtggcg gtgttggttt aaaaaatgtt
    14401 gaccagcgct tgaaattaca gtatggtcat ctctatagaa tggcaatcac tagcgagcag
    14461 gctgttttta ctgagattaa gctttatctt cccaagccgc ttgatggcct aaatgagctc
    14521 ccctaatcaa tctgccctta gtagaacaag gaaaagagag gtttatgtct ttagaatccg
    14581 attattttaa gcgaaaaagt cctgtatttg aggcccttat cccttatggc tttacccaag
    14641 agggtgacac ttattgttat caggagtcat ttatggaggg agatttcaag gccttgatta
    14701 cgatcaagtc gtctggtcag ctctcagcta gagtgattga tactgacctt ggggaggact
    14761 atctcccctt gagaaatgat agacagcagg gagtttatgt tggtcaggtt cgtcaagctt
    14821 atctagagct tcttggacgt ttatcagctg cctgctttag gtctacccct tttcagacaa
    14881 ggcaggccaa ccaagtggca acaagcatta gccagcagtg gaatgatcca ctagattacc
    14941 cctttgaaaa attccctaat attgccactt atcgtgtttc tggcaagtgg tatgcgatgg
    15001 tattgcccct gctagccgat aaattaggac aggtgccaaa ggtcttacag gggcaaatgg
    15061 ttgaggtatt gactgttaga attgctccta atcagctaac acacctcttg cagcaacgtg
    15121 gtgtttaccc agcctatcat atgtctaaaa agacctggat tagcctatta ctagatggta
    15181 cactagcaga tgatcagctc tgggagctag tcacgaaaag tcgtcaattg gctaatccta
    15241 atggcctagc taacccagat ggaccagatt actgggtgat tcctgctaat ctcagctatt
    15301 acgatattga cgcggaattt gcagctaatc ctgacattct ctggacgcaa aaggcttcca
    15361 taaaagctgg agactatgtt tttatttata tcactgcacc gaccagatca attcgctatg
    15421 cctgtcaggt cttgagatca gacattccta atcaaggcta tcggaaaaat gcgaagatta
    15481 agaccttaat gtcgctacgc ttgttgcatt gctacgaaga tggtttgatt tcccttgatt
    15541 tgatgaaaca gtatggggtt aatgctgttc gcggtccaag acggttaagc ccacaattag
    15601 ttgcattttt gaaggaaaaa gagtatttta aagatgtgaa acaaaaagaa tgataaggag
    15661 agcgggtatg actcaattta tagcagatca gagcttttgg gaattatttc ctgatgctaa
    15721 gctaggtgtt ttgttgctca ggaactatga caatcaggaa gactccccac aagaggtcaa
    15781 gcaattattg gcagacagcc atgacatagc taagcagtat ttgactgaag agtcgtttag
    15841 tgacaatgag atcattcagg tctatcgtca agcctatcag cgttttaaga caaaaaaggg
    15901 agccagatcc agtattgagg ccctcctaaa gagggtggca aatggtcaag tcctatcctc
    15961 cattaaccct ctggtggata tttacaatac agccagtcta aggtttggtc tgccagttgg
    16021 cgcagaagat agtgattgct ttgtaggtga cttacgcctg acgttaacag agggaggcga
    16081 tgagttttac ctcattggtg attctaaaaa cagtccaact ctgccaaatg agctctgcta
    16141 caaggacgat gctggtgctg tttgccgctg cctaaactgg cgcgatggtg aaaggacaat
    16201 gattaccgat cgcactaaaa atgccttttt agtcattgaa gcattagata gcaagaccca
    16261 agcaagacta caggacgccc ttaagtttat cgaagacaag gctaagtgct acctgaaggc
    16321 agaaacagca ctatatacgc tggatcaagc ctcaccaagt atcacgtttt aatcaaaaaa
    16381 agctaggaag ccagtattcc tagttttttc agttgttcag gtgcttttat ttggtgttgt
    16441 cgagggagat ttccttatag ctgcaagata tgacatgaca gggaaacagt ttttgcttgt
    16501 ttgatctaat caagcgatta ataaaagctt ttaagctgtt ggttatgcta aagggctttc
    16561 ttaatcctat cagagaactt taaaaaatag tataatgtag ttaacttatg atgatagcta
    16621 aggaggtcag catggagtta tttgacaagg ttgatgatac gttaaaggct ttagcgattg
    16681 actaccagct ggttgagcat gagccagctt taaccacaga gcaggcagac cagttcatag
    16741 agggcattga aggggttaga accaagacaa tgtttttaac gaccaggaaa aagaaccatt
    16801 tttatctgat cattatggat gatactaaga gactggatat gaatcgcttc aaggagcttg
    16861 ttggagaaaa gcagattaaa atggcatcag cagaatgctt gcttgccaag atgcagctgc
    16921 caccaggagt tgtttctcct tttggtcttt taaacaacga ggataaggat attcaggttt
    16981 acgttgataa agctattgct cacgaagcta gaatgagctt tcacccaaat accaatgaca
    17041 aaaccatctt tattcaaaca gatgacctct ttaagtttct agcggctata ggttacgcgg
    17101 tcaatatcgt ggatctatag ctaaattcaa ggttcttcta gcggttcttg ctcacatcag
    17161 ttcacaaagc tggtggccta gccaatccag ggcaaacaaa aagcacaata gcctttcttg
    17221 actactgaga atagccagta gacccttgtg tcatatgctt atctggtatt tgagcttaaa
    17281 tctcaaggct tttaagtaga ggatcaaaca aagaaaacga ccagcagacc ttgcgtgatg
    17341 actgattatc aagtctggta ggagctaaaa tcagtcatgg tcttgaggcc taaaacgtcc
    17401 catttgtcgc tcctgttgct agggcattag ttgacatgta tacccacgac taaccaagcc
    17461 gaggagagct gtcgctccct tctcaggagc gtggattgaa atgcaaaagg gatctgatag
    17521 acatttctgc ttttaaagct agtccatcaa aaaaacgcat gacaccactg tagtgggaca
    17581 tcatgcgttt ttgctaagct aaagtgattt gacgcttcct ttgaaagggt tatttattgc
    17641 tgaagaaaaa gggtggtgtg taatggctca ggatttcaaa gcaagctttg gcctgctcat
    17701 tgtcctcaca gataatcaga caggtatcat caccacagat agtggctacg atttctgaga
    17761 tttgcatagc atcaaggata gagccaaagg attgtgccag ccctggtaag gtttttaaaa
    17821 taatctgatg ctgaacaacc ctgagcatga caagggcgtc ctccatataa aagcgcaaac
    17881 gatgctccca acgcgtctga gaaatggcca gcgcttcata atgcgtgtca ttaccagttg
    17941 taaccttgac aaggttaagc tctttcatat cacgtgataa ggttgcctgt gtgatgctta
    18001 tcccattttt tcgtaagcgt tcctgtaatt cctgctgtgt gtgaatagtt gtttcagaaa
    18061 ttagagatcg aattaattga tgacgtgttt cttttttatt catttcttat aatattcccc
    18121 taatgattag taacattcag agtataacaa aaagatggca gtgtgtaaag ttttagatga
    18181 accgcttaca aaaatagcct ttttatgtta aaataaaacg ggtgcttaga aaaggagatt
    18241 tgcgtgattc gaagagaaga ttatcaatac cttagaaaac ttgatgattt ctgtcatttt
    18301 tcaattgaac aatttgacaa gattgtcggc caaatggaat ttagacaagc taaaaaggat
    18361 catatgttat tttttgaagg tgataagagg gacagactct ttttagtgac ctcaggttat
    18421 tttaagattg agcagtcaga tcggacagga acctttacct atactgattt catacgacat
    18481 gggacaattt ttccctacgg ggggctgttt acagatgact actatcattt ttcggtggtt
    18541 gcgatgacag atgtcaccta cttttatttc ccgactgatt tgtttgagga ctattccttg
    18601 cacaatcagc agcagatgaa gcatctctac agtaaaatgt cgtccttgct ggagcttcat
    18661 gagctcaagg tgcgcaatct catcacctcc agtgcaagct cacgtgtgat tcaatccttg
    18721 gctattttac tggttgaaat gggaaaggat agcgatactc tgccttttca gctgacgact
    18781 actgacattg cacaaatgag tggaacaacc agagaaaccg ttagtcatgt ctttagagat
    18841 ttgaaaaagg aaggcttgat tgcagtcaag gggaaatacc tcacctacct agataaaaac
    18901 tattttctgc agtacacaac ctaagatcaa gtcaaaaggc ttcgcttaaa aagttttttg
    18961 acttttttca atttataaat ataagatttt tcgttaaaat gtaaaaaaac aaacaagaaa
    19021 acgtatacaa aaacataaac attcattttc aggcgaaaaa gtgtaatcgt ttacacagat
    19081 tggctgtgag aaatacccta tttttgaatg ctgcttggag taaactaggg gtgtaagcaa
    19141 aagctaagag tcttagcagt gaattcacaa aacattagaa agaggtaatt cttatgactg
    19201 ctcaaacacc gattcatgtt tactctgaaa ttggcaagct gaaaaaggtt ttgctccata
    19261 ggcctggcaa ggaaattgaa aacctgatgc cagactactt ggaacgtcta ttatttgacg
    19321 atattccatt tttggaggac gctcaaaaag agcatgatgc ttttgcacaa gcattacgag
    19381 atgaaggcgt agaggtgcta taccttgaaa cactagctgc tgaatcactt gtaacaccag
    19441 aaattcgtga agccttcatt gatgaatacc taagcgaagc taatattcgt ggaagggcaa
    19501 ctaaaaaagc tattcgtgag ctactgatgt ctattgaaga caatcaggaa ttgattgaaa
    19561 aaacaatggc aggtgtgcaa aaatcagaat tgcctgagat tccagcagca gaaaaaggct
    19621 tgactgactt ggttgaatca agctatcctt ttgcgattga cccaatgcca aacctttatt
    19681 tcacacgtga tccgtttgca actattggta caggtgtttc gcttaaccac atgttctcag
    19741 aaacacgcaa tcgtgaaaca atctatggta agtacatttt cacacatcac ccaatctacg
    19801 gtggcggcaa ggtacctatg gtttatgacc gtaacgaaac cactcgtatc gagggtggag
    19861 atgagctggt tctttcaaaa gatgtgcttg cagtaggtat ctcacagcgg acagacgcag
    19921 catcaattga aaagctcttg gttaacatct ttaaacaaaa tcttggcttc aagaaggttt
    19981 tggcctttga atttgctaac aatcgtaaat tcatgcacct agataccgtc tttacaatgg
    20041 tggattatga taagttcacg attcacccag aaatcgaagg agatcttcgc gtttactcag
    20101 tgacctatga aaatgaagag cttcgtattg tagaagaaac tggtgatttg gctgagcttt
    20161 tagctgctaa tctgggagtt gagcgtgttg agcttattcg ctgtggtggt gataaccttg
    20221 tggcagctgg tcgtgagcaa tggaacgacg gctcaaacac gctaacaatc gcaccaggtg
    20281 tcgtggttgt ttataaccgt aacactatta cgaatgccat tcttgaatca aagggcttga
    20341 agctcattaa gattcatgga agtgaattgg ttcgcggtcg tggtggacct cgttgcatgt
    20401 caatgccgtt tgaacgtgaa gacatctagg agaggcaaat gacaagggtt attgttggaa
    20461 atcagccttt tcaacgggca gctagcttat atattcgcta tcaggttttt gtcttagaac
    20521 ggcagattga tcggcaagat gaatttgatt gcttcgacga taacgatcgc gtgtatgcag
    20581 tcttgtatga tggtgatcag cctgtatcca cagctcgctt tttacccaca gctaaagatc
    20641 aggctcgtct aacaagagtt gctacgctgc gtcagtatcg tggtaggggc tatggtgcgc
    20701 aggtgataga agcgcttgag cagtatgcca gagagcaagc ttacgagcga ttggttattc
    20761 atagcgagat tagcgcacag tcattttatg aaggtcttgg ctatcaagcc tttggcgagc
    20821 cttatgatga agacggtgag ccttgtcaat cagtagaaaa atatttataa aaaggagaat
    20881 ttaaatgaca caagtatttc aaggacgtag cttcttagca gaaaaagact ttacacgtga
    20941 ggaatttgaa tacctcattg attttgcagc acacttgaaa gaccttaaaa agcgtggtat
    21001 tccacatcac tatttagaag gtaaaaatat tgccctcttg tttgaaaaaa catcaacgcg
    21061 cacacgtgct gcctttacaa ctgcggcgat tgatttagga gctcatcctg aataccttgg
    21121 cgctaacgat attcagcttg gtaaaaagga atcaacagag gacacagcta aggtattggg
    21181 tcgtatgttt gatgggattg aattccgtgg ctttagccaa cgtatggttg aagaattggc
    21241 agaattctca ggtgttccag tgtggaatgg cttgactgat gaatggcacc caacccaaat
    21301 gcttgcggac taccttactg tcaaggaaaa ctttggtaag cttgaaggct tgaccttggt
    21361 ttactgtggt gatggacgca acaacgttgc taattcactg ttagtagcag gtaccttact
    21421 aggtgtgaat gttcatatct tctcaccaaa agagctcttc ccagcagaag acatcgtgaa
    21481 gctggctgag ggctatgcta aagcatcagg tgcgcatgtg ttagttactg acaatgctga
    21541 tgaggctgta aagggcgcag atgtgcttta cactgatgtg tgggtgtcaa tgggtgaaga
    21601 agacaagttt gaagagcgtg tgaagctctt gaagccatat caagtgaaca tggagcttgt
    21661 taaaaaagcc gccaacgaca accttatctt cttacattgc ttgccagcct tccatgacac
    21721 aaatactgtt tacggaaaag acgttgctga gaaatttggt gtagaagaaa tggaagtaac
    21781 agatgaggtc ttccgcagca aatacgctcg tcactttgac caagcagaaa accgtatgca
    21841 cactattaaa gcggttatgg ccgcaactct tggtaatctt ttcattccaa aagtgtaagc
    21901 tgtgattggt accttttaat ttattttagc tcatttcatt aatttaacat ttaactacta
    21961 aaaaacgtac tttaactaca tgacgagtcg ttctggttct cgtgtccttg accggaactg
    22021 ggacggctta tttttatgaa aaggtaagag gtaatcacta tgacagaaga aaaaaaacga
    22081 ggttttaaaa ttccttcttc ttacactgtt ttgtttatca tcattgctat tatggcagta
    22141 ttaacctggt ttattccagc tggtgcttat gagactgcta aggatggcgg tgtgatttca
    22201 gggacctacc aaacggttaa gtcaaaccct cagggctttt ttgacatttt aatggcacct
    22261 gttcgaggca tgctaggtgt caaagggact gaaggggcaa ttcaggtttc tttctttatt
    22321 ttgatggttg gtggcttttt aagggttgtc aacaagacag gtgcgcttga tacagggatt
    22381 gcttctgttg tgcgtaaaaa taagggtaga gaaaagctgc ttattgcgat tttgattcct
    22441 ttgtttgcac ttggtggcac aacctacgga atgggagaag aaacaatggc gttttaccct
    22501 cttcttattc cggtaatgat tgcggttggc tttgatagca ttgttgcagt agctattatc
    22561 ctgattggtt cacagattgg ctgtttggcc tcaaccatca atccctttgc tactggagtg
    22621 gcagcagatg cagccggtgt tagtatcgca gatggtatga tttggcggat tatccaatgg
    22681 gttgtccttg ttggtatgtc tatctggttt gtttacagtt acgctagcaa gattgaaaaa
    22741 gacccaagca agtccttggt tgctgacaaa gctgaagaac ataaggaatt cttccagctg
    22801 caaaattccg gtgaggattt gactagtcgt caacgaaagg ttttagccat ttttaccttg
    22861 acatttgtca tcatgattct tagcttgatt ccttgggaag attttgacat tcaattattt
    22921 acaaatatca acacttggct aacaacaaca cctgttttag gtggtattat tggtaaaaca
    22981 atgggagcct ttggtacttg gtatttccca gaaattacca tgctctttat catgatgggt
    23041 gttttagtgg ctgttgttta tcgcatgagt gaagatgact tcttctcagc ctttctaagt
    23101 ggtgcaggtg agttcctcgg tgttgcgatt atttgtgcgg tagcgcgtgg tatccaagtg
    23161 atcatgaatg gtggtatgat tacagcaacc attcttcatt ggggtgaaac aggtcttgca
    23221 ggcttgtcat cacagatctt tgttgtcttg gcctatattt tctatttgcc aatgtccttc
    23281 ttgattccat caacatcagg acttgccggt gcaacaatgg gaatcatggc tccgcttgga
    23341 caattctcaa atgttcctgc tcatttggtt atcacagcct tccaatcagc atcaggtatc
    23401 ttaaacatga tttcaccaac ctctgctatt gttatgggag cgctcgcact tggacgtatt
    23461 gatctaggta cttggtggaa atttatcggc aagtttatcg ttatggtaat gcttgttagt
    23521 gttttgttgt tagtagtagc gacattcttt taagagatag gaggctccta tggaaaccta
    23581 tatccaacca agacaccaag aggcttgtgt agccgcgatt aaaaaaatag tatcttaccc
    23641 ttctgtgcta aatgaggggg aaaatgacac accctttggc caagccattc aagatgttct
    23701 tgaagcaacc ttagccctgt gccaagatct tggttttaat acctatattg atcctaaagg
    23761 ctattatggc tatgctgaat tgggcgatca aacagaggtg cttgctatcc tttgtcactt
    23821 agatgtggtg cctgctggtg atttgaagct gtggcataaa gatcccttta cttgtattga
    23881 aaaagatggc tgcttgtatg gacgtggcac tcaagatgac aaggggccat cgatgatggc
    23941 actctttgcc actaaagcac ttatggacgc tggtgtggtc tttaacaaac gcattcgctt
    24001 tatctttgga acagacgaag aaaccctctg gcgctgtatg aaccgttata atgaagtaga
    24061 ggaggaggca acctttggtt ttgccccaga ctcaagcttc ccattgacct atgctgaaaa
    24121 ggggctttta caagctaagc tagttggtaa gggatcgcct aaactcaatc ttgaggtggg
    24181 tcaggcctat aatgtcgttc cagctagagc ctcttatcag ggagacaagt tggaggcatt
    24241 aaaggaagag cttgacaggc ttggctttga atatgttgtc aaagatgacg agctaaccgt
    24301 ctatggactt gctcagcatg ccaaggacgc tccagatggg attaatgccc ttatcaggct
    24361 tgcaaaggct cttgtagtgc ttgagccaga gccagtcctt gactttcttg ctcatgtggt
    24421 tgatgaagac ggcagagcag tcaatatttt tggtccagtt caggacgagc catcaggagg
    24481 gcttagcttc aacgtagctg gtcttacctt aacaaaagag atgacagaga ttcgtttgga
    24541 cattcggatt ccggtcttag cagataaaga taccttagta gaccagttaa gccaaaaagc
    24601 gcaggactac ggtctagctt acgaggaatt tgattatttg gcacccttat atgtgccctt
    24661 ggacagcgag ctagtaacta ccctgttaga ggtatatcgt aaaaaaacag gggaccaatc
    24721 gccagcccaa tcatcaggtg gagcaacctt tgctcgtaca atggctaatt gtgtggcctt
    24781 tggagcatta tttcctgatg ctgttcaaac agaacaccaa gaaaatgaac atatcgtctt
    24841 agcagatgcc tatcgtgcaa tggatattta cgcggaagcc atctaccgac taacacgata
    24901 agatgaggag tatcatatat gacaaaacaa aaaattgttg tcgcacttgg aggaaatgca
    24961 atcctctcaa cagacgcgtc agctaaggca caacaagagg ccttggtttc gacatcaaaa
    25021 tcactagtga agttaatcaa agaaggccat gaggtgatta tcacgcatgg caatggtccg
    25081 caggttggta atctcttatt gcagcaggca gcagctgatt ctgagaaaaa tccagccatg
    25141 ccattagata cctgcgttgc catgacagaa ggcagcattg gcttttggtt agtcaacgcc
    25201 ctagacaatg agctgcaagc ccaaggcatc acaaaggaag tggcagcagt tgtcacccag
    25261 gtcattgttg atgaaaatga ccctgccttt aaaaatccga ctaaaccaat tggtcctttc
    25321 ttaaccgaag aagacgctaa aaagcaaatg gcagaatcag gtgctagctt taaggaggac
    25381 gctggtcgtg gctggcgtaa ggtggtgcca tcaccaaagc caattggtat caaagaagct
    25441 aatgtgatta gaagcttagt tgattctggt gttgtggtgg tcagtgctgg tggtggcggt
    25501 gtgccagttg ttaaagaccc tgcaagtaaa acgcttaccg gtgtggaagc tgttattgat
    25561 aaagactttg ctagccaaac cctttcagaa ttggttgacg ctgatctctt tattgtcttg
    25621 acaggtgttg ataatgtcta tgttaacttt aacaagcctg atcaaagaaa attggaagag
    25681 gtaacggttt ctcaaatgaa ggaatacatc gctcaggacc aatttgctcc cggaagcatg
    25741 ctgcctaagg tggaggctgc aattgctttt gtggaaaaca aatcaaatgc caaagctatc
    25801 atcacatcgt tagaaaatat tgacaatgtt ctctcagcaa atgctggtac acaaattatc
    25861 gcaggctaat tcagatgact gcacaatgag cttaggcttt tgtgctttga taggttttag
    25921 ctgataagct tgaaaaattg atttaaaagg ttaaattagg ttaatttagc cttttctttt
    25981 acttttaatc ggtgtataat aagcgtaata tttttttatt tttactcatg attagaatgg
    26041 taaaaaataa aggtgactta gtcgcgaaaa tgatttaaag gaggagctat gaaaaaaagc
    26101 tttattcatc aacaagagga aatttccttt gttaaaaata catttacgca gtatttgatt
    26161 gctaagcttg atgttgttga ggtgcaaggt cctattttaa gtagggtcgg agacggcatg
    26221 caggacaatt tatctggggt tgaaaatccg gtatctgtcc atgtcttgaa cattcctaat
    26281 gcaacctttg aggtggtgca ttcgctagca aaatggaagc gtcatacctt agcacgtttt
    26341 ggctttaatg aaggtgaagg tcttgtggtg aatatgaaag cgctccgtcc tgatgaagat
    26401 tcgctagacc agacgcattc agtgtatgtg gaccagtggg attgggagaa ggttatccct
    26461 gatggtcagc gcaatctagc ttacctcaaa gaaactgtcg aaacgattta caaggttatc
    26521 cgcttgacag agctagctgt tgaggcacgc tatgatattg aagctgtctt gccaaagaaa
    26581 attaccttca ttcacaccga ggagcttgtt gccagatacc ctgatttgac accaaaggag
    26641 cgtgaaaatg ctatcacaaa agaatttgat gcggtatttt tgattggtat tggcggtgta
    26701 ttgccagatg gcaagccaca tgacggtcgt gcgccagact atgatgactg gaccagtgag
    26761 tcagaaaatg gctaccatgg cttaaatggt gatattctcg tttggaatga gtagctaggc
    26821 acagcctttg agctattctc aatgggaatt cgtgttgatg aagaggctct aaagcgtcag
    26881 gtggacatta ctggagatca ggaacgccta caatttgatt ggcacaaatc gctgctaaat
    26941 ggtctgttcc ccctaaccat cggtggagga attggtcaat cgcgtatggc catgtttttg
    27001 cttcgtaaaa agcacattgg agaggtccaa acatcggtgt ggccacaaga ggttcgcgat
    27061 acctacgaca atattttata gatgatacgg aggctaggtt tttacctata gcctctattt
    27121 ttgtccctaa gtgatgcttc attagagctc atttagtgct aagcaggctc gtcagttata
    27181 taataggtca aaaatttgaa aaaatgaatc atttttaagg cttgacacta gatttttgtt
    27241 ataatatcag ttatgagaat tgtatcaggt gaatttggag ggcgtcccct aaaaacgctc
    27301 gaaggcaaga ctactcgacc cacatcagat aaggtacgtg gcgcgatttt taatatgatt
    27361 ggtccttatt ttaagggcgg acgtgtctta gacttgtttg ctggatcagg tggcctatca
    27421 atagaggcta tttctagggg catgtcagag gcagtgctgg ttgagcgtga tcgtaaggcg
    27481 caagccatta tccaagccaa tattaagatg acaaaagcta gccagcaatt tacgctatta
    27541 aaaatgaacg ctgagcgtgc acttgatcac ttatccggtc agtttgatgt ggtgtttttg
    27601 gacccacctt atgctaagga aacgatagta gccaatatag aggccttggt ggagaaaaat
    27661 cttttaagcg acgatgtgat gattgtttgt gagacggatc ggtcggtagc tctgccagag
    27721 gcaattgcct ggctagggat ctggaaagaa aaacaatatg gaattagcaa ggtaacagta
    27781 tatgtcaggt aagattggac tttatacagg gtcatttgac ccagtgacaa atggacacat
    27841 ggatatgatt aagcgtgcta gccatttgtt tgagcatgtt tatgtcggga tttttaacaa
    27901 tccaaataag cagagctttt ttacttttga gctgcgagct caaatgctaa gcgaagcggt
    27961 ttgtgccttg ccaaatgtga cagtggtttc tgccgagcat ggtcttgcag ttgacctggc
    28021 tagggagctg tctgtgaccc accttatccg agggcttcgc aatacagctg attttgacta
    28081 tgagataggc ttagagtatt ttaatcatag actagcccct gatattgaga ccatttacct
    28141 gatggcgact catgacctgc agcccgttag ctccagtcgt atcagagagt tgattgcatt
    28201 tagagcgcca attactggtt tggttccgca ggctgttatt aatcaagtgg agaaaatgaa
    28261 tgaaaacaat aaaaaaaatt aaatggtggc tgattggctt tgttgccttg ctttttctac
    28321 tgttgacact gtttttcccc ttgccttatt atattgaaat gccaggtgga gcctatgata
    28381 ttcgctcggt attgactgtc aatggcaaag aggataagga aaagggagct tatcagtttg
    28441 ttgtagtgag cctcagtcgg gccaccttgg ctaaattgct ctatgcttgg ctaacgcctt
    28501 tcactgagat tagcaccatg gaagatacta ctggtggcta tagcgatgct gactacctgc
    28561 gaattaatcg cttttatatg gaaacctctc aaaacagcgc tgtttatcag gcccttactc
    28621 tagcaggcaa ggaggtaagc tttgattata agggtgttta tgtcttagac gtcagcaagg
    28681 attctagctt taaaggtgtg ctgcacctag cagatacagt gacaggtgtc aatggtaaaa
    28741 catttacaac gtctgccgat ctgattgatt atgtttctca tttgaccttg ggagatgagg
    28801 tgcaggtaca atttacaacc gctggtgagt caaagactga aaaaggaaag attattaagc
    28861 ttaaaaacgg taaaaatggg attggcatta ccctgacaga ccacacacag gtcatttctg
    28921 gtgatgaggt cgactttagc actggaggtg tgggtggacc aagtgcaggc ttgatgttta
    28981 ctcttgatat ttatgatcaa atcaatcacg aagacttgcg caagggacgt gtgattgctg
    29041 gtacaggaac cattggcaag gatggaaaag ttggagatat tggcggggcg ggcctaaagg
    29101 tggctgccgc cgccgctgct ggtgctgata ttttctttgt tccaaataat cctgtgcata
    29161 aggacgtcaa aaaagcaaat cctaaggcta ttagcaatta cgaggaggct aaaaaagcag
    29221 ctaaacgact aaagacagca atgaaaatta ttcctgtgaa aaccgttcaa gatgctataa
    29281 gctaccttaa aaaatagaag caatgcgaag caggctaata gggcatgctc tgtcttgctt
    29341 ctagttggtg gaatttagct agctcaaagg tcttgagacc taagcataag gtctagacag
    29401 tattctagag ctagacctta tgcttgatcc tgaacaagga agaccgccaa agaagaacaa
    29461 aatcctcagg ccaaaagagc ccgtagggaa atattgccat tatctatcaa ggctttttga
    29521 agaaaatcac ttaaagacag tagggcgtta ggctttactg tcttagtttt tcttgcctga
    29581 agtcatggct gctgatgatg ttacatcaag gcttactagc cagcagagca caaggagcag
    29641 ctttggctta ggtttatttt ctctgctgac tagtaaagaa ggttgctgtc agtctgctta
    29701 caaaaaccta aaaatagtgt ataataggta ggctatgggc tgtcaggagt cgctagcctg
    29761 cttacccaga ccagcccttt gagaagagca agcatggctc ttctcagaat aacccaggat
    29821 taacagacat caaaattaat gctaaggaaa ggagctatat gaaaagagat attttaccag
    29881 agatgtataa ttacaataaa tttcccggtc cggaatttat tcattttgat cattatgtca
    29941 aggctgaagg cattgagtta ttgctgctga aaaatgaaaa aaatgctttt aacacaacga
    30001 gctttggtca gcgcttcaca gagatattat taaagtatga ctatattgtt ggagattggg
    30061 gcaatgaaca gctgcgtctc aagggctttt acaaggatca tcatgatgtc aaaaaagcta
    30121 gtcgtatttc tcgcctagaa gactatatta aagaattttg taactttggc tgtgcctatt
    30181 ttgttttgga aaaccctaat cccaaggaca tgccaaaaga ggaggaaagg ccatcaaggc
    30241 gcaggaaatc gtctaaagcc aatcgccgca gaaatcagcc tcagcatagt cagcaggcac
    30301 ctgctaaaga caacttcaaa aagctaacca aggataggtc agcggacaag ccaagcttta
    30361 ccagcaaaaa gcgcccagct cctaataaga ccaagggaaa ccaaaggcgc tctcgtacta
    30421 gtcaactgaa ccataaaacg gatcacttta tcatcagaaa gaaggacaat taatctatga
    30481 aaccatcaat ctatggccta acgcgcgacg agctaattgc ttgggcgatt gacaatggtc
    30541 aaaaggcatt cagagcgaca cagatttggg actggcttta cagaaaacgg gttcaatcct
    30601 ttgatgaaat gactaacatt tctaaggaat ttgttgccat tctaaaggac agcttttgta
    30661 ttaatccctt gaagcagcgt gttgctcagg aatcagctga tggaacggtt aagtatttgt
    30721 ttgaattgcc agatggtatg ctgattgaaa cggttttgat gcgtcagcac tatgggcagt
    30781 cggtctgtgt aactacgcag gttggctgta atataggctg caccttctgc gctagtggct
    30841 tgattaaaaa gcaacgggat ttaaacagtg gtgaaatcac tgcacaaatt atgatggtgc
    30901 aaaactattt tgataagcgt gctcaagacg aacgtgtcag ccatgttgtt gtgatgggga
    30961 ttggagagcc ctttgataat tatcaaaatg tgatgacctt tcttcggacg atcaatgatg
    31021 atcatgggct tgctattggt gctcgtcaca ttactgtttc aacctcaggc ttggctcaca
    31081 agattcgtga atttgccaat gaaggagtcc aagttaatct ggctgtgtca ctgcatgcac
    31141 ctaataatga gctgcgctca agtatcatga ggatcaatcg ttccttccca cttgataagc
    31201 tcttttcagc aatcgaatat tacattgaaa caactaatcg tcgtgtgacc tttgagtata
    31261 tcatgcttaa taaggttaat gatggggtag agcaggcaca ggaattggca gatttgacca
    31321 aaaggattcg caagctgtct tatgttaacc tgattcccta taatcctgtc tcagagcatg
    31381 accaatacag tagaagtcct aaggagcgtg tggcagcctt ttatgacatt ctaaagaaaa
    31441 atggagtgaa ctgtgtcgtt cgtcaggagc atggtacaga tattgatgct gcctgcggtc
    31501 agctgcgctc taataccatg aaaaaggacc gacaaaaagc agcagctgca aggacatgat
    31561 gacttggtca aggttgctga tttgattgat aggagatgga gataaaaatc tgacctcaaa
    31621 taaagcaaac aaataggtct agttttctga gatcccgaaa gcaggtcttg ttcgtttttt
    31681 aatgaatgag actaggtcat aaagtacatg cgttaagaat gtctaaagtg cagctctttt
    31741 tgtcccagcc tccctctttt atcttggtag cagttgtcaa gtaattgcta agcaacagtg
    31801 ttttatcttt attggctgta aaaaaagata tagtgccttt attcacacct tttctgaatc
    31861 acttgagcct tgttctgacc gctccttttg gtgcttctga tccatatagc ctaagctttt
    31921 cagagctatg aatcgaggca aaataatagg tgttagccct agctgcttga tgtagctagg
    31981 gcttttgtga cctagctgcc agtgagcctt tcaaatagca atatggctat aaggcccagt
    32041 gtcagatagg gaataaaagg gattttctta gtttgtagaa gtaggcaggc tagaattccg
    32101 atcagactgg caatttggac gatccataac aaagagctaa gcttgaccac aagagcaaga
    32161 ttagctaggt aaagaaaatc tccggcacca atattgatag gaaaagctac gcttagcagt
    32221 gcaagcaaaa gcaatagcac tgttaacagg ttaatgctat aaaatggcag cagaaacaaa
    32281 aagctcatca gccagatgag caaaggatac tcttgactgt ctaaatcaaa aaagcacagt
    32341 agcaaagaga agcataggag ataaagctgt gtccaggtca agccgcaaag ggcagccagt
    32401 ccgaaaatga ggctggtgat tatttctaaa taaggaagca taacccagtg cttttgttca
    32461 tgcttagagt tgtaagtggg ctttgccata ggaaaaaaga ggcttgaaag atgaagttga
    32521 cctatataga gcttgaccca agcctttgct tgctgttcag aaaacaggtt aagtattagc
    32581 cgaaagaggt ttcccacaag aaaaccacaa tagcaataaa aaatagtgtt catacttatt
    32641 tatccgaaaa acaatttaaa ttcttgcaat attttaaaaa acggtgtaca atgaaactat
    32701 aaaacgagaa tgattctaaa taagctgttg atacttatct gaattggctc gttatcgtcg
    32761 aatggagctg acaagagagt gacttttctt gctgcatacc attcatgccc ttttatatct
    32821 atcagtaagg agagtttatt atgacaaaca cactcgttga aaacatttat gcatcagtaa
    32881 ctcataatat ttctaaaaaa gaagcatcaa aaaatgaaaa aaccaaggct gttttaaatc
    32941 aagcagtagc agatctatct gtagcagctt caattgttca tcaggttcat tggtacatgc
    33001 gtggtcctgg ctttttatac ctgcacccta agatggatga gctattagac cgcttgaacg
    33061 cgaacctaga tgagatgagt gagcgcttga ttactattgg tggggcaccc tactcaaccc
    33121 tagaggagtt ttcacagcat tctaagctag atgaaacaaa gggaagctat gataagtcag
    33181 tagctcagca tttagctcgt ttggtagagg tttaccttta ccttaccagt ctttatcagg
    33241 ttggtttaga cattactgat gaagagggtg atgctgcttc aaatgatttg ttcacagcag
    33301 caaaggctga cgctgaaaag actatttgga tgctacaggc agagcgtggt caaggtcctg
    33361 ctattttcta aagcgtcata caactgatat aacataaaaa aggcagagcg tggtatagcc
    33421 ctgtcttttt aacgccttta aagtcagcta ttagtgctag tgatgtcagg tctcacagct
    33481 tttttatgat ggatgaccaa catttttaga ccttgtcacc acagcagagc atgtggcatt
    33541 tagtccacct tgggctcacg tcgatggtct tacttatgat atatcaaggc ttgtgacatt
    33601 accgttgcct tttatcttca gtctgagctg ctggttccta ctgctgatgc tgcttgatag
    33661 tgttatagtg attttcagaa atatggaaag cgattgcata attgtcttga aatctcatgc
    33721 gtaatttgct aaaatctagt tatatgaaaa cattatacga tgtacagcag ctgttaaaag
    33781 gctttggtat tgttatctac atgggaaagc ggctttatga tattgaaatg atgaaaatag
    33841 agctgcaaag gctatatgat ggtggcttgt tggataaaca ggcttattta actgctgagc
    33901 tgattttacg acgtgagcat cgattagagc taaaaagaga agggcaagaa aatgagtcaa
    33961 aaattgatag ggattgattt gggcggaacc acgattaaat ttggtatttt aacctcagag
    34021 ggtgacgttc aggaaaaatg ggcgattgag acaaatgttt tagaggacgg taaacatatc
    34081 gttccagata ttgtcgcctc actcaagcat cgccttgacc tttatggact gactaaggac
    34141 gattttatcg gtattggtat gggctcacct ggagctgtca atcgcacaga tcatactgtt
    34201 acaggggcct ttaacctcaa ctggagaggc acccaagagg tgggatctgt tattgaaagg
    34261 gagctaggaa ttccctttgc tattgataat gacgcaaatg ttgcggccct cggcgagcgc
    34321 tgggtcggtg caggtgacaa taatcctgat gtggtcttta tgaccttagg aacaggtgtt
    34381 ggtggtggta tcatcgctga tgggaacttg attcatggtg tggctggagc tggtggtgag
    34441 attgggcaca tgatagtaga gccgcttaag ggctttgctt gcacctgtgg ctcacagggc
    34501 tgcctggaga cagtggcctc tgctacaggt gttgttaagg ttgctcgtct tttagcagaa
    34561 gcctacgaag gagattcaag cattaaggca gcgattgata atggagaggc tgtctcaagc
    34621 aaggacattt ttgttgcagc ggaggctggt gatgcctttg ccaactctgt tgttgaaaag
    34681 gtcagttatt atctaggact ggcagcggct aatatctcaa atattttgaa ccctgattcg
    34741 gtcgttattg gcggtggtgt atctgctgcg ggtgagtttt tacgttcacg tgttgaaaag
    34801 tactttatga cctttacctt tccgcaggtt agacagtcca ctaaaatcaa aatagcagag
    34861 cttggtaatg atgctggtat tattggtgca gctagccttg caagacaatt tatcacagaa
    34921 taggagttaa tgatgtcacc acttacaatg attggctggg tattgcttgc gggagtgatt
    34981 gcctattacc tttggaatta tgtttcctat agaagaatgg caaagcaggt tgataatgat
    35041 acctttaagg agctgatgcg tcaggggcaa gtgattgacc tgcgcgatcc agcttccttt
    35101 agggcaaggc atatcctagg cgctagaaat tttcctgccc agcagtttac tacctctatt
    35161 aaggctttga gaaaggacaa gccaatcttg ctttatgaaa atgtaagacc tcaatatcgg
    35221 gtcaaagcag tcaaaacatt acgtaaggct ggctatacgg acctttatgt cctaaaagcg
    35281 ggactagatt attggaatgg taaggttaaa tagccttata gtcctttttg ctgagctaac
    35341 gtttgctgct atgtgtcgga acgttgcaag cagcagctta tctaagcttg tcatgctagt
    35401 ttcacagccc aaagtggctg gccgtataaa cgcagctgct tttagatgcc ggtaggagct
    35461 tttgtcagct tctttaggga ttgttttaag tgatgtagag aggccgttct gagagaaagc
    35521 cttgtagtta gaaaaagaga tgagaaagct aaggctcttg ctgctgttgt aagagttagc
    35581 tttctttttc ttttttgtgt ggcgcattta agggcttgaa aacatttaca attccctcag
    35641 atcggttttt taaaaaaatt tgtgttatac tgttttagtt aaaactattt atgctacaag
    35701 aggaaaaaat gacaaaattt agagaagata ttcgtaacgt tgctattatt gcccacgttg
    35761 accatgggaa aacaacgctc gttgatgaat tactaaagca atcccataca ctagatgagc
    35821 gcaaagagct tcaagaacgt gcgatggatt caaatgacct tgaaaaagag cgtggtatta
    35881 ccattcttgc taaaaatacc gcagtagctt ataacgatgt tcgtattaat atcatggata
    35941 ctcctgggca cgctgacttt ggaggcgagg ttgagcgtat catgaaaatg gttgatggtg
    36001 ttgtccttgt tgttgacgct tacgagggaa ccatgcctca aacacgcttt gtgctgaaga
    36061 aggccttaga acaaaattta accccaatcg ttgtggttaa taagattgat aagccatcag
    36121 ctcgtccagc tgaggttgtt gatgaggttc ttgagctttt cattgagctt ggtgcagacg
    36181 atgatcagct ggagttccct gttgtttacg cttcggcgat caatggcaca tcttcgttgt
    36241 cagatgatcc tgctgatcag gaaaaaacaa tggctccgat ttttgatacc attatcgatc
    36301 atattccagc acctgttgat aactcagctg agccccttca attccaggtg tcacttcttg
    36361 attacaatga ttttgtaggt cgtattggga tcggtcgtgt ctttcgtggg actgttaagg
    36421 ttggagatca ggtgacgctt tcaaagcttg atggcaccac taaaaatttc cgcgttacta
    36481 agctgtttgg cttcttcggg cttgagcgca aggagattca agaggccaag gctggtgact
    36541 tgattgcagt ttctggtatg gaggacattt tcgttggtga gacgattaca ccaacggatt
    36601 gtgtggaggc tttgcctgtt cttcgcattg atgagccgac acttcaaatg accttcttgg
    36661 ttaacaactc tccctttgct ggtcgtgaag gcaaatgggt aacctctcgt aaggttgagg
    36721 agcgtttgct tgtggagctt caaacagatg tgtcccttcg tgttgagcca acagaatcac
    36781 cagataaatg gattgtgtca ggtcgtggtg agctgcatct atctatttta attgagacca
    36841 tgcgtcgtga gggctatgag cttcaggtat cgcgtccaga ggttatcatt aaggaaattg
    36901 atggtgtcaa gtgtgagcct tttgaacgtg tacagattga cacaccagag gaatatcaag
    36961 gtgctattat ccaatccttg tcagaacgta agggggatat gcttgatatg cagatggttg
    37021 gtaatggtca aacgcgtctt atttttctca ttcctgcccg cggcttgatt ggttattcga
    37081 ctgaattttt atcaatgaca cgtggctatg gtatcatgaa tcataccttt gatcagtatc
    37141 tgccagtggt tgctggtgag attggtggac gccatcgtgg agcgctggtt tcgattgaaa
    37201 acggtaaggc aacaacctac tcaatcatgc gtattgaaga gcgcggaaca atctttgtta
    37261 acccaggaac tgaggtttat gagggcatga ttgttggtga aaattctcgt gacaatgacc
    37321 ttggggttaa tatcacaact gctaagcaga tgaccaacgt tcgttcagca acaaaggatc
    37381 agacagctgt tatcaaaaca ccacgtattc taacccttga ggaatctctt gaattcttga
    37441 atgatgacga atacatggag gtaacgccag aatcaatccg cttgcgcaag caaattttga
    37501 acaaagcagc gcgtgataaa gctaataaaa agaaaaaatc agcagaataa aggctggttg
    37561 gtctgagcat cacactccct tgccgcttta actagtaagc taggttggca gaggattgaa
    37621 aggagctttc tgtgttttat cttattattg cagccttgat tacctcttat tacctgttta
    37681 tggcaccaaa gagcgtccgt aacacactag gtatgattgg tttggttggt ttggttgccc
    37741 tattgattgt gctagctggc ttaagtttta tcaaaatcat gcaaacgccc aaggaaattt
    37801 tcgttggtct agccatgata gtattgggct actatgccct aagggacatt caaaaaatcc
    37861 ctaaaaaacc aaagagtaaa cattagcatc aagcattgag tcaaatctta atagggtttg
    37921 actttttctg tctttgtact ggccttatgc gctgctatct gtaaaatctt gaaaaagcag
    37981 ttaaataagg gtaaaatagt agtcaaatag acatagatag tgtggataaa aatgaagaca
    38041 ataacggaat tccaaaataa aaaggtattg attcttggcc tggccaaatc gggcgaagca
    38101 gcagctaggc ttttagcccg gttgggagct attgtgacag ttaatgatag caagcccttt
    38161 gaggaaaatc ccgcagcaca ggctcttctt gaggagggca taagggttat ttgtggtagc
    38221 caccccttgg agctgttaga tgaagacttt tattgtatgg ttaaaaaccc agggattcgc
    38281 tatgacaacc cgatggtggt acgcgcctta gataaggcta tttctattct aacagaggtt
    38341 gagctggctt atttggtatc tgaagcacct atcattggta ttacgggctc aaatggtaaa
    38401 accactacaa ccacaatgat tgctgatgtg ctaaatgctg ggaaccattc agctcttttg
    38461 gctgggaata tcggctttcc tgcttcagag gtggctcaag ctgctacagc aaaggatata
    38521 ctggtcatgg aattgtcttc ctttcagctg ctggggactg agcagtttca gccacatatt
    38581 gcagtcatta ctaacctagt gcctactcat cttgattatc atgggagttt tgaggactat
    38641 atagcggcca agtggcgcat tcaacatcga atgaccgata aggattacct tgtgttaaat
    38701 gctgatcaag agctggtaaa atcattggct caaaagacta aagcaagtcc tgtctttttt
    38761 tctaccaaag aaaaagttga tggtgcttat ttggcagatg ggtatcttta tttcaaagag
    38821 gagaggctga tgtcagcagc tgagcttggt gttcctggaa ggcataacat tgaaaatgct
    38881 cttgccacca ttgctgttgc aaagctaaga ggcatttcta atcaagtgat atcaaggact
    38941 ttgtctcact ttaggggggt gaagcaccgc cttcagttag ttggtacatt gaatcaagtg
    39001 accttctaca atgacagcaa gtcaaccaat atcttggctt gtcaaaaagc cttgtcgggc
    39061 tttgataata gcaaggttat cctgattgct ggtggcttgg atcgtggcaa tgaatttgat
    39121 gagctggtgc cagacctcgt tggtcttaaa aagatgattc ttttagggga atccgcagag
    39181 cgtatgaagc gagctgcaga caaggcagga gtgtcctatc ttgatgccaa agatgttgca
    39241 gctgccacta aaatagcctt tgagcaggca aaggctggtg atattatctt gctgagccca
    39301 gccaatgcta gctgggatat gtatccaagc tttgaaagcc gcggcgacga gtttttagca
    39361 gcctatgacg cgttaaaagg agaggctcaa tgaccaagaa aatcattttt accggtggtg
    39421 gaacagctgg tcatgtcact ttaaacctta tcctcatacc gaagtttatc aaagatggct
    39481 gggaggttca ctatattggt gatgacaaag gcattgagca tcaggagatc aaaaagtcag
    39541 gtcttgatgt cacctttcat gctattgcaa ctggaaaatt aaggcgttat ttctcttggc
    39601 aaaacctgct tgatatcttc aaggtaggct ttggtgtcat gcaatcactt tttatcatag
    39661 ctagactaag gcctaaggct ctcttttcaa agggaggctt tgtgtcggtt cctcctgtga
    39721 ttgctgcaag gcttttaggg gtgccggcct ttattcatga gtcggatctt tctatgggct
    39781 tggctaatag gattgcttat cggtttgcaa caacgatgta tacaaccttt gagcaagagc
    39841 agacactggc aaagctcaag catgttggag cggttaccaa ggtgacaggt cctgggagtc
    39901 gatcggtgac ttctaagcag cttgaagctg ttttggagta ttttgatcct aatttaaaaa
    39961 cacttttgtt tattggaggc tccgcagggg ctagggtgtt taaccgcttt atcactgacc
    40021 atcctgagct aaaggaagac tttaatatca tcaatatctc tggcgatcct agcctaaatg
    40081 agcttagttg gcatctttac cgcgtggatt atgtgactga tctgtatcaa ccgctcatgg
    40141 aaatggctga tctggtagtg actcgcggag gctctaacac actttttgaa ttattagcga
    40201 tgagaaagct ccagcttatt atcccacttg gcaaagaggc cagtcgaggt gatcagcttg
    40261 agaatgctca ttattttaca acaaggggct atgctgagca attattggag caggaattga
    40321 ccctgcctca ttttcaagag aaagtgagag aagtctttgc taagcaatcg gactatttat
    40381 ctgcaatgaa gagctctagc gagctccaat caccagaaag cttttaccag cttttaagtg
    40441 ccgacattag ctccgcgaca aaggaaaatt aaatggcaga taagacaaaa cattcagaag
    40501 aaaaagccgc tttgaccgaa tggcaaaagc gtaatattga atttctcaac aagaagcagc
    40561 agcaggctga gaaagacaaa aaactaaaag aaaaattatt aaatgagaaa atagcgcaag
    40621 ctcagggaga ggcagcttca aaggctgacc aagaagatac agatgaagct gaggagaaaa
    40681 ctgaggtaag ccaagcgggt actgatgagg gtgagccgct gccagaagca tcagagcagg
    40741 aagtcccctc cccaaaagac aagccattaa aagtccccaa agaaaaaagt ccaaagcagc
    40801 aggcacttca aaagggctgg cctgtattgc tggtgtcgtt tgtggttttg tgcctgtcga
    40861 tttttatgat cacaccctat agtaaggtca aggatttctc cgtcaagggc aataaaaaaa
    40921 caagcgttga ggacttagtt agagacagtg ggatcaagtc atctgattac tggattactc
    40981 tattagcctc tccgggttct tatgaaaatg cggttttaaa agccaatccc tgggtgaaaa
    41041 aggtggcttt gcgttacggc tttcccaatc atttccgctt tgatgtgaca gagtttgata
    41101 ttattgccta cgctcaggta gctgaagggt ttcaactgat cctagaaaat ggcaagcgag
    41161 ttgctgctgt caagcaggct gctttgccta aatccttttt gattttaaat cttgagcatg
    41221 aaaaagagat tcaagatgtc attaatcgct tgaccaaaat cccaagtgac ctagtcaagg
    41281 ctatcaaatc agtgtcatcg gccaattcac agacaactaa ggatttgctg cttcttgaaa
    41341 tgcacgatgg caaccttatc agggtacctc ggtcacagct tgagctaaag ctgccttatt
    41401 accaaaaaat caagaagaat cttgatactg ctagcattgt tgatatggag gttggtatct
    41461 atacgaccac tgctgaaatt gaaaacatgc ctgaggtgcc agcgtctgct caagcttctc
    41521 aggcagataa gcctgctgag gcttcaccag agcagggtga agagcaggcc acacaggagc
    41581 agcctagccc tgaaacacct gctaatcctg aggccacaaa tccctcagtc gcccagccta
    41641 ctgagcaggc aaatcaacag taatcgttta gggtaagaga agggggcaaa aaagcattta
    41701 aggctcttaa attaggccct tgttgaacgg caaaaaaaca ttaagtttat ataacaaaaa
    41761 acgtaaaatg gtaacatttt acgttttttt atgatataat attccctgaa taattctgct
    41821 ttttagcagt gtttttgaat agtaaaagtt tggaaagtaa gtgaggtcga gtgaatggct
    41881 agaaatggct tttttactgg tttggacatt ggaacaagct cgataaaggt tttggtagca
    41941 gagtttatct ctggcgagat gaatgttatt ggtgtgagca atgttccgag tactggcgta
    42001 aaagatggca taatcattga tatagaggca gcagccgctg ctattaaaac tgcagtagaa
    42061 caagctgaag aaaaagcagg aatgacaatt gaaagggtca atgttgggct gccagcaaac
    42121 ctccttcaaa ttgagccgac acaaggcatg attcctgttc ctagcgaatc aaaagaaatc
    42181 aaagatgaag acgttgatag cgttgttaag tcagcactaa ctaagagcat tactccagag
    42241 cgagaggtga tttccttagt ccctgaagag tttattgtag acggctttca gggcattcga
    42301 gatcctcgtg gcatgatggg gatcaggctt gaaatgcgcg gtctgattta cactggacca
    42361 agcacaatcc tgcataactt aagaaagaca gttgagcgtg ctgggattaa ggttgaaaac
    42421 atcatcattt ctcctttggc aatggctaag gcggtgttaa atgaaggtga acgtgaattt
    42481 ggtgctacgg tcattgacat gggtggagga caaaccaccg ttgcctcaat gcgagcacag
    42541 gaattgcagt acaccaatat ctatgcagag ggtggcgagt atatcacaaa ggatatctct
    42601 aaggttctta aaacgtcaat gtcaattgca gaggccttga agtacaattt tgggcaggct
    42661 gatatggcag aggcaagctt gactgacact gttaaggttg atgttgttgg cagtgatgag
    42721 ccagttgagg taacagagcg ttacttatca gagattatct cggctcgtgt tcgccatatt
    42781 ctagatcgtg ttaagcagga tttagaaaga ggacgcctgc ttgatttacc tggtggcatt
    42841 gtgctgatag gtggcggcgc cattatgccg ggcgtggttg aggttgctca agagattttt
    42901 ggaaccaatg ttaagcttca tattccaaat caggttggta ttcgtaaccc aatgtttgcc
    42961 aatgtcatta gcttggtcga gtacgttggt atgatgtcag aggtggacgt tttagcgcaa
    43021 aatgctgtat caggcgagga attgctaaga cgtaagccga tcgactttac tggccaagaa
    43081 gcttacttgc cagactacaa tgagactagg ggatttgaac cggctcctaa ttatgagcag
    43141 caagtgcccc aagcagacta cgagcctcaa gaacccgctg aaccaaagca aaagatttca
    43201 gagcgtgttc gtggcatttt tggaagtatg tttgattaaa agtaataaag tgaggaaata
    43261 aaatggcatt ttcatttgat acggcatcca ttcaaggtgc aatcattaag gtaatcggtg
    43321 ttggtggagg tggcggaaac gctattaacc gcatgattga tgagggggtt gcaggtgttg
    43381 agtttatcgc tgcaaacact gatattcagg cattaagctc atcaaaagca gaaacagttg
    43441 ttcagcttgg tcctaaatta actcgtggtc ttggtgctgg aggtcagcca gaggttggtc
    43501 gtaaggcagc agaggaaagc gaagaggttc tcacagaagc tttgactggc gctgatatgg
    43561 tctttatcac tgctggtatg ggtggaggct ctggaacagg agcagctcca gtgattgctc
    43621 gtatcgctaa gagcctagga gccttgactg tggcagttgt aacacgtcca tttggctttg
    43681 aaggcaacaa acgcagtaat tttgccattg aggggattca ggagctaaga gagcaggttg
    43741 ataccttatt gatcatctca aataataacc tgcttgaaat tgttgacaaa aagacaccat
    43801 tgcttgaagc gcttagcgaa gcagacaatg ttttgcgtca gggtgtacaa gggattactg
    43861 atctgattac aagccctggc ttgattaatc ttgactttgc cgatgttaag actgtgatgg
    43921 caaataaagg caatgcactt atggggatcg gtattggttc tggtgaggaa cgtattgtag
    43981 aggcagctcg taaggctatc tactcaccat tacttgaaac aacaattgac ggtgctgaag
    44041 atgttatcgt taacgtgaca ggtggacttg atatgaccct cacagaggct gaggaggcat
    44101 ctgaaattgt tggtcaggca gcaggtcaag gcgttaacat ctggctagga acatcgattg
    44161 atgactctat gagagacgaa attcgcgtaa cagttgttgc aacaggtgtt cgtcaggata
    44221 aggcggagca agcctcagga tttcgtcagc cacgcaccta cactcagtct aacgctcagc
    44281 aggctgctgg agcacaatat gcttcagagc aggtgagaca gactgcgcag ccaagctttg
    44341 atcgtcgttc atcaagcttt gattttgata tgggtgaaac acgtgagatg cctaagtctc
    44401 agcaagctat gccagctcat ggccacaatc ataatcaggg ctcagctttt ggaaattggg
    44461 acttacgtcg agacaatatt gctcgtccag cagaaggtga gcttgacaat caattgaaca
    44521 tgtcaacctt ctcatcaaat gatgacattg atgatgaatt agaaacacca ccatttttca
    44581 aaaatcgtta atgatggatt tacaaaaaaa taaggatatt gtttttgaaa atattcgctt
    44641 agccactcag gcagccaacc ggcctgaaaa cagtgtgtca gttatcgctg tcacaaaata
    44701 tgtggacaag gcagttgcag gtcagctgat tgatatgggg attgagcata tcgctgagaa
    44761 ccgtattgat aagtttctag ataaatatga agccttgaaa gataggcaag ttacttggca
    44821 ttttatcggt actttacagc gtcgaaaggt aaaggaagtg attaataagg ttgattattt
    44881 tcatgcctta gattcagtaa aactggcttt agaaattgaa aagagagctg accaccctgt
    44941 gaagtgtttt ctacaagtta atatttctga agaagaaagc aagcatggtt ttaagattgc
    45001 tgagcttgat gctgctattg aggaaatcag caagatggaa aagcttcatc ttgtcggtat
    45061 catgacaatg gcacctattg atgccagtca gcaagagctt agaagcattt tccaaaaagc
    45121 aaatcaatta agaaaaaact tgcagtcaaa aaagagaaag aatatgccgt ttacagaatt
    45181 gagtatgggc atgagtaacg attatccaat tgctattcaa gaaggctcaa cctttgttcg
    45241 tattggaaca tctttctttc actaaatgga gaataagatg gcaattaaag acgcatttaa
    45301 taagatgatt tcttattttg atactgatgg ggtcagtgaa gtagaagagg agctatcctc
    45361 taaaaagcaa gaagagcctg tgactaaatc acaacagacc agcagaccta atcagcagca
    45421 acaagcagct agagcgagtc agccccagca gcctaagcag gctagacctc agatgcaagc
    45481 tcagcaaaga ccacaatcac aatcaagagc tgcctatgct gagcgaccat atcaaggtca
    45541 aagtcaagca cgtgtttctc atgactacaa tgacagaagg gcgacgtcag ccccgtctgc
    45601 ttctagtcgt cgtgagcaat atcagcatgc tgctcatcaa gagcaaacaa ctattgcctt
    45661 gaagtatcct cgtaagtatg aggacgccca agaaattgtt gatcttttga ttgttaatga
    45721 gtgtgtgctg atcgattttc aatacatgct agatgctcag gcaaggcgtt gcctagattt
    45781 tattgacggt gctagtaagg tattgtatgg tactctgcaa agggttggtt cttccatgta
    45841 tctgttgacc ccatcaaatg tatctgttaa tattgaagag atgaatatcc caaataatgg
    45901 ccaagatatt ggttttgatt ttgatatgaa gagacgctag tgtgatgatt tttatactgt
    45961 tgatacttct aaagctaatt aaggtttatt cctatttgct gctagtctat gccttactgt
    46021 cttggtttcc tggagcctac gactcttggc ttggcaggct ggtcagcgat atagtagagc
    46081 ctatcttaaa accctttaga tcattgaacc tacagtttgc gggcttggac tttactattt
    46141 acctagtgat gattggtcta aatgttttaa gtgagatctt gataagagtg ttgatctcat
    46201 gactgttcaa acaatgcttt atcagcattt tcagcctgat gaacacccat ttattgaaag
    46261 aatgcttgac ttgatcgctc gtgttgaggc taattattta ttagaggtta ctgatttttt
    46321 aaatccgcga gaggtcacga ttttaaaagg cttagtcgca gcaaccaatc tgcagtgctt
    46381 tagctctact gattattatc ctagtgaata tggtcgtgtg attgttgctc ctgactatta
    46441 ttgtctagat aaggcagatt ttgacttggc tttgattgag gtgacctata atgctaagtt
    46501 taatcagctg acacatgcac agattttagg caccttaatt aatgaattgg gaatcaaaag
    46561 agccttactt ggcgatattt ttgttgagat aggtcatgct caggtcatga ttaatcgaca
    46621 gctgttaagc tattgtttag gaacgattgc taaaatagca aaagctaggg tcaagctcaa
    46681 agaaattgat cttgatcagc tgttaaatct gacagctaat cagcaggttc tgactgatat
    46741 aatggtatct agtctacgcg ttgatcgctt gattgctacc gtattaaagc aatctagaaa
    46801 tcaggcgata aggcttgttg aagcaggcaa ggtcaaggtt aactatcagc ttgtcactaa
    46861 agcctctcag cctgtagctg ttggtgattt aatcagcatt cgtggctacg gtaggtttag
    46921 catactaaca gacaatggct tcacaaaaaa tgggaaatat aagctaacac ttagcaaaat
    46981 gatgcgtaaa taaggagata taatggcact tacagcacta gaaattaaag ataaaacgtt
    47041 taagacaaag tttcgtggct acagtgaaga ggaagtaaat gaatttcttg agattgttgt
    47101 agacgattat gaggctttgg ttcgcaaaaa tcgtgataat gaagctaaga taagagagct
    47161 tgaagaaaag ctgtcttact ttgatgagat gaaggaatca ttgagtcaat ctgttatcct
    47221 agcccaggaa acagctgaaa aagtgaaatc ctcagcaaat gctgaagcaa ccaatttggt
    47281 cagcaaggca acctatgatg ctcagcattt acttgatgag tcaaaagcaa aggctaacca
    47341 actgttgcgc gacgcaacag atgaagcaaa gcgcgttgct attgagacag aggaattaaa
    47401 gcgccagaca cgcgttttcc atcagcgctt ggtttcagct attgagtcac agctaagctt
    47461 atccaattcg cctgagtggg acgaattgtt gcagccaaca gctgtctacc ttcaaaactc
    47521 tgatgcagcc tttaaagagg tggttaaaac tgtccttaat gaagatattc ctgaggctga
    47581 tgacagcaat tcctttgatg caacacgtca gtttacacca gaggagctag aggagctgca
    47641 gcgtcgtgtt gaagaaagca ataaggagct agaagcctat caggtgcagc gagaagagca
    47701 agctagcgag cctgaagtga acctaagcga gacacagacc tttaaattga atatttaatc
    47761 ataagaaaaa caggattgaa tgcccaaaat cacagcaagt aggagatgat gagagtccta
    47821 tattccctga gcatgacaat tatcattttc ttcaatcatc actgaatgac agtaagtgac
    47881 gagggaggct caccttacga gcaaagaggg aacagcaaaa gggattttac tgttctgaat
    47941 taaggtggta ccacgagctt tcgtcctttt tgagacgggg ctttttttgt aattctgata
    48001 agatattgac taaaaggagt ttgacaagat gaaattaaaa gaaacactta acttaggcaa
    48061 aacggccttt ccaatgcgtg ccggtctacc caacaaggag ccacaatggc aaaaggcttg
    48121 ggacgaggct gagatttaca aaaaacgtca agccttaaat gaaggcaagc ctgcctttca
    48181 cctgcacgat gggcctccct atgcaaatgg taatatccat gtcggacatg cgctgaataa
    48241 aatttcaaaa gacattattg tacgtgccaa atctatgtca ggctatcaag cgccttttgt
    48301 tccaggttgg gatactcatg gccttcctat tgagcaggtc ttggctaagc agggggttaa
    48361 gcgtaaagag atggatctgg ctgactatct tgacatgtgt cgtcagtacg cgttaagtca
    48421 ggttgataag caaagagacg actttaagcg tctcggtgta tctgctgatt gggacaatcc
    48481 ttatgttacc ttagatccaa gctttgaagc cgatcaaatt cgtgtctttg gtgcgatggc
    48541 tgataagggc tacatttatc gtggggcaaa gcctgtgtat tggtcatggt cctctgaatc
    48601 tgctcttgct gaggcagaaa tcgaatacca tgatattgat tctacatcgc tttactatgc
    48661 taatagggtt aaagatggta agggaatcct tgatactgac acctatgttg tggtttggac
    48721 gaccacacca tttacggtaa cagcttctcg tggtctaaca gttggacctg atatggatta
    48781 tgtggttgtt agacctgcag gttcagaccg taactatgtg gtggcagaag gactgctaga
    48841 cagtctggct gctaagtttg cttgggaatc atttgagatt ttggccaatc ataagggctc
    48901 tgacttggaa tacattgtaa ccgagcaccc ttgggacagt gaggttgatg agctagtcat
    48961 tcttggcgat catgtgacgc tagattcagg tacaggtatc gttcatacag cacctggctt
    49021 tggtgaagat gactacaacg ttggtatgac atatggactt gaggttgcag ttacagttga
    49081 tgagcgtggt ttgatgatgg aaaatgcagg tcctgatttt catggtcaat tttatggcaa
    49141 ggtaactccg attgttattg aaaagcttgg agacctattg cttgctcaag aagtgatcaa
    49201 ccactcctat ccatttgatt ggcgcacgaa aaaaccaatt atttggcggg ctgttcctca
    49261 gtggtttgct tctgtgtctg acttccgtca agagattcta gatgagattg acaaaacaac
    49321 attccacccg acatggggaa agacacgact ctacaatatg attcgtgatc gtggcgattg
    49381 ggtgatctct cgtcagcgtg cttggggtgt tccactgcct attttctatg cagaggacgg
    49441 cacagccatt atgactaagg aggtaactga tcacgtcgca gatctgttcc aagagcatgg
    49501 gtccattatt tggtggcaaa aagaggctaa ggagctttta cctgaaggct tcacacaccc
    49561 aggctctcca aatggggtat ttaccaaaga gacagatatc atggacgtct ggtttgattc
    49621 agggtcttct tggaatggtg tgatgaatgc tcgtgatcat cttgcttatc cagctgacct
    49681 ctaccttgag ggctccgatc aatatcgtgg ttggttcaac tcatcactga ttacctcagt
    49741 tgcggttaat ggtcatgcac cgtataaggc tatcctatca cagggctttg tccttgatgg
    49801 taagggtgaa aaaatgtcta aatctaaagg aaatatcatt tcacctaatg atgttgcaaa
    49861 gcaatatggt gctgatattc tccgtctctg ggtagcttct gttgatacag ataatgatgt
    49921 gcgtgtgtca atggatatcc taggacaggt ctctgaaacc tatcgtaaaa tccgtaacac
    49981 gcttcgcttc ttgcttgcta atacatcaga cttcaatcca catacagata aggtggctta
    50041 tgctgagctt gctgctgttg ataagtacat gaccatcaag tttaacaagc tagtaggagc
    50101 tatcaatact gcctatgagc gttatgactt catgacgatt tacaaggctg tggttaactt
    50161 tgtgacggtt gacttatctg ctttctacct tgattttgcc aaagatgtgg tctacattga
    50221 ggctgctaac agcctggcac gtcgtcgtat gcagactgtc ttttatgata ttttggttaa
    50281 tatcactaag ctattgactc cgatccttcc acatacggca gaggaaatct ggtcatattt
    50341 agagcatgag ccagaagact ttgtacagct atcagagctg ccacaggctc agacttttga
    50401 taatcaagat actatcctag aggaatggga agcctttatg acgcttcggg cacaggcgca
    50461 aaaggctttg gaggaagcac gtcatgacaa gattattggt aagtccttag aagctcatct
    50521 gacaatttat gcaagtccag aggttaagac actgttgaca gctctagata gcgatattgc
    50581 actgctattg attgtctctc agctaaccat tagtgaggag ccagctcctg agaatgctgt
    50641 cagctttgat gatgttgcct ttacggtagc tcgtgcgcaa ggagaggttt gtgagcgttc
    50701 acgtcgtatc gatccaacga ccagaatgcg gtcttataat gcctttgttt gtgaccacag
    50761 tgcgaaaatt atcgaagaaa acttcccaga agcagtagca gaaggctttg actcagctgc
    50821 taattaagca actaacagct ctgttcccga gttaaataag cattggcgtg cttttgccaa
    50881 tccagcagca aggtgctagt cggtctgggc gtacctgcct tactagggac tctttgtgtg
    50941 ggagctgata agtgacctgc cttgagcttg gcaggtctag gcttctttat aggttcacga
    51001 tttacgattg actgggctta gagaagggct agtcctgcta ggcggcattg gatatgaact
    51061 gagtagtcat catagctata aaaaaacaag cgcagactca cgtcagctta atcgtgagcg
    51121 gcgcttgttt tttcttggtt ggggggtgaa ggcgaggagc tattaaagct aatattaagc
    51181 gatcaaaaaa gcctagacca ctagtcatgt tgtctaagct tcagctgtta gagaggagct
    51241 ttctgagtgg aaggtagcct atgctgatag gtgctgcctt agccttttag cagtagtatt
    51301 aaggctagac agacgtctgg aaggaaattt caatcaaatt attggtgtgc agggtttttg
    51361 agtgacctgg aatcacaata gattggtcaa tcttacgctt taagaaaaat tcgcgaatca
    51421 cttcaagctc gtcctctttg atggcacgat atttatttga aatgagtagc tcataatgct
    51481 tgggtgcttg cgtaaagatg acgtcagtgt taccagctga gtaaacttca acgaggtgag
    51541 catctgtatt ttgcagctga tttctgacaa gctcggggtg actgctggtg gtattaataa
    51601 gtctcataaa tcttctcctg actattttta cttttattat agcactattt ttaaattgat
    51661 tacggatttt aatggtgctt tttctgccat tcttcgacgc cccatctgtg gctatcacgc
    51721 tttaagactg ttatggcgtc cgcaatagga agaaaccaag ccagatggtt aaagtcttcc
    51781 aagggctttg agatagcttg gaatgatgtc acctcgtaca ggtaggcagg attatagtag
    51841 taggtatcgc ggtgacgaga atagaagtat tcgtctgctt gaccataata ataaccaata
    51901 tcagcagcaa atcccagctc ctcaactagc tcacgctcca gtgcctgtag ctggctttca
    51961 ccagcctcta tttctcctcc tggcaaaaac caagcaccat ttggagcctg cactaggata
    52021 atctctgttt tagccgagtt aggaatcact gcatagacac cgtaacgtgc ggtgtaatgc
    52081 tggtcatcta tcttatcacc aaatattgga acggtcatat cgcttctcct ttgttttatt
    52141 atactaaatt tttggtcatt attctcataa aactgtagat ttatcaaaaa tgtttcataa
    52201 aaaaatgctc gtcaaaaaga gagaaaatgc tgtctgcttt tctctctgct tttctctctg
    52261 ctttttggta tgccctgtta gtccgcctgc ttcgcctgag atttgactac aggcttgatt
    52321 ataatgtgtc cattagaggt caagacagct cgcatgtctt tttctgctgg gtgctcaagg
    52381 tagaagtcag taatggcgtc ctcaatgtag tcctgaatgg tgcggcgcaa tggtcgtgct
    52441 cccatcttag gatcatagcc tagctcaacg agcttttctt tgaccttttg ggtgacatca
    52501 aggcgaatgt tattgtgagc aaggcggtgg ttaacatcat cgagcattaa atgaacgata
    52561 tgtaaaagat tgtccttgct tagtggctga aactcaataa tgccatcaaa gcgattcatg
    52621 aactcggggc taaagaaatg actgagctct cctaaaacag agtttgtccg cccttctcta
    52681 gcagcgccaa agcctactga ggcctctgtt ttgccagtgc cagcatttga tgtcatgatg
    52741 ataatagtgt ccttaaagct aacggtacgt ccttgtccgt cggttaatcg tccgtcatct
    52801 aggacctgta aaaacatgtg catgacatca gggtgagcct tttcgatctc atctaacaaa
    52861 atgagcgagt aagggttgcg gcgcacctgc tctgttaact gacctgcctc ctcatagccg
    52921 acgtagccgg gaggggcacc gacaagctta gccacagcgt gcttttccat gtattcagac
    52981 atgtcaaagc gaatcatgtt atcagcagag ccaaaaagct caatggctaa ttgcttggaa
    53041 agctctgttt taccgacacc agttgggcca acaaagagga aggagccgat aggacgattt
    53101 ggggctccca gtccaacacg attacgacgg atagcttttg caattttatc aacagcatcg
    53161 tcttgaccga taacatgctt tttgagatcg gcggccagat tgactagctg tgattgttcc
    53221 ttttccttta aatcaccaac tggaatattg gttttttgct caacgattgc ttcgatggtc
    53281 ttgtcagtga tgattggaat atcctgctca tctagctttt gagcctgcat ttctttatat
    53341 ttggcgattt gatcgcggaa ataggctgct cgctcataat cctcatcacg tgtggcttgt
    53401 gtcttgaggt tttcagcctc aatcaaacgc ttatcaatgt ctttggggtc aacaaagtta
    53461 agggttaggt tcatctttga gccggcttca tctagcaggt caatggcctt atcaggcaag
    53521 aagcggtctt gaatatagcg gttggagagg ttagcagctg cttcaatagc cgactggcta
    53581 tatttgacat ggtgatagtc ctcatatttg ggttggattc cttttaggat agtgattgtt
    53641 tcttcaaccg aaggctcgtc caccttaacc ggctgcatgc gtcgctcaag ggctgcgtcc
    53701 ttttcgatga tgcgatattc attgagagtg gtcgctccca ctaattgaag ctcaccacga
    53761 gcaagtgctg gctttaaaat atttcctgcg tccatgctgc cgtcaccaac tgcaccagct
    53821 cccacaattt catggatttc atcaataaat agaatcacgt catggcgctt gcggatttcc
    53881 tccatgagct tttgcatgcg ctcttcaaat tggccacgaa tacctgtccc ctgaacgagg
    53941 ctaaccacat caaggcgaat cacctgctta ctctgtagct tttgtggcac atcgccatca
    54001 acgatttttt gagcaaggcc ttcaacgaca gcagtcttac caacacctgg ttctccgatt
    54061 aggacagggt tatttttggt acgacggttg agaatctcga tcacgcggat aatctcatcg
    54121 tcacgtccga tgacaggatc aatatcacca cgcttagcca tttcagtgat attaatgccg
    54181 aattcctcaa gcaaaccttt gttagcctct tgtgctggct gtgtgtgatt gggacggtag
    54241 ccattgtgac ctccgccatt atggccgcct gattgggtag gtggtgtatt gggcaattga
    54301 ccgaaggctc taaaattgtt caggtcacca aaaaagtcat caaagaaagg gttttgagaa
    54361 ggctgctgcg ccttttggtt gccattatag cctcctaaga taggattttt agggtctgtt
    54421 ttcatgattt ggtagcaatt ttgacagagg tcaatctgcc tttgctttcc gttaatgctt
    54481 gtataaagat gaatggttga ttcgtttaaa ttacagtttt gacaaagcat atcatacctc
    54541 caaggggtta tctaaaaagt caaggtcatt tagtcaaaaa tggtcaaact ttatagtcat
    54601 attatagcac cttaggcttg gaaatcaagt aaaaagcttc attattagca ctttcaggta
    54661 tagagtgata atctctataa atcttgctgc tcattggttc aaaaaagtcg tcaaagggga
    54721 taaaataaag agaaaatggc tacttttctt gtttgttttc gatgatttat gttaaaatat
    54781 atagggacaa taaacgaata ggagaaacga aatggaatca catttagtga gaatcatcaa
    54841 ccgtctggag ctgatggtaa cagatggcgg taatttaaag agaaactttg agcgagatgg
    54901 tgttgttgtt gcagaggttg catttgtcaa cgatcctgaa aatggtccag tctttatttt
    54961 acgtgatatt gaagcgcgtg agtcatattc atttgatagc atcgatttga ttgcgatgga
    55021 aatttacgat ttgttatatt aagctattga tgatgacatg ggcttgctgg gaggcaggtc
    55081 agacagagga caagctggtg atttactggt ttgtttttat tatcccttaa agcctcaaga
    55141 cagctccagg aaaggccttt ctcctatggt ctttctagcc ggtagggctt gatagtgatt
    55201 aatagtgatc tgctctagca cggtcttgag cttttactgt cagaggcttg tgaccttagc
    55261 cactcgcagt aaagggtact ggcccagtaa gcaaggtagg ctaagtatca atgtgaagtt
    55321 ctaaccttga tcttagtgaa atatttttga ggtgaattaa gatgttaaaa gtccttagaa
    55381 tgctcatttc taagggtttt gttgtgtcta gctgttggtg tttgaaagag cggtggtatg
    55441 ataaagagag gtcagaaaag acctctctga tgtttgtgat tagctgttag ctattgccat
    55501 aggggaaaga cacaatagct agcttagctt ttctttttct ttaggtttag gacgcctgcg
    55561 ctagtgatga cgctaagggc tgcaagggtg aagaatgggt gatttgtctc ccctgtagct
    55621 ggtagcgtgc tcttttgagc tgctggtgct gacttaggcg ctggtgcttt aggctgagct
    55681 gatttttctg gagcctttgg tgcaggtgtc ttttcaggtg cttttggagc tgatggtttt
    55741 gtatcttttc cttgatcacc ctttggtttt tgctcgcctt tttcgccgcg ttgtccttgc
    55801 tcgccttttt c
//
LOCUS       DARYUW010000005        52117 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYUW010000005 DARYUW010000000
VERSION     DARYUW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52117
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..701
                     /locus_tag="TVW11_000258"
     CDS             <1..701
                     /locus_tag="TVW11_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1364401.1"
                     /translation="GRKRILLPEEEWEIIHNTHEAIVSREVFDKVRIIKKKRIFGGYA
                     KNREESVFSDKIFCKECGRHMGFRCDSRQKKNPNKVYKYRNYYCYFCKASRTPNNVKE
                     RDIIELIRPKLDEFKLQNTEKDKKTMDYEKIKEEYLREISALNSNLQIIYENYKKNSI
                     SKEEYLRKKILVQDRKKLLENKIKELENVEDDSKKELDINNLDEDNLLKIYVDNIIDK
                     IIASRTGEIEIIEK"
     gene            742..1356
                     /locus_tag="TVW11_000259"
                     /pseudo
     CDS             742..1356
                     /locus_tag="TVW11_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1886..2764
                     /gene="mvk"
                     /locus_tag="TVW11_000260"
     CDS             1886..2764
                     /gene="mvk"
                     /locus_tag="TVW11_000260"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1364402.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2746..3690
                     /gene="mvaD"
                     /locus_tag="TVW11_000261"
     CDS             2746..3690
                     /gene="mvaD"
                     /locus_tag="TVW11_000261"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1364403.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3683..4681
                     /locus_tag="TVW11_000262"
     CDS             3683..4681
                     /locus_tag="TVW11_000262"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1364404.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4684..5676
                     /locus_tag="TVW11_000263"
     CDS             4684..5676
                     /locus_tag="TVW11_000263"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1364405.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5961..7244)
                     /locus_tag="TVW11_000264"
     CDS             complement(5961..7244)
                     /locus_tag="TVW11_000264"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1364406.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(7231..8406)
                     /locus_tag="TVW11_000265"
     CDS             complement(7231..8406)
                     /locus_tag="TVW11_000265"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1364407.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            8591..9430
                     /locus_tag="TVW11_000266"
     CDS             8591..9430
                     /locus_tag="TVW11_000266"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1364408.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            9511..10008
                     /locus_tag="TVW11_000267"
     CDS             9511..10008
                     /locus_tag="TVW11_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1364409.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            10028..10198
                     /locus_tag="TVW11_000268"
     CDS             10028..10198
                     /locus_tag="TVW11_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364410.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            10234..11463
                     /gene="clpX"
                     /locus_tag="TVW11_000269"
     CDS             10234..11463
                     /gene="clpX"
                     /locus_tag="TVW11_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1364411.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            11473..12072
                     /locus_tag="TVW11_000270"
     CDS             11473..12072
                     /locus_tag="TVW11_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1364412.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            12436..15438
                     /locus_tag="TVW11_000271"
     CDS             12436..15438
                     /locus_tag="TVW11_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1364413.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(15628..17721)
                     /locus_tag="TVW11_000272"
     CDS             complement(15628..17721)
                     /locus_tag="TVW11_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1364414.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            18092..18511
                     /gene="ndk"
                     /locus_tag="TVW11_000273"
     CDS             18092..18511
                     /gene="ndk"
                     /locus_tag="TVW11_000273"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1364415.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            19012..19818
                     /locus_tag="TVW11_000274"
     CDS             19012..19818
                     /locus_tag="TVW11_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1364416.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(20110..21075)
                     /locus_tag="TVW11_000275"
     CDS             complement(20110..21075)
                     /locus_tag="TVW11_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1364417.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            21247..22530
                     /locus_tag="TVW11_000276"
     CDS             21247..22530
                     /locus_tag="TVW11_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1364418.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            22532..23392
                     /locus_tag="TVW11_000277"
     CDS             22532..23392
                     /locus_tag="TVW11_000277"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1364419.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            23557..24816
                     /locus_tag="TVW11_000278"
     CDS             23557..24816
                     /locus_tag="TVW11_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1364420.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24816..25439
                     /gene="folE"
                     /locus_tag="TVW11_000279"
     CDS             24816..25439
                     /gene="folE"
                     /locus_tag="TVW11_000279"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1364421.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            25447..26247
                     /gene="folP"
                     /locus_tag="TVW11_000280"
     CDS             25447..26247
                     /gene="folP"
                     /locus_tag="TVW11_000280"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1364422.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            26254..26613
                     /gene="folB"
                     /locus_tag="TVW11_000281"
     CDS             26254..26613
                     /gene="folB"
                     /locus_tag="TVW11_000281"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1364423.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            26610..27116
                     /gene="folK"
                     /locus_tag="TVW11_000282"
     CDS             26610..27116
                     /gene="folK"
                     /locus_tag="TVW11_000282"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1364424.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            27212..28099
                     /gene="murB"
                     /locus_tag="TVW11_000283"
     CDS             27212..28099
                     /gene="murB"
                     /locus_tag="TVW11_000283"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1364425.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            28145..29299
                     /locus_tag="TVW11_000284"
     CDS             28145..29299
                     /locus_tag="TVW11_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364426.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            29283..30077
                     /locus_tag="TVW11_000285"
     CDS             29283..30077
                     /locus_tag="TVW11_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364427.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            30074..30850
                     /locus_tag="TVW11_000286"
     CDS             30074..30850
                     /locus_tag="TVW11_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364428.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30843..31916
                     /locus_tag="TVW11_000287"
     CDS             30843..31916
                     /locus_tag="TVW11_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1364429.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            32074..33606
                     /locus_tag="TVW11_000288"
     CDS             32074..33606
                     /locus_tag="TVW11_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1364430.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33812..34426
                     /locus_tag="TVW11_000289"
     CDS             33812..34426
                     /locus_tag="TVW11_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1364431.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34774..35901
                     /locus_tag="TVW11_000290"
     CDS             34774..35901
                     /locus_tag="TVW11_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1364432.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            36053..36730
                     /gene="radC"
                     /locus_tag="TVW11_000291"
     CDS             36053..36730
                     /gene="radC"
                     /locus_tag="TVW11_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1364433.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36732..37427)
                     /locus_tag="TVW11_000292"
     CDS             complement(36732..37427)
                     /locus_tag="TVW11_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1364434.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(37439..38083)
                     /locus_tag="TVW11_000293"
     CDS             complement(37439..38083)
                     /locus_tag="TVW11_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1364435.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(38369..38716)
                     /locus_tag="TVW11_000294"
     CDS             complement(38369..38716)
                     /locus_tag="TVW11_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1364436.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38706..39833)
                     /locus_tag="TVW11_000295"
     CDS             complement(38706..39833)
                     /locus_tag="TVW11_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1364437.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39836..40810)
                     /locus_tag="TVW11_000296"
     CDS             complement(39836..40810)
                     /locus_tag="TVW11_000296"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1364438.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40945..41517)
                     /locus_tag="TVW11_000297"
     CDS             complement(40945..41517)
                     /locus_tag="TVW11_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1364439.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            41612..42283
                     /locus_tag="TVW11_000298"
     CDS             41612..42283
                     /locus_tag="TVW11_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1364440.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            42258..43094
                     /locus_tag="TVW11_000299"
     CDS             42258..43094
                     /locus_tag="TVW11_000299"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1364441.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            43091..43993
                     /locus_tag="TVW11_000300"
     CDS             43091..43993
                     /locus_tag="TVW11_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1364442.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43997..44998
                     /gene="pta"
                     /locus_tag="TVW11_000301"
     CDS             43997..44998
                     /gene="pta"
                     /locus_tag="TVW11_000301"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1364443.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            45098..45856
                     /locus_tag="TVW11_000302"
     CDS             45098..45856
                     /locus_tag="TVW11_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1364444.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45961..46647)
                     /locus_tag="TVW11_000303"
     CDS             complement(45961..46647)
                     /locus_tag="TVW11_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1364445.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46902..47630
                     /locus_tag="TVW11_000304"
                     /pseudo
     CDS             46902..47630
                     /locus_tag="TVW11_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            47623..49155
                     /locus_tag="TVW11_000305"
                     /pseudo
     CDS             47623..49155
                     /locus_tag="TVW11_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            49513..50496
                     /gene="guaC"
                     /locus_tag="TVW11_000306"
     CDS             49513..50496
                     /gene="guaC"
                     /locus_tag="TVW11_000306"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1364446.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50682..51263
                     /locus_tag="TVW11_000307"
     CDS             50682..51263
                     /locus_tag="TVW11_000307"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1364447.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(51551..>52117)
                     /locus_tag="TVW11_000308"
     CDS             complement(51551..>52117)
                     /locus_tag="TVW11_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1364448.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14833 a         9805 c        11924 g        15555 t
ORIGIN      
        1 gaggaagaaa aagaatcttg cttcctgaag aagaatggga aataattcat aatactcatg
       61 aagcgattgt ttctagagaa gtttttgata aggtaaggat aataaagaaa aaaagaattt
      121 tcgggggata cgcaaaaaac agagaagaat ctgttttttc tgacaagatt ttttgtaaag
      181 aatgcggtag acatatggga tttagatgtg atagtaggca aaagaaaaat ccaaataaag
      241 tgtataaata tagaaattac tattgttatt tctgtaaagc tagtagaact cccaacaatg
      301 tcaaagaaag agacattata gagttgataa gaccaaaatt agatgaattt aagttacaaa
      361 atacagaaaa agataaaaaa acgatggatt atgaaaagat aaaggaagag tatttaagag
      421 aaatatctgc attaaatagt aacttgcaaa taatctatga gaattacaag aaaaatagta
      481 tttcaaaaga agaatattta cgaaaaaaaa ttcttgttca agacagaaag aagttactgg
      541 aaaacaagat aaaagaatta gaaaatgtag aagatgattc caagaaagaa ctggatatta
      601 ataacttaga tgaagataat ttgttgaaaa tatatgtaga taatataatt gataaaataa
      661 ttgcatcaag aactggagaa atagagatta tagagaaata gataattcag gaaattctat
      721 atcaattgct tgacattgta gggaaagtcc tctatcatga atttgctgta tcgcttttat
      781 gatgtacaat caggcctcat tacagttgat gggcaaaata ttcaggagta ttctagagaa
      841 agcctgcgtt cacagatggg tattgtcttg caggatcctt atttgtttac aggaacgatt
      901 gcttctaata tcacgatggg aaatccagct tattcggatc aggatatttt agatgctttg
      961 gaaaaggtcg gagcctcttc gatgattgct cgtctggaaa agggcattca tgagcctgtc
     1021 tatgaaaaag gctcctctta ttcaagtggc gagcggcagc taattgcttt tgctaggaca
     1081 ttgattgccg accctaaaat tttgatctta gatgaagcga cctcgcacat tgatactgag
     1141 acagaggaca tcattcaaca ggctatggag gtcttaaaga aaggccgaac aacctttatc
     1201 attgcccatc gcttgtctac cattcaatct gctaatcaaa ttttagtatt ggataagggg
     1261 aggatcgtcg aaagaggaac acatcaggaa ttgctagatc agcaaggcat ttatgctgaa
     1321 atgtccaagc tacaagaaaa ggtggctgta cagtaatgct ttttagtgat agctatcaaa
     1381 aaattccttt tctaggccgt gttaagcagc agtagtctgt gaagtaggag ctatatttag
     1441 gttttgtgcc taagccttta aggtttttaa gaggctggat tagggcttaa catcaataaa
     1501 atcatatgtc actttatcac agcatgttgt ggtgaagtgt tttttgtgtc gtcctgctaa
     1561 agggaagatc ctcacagtca gggcttggct ggctccttta tcagagtcag atcattcata
     1621 cgtacttcct gtcaggcttg gctaagttga attgtatgtt gagatcagca tgtcagcaat
     1681 ttatgctttg tgtctgactt ttagcagctt gtacatgaaa taggactaaa ggacacttga
     1741 attgatgaag aatcagctta aaaaccattt gtcctagata ggataagaac tgtctaaaag
     1801 ggggatagat catcgcaatt tttaacaatt tagtgtaaaa tagtaaggtg aatgttttga
     1861 tgaaataaac gaaaagattt aggatatgaa taagacaatt ggatatggca aggcacacag
     1921 caaaatcatt ttaatgggtg agcattctgt ggtctatggc taccctgcgt tggccttgcc
     1981 cttaaaagat attgaagtga cctgccggat tttccctgct gcaaagccct tagcctttga
     2041 tttttatgat cccttatcaa cggcagttta tgcagccttg gagcatttgg ggtgcttggc
     2101 agagcccatt cattatgata ttatgtctca ggtaccacaa aagcggggca tgggctcctc
     2161 agcagctgtt tcgattgcag ctgttcgagc tgttttttct tattttgggc agcccttgtc
     2221 agatgagctg ttggaaatct tggtgaataa ggcagaaatc attgctcaca ccaatcccag
     2281 tggcctagat gctaagacct gcctcagtga taaggccatc aaatttatta gaaatgttgg
     2341 ttttgatacc attgatattc agttaaatgc ttatttggtc attgctgata cagggattca
     2401 ggggcatacg cgtgaggctg tcaataaggt ggctcaattt gaggaggaaa atcttcctca
     2461 tttagccaag cttggctgtt tcacagaggc tgttgagcaa gcaattaaga caaacgattg
     2521 cctagctatt ggacgattca tgacgcaggc acatgaatca ctaaaggcta ttggtgtcag
     2581 tgtggcaaag gctgatcagc tggttgcagc agctcttgag gctggcgctt taggagctaa
     2641 aatgactggt ggtggcttag gaggatgtat gattgcatta gctgaaagga taacagacgc
     2701 tcagcaaatc agtaagaaac taaaagaaga gggagctgta aatacgtgga ttcaaatact
     2761 gtaacggtaa cttcctacgc taatattgct attgtcaaat actgggggaa aaaagatgag
     2821 gctaagatga tcccatcaac ctctagtatt tctttgacct tggaaggcat gtacacgaca
     2881 acaagtcttt cttttttgcc tgcctcagca aagggagatc agttttatat caatggtgtt
     2941 ctgcaggacg ccaaggagca tgctaagatt actgcgattt tggatcagtt ccgtcagaag
     3001 gaccagactt ttgtcaaggt tgaagccagc aacagcatgc caactgcggc aggcttatcc
     3061 tcaagctcta gtggcttatc tgctctggta aaggcctgca atcagctttt tcaagctaag
     3121 ctaagtcaag aagagcttgc ccaaaaggct aagtttgcct ctggctctgc ttcgcgttct
     3181 ttttttggcc ctgttgctgc ctgggataag gatacaggct ctatttataa ggtcaaaaca
     3241 gatttaaagc tggccatgat tatgctggtc ttgaacgatg ctagaaagcc catttcgagt
     3301 cgagagggga tgaagcgctg cagcacaacc tcaacaagct ttgaccagtg gctggcccag
     3361 tcagaaagtg attatcaggc catgttgcgt gcccttagtg acaatgattt tgaaacggtt
     3421 ggttggctga cagaagcaaa tgctctagcc atgcacgcaa cgaccaaaac agccagtcct
     3481 tccttctctt acctaacaga ggcctcctat caggccatgc taagggtcaa agagcttcgt
     3541 caagagggct attcttgcta ttttacgatg gacgctggtc caaatgtcaa ggtgctttgt
     3601 ttagaagagg acttagagcg gctgtcgcac ctttttgaaa gggagtatcg tatcatcgcc
     3661 tcaaaaacaa aggaattacc agatgtctaa atatcatgtt caagcaggag gaaagctgta
     3721 tctgacaggc gaatatgcga ttctaaggcc ggggcaaacg gcgttgattt gctatattcc
     3781 cataatgctg acagctgtca ttgaagcagc agaggctgtt agtatcagct cagatatgtt
     3841 tgaccatgct gctgatttgt caccggataa ggattatagg ctgattcaag cctctattga
     3901 agcctttagt ttatatatag ataaggatat taaggagctg ccagcctttt ctttgtctat
     3961 tactggtaag cttgagcgtg acggtaaaaa gtttgggatt ggctctagcg gtagtgttgt
     4021 tgtactaacg ctaagagctt tggcagcctt ttatcaggtt cagctgctac cagagcagct
     4081 ctttaagctg gctgcttata ccctgcttaa atcaggagat aatggctcca tgggggacat
     4141 tgcctgcatt gcctatgaga gcttggttgc ttatacatcc tttgataggc gtaaggttgg
     4201 tcaatggttg atcgagatga ccctaaaaga gctaatggca gcacattggg ggtatacgat
     4261 tgagactatt gagcctgctc tgccctgttg gtttcttgtt ggctggaccc aagtcccttc
     4321 tatctcaaga gagatgattc agctggttaa caagagcatt agctgtcagt ttttagagca
     4381 aagccagctg gtcacacagg aagtgatgac tgccctgcag cttggtcaaa gaaaaaggct
     4441 caaagctagc attgaaaaag cgggtcagtt gctgcaaggg ttggcttcag ttatttatca
     4501 ccctaagctt acgcagcttg tccaggcttg tcaagggctt gatgctgctg ccaaatcatc
     4561 aggctcagga ggtggggatt gtggtattgc actcgttttt gaggctaagg acattgagcc
     4621 tatccttgcc agatggcagc aagcagggat tgtattacta tatcaggagg aatggggata
     4681 aacatgacta atcgtaagga tgaccatatc acacatgctt tgagctatca ttctccttac
     4741 aatgcatttg acgacatgga gctcattcac tgttccttgc cgagctatga tttagctgat
     4801 attgatctct caacccattt tgctggctgt gattttgagt ttccttttta tatcaatgcg
     4861 atgacaggtg gtagcaagaa aggccaagca gtcaatgaaa agctggccaa agtggctgcg
     4921 gctacaggta ttttaatggt gacaggctct tacagtgcag ccttgaaaaa tcctgaggac
     4981 acttcctttc aattgcgagg tgtagcacca gatttacagt tggccaccaa cattggtctt
     5041 gataaggctg ttgacctagg gattagagct gtcgaggaaa tgaagccctt gtttttacag
     5101 gtacatgtga atgccatgca ggagctgtta atgccagagg gagagcgcag ctttaagcat
     5161 tggaaggatc atttagcggc ctatgccaag cagcttccag tccctttgat tttaaaagag
     5221 gttggctttg gtatggatat taagaccatc actatagcac gtgatatggg agtaaaaacc
     5281 tttgatattt caggaagagg aggaacctcc tttgcctaca tcgaaaatca aagaggaagt
     5341 aatcgctctt acctagacga ttggggacag acaacagtgc aatgtctatt aaacgccaaa
     5401 ggtctggttg atgaagtgga gatcttagcc tcaggtggtg tcagacaccc cttagatatg
     5461 gttaaatgct tggtgctggg ggcacgtgct gtgggcctat cgcgagtggt attggagtta
     5521 gttgagacct atccagttga gcagatcatc gctacgatca atagctggaa gaaggagctt
     5581 aagctcatca tgtgtgcttt agattgtcga accttgagcg atttgcgtca ggtggattat
     5641 ttattatatg gtaggcttta tcaggcaaac cgctaaagac tttttagccc tgagctaact
     5701 ttccttagaa aatcatcaca ggagttaaga agctgcctgc ttggtgctgc aagctaattc
     5761 agctgattat ggctcgtaag atttttagat gtctgaatga aatgatagga cagatgacat
     5821 agtatagcgc taatttctag tgaaaatcag tccttggtca ggttactgag actgaggtta
     5881 agtttatgtt tacactaaca cttaaaggat atgaaaacac ttggtagctg ccactgaagc
     5941 tgttaccaag tgtttttagt ctatgattgg cttaatcgta tggctgttaa gagctgtcct
     6001 gccttttcta ggttcattgg cttatccttt agtagagcct taactagttg aggcacctcc
     6061 tgctcactag cacctgctaa tagagctaga gacttggcct gcagcttcat gtgaccagcc
     6121 tggataccag ttgaggtcaa agcctttaga gccgcaaaat tttgcgccag cccaactgca
     6181 gtggtgattt gggcgagaac cttagcattt ggttgctcta aaaggctatg agcaacactg
     6241 acggttgggt tgagaccgat cgaccctcct ttactagcaa tgggcattgg cagtgttagc
     6301 tctccgcata agctattttt agataaatca acgtgccagc tacttagccc tctataagag
     6361 ccagtccttg cggcataggc atgtgctcca gcctcaatag ctctccagtc atttccggta
     6421 gctatagcta ccgcatcgat tccattaaag attcccttat tatgcgttgc tgctcggtaa
     6481 gggtcaatct gggctaattt gcttgccagc tctatttttt tggccaattg ctgagcttct
     6541 tccttatgtc gacttaggta tctgaggtca acctgacatt tagcactaac taaagctttt
     6601 gttgcatagt ttgagaggat agccattaag cattgaccac cgcttagggc ctccaaatca
     6661 ggtactaaag cctccatcat cgtgttaacg atgttggctc ccatagcctc ttgggtatca
     6721 acgctcagat agacaatgaa aaaatcctcc ttacgctcaa cggtaaggct ctttgcgcca
     6781 ccaccacgct taacaataga agggtaggca ttgtttgcaa cgtcaatcaa tgtatctgcg
     6841 ttagctagaa tagccagcct agcctgctcg tcatctttaa catcataaag agctacctgc
     6901 ccaagcattt gacgactgag tacctcagtc tgaaagccac ctgatcgctt gatgattttg
     6961 gcagcaaagg aagcagcagc aacaacagaa ggctcttcag tcacaaaggg gacctgatag
     7021 gtatgcccat tgatcagaaa atcaggggct agactaaaag gcagagccag tcgaccgatg
     7081 acattttcgg tcatttgatt ggcaatagca atgggtaaga gctggtctgt ctctaacagc
     7141 ttttgctgct gcgggccaag cagctggtca tctgcgagct gttgaatgcg ttctgcaagg
     7201 ctttttttat aaaagccggc ccaatttggt ttagtttttg tcatcatctt gataaattcg
     7261 ttggtgttcc ttaatttctt tgagggcaaa cctgccagtt agatatggtg aaaagctggc
     7321 attgccatct tggtctagtc taggctcttc ataaaaaagt gcttcataat cagccactga
     7381 aatcacctga cgttggtcta atagggcttg tcgattagtc agtagcatgt ccttgtaacc
     7441 gtcaacaagc tgccctgaaa acagctcact aacagctcct gagccatagc taaacaatcc
     7501 aatcctatca ccagccctta gcacctgact attctctaaa agtgataata agccgaggta
     7561 gagtgagcct gtgtaaatgt tgccgatttg cttgctgtag gcaatagaag cttgaaagtt
     7621 ttcataaagc ctttctttgt gatcatctgc tagtgatttt gtcatgatct tatgaagtcc
     7681 ctttagagca agctttggaa aggggatatg aaaacaaaca gcagcaaggt ctgatagctc
     7741 aataccttct ttttcttggt atttgtccca ggttgttttt agggaatcaa ggtattgctt
     7801 ggtcgaataa ataccattga caaatggtgt tgagctgtaa tttggacgcc aaaaatccat
     7861 cacatcacgt gtctgtgcga cattgtcatg atttaactgg agaatacgag gattagtagt
     7921 aactagcata gcaatacttc cagcaccttg tgttggctct ccggcggatc caatgccgta
     7981 tttggcgatg tcactggcaa tgaccaagac cttggaggct gggtgtgcag caacatgtaa
     8041 tttggcataa tctaaagcag cagtagcgct gtagcaggct tcctttatct caaaggagcg
     8101 tgcaaagggc tgaatatcaa gcagctgatg aacgtaaata ctggctgcct ttgattgatc
     8161 aatgcttgat tcggttgcta aaatgaccat gtcaatgctt gctttatcgt ctttggtaag
     8221 gatttggtca gcagctgatg cagcaagcgt tacaatatcc tctgtaacag gtgcaatgct
     8281 tagagcgtca agcattagcc cctgatgaaa ttttgctgga tcagtgctgc gagcaagtgc
     8341 caggtcttcc atttttaaga cgtattgact ggtcgcaaag ccaatcttat caattccgat
     8401 gttcataaat atccttcttt tatccatttt atagtcctat ccattttatc atattttctt
     8461 agaaaattag ctgatttaat acgatagttt tacctttcaa accaaaaaca gcagcatata
     8521 gctttcttct ggtatttttg aaggaaatta gataaaataa tatggactgt gcttacagaa
     8581 aggggtttcc atgacaaaag cagatcatat ttttaaagct aatatcaaaa aaattatgga
     8641 ggagggagtc tttagcgagc aggctcgccc aaggtacaaa aatggtcaaa cagccaattc
     8701 caaatacatt acaggtgctt ttgcagagta tgatttgtct aagggagagt ttcctattac
     8761 aactctaaga tcaatcccta tcaagtcagc tattaaagag ttattttgga tttatcagga
     8821 ccaatcaaac agccttgatg ttttagaaaa caaatacaac gttcactatt ggaatgagtg
     8881 ggaggtcggt cagacaagaa ccatcggtca gcgctacggt gcaatcgtta aaaagcatga
     8941 tatcatctca aaaatcctca agcagctaga ggacaaccct tggaatcgcc gaaatgtgat
     9001 ttctctgtgg gattacgaag cctttgaaga atcagaagga ctgctaccat gtgcctttca
     9061 ggtgatgttt gatgttaggc gagtagatgg tgagctgtat ttagatgcca cgctgaccca
     9121 gcgctcaaat gatatgctag tggctcatca tatcaatgcc atgcaatatg ttgccctgca
     9181 gctaatgatt gccaagcatt ttggctggaa ggctggtaag ttcttttatt ttgtcaataa
     9241 tttgcacatc tatgacaacc aatttgcgca agccaaggag ctattggagc gtcagccagc
     9301 agcctgtcag cccaagcttt tgctgcatgt tcctgatggg acagactttt ttgatataag
     9361 accagaggat tttgagctac aggattatta cccagtgaag cctcagctca cctttgactt
     9421 ggcgatttaa gcgaaaaaga cgattttttc tgagcatttt gccaagaaat ttgatagaat
     9481 aaaagaagtt catattgagg aaagctagtg atgacaaaga agattattgc tatttgggca
     9541 gaggatgaag caggacttat cggagcgtgt ggcaggcttc cttggtacct accaaaagag
     9601 ttgcagcatt tcaaggaaac aacattgaat caagctatcc tgatgggacg agtaaccttt
     9661 gagggcatga agggtcgttt gctgccaaat cgccaaacgc ttgttatgac cagagacagt
     9721 tattatcatg tggagggcgc tttaaccata accagtgtgc aggaggcttt ggattggtat
     9781 catgcgcagg ataagacctt atatgtgatt ggtggcagca aggttttaga ggcctttgat
     9841 ggttattttg atgtcatcat caaaacagtg gtacatcacc agtttgaggg tgatacctac
     9901 cgacctaggt tagagctgag tgattttgta gaggagacct ctgtattgta cccaagggac
     9961 gataacaatc cttacgattt cactgttaca gtattgagac atcgctaata tagggagatg
    10021 atagtctatg cagcgtagta tttttggggt atttacggcc tttttgtgtg cgatttgtgt
    10081 tttatgtgcc ataccggcct ttagaaaaaa tcgctatggc ttaggattac tttttttatt
    10141 aaatgccttt actaacctag tgaataccat acatgccttt tatggaacac tgttttaagc
    10201 ctaagagaat gaaaagagaa agatagagga atcatggcag gaaatcgtag taacgatatt
    10261 aaggttcatt gctcgttttg cggcaagagc caagacgaag tgaaaaaaat tattgcaggt
    10321 aataacgtct ttatttgtaa cgaatgtgtt gccttatcac aagaaatcat caaggaagaa
    10381 ttggcagaag aggttctcgc tgatctgact gaggtaccaa agccaaaaga gctgcttgag
    10441 attttaaatc aatacgtcat tgggcaggag cgtgctaaga gagccttatc agttgcagtt
    10501 tacaaccact acaagaggat ttcatttact gagagtcgtg atgatgatga tgtggatttg
    10561 cagaagtcca atattctgat gattggacca acaggctcag gaaagacctt tttggcacag
    10621 accctggcta agagtctgaa tgttccgttt gctattgctg atgcaacctc tttgactgag
    10681 gcaggctatg tcggagaaga tgtggaaaat atcctcctga aattaattca agccgctgat
    10741 tacaatgttg agcgtgcaga gcgcggcatt atttatgttg acgaaattga taaaatcgct
    10801 aaaaaaggtg agaatgtctc tatcactcgt gacgtatcag gagaaggtgt ccaacaagcc
    10861 ttgctaaaaa tcattgaagg aacggttgct agtgttccac cgcaaggtgg tcgtaagcac
    10921 ccaaaccaag agatggtaca gattgatacc aaaaatatct tgtttatcgt cggaggcgcc
    10981 tttgatggta tcgaagaaat tgtcaagcag cgcttgggag aaaagatcat tggctttggg
    11041 caaaatagtc gaaagattga tgacaatgct tcctatatgc aggagatcat tgctgaggat
    11101 attcaaaaat ttggtctgat tcccgaattt attggacgct tgcctgttgt ggcagcgctt
    11161 gagcagctta atactgagga tttgattcgt attttaacag agcctagaaa tgcccttgtg
    11221 aagcaatatc aagccttatt gtcatatgat ggcgtagagc ttgagtttga aaagggggct
    11281 ctggaggcta ttgcaggtag ggctattgag cgcaagactg gtgcgcgtgg tctgaggtct
    11341 attattgaag aaaccatgct ggatatcatg tttgaggtgc caagccaaga ggaagtaatc
    11401 aaggtacgca ttactaagga agctgtcgaa ggtcaatcaa agcctatttt agagatagcc
    11461 taaggaggta tgatgtctga agagcaaatc cttaacacgc ataatgcttc gatattgctt
    11521 agtgcggcaa ataagtctca ttacccacaa gacgaccttc ctgagattgc tttggcaggt
    11581 cggtcaaatg ttggaaaatc aagctttatc aatactatac taggacgtaa aagccttgct
    11641 agaacctcaa gcaaacctgg taaaactcag cttcttaatt tttttaacgt tgatgataag
    11701 ctaaggcttg ttgacgttcc tggctatggt tatgctaagg tatctaaggc agagcgggct
    11761 agatggggaa agatgatcga agagtacctg accacacgac aaaatctcag agcagttgtt
    11821 agtctggttg attttcgcca tgagtcatca caggacgaca ttcagatgta tgagtttttg
    11881 aagtattatg agattccggt gattattgtg gctacaaagg cagacaaggt tcctcgtggt
    11941 cgctggaata agcatgagtc tatggttaaa aagtccttaa actttgatca aacagatgcg
    12001 tttattattt tttcatctgt tgagcgtatc ggtattgatg agtcttggga taccatttta
    12061 gagtatttat aagcatatgg taaaaaattt aagtatcttt tagacaggca cttgtgtctg
    12121 gtctgagagg tgctttttta ttgacaaaaa aacaatttgt tgatgacgag cttgtgttca
    12181 aaaatgtcag tttgctaaaa aatgatgata acaaacaaga cttttatgat ataatgctta
    12241 gcaggataat atggagacat gagaaaaagg tcagagacag ctaatttgct atccctgatt
    12301 ataactatga tgaccagcat tattataata ctcatggtgc tagctattag tagcagcacc
    12361 taacctatag tgttgctttt taggttacaa gcactggcgc taggagtatt ataatatatt
    12421 tagaaaggtt tttttatgac aataaaaaaa tgccctcaaa tacttgcctt attccttgct
    12481 tttgcagcgc tagctagtca ggggcaaacc gtccatgctc tggagcggca ggagacatct
    12541 gtcaagcaag ctcatgaatc agatgattgg tttgatgagg acgaaggagt tagcgatatc
    12601 aagtctaata cccctacaga gatagactca acagtaacag agttatttgg tgatgctgag
    12661 cctaagacta aggctgaaaa agaagagtca aaagctccaa gccctaagca agaagcactg
    12721 ccagcagagt ctcaaaaaga aaaagagaca tctgctaaat cgactgacca tgcgacagta
    12781 caagcagaag aggcacagcc tgagcaaggc tcagatagtc cttggctagc agatgacttt
    12841 gttactaagg gagatacctt ggttgggcta tctaaggcag gtcttgctaa gttatcaaag
    12901 acacctgtct tggtactacc aaggataggg attgacaaga cagtgttgac aaggattgct
    12961 agctttgcct ttactccaaa taaatcagtc gctattgctg attatacagg tagagcaggt
    13021 gaacatggcg agatcaatca tctggacgtc gaaggcagag atatccttac tgagggagag
    13081 gattttggtg cctatgcgat taaaaagctt gtgattcctg aaggctatct ttttatcggt
    13141 caagatgcct ttaatgacaa taaacagcta gaagaaatca gtctacctga tagcttactc
    13201 agtatttcag actatgcctt tgctcacatg agtttatcta agcttaagct gccaaaaagc
    13261 ctacagtcca ttggagatca agcctttttt gataatcgga ttgcaggcac tttggtattg
    13321 ccaaaagctc taaagcagct gggagaacgc gtctttaagt ccaatcgcct cactggactt
    13381 gtctttgagg gagaaggctt gtctgtccta aaagaagcag cctttcaaga caatgctttc
    13441 attagtcttg ttatcccaga tagcattcaa gccttagaag aggacgtctt tacaggaaac
    13501 cttggcgatg aagaatacgg taatcatgcc gttttacgaa ccaaaaatgg tcagaatcct
    13561 tacagacttc acagtgccaa tgttcttgtc aatccaagtg atcaggctag aacaccacag
    13621 ccaccaattg attacaacag gtggcttgca gaagatttta cctatactgg acagacgata
    13681 accggttttt cagctagtgg actgcgcaag gtcaaacgca ataagcattt ggttctgcct
    13741 aagaattatc agggtcagcc cttgacagcc attgcagata atgcctttag aaatgtcaat
    13801 tttcatgata aaaccttgcg taaatacgac ctagaaagcg tgacgttacc atctaccatt
    13861 caaaagattg gtgcctttgc ctttcagtca aataatctag aaagctttga ggccagcgag
    13921 gacttggttg agattggtca aggagccttt atgaataatc gcattgagat tctggccttg
    13981 aatgataagc tgaaggtcat tggagatgcg gcctttcata tcaatcggat ttatgctatt
    14041 gttatccctg agtcggtcga agtaattggc atttctgcct ttaggcaaaa tggtgctaaa
    14101 catgtgatgt ttatgggaga taagctaata agtattggag aaatggcttt tttgagcaat
    14161 actctggagg aagtggattt gagcagctta gcagggctta agaccatcgc tgttcaagcc
    14221 tttgcagaca atcacttgag agagcttaag ctgccagata gtttgatgcg tattgaagca
    14281 gaagctttta aaattaatag acttcaaaga gtgaccgttc cagacactgt cattagcatt
    14341 agctttaatg cctttgatca taatagtgat gacaaggttg tcctaaggac caccaatcac
    14401 aataaaaacc tgctagctga tggaaatggc tttattgtgg atccagacct attaagtgcg
    14461 gatcaatcga ctgttcaagc agttttagag gacctgcggc gcttagatct agctagtcta
    14521 cgtgctgata cagcagctca ttttatgaca ctcatcacaa gaggtaagca gctactaaaa
    14581 gaatccgctg tacggttagg ttatcagctt aggttccttg cagagtcacg atttttctta
    14641 gggcgcgtga gactggatca gctgattaaa actgctgaca taaccctatc tagccatcaa
    14701 gacacaccta atgctaagct gttgatggct aagctagaca aggccaagct gcattacaat
    14761 aatagcgcaa tgactgctcc aaaagtaagt cgcttggaaa aagagctcag cctgttaatt
    14821 gatcttgtcc aaggggtagg cgctatctct aaagcaacaa tgactcaagg tgtctataag
    14881 cttcagacaa ccctacctat tccagagtat tatattgggg ttaatcttta tactgatgat
    14941 caggggaata ttttatttgt gcttgacatg agtgatacga ttgggcaggg acaacttgat
    15001 gactatggca atcctatttt aaatgttgat gaggataatg aaggctacca tgctttggcc
    15061 attgagtcct tagcagatta cgaaggcctt acgattaagg atatattgac caaggagcta
    15121 aatcaattgc ctattcgcga tgtcaagcaa gcaagagagc atcgtgttgg tctttttatg
    15181 gcaatcagag atgctgcaag ggaagctcag cttctactag aaaagcagag caaagcctta
    15241 tcagaatcag ccggcaaatc taatggctca aaagtagctg actcaggact tgagccttct
    15301 gtgacactat caaccaataa gactaagctg ctaccaaaaa caggagcctt caaagaagct
    15361 tgggtgacaa tgatcggaat gcttgttctt ttggcggcta ccctacttaa aggcgatagt
    15421 cgctacaaaa agaagtaaat aggcttgctt agcaagcaca ctctagcacc agtaaggctt
    15481 gaggggctta caaagcctat ctaatctagc aatagtatat tgccagtgtg agctggtgct
    15541 tgagcttcaa aaaaacaaaa gagcctgaaa tgacttttac tagcatttca ggctcttttt
    15601 agcttgtgat tcttttttgt gtgaagctta cttctcactt atcgtaatag tatcttgatc
    15661 aaggcttgct aataggtgtt tagcagtcgg gtgatccagg tagtaatccg taatgcggtc
    15721 acgaatttct tgttcgatga cacgtctaag tggacgaact cccatcgcat gatcatagcc
    15781 cagatcaatc aaacgctctt taacatcgtc agtcacctca aggctaatgc cttttttagc
    15841 aagggtttgg ttcacttctg ttagcattaa agcaacaatt tcttgtaaat cctttttcgc
    15901 taaatggttg aattcgatga caccgttgaa gcgattcaag aattctggtc taaagtaagg
    15961 tgcaatacgc tccatgatag caggctcttg atcagcacga tctcctgctt gatggccaaa
    16021 accagcatta gaggttgcga tgataaccgt atttttgaaa ttgatcgtgt tgccttgtcc
    16081 atctgtcaat cgcccatcat caagcacttg aagaagcagt gtaatgacct gtgggtctgc
    16141 tttttcgatt tcatcaagca agatgataga gtaaggactg cgacggacac gttctgtaag
    16201 ggtattttga ttatcatcat agccaacata gccagctgtt gttccgatta atttggaaac
    16261 agctgtgcgg tcactatatt cagacatatc taagcgaatg atagcgtcct ttgagccgaa
    16321 catatcaagg gctaactgct tagccagctc ggtcttacca acaccagttg gaccaacaaa
    16381 gaggaaggag ccaattgggc gattaccgtc atcaaagcct gcgcggttgc gtcgaatcgc
    16441 acgagcaaca gcctcaactg caccatcttg tccgataaca tggcctttaa gacggttact
    16501 gatttccttg agcctttcta aatcactagc ccccatattt gatactggaa caccagttag
    16561 acgttcaaca gattctgcaa tatcattaac agtggcagtg accttttgcc cttcactgtg
    16621 atgattgatt tgcttttgga gctcctcaat gcgggtctta gcagttaagg ccttttcaaa
    16681 gtcttcttct gcaacagcct tttcctgtag ctccttttgc ttagtgattt ctgcttcaag
    16741 tgattttaga tcagtgacag ggtgctgagc tgctagatga gcagcagtca tatcaacaag
    16801 gtcaatggct ttatctggta ggcttcgttg tggaatatat tggatagcat aatcaatagc
    16861 tgccttcaag acagagtctg gtaggatcac attgtggtgc tgctcgtaga ggttgcgaat
    16921 gcccattaaa atgtggaagg tatcctctgc tgaaggagca ttaaccttaa cctcgttgaa
    16981 acgacgagca agagcagcat tttttagaat ggtgttgcga tactcatctt gagttgtggc
    17041 accaatcagg gtcaactcac cgcgtgagag ggctggtttt agaatatcag ctaagccctt
    17101 agagcctgag tctgaaccag ctgaccctgc accaaggatt tgatggattt cgtcaaagaa
    17161 gagaatgata ttgccagcct ccttaacctc tttaaccatg ttttgaatgt tttcttcaaa
    17221 ggagccacga tactgtgtgc cagcctcaag gccagaaata tcaattgaga taatctcttt
    17281 atttttgatg gcagctggca catcaccgtt gacaatagcc tgggctaggc cttcgacaac
    17341 agcagtttta ccaacaccag cgtcaccgac aagaacaggg ttattcttgg ttcgtcttgc
    17401 tagaatttct gcggtcgctt gaatctcatc gtttcgtccg atcacaggat ctaacctgcc
    17461 ttgccgagct tcttcggtca ggtttgttcc gagcttggtt agaatgccgt cttttttaag
    17521 gctgctagcc tgtttttctt gtccctcagc tgcagctagc ttaccggttt tccggtattc
    17581 ttgaaattcc tctggtgtca tctcacgtcc attgacaaga tagcgacgat tttcgctgcg
    17641 gtagccgccg atgtttccca ttaactgatt gaaaatatcg tccatatttt caaaggggtc
    17701 ttttccataa taggttgcca tatacactta cctcacttgt attatattta ccagtcatta
    17761 tgagctactg gtataggtag aaggtgatcg gtgttggctc atacagagat catagagagg
    17821 tcttatgaga gtctattgct caggcttatt actcaccttc taataatatt atatccaaaa
    17881 ggtcagtaaa ggtcaaacaa aaagtatgaa taattaacct ttataatcag gtgcttatag
    17941 cccttgaaac atcagatgac tatgccataa gctgctggtg cttttttgct agcaaggcta
    18001 tctgtaaaga agagactttt gtcaaaaatg gttttacttt ttgttctaaa ggctttcatg
    18061 atataataaa agaaaagcac agaggtcaat tatggaacaa acatttttta tggtgaagcc
    18121 tgatggtgtg aaacgtggct tggttggaga gattctacgc cggattgagc gtcgtggctt
    18181 tacctttgat aggcttgaat tgcgacaagc aaccccagaa ttgctagcta agcattatga
    18241 caccttaatc aataagccct tttatccaga gctagaggcc tatatgacaa gcggacctgt
    18301 tttaatcggc attatctccg gtaatcgtgt ggtctcttcc tggcgaacca tgatgggggt
    18361 aaccaatcct aaagacgctt taccggggac tattcgtggt gattttgctc aagcccctgg
    18421 tgatgatggc ggcattttca acgtggtgca tggttcggat tcgagagatt cagccaagcg
    18481 agaaattgcg atctggtttg gacatagctg acattgggct tgggcctatt cttttaagaa
    18541 ctgataaagc aattgcataa ggagttgata agcccatcat caatagtagc tcagcattag
    18601 aagggtaaca gccttgatgt tgggctattt ttttgcttgc ctagggtctg tatgcttgtc
    18661 ctgatgagca ggtagacaaa gcagcataag tttaacaatc ctttgcggca gtgatcaatt
    18721 gtagctctaa ccatagcatc agctatttga aagccttgaa aaagaaagct aaggctaaca
    18781 agctagtcta ggtcatttac tacaagcgac ttttttcaat tagctgctca aggcaagtat
    18841 tgaaaaaagt ccatttttca tgtcatttgt aataatatgg tatattttta acgaaaagtc
    18901 gttttagttg agaaaatata caaaaaaggc tatgatatag ttaataaagt tgttataccc
    18961 cctgtgtctt gtacactatg acttgtagag agtttatcaa aggaggataa gatgaacaaa
    19021 caaagcatga cccatttttc taagaagctg atgaagttag cccttttagg tttggcattg
    19081 ccattaagct tggtgtcggt ggtagatact ccggttctta accaatccga aaaagctgtt
    19141 tatgccaatg attttggatc tggaaatcga gccagtgatt atgtaccggc ggctaacgct
    19201 tggagctttg aggcttatcc agattactac agtattttag gagctagtca tcttaatcct
    19261 gctgtctttc cagagcctag taagatgtca tacagtcctt tagacgagtt gggccgcaca
    19321 caggtcgcaa gaggaacaat aacctatcac aatatcgtga tgaattacaa tgttcggcaa
    19381 cgctttgcta aaaatcagaa cccttcaggc tggattggta accctagaaa tgttcgctac
    19441 actattgagt ggctagatgg actatcctat cagggagatt tttggaatcg gagtcatttg
    19501 attgcagata gccttggtgg agcagcctta cgtgtcaatg ctattactgg tacaagaaca
    19561 caaaatgttg gcggcagaaa tcaaagaggc ggtatgcgct atattgagca aaaggtgcag
    19621 cagtggattg agcagcatac aagcgcagtt gtttattacg aagcggtgcc aatttaccag
    19681 gcaaatgagc tagttccaag agctgttgtt gtttcagcat tgtcatcaga cggaggtctt
    19741 gacgaaaagg tcatggtcta taataccgcc aacggctata ccattgatta tgccactggc
    19801 gcattccgca gtaactaggc ttttgtacta agctgtagct gatcaaggtc tgactaagac
    19861 aagctcatca gcaattggta tataaaaaga cgtggcaaca acatgtttta aatgagttgt
    19921 catgtctttt tagtgtcgtc agcttttcac attgtcttag aatgatcaca cctagctagc
    19981 cgctaaaagc attggtccaa agaaatgtta agaatagata gaatgccttt taatcagtgg
    20041 tatgggactg ctagctaata taatgcctgc agttgagcca atttctcatc taggctaata
    20101 actaacaagc tattgactta tcgtgttcat tagaatgtca gctgttgtag ttggtagtat
    20161 tcgaatacga ttaagcgata gcaggccatt agcagcactt gctagtcctt catttgttgt
    20221 gacccctaat ttgtaatgca gatcctcagc aatctttaat gtggtatcag tataacgacc
    20281 tgctggatag gcaattgcaa tggtatcttg gtgtagctct ctatctaggt attctttaga
    20341 atctttcatt tcagcggttt gactagcagc gcttgcctga gatagatcag ggtggttaac
    20401 cgtatgatct tggaaagaca tgcctgcctg cttcatttcc ttcatctgat ccaatgtaag
    20461 attggccgca ttacctgcct ctgtaaagcc agtgataacg ttattggtgg ccttgatgtc
    20521 atactttttc aggattggaa aagcaacgtt gtaaaaatca accatgctat catcaaaggt
    20581 tagccagaca accttttcag caggaagctc gttagctgat aagactcggt aggcttcttc
    20641 gggagataaa aagtagtagc cggcctcctt cattgccttt agctggcttt caaaaagatc
    20701 tggagcaacg atgagattgg cacttgctgc ctcttctggt gccataacgt gaatagcatg
    20761 atacattaag ataggaagct taacagggtt ttgctgcttg gtccagctga cagctccttt
    20821 ttgctgctga ctatttgtat ggctagcttc cttattagtt gcttttttgc taggcttggg
    20881 agctggtttt ttatcagttt ttgaaaatag gcttattttg gggattgcct gcgataattg
    20941 agagatgctt atctttgaat ggctcttgta aaggtagaca atagctgata agcctatgat
    21001 acaggcaagt agtagcatga gattaatcat tttgaagatt tttcttttct tacgccgttt
    21061 gtttctgttg ttcatcactt gctccttgtt tattgattag tctattgtaa cattttttta
    21121 agtaagctgt ctttcgttaa cttaattttt tgctaacatt ctattagtgt tatgctttgt
    21181 aaaacaagac ctagatttgc tataataaga cagagtattt aagacagtca aaaaaaggag
    21241 gataggatgt cagttaaggt tgcattatta ggctttggga ctgttgctag tggcattccc
    21301 ttgctattag aaaacaatag tagcaagatt cgtgcagtgg taggtgatga tttggtgatt
    21361 gcaaaggttc tggttagaga tgagaccact aagaagcgtt tgttggatca aggctattcc
    21421 taccaatttg tgacctccat tgatgatatt gttgatgatg agagcattga tatggtggtc
    21481 gaattaatgg gtcgtatcga gcctgcaaag acctttatct cgcgtgctct atcagccgga
    21541 aagcctgttg tgactgctaa taaggatttg atagccttgt acggaggaga gctctcgact
    21601 ttggcagcta agcatcaggt agctttgtac tacgaggctg ctgttgctgg tggtattcca
    21661 atactaagag ctttggctga ttcctttgcc tcagataagc tgacgcgtct gctcggtgtg
    21721 ctcaatggaa caactaattt catgttaacc aagatgattg atgagggctg gacctatgaa
    21781 agggccctgc aaaaagcgca ggagctgggc tatgctgaaa gtgatccgac taatgatgtg
    21841 aaagggatcg atgcagctta caaggttgct attcttagtc agtttgcttt tggaatgacc
    21901 attgactttg aggctattag ctattcaggg attgataagg ttcgagtaga agatgtgaca
    21961 gtagcgcaga agctgggcta tgtgatcaaa ttagttggtc tacttgaaga gacggcttct
    22021 gggcttaacg cagaggtatc cccagtcttt ttaccaaaga cacacccgtt ggctgctgta
    22081 gacggtgtga tgaatgctgt ttatatcgag tcaattgggg ttgggcaggc tatgttttat
    22141 ggtccaggtg ccggtcaaat gccaacagct acagctgttg tggcagatat gattcagact
    22201 gcctgcacct tacgtgacca tacagtctca gtctttaatc gttttgctac aaaaactaga
    22261 ctagctaagt ctgaggatat tatgagtccc tattactttg ctattcaagc aactaataag
    22321 tttggtcagc tactagagct aacaaggcta tgtgatgttt gtggcattag agttgagcag
    22381 ctgttatcag atgagataga tagtgacagg ttagactttg tgatgattac tcatgagatg
    22441 agcaaaaagg agcttgcttg ctttacagcg ctactacagg atcatcagga tttccgtatg
    22501 ttaagtacat ttaagatttt aggagattga catgaagata cgcgtacctg caacctcggc
    22561 taatttggga cctggatttg actcaatggg gattgctgtt tcaaaatacc tagaagttga
    22621 cattttagaa gaacgtgacc aatggtttat tgagcatgat ttgggtgata ttccaaatga
    22681 tgatagcaac ttacttatcc aaacagccct taggctagca ccaaatattc cagcacatcg
    22741 tctaaagatg acgtctgata ttccattggc acgtggcttg ggatcgtcct cctcggtgat
    22801 tgtcgctggt attgaattag ctaatcagct agggcattta aacctaacag acgaccgtaa
    22861 attggccata gcaactcgta ttgaggggca ccctgataat gtagctccag cgatttttgg
    22921 tcaattggta attgcttcac agattggtaa ggacgtggat tacatcattg cgccttttcc
    22981 tgacctttct ttggtttgtt ttattcctga ttatgagctg aaaacctctg attccagaga
    23041 tgtattgccc aagcagctat cgtataagca ggcagtggct gcttcctcag ttgctaatct
    23101 tgctatagct gcgctattga ccggtaattt gaaaaaggcc ggtcgggcga ttgaaaatga
    23161 ccaattccac gaaatctacc ggcaaagatt agtcagagag ttccagccga ttaagcgagc
    23221 tgcagcagct aatggtgctt atgcaaccta cttatccggt gcagggcctg ctattatggt
    23281 tatgtgtccc aataagaaaa aaatggcgat ttatgaggcc atcgagcagc taggtctaat
    23341 tggtcagttg gtgtctctag agctggatcg tcaggggctg tgtcttgtct agactggcaa
    23401 ggtactggta tgcttgccta gtaggcttat tgttgatatc agatggactt aaagcttagt
    23461 cattcaaata catcaaaaaa gtgaggcttg atcgttttat cggctttcac ttttttcttg
    23521 atatgttata ctagagtaga ctttgtgagg tgtgtgatga attatcaaga aacattagac
    23581 tggattcatg gtcaggaaag atttgggatc aagccaggtg taaaacgcat gcgttgggtg
    23641 cttgagcagc taggtaatcc tcaagatagg attagaggaa tccatgtggt cggcacaaat
    23701 ggtaagggat cgacggtcaa tgacctacag catattttta ctagagcagg ctatgaggtt
    23761 ggaaccttta cctcgcctta tatcatggat tttaaggaac gtatctgtct caatggtgag
    23821 atgatctcag agactgacct tgttaaggct gctaattgta ttcgtccact aacggatcgc
    23881 cttatcagtg agacaagttt gggtcctgca acagtctttg agctgatcac tctgatcatg
    23941 tttctttatt ttggtgagag tcacccggtt gatattgcta ttatcgaggc aggattaggg
    24001 gggctttatg actccactaa tgtgtttcag gcgatggctg tggtttgccc gtctattggt
    24061 cttgatcatc aagctatttt aggtgatacc tatgctgaca ttgcctatca aaaagccggt
    24121 gtgctaaagg gtggtgaaga ccttattttt gccattgata acaaagaggc cagacaggtt
    24181 tttctaaaaa aagcagagca gcttggcgtg cctatttggg aatggcgtcg acagttcaac
    24241 atgctacagg gtgaaggtgg ttatcaattt aacagtcagc ttggtcagct gtctcatcta
    24301 gtgcttgcaa tgcctggtca gcatcaggta gccaatgcag gcctagccac tatgacaagc
    24361 ttgatattac aggatcggta cccaaaggta actgagtctg ttattagaga ggctctggca
    24421 agcagctttt ggttgggacg aacagaattg ttggcaccca acctgatgat tgatggtgct
    24481 cataataatg aaagcattgc cgccctgatt gatgtgatat catcagacta tcaggataag
    24541 cagattcata ttctatttgg tgccattgat accaagcctg tctcagatat gctgcagagt
    24601 ctggagcgtc ttggagatgt gcaagtaaca agctttcact atcccaatgc ctatcctttg
    24661 gaggcttatc cagataggct aacaaaagta gcagatttta gagcattttt agaccggctt
    24721 gagcaagcag ctgctgatga ttttttcctg attacaggct ctctttactt catctcagag
    24781 gtcaggcagt attggaaaaa ggtattaagc aagtaatgct ttctcacatc aactcatcaa
    24841 acaagattaa tcaactaaaa aggggaaaac cattgccaat caatcaaaaa aaagcagaag
    24901 ccgctatcta tcaattatta gaagctatcg gtgaggatcc aaaccgagaa gggctacgag
    24961 ataccccaaa gcgtgttgcc aagatgtatc tagaaatgct ctcagggctg gaacaggacg
    25021 ctaaggatga atttacagct gtttttacag agcatcacga cgatttggtg attgttaagg
    25081 atattagctt ttattccatg tgtgagcacc atctggtgcc attttatggt aaggcgcata
    25141 ttgcttattt gcctagtgat gggcgtgtga caggcttgag taagctggca agggcagttg
    25201 aggtgacgag caaaagacct cagctgcagg agcgtttgac agctcagatt gctaatgctc
    25261 ttgttgatgc cttgcagccc aaaggggttt ttgttatggt agaagcagag catatgtgca
    25321 tgaccatgcg aggtgtcaaa aagccaggca gtaagaccat tacgacaact gctagaggga
    25381 tttacaagga tagtagagac gacaggcgtg aggttatgca attaatcatg gagggctagg
    25441 gtatttatga ctattggaca ttattcagcc gctggtgagg cagctattat ggggatttta
    25501 aatgtgactc cggattcgtt ttcagatggt ggctcctata ctagtgttaa tcaggccttg
    25561 gcacaggccg aaaaaatgct gtcagaagga gcgactgtca ttgatattgg aggcgagtca
    25621 acacgaccgg gctgccaatt tgtgccggca gaagaagaga ttgcacgcgt tgttccaatc
    25681 ataaaggcca ttaaaaaacg gtatgatgtc cttattagca ttgataccta caagacagaa
    25741 actgctagag cggcccttga agcaggagca gatatgctca atgatgtctg ggcaggacta
    25801 tatgacggtc aaatgctaag tctagccgcc gaatacgacg ttcccattat attaatgcat
    25861 aatcaaacca aagaggctta tgctgatgtt acaaaagagg tttgcagctt tttacaggct
    25921 agagcagctg cagccctcaa agcaggtgtc aaaaaagaac atatctggct tgatccagga
    25981 tttggctttg ctaaaaatgt tgagcaaaat atagccttat taaaagggct aaatgaggtt
    26041 tgccagttgg gctatcctgt tctttttggg atttccagaa agcgtgttgt agacgcccta
    26101 cttggtggcg gcactaaagc caaggatcgt gacggggcta ctgccgccct atcagcctac
    26161 gctattaata aggggtgtca aatggtgcgc gtgcataatg tcggtgctaa cagggatatt
    26221 gtctctgtat tgagtcaatt aaggtgagaa atgatggata aaatcagatt agaggcttgt
    26281 cgcttttatg gttatcatgg tgcctttaag gaggagcagg tcttaggtca aatttttgta
    26341 gtggatttag aattatcagt tgacttgatg gctgcctctc tttcagactg cctagaggat
    26401 actgttcatt atggtttagt ttttgaaaca gtccgtcaaa ttgttgagga aaagaccttt
    26461 acgcttatcg aacgtttggc tggtgccatt tgtcaagagc tatttgccca gtttttgcct
    26521 attaaagcga ttaaaatcgc tattaaaaaa gaaaatccac cgattgcagg ccattatcaa
    26581 gctgtcggta ttgaattgga gagaaagaga tgacacttgt ttatttaggc ttgggaacta
    26641 atatgggaga tagggcaggc tacctacagg cagcagttaa tgccctatct aagctgccag
    26701 agactgagtt actgagacaa tcctctatct atcaaacagc agcctgggga aaaacagatc
    26761 aaaatgcctt tttgaatatg gcttgccagc tagatactag gctgacatca gaagctcttt
    26821 tggcagctac gcaggctatc gagcaggctc tgggacgagt tcgtcatgaa aaatggggcc
    26881 caaggacaat tgatattgac ctcttgctgt ttggtgatga gccgtatcaa tcagagacct
    26941 tggttattcc tcacccttac atgacacaaa gagcctttgt tttgattcct ttattagaga
    27001 ttgcacccga tgtgacctta cctggtagcc agaaaagcct gaggtcttac cttgatgctt
    27061 tagagcaatc agatgtagcc ttgtggtcac atgagtattc aaataagttt tcttaaactg
    27121 tcgttatttt tactaaaatt tgatataata gtgctactct ttgctgattt tttgtcttat
    27181 attaagaaat gattgaagaa agaagaagat tatgatagct gaacttgaag gcattgatat
    27241 tcgagagaat gaagccttaa aacattacac ctatacccaa gtaggcggtc cagcagattt
    27301 cttggctttt cctagaaatc attacgaact atcccgtatt gttgattatg ccaatcataa
    27361 tcatattcct tggatggtcc ttggaaatgc cagtaatctc attgttcgag acggtggtat
    27421 tcgtggcttt gttatcatgt ttgataagct caacgccgtc cgccttaatg gttatacctt
    27481 ggaggcagag gcaggcgcta acctcattga aacaacaaaa gttgccaaat ttcatagctt
    27541 aacaggcttt gaatttgctt gtggcattcc tggaagcata gggggtgctg tttttatgaa
    27601 tgcaggtgct tatggtggag agattgctca tatttttttg tcggccaagg tcttgacacc
    27661 agaagggaaa ataaaaaaga tctcagccag agagatggcc tttggctatc gtcactctgt
    27721 cattcaagaa actggtgata ttgtgatttc agccaagttt gctttaaaac cgggtaatca
    27781 tgacagtatt tgtcaggaga tgaatcgcct caaccacctt cgaaagctca agcagccctt
    27841 agaatttccc tcttgtgggt ccgtttttaa gcgtcctcct gggcattttg cagggcaatt
    27901 gattatggac gctaacctaa aagggcatcg tgttggcggt gttgaggtct ctaaaaagca
    27961 tgcaggcttt atgattaatg ttgctgatgg ctctgccaag gattatgagg acttaattgc
    28021 tcatgtcatt aggacagttg agcaggcatc tggcgttagg cttgagccgg aggttcgtat
    28081 tattggtgaa agcctttaat gattgtgtta tcaaaaaaga aaaattgtgg aggatttatg
    28141 acaattgact aagccaatta tcacatttga caatgtctca aagacatttg aggacagcgg
    28201 gacacaggtc ctaaagaaca ttaattttga gcttgaggag ggaaaatttt acaccctgct
    28261 tggtgcctca ggatctggga aatcaaccat tttaaatatt atggctgggc tgcttgatgc
    28321 gaccagtggt gatatttatt tagatggtga gcgtatcaat gatttgccga ccaataagcg
    28381 tgatattcac actgtttttc agaattatgc tttgtttcct catatgacgg tttttgagaa
    28441 cgttgccttt gctttaaagc tgaaaaaggt tgacaaacag gagatagcaa gacgtgtcaa
    28501 ggaaacctta aaaatggttc agctggaggg ctacgaaaag cgatccattc aaaagctttc
    28561 cggtggtcag cgtcagcgtg tagcgattgc tcgtgcgatt atcaatcagc ctcgtcttgt
    28621 cctattagat gagccacttt ctgcccttga tttgaaattg agaacagaaa tgcagtatga
    28681 gctgcgtgag ctgcagcagc gactgggcat tacctttgtt tttgttaccc atgatcagga
    28741 agaagcacta gcgatgagtg attggatttt tgtcatgaat gatggtgaaa ttgtgcaatc
    28801 aggcacacct gtagatattt acgatgagcc gattaatcat tttgtagcta gctttattgg
    28861 tgaatcaaac atcatcaatg gtacgatgat taaagactat ctggtttcct ttaacgggaa
    28921 agaatttgag tcagttgatg gtggtatgcg acccaatgag ccagttgagg tggttattcg
    28981 accggaggat ttacaaatca ccctgccaga ggaaggaaag cttcaggtaa aggtagatac
    29041 acagctcttt cgtggtgttc actatgaaat cattgcctat gatgatttag gcaacgaatg
    29101 gatgattcac tcaacccgca aggccattga aggagaagtg attggtttag atttcacacc
    29161 agaggatatt catattatgc gcctcaatga aacagaagaa gaatttgatg ctcgtatcga
    29221 agaatacgtt gaaatcgatg agcatgcgga tggcttaatc aatgctattg aggaggagcg
    29281 caatgaagaa aacctctagc ctctttgcag ttccctattt tttatggatt gtcctctttg
    29341 ttatggcacc ggttgccctt ttgctttatc aatccttttt tgacatcgaa ggacgattga
    29401 cactagccaa ttacgagact ttttttagct catggactta cctgagaatg ggcttaaact
    29461 ctatcttata tgctggtatc gttaccttgg tgaccttttt gatttcatat cccacagctt
    29521 tattgttaac gcgtttaaag cacaagcagc tgtggttaat gcttattatt ttaccaacct
    29581 gggtcaatct gctcctcaag gcttatgctt ttatggggat ttttgggcag cagggtggta
    29641 tcaatagctt tttaaccttt atgggcttag gaccacagca aattctgttt actgattttt
    29701 cgtttatttt tgtggcctct tatattgagc tgccctttat gattttgcct atttttaatg
    29761 ctttagatga tattgatgat aatattatca atgccagtaa ggacctgggt gccaatgact
    29821 accagacctt ttcaagggtt atttttcctt tgtcgctaaa cggtgttaga gcaggggttc
    29881 agtctgtttt tattcccagc ttgagtctct ttatgcttac gcgtctcatc ggtggaaatc
    29941 gtgtgattac gctggggaca gctattgaac agcatttcct aacaacagaa aactggggca
    30001 tgggctcaac cataggtgtt gtcctaatta tcgcgatgat tgtgattatg tggctaacaa
    30061 aggagaaaag taaatgaaaa aatttgccaa tctttactta gcgtgtgttt ttattttgct
    30121 ctatattcca atcttttact tgattgttta ttcttttaac aagggtggag acatgaatgg
    30181 cttttctggc ttgacgctag agcattataa gaccatgttt gatgatagtc gcttgatggc
    30241 gattttattg cagacctttg tgttagcctt tacaagtgcc ttgcttgcaa ccattatcgg
    30301 gacctttggg gcgattttta ttcatcagag taaaaagaag taccaaaatg cgatactgtc
    30361 tgcaaataat gtgttgatgg tttcccctga tgtgatgata ggtgcctctt tcttgattct
    30421 ctttacgtcc ttgaaatttc aattaggaat cctctcggtt ttgatgagtc atattgcttt
    30481 ttccattccg attgtggtct taatggtgct tcctcggttg aaggaaatga atcaagatat
    30541 gattaatgca gcttatgatc taggagcaaa tcactttcaa atgctaaagg aggttatgct
    30601 tccttatctg acaccgggca ttatcgcagg ctactttatg gcctttactt attccttaga
    30661 tgattttgcg gtgacctttt ttctaacagg aaatggcttt acaaccctgt ctgttgagat
    30721 ctattcgcgt gctcgaaggg gtatttcatt agatatcaat gccttatcaa cgattgtctt
    30781 tttgttctca attctattag tcattggcta ttattacatt tcacaggaca aggaggaaaa
    30841 gcatgcgtaa gctatactct tttttagcgg gaattatcgg ggttatcttg ctgcttgcga
    30901 ccctgtcctt tattttgcag aaaaaaacga gctctgctag tcaatctgat aagctggtga
    30961 tttataactg gggtgattac attgatcccg ctttgctgaa aaaattcact aaggaaaccg
    31021 gtatcgaggt tcagtatgag acctttgatt ccaatgaagc catgtacacc aagatcaaac
    31081 agggtggaac gacctatgac attgctgttc cgagtgatta cacgattgac aagatgatta
    31141 aggaaaagct tcttgttaag ctagataagt ccaagcttgt tggtctagat aacattggtc
    31201 aggagttttt aggaaaaagc tttgatccgc acaatgatta ttccattcct tatttttggg
    31261 gaacggtagg cattgtctat aatgaccagc tggtggataa ggctcctatg cattgggagg
    31321 atttatggcg gccagaatac caaaatagta tcatgctagt tgatggtgct cgtgagattt
    31381 taggtgttgg attgaccaca tttggctata gcgttaactc aaagcaccta aagcagcttg
    31441 aagcagctga aaaaaaacta caggccttaa cccctaatgt aaaagcaatc gtcgctgacg
    31501 agatgaaggg gtatatgatt cagggtgacg ctgctattgg tgttaccttc tcaggagagg
    31561 ctagcgaaat gctggacaat aacgaccatc tacactatgt tgtaccatca gagggctcaa
    31621 acctttggtt tgataatctg gtgcttccca aaacaatgaa gcatgaaaat gaagcctatg
    31681 cctttatcaa ctttatcatg aagccggaaa atgcagcaca aaatgctgaa tatatcggct
    31741 atgccactcc caatacaaaa gcgaaggctt tattgccaga tgatattaaa aatgacccag
    31801 ccttttaccc aactgacgag accgtaaaga aattagaggt ttatgataat ttaggctcta
    31861 aatggcttgg tatttacaac gacctttacc tacaatttaa gatgtatcga aaataggtca
    31921 tgcaagattg aaggagctat tcattggaaa gcttcttcag tcttttttag cttggtctgg
    31981 tctcaataat ctcatgagat taaaaagaac tagaatcttg ctttcgtctt tgatacaata
    32041 gtagtggttt attaaaatga aagagatgac aaaatggaaa atcataaaaa cgagtttacc
    32101 ttttccaaac attcaatcat agcctacgtt tggcgtggca ttttagtcgg gataattgct
    32161 ggagctattg tcagtttgtt tcgcttattg attgagatgg ttagtgaggc tgttgttggc
    32221 tattatcacc aagctcacag caatcgcatg ctccttgttc cgatagcagg ctttagctta
    32281 ttagctgttt ttttagttgg tcttttggtc aagtctgacg ccaacattaa aggctctggt
    32341 attccacacg tcgaagggga gctaaagggc ttgatgtcac ccaattggtg gagtgtgctt
    32401 tggaaaaaat accttggtgg aacaattgcc atttctatgg gcttaatgct tggaagagaa
    32461 ggcccttcta tacaattagg ggctatgtca gctaaaggct tagctaagta cctgaaatct
    32521 agtcgtctag aaaaacgtgt cttgatcgct agtggagcag ctgctggctt atcagctgct
    32581 tttaatgcgc ctattgcagg actgcttttt gttgttgagg agatttacca ccatttttca
    32641 agattagtgt ggatcactgc cttggttgca agccttgttg cgaactttat ttcgttgaat
    32701 atttttggcc ttagacctgt tttggccatg cctaaggcca tgccctttct tgccttacat
    32761 caatattggc tgctcttaat cttaggcctt gtgcttggct gtctgggctt tctttatgaa
    32821 gaggtcattt tacattttca tagggtttat gattttcttg gaaagagctt gcgcctagcg
    32881 ccgcattttc atgggctgat tgttgttgct attatcctgc tgattggcta ttatttgcca
    32941 cagctattgg gcggaggtca tggtttgatt atgtccttgt cagagcaaaa gctaccactg
    33001 ttgactgttc ttgcttactt ctttattcga tttttaggga gtatgtttag ctatggcagt
    33061 ggcctgcctg gaggaatttt tttgcctatt ctaaccttag gtgccttgtc cggaactatt
    33121 tttggattga ttcttcagca aataggactg ttagatcgcc agatgattcc tctcttttta
    33181 gtattgggaa tggcaggcta ctttgctgct gtatcaaagg cacccttgac aggaatgatc
    33241 ttagtgactg aaatggtagg ggatctgaag cccttaatgg ccattgctgt tgtgaccttc
    33301 gtggcctact tggtgatgga tttgttaaat ggtcagccta tctatgaagc aatgctagag
    33361 aaaatggcta tcaaacaccc aacagatcta gtggagccga ccctgatcga attacctgta
    33421 agtgagaaaa ttgcaggcag atatgtccga gacctgaagc tacctaaaaa cgttttaatt
    33481 acaacgcagc tccaccataa gaaatcacag gtcgtctcag gtgatacgct attgatttca
    33541 ggtgctacga tctttttggt ggtcaatgaa gctgatacag gctttgttcg agaggtcttg
    33601 atgtagagca aggtcggtta agcagtcagc agtagctgtg ctaccgatca aagaagcaga
    33661 tcagtgcttt ttctcatctg atgaaaggta ttgatttgct ttttttgtgt tattaaacct
    33721 ttgttagcaa gagccatagc cttagcagtc gtatctgatg aatacctgct gtctttttgt
    33781 tatacttaag tatcaatcaa aggagcttta tatgctagaa gttatttcaa aagagctgcg
    33841 ccattaccaa aagaataagc ttgccgccta tcaaaaaaag aaccaaggca tagaagctgg
    33901 tggaattgtt tttgctggcg attcgttaat cgaatttttc ccgttgaaaa aatatttcaa
    33961 acaggtctca accatttata atcgcggaat tgcagggata gacagtcagt ggttgctaga
    34021 gcatattgac agtcatgtga atgatctgga gcccagtcat gtgtttatcc tgattggctg
    34081 taatgatatt gggcttggct ttgatcaatc gcatatcgta tcgaccattg ttgatcttat
    34141 tagtcgtatt cgcagtcagt ctatttatac taggattagc cttctgtcct tattgccggt
    34201 ttctgaaaat cccgcctatc aggcgactgt caagctaagg acaaataggg ctattgatga
    34261 gattaatcaa gcattagcaa tgataccagc gattgaattt attgatctta acgcctgctt
    34321 aaaggacgag actggtggct tagcagctgc ttatacggta gatggcattc atcttaatgc
    34381 ccttggctat gaacacttag ctcaagctat tagtccctat ctatgaaagg taaaggctgg
    34441 agctgctaat ttgtaaggga tctttaaaaa acaagcactg atgaatcatc attgaaaccc
    34501 ttcagagtgc cgataggctg cacaatcaaa gaagcattag gtttgtctat gacgcccttg
    34561 tgttaagctg gcttttaggt ttatactgcg agaaaatcag tcattgggct gggagtctca
    34621 aagcttagct gtggtaatta aatgcgagct cctgctagct tgtgctgatc aagcagtata
    34681 gcaaggaggg actgaacttt tagtctcaga taatattaga ctttttatcc tatattaaac
    34741 gatttagtgt ataataaaca ggaaggagtt aaaatgaaat ttgaaaaaaa acaagtcttt
    34801 tatgttgtgc ttgcctttgt gctttgttat gctattcaag ctaattggga taatggggct
    34861 aatattgtca caaccgttta taagacaagc ctgccctttc tttatggagc agcagtcgcc
    34921 tatattgtta atattgtcat gagtgcctat gaaagagctt atacttatac cctaaaaccc
    34981 tttccttttg ccatgaaggc tagaagaggg ctctgtatgc ttttggcata ttttaccttt
    35041 atcagcttga tcgtatggat tatttctatt gtaatccctg atttgattgc aagcattagc
    35101 tcgttaacgc aatttgatac aagagctatc aaggaggtca tcagtgattt aggtcacaat
    35161 aagctgattg cacgtgccat taattacatt ggtggagatg ctaagctgac agaaacaatt
    35221 accaattata gccagcagct gctcaagcaa tttataggtg ttctaaccgg tattttgaca
    35281 tcggttacag cagttgcctc agccattatc aatgtggtta tcagctttgt cttttccctg
    35341 tatgtgcttg ctagcaagga agagctttgt cagcaggcaa ctaccttaat tgacacctat
    35401 actggtaaat acgcaaaggc cattcattat ttagtgggtt tgctgcatag tcgttttcgt
    35461 ggcttctttg tgagtcagac gcttgaagca atgattttag gctccttgac tgccattggc
    35521 atgtttatcc tgcaattacc ctttgcagga actattggag tcttggttgc ttttactgcc
    35581 ttgatccctg ttgttggtgc ttcaatcggt gctgcgatag gctttgtttt gattatgact
    35641 cagtcaatgt cgcaggcagt cgtctttatt gtctttcttg ttatactaca gcaaatcgag
    35701 gggaatttta tttatcccag agtggttggt gggtctatcg ggttaccagc tatgtgggtc
    35761 ttaatggcaa tcaccattgg tgctgctctc aaaggcattg ttggtatgat cgttgcagtg
    35821 ccattagcgg caacgcttta tcaagtggta aaggatcaca ttcataaaaa gcaggcctta
    35881 caaaatcgtc agtccagcta attaacagca tcagatcaag gaaaacgtct attacaagac
    35941 cgatttcttg gtcttttatg ctgtctgatt gactgcgtat ggccttattt ttatgctgtg
    36001 gtaatgaaaa aagccgtctt atttatcgaa tatcattagt ggaggtaata agatgtattc
    36061 catcaaaact gatcataaat taatgcctag agagcgtttg attcgactgg gtccagaaaa
    36121 gctaagcaat caagagcaac tagcgatcct acttaggaca ggtaacaagg aaaagcatgt
    36181 cttagagttg tctgcttatt tattgtcaag cttagatagt ctagctgact tgaagaaatt
    36241 ttctttacaa gaactacagc gcttatccgg gataggaaag gtcaaggcta ttgagattaa
    36301 ggccatgctg gagctggcag accgtattca gatagcggga caagcagtag cagatcctgt
    36361 cttatctagt gctcaggtgg ctgaaaagat gatgattgaa ttaggagaca agcagcagga
    36421 gcatttagtc gctatttatc tcgatagtca aaataaaatc attgaagaaa agacgatatt
    36481 tataggaacc gtcagaaaat caattgcaga gcctagagaa attctttatt atgcgtgtaa
    36541 aaatatggcg actagcctta ttgttgttca caatcatccc tcaggcctga ccaagccaag
    36601 cgcaaatgac tatcacttca cagaaaaaat aaaacgatca tgtgattatt taggacttat
    36661 ctgcctagat cacattatcg ttagtaagta tgactactat agctttcggg aaaaatcaga
    36721 tttattttga gttagaaact atggataaac caatcaaaga gccttaggtc ttcttctcta
    36781 atagcctgaa gcagctctgg gtgccactgg acaccgagaa agggaatatc aggattgcag
    36841 gagataacag cctcgatggt gccatcgtta ggatcccttg caatcactct taagtcctct
    36901 gcgacctgct ttaggctctg gtggtgaaat gaattaatca gcgctcttgg accatagata
    36961 gggtacaaag gtgaagtctt ttcgatcact atctcctgtg ataaacagtc agaggcagtc
    37021 ttttgccaat ggccctcaat gtgctggttt agactgccac ctagagcaac atttattaac
    37081 tgcataccgc gacaaatccc taaaattggt tttttctgcg ctagggcttc tttaatgatg
    37141 gctagctcaa agatgtcacg ctggggtgaa aaatcaccat caagtgcagc tcttttttca
    37201 tgataatatt taggatcaac atgctgacca ccaataagaa tgattttatc aaccattgcg
    37261 acataggatt tggcagccgc ctcatcccca atcggaagaa gtaagggtag gccaccagat
    37321 cttgtcacag cctcgatgaa gcttgttgga gcataggagc aaggcaggtt atctagagcc
    37381 ttggtccccc tttggttagc agttatccca ataattgttt tagacacgac cttctccatt
    37441 aatcaagatg attttggttc ataaagtata gcaaggtttg caactcgctg gtcaaatcaa
    37501 cagattggac gatcacacct tttggaacct gtaagtgaag tggagcaaag cttaaaatac
    37561 cgcgaatgcc agcttcaatc agttgatctg caacctcttg agcatagatg cttgggactg
    37621 ttagaatagc cgtttcaatg cctgaattat ccaggtgctc cttaatggta gaaatgccat
    37681 aaataggaat atcatcaggc gttttggtgc cgaccatagg attatcatca gtgtcaaatc
    37741 ccataacaat ctgcattttg tttcgatcgt ggaagcggta gtgaagaagt gcacgaccaa
    37801 tattgccgca gccaactaaa atcacatgcg ttgttgagtg atcatttagc aaatctgcaa
    37861 aaaaattcat taattttgtg acatcatagc caaatccacg tcggcctaat tcaccaaagt
    37921 aagaaaaatc acgtcgaaca gttgcagaat caattcccat agcatcagca atctgttttg
    37981 agcttgcctt ttcaacctga tcagcataaa agcgtttaaa aatacgataa tagagtgata
    38041 agcgttttgc agtcgctttt ggaatagatt tatcaataac cacttttgta gctccttcta
    38101 ttgttatttt aatgttatct atcaccattg tagcagatag attgtgaaat atgcaactat
    38161 ttgaccattc tttttgtgtt tttcgttata aaatgacttg acagcacaag cattggtatt
    38221 tttcaaaccc agtcacctcg agtataaaaa agcagacaat gaagcacttg ccctttaggt
    38281 cagctgcgat ggctgggctt gtcttgttaa aggcaaatgt actgtcattg tctgatattt
    38341 ctctgagatt agaagagctc ttgtgtgctt agcattcttt tttaatgaaa atatcacgct
    38401 caacaaggct atccattaaa aagtaaaact tgtcctgtag tatgctatgc tcttcagatt
    38461 taaaaatgtt caccagtctt agaccggatt ggtctgttat agctagctta aagccatcta
    38521 aatctttatt aatcgtaatt tttaaaggga agccctcacc cgaattaggg actttttcca
    38581 gtagtcgtgt taactgatag tgaccaatct tggtctgact aaaggttgtg tctcttaggg
    38641 tgtatttttt aatctttggg ctaatcctgt agctgtattt gcagtcttta agggcaattt
    38701 ctttttcaaa tgccatatga tcctcctaaa atatttttga gctgggttgc tagtgcgata
    38761 acgtcttttt gagtattttg ctctgaaaag ctaactcgaa tagcttctgt gagacgatgg
    38821 gactgcttgc cgaaataagc tgccaaaacg tgacttggct caacagcacc agctgtacaa
    38881 gcagagcctg acgacacagc aaagcctgct aaatcaagct gagtcagtaa tacatgattt
    38941 tggtaaccag gaaagccgat attaatgata tagggaagat gacactcatt atgattgagc
    39001 tgataagaaa taccttctaa ttcactaagc aagagctgtg atagctcttt agcatgctgg
    39061 taatgctgtg gcagccttga gacagcctca tctaatgctt gggtcatgcc gacgatatta
    39121 atcaggcttt cagtgccggc tctttgtttg ttttcttgat tgccgccatg taagaggggg
    39181 gccaacttta agcctttatt gtataaaaaa ccagtcccct ttggtccatg aaacttatgg
    39241 gcagaggcag agagcaaatc aatccccaaa tctgccggct gtattgggac cttgccaata
    39301 gcttggacag catcaacatg aaagacagcc tgatgctgct ttagcatgct accaacagcc
    39361 tgaataggca gcaaatctcc cgtttcgttg ttagcaaaca tcatgctgac taagattgta
    39421 tcctctctta aggcagcttg gagctgattt agatcaatga ttccattttt agcctcaagg
    39481 taggtcacct caaagccaaa tcgttcttcc agataggcca ttgtgcttaa cacggaatga
    39541 tgctcaatag cagttgtaat caagtgtttg cctttttcct gatgagctaa ggcatagccc
    39601 ttgatagcag tattgttact ttcagtacct cctgaggtaa agataatgtg gttttctgca
    39661 gctcctaggc agttggcaat agcttttcgg cactctctta attgtttgtt tgcctgccgc
    39721 ccataagcat gaatactaga tgggttacca aaatcatcag ccatagcttc agtcatcgcc
    39781 ttgatagcag cctgactaag cgatgttgta gcagcattat caaaataaat catgattagt
    39841 tagtgctttc aggtttgtaa gaaaacagtg gacttagtgg ttttctttcg tgaatgcgaa
    39901 tgatagcctc tgcaattaaa tcactggcac taagataggt tactgtttta gggatacgat
    39961 ttttagtctt gacagagtcc gtgacaatga tctctttgat tggagcagtc tctaaaatat
    40021 cagctgcacc tcctgcaaaa atcccatgac tagccactgc ataaatgtca gttgcgcctg
    40081 cacattctag gatcttagct gcctctgcaa aggtttttcc tgtgttgaga atgtcatcaa
    40141 tcaagatagc cttcttgcca gcaacatcac caatcacata gccttcttcg cgctcagcat
    40201 cgtcttgtgc ataatcgata atggcaattg gagagttaag atactctgct aagcttctag
    40261 cacgcttgat accagaattt ttagggctga caataaccgt atcaggtcct gagaggccca
    40321 gtggataata gtgctttgca aaaagaggca ctgtaaataa attatcaact ggaatgtcaa
    40381 aaaagccttg gacctgaacc gcatgcaaat caagggttac aacgcgatca atccctgctt
    40441 tggtcagcat gtttgcgacc agctttgctg taataggctc gcgagacttt gcaacacgat
    40501 cctgacgcga ataaccaaaa tatggcaaaa caatattgac tgtattagca cttgcacgct
    40561 tacaagcatc aatcatgatg agcagctccc ataggttatc gttgacagga aagcttgttg
    40621 attgaatgat ataaatatca tcaccacgaa ctgtttcttc aatgttaatc atgatctcac
    40681 catcagaaaa ttgacgagat gagacctttc caagcggaat accagcagcc ttagaaattt
    40741 tttcagcgat tgcgagattt gaagtgagtg agaacagctt gatttgcttg tcagcatatc
    40801 gttcagtcat gataaaatta gctccttaca ttacattaac gatagaataa caggttaaca
    40861 gttattcaag attacaaata gacagtacta ttttaacaaa aaaacagaaa aatttcagtc
    40921 tttctgttga ttttctgtcc tctcctagga ttttttaagg gtcttgctaa agcgagcgac
    40981 cttgcttttg gaatatttaa aggtgatctg atgctgggct aaaaagtggt caaaatcaac
    41041 ctttcctctt acaggatcag tcacctctag ctcaagctca tagtctttga taccagcata
    41101 ttgattataa tccagcgcta gcttgccaat aggagtatct gcctctcgac gaatggtagt
    41161 caggtttccg aaggttttta tagcagatag gtcaacgtca agagtgctga taatatcaag
    41221 gatagctgat tttggtagct gtcctgtctg aatgatagct tttgcttggg tgtcatcaag
    41281 ctctaaattg tactcgcgat taccaacctt ttcagggact tttaaggtta attcagcagg
    41341 agcagcaaca aaggtgcgaa tgcgaagtga cattttatga gccttgagat caaaatgatc
    41401 agtatcaatg taataatttg tctgggtaac tggtgggaca tgagtcattt gagagaggag
    41461 gcgattatat tcgtcctttg tcagtaaggt cttgtattcg atttctaggt tagtcatgcg
    41521 aacgttcctt ttaactatat tttatgctat aataaattgt tatcttaatt ttatattaat
    41581 atccgaggtt tgacaagaaa ggagagaaag gatggcttta gattgggaag aatttttgga
    41641 tccttatata caaacggttg gcgaattgaa aattaagctg cgcggtatcc gaaagcagtt
    41701 tcgcaagcaa aaccgttatt ctcctattga gtttgtgact ggacgtgtca agtcggttga
    41761 gagcatcaag gaaaaaatgg ccttgcgtgg tgtcttggaa gaaaatatcg ctcaagatat
    41821 tcaagacatc gctgggctta ggattatggt gcagtttgtg gacgatattg aggacgtttt
    41881 gtccttgctt agacaaagac aggacatgac aattgtttat gagcgagact acattagaaa
    41941 catgaaatct agtggttatc gctcgtatca tgttgtcgtt gagtatcctg ttgataccat
    42001 tgagggtcaa aaaaaagtat tagcagaaat tcaaatccgt actttagcaa tgaatttttg
    42061 ggcaaccatt gagcattcct tgaactacaa gtacggtggt gattttccag aagaaataaa
    42121 aaaacgatta gaggttacag caaaaattgc tttggagctt gatgaagaaa tgcgaaaaat
    42181 tcgtgaagac attcgtgaag cacaattgtt atttgatcct gtaacacgtc atttgagtga
    42241 tggtgtagga aatagtgatg acacagatga attatacaga taaagtaaag cgcgttgcta
    42301 tcattgcaaa cggcaaatat cagagtaagc gccttgcctc aaagcttttt ggcgtcttta
    42361 aggacgatcc gagtttttac ctatccaaaa aaaatccgga tattgtgatt tcaattggcg
    42421 gagatggcat gcttctatca gcctttcata tgtacgaaaa agaattagac agggtgcgat
    42481 ttgtaggcat tcacactgga caccttggtt tttacactga ttatcgtgat tttgaggttg
    42541 atcaattgat agccaatctt agaagagaca ccggtgagca aatttcttac cctattttaa
    42601 aggtagttat tacgcttgat gacggtcgcc tgtttaaggc tagggctctc aatgaagcaa
    42661 ctattaagcg tatcgagaaa acgatggttg cagatattat cattaacaat gtcaagtttg
    42721 aaagctttcg tggtgatggc atctctgtat ccacaccaac tggaagcaca gcctataaca
    42781 aatccttagg tggagctgta ttgcacccaa cgattgaggc ccttcagcta acagaaatct
    42841 cgagcctgaa caatcgtgta tttagaacct tggggtcctc agtgattatt cctaaaaaag
    42901 ataaaattga gcttgttcca aaaagactag gcgtttatac tgtctctgtt gacaataaaa
    42961 cctaccactt aaaaaatgtg gttaaggtgg aatattttat cggcaatgaa aagattcatt
    43021 ttgtgtcctc acctagccac accagctttt gggaaagggt taaggacgct tttattgggg
    43081 atagtgaatc atgaggtttg aatttgttgc aactaaaaaa acaaaggtaa agaccctttt
    43141 aaaagagcac gatgtgtcaa agggattgct cgctaagatt aaatacaagg gtggcaatat
    43201 atgggtaaat ggcgttgcgc aaaatgccat ttatttattg gatattggtg atgtggtggc
    43261 tattgatatt ccaaatgagg agtcctttga gcaattgaca gcgatttcgc atgaccttga
    43321 tattgtgtat gaggacgaac attttctcat tctcaacaag cctgctggct acgctagcat
    43381 tccaagtgct atccattcta atactatagc taattttatc aaggcttatt atatcaagca
    43441 ggactatccc aataaacagg ttcatattgt gacgcgctta gatcgggata ccagtggctt
    43501 aatgctcttt gccaagcatg gctatgccca tgccagatta gataagcagc tacagcaaag
    43561 agctatcaat aaacgctatt atgctcttgt ttgtggtcag gagaggcttc cagatcaagg
    43621 tgagattata gctcctattg gccgtacgga cgacagcatt atcacaagaa ctgtcacgcc
    43681 aaagggaaag tatgctaaga caagctacaa ggtcattgcc cgctatcctg aaaatgtctc
    43741 tctagtggat attacgctgc acactggtcg gacccatcaa attagggtac attttgctca
    43801 tcttggtttt ccacttttgg gagatgatct gtatggtggt cgattggacc ttggcatgac
    43861 tagacaggcg ctgcattgtc accatcttag ctttacgcac ccatttacag aaagtagaag
    43921 cgatcataca atatgcttga cagatgactt tgagagcgtt atcatagatt tacagaaaaa
    43981 agatagaggt tagttaatga gtattcgtaa tttatttggt ggtttaaggg aaaaaattgt
    44041 cggcaaaaac atgaagattg ttttccctga gggaaatgat gagcgtgttg tacgtgcagc
    44101 agcacgtcta aagtttgaag gtcttgttga gccaattatt cttggtcagg cagatgatat
    44161 tcgcagcctg ctaacacagc taggctttgc tgagcagcac tatacaatca ttaacccaaa
    44221 tgattatgct gattttgaga aaatgaaagc agcctttgta gagcttcgta aggtcaaggc
    44281 aacgcttgaa gatgctgata gactgcttag agatgtcaat tactttggtg ttatgctggt
    44341 taagctaggc ttagcagatg gcatggtttc aggggctatt cattcaacag ctgatacggt
    44401 gcgtccggcg cttcagatta tcaagacaaa gccaggcatt tctagaacat caggtgtctt
    44461 tttgatgaat cgcgaaaata cagagcagcg tttagtgttt gctgattgtg ccattaatat
    44521 tgacccaact gctcaggagc tcgcagaaat tgcggtaaac acagcagata ctgcgaaaat
    44581 ttttgatatt gatcctaagg ttgccatgct tagcttttca acaatgggct ctgctaaagc
    44641 cccacaggtt gaaaaggttc aagaggccgt ccgtattgct aaggaattga ggccagagct
    44701 tgctttagac ggtgagcttc aatttgacgc agcctttgta ccaagtacag cagcgatcaa
    44761 agcccctgat tcatcagtgg caggccatgc gaatgttttt gtcttcccag atttacagtc
    44821 tggaaatatt ggctataaga ttgctcagcg cttaggcatg tttgatgcta tcggaccaat
    44881 cctgcaagga ttgaacaagc ctgttaatga tttatcacgt ggctctagtg cagaggatat
    44941 ttacaagcta gctattatta cagcagcgca agcgcttgaa aatgagtcta tcaattaact
    45001 gctaatagcc attaagttca caaggcttag ctatagtaga tgttgcttaa aacgagttgg
    45061 ataagccagc tcgttttttc agaaagtgag gaaggaaatg acaaagattg cattagtaac
    45121 aggcgcctct gctggctttg gtaaagccat tgcagagcag ttaatagccc aaaacatcaa
    45181 ggtgatcgga gcagcccgcc gcatagaaaa gctaagagag ctagaaggta tttttggttc
    45241 tgagaggttt tatccgcttc aaatggacgt ttcagaacca actgccattg ataaagcact
    45301 tgcagaatta cctaaagaat ggcaggccat tgatatttta gttaataatg caggactagc
    45361 cttaggactt gataaggcct atgaggctga tgtcgccaac tggctaacca tgattaatac
    45421 taatattatt gggcttatct atttaacacg tcaggtatta ccgcaaatgg taagcagcaa
    45481 caatggcatg atcatcaata tcggctcaac tgctggcact attccctatc cgggagctaa
    45541 tgtttatggg gcttcaaaag cctttgttaa gcagttttcg cttaatttaa gggcagattt
    45601 agcaggaaca aatatcaggg tgaccaatat tgagcctggc ctttgtgagg gaacagagtt
    45661 ttctcatgtt cgctttaagg gtgaccatga gcgtgttaaa gcactttatg caggtgcaca
    45721 tgctattcag ccaagggata tcgcaaatac tgtctcatgg attattgatc agccagagca
    45781 tgttaacatt aaccgcgtgg aaatgatgcc tgtctcacaa agctatggtt ctcagcctgt
    45841 tagccgtcat gactaagaat tacaagagca gatgtaaaag gattgtcgaa gtgcaaccca
    45901 aaaagactta aagcctagct gttttatagc ctggctttaa gtctttttct ctaatttttc
    45961 ttagaaatga tccgaaagag aaggtccaga tgtgacatct gaccacccaa caatggcctg
    46021 ccctgtttct tccaaatagt gctgcagcat aggcttgaag tccaaaatca tgtcatagac
    46081 cccaacaaat tgcttggtat catcgtacaa ggcttgatat tgctgcatat aaatatgatc
    46141 ctgtgaagca gtcggaataa gatacagctt actgccagtt gccgccttgt gcaaatcagt
    46201 caagatccaa tcctcaatga catcatgctt atcagaagca aaaaaattgc cattaaagcg
    46261 atgattatca aagatgatct gcccctgatg atcagcaatt ctagcctgaa ggggaagata
    46321 ggttaaaaaa tgtggggcta aggcttggta aaattgcatg aggtatttag caagtcttaa
    46381 agtttgctga ctatcagtaa aggtatgatc actaacggta aatccttgct ctttgtctgc
    46441 ctgattaaaa taaagtacag gtagtgaggc ttcaaggttc tgaaaggtaa aaatggcctg
    46501 agcctttttg agctgctcag tagtcagctg acggacaata gtgatatgaa acagatagct
    46561 aaactcttgt gataaggtgg taaaaaaagt cttttgcaga ttattcttat catcaaccag
    46621 tgctaaggta taaatcgttt tagtcataag gctatcatag ctttattttg tttaaatagc
    46681 aatgaaacag ccttttagtc tacagactta gttgatagct taataaaaga aagcaatatg
    46741 aaaaaatgat taaagcaaac tagttgactt gttagtttaa actttttata ataaatcaaa
    46801 tgagaagata atatgaggct tagcctaagc tgctgagctt atctgataat cattcttctt
    46861 agcactgaga taaccccctt tatcgattaa ttggagaatc tatgatacgt tttaataatg
    46921 tttccaaaac ctttggtcac accaaggtgc tgcaggagca aagttttcaa atacagaatc
    46981 gcgaattttt tgtgctggtc ggtccaagcg gctctggcaa aacaaagctc ttaaaaatga
    47041 tcaattgcct tactgaacca agctctggcg aaattctatt aaacggaagg ccacaaaaag
    47101 agctagattt gcgagatatg cgcttatcta ttggctatgt tcttcagcaa attgccctgt
    47161 ttccaaacct tacagttgct gaaaatatcg ctattattcc agagatgaag aagtggtcag
    47221 acaaagagat tagaactaag acagaggaat tgttagataa ggttggattg cctgcaaggg
    47281 attatctaaa tcgctatccc agtgatttat ccggtggaga gcagcagagg attggtattg
    47341 ttcgtgccat catttctcac cccaaggtgc tgttaatgga cgagccgttt tcagccttgg
    47401 atcctatttc acgcaagtaa ttacaggact tgatgttaag tcttcacaag gagtttgata
    47461 tgacaattgt ctttgttact catgatattg atgaggctat caagcttgga gatcgtgtgg
    47521 ctgttttaaa tgaagggcaa attgttcaac tggatcgacc agatgcgatc atagctgcgc
    47581 ctgctaatga ttttgtagca agtctatttg gaggtcgtga ttatgcctag tttactgatg
    47641 accttttggg atcgttttgg tgattgggca agggcattag gagagcactt gcagatttct
    47701 cttctttctt tgctggctgc cttgctgata ggcattccgc ttgcagctct gttgagtaaa
    47761 agtaagcgct ggtcaaatat catcttgcag ctgacaggtg tttttcaaac cattccttcc
    47821 ctagccttgt tgggactatt tatccctcta atgggaatcg gaactgctcc agctgtaaca
    47881 gctttggtta tttatgccat atttcctatt ttacaaaata cgattactgg cttaaatgct
    47941 attgatccaa gtcttgtaga ggccggaaca gcctttggaa tgaccaagtg ggagcgactg
    48001 aaaatatttg aaattcctat tgctatgcca gttattatgt caggtgttcg gacctcagca
    48061 gtgatgatta ttggaacagc caccctagct tctttgatcg gagctggcgg cttagggacc
    48121 tttatcctat taggaattga ccgtaataat gctcagctga ttgtgattgg tgctgtgtcg
    48181 tcagccttgc ttgcgatagt gtttaacagt cttttgtgat accttgagaa ggcctcactg
    48241 aggcgtattg cgataagctt tgctgcgacc ttattactgc tcttaatttc ctatactcca
    48301 atgtttgtca agcggtttgt taatcagtca aatactctgg tgattgctgg caagctagga
    48361 gtagagccgg atattttgat caatatctat aaagagctga ttgaagacca gtccaagctt
    48421 aaggttgaat tgaaacctaa ttttggcaag acaagctttt tatacgaggc gattaaatca
    48481 ggagatattg atatttatcc agaatttaca ggaaccatca cctctagcct attaaagaaa
    48541 aagcctaagc tttctaatga ccctaatcag gtttacttag ctgctaagga ggggattgct
    48601 gagcaggatc agttgacgct tttaaagccc tttgcctatc aaaataccta tgcagtggcg
    48661 atgcctgaaa aaatagctga cgaatttaac attcaaagta tttcagatgt gaagaaatat
    48721 gaaaaacagc taaaggctgg ttttacacta gaatttaagg atagagagga cggctataag
    48781 ggcatacagg ataagtatga tctacattta tcagttgcaa cgatggagcc agctcttagg
    48841 taccaagcca ttcagtcagg aaacattcag ctgacagacg cttattcaac tgatgctgag
    48901 atcgtgaaat atcagcttcg agtcttaaag gacgataagc agctctttcc accttatcaa
    48961 ggagcgccat tgatgaaggc ttccttacta agaaagcacc ctcatctcaa aacgattctc
    49021 aatcagttat caggaaagat tactgaagag gagatgcaag caatgaacta tgaggtgtcc
    49081 gtaaagggca gagcagctag ccttgtggca catgactacc ttgtaaaggc cggtcttatt
    49141 gcaagaacca aataagcagg catgctagtc ttattctgga ctggcatgct ttatttatgt
    49201 gatttttagt ctgtctggct ctgcaaggtg tgtgccaaat aaccgctcgt ttgatgtgtg
    49261 gttattgatt tagtagctaa ggattggaat cttaaaataa aatccgaacg tttgtctaaa
    49321 aaaagcttta aaaattgaca aaacataaac gaaaggataa aataaattaa ggaaaggtaa
    49381 cattttacct agcgatgcct cggacaagct tgaggtcata ggaaggtcat tttatataga
    49441 agcttatgtc agctgcagat cagggaagtc cttgctggat tagtagctga atgttgaaaa
    49501 aggagagaaa tgatgtttaa tgacatgcct gtatttgatt atgaggatat tcaattaatt
    49561 cctaacaaat gtatcatcaa tagtcgttca gaagcagata cgagtgtaag acttggtaat
    49621 tataccttta agctacctgt tattcccgcc aacatgcaaa ccattattga cgaaacaatt
    49681 gcagagcagt tggcaagaga tggttatttc tatattatgc accgctttga tgaggagggg
    49741 cgcaagccct ttatccagcg tatgcatgag caacagctca tcgcctctat ttcggttggt
    49801 gtaaaggatt atgaatacga tttcgtctct tctttgaagg aggacgcacc tgagtttatc
    49861 acgattgata ttgctcatgg ccatgctgat agtgtgatca aaatgattaa gcatattaag
    49921 gctgagctgc ctgagacctt tgttatagct ggaaatgtcg gaacaccaga ggctgttcga
    49981 gagctcgaaa atgctggtgc tgacgcaaca aaggtcggga ttgggcctgg taaggtttgt
    50041 atcacaaagg ttaagacagg ctttggaaca ggggggtggc aattagctgc tgtacgttgg
    50101 tgtgctaagg ctgctcgtaa gccgattatt gctgatggcg gtattcgtac tcatggtgat
    50161 attgccaagt cgattcgatt tggggcaaca atggtgatga tcggttcact ctttgcaggt
    50221 catattgaaa gcccaggcaa gatggtagaa atcgacggac agtccttcaa ggaatattat
    50281 ggctctgcct ctgaatatca aaaaggggag cataaaaatg tcgaaggcaa gaagattttg
    50341 cttccaacca agggtcatct agctgatact ttaaccgaaa tgaagcagga tttacagtca
    50401 tcaatctcat atgctggagg cagagatttg gagagcctgc gtcgtgtgaa ttatgttatc
    50461 gtgaaaaatt ctatttggaa tggtgactct atttaaagcc ttggctaaag acctagtcta
    50521 aataaggata agcaagctga ttgatgctga gaataagcac agcgtgtcta taggacgcct
    50581 gaatgtctag tagccagtaa agcttttagg cttgctgatt ggataggtca ttgtgcctat
    50641 gtgcagcagg gctctaggga cttagataaa aaggagacat gatgaggtta ctggaggagc
    50701 gtatcctagc tgatggaact gttttaggtg agacgatttt gaaggtggat caatttttaa
    50761 cacatcaggt tgactatcgc ttgatgaagg aaatcggtag agtatttgct gatcaatatg
    50821 ctgatttggg cattaccaag gtggtcacca ttgaagcctc tggtatcgca ccagcagttt
    50881 ataccgcaga agctcttgag gttccgatga tttttgccaa aaagcacaaa aatatcacga
    50941 tgacagaggg aattttaaca gcagaggttt attcctttac caaacaagtg acaagtactg
    51001 tttctattgc aggaggactg ctatcaaaag aagatagggt tttgattatt gatgactttt
    51061 tggctaatgg tcaagcggca aaaggcttga ttgatatcat tcatcaagca ggggccaaag
    51121 ctgttggcat aggcattgtc attgaaaaat cttttcaggc tggacggcaa ttgcttgagg
    51181 atttgggagt agaggtcact tcattggctc gtattaagca ttttgacaat ggaatagtaa
    51241 gctttttgga ggctgatgcc tgatgactgc ttcttatctc tcagcattaa gctttttact
    51301 tgtatagcta taccagcttt atttcagtag ctattggctg gtgataaggg atattggtat
    51361 ggcggtgcat tacggcgagc cgtgggcagt tgcccttgcg gctttacgat ttagtataga
    51421 ctatcaagaa ttgactgctt cctttttatc gagatgaatc attagacaga caatcatgat
    51481 ttggcgtgaa ggctgctttc agtaaacatt acatcatcaa aaatcagcta ggtattcact
    51541 tagctgattt ttagtgctta taatgtagcc gaaaggctcc ctttaacccg tctgagatag
    51601 taacctgacc atctttggta atgataatgc cttccacctc aggcagctta tttagctgac
    51661 ttaggacaaa ggaatgctct aagccaaaaa gacgactact ccatagctca ccatcaagtg
    51721 agaattggct gacaatggtt aggctagcca tattggtctt gataggatag ccgttgtgag
    51781 gatcaagaag gtgatgataa gttttgtctt tgatttgtaa ttgtctctcg ccgattcctg
    51841 aggttactac agatttattg ttaaccttaa tcacgccgac atgctgtcct cttttttgat
    51901 tggtctgctg gatcccaacg taaaacaagc cattatgtcg ttgcttgttg gtgccatgca
    51961 caaggacatt tccacctaga ttgataagag cagcagtgat accgtcttta ataagaaatg
    52021 ccatgagctt atcagcaata tagccctttg ctagggcacc taagtcgata gacatgccct
    52081 tttctttcaa aaaaatactt ccaaggcttt gatctaa
//
LOCUS       DARYUW010000006        50719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYUW010000006 DARYUW010000000
VERSION     DARYUW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            175..963
                     /locus_tag="TVW11_000309"
     CDS             175..963
                     /locus_tag="TVW11_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1364449.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TVW11_000310"
     CDS             972..2141
                     /locus_tag="TVW11_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1364450.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TVW11_000311"
     CDS             2144..2347
                     /locus_tag="TVW11_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364451.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TVW11_000312"
     CDS             2479..3912
                     /locus_tag="TVW11_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1364452.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5111)
                     /locus_tag="TVW11_000313"
                     /pseudo
     CDS             complement(3942..5111)
                     /locus_tag="TVW11_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5167..5808
                     /locus_tag="TVW11_000314"
     CDS             5167..5808
                     /locus_tag="TVW11_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1364453.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5929..6855
                     /gene="cysK"
                     /locus_tag="TVW11_000315"
     CDS             5929..6855
                     /gene="cysK"
                     /locus_tag="TVW11_000315"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1364454.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7242..7604)
                     /locus_tag="TVW11_000316"
     CDS             complement(7242..7604)
                     /locus_tag="TVW11_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1364455.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7604..9004)
                     /locus_tag="TVW11_000317"
     CDS             complement(7604..9004)
                     /locus_tag="TVW11_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1364456.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9037..9678)
                     /locus_tag="TVW11_000318"
     CDS             complement(9037..9678)
                     /locus_tag="TVW11_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1364457.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9671..10675)
                     /locus_tag="TVW11_000319"
     CDS             complement(9671..10675)
                     /locus_tag="TVW11_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1364458.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIIQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10672..11364)
                     /locus_tag="TVW11_000320"
     CDS             complement(10672..11364)
                     /locus_tag="TVW11_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1364459.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYVIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11497..13392)
                     /gene="pknB"
                     /locus_tag="TVW11_000321"
     CDS             complement(11497..13392)
                     /gene="pknB"
                     /locus_tag="TVW11_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1364460.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13389..14129)
                     /locus_tag="TVW11_000322"
     CDS             complement(13389..14129)
                     /locus_tag="TVW11_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1364461.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14167..15489)
                     /gene="rsmB"
                     /locus_tag="TVW11_000323"
     CDS             complement(14167..15489)
                     /gene="rsmB"
                     /locus_tag="TVW11_000323"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1364462.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15479..16414)
                     /locus_tag="TVW11_000324"
     CDS             complement(15479..16414)
                     /locus_tag="TVW11_000324"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1364463.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16481..18865)
                     /locus_tag="TVW11_000325"
     CDS             complement(16481..18865)
                     /locus_tag="TVW11_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1364464.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18929..19246)
                     /locus_tag="TVW11_000326"
     CDS             complement(18929..19246)
                     /locus_tag="TVW11_000326"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1364465.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARFEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19271..19897)
                     /gene="gmk"
                     /locus_tag="TVW11_000327"
     CDS             complement(19271..19897)
                     /gene="gmk"
                     /locus_tag="TVW11_000327"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1364466.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20059..21669)
                     /locus_tag="TVW11_000328"
     CDS             complement(20059..21669)
                     /locus_tag="TVW11_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1364467.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21826..22311
                     /locus_tag="TVW11_000329"
     CDS             21826..22311
                     /locus_tag="TVW11_000329"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1364468.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22456..23907)
                     /locus_tag="TVW11_000330"
     CDS             complement(22456..23907)
                     /locus_tag="TVW11_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364469.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23921..25075)
                     /locus_tag="TVW11_000331"
     CDS             complement(23921..25075)
                     /locus_tag="TVW11_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1364470.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25139..25507)
                     /gene="rnpB"
                     /locus_tag="TVW11_000332"
     ncRNA           complement(25139..25507)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TVW11_000332"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25520..25843)
                     /gene="gpsB"
                     /locus_tag="TVW11_000333"
     CDS             complement(25520..25843)
                     /gene="gpsB"
                     /locus_tag="TVW11_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1364471.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25965..26480)
                     /locus_tag="TVW11_000334"
     CDS             complement(25965..26480)
                     /locus_tag="TVW11_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1364472.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26556..27164
                     /gene="recU"
                     /locus_tag="TVW11_000335"
     CDS             26556..27164
                     /gene="recU"
                     /locus_tag="TVW11_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1364473.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27151..29316
                     /locus_tag="TVW11_000336"
     CDS             27151..29316
                     /locus_tag="TVW11_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1364474.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29359..30693)
                     /gene="pepC"
                     /locus_tag="TVW11_000337"
     CDS             complement(29359..30693)
                     /gene="pepC"
                     /locus_tag="TVW11_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1364475.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31382..32206)
                     /gene="nadE"
                     /locus_tag="TVW11_000338"
     CDS             complement(31382..32206)
                     /gene="nadE"
                     /locus_tag="TVW11_000338"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1364476.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32203..33663)
                     /locus_tag="TVW11_000339"
     CDS             complement(32203..33663)
                     /locus_tag="TVW11_000339"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1364477.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33939..35333)
                     /locus_tag="TVW11_000340"
     CDS             complement(33939..35333)
                     /locus_tag="TVW11_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1364478.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35453..36370)
                     /gene="trxB"
                     /locus_tag="TVW11_000341"
     CDS             complement(35453..36370)
                     /gene="trxB"
                     /locus_tag="TVW11_000341"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1364479.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36430..36657)
                     /locus_tag="TVW11_000342"
     CDS             complement(36430..36657)
                     /locus_tag="TVW11_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1364480.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36767..37510)
                     /locus_tag="TVW11_000343"
     CDS             complement(36767..37510)
                     /locus_tag="TVW11_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1364481.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37510..38313)
                     /locus_tag="TVW11_000344"
     CDS             complement(37510..38313)
                     /locus_tag="TVW11_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1364482.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38690..39517)
                     /locus_tag="TVW11_000345"
     CDS             complement(38690..39517)
                     /locus_tag="TVW11_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1364483.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40025..40480
                     /locus_tag="TVW11_000346"
     CDS             40025..40480
                     /locus_tag="TVW11_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364484.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41121..42464)
                     /locus_tag="TVW11_000347"
     CDS             complement(41121..42464)
                     /locus_tag="TVW11_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1364485.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42547..43554)
                     /locus_tag="TVW11_000348"
     CDS             complement(42547..43554)
                     /locus_tag="TVW11_000348"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1364486.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43556..45811)
                     /locus_tag="TVW11_000349"
     CDS             complement(43556..45811)
                     /locus_tag="TVW11_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1364487.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45815..46138)
                     /gene="ftsL"
                     /locus_tag="TVW11_000350"
     CDS             complement(45815..46138)
                     /gene="ftsL"
                     /locus_tag="TVW11_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1364488.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46142..47092)
                     /gene="rsmH"
                     /locus_tag="TVW11_000351"
     CDS             complement(46142..47092)
                     /gene="rsmH"
                     /locus_tag="TVW11_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1364489.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47195..47611)
                     /locus_tag="TVW11_000352"
     CDS             complement(47195..47611)
                     /locus_tag="TVW11_000352"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364490.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47631..48878)
                     /locus_tag="TVW11_000353"
     CDS             complement(47631..48878)
                     /locus_tag="TVW11_000353"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1364491.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48878..49696)
                     /gene="proB"
                     /locus_tag="TVW11_000354"
     CDS             complement(48878..49696)
                     /gene="proB"
                     /locus_tag="TVW11_000354"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1364492.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50297..>50719
                     /locus_tag="TVW11_000355"
     CDS             50297..>50719
                     /locus_tag="TVW11_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364493.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14990 a        11589 c         9688 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctt gaccttgcgc
     4381 tctaaatctc ttgtagaggt tgctgttagg tatactgtca ctgcatctgc ttttgcagcc
     4441 tgatgagcag catggtttaa ttgacgatta ttgacaaagg ggaaggcatc tacttcgtca
     4501 ataatgagca gatcaaaagc atggtaaaag gtcatcaatt gatgtgttgt ggcaacgata
     4561 atggggcttc tatgataaac ctctgactca gcatgcataa ggcagacttg acaggaaaag
     4621 tcccgcgata gtcgtttttc aagctctatg caaacatcaa ctcgtggact agcaatgcag
     4681 acccagccac ccttattaac aactgctgca atagcttcat acatcatctc tgttttgcca
     4741 gcaccagtaa ccgcatgaac taaggtgtct tgcttgagct taacatggtt agtaagctga
     4801 tgagagatag ctgcctgata tgtcgtgagc tgtccttgcc acctcagata atgtcccttt
     4861 ggaaaagaag ccggtggaaa atagagcaag gggcgatcag attggtttcg accaaaaaca
     4921 agacaggctc tacagtagta agcaccgcta ggcagctgat gagccttctc aattaaactg
     4981 ctacagcgtt ggcagtataa cgttcccttt ttagtgatca tgctttgtaa gctgcaagcc
     5041 caggcagaaa cagcctttgg gcattgcctt tcgggtaaaa gacgtccata gtaattttcg
     5101 atattctcca taccttatta tccgaattat tttgctaaat atcagcattt tttgtaaaat
     5161 tttcttatgg aagattataa aactattatg actgatgggc tttttgagga aagcatcaaa
     5221 aaatctcgct ttatttgcca aatcaaacgc gtctacacag aagaggaggc cagagccttt
     5281 attgctgaca tcaaaaaaaa gcactataag gccaatcatt cctgctctgc tatgattatc
     5341 ggagacaaag gacaaaccaa gcggtcaagc gatgatggtg agccatctgg tactgctggt
     5401 attcccatgc tatctgtctt agaaaggcag gaattaacca atcttgtagc tgttgtgaca
     5461 cgctattttg gaggtgttaa attaggagct ggagggctca ttcgcgctta ctccggcgta
     5521 actgcggcag ctattcaggc cttaaaggtc gttgaggtaa aaaaacaaac tggactagca
     5581 atcagcctca cctaccctca ataccaaatc tatcctaatt ttctggagca agaagcattg
     5641 attgaaatga ataccgaatt ttctgatgtc gtcagaacag ctatttactt tgatcctgag
     5701 cgcttggaga gtatttctaa ggcattgatt gagcattatc atggcaaggt ttcctttgaa
     5761 gagatcgaat cgcaaaggat tgaggtccct gttttgcctg ccaattagca tgaacagtga
     5821 tagcgtctct ttatcactac gatagtaaat ggctatttta ctttgtcgat tattagctat
     5881 atacttttat ataagcatgt attgatacaa ggataaaaag gaggacctat gtcaaagcta
     5941 tatcacaaca ttacagagtt ggttgggaaa acccctatta ttaaattgag aaacaccagt
     6001 ccagaggagg ctgccgatat ttatgtcaag ctagaagctt ttaatccagg ctcttcagtt
     6061 aaggatcgca tagcacttgc aatgattgaa gctgctgaga aagcaggcat gatcaagcca
     6121 ggtgatacaa tcgttgagcc aaccagtggc aatacaggga ttggcttatc ctgggttggg
     6181 gctgcaaaag gctaccgagt gctcattgta atgcctgaga caatgagtat tgaaagacgt
     6241 caaatcattc aagcttacgg agcagagctc gttttaaccc caggtagtga tgggatgaaa
     6301 ggtgcgattg ctaaagcaga agagattgcc agagagaccg gtgcttggat gccctcgcaa
     6361 tttgacaatc ctgcaaatcc caaggttcat gaagagacaa cagggcaaga aattatcgcg
     6421 gtttttggag aaaaaggact tgatgccttt gtttctggtg tgggaactgg tggcactatt
     6481 tctggcgttg cgcatgcctt aaaggctgtt aatcctgata tttctatcta tgctgtggaa
     6541 gcagatgaat ctgccgtctt atctggtgaa gagtcttctc cgcacaagat tcaagggatt
     6601 tcagctggct ttatcccaaa taccttagat acaaaggcct atgaccacat cattcgagta
     6661 gcgtcagagg ctgcccttgc cactgctcgg tcaatcgggg ctaaggaggg ctttcttgta
     6721 ggcatttctt ctggagccgc tgtttatgct gctatccaag ctgctaagga gcttggaaaa
     6781 ggtaaaaagg tcttagctat attaccagat aatggtgagc ggtacctgtc tactgccctt
     6841 tatcagtttg attagaataa tcatataagc accagcccta gcagctagaa taagctttca
     6901 agcataaatc atcgctctta cttagtcacc attaaaggcc agtcagctag catatggaaa
     6961 aatgcttact ttgattcctt tttaacaata aacatagcat accacgccta agcgccccag
     7021 agcttctagc ttcttggaaa taggctttcc tagccgcttt caccacagta aaaaagactc
     7081 aagctagtag gctaagatgt tcaaagagga ctagcaatca caattggctt tttttgaaga
     7141 tagctttgag ataagtaagg tgactggtcc agagctgata gcaaaaaacc gaggaacagt
     7201 tcatatagct gtttctcggt tttttatgtt tccaagtctg tttacgattt ttcctgctta
     7261 aagtggtcta agccttcctc aatccaattg ggtaagctgg cttcaagagg cttaaagcca
     7321 atcttataac ggctgtttga aaagcgatga tgacttgaca catgatgctt ttcctcctcc
     7381 aaagttctca aggacaggct gaccttatga ctgtattcgt catagtcaat gacctgaact
     7441 aaaaccgcct caccaagtct taggatctga tgaatattat caataaatcc cgtcttaatt
     7501 tctgaaatat gaatgagacc tgttgtccca ttttcaaggg caacaaaggc tccatagggt
     7561 ttgattcctg taatggtccc atgcagctta tcgccaattt tcatcaatca aatacctcga
     7621 tggcctcaat gacaacgtcc tcttttggct tgtcttgtgc ccctgtttcg acagcagcaa
     7681 tgttatccaa gacctgataa gaggcttcat cagccaactg accaaatact gtatggcgac
     7741 gatccaggta aggagtcccc ccatgttcag cgtaggctgc tgcaatgtcc tttggccagc
     7801 caccacgctc taattccttt tgagaataag gaaggcttgt attttggacg ataaagaatt
     7861 ggctgccgtt tgtatttggt cctgcattag ccatcgaaag ggctccgcga aggttgtaca
     7921 attcctctga aaactcatcc tcaaagcttt gaccatagat ggattgccca cccattccag
     7981 tgccagtcgg atctccacct tgaatcataa aatctgcaat aatacgatgg aaaataacac
     8041 cattatagta gccttcctta gctagaccta agaagttagc aactgttttt ggagcatgct
     8101 ctggaaataa agccaatgtc agctcaccat gatttgtttt catcaccact cttggtcctt
     8161 catggccagc caaatctagc tgcggaaaat gtaattcttt gtcaatcaaa cctaattcct
     8221 ccaaggcata taaaatgccg ttttcttcaa ctgttttagt aataaaatct gctttttctt
     8281 gtaattgtgg gtgagaaacc cccatagcaa tgctgatgcc agcataatca aatagctcta
     8341 aatcattgag ctcatcacca aagaccagga tattttcagg ccttaagccc aaatgctcaa
     8401 caacctttga tacacctaga gccttagagg tgccctttag gaccacatca gaggagtgat
     8461 catgccacct tactaggcga agctgctcag ccaattcaac aggtaattgc aggtcatctc
     8521 ccttgtcctc aaaggtccac atttggtaga catcatggtg ctcattgtaa tccgggcata
     8581 cctctagtgt ggagtaaacc ttatcaatag catcactaat catctcgtta cgagctgata
     8641 agacagcctc gtgacgtcct gccatgccat aatcaatgcc gactgcattg gcccattttt
     8701 tataggctac aacagtgtct gctgggatag gtgcctgaaa gataatgttt ttttgattgt
     8761 ccttcacata agcaccattt agcttaacac aataatctgc ctgtaaatcc tgaacctcct
     8821 tgggcacacc atatctggcg cgacccgaag caattcctgt taggatccct tttttcttga
     8881 gctctttgaa aaccctctgg atagactctg gcatatagcc tgtgttcttt acgcgcaggg
     8941 tatcatctat gtcaaagaaa accatcttga ttttcttggc cttatacttt agttttgcgt
     9001 ccatactttc ctccatgcaa tagtactatt atagcattaa tgatcatctt gaggcactaa
     9061 atgatgtcgg aaagcgtata caacagcctg agtacgatca tcaacctgca atttggctaa
     9121 aatatttgac acgtgagtct taactgtctt caaggaaata aaaagctcat cagcaatggt
     9181 ctggttatca tagcccttgg ccaataaatg caaaatatcg tattcacgcg ctgtaagctc
     9241 ttcatgtaaa ttaggctgct gatcatgtgc cttaatcttc ttgtcaacct ccgtttcaat
     9301 ggcaagctcg cccttagcaa cctttctaat ggcatttaag atttcagctg cacttgatgt
     9361 ttttaacata tagcccttag ctcctgcatc aatgacaggg taaatttttt cattatcaag
     9421 ataggaggtt aacaccaaca cccttgcttc cttccatttg gagagtattt ctagggtcgc
     9481 ctctacacct cctaattcag gcattaccaa atccataacc acgacatctg gtctcaattc
     9541 aagggcaagc tcaactccct cacgaccatt agaagcctca cctatgacat caacatcttg
     9601 ctgcaaattt aagaagcttt ttaagcccat tcggaccatt tcatggtcat caactaatat
     9661 tacggttata ttactcatct tcatctccca tcacaagtgg cagtctaatg tccatcgaaa
     9721 cgccctttcc tttttgacta atcaaacgaa gcgttccagc caggtcattc acacgatctt
     9781 caatattttt aaggccatag cttaattccc taacctgacc catgtcaaaa ccaaccccat
     9841 tatcaaccat ttttagctgt agttctgttg gtgtttggtt caagtacacc tcaaggcggc
     9901 tcgccttagc atgcttgagg gtattgctga taaattcctg agcgatccta aagagattat
     9961 cctctatggc ctttggcaga gtgccaatat tttctttata gacaacctca atgccgcttt
    10021 tatcagttag ttccttgaga atcatcgtaa agccctctga caggctacga tttgccaatt
    10081 ctgtcgggcg caggtgcaat aataaaatgc gtaaatcatt ttgagcattt tgcagcatgg
    10141 cttcaacagt aactaattgt tgctgtagct gctccttatc catctgatct aggctcatag
    10201 aaacccctga caaaatcatc gacgaagcaa acaattcttg actaacagtg tcgtgcaggt
    10261 ctctagcgat tcgtttacgc tcctgttgaa taattttttg actatctaaa atataagcat
    10321 tctctttttt ctggatattg gttgttatat gagacatttt cgcagaaagt ctggtcaaat
    10381 tcgtgttgat ttcagaggtc tcctccaaat gaattctttg attgttgaga atcctgcgta
    10441 aatttttatt gatgctccgc ttgctattat catctaaaat aatccacaac aaaagcaaca
    10501 gcaaggttac agagatgata agcagcacaa ctgaaaacac caagcgctct agctgccata
    10561 aatggctccg caagtagtca aaggtgatcc ccagattatc catcacaaca aaaacaattg
    10621 ataaaatggt tatagtcgaa taaagccaga ccaaagcata ataccttttt ttcatcgtct
    10681 agccacctcg acatttcctg ctatagtgga tacgataatc ttaaccttct ttaaactgct
    10741 gtcctcggcc tctcctaggg tgatggattc atttcgtaaa tcgtactctt gaagctcaaa
    10801 aaaatcaaca ctagcataga tagagctgac ctctaaggta acagccacat caataggcac
    10861 taggatcttt gtgttgccaa agatctttct gataatgatg acattgtcca ttccagtcac
    10921 aatcacattt gtcagatcaa tcgtatcatt gccagaggca cgaataatat tgatatcctc
    10981 aaaggaataa taatcacttt catagttagc tgcgccaagc cattgatttt tgacctgtcg
    11041 cacagtcatt ttttcttctg caaaccgaat gagggcaaat cgattcttct tttttacctg
    11101 tgaaaaatga ttgataatca catacacaat ccccaacaga accgccataa taacataagg
    11161 gttcagcata aaaattaaga ataaaagcaa taagctaact gttagcaaaa agctattgcg
    11221 ggtatcttga ttataaaaac gcagagccaa taaaatcaag accaaaatta aaataaagct
    11281 tgataagtcg ttggccaaaa tggtcataat ccccatagcc agcagcatgc attcaacaag
    11341 cagaaagaat tgaaattttt tcattagact ccttccatta ccctgacatt ttatcaaaaa
    11401 ttaagcaaaa attcaccctt gagtggcatt ctagtaaaaa agaataccta gcttagcaac
    11461 tatgggcaag ccagatattc tatatcctat ttacgtttac ggtgttgtaa cagcgtcatt
    11521 ttgacctaat tcggtatgac tgcttgagtc tgttgtatct ccagctgatg gattaggagc
    11581 cgaggtatca gagctcgatg agctgcttga tgcacgtgtc tcctcagggt agaggtagag
    11641 gctaatatca cccttttcag aaaggctaat ctgggtacca taatacggtg tttgcccact
    11701 gacaaccgcc tttgagcttg gggagctcac ctgcacaaag cctgtcggag agctggagct
    11761 tggtacatag gccttgattc ttgcggcatc aattcctaaa gctgttagtg tattgactgc
    11821 atctgcatag ctgtactcag ttaccattgg catgatgact gtatcaccca ctgctacact
    11881 gagggtaatc ttggatttac cagctgggtt aaatttttct cctgcgcttg gagactggct
    11941 aataacggtg ttttcagggt attcatttgt cacgatacgc tcaatcttga tttttgactt
    12001 tggtacgcca taggtctcag tcagactggt catcacatct tgataatcct gtcccttata
    12061 attttccatc tcaaagcctt tatttccgat cgaaaggtaa aggtcaacgc tggagccttt
    12121 tcgcttagct gagccagctt gaggatttgt cttaaccacc tgatcctcac taactgtgtc
    12181 actttcaatc tgatggacct taccgacctt tagtcccgcc tcctccaaga cctgcttggc
    12241 agcattgaga ctagagcctg tcacatcagg aaccttaacc gtagttggct tggtcaagac
    12301 caaataagca aaaagagcca caccaacaac aaaaaaggaa aacaagattt ttaagagtgt
    12361 tcctagaaaa cgcccatttt ttttcttttt ttgaggcttt tgcagagtat ccatctggct
    12421 agtctgctca agtctagcat caactgccgc agatgcctga ctagcatttg ataccttagg
    12481 tgctgttaca ggagtcggtg ttacctttgg caagggcttt gtgctttcga catcatcaaa
    12541 gacaacctta cgctcacgac tgcggttata gctaagggct gtcatcaaat ccctgctcat
    12601 ctcaaaggtc gagcgataac ggtcacttag ctttttggca gtagcccgaa taacgacgtt
    12661 ttccaaggct tgaggcacat taggattttc atcaatgata gagggcagcg gcttttgaaa
    12721 atgctgcaaa gcaatcgtca cagcgctatc gccatcataa ggaatatgcc ctgttagcat
    12781 ttcaaagagc ataattccca tcgcgtaaat atcactttga atcgtcgctt tagaaccacg
    12841 cgcttgctca ggtgagaggt aatgcacact tcctagcata gaatttgtct gggttagact
    12901 ggtctctgca aaggcaacgg caatcccaaa atctgtaacc ttaacaacac ttgatttggt
    12961 caaaagaatg ttttgaggct ttaaatccct gtgaacaatt cctttttggt gggccagagt
    13021 catggcagaa agaacctctt ccatgattct caccacctca ttgttagata atggcgcatg
    13081 atcctgaatg tattttttca agtcagagcc atcaacatat tccattacta aaaattgctg
    13141 tccgtcttcc tcgcctatat cccgaatggc aacaatattg gggtgattta attcagccat
    13201 ggctcgcgct tctctttgaa aacgcgcaac agcaacctga tctgtttgat aattggtccg
    13261 caagacctta atggcaacgt cctcattatc cagaatcaaa tcgtttgcta aataaacatc
    13321 cgccatacca ccgcggccta tagattttag aatgcgataa cgaccagcaa atagcttgcc
    13381 aatctgaatc attctgcttc cccgctttcc ttatgcacca aagcaacggt gatgttgtct
    13441 aggcctcctc tttggtttgc caggtcaatc aaggcttgat ttttctcatc aaggctgatg
    13501 tcttgacata atatgtcaac aatctcctca ttagcaatca tattggttaa gccatcacta
    13561 ttaatcacta ggtaatcgcc cttttctaaa accttgacac ctaagtctgg ctctaccggt
    13621 gaagcttgac ctatagattg tgtgatgata tttttttgtg ggtggctagc agcctcctct
    13681 tcggtaatct gaccagcctt cactagggca ttaaccaagg aatgatcact ggttaaaaga
    13741 ctataatttc cctcatgaac caagccgata cgagaatcgc caatatgggc ataaatcgca
    13801 ttagaatcta ctagagcaac tgcctcaacg gttgttccca ttcccttata gtcttcagat
    13861 tgtcccaagt cgtagatacg ttggttctct gcttcgatgg ttgttaacaa ccaatccttg
    13921 atctgactaa gctcagtaaa atctgtctta acccactctc tacctaggtc tgtaacggtc
    13981 atctcactgg caatatttcc tgccctatga cctcccatac catctgctag gataacaagg
    14041 gtaatgcctt ttttattatc aaatttgttg ataaaatctt gattgtttga gcgcttttgc
    14101 ccaatatcgg tttttaatga aatcttcata taatcttttc tgactaggtc agtctcctcc
    14161 taaatactac aagactcgtc tgacttgccc aataaagaag ccatcagtct ggtattgctc
    14221 tggtgtaatc ataagacaac cgtccttgac aatatctgct tgtgcatgct tgagtgttac
    14281 ttgttcaaaa ttaggatgac gttgtaaaaa tttgtcaata acttggaaat tctcttcatc
    14341 aaaaatcgta caagtgctat aggttattat accacctttt cgcagcgttt gacaaacgct
    14401 agacaatatc tccagctgaa tttcctgcaa ttgctggaag tcctgccctt ccttgttgta
    14461 tttaatatct ggcttacgcc tgatgaggcc tataccagag cagggagcat caactaaaat
    14521 cttatcaaag ctgttcttcg caaaatgctt atgaacctct ctagcatcaa gcaccttagt
    14581 ttcaatccga tctgctaccc ctagacgctt agcattttca ttcactaagg ccagcttgtg
    14641 ctcatacaaa tcaagggcca ctactttgcc gctcgtcaaa taagaggcaa tgtgagctgt
    14701 tttccctccg ggtgcactac aagcatctaa aatcatttcc tgcccttgaa tatccagcgt
    14761 cggggcaact agctgactgg tctcatcttg gatcgtaatg tccccattga tgaaataact
    14821 gctggcagca aaattgccag ctctcttggt cagaccagtc ctagcaagta atgattgctc
    14881 tgatcctgtt gcctgcttga tctcatcaag ctttgtcaga tctgtgacac gtatgctggc
    14941 tctgcttctc acaaaaagac tttccatgat tgctacagct cgctcctcgc caaattggtc
    15001 gatcaatttt ttgactagcc agaccggtac tgagtaagca acagcatagt atttgttttt
    15061 tcgcttgatg ctcttgatat ctggtaaggg cttattggtc agctggcgca aaacggcatt
    15121 gaccagctta tctgctcctc tgccatgagc tctcgccttg gcaagattaa cagcgtcatt
    15181 aacaatagca tgagcaggca ccttgtctag gtaagccagc tggtaaaggc taagcatcaa
    15241 gagataataa acccatttat ccagcctgtc tcggtcctca atatagtgag ccagatacca
    15301 ttctagggtt atcttcctag agatagtccc gtaaacaatc tctgtgacta gagccttgtc
    15361 cttatcactt aaaaactgat tcgccagctg gtgcttcaag gcaaggttag aataggctcc
    15421 atgatcaaaa atatcctcaa cgataagcag cgcctgtcct ctagctgatt ttttccaatc
    15481 attcgccaag gacatcaccc acctctaggc ttctgccaat accatttaaa aagtcaacaa
    15541 taggcatctt tggcttgcct gctggttgaa cgagcgtcaa ggatagagcc ccctcacctg
    15601 ctgctacgac caatgctttt ttagttttag cgatgatttg cccagcagat ccagagcctt
    15661 cagccaattc agcctcataa attttgaagc gctgcccatc taataaggta tgagccaccg
    15721 gccaagggtt cattcctctg atatgattaa acacctctct tgctggcttt gaccagtcca
    15781 gtctttcttc ttctgctgaa agattgggag aaaaggtggc ttggctatgg tcttgaggaa
    15841 ctggctttag gtcaccagac aagtaatcag gcaaggtttt caataataaa tctcgtccta
    15901 gaatggccag cttatcaaac atggtaccaa cattatcagt atctaaaatt ggaaggcttg
    15961 cgcttgatat catatcccca gcgtccatct ccttaaccat ctccataatg gtaactccag
    16021 cttccttgtc accattgata atagcataat ggatcggagc gccaccacga tatttaggaa
    16081 gtaaggacgc gtgcacatta acagcaaatg tcaccgaatc caataagact gttggtaaaa
    16141 attgcccaaa ggctgccgtt acaatcccgt ctgctcctaa tgccatgata tctgctagct
    16201 cctgtgaacc agatagcttc tcaggctgaa aaacaggcag ctgatgtgca agcgccagct
    16261 ttttaacagg cgtcattgtg atgtcttttt tgcgaccaac cgcacgatca ggctgggtca
    16321 cgaccgctaa aatgtcatag gctggttttt ctagtaagcc ctgcaaaaca gttgctgaaa
    16381 attggggagt gcccataaaa attaatcttg tcatctatgt cctctatttt ctttcttttt
    16441 cattatagca tagcttggcg caaagtccgg taaagaacac ttacataaag ctctgtggct
    16501 cctgatcaat gataaccttt agctcgcgat tatcctgctc ttggctccaa tcaagaattt
    16561 gattcagggt agcttcaagc tgatcctcaa agcgatactt caaaataatc tgataatggt
    16621 aaagattgtg cgttcttgca attggctttg gcgttggccc taatattctg atctgatcag
    16681 acaagccctg cttcaatatg gtcagcagtt gataggcctt tttgaccacc tcttgctcac
    16741 tcttatgcga tagggtcaga cctactgtga aataataggg aggatagcct agctttcgtc
    16801 gaatccccat ttcataagcg taaaaggctt caaaatcctg ctttttggcc agttgaatcg
    16861 cgtaatgctc aggattgtag gtctgaatca ggacttcacc tggcttgtct gcacgtcctg
    16921 cacgtcctgc aacctgagtc agcaattgaa aggttcgctc cgatgcccta aaatcaggta
    16981 aatgcaagga agtatctgca tttaaaacac ctactagggt gacgttggga aaatccaacc
    17041 cctttgcaat catttgtgtc ccaagcagca catcagcatc accatttcca aactggctta
    17101 aaatagcctc atggcttcct tttttacgtg tcgtgtctac gtccattcgt aatattctag
    17161 cttccggcaa cacttgcttg agctcatcat aggctttttg cgtccctgtt ccataatagc
    17221 gtatgctttt gccttgacag ctagggcata gcttcggaat agccctttga aagccgcaat
    17281 agtgacaatt catggttttc gtatccatgt ggagggttaa ggaaatatca caatttggac
    17341 attgatcaac atagccacaa tctcgacaca tgataaagct agagtagcca cgcctgttga
    17401 gcatcaaaac agcctgctct tttctagcaa gacgctcttt gagtttatca atcaaataag
    17461 gggtgaagct gctaacctcc tgctgaccaa tataatctcg aaaatcaaca atctcaacct
    17521 gaggcatact ggcaagagga ttggctctct cagtcagctg gataaactga tacagtccct
    17581 tgctggctct agcgcgacta tcaatactag gggtcgctga gcccatcact aaggcagcct
    17641 tatggtgcct tgcacgaatg agagctacat ctctggcatg gtatctggga ttagattcct
    17701 gcttgtaggt ggcctcatgc tcctcatcaa taataatggc tccaatattt tctaaaggtg
    17761 aaaaaatagc agagcgagca ccgaccacca ctctagcctg ccctgtctta attttctgcc
    17821 attcgtcaaa tttttctcca tctgacaaac ctgaatgcat aatagcgacc tgtcttccaa
    17881 agcgggaaat aaatcgagag gtcatttgag gcgtgaggga gatttctggc actaagacaa
    17941 tagctgtctt tccttgctca agcacatgcg caatcacatg aagatagacc tctgtcttgc
    18001 cagagcctgt aataccttcc agtaaaaagg gcttagcctc tctgccaaca gccttcgtaa
    18061 tctggtcaac agcttgctgc tgctgctgat taagctttaa gagtggggct gccttgatgt
    18121 gattgaaata atcctcactg cgattgacac gtcgctcctc aagctcgatc agctggttgg
    18181 tcacaaaata gctaacaacc tctctagaat aatcctgata aagcttggct agcttatctt
    18241 tttgtggatt ggctaacaaa taagccttta aggcttggcg ctttttagcc cgatttgaaa
    18301 tcttatgctc ctgtaaggct aatctattga cctgatagta agtctcggtt ttgattgtct
    18361 ttttgtcctt ggctagataa gttgccctaa tcttaccaga ctgtatcagc ctaaggacac
    18421 gtccctcctg ctctggactt agcttagaat aaagcaagga atccccatta gagaaaacat
    18481 cagcaaggtc agccgcagct aagtcagctg tcggggtgag cagccgatcg taatgagaat
    18541 taagtaggct aggaagcatt gcctttaaga gggtgatttt gtaggaaaag actgtttgtc
    18601 gtaattgctc tgctaatgcc acctgctcct gatttaaaac aggctcagca tctaaaactg
    18661 accaaatagc cttcaattgc tgcgttgatt gactagaaaa gccaataaca aagccctgta
    18721 gcaacctatt gccattacca aaaggcacat gaacgcgaga accaatctta accagagata
    18781 atagctcatc tggaataaga taagaaaagg gcttatcggt ttgcatcaag ggaatatcaa
    18841 caatgacctg tgctatgtgt tgcattttga cttcctttct atcaagaaat ggacctgcaa
    18901 tatgaaaaaa actaagattg actcaacctt agattttttc tccctcttct tctttttctt
    18961 ttgcaatctg ctcttttatt ttacgctctt cttcttctct tgctaaacgc tctgcctcaa
    19021 accttgcacg aacagccgca cgcttagcag caggatccgg gtgaatcaca acattgcctg
    19081 actcaatctc ctctagtgcc tgaagtgttg atttgacaga cttaaaggac tgtgtcggtg
    19141 cagcacctgc ttctaattca tgagcacgct tggcctgtaa aataacaagt gaatattttg
    19201 atgggacttt atctaataaa gtatcaattg aaggttttaa catcatgggc tttactcttt
    19261 tctatttcta tcatctgaga gattttgttg ttttaatcat ttgatcatag cgaccaatca
    19321 cacgctcaac gcgaaaatgc tcggtctcaa taatacgctt gacacgctct gcagctaaag
    19381 gaacctcgtc gttgaccaca gcataatcat actctcgcat gagcgcaatc tcttccttag
    19441 ctctttcgat acgcttggca atcacctctt ggctgtctgt tccacgacca accaaacggt
    19501 cctgcaattc atctaagtct ggcggcgtta gaaaaatgaa gacaccatca ggcaccttag
    19561 ccttgacctg caaagcaccc tgtacctcaa tttccaaaaa gacatcaatg cccttatcaa
    19621 gggtttcgtt aacataggtt aagggagtgc catagtaatt gccgacatac tctgcatatt
    19681 ctagcatttg accatttttt attagctctt caaattcttc tcgtgtgcgg aagaaataat
    19741 caaccccatc aacttcacct ggtctctgtg gacgtgtcgt catcgaaaca gaatattcaa
    19801 atttatgatc tggcgttgaa aaaatctctt gtctcaccgt tccctttccg acacctgagg
    19861 ggccagagaa aacgattaac aaaccgcgtt cagacattgt gttctcctta ttgattgctt
    19921 tctaatagtt tatcaaaaag gctatcgttt ttcaagacaa ttatcagccc aatcctaaga
    19981 aagaaaagga agagatagac gccttctcaa agctagaggc taaactctgg cttttgaaaa
    20041 gcatacactc tttccttttt atttcgcata atctattgct cgcaactcac gaataacagt
    20101 taccttgata tttcctgggt aatccaagtt attttcaatc ttttctctta ccttgtgtga
    20161 gagaaccaca atctcgtcat cagaaatctt ttctggctga accatgatgc gaatctcacg
    20221 accggcttgg agggcaaagc tactttgaac accatcaaag cttgttgcga tttcttcaag
    20281 gtcacgaaga cgcttgatat agttttccac agattcattg cgggcacctg gacgagcaga
    20341 gctaagggca tcagcagcag ctaccagaac tgcaataacc gaatccggct cgacatcgcc
    20401 atgatggctg gctatggtgt tcacaacaac agggtgctcc ttgtacttgc gagcaaactc
    20461 cataccaatc tcaacgtggc ttccttcaac ctcacgatca atagccttgc ccatatcatg
    20521 caagaaacct gcgcgacgtg caagtgccac attttcacca agctcgccag ctaaaatacc
    20581 agctagctta ccaacctcga ctgagtggcg taaaacattt tgaccaaatg aggtacgaaa
    20641 ctgtaagcgc cccatgatct taatcaaatc cgggtggagg ttaggtgcac cgatctcata
    20701 ggcagcagcc tcaccatact cacgaatcct attgtccatc tcaagacgat ttttctcaac
    20761 caattcctcg atacgcgccg ggtgaatacg accatcagca atcaaggact ctagggtcat
    20821 acgagcaatc tctcgacgaa tagggtcaaa gcctgataaa acaaccactt ccggggtatc
    20881 gtcaatgatc acatcaatcc ctgtcagact ctctagagta cggatattgc gaccctctcg
    20941 accgataata cgccctttca tgttatcatc aggcaagtgc acacttgtaa tcgtctgctc
    21001 agtcacatac tcaccagcca tacgttgcat ggcctgtgct aacaggtcct tagcagtctt
    21061 gtctgtcctg tccttgatgt cacgctctgc atcacgaatg cgtgttgcga tctcatgcgt
    21121 cagcttgttt tcagtttcca tcaggataac ctcacgcgct tctgcaatgg tcatagcagc
    21181 aactcgttgg agctctgctc ttttgtcttc ctcaagtttt tcaacctgtg cctgtcgctc
    21241 atcaatgtgc ttagatttat cggtcagact ttgctctttg ctatctagta ctttttcttt
    21301 acttgataga ttttcatcct tacgatcaag agttagagca cgctctgcca agcgcgtctc
    21361 cagctgttta agctcttgtc tttcagattt aaattcctgt tcaatttctt cacgatactt
    21421 tcttgcctct tcctttgctt ctaaaagtaa ttctttacga cttgctttac tttcacgttg
    21481 tgctgtcttt ttgatatgag cggcatcggc ctttgccttg ccacgaatat caacagcatc
    21541 ctgttcagcg tttaaaagag tcaactctgc agcttccttc gcagacttga gtctaatcga
    21601 aataagtgca taacctaata ttacaccaat gaggccacag acaagtaacg ttatgatatt
    21661 aattaacatg tctttacctc aataatagtt tagttttcat taacagaaag ccatctctta
    21721 gtctatcata aaatgaagat ttagacaatt taaaatccac ctacattttt ctaaaatcta
    21781 gtgattttat gttatgatat tgataaaaat aaaaaggagt ttcttatgcc aaaagaagtt
    21841 attgttgaaa gctttgagct tgatcatact attgttaagg caccctatgt acggctaatc
    21901 tccgaggaat ttgggcccca gggagatgtg attacaaatt ttgatgttcg acttgttcag
    21961 cctaatcagg ctgccattga gactgccggt ttacatacca ttgagcattt attagccaag
    22021 ctcattcgtc aacgcattga tggaatgatt gattgctccc cctttggctg ccgcacaggc
    22081 tttcacctca tcatgtgggg caagcatagc tcaacagata ttgctaagat catcacgtcc
    22141 agcctagagg aaattgctac aagcatcact tgggaggacg ttcctggcac aaccattgaa
    22201 tcctgcggca attataagga tcacagcctt tttgctgcta aggaatgggc acagcttatt
    22261 ctcaagcaag ggatctctga tgatccattt aaccgccatg tcacctcata aaacgaaagc
    22321 ctctcttttc tgctaatgtg aaggaggctt ttaatgtatt caaaaaggtg ccaaaggcaa
    22381 ggctcaatgc ccttaccttt agcacctgtg ataactagag tatccagttc aggatcacac
    22441 cttgtcttct aagcattaat agtctaagtc ctctgcatgc cccttgccat ttccgacaaa
    22501 atagcctgtt ttgcaattca atgaaaagag gtaggtgcca tcaggcttaa acatgttgta
    22561 atagccattc ccattgataa tattgaccgg ctctaggata taatcattgc ctgaaatata
    22621 gccccttgct tgtgaggtag ccacaatacg ctcaagcaca cctggattaa aggcccaagc
    22681 agggtttcct gtatcagcaa tcatagcctg attgtagggc acacgagaca ggtcacgctg
    22741 caatattgaa gggtcatagc ctgtaatgcc atacattgga gccactggag ctggtacagc
    22801 aggaacctgc ggagctgcag ggcttgctgg taaggcagaa gcagctggag tgctagctgc
    22861 ttgggtagca gacctgcttg ctagctgctc acgacctgcc ttgatgcttg attgtagcaa
    22921 tgaatcaagt tttgcattac cagtggttag cgtatcacta gctaggtcat caaaattagc
    22981 atcagctttg acctcagctg caatcttttc accattgaca attgcagctg ttgtaaattt
    23041 cccattaacc gcctgaatag ctgttacttg ctttttcagc ccagtaacct tttccttagc
    23101 cttgtcataa taggctgtcc cttcaagcct ttttaaagca gtctccaaat tcggtaactg
    23161 atcaaaggcg ctatttttta gggttgtttt atcattatct gtgaaaaatg tcttgtaaag
    23221 atcttcaaaa gccttagcat tagcctttgt tttgttggtc tgattagctg ttgatgcttt
    23281 gctccttgct tttttagaaa cagtagcctt tgactgaggc ttatgcttag acagctgata
    23341 gatatggttg agggcaaagg ctgaggctac aagggttagc gtggctaaca aaatagcaaa
    23401 cagaggcttt ttctttttag acctacgact agcatagcta tctgataaaa tactctctac
    23461 ttctgcaggt cgctcgctaa ctgcgtcatc agctagctgc ccagtaaaat cactagcaga
    23521 atcagtagct gccgctgaag tgtcagctct agctgctaga ggctcaatga atgaggtctc
    23581 accggctggc ttctcctctg ttgaagcctc gtccactggc tcaacatcaa ctaagccggc
    23641 tttgctgagc tcctctcttt gttttttgat aaagttatcc agacttgctg tatctaactc
    23701 catatacttt gcatcaaact tttgtgatga cacttcgtta cgatgccgct taatatattt
    23761 gtctaaaaca ctatcatcct cggtaatccc tgcttttagc tctgagtcct tgcgtactgc
    23821 ctcaccgatt gtcatttttt tggcttcatg aagctccaaa ttttggcttt ctgcctctga
    23881 ttcaaatgct ttgctttttt ctgacacgtt ttttacctct ctatatcaga ttgcgcttta
    23941 ccctctctcc ataaaattga tacaaatcaa cccttagagt accattataa agcttacgtt
    24001 ttttatcagc tttttgacca tatttttgtt caaaatgatc atcactcgtc aaaataaact
    24061 tgctccaggt aactaatgga gcaaagacct gtaccatctc attatacaag atgtctactg
    24121 ctttgtcatc aagcaaacgc tctccataag gaggatttga aatgatgaca ccgtttatct
    24181 tgtctgtacg gaaatcctgc aagcgcattt gcttaaaggt aatgatatca gccaagccag
    24241 cctcctcagc atttctcttg gcaagctcaa ccatacgacc gtcaatatca aagcctgaaa
    24301 tatccagctc aatatcataa ttagcctctt tttcagcagc gtcacgaacc ttttgaacac
    24361 gatctttgtc cacccagctc cattcctcaa aggcaaagga gcgattaaag ccaggagcga
    24421 tattcattcc gatgagagcc gcctcgatac aaaaggtccc cgatccacag gtgggatcaa
    24481 ccaagggctt atccggaaac caattagaca gcttgaggat agctgctgcc atgttttcct
    24541 taataggagc tccccctttt tccacccggt agccacgctt aaataggctt gagccactag
    24601 tatcaatcat cagggtagcc tgatccttta agattgagac ctcaattttg aactcagccc
    24661 ccacctcttg aaggggaata tgctccggtc tatgaaaatg ctgctgcaat tttctgacaa
    24721 tggctttttt ggtaatggct tgaacacttg gctcgttgtg cagggttgac ctgacacact
    24781 tagcctttgc aataggaaac ctagcaccta agggcaaata atgctcccaa tccaaggcaa
    24841 atacgccctg aaacagctcc tcaaagcttc gtgctgggaa ctgacctaca ataatcttaa
    24901 tacggtcagc cgctcgcagc caaagatttg ctttagcaat agcttcaata tcgccttcaa
    24961 agaagacctt gccattatct actcggcagt caaatcccaa ggcccttaat tccttaccca
    25021 caacagcctc taggccagct gctgcagttg ctactaatgt aaattgttct ttcatatgac
    25081 tctttctatc ctaaccaaat aaaagctagc atatgctagc ttaacctatt atgcaatttt
    25141 ctataagcca tgttttgttc cagaaataac taggtattat ctccttcgat aatcatctgt
    25201 ctactgtttg tcaacagtca ggatagcttg ttcgtttcca actatcccat gcccctacca
    25261 aagtttgggt tgctagcttg aggggtttac cgcgttccac tttttacgtt tccataaaaa
    25321 cttcgtcact gtggcacttt cagagctact ctggcatatc aaggacttag ccttttcact
    25381 cgccgtaatg tgtcaaacac atccctaggc ttatttgttc gcctagcaca aacactacca
    25441 gcatcacagc cggtgctagc atggactttc ctcatagtat tgcaatacta cgcgattatc
    25501 caaaaattgc acatctacat tactcaataa tttgctttcc aaaaacctct ttttccagct
    25561 tgctaatgcg ctttagcatg tcaaaattgg tggctgactg tgctactctg gttggctgtg
    25621 ataccgcctg agagctgcct gctaaaggat cacgcacctg agccttagcc ttttttaagg
    25681 cttcattttc agcctttagg gcctcgatct gagcattgaa atactcataa tccttgatga
    25741 cgttatcaag gaattcgtcg acctccttct tatcaaagcc acgcatactg gtcttaaatt
    25801 cttgctcaaa aatgtccttt ggactataaa ttatacctgt cattctatac tctccaaacg
    25861 gtcaatcttt ttcaaatatc aaactttgat atcactactt atgatacaga aaaataaatt
    25921 aaaaagcaag tatttaaata ccagtgattt ttaaatatca ctagctactc atctgcaatg
    25981 tcatttaaac gctcaaagtt taggaaagaa agggggtaac agggctgctc cttcatagct
    26041 gctaccaaat agcttaggcg cgtttcgtgc tcactatcat aaaaaagata ggctccgtct
    26101 gtattgtgaa tcaaaaagtg atggtagctc tttagctgtt tagggctttc atagctggga
    26161 tagctatatt tgacaaaatc agtctcccga aattgctgca gctgctgctg attgcgatca
    26221 ttccaagtgc tgccatgcgt ttcaaaggca aaaatagtcg ctgtctttaa ggggtaggtc
    26281 tttttgaggt cattagctac ctctaaagcc cactgctcaa accctaaatt cccagtaaaa
    26341 ataaaccagt ctaccccctc ctcaagataa gcaatcagat ctctttctat cgcttttttg
    26401 ataatggcaa ctcttttatc cttttcacta aagatgccca gctcaaaact tcgatagcct
    26461 gttacgagaa ttgcagtcat tagatgttat cctttcaaaa atatgttata atgtgaatgc
    26521 ttaaattatt attaagtcat gatgttagga gaacaatggt taactaccct cataatccta
    26581 ttcgccaaaa ggtgacccct cttcaaaagc agcaaaagca caagcaagta gactttgcta
    26641 atcgtggtat gtcctttgaa gcatccatta atgcaaccaa cgcttattac ttggccaagg
    26701 gcattgctgt cattcataaa aagccaactc cgatacagat tgtcaaggta gactatccaa
    26761 gacgtagtcg agccaagatt gttgaggctt attttaagca ggcttcaacg accgactatt
    26821 ctggtatcta caaagggcat tatattgatt ttgaagctaa ggaaacaaga caaaaaacag
    26881 ctatgccaat gaaaaacttt cacgcgcatc agattgagca catggctgct gttttaaagc
    26941 aaaaaggcat ttgctttgtc ctccttcact ttgcgacact aaaggaaacc tattatctac
    27001 ctgccaaagc actcattgat ttttatcaga ttgatagggg caacaaatca atgccacttg
    27061 attatatcag aaaaaacggc tttgaggtca agctgggagc atttccacag gttccttatt
    27121 tagatattat agaacaaaaa tttttaggcg gtgattacaa ttaacaatcc aaaaatcctt
    27181 aaattcctga agtatacatt aggtgctatc cttagcctta tcattgtgac aattacctta
    27241 ggtggccttt tgtttgctta ctatatcagc agtgccccta agctttctga ggcccagctc
    27301 aaatcgacca attccagtct tgtttatgac ggtaataatc atttgattgc tgacttgggc
    27361 tctgaaaagc gtgaaaatgt tacagctgac agcattccta ttaatctggt caatgctatt
    27421 atttctatag aagacaaacg cttttttaat catcgggggg ttgatctcta tcgtatctta
    27481 ggtgcagcct ttcacaattt aacaagcaaa acaacccaag gggggtctac acttgatcag
    27541 cagctgatta agctagccta cttctcgaca aacgagtctg accagacctt gaagcgaaaa
    27601 gctcaggagg tttggctggc ccttcaaatg gagcgaaaat ataccaagca agaaatcctg
    27661 accttctaca tcaacaaggt ttatatggga aatggtaatt atggtatgct gacagcagcc
    27721 aaggcttatt atggcaagga tttgaaagat ttgtcctatg ctcagctagc cttgctggca
    27781 gggattccac aggccccaag ccagtatgac ccctacacac agcctgagac agctcaaagc
    27841 cgccgaaata ttgtccttca gcaaatgtat gctgaaaaga acattaccaa ggctgagtac
    27901 gaagcagcta tcgccacacc tatatcagaa ggcctacagc ctctccagca acgcgccagc
    27961 tatccaaaat atatggataa ttacttaaaa caggtgatcg agcaggtaaa ggctgagacc
    28021 aacaaggata tctttacctc tggtctaaag gtttacacaa acatcattcc agaggctcaa
    28081 aaaaaacttt atgacattta caattctgag gactatgtgt attaccctga tgctgacttt
    28141 caggttgcct caaccgttat tgatgtcaca aatggacacg ttatcgccca attaggagga
    28201 cgcaatcagg ataccaacgt ttcctttgga accaatcagg ctgtcttaac cgatcgtgac
    28261 tggggatcca ccatgaagcc gatcacagac tatggacctg ccattgagtc cggtgcttac
    28321 aattctacag ctcaaacaac taacgactct gtctactatt ggccggggac acacactcag
    28381 ctctataact gggaccggag atactatggt tggatgacca ttcaagctgc tctcatgcaa
    28441 tcacgaaacg tccctgcagt tagggctcta gaggcggcag gtcttagcta tgcacagtcc
    28501 ttcctcagtg atctaggcat taattatcca gagatgcatt attcaaacgc catctcaagt
    28561 aacaatagca gttctgattc aaaatacggt gcaagcagtg aaaaaatggc tgctgcctat
    28621 gcagcttttg ccaacggtgg actctattac aagccacaat acgtcaataa aattgaattc
    28681 agcgatggga ccagcaaggt catcgaaaat aagggcaagc gtgccatgaa agaaacaaca
    28741 gcctatatga tgactgatat gctaaaaacg gtactaacct acggtacagg tactgctgct
    28801 gctatcccag gagttgcaca ggctggtaaa actggtacct caaactatac cgatgaggag
    28861 ctggcacaaa ttgttgagac acatggacta tctcctgatt acgtgggaac aatggcgcca
    28921 gatgaaaact ttgtcggcta caccaaccga tacgctatgg cggtttggac tggttataaa
    28981 aaccgtatga cgccaattta tggctacagc ctagaaattg cttctcatgt ttatcgcaac
    29041 atgatcagct atctcaccgg cggctacagc gacgattgga ccatgccaag tgggctctat
    29101 cgtagcggcg gcttcctcta cctaagtggt acctatacaa acagtagcga ttatacaagc
    29161 tctgtctaca acaacctcta tggtaataac agctcagctt caagccaatc ctcagatgag
    29221 gatacaactg aagacagcca ctcagaagca aacgacagca caacgtcatc atcagagcag
    29281 caatcaagct ccaccgatga taagaaaacc aactgataac aaaaaactgg ttcaaatgtt
    29341 ctgaaccagt tttttcaatt atttggctaa ggcacccatc ggatcccaag gggcaagtac
    29401 ctgtggttct gcctcatagg ctgctaattc atcagctgtt agtaggtcct tgcgaacaac
    29461 aatctggtaa gtatactcgt ccatccaagc atcagaagca acaaagtatc ctttgtcacc
    29521 aaccttgtct ccccaagaat tttcaacctt ccatttgata ggcttaccag tatcatctaa
    29581 atcaacacct gtcaaaacca tagcatgtgt cattaagctt tcgctgtaat caaggcgacc
    29641 agccttgtct tggctcaact gaatatccat acctgcctga aaatcatagg tattaagggc
    29701 tagaatcccc ttttgacgat ctgatacctg accaacgtct gaaccaaacc aaacggactc
    29761 tccagcctgc atttgcttaa tagcaagctc cttgaagcgc tccatatcaa gattaaggta
    29821 gcgcacctca ggactgccaa caacattacc aagcatatca accgtataag atttgccata
    29881 aggcttatca gctgttgggg cgttgataac agacacataa tcagacagct ttagaccaac
    29941 atatttttca taaaatgcct gtggtgtgat gcccttatca gcatgatagt gattatcctt
    30001 atcacgataa gcaaaatcaa attgacgagg tggcaaacca agattcatgg ctaagaaatt
    30061 aaagatttcc tgaagtagct cttctttttt agcctgtact gcctgatgat cagcaccagc
    30121 actgatcaca tctcgaagaa tctgagcgtc ctgacgcaag agcttattga ggtattgatt
    30181 tagctcacga ctattgcttg atgacacaga ctctgggtag actgattttg gcacaacacc
    30241 gtatttttca aacagggcta caaccatgtc ccactgacca ccgtcttgct gcggaacgtc
    30301 caaaagaaac ttaaccctac ggctagtcaa ggcttgatca gcagttgcaa tcacctgttc
    30361 cataaaccag tttgattttt cgtatttgtc ccagaaaaag gtgtgtgctt gtgacaactc
    30421 aaaatcttct aatttaaatt ctgaaataag cttatggcga aaggtgttta aggctgcaaa
    30481 catccagcaa cgacctgaag ccttttgatt agagacctta tcctttgtca agtcaatgga
    30541 aaagacaaaa tcattgtcga tctcactttg tcttgtctcc aaggatttaa gcaagccatt
    30601 gtgagtgatg gcattttcaa gagctaaata tttagcatta gcttcataat tagcatatag
    30661 ctgttctgta aatgtctctg ttaatactga catcattttc ctccaaagat aataaataac
    30721 aacacctaaa aataaagttg acagaaaaat ccataaatac tgtcaatttc attttcaagg
    30781 attacttcta ttatagacct tatttgatat tcttcaagta aaaaaattag gctaacttaa
    30841 ttttttaaag ctaagcagca gctttccaat aaccagacaa aaagccatct caaaagacga
    30901 caaaacctgc tggactttga gcacctaaac atgtcatatg tccacctcag catgaactca
    30961 aagaagctag ctgtgtctgg ctatgacttc agtttaatca ttagcttgcc ttagccacaa
    31021 aaagaatcgt ctccactgta gcaaaagtgc ttgatataac accatcggct aagtcaaggg
    31081 gcccctgata gttaactgaa acatatggca aagctaaaac caaagacttc ttctccttaa
    31141 agcctctggt ttttagttag ctgagcattc tcctttatct tggctgcttt aagataggga
    31201 caaatcaaca actaccccaa tcccatttac aaaaaagccc taagtcagag ccttcatagg
    31261 gctaagggtg agggaagctc ttaggcaaca gctactggat ttatgcctaa tagaagctcc
    31321 tgtccctcct cacctattta aaatagcatt ggtttatcta tagcctgtgt aggtttgagg
    31381 atcacttcca aaagtcatca aaaatagtaa ttggcagatg gcgcttgtgc tgccctttat
    31441 gccaccagtc ttcaatcctt gcctgagctt cagcggaaat cgtatgcccc tctaagtaat
    31501 catctatctc ttgataagta acacctaatg ctacctcatc tgcaagtcct ggcttcttat
    31561 cctctagatc tgctgttggc accttctcat agaggctggg gtcagccttt agcaccttta
    31621 acaaggcctt accctgccgc ttagtcaagc gaaaaagggg tagaatatcc gctccgccat
    31681 caccaaactt agtgaaaaag cccgtaacat tttcggcggc atgatctgtc ccaatgacag
    31741 caccagctgt ttgaccagcg atagcatact gactaatcat acgctgacgt gccttaatgt
    31801 ttcccttatt aaagtcagaa atctcaagcc ctgccgcctc taaggctctt agctgaccat
    31861 caacagcctc tttaatatta accgtcaagg cttgatcagg ttgaataaat gctaaggctt
    31921 tttgtgcatc tgcctcatct gcctgaacac catagggcaa gcggacagcg ataaattggt
    31981 actgctcatc acctgtttca gcgcgcagct cttcaatcgc catctgagct agctttccgg
    32041 ctaagctgga atcctgacca ccagaaatcc ctaagacata agtctttaaa aaagggtgct
    32101 ttaacaaata agcctttaaa aaatcaaccg actggcgaat ctcctgctta ggatcaatta
    32161 ctgctttgac ctcaagctga cgaatgatat cctcttgtaa tgtcatatca aatcactcct
    32221 tttacaggct tccttgcgga ttttgtcaat aagatgcatc ttattttgcc aaacatcaag
    32281 cgcaagatcc acagggtaat gctgcggatt caagacacgc ttatattcgt cccaaagctt
    32341 atcaaattcc tttctagcat aagccttgat gtcttttaag cttggcagct gataaacgag
    32401 ctttccttta tcaaaaatat ctactagcaa aggaacagca tcaaaatctc tgacggtttt
    32461 attaatgtag gtataagtcg ggtggaacat gtgaatttcc tctaggtcat tgacattaac
    32521 acctgtaaag gtgatgtaat cgccttctga cttgcccttt tcgcggctgg taattcgcca
    32581 aacctgcttt ttacctggtg ttgatacctt ttctgcatta tttgatagct tgatagtatc
    32641 gcgcatggta ccatctgcct gctctatcga aacaatctta taaaccgctc ccagagctgg
    32701 ttgatcatag gctgtaatca attttgttcc aacaccccaa acgtcaattt tagctttttg
    32761 cattttcagg ttgagaattg tattttcatc taaatcattg gaagcgtaaa tcttagcctc
    32821 tgtgaagccg gcagcatcca gctgctggcg taccctttta gataggtaag caaggtcacc
    32881 agaatccaga cgaacaccca agaaattaat cttatcacct aattccttgg ccacacgaat
    32941 agctgttggg acacctaccc tcaaggtatc ataggtatca accaagaaaa tacaatcctt
    33001 gtgcacactg gcataggcct tgaaagcatc ataatcatta ccataggcct gtaccagagc
    33061 atgtgcatgc gtgccagaca caggaatgtc aaaacgcttt ccggcacgaa cgttactagt
    33121 tgcgtctgct ccgccaataa tggcagcacg tgtcccccaa acagcagcgt ccatctcctg
    33181 agcgcggcgt gtcccaaact ctaaaagtgg ctcatcttca ataacagagc gaatacgagc
    33241 tgcctttgta gcaatcaagg tttggaaatt cacgatattc aaaagagctg tttctactag
    33301 ctgacattga cctaaaggtc cctcaacctg aacaataggc tcattggcaa agaccaagtc
    33361 tccctcttgt gctgagcgaa tcgttagctc taaacgaagc tctctgagat aggtcaaaaa
    33421 agcagggctg tagcctagct ccttcaaata agccaaatcg gtctcagaaa aggtcaattg
    33481 ctcaaggtat tctacgattc gttgtagacc agcaaaaact gcatagccat tgttaaaagg
    33541 ctctctacga aaataaacct caaagacagc attacgatta tgaatgccct gctcaaaata
    33601 aacctgcatc atatttaatt gatataaatc agtatgaagg gttaagctat catctctgta
    33661 catataagta actccttaac ataattgtta ttattatacc atatttttgg catagacctg
    33721 taagattcaa ctaaaatcct ctgctcaagc tttctaaaaa agaagccttg agctgctatt
    33781 aagcctgaca tattttttgc cagtaccttc ctaaaaagtc tatagcacaa gggcttatgg
    33841 ctttttaaca aaagcagttt cagttgatag cattcataaa aaaagattga agaaattgac
    33901 caaaatagcc cctttcttca atctatttaa ctcacacctt agccttttaa cgctttttta
    33961 cacttgagct gactgtagca gccaaagact agaatccaaa tgctagcacc aattgccccg
    34021 atataggtgg acttctgtaa aaacagtgaa ataaaaacaa aggcaaaaaa ggctagggtc
    34081 aatggtgttg ttagctgata acttggcatc aaataaccat ctggcataaa gtcactggac
    34141 tgacgatatt tccaatgcgc aagcatggtc aaagcataaa tcgcaatata aacaccagat
    34201 gatgaggccg taatcagcga aaaggcatct gcaacaccgg gcaggatatt aatcaaggcc
    34261 gacaccccaa cagcaacagc agaagcaata atagccctac ttggtacccc ttgacgagat
    34321 agggtgttaa tcctcaaggc tttagtaaga gcatttgggg tctcattagc gatttgatac
    34381 aaatgccgac ctgtcgaata cagggtcgaa tttagggctg atgctgctga tgttaagacc
    34441 acaaaattaa ttaaagcagc agcccattta atcccaatca gcttaaagac catcacaaag
    34501 ggagactcgt ccgtaggcaa ctgataccaa ggcacaatcg ccataataga caccaaagca
    34561 ccaacgtaaa aaatgacaat ccgcatcgga atctcttgga tggccttggg caagaccttt
    34621 ctaggatttg cggtctctga ggttgtaata ccaacaaatt cgatggcctg ataggcaaag
    34681 aaaaccatct gaaaggccat gaaaaatttc aacttcccat tcggaaatag tgaaaaatga
    34741 tccacaatat tggcaaggct ggcatgaccg acatgcgttt caaagcccgt tagaaccata
    34801 aaaacggctg ttgcaatcaa ggctaaaatc gcaacaatct taatcatggc aaaccaaaat
    34861 tcagtctctc caaagacccg cacagcaatt aaattgatgg agctaagcaa caccaaaaaa
    34921 acgagctgaa tcagccaaga tggccaagca ggaaaccaaa actgaacata ggaggcgaca
    34981 gctgtaatct ctgccatgcc aataaagatc agggaaatcc agtaagaaag cccagaaaaa
    35041 tagccccagc ctggcccaat atattttgta atgaaattga taaaggtatg ctgatccgga
    35101 tcatagtata gcatctcacc aatagcccgc atcatcaaaa acataaagac acctgtaatc
    35161 atgtaaacaa agataataga cggacccgtt aaggcaatag aacgaccagc tcctagaaag
    35221 agacctgttc caatagtgcc tgctatcgca atgagctgaa catgtcggtt ttgcagcccc
    35281 cttaccatgc cattctcaag ttctttagtg cttttagctt cttttgtaga catttgactc
    35341 tccattcaat taaaaaaaca ccactattat atctgttttt cagaaaatgt tcaactttct
    35401 ctaaggcttg caaactaaaa aggccaacca agccttttta gcgttaacct ttttaagatg
    35461 ataggctttc aatgtaatgg tagacgcctt gaccggcaat ggcaccatct ccaactgctg
    35521 ttgtgatctg acgcagctgc ttttgacgaa catcaccgac agcaaaaata ccaggaatac
    35581 ttgtcttcat ttgatcgtct gtcacaatcc agccctcttg attggtaatg cctagctcag
    35641 ataccatttg agtaaccgga atcaagccga catagataaa gacaccacca aagtcatggc
    35701 tagtcacttg acctgttttg acattttcaa tcacaacatt agagacctta atatcgtttc
    35761 cttgaatctc cttgacaaca gaatcccaga taaaatcaag cttttcgttg gcaaaagcac
    35821 gctcctgcaa gatcttttgg gcacgcagct gatcacgacg atgcacaatc gttactttct
    35881 tagcgaactg ggtcaggtag atggcttcct caactgctga atctcctcct cctacaacta
    35941 ataactcctg attgcgaaag aaagcaccat cacagaccgc acaataagaa acacctcgac
    36001 tggtgtactc ctcttctcca gcaacaccta aaagacgatg ctttgctcct gtcgcgacaa
    36061 tcactgtttt agtatcgtag tgcgtatctt ctgtgtacac acgcttataa tcaccacaat
    36121 cctcaaccct ttgaacaatg ccataaatgt tttcaacctt aaatttttca agcggctcat
    36181 acatctttaa cgatagctct ggtcctgaaa tgtgatcata gccaggataa ttttcaatat
    36241 ctgatgtgtt attcatttga ccgccaggtg ccccctgctc aataatgcca actcgtaggt
    36301 tactacgtgc tgcatataaa gcagctgtca taccagcagg tcctgatcca ataatgagtg
    36361 tatcgtacat gggttaactc ctcttaatag tcttgtcatc attttaacaa tagctacatc
    36421 gtattgcaat tatttcgcct tcaataccac cagaatgctc ataaaggcaa aggacaaaat
    36481 cggaatcgtc aaaatagcaa ccataatcat ctcatataaa aatgcctgtc tctggagaat
    36541 ggttttatcc tttttggtca cagcacgcca taaaatccac aaaagacaaa gcatgaccat
    36601 cgtaatagct gctaacaaca gaccttccaa ataaaagcga aaaatttcta ctaacatctt
    36661 tatctacctg attaccataa ccttttttca tggcagctta gcttttaagc acatacaaga
    36721 aaagcctagc ctacctagac ctttttatta tatcaaaagc cggcttttaa atatacgttt
    36781 ttgcatagtt tgcaaaaaat tcctttgttc ttgcttcctt agggtgtcta aagatctgct
    36841 caggagctcc ctcttcaaga attttcccct tgtctaaaaa aagcacccta tctgcaacct
    36901 gataaacaaa agccatatca tgactcacta aaatcatcgt ttgacctgcc ttggcagcat
    36961 caataataga ccgttcaacc tctccaacca gctcaggatc caaggctgag gtaggctcat
    37021 ctaataatag cacatctggc ttcatggcta aagcacgcgc aatagcaacc ctttgctttt
    37081 gaccgccaga taaatgacga gggtaatggt tttcacgatc agacaagcca accttagcta
    37141 attctgctct agctatgtct gttgcttctt ggtcagacag ttttttaact atttttaatc
    37201 cttccttgac attgtcaagc gctgtgcggc gttcaaagag gttaaattgc tgaaagacca
    37261 tcgctaattt tcgtctaagc gttagaatgt cttcttttgt gatgtgttca aagtcaactg
    37321 caaagtcatc aatcgtaata cttcctgtat ctggctgttc aagataattc atgcttctaa
    37381 ggaaggttga ttttcctgca cctgatgcac caaccagagc tataacctgc cctttttcaa
    37441 tcgtcaccgt taaatcgtct aagatctttt gtccagagaa ggacttggtt aaatgagtta
    37501 ccttaatcat tagcgcaatt ctcctatctt gctattattt gttgggattg gtgctttgat
    37561 agccatgtta tattcaatta ggcgaccagc ctgttctatc aaaatactaa tgccccaata
    37621 aactaaggca actgagatgt aacgttcaaa ataacgataa tctgctcccc ctagaatctg
    37681 tgcctgtgca aacatttcaa cgatacctgc attgaaggcc agagaggttc cctttgtcag
    37741 gcctatcaac ccattaatca aggtcggtgt tgccacaaca gcggcatttg gaatgataac
    37801 tcggcgataa acctgagcag aggtcattcc taggctctta gcagcctcaa tttcgcctgt
    37861 gtgaacagat tgaatcgcag ctctaatggt ttcactcgta taagcagctt cattgaaggc
    37921 aaaggcggta atcgcaaaga tagaagccgg aatagcgttg atattccaat caaagccata
    37981 gcgttgattt aagaatttca gaaaaagagg aataccatag tagctcagca ttagctgaac
    38041 caatatgggg gttccacgca aaaagctaac aaaaaccgct tgaatcggat aaagaatgcg
    38101 aaccctgttg attttgacaa tggcaaaaac caaggccaaa aaaagaccca aggcagcacc
    38161 agctatcgtc aaaccaagtg tgattggcag acgcctgata atatctggaa tggcatcaaa
    38221 aacagcatgc cagctaaaca gcttcccttc tgggatcaac gagatgagct tgtcatacca
    38281 agcccaccca cttgttaaaa acgtagatgt catgtatcgc ccctttatac tggtttgtct
    38341 caatattttc attttaacat tcttgagatg tcatgtaaaa tagtaaatcc gcatgataat
    38401 gataagaaaa gcctatcgca gaggatagga ctcaaacaaa ggaaaaaaac tctttgaaat
    38461 accgttaaca gtagcctctt ggagctacca agcttgaact tgagccgaac tctcaaagcc
    38521 tccaagtggc taattctcaa agaatatagc cactggtaca agactaacaa tcagctacta
    38581 ggccaaaaag gtcaaaagct tggctagctg gcacagctaa ctgcctcaaa ggctaggtca
    38641 acgaaagatt gaagcctgcc cagggcttga gggcttttag ccctgtcaat taattgacct
    38701 tggagataaa gtctcctccc aaaaatgctt ggctgagctt tctgagctga cctgattttt
    38761 taagcttagc cagccttttg ttgacaaagc tctgtagagc cttacccttt tgatcattgg
    38821 caaacacata atattccaag ccatccttag cagtatcagc ctgctccttg agctttgtca
    38881 catgcacatc aaagccttgc tcctcagcta cggttgttag agaaatagcg tcatagaaaa
    38941 gaaagtccag ttgaccattc tccagcagct gcagcctttg agtaaatggg gttgactcag
    39001 aagcataggt aaggtgaata ggcttttggt caggatggga ttggttccat ttttcaagga
    39061 taagcatgta attggagcca gctattcctt gggttttctt tccagaaaga tcagctaagc
    39121 ttttatactg ctgcttaccc tttgttgcca gagcataatg cgaggccgaa atagggcttg
    39181 aaaacaaata cttttcagct ctttccttac tatagccaaa attattggcc ccaatctgat
    39241 aacgacctgc atcaatacca gccaggatcg atggaaaagg aaccacctct atgcttaacc
    39301 gatacttttt ggagccttta aaaacccttt ttagaacctc aatatcatag cctgtaacgc
    39361 tatgcttctt cctataggta aagggcttag tggcagcatc tgttgctact ctgatcacct
    39421 ctttttgacg agctgtgacc tcatggctag tcacgactgc caagagtcct agacttgcta
    39481 gcaaaaaaaa gagtgctcgc tgtaattgtt ttgtcatacc atactcctat ctcttataca
    39541 gtagccattt taacaaaaaa tgataaattt gaataatatc atttctctat caaggcaata
    39601 agaaaatagt atcaaacaag caattaaaac agcacattct tcatttacct gatcatggat
    39661 taaccacaac agacaagctt tagctattag caggctgcct aagccaaaat caacacctca
    39721 agctttcaac tgactgatgt aaaagctagt agtcacctct acaagaagaa aaagaactgt
    39781 ttgtgtcatt caaccagtag cacccttctt aactggtcat tcctatccag ctctactact
    39841 aggctgtcag ttaacgatca gaaaaaaagt tgacctatct gccttatgaa gcctagaaaa
    39901 ctagctttca ttctgtttaa cattagaaaa cgagtaaata gtttaaaata aatttttatt
    39961 attaaacttt aactgttgct atattaatct ttttacatta taattaagta taaggaggtt
    40021 ttctatgaaa aaggcaatag tatcggttac tttgttaaca gtagctgttt taagcttatc
    40081 aacaagattt atctactcca ctgattattc tgatttaaat cataaggaga tggcacgtct
    40141 tatccagtca agaaaacaac cagtaattaa gtatcatgac aatgtaacca ttaataaaat
    40201 gattacttac ctagctcagg ctaaaagaga aggcattctg acagagacct tcctcatgaa
    40261 ttatattttc gctggagagg gtgagtacct gactaaaaat tcaaggatta ttgccgatcc
    40321 tgacggaggg tattggagta tcctagaagg ttatgaggga gatggcggtg ttaagactgg
    40381 tattgacggc gtctcagagc tcaatatctt tagtccagaa tctaccagca tcggagagct
    40441 tcaagaagcg gtgctagcct ggtatgaggc taataagtaa ccgcagctta gttaaccgac
    40501 tgcttcatat aatagctaat attagctaat cataggcctt ataggcattg aaatggtcag
    40561 acccatgctc aatgcttata aggtttttta gtgcttacca tctaaccaaa accatagcct
    40621 tcagagagac attgagctga acaagcaaaa aagaggagca agctcctcct caaacattaa
    40681 tacaccttaa tctacactcc cacagaggaa gtaatttaag gctggtgtgt caaagcgtat
    40741 caacccgtta atttcaatca ctattctgac agccaaaggt gcggctttag ttgttaatag
    40801 ctggttttag ttgccacgct tcaaagatag ttgctgtaac aattgaagta ggttcgacaa
    40861 tttcaaatgt aacaatactt ttatcacacc ttttgcggga gcgtagattg aaatccttgc
    40921 acgcaacgac aggaccattt gacatgggac actgaacaga gttgaagcct ttaaaaacaa
    40981 tccctaaaca gctttgggac ctaatcacag ttccttgact cagctctgtc aaggattctg
    41041 ttcatatcag cttagaatga tcgctaaaaa ctttttgatc taatttttct tgaacggatg
    41101 atctttacca agcacctgtc ttaaaagctt tgctttctgg actgacgctc tgctcgtccc
    41161 ttggcacgtt tttctgctcg tcgctgcttg cgccgctttt catcaactgc ccattgaatt
    41221 ttctttttat agcccggttt aatttttttc ttttttttct taaccaggcc aatcatttca
    41281 gtgtctaatt tctgataagc tttttcacga ttctggcgac gatcacgatc gtaagtatcc
    41341 tgaaactcac cattttttaa aacctttggt ataaaggtaa tgcctagctt ttccagctcc
    41401 ttgatatcag aatcatcact tggctgataa aaggtaatgg ctgtccctgg caggccgttt
    41461 ctacctgtcc gccccacacg atgcacaaaa aaggataggt cttgaggaat ggcgtcgtta
    41521 atcacatgac taaccccctc aatatcaata ccacgcgccg ccaaatccgt tgccacaatg
    41581 tattcaaatg ccaggttttt gacttgattc atgatacgct tgcgctctct aggaggaata
    41641 cctccatgaa gcttggctgc cttcatacca ttagctgcta aaaaggcatg taagtcatca
    41701 gctctctcct tggtattgac aaaaagcatg gccagataag gctggatagc ctttagagtc
    41761 gccaaaattt gctcattttt atcgcgtccc ttggttgata acagccagtt gtcaatcgta
    41821 tctgcaataa cggtttctgt cttgatctgt tcaatgacag gattggtcaa atacttcctt
    41881 aaaaagggct gtagcttttg tggaatggtt gctgaaaata caagtatttg gatagtcttt
    41941 ggcagtgctg aagcaatctt atccacagtg cttaaaaagc ccatatccat tgtcatatca
    42001 gcctcatcaa caacaaaggt agaggcctta tgaatggcta aatctcctga cttgactaga
    42061 tcatagatac gacctggcgt tccaatgaca agctggggct gactaagctt taacttgtca
    42121 agctgacgct gcttgtctgt ccctccaacg taattagcaa tacgaatctc ctgcttagaa
    42181 tgcttagcaa tttgcctgct ggcctcaaaa atctgtgttg ctagttcccg gctaggtgct
    42241 gtaatcacag cttgaacctc ttctttttcc tccttgagct tttcaaaaat aggcagcaaa
    42301 aaggtatgcg tctttcctga gcctgtcttt gactcaccca ctaagtctcg tcctgtactg
    42361 acaatcggga taagacgctg ctgaacctct gttggctcta caaagccaag ctcatctagg
    42421 gcctcttgaa tataatgctt aaagtgataa tcgtgaaatg acattattta cctcgttttc
    42481 tttctgataa tactattagt gcttgagatg agcaaaaggc ggtgcctcaa gcactgcccc
    42541 agccgcttac aaataaagaa tcgctaaaac aatgagactg gctacaagac caagagccca
    42601 taggaaggca tcaaccttcc attcagacca cttggctgct ttaccggaca agccgcctaa
    42661 ttccagatga tgatgaaaag gagtcatcct aaaaatccga cggccttcac catatttttt
    42721 cttggtgtat ttaaagtaag taacctgaag catgactgag cttgtctcaa gaacatagac
    42781 aatcccaata accagcaagg tccattcctg acgaagcgca atagaaatcg ctgctagcat
    42841 tgctcctaag gctaagcttc caacatcacc cataaaaatt ttggccggct tatggttaaa
    42901 caagaaaaag gccagcaagg caccaaccat gatacctatc aagagcaaaa catcaaattg
    42961 tccctgagca taagcgataa caccataggc cagcaggcta atcacaacag ataccgaggc
    43021 cagaccatca ataccgtctg tcaggttgac cgcatttgaa aagccaacca cccaaaaaag
    43081 aacaaagcat aggtataaaa agcccaaatg ccaatgataa ccaaagacat taatcgcatc
    43141 aataccactt ggcatgacgt gtatcacata aaagaccagg cctccaacaa tctgaaacgt
    43201 gaatttttgc ttggcagtaa ggccttcatt aacctgcttg aagatcttta agaaatcatc
    43261 taaaaagcct atgatcccgt aaatcaatac aatcaacaag atccccgaaa tcaagcctag
    43321 gctttgtcca tctcgaaaat agactaaagc aaacacaaag gataagcttg tagcaacaag
    43381 aagaaaaact gttcctccca ttgtaggtgt tccagcctta gccaaatgct gcttaacgtc
    43441 ctcatgcatc tgctgccccc caattttttt caactggtaa agccttataa agtgaggcat
    43501 ggcaagggca gtcacagcaa aggctatcag acctgctaga atggttaaaa acatgttaat
    43561 ctcctaaagt tatggtaatt tttttgactt ttttgagcgc ttttccgaca tcaacgctct
    43621 gtttaacgac acgtcccgag cttgatccct tgtacttgat atcaatgcca gtccatttag
    43681 caaaggtagc cacattagcc ttagtccagc cgtacatatc aggcatctca tcaaaatgat
    43741 ttgataaaat cagaagctgt tggttagcag ctagattggt ccctgccttt ttagatacct
    43801 ttttaatctt gctgccattg ccaaggacaa tagggtgaac cagatttctg cgtagctcat
    43861 cagctgattt tcctgtatct tggccaacaa tatcaggcaa ctgataagta gcctcgtgac
    43921 tggtatctac agcaaccggc ttgtctaaag tatccttcat caaataggct tcctctaaaa
    43981 cagggttgat aatatcctgc caaaacacca ttgcccaatg ctctgggtgc ttcagtgtga
    44041 catacatcag aaaatcaggc tcatcagctg gcaccatagc aaccaccgaa taaatatagt
    44101 ttgtcaagcc accatctaaa taacctgtac cgtccttagt cgcaatctgc gcagtccctg
    44161 acttgacagc aactggtaat tgaccaacct taaccactgg acctgatgat ttcaaatgaa
    44221 gggttccaaa ttgtgggtca gtcccaacgt taatcatgta ttttcgtgtt tcactggcag
    44281 ccttttggga caccggcttt ccgacaatct ccttgtctga cacccggtaa gtatctgtat
    44341 ttgggtcata aatgcgacta acaaattgag gctctagcat cacaccgtca ttagagatgg
    44401 ctgtaaaggc tctaagcatt tgaatttgcg tcaccgaaat cccctgacca aaagcgctca
    44461 ttgcttgggt aacaatatta tcagaaggga aaatacctgg gtcttcattt tccaagccaa
    44521 agcgtgtccg gaatccaaaa cggaatttag ttaggtagtt catccatttg tcatttccca
    44581 ttttttgctc tagcttggtc atgccaacgt tacttgaaaa cgaaaagcct tgagcatagg
    44641 tcatgtactg ccctgtagaa atcccttcgt taatcgccca atcctgaatg gtagcatcag
    44701 caatggttaa gccattcgca ttgctaaagg tctcatcagg attaaagacc ttctcatcaa
    44761 tagcagctgc cagagtcata accttcatgg ttgagccggg ctcaaactgc ccctgatgga
    44821 gaatattttg ccagctatag cttttgctgt ttagcccctc caaggtgtct gcattatagg
    44881 ttggtctttg agtagtcgct aagatttcac cagtcttagc atttactaga gtagcactag
    44941 caagctctcc ttgcgccttc gactgaaaga cgtccatttg cgtttctaga aaggtttgaa
    45001 taggctctga cagggtggta taaacgtcct taccatcaac tggctttttc actgtctttc
    45061 ctgttccaag cagggtatta ccgtttctat ccttttgata agtgatgatt ccatcttccc
    45121 cagataagat gctatcaaag gccgcctcca tgcccatctt tccaactagg ctcttggtac
    45181 cgtcctcctt gttttcctca agtgaagcaa gaccaatcag ctctgaagca aaggtcccat
    45241 ttggatacat acggctagga cttgctgaaa atgcgatccc cttgatttta gctgcctcca
    45301 tagccttttg gatcgttgtc atcgtgctat aagaaatacc tgagccagac ggaccaaagg
    45361 aaacctgaaa aagacctttt tgcttaagct gcttaataac gtccttttcc tccataccca
    45421 gctgctcctt gaggatttga gcaaccttgt catactgaga cggttgaaca aaaagcttct
    45481 cgccagtcgc tgacacaaag gacttatcaa gaatggcata aatgctatag gtcgtcgagt
    45541 ccacagcgat agctgtgcca ttgcgatcat aaatcgtgcc tcgcttggcc tgaacagaaa
    45601 ccgtctcttg ataaaccttt ttggctccat ctgatagctt aacaccgaat ttctgatccg
    45661 tcccgataat gatcataaaa ttaatcataa agatgaagaa aataaagatg gttaagagca
    45721 tcatgttttg ccccaccctc aagcggttct gaacaggtgt ctttcgatca cgaaccacat
    45781 aatctaaaaa atatctttgc cattttgtca tagcttactc gaccttctta atgttatcat
    45841 ttcggttact aagccctgct ttgccagcaa tatcaacaat gcggtcacgt cgcgacagct
    45901 cattaacctc ttgcttggca ttgttaagct ctgtcctttt atctgagatc tgcctattga
    45961 gctgagtgat atgctgctgg agctgcaatt tacggctttg caggtaaata atgcttacag
    46021 ccatcgttac tgctgtcagg ataagcgtag cataaaaagc cttctcaacc ctcgagaaag
    46081 ttctaattct tttttgcaag gcttttgaaa ctgcctgagt tcttttttca ttaaccataa
    46141 tctatttccg aacttttctt gcgactcgta gcttggctga atgtgcccta ttgttagcca
    46201 ttagctcctt ttgacttggt aaaatcggct tacgcgaaac caattcaagc ttaggcttga
    46261 gctcatcagg tataaaggga agtccctttg gagcatcagc tgtgcttgct tctttaaaca
    46321 agtgctttgt cagacgatcc tccaaagaat gaaaggtaat cactgagata cggccatcaa
    46381 gggctagcag ctctatcgcc cgctggatag acgcatcagc agcaccaagc tcatcattga
    46441 cctcaatacg aatagcctga aagatttgct tggctgggtg tccttttttc ttgagctcct
    46501 tggctggctt agctgatttg atcaatgctg ccagctctgt ggtggtgctg attggcttaa
    46561 tggctctcgc ctgctcaatc ttacgagcaa tctgctttga gaacttatcc tcaccatatt
    46621 taaaaaagat ccgaactaag tcattgaaat cataggtatt gacaacctca taggctgtca
    46681 aagccgcctg gctatccatt cgcatgtcca agggagcgtc ctgcttgtaa gaaaagccac
    46741 gctctctctc atctaactgc ggactagaaa cccctaaatc atacaaaatc ccatcaatct
    46801 ctgtaacccc atgctccagc aagcgtgcct taaggtgtct aaaattgtcc ttaataaagg
    46861 tcacctgtcc cttgtcaata tagggcttga gctgctcctg cgcgtgatca atagcctttt
    46921 ggtcctgatc aaagcaatac aagtgcccct tatcaccaag cagagacagc aaataagctg
    46981 agtgcccaga gccaccaagg gtcgcatcta cataaatacc atctggctta atatccagca
    47041 tatcaacagc ttcatgaaga agtacagtta catgatgaaa ttcgtttgtc atagctctaa
    47101 ttgtaccata cttcaaaggg tttataaatc aaaaagtaag agaaaagggc tttcaaggcc
    47161 taagaaagtc cctctttatc ttactttttt tggcttagct atccttgaca tcaagatgac
    47221 taagagcttg ctgcacagcc tcatacagca gctcagccga ttcgagcacc tgcttggtct
    47281 cctttaacac ccgaaaatct gtcaccgaat tatctagcca aatatcaaag atcttatcct
    47341 gtcttgtatg agataagcta gaaggcaagc gcaactcact aaccttcagc tccttttgat
    47401 acctacagac cagatttctc acgtccccta ggctctcatt aatagcactg attttttgcc
    47461 tttttaccca gcttgttagt atcccattgt cgaacaaatc aaaaaatccc cacctcttaa
    47521 gctctttcaa tgcctcaatg acagactcaa gcttaaaagc taatgtcttt aggtctcgta
    47581 tggtttcttg cttctttaga tcccttgtca taagcctacc tccttagcag ctagctccga
    47641 atctggccat ttccattgat caggtattta ctgctggtca aggcctcaag tcccatcggg
    47701 ccacgagcat gcattttttg tgtggaaatg ccaatttctg ctcctagacc aaagacaaag
    47761 ccatctgtaa agcgtgtcga ggcattcaca taaacagctg ccgagtcaac cagatcctga
    47821 aaacgctctg cagcattgat attagctgtg atgatggctt ctgaatgatg actggtatac
    47881 tgattaatcc aagaaatagc ttcatcaaga gaggaaacca gatgaacaga catgatataa
    47941 tccaaaaatt cagccgcata atcttcctct gtggctaata cagccttgct aaacaaggct
    48001 tttgcctgct catctgctcg ccattccacc tgctgaacct tgctgatggc tgcttcaagc
    48061 atgggaataa aggtcgctcc taccttctca tgaataatca ggctttctgc agcattgcag
    48121 acgcttggtc tttgcgtctt agcattaatc acaaccttaa cagccatctc tagatcggct
    48181 gcttcatcaa cataaatgtg aacattgcca acccccgtct caatgactgg caccttagcc
    48241 ttttccttga ccgtttgaat taatctggca cccccacgag gaatcaagac atcaatataa
    48301 tccgttgcct gcatcaattc ctcagctaca gcatgagagg tatcctcaac cagcaaaaca
    48361 gcatctggcg taatagctga tgcctctaag gcatttctga taagcctgac caaggccata
    48421 ttagagtaga gagcatcttt gccacctcta agaataatgg cattattggt cttaaaggcc
    48481 aagctaaagg cgtcaacaga aacattaggg cggctttcaa aaatcatcgc aataacacct
    48541 aaaggcacac gcttttgggt tattttcagg ccgtccagat ttgtatagcc cttaatcact
    48601 tcgccaatgg gatcagccaa gtctgccacc tgtctgacgc cctgagccat cgcatggata
    48661 cgatctgctg tcaggcgtaa gcgatcgcac agaatctctg aaatcccatg ctcagccgcc
    48721 ttagccagat ccttggcatt ttctgtcaaa atcatatccg tctgggccac taattcctca
    48781 gccaaaaagg caagaaattg atttttatcc ttcgttgtca aggataccaa ggccctacta
    48841 gctgccttag ccctttgtcc tagctgttct attgtcatca cgcgtcacct ctttctatct
    48901 gtttaaacca agtgcctagc ttttctccct ccaagaccct taaaatgtct ctagggttgg
    48961 caccattcat caaaatcatt tgcccctgat gctcaaacat catctgggct gattggatct
    49021 tacttagcat accaccagtt ccaaatctgc tgcctgcacc gcctgctgag gctataatat
    49081 cctctgtaat ctctgtcaca tgactcctca agcgcgcgtc ctcatagatg gttggattct
    49141 tatcaaacaa accatcaatg tctgatagca taatcagcaa atcagccctt gtaatacgag
    49201 ctacgatagc tgataagcgg tcattgtctc caaattttgt tgaatgatcc atctcatcaa
    49261 cactaacagc atcattttcg ttgacaatgg ggacaatccc taaactaatc aggctttcaa
    49321 aggcattggt gacatttgcc agactttctg gaaaaacaac cacatcacgt gtcagcaaaa
    49381 tctgagacac tgtcgtctga tagtgggcaa aaatttgcga ataaaggctc atcatagcaa
    49441 cctgccccac acttgaaaca gcctgctgct tggcaagctg acttggtctt ttggccattt
    49501 tcaacaggtc aagcccaaag cccatggcgc cagaggaaac caaaataacc tcttttccct
    49561 tattcattaa gcttgaaatc acaaaggcta aatggtcgat cttttctaag ttaatcttcc
    49621 cattagcaag caccagcgag ctggttccaa ttttaattac aatacgcttt acatcttcaa
    49681 attgtcgttt catcatatta ggattatagc ataaaaaaca gcccagagga ctgttagatt
    49741 gaagccaaaa tcaatcagcc tatcagcttg ataaaaaaaa ggatcactgg ctacccattc
    49801 acctaagata taaaaatcca cctgatagcc actccaagca ggatttcctt tgtgacacca
    49861 cataccacgc tacgctttat cctattgtaa gtttaagtct gatcctcctg cattgtcctg
    49921 tcatttttaa tgaccatata ccaacactaa agctattgac aaaaacgcac aatacgataa
    49981 aatgaaagcg caaacagcta tatttactac ctaagggcca gaccttgctg taaagcgcaa
    50041 tacctgacag aaagaacacg tttcagaagt agcaagaaca agtcacaggc atactgtctg
    50101 gcacattggc gcaaaggcta ccagtgttca acaagactgg aacgcaaatc aataggctgg
    50161 aaatcaagta ggaaaaccgt atcatttaaa tttttggaat cccaagactc aattgttctc
    50221 aattagtttg ggggcttagg acgacagagc ctgtcagtca tctaaagcaa ttaattagtt
    50281 ataggaataa atcactatgg ttaaactatc aaaaagaagc aagatagcta tgtcattttt
    50341 aattgtcttt tgtggtatat ttttcgtcgc tcaaaaacga ttcggttcat cagaccaatc
    50401 atttaccgta aggccagacg cagatttcta tatagtcggt taccacaata ttgaaggtta
    50461 tcaattgaca aatgagcagc cgcaaaaaat ttctgacgct aagctcgaag tggtcaaagg
    50521 tcagatcaat caagtggtta aacgagcaga gctttcaaat cgttatctgg tcttttccga
    50581 ggaggggcca cctttggggg caataggaag acttatcgct cttgattttc aaaaaggcaa
    50641 cgtgacgtat cacccaacag ctgattatgc ctttacttcc tccggagtat caccagatta
    50701 ttatttcact tctacagca
//
LOCUS       DARYUW010000007        50355 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYUW010000007 DARYUW010000000
VERSION     DARYUW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50355
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(358..717)
                     /gene="rplT"
                     /locus_tag="TVW11_000356"
     CDS             complement(358..717)
                     /gene="rplT"
                     /locus_tag="TVW11_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1364494.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(778..975)
                     /gene="rpmI"
                     /locus_tag="TVW11_000357"
     CDS             complement(778..975)
                     /gene="rpmI"
                     /locus_tag="TVW11_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1364495.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(1015..1545)
                     /gene="infC"
                     /locus_tag="TVW11_000358"
     CDS             complement(1015..1545)
                     /gene="infC"
                     /locus_tag="TVW11_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1364496.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1560..1682)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1706..2386)
                     /locus_tag="TVW11_000359"
     CDS             complement(1706..2386)
                     /locus_tag="TVW11_000359"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1364497.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2401..2898)
                     /locus_tag="TVW11_000360"
     CDS             complement(2401..2898)
                     /locus_tag="TVW11_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1364498.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2947..3144
                     /locus_tag="TVW11_000361"
     CDS             2947..3144
                     /locus_tag="TVW11_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1364499.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3131..3619)
                     /locus_tag="TVW11_000362"
     CDS             complement(3131..3619)
                     /locus_tag="TVW11_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1364500.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3664..4887)
                     /gene="pepT"
                     /locus_tag="TVW11_000363"
     CDS             complement(3664..4887)
                     /gene="pepT"
                     /locus_tag="TVW11_000363"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1364501.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5057..6076)
                     /gene="galE"
                     /locus_tag="TVW11_000364"
     CDS             complement(5057..6076)
                     /gene="galE"
                     /locus_tag="TVW11_000364"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1364502.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6144..8513)
                     /locus_tag="TVW11_000365"
     CDS             complement(6144..8513)
                     /locus_tag="TVW11_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1364503.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8593..9756)
                     /locus_tag="TVW11_000366"
     CDS             complement(8593..9756)
                     /locus_tag="TVW11_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1364504.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9770..11254)
                     /locus_tag="TVW11_000367"
     CDS             complement(9770..11254)
                     /locus_tag="TVW11_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1364505.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11258..12499)
                     /locus_tag="TVW11_000368"
     CDS             complement(11258..12499)
                     /locus_tag="TVW11_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1364506.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDEKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12483..12839)
                     /locus_tag="TVW11_000369"
     CDS             complement(12483..12839)
                     /locus_tag="TVW11_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1364507.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12844..13533)
                     /locus_tag="TVW11_000370"
     CDS             complement(12844..13533)
                     /locus_tag="TVW11_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1364508.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13563..15308)
                     /locus_tag="TVW11_000371"
     CDS             complement(13563..15308)
                     /locus_tag="TVW11_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1364509.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15305..16312)
                     /locus_tag="TVW11_000372"
     CDS             complement(15305..16312)
                     /locus_tag="TVW11_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1364510.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16333..17541)
                     /locus_tag="TVW11_000373"
     CDS             complement(16333..17541)
                     /locus_tag="TVW11_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364511.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17541..18344)
                     /locus_tag="TVW11_000374"
     CDS             complement(17541..18344)
                     /locus_tag="TVW11_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364512.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18344..19279)
                     /locus_tag="TVW11_000375"
     CDS             complement(18344..19279)
                     /locus_tag="TVW11_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1364513.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19269..20423)
                     /locus_tag="TVW11_000376"
     CDS             complement(19269..20423)
                     /locus_tag="TVW11_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1364514.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20548..21396)
                     /gene="rfbD"
                     /locus_tag="TVW11_000377"
     CDS             complement(20548..21396)
                     /gene="rfbD"
                     /locus_tag="TVW11_000377"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1364515.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21538..21876)
                     /locus_tag="TVW11_000378"
     CDS             complement(21538..21876)
                     /locus_tag="TVW11_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1364516.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22174..23283)
                     /gene="rpoD"
                     /locus_tag="TVW11_000379"
     CDS             complement(22174..23283)
                     /gene="rpoD"
                     /locus_tag="TVW11_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1364517.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23292..25106)
                     /gene="dnaG"
                     /locus_tag="TVW11_000380"
     CDS             complement(23292..25106)
                     /gene="dnaG"
                     /locus_tag="TVW11_000380"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1364518.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25353..25727
                     /gene="mscL"
                     /locus_tag="TVW11_000381"
     CDS             25353..25727
                     /gene="mscL"
                     /locus_tag="TVW11_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1364519.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25953..26129)
                     /locus_tag="TVW11_000382"
     CDS             complement(25953..26129)
                     /locus_tag="TVW11_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1364520.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26284..27096)
                     /locus_tag="TVW11_000383"
     CDS             complement(26284..27096)
                     /locus_tag="TVW11_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1364521.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27164..28279)
                     /locus_tag="TVW11_000384"
     CDS             complement(27164..28279)
                     /locus_tag="TVW11_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1364522.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28549..32190)
                     /gene="addA"
                     /locus_tag="TVW11_000385"
     CDS             complement(28549..32190)
                     /gene="addA"
                     /locus_tag="TVW11_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1364523.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32180..35401)
                     /gene="rexB"
                     /locus_tag="TVW11_000386"
     CDS             complement(32180..35401)
                     /gene="rexB"
                     /locus_tag="TVW11_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1364524.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35610..37010)
                     /locus_tag="TVW11_000387"
     CDS             complement(35610..37010)
                     /locus_tag="TVW11_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1364525.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37152..39293)
                     /locus_tag="TVW11_000388"
     CDS             complement(37152..39293)
                     /locus_tag="TVW11_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364526.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39300..40733)
                     /locus_tag="TVW11_000389"
     CDS             complement(39300..40733)
                     /locus_tag="TVW11_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1364527.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40739..41416)
                     /locus_tag="TVW11_000390"
     CDS             complement(40739..41416)
                     /locus_tag="TVW11_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1364528.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLYIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41430..42125)
                     /locus_tag="TVW11_000391"
     CDS             complement(41430..42125)
                     /locus_tag="TVW11_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1364529.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42253..42888)
                     /locus_tag="TVW11_000392"
     CDS             complement(42253..42888)
                     /locus_tag="TVW11_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1364530.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42878..43417)
                     /locus_tag="TVW11_000393"
     CDS             complement(42878..43417)
                     /locus_tag="TVW11_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1364531.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(43706..47422)
                     /locus_tag="TVW11_000394"
     CDS             complement(43706..47422)
                     /locus_tag="TVW11_000394"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1364532.1"
                     /translation="MMKRLGENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            47902..48447
                     /locus_tag="TVW11_000395"
                     /pseudo
     CDS             47902..48447
                     /locus_tag="TVW11_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            48528..48983
                     /locus_tag="TVW11_000396"
     CDS             48528..48983
                     /locus_tag="TVW11_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364533.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            48983..49270
                     /locus_tag="TVW11_000397"
     CDS             48983..49270
                     /locus_tag="TVW11_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364534.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            49263..49811
                     /locus_tag="TVW11_000398"
     CDS             49263..49811
                     /locus_tag="TVW11_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1364535.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(49990..>50355)
                     /locus_tag="TVW11_000399"
     CDS             complement(49990..>50355)
                     /locus_tag="TVW11_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1364536.1"
                     /translation="PMPKPEPKPEPEAKPKPMPKPETKPEVKPEAKPMPKPEPKPEPE
                     AKPKPMPKPETKPEVKPEAKPMPKPEAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAA
                     LAVLASLGVAVVSRKRKKH"
BASE COUNT        14890 a        11522 c         9578 g        14365 t
ORIGIN      
        1 ttaaaccata tcttgtgtta aaatacaatg aaattatgac attatggctc ctaaataagt
       61 tgttttgcat tttattattt tggtgatgga tttgattaaa actagaaatc atatatctcc
      121 ttatatgatc atcacttgat ggactgctca actgtctgat acaagattaa gccctttctt
      181 cttagttaac agctaccaaa gaaaggtaaa ttggctcctt tatactaaat tagagatagc
      241 taaaaacatc tcaaatactc ttgacaaaac gtcatgactg tcttatctag ctagattagc
      301 taacataagg cattaaaaat agacttagaa ggtttctaag tctacagtcg atctctatta
      361 tttgccaagc tttgccttag cagcatcagc aagggctgta aaagctgctg catcattcac
      421 cgctaaatca gcaagcattt tacggttaac ttcgatttca gcaagcttta ggccatgcat
      481 caattgtgaa tatgacaagc cattcatacg agcagctgca ttgatacgtg tgatccatag
      541 cttacggaag tcacgttttt tctgacgacg gtcacgataa gcatagtaat aagaattcat
      601 gacctgctct tttgcagtac ggaacaagat atgttttgct ccataataac ctttagctaa
      661 tttcaaaata cgtttacgac gtttgcgtga tacaacgcca cctttaacac gtgccattaa
      721 tattctcctt caaataactc ttataattct agtaaatacc tgttacaacc cttaatctta
      781 aaggccagta accattgctt taatacgctt gaaatctcct gcatgcacca tacctgcttt
      841 acgaagatga cggcgttgct ttttagtctt tccatggaaa cggtgtgatg taaaggcacg
      901 gaagcgtttc aaaccgcctg aacctgtacg tttaaaacgt ttagctgatg cgcggtgtgt
      961 tttttgtttt ggcattttaa tattctcctc ttaacatata gtgtaatatg acaattactt
     1021 cttgtctgaa attggtgcaa gctgcataaa catttggcga ccatccattt ttgctctttg
     1081 ctcaataata gcaatatctt gagttgcctc agcaaaatca gccagtacct tagcaccaat
     1141 ctccttgtga gtaatcatac gtcctttaaa acggatagaa accttaacct tatttccctt
     1201 ttcaaggaac ttacgaccat tacgaagctt tgtttcaaag tcacccttgt cgataactgg
     1261 gctaagacgt acttccttta cagttacaac gctttgcttt ttgcgttgct ccttttgctt
     1321 tttttgatac tcaaatttga actttccata gtccataagc ttggcaacag gaggaacagc
     1381 ttgcggctgg attaaaacca aatctacatt tgcagcatca gctaaagact gagcttcaga
     1441 taatggttta atgcctaatt gttcaccttc aagaccaacg agacgaactt cgcgaacacg
     1501 aatctcatca ttaatgaata gatctttttt agctatgatc ttcacctctt tattttttta
     1561 gagaaaaacg aaagcggact taatgaacca agcccgcaca cataatatcc cgtaggaatt
     1621 tgacatgtag ggccagacaa cctaggtcgc aaggcgagaa gctctcactt ctgcttttct
     1681 cattattgac attctaacaa ataaatcatg ccatgtcaat tattttttct gctttttcct
     1741 gaataaattg gacaacagct gaaatcgtga taccggtagt atcaaagata atcgcgtcat
     1801 ctgccgcctt tagcggcgaa acttgacgat gactgtcctt ataatcgcgt gccgcaatct
     1861 cagcctttaa ggtgtcaaaa tcagctgcaa tccctttttc aatattttcc tgataacgac
     1921 gctgcgctct ttcttcaaca gaagcaatca aaaagatctt caactcggca tcaggcagca
     1981 caaccgttcc gatatcacga ccgtccatga taatagcacc agtcctagca attcgtcgct
     2041 gctgattcac cagctcctct ctaatctctg gcaaggcgga cacccaagaa acattattgg
     2101 tgacatcatt ttgcctgatc gccattgtca catcttggtc tccaagaaaa accagttgtg
     2161 agccatcagc tgctttttta aaagaaattg gacgctttgc caattcttgc aggattagat
     2221 tgacatcttc tttgtgataa ccatttttta atgcgatata agtcgctgag cgatacatgg
     2281 caccagtatc taaataggtg tagccaagat ttttggcaat aatcttggct accgtacttt
     2341 tcccacttga ggctggtcca tcaatcgcaa ttctaattgc tttcatcttt tcctctttaa
     2401 ttatttgata ttgacctcgt cacctggatt ggcataccag tagccttggg tcatatgatc
     2461 tgggtttagg gcctgtaatt gctcaacaga aattccagca cgagctgcaa tagatgttgc
     2521 tccttctcct gctaatactg taattgtctt tcctgctgcc tctgtagaag gtgctgtttc
     2581 agtcttagaa ggacttgttg tgtcactagc tgctgagcta ttagagctcg cttttggctt
     2641 tgtttttggt tttgagctga ccttctttgt tgtctttttc tgagttgatg ccccgtaaaa
     2701 tcctgttgtc tcattttgct tgttactacc gctgtttgac gtatagaaga aaataaaaag
     2761 tatggcaaca ataatgacaa agaaaacact taacaaggca gtcaaccaag gtgtgctaat
     2821 gagtgctcct cttgattttc ttgttcttgt cgccttattg tcatcaacaa ttttttcttc
     2881 ccatggttct ttagccatga ttcttccccc ttgttaattt aacaaaatca tattagaata
     2941 atacctatga aagtatctat ccttccagaa aaatgcattg cctgtggtct ttgccagacc
     3001 tactctgctc tttttgacta tcatgatgat ggtatcgtca aattggctca gtctgatgag
     3061 tcaagtcaac tcatagatcc taatgatcat gatgccatct tagcagtaaa atcctgccct
     3121 actaaagccc ttaccctcga gtaagaggct ttttttcgta ttggtaggct tcaaaataat
     3181 ccagtttaat gaagttatct agtaatataa cctctccctt aaaataagga ttaatcgcta
     3241 gatcatctaa aaaatatttt ttaggccatt ttctcatgta aaaaaggtag ctcttatcac
     3301 caacaaatag acaaaccgtt gatttagtaa cctcaatttt ggtaattgag gcaatcatca
     3361 gtctgtgcgg agcaaatagc tttaaagata cgatcttcaa gacaccatta ttctcaatta
     3421 caaaataacg atgcaggcca agtcccacta atatagcaaa taaagcaaac aagacaaaaa
     3481 cacgactcgg tatttctgtt ctttcataca ataaggacag gccaataaaa ataggcgcaa
     3541 cagcaattga ccaataaata atagaccaag acagctctgg ctgccaatga taccttactt
     3601 taccgaataa tttaatcatg cttttccatc acctccaatc cgttctgagc attttgggtg
     3661 atgttaagcc ttttggacaa tgccaagaat cacatcaact gccttttcca tcgtttgcag
     3721 actcacaaat tcaaacctgc catgcatatt ttcaccacct gcaaaaatat ttggcgttgg
     3781 aatccccata aaggaaatct ttgagccatc agtaccacca cgaatcggct cgataactgg
     3841 cttaatagct aggtcctcca taacagcctt agctagattc acaggtgtca tgtccttttc
     3901 aatcaccttt ttcatgttat agtactgatc cgtcactgtt acaaatacac gctctgctcc
     3961 aagctgacta ttcatctcct cagctagctg tgttacaaag gcctttctag cttcaaagga
     4021 gctatcctca aaatcacgaa taatataaga ggcctgtgct tcttctacag taccagacat
     4081 gctgtgtagg tggtaaaagc cttgatagcc gtccgttttt tcaggacgat cgtcaactgg
     4141 taattgacta tggaaatcca ttgctagctg cagggcatta atcatctgat ttttagctgt
     4201 accagggtga acattgcgac ctaacacctt gagctctagg gctgctgcgc taaaggtttc
     4261 atattgtagc tcgccaagcg gacctccatc aatagtatag gcaaagtcaa catcaaaagc
     4321 attaacatca aacttatctg caccaacacc aatttcttca tcaggtccaa aggcaacctt
     4381 aatgtcgcaa tgctcaatct gagggttggc aacaagaaac tcaatagccg tcatgatttc
     4441 tgcaattcca gatttatcgt cagctcctaa aagggttgtg ccatcagttg taatcagggt
     4501 ctgtcccaaa tattggttga gatttggaaa atcctctggg cataaagaat agcctgactg
     4561 accaagctta atctccccac cctggtagct ctcaataatc tgaggggcta ctccttctgc
     4621 attaaaatca gcagtatcca tatgcgcaat aaaaccaatt ttccgagtca atttgctgct
     4681 gttagctggt aagcttccaa tgaggtagcc attagctgga ttgtaatgaa tgtcctgtag
     4741 gccaatagct tccatctctg gctttagcac tgttagagca aagtcagctt gactcttggt
     4801 gcttggagtt gtagtgcttg ctggattgct ccttgtgttg atttttacat agttcagaaa
     4861 tcgttctaat aaagtttcgt atgtcataga tcacctcgat aagttttcgt tactattata
     4921 gcataaaagg acctaaaata cttgcctaag ctcagttttt tacagtgctt tatctgttct
     4981 gttacagttg cgttctcata aaaagacagc tgccaagaaa gctcttgaca gccttgatta
     5041 ttcatcagcc catgccttaa tcctcataac catttgggtg cttgctttgc catctccaag
     5101 tatctgtaca catcctttct aagccgtact ctgcagtcca gttaagctct tttttagcct
     5161 tgctagcatc agcatagcag gctgcgatgt ctccttgacg ccttggtaat atcttgtaag
     5221 gaatagacct gccaaccacc tgagaaaagg cttcgataat atctagcaca gaatagcctg
     5281 tacctgttcc taaattataa atagataggc ttggctcttc agcaaacttt gcaagcgcag
     5341 cgacgtgtcc tttagccaga tcaacaacat ggatataatc tctaacgcca gtgccgtcct
     5401 tggtctcata atcatcacca aaaacgccaa cacaatccag cttaccaaca gctacctgag
     5461 aaacataagg taataggttg ttaggtatgc ccttaggatc ctctcctaaa tcaccagact
     5521 catgagctcc gataggatta aaatacctta acaatacaat atgccactca ttatctgatg
     5581 catagaggtc cttgaaaatc tcctctagca tcagctttgt cctaccgtaa ggattggtca
     5641 ctgatagtgg aaaggtttct aaaataggaa cggtatgcgg atctccataa accgttgctg
     5701 aggagctaaa aatgatcttt ttacaattaa aggctgtcat tacctttagt agggtcaatg
     5761 tgccagagat attattgtcg tagtaatcaa gtggaatcct gcttgactct ccaacagctt
     5821 ttagccctgc aaagtgaatg acactcacaa taggatgctt actgaaaata tctgttagca
     5881 gctgttgatc gcgaatatct ccctgataaa aggtcacttc tcttccagct atcgaggcaa
     5941 cagcagctag gcttttagga tttgaattgc acaaattatc aaccacaaca acgtcatagc
     6001 cagcagctag cagttcaaca caggtgtgtg acccgatata gcctgcacca ccagtaacta
     6061 aaatacttcc taacattgat tatatacctg actttctaat aattactaat attataactg
     6121 attactccca aaaagtatat ctatcatttc attttaaaga aatcaggata ggcattaatg
     6181 tagcccttgc cttcaataag atcatattct aacagcttta agtcagaggc cacctgcttt
     6241 tgagcagcag ttagctggct gtcatcgcta tttctggtat ccaagacatc tgtcaaaaga
     6301 gcgtagtaag gagacacctt ggaatccgta tgctctagca ataaagaggt aaaatcactg
     6361 gaattaacac gaggtctagc caatttgttg gtctgatgat tgctccagat gaaataatct
     6421 gttaaatatt tgacctcctc atcattctta aagacctgat ctggataaaa gccaggtaaa
     6481 tgatcaccat aaaacacaac tgtaataggc ttgtcaacct tttccagtgc tgataaaaag
     6541 gcctttgttg acttgtcggt aatgcttaat aaattcacat aactttgcag gctatccgtc
     6601 tcagactggt ccagtcctgc taggctaaca tcaacatctc ttagctctgt gtaccaaggg
     6661 ccatgatttt gcatggtaat cactgaaaag aattgacttc ttttggggtt aagctggtct
     6721 aaaatattgt cataggttga ctcatcacta tagcttgagc tcattcgtat caagtgcttt
     6781 ggcttgtcag ctgaatcctc tgtggcaatg aaggtatcaa atcccaattt gttgtaaacg
     6841 atttttcgag agtaattgtt ggcgctcgca aggtgcaaaa caatcctatc cttaggcgaa
     6901 aaggcattac taatggcagg cgaaaacttc aacttaggaa agacatcaga atacaaaatc
     6961 gaaactgttg gattgaggtt atattttggt aggccaaata ggctttgaaa ctccatatta
     7021 gctgtaccgc cgccatagcc atcagaggtc attaggccac tcgttgtggt ttccatgata
     7081 tgatggatct ctgcaatagg atccttggcc aattgaaccc cagaaatcct agctgggtca
     7141 gcaaagctct cactcagtat ataaatcact gtttgatcag aaatacgctg atgcctttgc
     7201 ttattgatat cagcagctct agcttgatat ttctgataaa tcttttgcat agcgctcttg
     7261 ctatagcctg aaggctgatt aatggtgctg gtggtaacct gcttgaacca aacaaagctc
     7321 aaggattgaa accttgcatt ggttgtaaga ccataccagt caatatcaaa gacattgtag
     7381 actgatgaca gaactggaat accttttttg atttcaccat ctttattttg gctaaataca
     7441 aaaaggatag aggcaaatac caaaaggata gagcctattg acatcagtct aagataaagc
     7501 gctgatagga tcttttctct aaagtatctt ttatacaaaa catagatcag cagacccgac
     7561 aagactagta tcaaaataat actaatgatt tgagtcagac taatgtaatt caagaaaaac
     7621 ttaatctctt tgatccattt caaatctgaa aacaataaag gctcacttcg ctgcttgtat
     7681 ttttcaatat taacaatact gattaaagct ccgatcaccg tattgacaaa taaagcaatg
     7741 atatagttgt taatgagcaa aaacaccagc acaaaaaaga gggtcaagac aagcacctga
     7801 aacagggttg cacctggaat aatcactgcc ccatgaaaat caccatatgc tgtgatccca
     7861 gcctgaataa agtaattaaa gatgatccct aaaaataagc tggtcactag agctaatcta
     7921 agaccccatc gcttgctcaa aacctcgata aaggctgtga cgatgaggta ataaaccaca
     7981 aacgtcagca tataagagca aaagctatac ttaaagagat tcaggctaac aaggtttgac
     8041 tgactatcta aaggccaata atcattttgc ttaatcacag tcttaaataa agagctgttc
     8101 agcgttaaga ctgaaaaagc ctgactaagt aaaatgactt ggattcctct gtttgattgg
     8161 tagtccttct taaacaggta tttttttaag agaaccccta aaataagcag gctgactaaa
     8221 gctgccagac tgagtagcat ttcctgaatc gtacgattac tgatggtaaa cctgctgttg
     8281 tttttattga tggctaaggt gatatagcta ttagcaacag catagtagct actgacagct
     8341 acagaaacaa taagcagctt tgaggaagca tgcttgatca gcaaacatgc cattccagct
     8401 attaacacta agacaagcca cgaaccataa gctcccttat ttaacgtgtt tttgcttacc
     8461 gcaaaaatag ataaataaag agatgaaagg ctaaacaata tcatatcaag catttctaga
     8521 tcaactaact ggcgagcttt tgaaattatc ttcgttatta taatggtcac accctttcct
     8581 aactgctaaa agctagacat tactctctga ctcagaagcg attacctctg ttactaattg
     8641 acgaacagtg acctcccagg taaagcctga aagcacctgc tgatgaatgg cttcttgcag
     8701 gtcacaccgt ttttctttgt gctcaatcaa atgatccaac tgccttttaa tatcagagac
     8761 tgtatcatca atgatgattc cctgtgacgg gctcgttatc acttccttga caccacctct
     8821 atctgttgct aatacagcac atttcaacat acctgcctct aatacagctg tcggaagccc
     8881 ttcagcatag atggacggat taacaaaaat atcagattga gacagcaaag acatggtctc
     8941 agcaaaattc agcttgcctg taaagatgat ggactgatcc tctttatagc tatctcttag
     9001 tgaagcaagc aagggaccat ctccagcaac caccaagaca gccctgtcct tatatgtcag
     9061 ctgctcaaaa gcctccagca gcaaaagaat ccccttttcc ttgatcactc gacctgcaaa
     9121 ggtaataatg accttatcct gcaaagctgg taaataagcc tttgacttaa agacctcata
     9181 aagatcagaa tcaactgaat tgtagatgac gcctttggct tttattccaa aggtcttgag
     9241 ccatgccata ctgcgcttag acaccgcata aaagtcgggc tgataggctt tgacaaaaaa
     9301 ggtaattaca tgctcataga ctttagcaaa caagtctagt agctggtgac ctttaacatt
     9361 ttcgcccacc tgaacatagc caccaccatg ctcgatcaca atactaggga tggcttttct
     9421 tttggctagc ttcaagccca tgaggcttgt caaataaaat cgtgtattgc agatcacaaa
     9481 gtcaatacgt tcttccatca gctccgccag catgctatga tacagatcat tcttatctaa
     9541 aatcggatag cgctgcttaa atagctgctt tgaaggaaat cggtaataag taatggcttg
     9601 atctctttca atagggctca gctggtggct gttgctggtt acaatgatga tacggtagcc
     9661 taggctcact aattgttgcg ctattttttc tgtataccgc tctactcctc ctagatgagg
     9721 gcttgtaaag ccgctaaaaa tggctattgt tttcaaagct tttcccttct tatgtataat
     9781 attgcagcat tgttcgagta atcataccta ggatcaatag caacgagcca ataagaacct
     9841 gtttattact taataggcct tgggcctttt caaggtattt gttattagag gccagcaaga
     9901 ccaacactaa agggatcaca cccaaaaagt acctatcttg aacccctagc acattaaggt
     9961 ctccaactgg cgtaaaggtc aaataaaggc taaaggtaat accgcctatt attcctaaag
    10021 acatcaatcc cataccaaag cgagataagg tcggcagctg aagcttgttg gcattagtga
    10081 tgacaacagc aaaataataa accatactaa ttggcatgag ctctaccata ccgtatgata
    10141 aagggccaaa catgtaaatc cctgaaggat taaggatatg agccaacgtg tgtcttagca
    10201 gcataaagcc atatactata gggttcctta acacagtcag tagctgctct ttagcattga
    10261 ccttctggag aaagtcagcc atatccacct gaggtgactt gatttgacca tataccttta
    10321 accaaaaaac agtcacaacc agcaccgtca gaattgacaa cagctttagc agaaacgtgc
    10381 gagaggcttt tgctccaaat tgacgtgaag ggataaaaag cagcaacaaa atcaataaaa
    10441 tataaggcag cttagtaaag gtaatgattg agcacagcag ggtataccaa aagagcttgg
    10501 ataagggaat cttttcagtt gtagccatct gaacaaataa agaaatcgtc agaataatca
    10561 atccaataga gacacaatcc tgattataag aaccagcaag atagatattc atcggaagga
    10621 gacttcctac agcaagcagc tgcttgcctg ctgtcagcaa tcgtaaggca acaaaaacca
    10681 agatggcata ggcaagaaca ttacaaagcc tacctaaaag gtaagataag cccatggtca
    10741 agcctaagct ccttccaata aataagccta ttacctgtgg tatgtaggca aagttataat
    10801 agccatttgt tgagcgaatt tccttaaatg aaatagcctc atctgtatgg tctctgctcc
    10861 acagctgaaa gcgtaagggc ttgccattgt tgtggtccat aagattaatg tcatcagtca
    10921 ccagcagctt tgagtcatca ttggttaaat taagatttcc ctcagataag tataaggctc
    10981 ttgcaaagtg aaccctctca tcaggaatat cattgatcgg tgagatgaag gcagagacag
    11041 aacccataac cacaataata agcactgtcg catattccat atttgaaggt aaaaagataa
    11101 tcaaaagcgc agcaattgca actaatattg ctaaaaattt aatgggtaaa tccgttgatt
    11161 gcgtatataa aagcagcaac acaagaaagg caccaagtaa aacaagcaaa gccttactcg
    11221 ccttttgcaa tttgtcaaat aaggtatcta acatatccta tttccttttt tccataatgt
    11281 acaagccata tgacaatagc agccaaatca tcattgaaat tataaaacca taggtaactc
    11341 caatcacccc aaagcttcta gccaaagaac cagtgatggc tagtgaggag ataaaggata
    11401 caacataagg tatcacaagc aagtgctgct ttctgataat ggtaatcaaa ttatcaatat
    11461 aagtggcaaa ggtgctgata atccctccaa aaataagaag cataaaatca agctggtaat
    11521 gccttaaatc aataccataa acaagcgata gcaccggcag ccccacaaaa tagctagcaa
    11581 gcaagatagc taggcttgct aatagcagca ctagactgag acgacgctct aattgtgcaa
    11641 agctcttctc gtcctctttt gaatggtaaa tggccagctg agtgatcata ggccttaaaa
    11701 acaagaaaat caggttaatc ataaaaatag gcataaacaa aatattaaat tctgtttgaa
    11761 caccggctgg gatcagctgc tttgagtaaa gctgctccaa aacaaacttg ggctggttgt
    11821 agatataaat gagtaaaaaa ccatttaaaa agaggggaaa gctctccttc aatagcccta
    11881 agatgctttg agcatcaata cgacgctcaa ggctcgtaaa ggaaactgaa ggggttatgt
    11941 caaatagcac aatacaagcc actgaaataa gacatatcac gatcaaagac aggactagct
    12001 gcttggtcag aaccagacag agcgtaaagc caagaatcac cagcatattt cgataaaaca
    12061 aggatttgcc ggcaatatct aagcgctctc tttgttgaaa cattccttga aacacatcag
    12121 aaatggcatc tgtgcaacga tacaagcaaa tcaaccaaat cactagcccc ttaaacccac
    12181 tatagctccc caaataaata tagagcactg aaatggctat catcaagaaa caggtgacta
    12241 gtcttgtata aaaatagtct ttgaagcggt acttgtgtaa tatatccgtt gattggaaat
    12301 ttctaatctg aaataagcca atagtaatca gctgatttcc aatagcatag gcaaagctaa
    12361 aggtatctga agctgattta gataagaccc gagacacaat catcagtaaa atcactgata
    12421 ttagtgctgt cgagctggtt cccaacacat tccaaataaa aatcgactga tccgattgaa
    12481 tcctactgct ggttttcatc ttcttcctgc ttttccttct cattaagggc taaatactga
    12541 atcatttttt taagcttaat ctctgtccga gacaattttt gagtgataaa aaattggttg
    12601 atgatgagta aaaaaatgat tgatagaaaa acaaaatttg ccggcgattc aaagcctagc
    12661 agccttgaaa aataaaccgc agcatttgga aacagtgaca gcaaaagcac tattaaagag
    12721 aaaaagagcc aaaaaaagct atcttcaatt aaaattttgg atctgcgaat gctatctagt
    12781 ataaacatgg ctgtcaataa tgcaacaatg atcaaaatca gctgtaaccc aataaacatc
    12841 ctcttacctc tttctaaagt tttgaattaa aataatcgaa ataaacatgt gaaccatgta
    12901 tttaatagat ctagaaagag tgaggtagct ttgaccagcc agcctatcat tcatttgcac
    12961 ctgaacctca ctcaccctat agccttgtcg aataagataa gagatcgtat caggctctgg
    13021 agtatagtta atattagttg caaaaatcct gatcagctcc tgattaaaca ttctcatacc
    13081 agaggtcgga tcggtaatac gctttcctgt ggttagcttg ataaaaaagc taataaggct
    13141 attgcctatc attctcaagg atctattctt ttcagcactg acaaaccttg atccaatgac
    13201 acaatcagca ccagcattaa ttgaatcgct caaagcctca atatactctg gcaagtgttg
    13261 accatctgca tcgaactgga gtgctttagc atatcccttt ttaaaggcat atttaaagcc
    13321 cgtctgaata gcaccagata agccaagatt ttccggcaaa tcaatgatat tgtaatggtt
    13381 atgatgacag atctctgatg tccgatccga agagccatca ttgataatca cataatcata
    13441 ttgaggaaaa tgtcttttga tattttccac tactttttca atcgactcct cttcgttata
    13501 tgctggaatc attaccaata agtctttttt catatcgtca aatattctct ctattcattc
    13561 gtctaaacgc gtctttttag caatcgcttt atgatataac ggatagcctt agctggccca
    13621 atcacaatat attttaaggc tccttttata cctcccatat agtcaaaatc gacataggta
    13681 tgtggcacac tgccttcacg caggtttaag agcttattat caataaatgg tgtcaatagc
    13741 ttttcatttc ttgaaattct aaaatcatag tgtctgtccc aagcaatata aattaagaga
    13801 cgttcaatgg catgcaggat cgaattttga gacagaggct ctgctggaat atcagcctca
    13861 cttaggtcta agtcaaacaa gggctttaag gcatcgtatt taaaccaaac aaaggtgcca
    13921 tagctcatga caaaggtatc catcgtctga aaatcaatgc gttttgtaag ccccattgcc
    13981 tgccaaagct gattcatttc aggggcaata aggtgctcat tccaagcgtc aacaatttta
    14041 ttaaaacgga aaaaacttgg aatatctgct atcacaatac cgatagcatc agcagccagt
    14101 gctgttagga tttgatccgc cggcttcacc atcatatcaa tcaattcagt gcgccaggat
    14161 tggcccgccc aaaaatctgc ttcctttgat tttttggtat gaaaatgccc aatataatca
    14221 tattgagaca atcgttcctt taaggtcagc attggcaaga catctcgacc gatatttcct
    14281 gtcaccaata tgtcagcact tgccccgctt tctcgtagaa tttctttaat ctcagccttt
    14341 ttagccttgc tatcggtcgt tatgagcaag tcataatcaa aatgaaaatg actaaatgct
    14401 tctaaaaact ctgacaataa atcaacataa aaaacatgaa gatgaacagc aattttcttg
    14461 ctttgatcaa tgcttatcgg ctgctctggc aggtatttat gtgccagaag atacttagca
    14521 tctggtggat ggacctgcga catatgatcc acaatcaagc tggcagggta tgtcgttttt
    14581 tggtcaataa aatccaaaag gtaaggagca atgtgctggt tagcgtcaat agccttaacc
    14641 ttgataaagg gcacatggtg ctttaagatg gctgtcggat tgtaataaga gaaatccgca
    14701 tgcagcatag aggacgagtc ctccttggtc gtatcaaata ccgtcttgta tcgaaagcca
    14761 gcctccacaa agacagtggt tattctggtt tcataattgt ggatcacatc ttgaacgtct
    14821 gttagctcaa cgatattttc ccaaaactgc ctaaattcct tactatgaac gagggatttt
    14881 ttgaagctga taaaatagct ctgaatatgc tctttaaagg ccttggtcgc tcgattgttg
    14941 gtcatgcccc agaaatcaac tgcttcatct gcttcatatt tgagataata aggcttcata
    15001 tcccaaagcg gaccaaagca ggtatcgttc ataatcgtga ttgagtcaaa gtcaacaagg
    15061 tgctcacagc ctaaggcctt cataccatca tgccaagctg caaaatcata gcctttattg
    15121 tgtcgttgaa taaactgatc catcaaatgc cgctgttcaa gctgctcaag gtcctcttga
    15181 tggatatcac tatttgaaat aaagacaatc tttgaaaaca aggctctcat ctgttcgagc
    15241 tggtaataaa catgatcgct taccttatga tatttattga aatgcacata caataataga
    15301 cgcttcattt tttcctccta aaaagctcaa gcagctttga taggtacctc caacgacgtg
    15361 aggtaaccac acaattgtat tgatgggtta gcgcttcaac ctcttgcctt tgatgatcaa
    15421 gctgctgctg tagctgatct atcttctctg cctgtagagc ctcctgatct gcaagcgtct
    15481 gtcgtaattg atgaatggta tgacttaatt gatgaatccg aatttcattt ttagcgtcct
    15541 gctttagtaa tgcttttgca atagcttcca tattggctgt agggtattta gacaaatagg
    15601 acagctgggt ctccaacaag ccttgaatac ggcccagcat tttttcctct gctgccggcc
    15661 ttgaatctga attatccgtc attcgataaa cagtggtcga atccttcaaa taggctagag
    15721 aggttgactg aaacagctct aattgtatgt caaaagtgtc gtctgacgtc tccaaatcaa
    15781 tgcgttgatt aactgccctc atcagatcag cctccaccag ccaggttgat gacatggtca
    15841 ttccttttaa agcaagcatt ttctcgtagg tgtctgttaa gggagtaaag ccactttcaa
    15901 aggcattgct ctgaataagc ttgccgtcag tatctacaaa atcaaagtca gtattagacc
    15961 attttgaatc tggtgagcta tccagcaaat caacctgctt ttgtagcttg agagtatcag
    16021 tccaatagtc atcaccatca catctggcaa tatactgtcc ctttgcctcc aaacaagcct
    16081 tgacccaggt tcttgcaatc ccaagattta cctcattaac gatgagtcgt atacgatctg
    16141 gaaagctggc ttgatagtcc atgaggatct gtctggaata gtctgttgaa gcgtcgtcaa
    16201 tgacaataat ttcaacatca aagctggtct gttgggctaa aaagctgtct aaggcctctg
    16261 aaatccaagg ccccttatta taattggtgc aaataataga aacttttttc ataggatgct
    16321 ttctaatgac aattattgat taatgagcca gctaccattt ctttgatata agccactggc
    16381 agagtccaaa gcagacaggt catctggagc aatatcgttt cgttgaagca cgactaatgg
    16441 ggaatgatta gctgttaaaa agagcagcat ttgcccgttt tgatcgcgaa cagtcacctc
    16501 aagctttaat ttgatatcat ttaggtgtga gagctgacac tggtaggata tgttcttatg
    16561 accaggacca cttgtcggtt gatcctgtga attgtcatta tatacccaaa tattgcggtc
    16621 aatatcagtc aacgaaaagg caacataggt aggctcgtcc tttaagacat gataggaaat
    16681 ctcaaaggaa atgggctcat ctggactaag gcttggctta gaggtcaacc tcacctctaa
    16741 ctggcttgcc aaatcagaca caggctcagc agcagctcct tgctcagcat ttttcaattc
    16801 agtattatca acactgtatt ggttagcgac atcaaagggt tcgccgtaag ccttgacaag
    16861 gccattttcg atgaggactg cgcgattgca gtattttttg acagccccca tatcatgggt
    16921 cactagtata gtagtcttgc cgctctcctt gcgctccatg aagtagtcat tgcattttcg
    16981 ttgaaaggcc tcatcaccaa cagctaacac ctcatcaaga atcagcacat ctccctgtgc
    17041 cttgatagcg acagaaaaag caagacgaac ctgcatgcct gaggaataat tttttaattt
    17101 ttgattcatg aaatcatgca gctcagcaaa gtcaacgata tcatcataca tatcatcaac
    17161 ctcttctgtg gtaaagccca gcattgcgcc attcatgtag acattttcac gcccagtcaa
    17221 ctcaggatta aagccaacac caagctcgat gaaggacacc attttcccct caactgtgac
    17281 ctgtcctttt tctggaacat aaatttgaga aataattttt aataaggttg attttccaga
    17341 gccatttcgt ccaacgatgc caaaaaaatc ccccttatac acgtcaaagc taatatccct
    17401 tagcacatgc tgctcggtat agcccttaat gcctttaaaa cggttaacaa gagcagtacg
    17461 aaagctcttg gttgcctctg ttggcagctt aaaggactta ctgacatgat caactgttac
    17521 tgcaatttct ttattagcca ttagataatc tccgcaaact tcttagcatt tttattaaac
    17581 actgctaccc caagtgctaa taggacaaat ggaatgaggt aaggaatgat gatatagcac
    17641 caatttgtcg acatttgcca aatggtcaca ttagctctgt caatcagcag ataccgcaaa
    17701 tcttgaataa tctgtgctaa aggattaagc atcaaaatct tggcagcaag agggtgtcgg
    17761 tcaaacacaa aggtaatcgg gtagatgatg ggagtcacat acatacctgc ctgcaataga
    17821 acctcccaaa cctgagccaa atcacgataa taaacaaaga cggtagaaag catcaaggcc
    17881 acaccaactg taagaacagc cagctcaaca aagagtggta aggccagata agcgtgagga
    17941 gataaagtaa ctccattgat agctgcaaaa accaaaacca ctaataggtt gattgaaaag
    18001 ttaatcaatg ctcctaaaac tgctgaaaaa acgatagtat gctttgaaaa attcaatttt
    18061 ctaagcaggt ctcctcgcga tacaatagag accattccca tactggttgc ttctgagaaa
    18121 aaggaccaaa tcacattggc aagtaaaaga gcaaccggaa aatgaggaac gtcaccacca
    18181 gttcgcaaaa acctgataaa caccaaatac atgatggtaa acatcatcaa aggctttaag
    18241 atagaccaca aataaccaat agcactgccc tgatacctta gtttaaagtc tgttttaaca
    18301 agctctttca aaagaatacg attcttttta ctcaataatt ccattattct tttctcctat
    18361 agccaaattt ggtcatgatc aatgccataa aaacaagggt atgaaaggca cgatttttcc
    18421 gaaagccata cgctttgaaa tcagacagac gctgatagaa aggcctatcc aaaagcccta
    18481 cgtaagcctc aatcaatctt ctgtcagccg gatttagctg caagtctagc aattgccttg
    18541 cttgatgttg actagaaaca ataagccacc aatacttctc tatgagctta tggggcttac
    18601 gccactgctt cagtcgctta gaccaggttc ttgcccctaa aacattagca tcatgctgac
    18661 gatagagctc tgttgccaca tctagataca caagctctcc ctgcgctgct gcaatcaagg
    18721 ctaaatacca atcatgcatc accacatgct cacagctcac ccactgctct gccagcgcgt
    18781 gattaatcat catagtgccg cctgtgactg tgttttcagt caactcctgg actagctgag
    18841 tattagcatg atgtgattgt gtttggatca tactctcatg acgtacttct aagtcttgat
    18901 tgaccacctt taggtctgtg tagactagta agggctcgct tatcttgtgc ttttgcgctt
    18961 ctgccagagt aagctctaat ttattgtcta accacacatc gtcttggtca ctgaaaaaat
    19021 aaatatctgc cttttcatat gttaaaaggg tgtgaaagct tcgaatcaca ccgaggtttt
    19081 cctgcacatc agcattaatc aagcaaattc tcggatcctt tttagcaaaa gcctgaatga
    19141 tggcaagcgt tttatcagta gagccatcat ctctgactaa taaggtccaa tcctgcaccg
    19201 tctgcctttg aatgctttgt atttgctctg ctaaaaaccg cgccccgttg taggtagaca
    19261 ttaaaatatt aatcttcatc taaaaataag gcctcatact ctcctacaat tttctcccag
    19321 gtatattctt tggcaatgat ttgcttagct ctttctccca aatcagcaaa cgattccttt
    19381 tgatcaaccc tgttaatcag tccagtaagg ctgccctttt cttttgtcca ataaagggct
    19441 gctgttttag caactgattg attaaaggtc actcccaaaa ccaaattaag ctgggtatgg
    19501 gctagggcct ccaaaagacc tggattggta cctccaacct catgcccatg aatataagca
    19561 aaagcatgct cacgaatata agctaaaagc tgcttatcat actgtgttcc aacaaatttt
    19621 acacgcgcgt ccttatcaca gccagttgca ctaaccagcc gctcaaaata aggatttttg
    19681 tcatggttgc aaataataac caaatcccgc tgagtagatg atgccataaa ctctctaatg
    19741 gctgtttcat agttgttttc aggaacaaag cgccccaaaa tcaaatagta ttggttttct
    19801 gttatctcaa atgtttgaaa gtaagttctg actttttcat ctgatgtaga caaacaagac
    19861 cgccctattt ctgtcccata ggcaataaaa gtcgtttttg cccaaggata agactttttg
    19921 atgtaggctt caatgccaat attatctgag atgaccaaat cagcatgctt tgtcatttgc
    19981 ttttcggcgt atttcaggta ttgctgaaca ggcttagacc attttgaacg cttccattcc
    20041 agcccatcag gattaatcaa caaacgccca ccacgctggt gaatctgctt tgcaaagggg
    20101 gcaataaagc ctccaatggt attgcctaga acataaaaaa taggcttttg aatatgatac
    20161 ctatcaatat aagctaaagc gtgactaata gccatcatat cataagcaat cactctagct
    20221 ggaccgagct taggaggatt gatataaaaa caatctgctc ccttgtacac aaaatgctcc
    20281 ttgtgcttgc tatcgctcaa gcaggcaata tgataggtaa tgcttttgtt ggtctgatta
    20341 gtgactaatt cttcaacaaa ggtctcaaaa ccaccatact tcgctggtaa accgcgactt
    20401 ccgatgatga aaacatcctg catagcacac tgccccattc taaaatataa ttagtagtat
    20461 tataccatat aaacaggtct tatgcgacat aaaatccatg aaaagagagc caatctccta
    20521 gatcagctct ttagtgctat cgcttattca ttgctgttgc ttgtaaaaag cctccagggc
    20581 ttcttgccag gtaggaatca caaaaccagt tgccttagcc ttatcaagat tcatggttga
    20641 gttaaagggt cttttggctt tagcaggaaa agccgatgaa tccacaggca caacctcgac
    20701 agctgtctct tttaagattt ctctagcaaa atcataccaa gtggtgtctt ctttagcatc
    20761 atttgacaaa tgataatagc cataaggctt gcgattgtct gctagatgac acataaactc
    20821 agccaaggtc ctcgtccagg ttggacgccc atgctgatca ttgacgactg tcaagcgaga
    20881 gtgggtctta gcaaggtttt gcatggtaaa cacaaaattc ttgccataat gaccaaacac
    20941 ccatgcggta cgaataatgt aaaattgctt ggtatatcgc tcaacagcca gctcacctaa
    21001 gcgcttagca cgaccgtatg ctgtttgagg atcaggagta tctgtttcta gccattcctg
    21061 accagctggc ttttgaccat caaaaacgta atccgttgaa atataaacca aggtcgcccc
    21121 gtagcgctca caagccttgg caatatgctc agtaccagct acattgatag cttcattcag
    21181 tgcttttcct tcttcttcag cagcatcaac tgctgtgtag gctgcacagt gatacactaa
    21241 gctaggcttg acctgagcaa aaacctcctc tactttagtc gcgttggtaa tatccatttc
    21301 agcaacatca acagcaacat aatcgacgct tcgttcgtct aaaagataac gaagctctgt
    21361 tcctaattga ccattacttc ctgtaattaa aatcatcttt tctcctttgt aaaggtctta
    21421 tttctttgag ctaatcacgc agctcactcc catctaatcc taagagaggc ttttttgatc
    21481 agctgaccct agcaagacct ttgttgtggt atcgtatcag ccttgctttt tatctagcta
    21541 ccgaatacct agggcaattc tcgcatagcg gctcatcttt tcaacgctcc aaacagggta
    21601 ccagaccaac tttacctcaa ccttggtcac ctctggaaca tctctcatcg catcatgaat
    21661 atgatcagtc aacaaatccg ccaaaggaca gcccattgtg gtcaaggtca tgtcaatctc
    21721 ggtatgacca ttgtcatcaa aacgaatctc atagaccaag cctagattca caatatcaat
    21781 acctagctcc ggatcaataa ccgttcccaa agcttcaaga atccgatcct tgatagctgc
    21841 aacctgctct tctgtgtatt ttaatgtttc agtcatagct attcctttca cttttttcga
    21901 agacctgata tgatgccaag tcaaaaacca gcccaaagac cagcgcattc agcataccta
    21961 tgatgcccta agctgactaa cattgatagc ctctttttag tcacccttac attaacacta
    22021 gtctttagct actggctagc aaaggtaatc tcataaacca gtaactaggc ttggagtcgt
    22081 tgaccatagg ccactcaccg tcaaggagag ataacgcatt tcgggctcgt ctcctatttt
    22141 tagctcgccg ttaaaaaggt ccaccggacc tttttaatcc tcaatgaagt ctctgagctg
    22201 cttgctgcgg cttgggtggc ggagcttacg caaagcctta gcctcaattt gacgaatccg
    22261 ttcacgagtg acattgaaga ccttcccaac gtcctctaat gtacgcattt tcccatcatc
    22321 aagcccaaag cgcaggcgaa gaacattttc ctcacgatct gtcagcgtat caagcacttc
    22381 gtctaattgc tcacgaagaa ccacacgagt tgtgtaatca acaggatttt caatcacttc
    22441 atcttcaata aaatcaccta aatgactgtc atcctcttca ccgattggtg tttcaagaga
    22501 cactggctcc tgagcgattt tcagaatttc acgcacctta tcaggggtca tctccatacg
    22561 ctctgcgatc tgctctggag taggatcctg ccccaattct tgaaggaggt tgcgctgctc
    22621 acgcactagt ttattaatgg tttccaccat atgcacagga atccgaatgg tacgtgcctg
    22681 atctgcaata gcacgagtaa tggcctgacg aatccaccag gtcgcatagg tcgaaaactt
    22741 gaagccctta gaataatcaa acttgtcaac agccttcatt aagcccatgt taccttcttg
    22801 aatcaaatca agaaattgca tgccacgccc tacataacgc tttgcaatcg acaccaccaa
    22861 acgcagattg gcctcagcaa gacgctgctt agcctccata tcaccagcgg ctactgcaac
    22921 cgctaaaacc ttttcctcat cacttgtcag cagcggcacc acaccgatct ccttgagata
    22981 catgcgcaca ggatcgttga ccttggctga attacttccg ataagctcct cgtctgtcag
    23041 ctcctctggc ttaggctctt caacgacgta tttagatgag ggatttcctt ccttatctgt
    23101 aatggaaatg ccaccatctg tcaaacgctc aagcaaatca tcaatttggt cagcatctaa
    23161 ggtaaatgga atcacgagtt tttctgtgac ctcatcatca gtagctgttc cttccttttt
    23221 atgatgacga ataaactccg caatttgaac gttaaaggtt gtaatttctt tttcttttgc
    23281 catattttcc tctattccat ttttcttttt tcagcaatga aacgctctaa agcctctaga
    23341 gccatctggt ggtcaccctt actgctagat tccctaatct gctttccttg cctatgcagc
    23401 tctctttgct ttagcaatgt catttgcctt gataaaatat cctcaatctc accgctagct
    23461 atctcatcag gaagattttc ctctaaaacc cggtaatagg cttggttaac ctcttcagac
    23521 agttgcgata ggtcatagga ggtaatctgc cctgtggcct ttagctgctc atacagcgtc
    23581 tgaagggctg gtgtatcaaa ataaaaatcc ggccgatgac gaaattcatt gagcaaatag
    23641 tcgtgatgaa gcaggcgatg caggaggtga ctttctgttt tagccaaggc tgtcatgctt
    23701 ttgttaatcg gtaaggtcac cagagatgcc tttggttgac tagcctgtcc ttgttgtaag
    23761 ctttgcctat cttgtagcct taaagcattt accgattgct ccacctgaaa ataatcaaaa
    23821 tccggcagca aatcagccac cttattaata tacgaatttt gtgcggtgat tgagggtgct
    23881 tgagcaataa tctgtgatat atgctccaca taagcaatct gcgattgcag gttatccata
    23941 ttttcaggct tcaggtgatc aatcaaaaac tcaacactgc taatgcgcga gtgctggagc
    24001 aattctgcta gagcctctgg tgaatgctgc tgaacaaatt catcgggatc cattctattt
    24061 ggtattttca cgatctccac ttgaaaatct gccagcagct caagagactt ggcaatagca
    24121 ttttgcccgg cgtcgtcacc atcataagtc aatacaacct tttgtgtcag ctgcttgagg
    24181 tgcctaacat gctctggcgt caaggctgtc cccatagagg caacagtatt accatagcct
    24241 gcccggtagg ctgcaataac gtccataaag ccttccatca aaaagacctc atgagtctta
    24301 gcgattatcg gcttggcctt atcaaggtgg taaagctcat aggacttgtt aaataggacc
    24361 gtagcccttg aatttttata cttggcctgc tgcttttcta tatcctctct tgcccagata
    24421 cgtcctgaaa aagcaatcat attgccctta tcatcacata agggaaacat gattcgatga
    24481 cgaaaggcat cataaatagc atttgattgt tcagaaacat gaaacaagcc tgaggctgtt
    24541 aattgcgcct cagtatactt ttttgacaag gcttgataaa ggtagtccat ctcgttaggc
    24601 gccaagccaa tccgaaaata ctctattagc tgatcatcaa gccctctttg ataaagatac
    24661 tccttggctc tttggccaat ctttgtcgtc atcaaaaccg catggtaaaa cttagcagca
    24721 tcttcatgaa gatcaattaa agcctgatga gggtgctgct tttgactcaa actagtctga
    24781 cttggagcaa cagtaactgc cataccagcc ttatcagcca caatctgaac actttctaaa
    24841 aaaggaacct gccgatattc ctcaataaac ttaaaaacat cccccgactt accgcagcca
    24901 aagcagtgaa agaactgtct atcttcgatg acattaaaag agggtgtttt ttctttatga
    24961 aagggacaca atccaaggta gtgccgacca gcccgcgata gatggacaac ttctccaata
    25021 acatcaacaa tattgacatt atgcttgatc tgagaaatca tctctttgtc aatagccaaa
    25081 ccgtcacctc cccacaaaaa gcccattgta aatttacatt tcattatacc attgaaaatg
    25141 agctttgtaa attgtaaaag cacaatcctt catcatctaa agcccgctac atcaagcaat
    25201 aagctatgct aaagtattga cgtctcttat gatcactagc ttgactagca gtacagcatt
    25261 aagtagctca tcagtccttg ataagctctt ctattagcct ttttgaccta tttgtgctat
    25321 gataagatta tctgaaaaaa ggggagtcaa tcatgctcaa agaattaaaa gcatttttat
    25381 ttagagggaa tattatcgac ctagcagttg cggtgattgt tgggagcgcc tttagcgcta
    25441 ttgtcacatc atttgtcaac gacattatca caccgctgat cctaaaccca gccttgaaag
    25501 ctgcaaatgt ggaaaacatt gctcagctcg cctggaatgg catcaaatat ggcagctttc
    25561 tcagtgctat tatcaacttt ttaattgttg gtaccagcct tttctttgtg gttaaggtcg
    25621 ctcaaaaagc aatgcctaaa aagggagagg aagagcccgc taagcccaaa acaccaactc
    25681 aggaagaatt attacttgac atacgtgatt tgttagccaa aaaataactc aaagctctta
    25741 cagcagctgg acctgtccgg ctgctttttg atatacaagc acagagcact tagcgatcaa
    25801 aagataatag aaccggctct atttgctgtt ttagcatatc attgctattt ttatcagcag
    25861 caagctaagg taaaaaaaga caaactagta tcctcatact ggtttgcctt caaactaagg
    25921 cagcctacaa agggccgcct tttttatgat gattagaatt ttttacgttt gcgagctgct
    25981 tctgatttgc gtttacgctt tacagaaggt ttttcgtaga attcacgctt gcgtgattct
    26041 tgaagagtac cagctttagt aacagaacgt ttgaaacgac gaagagcatc atcaagcgat
    26101 tcattcttac gtactactgt ttttgacata tgtttcacct cctcaagata ttgtaacatt
    26161 ttcacgttct agcttatctt acatgatttt tcggaaaaag tcaatgatct tttcttgatt
    26221 ttgaggtcat tcttaaaaaa ataccttaaa atttgctgct gcattaggca tcacttggca
    26281 aggctattct actgcatttc ctgttaataa tgctgcttct tgaataaagg ccttgtattt
    26341 gccatccttg tttaattgct tgatcacctt attaatggtt tgccttaggt catcactccc
    26401 ctttggcata gctacagcct tagcatctcc atcacttgcc tgcaatttaa atggtgctaa
    26461 agccaggtct ttatgttgag ctaaaaagcc tgcagctact ggtgcttcca aatcaacagc
    26521 ctgcacctgc ccagatttca actcattaat agcctcaccc atcacagtta gagaaacaca
    26581 gttggcttta ttaagctgct ccttgactag gccctcctcg atgctgcctt tttgaacagc
    26641 cacctttttg ccaactaagc tatccttatt agcataatgc ttggcatctg acgctttcac
    26701 caaaatagca ttttcagttt catagtaagc ctcagaaaaa tcatacactt tggcacgctc
    26761 tttggtgtag gacaaaccag aaatcgctat atccacctta ccagtttgca gactggataa
    26821 gacattatca aaattcatag cagagagttc aagcttaacc cctagttcat cagcaatggc
    26881 ctgtgccagc tcaatgtctg ctccgacaat agtatccttg ccgtcaacca aggccttaaa
    26941 ttcaaaagga gcatagtcag ggctaacagc aaccaccagc tttccctttt cctggatcct
    27001 gtcttgaagg ctcgtcttgt tagcttggcc acaagctgcc aaagcaaaaa cagataccat
    27061 agcaagtgct ccaactaata atcgcttcat gttcatatta taattattcc ttttcttgtt
    27121 gatgaatctt attatattgc attattattc aatggtcaag tttttattga atatttttca
    27181 agcactgcga tagtctgctt aatcctgcct gtagaacctg cggctgacag caatagccga
    27241 ttctcacatg atttgcttga ttaaagcgat ttcccggaac gaccaaggta ccgtaatcct
    27301 ccagcagcct caaagcaaag gcttccatgt cctcatctat atctagccta acaaaggccg
    27361 ttgagacctc attcggtcta tggtaggagg ccctggcttc acctgttatc cagtcctcta
    27421 agatagcaag gttagtcctg ataatggctt gattgcgctg caatagcttg tcagcatgct
    27481 tcaaggctag cgaagccacc atatcatcaa aaacacctgc acagatcatt gtgtaatctc
    27541 gatataacct aagctgatca cagatggtct cagaagcggc tacccagcca actcgaatgc
    27601 ccggaatcga aaaggttttt gacatgctat taacagtaat ccccttatca tacaaatctg
    27661 ccaccgctaa aagatgatca gaggtaaagg aatgataaac ctcatcactt agcaggtaaa
    27721 tatcatgctc tctagcaata ttgatgagct cctctaaata aggcttggtc atataggcac
    27781 ctgttgggtt gttggcattg ttgatcatga tcatttttgt gttgggacga atcatggcac
    27841 ctagctcatt aaggtctggc agccaagcct gctcctctct gatctgccaa taatcaacct
    27901 ccactccaag agaagctgga atatcatata gctgctgata gctaggatag tgagcaatca
    27961 catgatcacc tgcttcaagc agtgcataaa taaccaaaaa attggcacct gttgccccat
    28021 tggtttgcaa gatatttcta gctttctgct gctgataaag ccctgccact gcctgcttaa
    28081 agtcaggaga gccttctatc cagccatagt ctaatggctt ttgatgcagc tgctggtaaa
    28141 aggcttgagg ctgctcctgt gttaagtcaa agagctcctc aagcgttaat gaagcaatag
    28201 atgagccagc aatatcgtat acagcacgtt tttcatgctg atttagccac tcttctacac
    28261 caaataccgg tagtttcata agatcacctt atttcttgcg taatatttat tacaatatcg
    28321 cataaaaata caattgtcaa atcaaaaact atcctttttt tgataagaat catgtcctat
    28381 ctaacagtta gtcctgattg gtctcgcatg aaaggctact aaatagagca aaaatcacat
    28441 aaaaagactc ccaacccacc aatcagcggg attaggagcc tgatagctcg tatcaattca
    28501 ttgatttcag atcagagtga ctatcatcac tctactatga gccaatgact aggctaggcg
    28561 gacaacttct agctgtgatc cacccattaa taccaagtat ttttcgatcc ttgcaatccc
    28621 gtaggattgg ctcagagcct cggcatatag gtccatttgc tgctgatagc gctgcttcag
    28681 ctcagctgac tgctgatagc gatctgtctt atagtcaaaa agaacaatac gatcctcaaa
    28741 aagcaggtag ccatcaataa taccacgcac tacgtactgc tcctgactta ggctgtcttt
    28801 tttcagcatc gcaaaaggag cctcgcggtg taggcgctgg tgatgctctt gcaggagctg
    28861 ccccaattca gttgtcgcaa aaaaagaggt taccttttca atgtcaagcc ttgccttgac
    28921 ctctgcgtca gctgagacaa gctgtaaggt ctgttcaata tcaccagcag taacctgatc
    28981 agacattgga atacgctgca tgagctcatg caggcttgag ccgacctggc taggctcaac
    29041 agcctttttc ttagaaaaat caggaagctc aaaggtcttg ggcctatgat aaggctgatc
    29101 tatgatatca acaccatcag tatccattag aggctcataa agggttttaa gctgactggg
    29161 ggttctcacc gtcggcagct caatggccgc ctgatagctt gcattgagct ctgacacctt
    29221 atccagcatg tctaaggcac gcgcaatgtc ctctgtttga cggttatcct tgagatcatc
    29281 tgcttgcagc agccctgagg gccttagctg accaacagct tctggtgtta agtcactgtc
    29341 atcaacaaat cgcacatcaa taaacaagtc ctccttgcta aatgttgctg ctatcgctag
    29401 tagccagtct tgaaagctca gcaatctttc tcgactagct aaggctaagc gtccttcgga
    29461 gctattgtcg gctgtttttt cctgtacctt ttccttgcta gccttaccaa tgaggtatac
    29521 ctttttttct gctcgcgtca tggccacata caagagacgc atttgctctg ataaggtcgc
    29581 caagcgtagc tgctgcttat tgagctggta aggaagagtt tccatcgtaa ccttgagcga
    29641 cgccaatttt tcttctctta gaagctcctt tacattggcg acatatttga taccgattcc
    29701 ctcatctcta tttagaatga ttggcgcctg taggtcagcc atcgcaaagc gcttgtcgca
    29761 attcaaaatg aacacgtaat gaaattcaag tccctttgat ttatgaattg tcatgaggtt
    29821 aacagcatgc ttaggccttt cgacctcaac atctgccaaa tcattttgcg tctccagcac
    29881 cttatcaatc atgccaataa agcgtgagag tcccttgtag cctgattgct caaattggtc
    29941 agcccgtata gcaagggcgt aaaggtttgc ctgagcctgc tctgcctttg gctggcttgc
    30001 tacaaagtca aagtaaaagc gatcgttaaa aatcttccaa atcagctcat aaagcgaatg
    30061 aagctttgca aattgacgcc agtctctcaa ggtcccatca aaatcagcca gctttgtcat
    30121 cagctcctga ccgatcagct ctgggtgctc gccttgtcct ctcaagctat tgctaagctt
    30181 gtcatagaag gcttgaggct gcttttgtga gctgccttgc agtgagattc ttgccagctg
    30241 atcctcatca aaggaaaaca ttggcgagcg cattaaggcc actagggcat aatcattcaa
    30301 aggattgttg atgcttctta gcgtatccag catgaccatc acctcaactg atttgaggta
    30361 attttcttgg ccaccatcag caacgagagg aatgccatac tgattaaaga cctgaaaaat
    30421 agtgtcattt cgtgtgcgtg acgaaacaag cagggtaata tcttcaaaag caaccttctc
    30481 ctcgttatag agcctgatga tttccttagc cactaagatg acctcacctg cggagatacc
    30541 atcgttagct aaggcttcct cggtgccttc ttgaacttga tcggtgtcat agagcagcaa
    30601 ttgggctcga ttgttaggat atggctgtct ttgtccctca ctgcctgcta ccagctggtg
    30661 cttgtcatca taggtaatct ctcctaaaga ctcgtccata aggcggctaa agacagcgtt
    30721 ggtgacattt aggacctctg actgactgcg gaaattttcc tttagtaaaa tcagcttgcc
    30781 atgctcggga ttgctttgat aatccttaaa cttttgattg aagatttgag gatctgcttg
    30841 cctaaagcga tagatggatt gcttgatatc cccaaccata aaacgattat ggccattaga
    30901 cagcagctct aataggcgct cctgcatgtg attgttatct tggtattcat caaccatgac
    30961 ctcatgataa tgaccttggt aagcttggcg aatatctgga gcctgttgta aaatctcaat
    31021 ggcaaaatga gctatatctg aaaattcaaa ggcattttct tgcatttttg cagccaaata
    31081 agcctctgaa aagctgatca caaaggcttg cagcacctcc aaaagtggta agctctcctg
    31141 ttgataagca aggatagtct ccaagtgcct aaatcttacc agctgctcct gtagcgattt
    31201 gaaaataggg tatttgtgac cggctacagt tatatcagct cctgaaggaa gtaaagctgt
    31261 tagctcctgt gctagctgac ctagtcgcgc tttaccgtaa aggctgtcaa aatgcaaagc
    31321 ccactcatat aagctgtcaa tcattttgag gtgcttagtg tatttggcag ttagcttgcc
    31381 agccttggtt gtttgagcgt aaccctccat gtctgtgagg tctcgcagct gatcagcagt
    31441 gtcctgcata caggctaaga gagcatctac agcttggtct ggaatatctg taaagctggt
    31501 ataggtctta gaccctcgta aaaagacctc tgccaaccaa ctgctaggat tggcagttga
    31561 ttgactgaag gcataaatgc tatcaacaat ctctctaaag gctgagctat ccttacgacg
    31621 tccagaaaaa ttctgcacca gctgtataaa ggctttattg tcagtctgcg acatatagtc
    31681 ttcaaaaacc tgacgaaaga cctcgcgctt taaaatgtcc tgctctgcct tatcctgtat
    31741 gatacgaaaa tgcggtgaaa tccctaaaac ataaccatgc tggtgaacca atttctgagc
    31801 aaaggcatcc atcgtaccaa tatcagcctg tgataaagcc tgcaattggt cattaaggta
    31861 ggccttgagc tgataatcct gagtctctgc tatagctgtg tgcagctttt tttcaattct
    31921 ctctattagc tcagtagctg cttttacggt aaaggtcgaa ataaataagc aatcaaccgg
    31981 aatacctctt agaatcttat ccaaaatgcg ctcaaccata acaaaggtct tacctgagcc
    32041 agcagatgct gatactaaga tattttgtcc actgctataa atagcctcaa tctgctgcgc
    32101 tgtccgcttg tgcgtcttat ctgataaggc ctcctcctgc tgcaaacgag caatagcctc
    32161 tggcgttaga aagccttcat caatcctcat gctttatctc ctcattcatt cgtgtcaaga
    32221 aagcctgtct cctttctttt gtcggtagga cgactaggcg tctcgcgtac cctagatcta
    32281 aatccgcctc aaagcgcgtg atggccttga gctggtcacc ctgaacagac ttgccgtctg
    32341 cggtataagg gtttattagg aaatgccctg ttttaatctg cttcaccgca gacaaatata
    32401 gctgctcatt ataagccagc agggtttcta gctcatcagt ctcataaagt gtgttgttaa
    32461 ggtgatagct gccattagcc agatattcct tggcttgggc taaaaaaatg cccttatagg
    32521 ttaactcctt gtaagccgca gctactagct gatcatcaag tgccttaaag tcagacagac
    32581 ttagccttgg ctcttgcatg tgcaggtaca tggcgccaaa caggccctgc cccttattct
    32641 ttagggcagc aagataggtc acaagctgag gactcaagcc attgtaaaag gcaacaatgt
    32701 caaataccct tgcactggat ttgtagtcca caatgcccag cctaccatca gctagctggt
    32761 caatacggtc aataacccct cgaataagca cttgctgacc cagcgctagc tcaaaggcct
    32821 cctcttgctt ggttatctgc aggccttgat taaggtctaa gacagaggct gttgagtaag
    32881 caatcccctt taggacctct aagctatatc gcccttcagc atcagcctga taaacctgct
    32941 gaaaagcgct ttgctgatta actgctgcaa tagctgcgcc tagcttttgg tcaaaggcag
    33001 cattagacct atccttggtt accaactcaa aaatacggtg caggtattga ccatgaatgc
    33061 gagcatctgg gtgaatagac tctggctctt gcagccctag gacatatttc aagaaatact
    33121 tgtattgatt gttataaaat acagtcaagg ccgatgaaga cagattcaag ggctgctgac
    33181 ttgaaaagcg ggtctcaata acctcaggtg ctactggctt agtagtcaaa tgatgctcaa
    33241 aagctggaag acttagctgc tcatcggcta gcctacgttt caaataacga agggcaaccg
    33301 tccaaaagtt tctgtcctca ctggtcatgt catctgcaat tccctgccga ttaatagcca
    33361 ccaagcgaga caagagagcc ttataattgc caatatctgc cgctgagtgt gacaaacggt
    33421 tctttccttt ttcaatgact ggaacaccaa gggcaattag ctccttcagg taaggagaga
    33481 catcatctga gctattcgtt aagcttgtag gcaggcttaa caccagctcc tgcgtcgctg
    33541 cattaaacag ggaaagtgct gtttggtgat ttttcttgat attttcaaag ctcggcacat
    33601 caaggcgctg gtaagaggca gtctgctcat tgatgcttgc cctttcctga tcagagatca
    33661 ggctggtgtt ttttgtctgc ttaggaaaat gggagcgact caggccaatc gcaaacacaa
    33721 agggcttgga atgcggctcc accagatcat aggatttgat agacacaaca tctaaggtcg
    33781 caggcactgt ccgataatgt gctgtctgca tgcccatctt gatcagagct agacagtctg
    33841 caagggtcat tttttcctga ccaaacacct gataaaaggt ctctaaaatg cctgtgaagg
    33901 ctttccaaac ctcctcgtcc ttttccctat cagtctccct tctactgcct gctagtgcct
    33961 caaaattatc agccagctga atggtcttaa aaaaggtcat tagcttatca agtagggaag
    34021 cccctagctg cttttgactc ttaaagagct gctggagagg agtcaccaca gcaagtcgca
    34081 gctgattcaa aagaggcaaa ggatactgac gtgaggaatt tagggtaaag ggtcttgaaa
    34141 atttggtgaa gccttgaata tcagcaaaga ccaagtattg ctcaagctga tccagctctc
    34201 cctcttgaaa gcgcccaaag agtcctgatt ttagtaagtt gacaatatcc tcacgtcgcc
    34261 aattgtatct gcggcctctt tctaaggatt cgacaaattg aaccaagggg tgagcagaca
    34321 tcggctcttg cttgccgata taataaggga tctcaaattt ctcaaaaata ggaccaattt
    34381 gcagctgata agacgccaca tcacctaaaa ggacaagcat atccttatag cgataaccct
    34441 gatagagctt ctcacgaata gcctttgcaa catgctcaag ctcctctttt tgattgagcg
    34501 cttgccagat cacaaccttg ctcttgtcct tggcactgag ctgccaatca agctttgaat
    34561 agtcatgatt ggcttcaaga agctgtgtta ggcgagaaaa tgacacatca aagacctttt
    34621 ctgacgttgt gtagatcggc ttggtttgaa attgctgtgc cagctgttgg ataaacgcaa
    34681 ggctcgcctc gtagagattt cccttggtaa aggctagtcg ataagccttt tgactgatat
    34741 aggctccaat aacgatttct tcacaggctt cgtttaagag cgctagcagc tgctcctcct
    34801 cagctgaaaa gcgggtaaag ccatcaatca ctaatacggt ctgccttagc tcgtcatcta
    34861 ggctcttgct tttgatagcc tcagcaagct gagccagcct acttgactgg tcgtaatctc
    34921 cttgtgcaat cagctgctca gccttggtca taatcgtgat caggtcctct tgcttttctg
    34981 gtctatcaag cgtcgttaag tcaaaggctg tcagattagc tgcttgcaat tccttatata
    35041 gctcaactaa ctgggcaata aaggcctgat ctgtccgtag ccggtgaaaa acctttagct
    35101 catcttcttg cagctgcatg agcacacgat aaaaaatcat ggctaagcca ttatcatcta
    35161 acgcttgtcg attagctgcc ttagctaagg taaaataacg cgccatctgc tcaaagcggg
    35221 tcaccgtaat agcaaaggaa ccctgctctg gcaataaggc taggacagaa cgttcctttt
    35281 caaaggatag agagttagga gcaatataaa agacacgata gcccttatca gcataagctc
    35341 ttgcctcttt gactaaaatc tctgtcatgg aatagctaat ctctgtgtat agtaatttca
    35401 taaaactcct tttatttgga cctgatacaa cgtctatgcc tccattataa caaatcagcc
    35461 ttgcttttcc cattgttaat gatctttcaa acgccacaag aagcgctcac agcatgaaaa
    35521 aagcctacca tttcacatct gctgctttgc gcaagaaatg ataaggcttt gtcttgtata
    35581 ggctcaaaaa acagactaag agctcctagt taagctgccc tgtgcttgtc tcttgtgatc
    35641 tgtccccagg cattcttttt acgctgataa ccaataaagc tgctcacctt gataagggtt
    35701 aataccgtat gaagaacaag gcattggtag atggcagcat agattaccca agccatatca
    35761 aaaagagtaa tgctactatt gttttgcaaa taaaccctat ttaaaaacga tgtcaacgca
    35821 ataagcacac aatagcaaat atagagcagc atcagtgaca caaaaaaggt tgtgtttaat
    35881 tgatggcata gcaaagacag cacaatgata ataacaccaa atgcctcaat aaaaggagat
    35941 aaaagctcaa acaaaagata cagcacatag gaaatgagta ccgtcgcttt aaaccgacag
    36001 cttacaaaaa actggagata ctttttcaag cattgataca gtcctaaaaa ccaacgacgc
    36061 ctttgccgac acaaatcctt caagcgactg ggcgcttggc tccagcaaat agcgtctgtt
    36121 tcatagccaa tacgataagg aatcttgttg ttatggcaga aaaaatgtaa tttcatcacc
    36181 agctccatat cttctcccag agtcccagtg tcataaccat caacagcaat cgcaagctct
    36241 tttttaaaca gtccaaacgc tcctgatatg attaaattcc cagcagcctg gtctaataaa
    36301 acacgagctc caaaaaaggc acaatcatac tcaattgcct gcgcacacga aataagctga
    36361 cgcggcaaat ggtagtctac gatcctccca gctgccaatg ctactccctg cgaaaccttg
    36421 accatgcccc caacagcaat gacagacgga tcctttgcag cagtctttgc aatacgctta
    36481 agcgaatcct cctgtagcat cgaatcagcg tccatgcaca ataaataatc gtattgagca
    36541 gcgttaatcc caagattgag gctatctcct ttgccgccat ttgccttttc aagcagggtc
    36601 agcttgatat gcttgagctg cttttggctt acagccttta gagggcgtgt tgggatccgc
    36661 tgattaatcg aacaagtcac cgcttctaaa tgaaactgct ccttcaagag cttggcggta
    36721 tgatctgttg acccatcatc aatgacaata atctcatagc agtcataatc aagcatcagc
    36781 aaggactcca ctgtttcgat aatggttagc tcttcattat aggccggaac caaaatagac
    36841 actggcggta aagaaacatc accaccaaca ggcgcttgct gtcgcctttc ataaaggtga
    36901 atagtcccaa caattaagga tagcagtaaa aagctcgcat aggcaatcaa aaacgctaaa
    36961 aaaagatatt gggagtattt caatactaaa aacagtagct gcactatcat tctcctttaa
    37021 catgcaatca cttgtgctta ccattcgcct tacaaaagcg tctcaaggtc tgcttcatca
    37081 aatacccgat attaaaggca aggatcgcta agcaaacgat tatataaaaa aacaacaggt
    37141 aataaatcat cttatcttct cctcttttcc tgccagacag cctgcacctg ctgataggag
    37201 gtctttaaaa cttctcttac ccttggacgc tcccagctca acagtggata ctctaccatt
    37261 gcaatgacct ttgattcctt tagcggtgca aaaccaatag ctattgcttc aatggctaat
    37321 tcctcaacac catagtgctc aaaataatca tcgtgtattt tgtttgaagc tggatcagaa
    37381 aaattgagca gctgccaggg aatcctaagc tcaatcagac gctcgccaaa agaaatatcg
    37441 gtctgcgaat caaaatgagc cgagcctcgt ttgccattgc cctgttttaa ttggccggta
    37501 gggtagcgct tcagtcctct ttttgcaatc ggaacctgat caatggctgc aaaaatacca
    37561 tcatttctca ccaccatatc aaccatagta aatcttggcg tatgcttgtt agggggaaag
    37621 acataaaagt cctttccatt aatctgccta aggtaattgg catcagtagc atggtagcgc
    37681 tcctgcacca agaggcgact gcctttgtgg tcatcaacaa caagggcaaa atcagcaaag
    37741 cgatcaaacc gagcgctaaa gccttcaata accctgctgc ctgttttggg cgtaatgtct
    37801 aagggaatga gccactgtct ttgtaagggc tgcttttttg tcgattcaat agcaatatag
    37861 aggtattttt cgtcctgatc aacgaggagc tgctgcccat ttttcttgta ggttagagct
    37921 ctagaccact catctgctgc cttttgccca tcaatagcat gcgtccttgg agcatgctca
    37981 aaggttaaga gaccataacc ttgagcctta gactgaacat caccccaaag aaagctttga
    38041 tgtttattgg ttgcaaagga ggtattccag ctcctagcag tccaatcgtc ctgccagcta
    38101 tggatcgttg caccacagca gccagacgca ataaaggctg tgtaatctgc catcaagcgc
    38161 tcgccttgat ccttttctgt caaagggctg gaagtcgata tcatttggtc cacacctctg
    38221 gctgtcgaat agccatagcc cgtcacaacc actgggacac gatgatagct cgtcagtagc
    38281 ttgacgtatc cctgatataa gggcatgcgc ttaatatccc caacaagcct atcagtaagc
    38341 cctagacggt caaatagcag ataatcccta taagccgagt gacaatccaa gagcttatag
    38401 gaagcaaaaa gaccggcctt aaccttagcg ctgggcttaa tattttcaat cgtcagttga
    38461 acatattttg ctgcctgaga ggcaaaggga tcctgataga caaagggatc tgattgaggc
    38521 gtatttgaaa agctcaccaa gtgctgccag ccatatttgc ggctctcgta tgacgtgatt
    38581 tcctccatga tttcagccag tatagcctca aaccgattgg cctgaggtgt cgttgcataa
    38641 taccttccct taaagcctac aggcttggcg tgattctgat gattggtata ggctatcgtc
    38701 ccactgtacc aatcatcacc aacaatatag ccgagtagcc atttactcat atcctgatca
    38761 taatgctgaa gccctaaatc cgaatgccag atccgttttc tcccatgaat cacatcaaca
    38821 ctagccctag cttcccttaa cagagtgcct aaataagcct tatctaaggc gctgatagaa
    38881 gaattgtcat gataagcatc tattctaaag ccctgtaata ggtacagagg atgacttgct
    38941 ctgtcattgt agcgtctcaa agcatggtaa aaagtgacgg gcataataac ccttaccctg
    39001 atcgtatttg cacccatagc tgctatttgc ttgaaccacc tatagtaggt tttctcatca
    39061 acgctaaggt ctcgtcgacg atagcctgct atggaactct ccacatcaac acccttgatg
    39121 agataaggag atcccttttg atcatatatg cgcttgtcct tggtgtaaaa gactgtccga
    39181 atagctgact ggttagagac cggcaggtac aagcgaccat caatatcaca acaataatag
    39241 ctcaagccaa tcacagacaa gagcaaacca acaaagatta aatatttctt catcactacc
    39301 tactccaata atgtattggt atttttagac ggtgcactgt actgatagag cgtctcaata
    39361 tgcttatcca gccatcgccc acgacgtcta ataaagtcct ttagttgctt aacagaggcc
    39421 tcatagctac tgtagttacg actggctggc acaaggtaat tagtggcatc gcttcttgat
    39481 ggcactgtaa acacatagcc ccacttatga taattgcgct gaatagccgg acctaaaaaa
    39541 gcaaccgtag catcaatata cttgatcaaa taatccgttg ataaaacatt ctgtcggagc
    39601 tgatgatacc ttgtgaccac cagcttaaca aagctaggat cctttagcag catgcaaaac
    39661 caaggagcat ctgatagggt aaagtccgcc tcatcataag gagcctcaat ctgattatca
    39721 aaggcgttgt taaaatccca gaccaccagc ttgagcttat cgcgcaaatc cttataaaga
    39781 taggttgaaa acttcccagc atcaatattt ctaaagaatt cattgataat aaaatagtct
    39841 gcaaaggact cttggtccag ataatcagtg tattgcttta aatcataaga atataggagc
    39901 ttttcgatat gactgatatc cttttcaata aactgctttt gcttaggcgt cagacggtgc
    39961 aggcttgggt atttaatgtc taaagaggac agacctgctt gattcgtata ggatacgtaa
    40021 tgatcaagag cctgcttagc cttgtgtctt ctatcccaaa caaggatata aggcgtttta
    40081 tcagattttc tatcactttt ttcgatgttt accctatgcc gcccctgctc aatactctcc
    40141 acagccaaat acagaccaca atactgatga tccaccacta actcgcaata cctgacgtta
    40201 ggtgcatagg tcatgatctc accggcaata ttgtagctaa gataatttcg gactagggtc
    40261 cgatctaaaa aaggaccatg cagcacccac tcagactcct tggacatgcc agccagcgag
    40321 actgcctttg gcttagctct tttattgata aaccttagct ttaaggattt cttgtcaaaa
    40381 tgacgtgacg aattgcccct ataagcaatc aatgctgtca aggacaagcg cggagactca
    40441 gacaggctgt gctctctatc tagctgatca cgaagcgaga ccgtcgtttt aatggttttt
    40501 tgccgctttg tctctccctc gtattccctt tgctctggaa tctgctgatg atgagtgtca
    40561 atgctaataa tcggcaaatg agagctaaac tccccagtgc ttctggagct ctttttgacc
    40621 gtctgcaaat ggtgatgaat acgctttgca gaggtcttag gaaaaccgat accacaaata
    40681 gcagctagca agagacacac cagcacaatc acataaatcg tcttttcttt catttacgtc
    40741 aaccagttat gtcatcgctt tgactaacaa tattaaaata atcaactcgc cccagctgat
    40801 aaacagcctc agttaacgga ttagcctgct gataggtgct gtcataatcc tttcttgaca
    40861 gctcaaagat catctcaata tcatcagacg tggtgttttt cacgctctgg atcgccttac
    40921 ccgaaaagta gttaaacact aaccgctcca gctcaatttc catttgctta tcacagcgaa
    40981 caatcaacaa cagtctattg tcatttctga cagctcccat aagcaacaaa agcataaaga
    41041 tcacgctgct accagttgca gcgacagtat aatcaccaac accacagcaa atcccaacca
    41101 caatcgtcca aaaaatatag actgtatctc tagagtcttt gattgctgtc cgaaaacgca
    41161 caaccgacag cgcaccgacc ataccaagag acaaagcaac attatttccg ataactgtca
    41221 tgacggttgc tgttaagacc gtcaaggtca tcaacgaaac attaaacttc ttgctatagg
    41281 cagtcccagt gtgggtatag gcatatgaca tataaatcac aatacttaac aaggctgcag
    41341 caacaatata cagcaaaaca tcttgaaagc tcaaggtccc acgctgttca aagacatgtc
    41401 ttaataattg tttcatctta atatctctcc taaaaacgat aatgcttgct gatagctctc
    41461 cccatgcaat acttgcttgc acttagctcg ctaccattaa cagactccaa aagctttttg
    41521 atataagaca acaaaaagcc attatacttg acctccaaga tgaccaaata gggatctagc
    41581 aggtaattct gaggcagatg atctgaaaaa atatcagcat tggtctcaga cccgataata
    41641 tgatgatcaa aggtaatgcg aatattgttt tcctttgcca caaatgcctt gcgctggtat
    41701 tcgatcactg tttttggctg atagagctgc attgacatgc gactatagca ttcagcagca
    41761 aagcgatcag gataagtcag caatatagac ttgtctccct taatcaacaa ttgagcgtct
    41821 gctctggtca acctcagaga tcgctttttt tgattgctcc cttgcttttg cttcatctcc
    41881 aacttagcaa atgagctctg actaccgtaa ttgcgcaggc gaatttttcg cctaagctca
    41941 ataccgtcct ctttttcctg ccagtcaacg tcctccaaag aatcaaaata caaggatcga
    42001 atcacatatc cctcactaga gctatgagca tctagacgca agagcttgga aaattcatgc
    42061 gataagcgat aataatcctc aatggtaatc aaatactttt tttcttgacg caatacctca
    42121 ttcacgccag tgtcctcctt tttcgtctgt aagcaatgcc ttaacaccaa gctgcctgta
    42181 acagcagcca acaaacctgt ctcataaata agtcagggca aataaggtga ttgttggctc
    42241 tacaagagtc aatcacctgc caaaatagta aatcctgcca tctgttgaaa taatataaac
    42301 cagctgatcg tcttgattgc aagacaggcg cttttgtgac tgatctagct gtctgctgct
    42361 aatatcagtt gcattagcct ccttgagcat ggcctgcttg agctgttgct ggatttttct
    42421 ggcttgcagc tcagaaatct caaagctgcc attaaccttt tgagccttgt gcttgtagac
    42481 cagtgccaca tggtctttag ctgttgtcct agcagtcgac aggagccctt ctttgttgag
    42541 ctgagtatgc tctcctacat caatggcaac atagtcatag ggtgcccgta tccggtgcgc
    42601 tgttagtatt gaggacaaaa tccctgtcac aaggcagatg cttatcgtag ccactatcat
    42661 ctgctgccgc tgcttacgaa tgaaccttga aaaagcacag acctccgcct gatattcctg
    42721 aagctcttct tcaaccttac tgtaatcctg tctaagatca gccaagtcag tctgacagtc
    42781 cttgcagctt gtcagatgag cctcaacaac cgctctacta taatcactca acgtatcatc
    42841 tacatataat ggcaacaaat cctggatcaa ctcacaatca tacttcatag ccatactcct
    42901 ctcgtaattg tcttttaata tgttttcttg ccctaaagac aagaaccttg gcagaggata
    42961 ctgtgatgcc aatatcctta gctatttttt cataggaatc tcccgaataa atcctcgcca
    43021 gaaagacagc ctgcattttc tctggaagat taaaaataat cgttagtgta atctctaaca
    43081 gctcccttct tgctatctta tcaagtggtt catcatgccc tttagcatca acgatttcta
    43141 agctttccat cgacatattc tcatattttt tctttttaat ttctgtaaag aaggtgttct
    43201 ttgcaatggt aaataaccat gttttgattg aactatcccc actaaattta gcaatattac
    43261 gataagcctt tagaaaagtc tcttgagtaa tatcatctga taaactattt tgataacagc
    43321 acagcttatt tacaaaccta taaacatcat ctttatattc taaatatatg tcctcaaatt
    43381 ccaacagctt gtctcctctc aatacaccct taaccattag accgtccaat ctgccaaaag
    43441 ttacagatta atttaatttt tagtataagc tgtcatcaag tcagataaat agtaatgatc
    43501 tatcatctta ttattgactc aaacgacaaa ttatattgca ttttagtata agctgtcatc
    43561 aagtcaggta aataacaagg acatatcatc taacatttga tccagacaaa aaagacctga
    43621 ttctgtaata tacagaacca agtctttctc aatagacatt gactagatga ttgatttata
    43681 gcgacatagc tagataggct atgacttacc gtcttttgga tttggagaca agcccgccaa
    43741 gacctgccaa gataccactg ccagcaagag ccaataaagc atctagctga ctagtgcctg
    43801 ttttagggag agtcttagct gagaactgag aaacctctcc agcagtctga gcagcaacta
    43861 atttctcctg atgatgggct gcttgatcag tcattgcacc taaagtcccc ttatcagact
    43921 gggacgccct aagacggata atggtagctg ttaagcctga tagcttgacc ccgtccttgg
    43981 ttagcacaac cccctcagga cttgccagcg cctcggtgcc tgcttgcttg gcatcgacga
    44041 taacctcacc agcaagaaga gcctgaaact caccagttag cctaatggta cggtcattgc
    44101 tatcagcatt gacaaagaca gcataaacat caccattgct tgctgttgtc tgataagcaa
    44161 tcaccaaatc ctgtgccttg atcccatgct catttggaac agtgatcagc ttgaccttct
    44221 ggtctatctc agccttactt gccaagcgaa aggcatctgt cgaacggcgc agcgcaatca
    44281 atcccttagt aaaggcctga cttgtcgtgc tttcagggta gcgctctgta tccgttgcct
    44341 ttgcccagtc aaaatgatta atggcatctg tcgaatcata ggaatcatga ataaagtatg
    44401 ggtattcaaa tggtgttccg tcctcattga ccaagaggtg tgatttattt ggcaccttgt
    44461 catcagcgac cttgccctta taggcttcgt ccttaaattg ctttgtacga ccatattcct
    44521 gaccagcatg taggaaaggg gtgccttgag aggttagcac caagaggttc cctaggcgca
    44581 agcgacgatg aatctctgcc gcatttgctg caacagacgg atccttttta atagactggg
    44641 cgataatatc aaacaaggtc aggttatcat gtgcagcgat atactgaatc acatcacccg
    44701 gatcatcagc caaaaagtta gtcggctgag ccttgatatt atgaaaaatg gtcatgatat
    44761 ccctagcacc gcccgtaata aaggctggag agccttcatt tggaaagcct gatttgagct
    44821 gattgcgaaa atcatctgag aaggaggcaa cggtatctgt ctgtgacatc cagctttggt
    44881 ccgcaggctg ctcaggcatg tgctcatcac cctgataggt gacccagccc tcaccaagca
    44941 tgatgatatt cggattaagt gccttagctg ctaaaaaggc tttttcaata gctgctgcat
    45001 catggtcccc catcatgtca aaacgaaaac catcaacctt atactcatcc accagataag
    45061 taatcgaatc caccaaaaca cgacgactca tgtaatgcgt tgtcccaagt cgtccaccac
    45121 caaatgaggt cctagcagtg ccatcagcat tcataaagtg ataataattc ggctccaggt
    45181 cctcaaaaat atcaacatta gctgtatgat tgtagaccac atcaaggata acccccatac
    45241 cacgcttatg gatttcatta acaagctgct taaattcctc aatgcgctta gctgggtcgg
    45301 ttggatcagt cgaatacata ccagtcaagg caaaatagct ttgtggatca tagccccagt
    45361 tgtaattatt atcacttgag ctgtaggtca gcatacgctc cttgttggcc aattcgttga
    45421 caaaataata gctcatcaca ggcagcagtt gaacatgcgt aataccaagc tccttgagat
    45481 aatccaactt ttcaacaaag gcagcaaaag tcccaaattg agcctttaga tcattagcaa
    45541 tcgcctgatc tgaggtaaaa tcacgaacat gtgcctcata gataatggcg tcctcacgct
    45601 tatgaaagcc cttaatatca gcaaaggcca gctccttatc cccaatagca gcaggatcaa
    45661 caatggccgc cttagccacc ttataggacg ggtctgtctt agcaagctcg ctgttccatg
    45721 ccgctaacga tttggcataa gggtccagca caaggacaga cttgccattt ctagtaatct
    45781 cataatgata gaaatagcct ctataatctg aaatcccaag tccgctatct gctgatagag
    45841 tgattgacca ctctccctta tcaccctttg ctagagcgag attaccaatc accttggtct
    45901 gatcagcctt atcatacaaa acaagtgaca ccttatcagc acttggtgac caaatcgtca
    45961 gatcaacctt agcacctgct tctctcacac gcgctcctag ctcaccgtca taagcataca
    46021 ggctatcctt gtattgccaa tttggcctag cctggaagct ctcatgatga aaggtcaccg
    46081 tataagtggc cactgcttga ctaaaatcac ctgtgatgac agccttatga gtcttttcat
    46141 ctaaggtgat atcagtaata gcaactgctt ccttactgtc agtgctgatt tttaattctt
    46201 ttaaaaggct ttccttatcc acatctgcta gagtcgtaaa gctcgcctca atactgcttg
    46261 ggctgacctg ctgagcaccg attaatctaa ctgtattaac aaaataaggg ttcgtataaa
    46321 tggttggatc ctcgtctttc aagaaaattt gggtgtgatt ctttaaatct ttaaaaatat
    46381 aatcattggg ctgaatttta acagcgtcac ctgtctgacg ctcatctagc aagagaaagc
    46441 ctagctcatt ggtatcagct agcttgacat ctatataagc accatatcga ccgacctgct
    46501 taaaatcaat accatctggc caagcgccct gctgactagt cattgacgca tcagcacttc
    46561 cccaaagcca gagcgatttg ttgtcataat ggccatcact gcgataataa ttgatacgga
    46621 tatagccctg agccagcggc cgatagtaag acagctcctg gccatcaatc cagacctcat
    46681 tcatcttagg gctgagaagg tctatggttc gatcgcccgt cagattgtct cccttagtgt
    46741 tattgatcaa aaagctaacc ttattggctt gattggctga aagcttaacg tccatgtaat
    46801 agccatagtc atctgtcttc gctagactaa aattggtagc cccagtcggc cagcctccca
    46861 gctgatcaga tggtgtctca acatcgtccc acacccaaag accaagcgag gataggtctt
    46921 gagctggcag ggtcttgaaa tgcagccgca aggtctgctc cgctatcggc tcctctgagc
    46981 ttgtagcttc tggtgtctct agagagctgt ctgtcgtaac agacactatc gatgatgaag
    47041 gctgagactg gtctgtagtt tcctcatgcg cctgatcctc tacaagaggt acagctactg
    47101 gctgaacttc cttgacagta tcagcattga cagcagctga caccttagtc acatcagaaa
    47161 taccagcaat atcactaatg tcagtagctt ctggtagctc atttgagcct tggtcagcag
    47221 cctctgactt gaccatgacc gcaccatcag caggctcaac actcgtcaga ctctcagctg
    47281 ctgctgtgat ctgcccacta gctgtcccca aagaaaaagc ggttgcaata gctaccgaag
    47341 ccactccaag cttaagctta cgaatgccaa ataattgacg ctcttcaaac agcgcttgat
    47401 tttcccctaa ccttttcatc attcctccgt ccttatcctg atagttatta acaccttaag
    47461 tatacaaaag aaatcacaat agtgcaatcg ttttctttat tgaaaacaat gatatttatg
    47521 aacaaattag acaagaatca acgcaagcga tttccttact gataaatacc tgctcccctc
    47581 actaagacca gcccactgca aagcagaaaa gtagcctaaa gagccttagt aacagataaa
    47641 tgagcttaat gttgcttcat caactagctg gctgcaaccg ttttgctctg atgtggtaac
    47701 gtcttgtcat catgactaag cttgacaaaa aacgctgtta gttacataat caacggtgct
    47761 tggtagcctt ccattactcc tttgattgtt ataccctaat gatacacaaa acctcagttt
    47821 ttatagtaga atattacact ttgttttgac aaagatgttt aatcttgcta aaataaactt
    47881 atcaatgagg gagtaccaat gatgacattc gaattcacat cgttattcga tttacaaact
    47941 gcttttccaa cagagcaggc ttgcataaat catttagaaa atatcacttg gggtgacgtg
    48001 gtgatcagcc cttttgacgc tacctcaaag gtctataaat gcaagggaaa taaataccgt
    48061 tgcaagaata cagggaagta tttcactgtc aaaacaggta ctctttttga taatactaag
    48121 attaagctac aaaaatggtt tatggcaatc tggcttgtga cttctcacaa gagaggaatc
    48181 tcctcagtgc aattatcaaa agagattgca gtgacacaaa aaacagcatg gttcatgtta
    48241 cagcgtattc gtaaatgctt tggctctgaa aactgagatc cacttggtga cgtcgttgaa
    48301 gtagataaaa ctgatattga tggtaaaaat aagaaccacc atgatcctaa gaaggcaaaa
    48361 acgttcaaga accatccttc tctgaaagat aagtcggcag ttattggaat ggtgcaacaa
    48421 aaaagtaagg ccaacgctca tacaatactc gtgattactc tgatagtcgg cgttttatct
    48481 tttatcagct aatgctgata tgcgaacaac ttataaggag ctgatcaatg gttaaacatg
    48541 caaaaactaa cctacacttt gaattagaaa gatctatctc tcgcaaagtt gatagtaaat
    48601 tgatagccta tcaagtcagt ctttcagatg gcttttatga caaatacacc aaattatggg
    48661 ataaaaccta ttcatttgat tttgtcatca accatcgtgc gttttatgct cagttgacca
    48721 aaagatgtgt ttacgatgtc cttttgcaaa ctttggaaaa aatcagtaga aaagccattg
    48781 caaagcaact agcagagctt gaagccttgg ttgatgtttc ggaaagtaag gaagactttc
    48841 agatattttt cgagaaaaaa tacaaactat catttcctga tttgaagaat tgtgtttatc
    48901 caaagaaaaa ggaactttcc gattttgatc aaaacctctg gatagctcta cattataacc
    48961 ctagaaagga gagggataca taatgacaac atggtatgat tacatggtaa gagccagcga
    49021 acactctgga agtgatggag acctctggtt tcgttacctt tacaaggtta tcaaagacaa
    49081 agaaaccaaa ctaactactg atgatgtgga gcagttatta aaaaatccga atctaactcc
    49141 ttttcagaag gtaactctgc aagatgcttt aacagaaggt acgcatacaa gagagcatgt
    49201 tttacaggca aaccgtaaaa gtcagccaaa ggatattttg aaactcttta gagagggaaa
    49261 ctatggataa aaaaatctta ttcaaagctc tgaatacaga actagctaaa gaaaatatta
    49321 gccttgacat tatctgtgtc ggtggttttg tccttgaata ttacaatctg cgaggaacac
    49381 aagatatcga tgccttttat caagaaggtg ttaacatcag gcagatgatc aaaaaggtgg
    49441 gagatgagtt tggcgttaat gaacctgatg agctttggct taataattca gttgccaatc
    49501 ttaatagaat accacctaaa acgatttgtg agacagtatt tcactattct aacctaattg
    49561 tccttgtccc acccttgtct tatattcttg gaatgaagct agaaagcgga cgagataggg
    49621 atagacaaga tgccggagac attattaagc tagctaatat ccgttcccct aaaaaactta
    49681 tcaatacact tgaagagtat gattttcaac ctgatatttc aatgatttta gaagtctttg
    49741 aaatagctta tggcatggaa tggttagcaa actatatgac cgaacaccca gaagaattta
    49801 ggcattatta aaagacgatt tctgtttgga agtcgccttt tttgatgttt ttgaaaacac
    49861 cttgagatta gtctaaacta atctccataa gcaaaaaaca gcttagcccc gtctgggagt
    49921 aagctgtttt tgctgtaatg tatgagataa ttaggctaac atcaatcatt acataaaggg
    49981 aataaagggt taatgtttct tgcgtttgcg tgatactaca gctacgccta gacttgccaa
    50041 tacggcaagg gctgctgctg taaagaatgg agctgttgct tctcctgttg acggaagctt
    50101 gtgttccatt gctttaggta ccgctggttt atctcctttc tgtgcttctg gtttaggcat
    50161 tggtttagcc tctggcttaa cttccggttt agtttctggc ttaggcattg gttttggttt
    50221 agcctctggc tctggcttag gttccggttt aggcattggt ttagcctctg gcttaacttc
    50281 cggtttagtt tctggcttag gcattggttt tggtttagcc tctggctctg gcttaggttc
    50341 cggtttaggc attgg
//
LOCUS       DARYUW010000008        47156 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYUW010000008 DARYUW010000000
VERSION     DARYUW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47156
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            627..2459
                     /gene="lepA"
                     /locus_tag="TVW11_000400"
     CDS             627..2459
                     /gene="lepA"
                     /locus_tag="TVW11_000400"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1364537.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            3001..3438
                     /gene="msrB"
                     /locus_tag="TVW11_000401"
     CDS             3001..3438
                     /gene="msrB"
                     /locus_tag="TVW11_000401"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1364538.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            3726..4745
                     /locus_tag="TVW11_000402"
     CDS             3726..4745
                     /locus_tag="TVW11_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1364539.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            5089..5514
                     /locus_tag="TVW11_000403"
     CDS             5089..5514
                     /locus_tag="TVW11_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1364540.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            5529..6020
                     /locus_tag="TVW11_000404"
     CDS             5529..6020
                     /locus_tag="TVW11_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1364541.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            6038..6847
                     /locus_tag="TVW11_000405"
     CDS             6038..6847
                     /locus_tag="TVW11_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1364542.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            6844..7671
                     /locus_tag="TVW11_000406"
     CDS             6844..7671
                     /locus_tag="TVW11_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1364543.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGVVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            7861..9495
                     /locus_tag="TVW11_000407"
     CDS             7861..9495
                     /locus_tag="TVW11_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1364544.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            9499..10284
                     /locus_tag="TVW11_000408"
     CDS             9499..10284
                     /locus_tag="TVW11_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1364545.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            10308..11318
                     /locus_tag="TVW11_000409"
     CDS             10308..11318
                     /locus_tag="TVW11_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1364546.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRVFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            11571..13355
                     /gene="uvrC"
                     /locus_tag="TVW11_000410"
     CDS             11571..13355
                     /gene="uvrC"
                     /locus_tag="TVW11_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1364547.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            13483..14085
                     /locus_tag="TVW11_000411"
     CDS             13483..14085
                     /locus_tag="TVW11_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1364548.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            14166..15575
                     /gene="pepV"
                     /locus_tag="TVW11_000412"
     CDS             14166..15575
                     /gene="pepV"
                     /locus_tag="TVW11_000412"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1364549.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(15842..17218)
                     /gene="mnmE"
                     /locus_tag="TVW11_000413"
     CDS             complement(15842..17218)
                     /gene="mnmE"
                     /locus_tag="TVW11_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1364550.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            17490..17711
                     /locus_tag="TVW11_000414"
                     /pseudo
     CDS             17490..17711
                     /locus_tag="TVW11_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            17834..18148
                     /locus_tag="TVW11_000415"
     CDS             17834..18148
                     /locus_tag="TVW11_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1364551.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            18153..18485
                     /locus_tag="TVW11_000416"
     CDS             18153..18485
                     /locus_tag="TVW11_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1364552.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            18487..20085
                     /locus_tag="TVW11_000417"
     CDS             18487..20085
                     /locus_tag="TVW11_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364553.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            20079..20765
                     /locus_tag="TVW11_000418"
     CDS             20079..20765
                     /locus_tag="TVW11_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364554.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            20787..21473
                     /locus_tag="TVW11_000419"
     CDS             20787..21473
                     /locus_tag="TVW11_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364555.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            21495..22172
                     /locus_tag="TVW11_000420"
     CDS             21495..22172
                     /locus_tag="TVW11_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364556.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            22179..22493
                     /locus_tag="TVW11_000421"
     CDS             22179..22493
                     /locus_tag="TVW11_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1364557.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            22941..23624
                     /gene="rpiA"
                     /locus_tag="TVW11_000422"
     CDS             22941..23624
                     /gene="rpiA"
                     /locus_tag="TVW11_000422"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1364558.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            23702..24913
                     /locus_tag="TVW11_000423"
     CDS             23702..24913
                     /locus_tag="TVW11_000423"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1364559.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            25126..25935
                     /locus_tag="TVW11_000424"
     CDS             25126..25935
                     /locus_tag="TVW11_000424"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1364560.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            26026..26811
                     /locus_tag="TVW11_000425"
     CDS             26026..26811
                     /locus_tag="TVW11_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1364561.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(26944..27852)
                     /locus_tag="TVW11_000426"
     CDS             complement(26944..27852)
                     /locus_tag="TVW11_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1364562.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            28192..28641
                     /locus_tag="TVW11_000427"
     CDS             28192..28641
                     /locus_tag="TVW11_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364563.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            29262..29954
                     /gene="pyrF"
                     /locus_tag="TVW11_000428"
     CDS             29262..29954
                     /gene="pyrF"
                     /locus_tag="TVW11_000428"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1364564.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            30014..30649
                     /locus_tag="TVW11_000429"
     CDS             30014..30649
                     /locus_tag="TVW11_000429"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1364565.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            30701..31444
                     /locus_tag="TVW11_000430"
     CDS             30701..31444
                     /locus_tag="TVW11_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364566.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            31679..33133
                     /locus_tag="TVW11_000431"
     CDS             31679..33133
                     /locus_tag="TVW11_000431"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1364567.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            33253..34119
                     /locus_tag="TVW11_000432"
     CDS             33253..34119
                     /locus_tag="TVW11_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1364568.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            34147..34800
                     /locus_tag="TVW11_000433"
     CDS             34147..34800
                     /locus_tag="TVW11_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1364569.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            34931..35338
                     /locus_tag="TVW11_000434"
     CDS             34931..35338
                     /locus_tag="TVW11_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364570.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            35350..36003
                     /locus_tag="TVW11_000435"
     CDS             35350..36003
                     /locus_tag="TVW11_000435"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1364571.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            36235..37509
                     /locus_tag="TVW11_000436"
     CDS             36235..37509
                     /locus_tag="TVW11_000436"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1364572.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(37563..38210)
                     /gene="plsY"
                     /locus_tag="TVW11_000437"
     CDS             complement(37563..38210)
                     /gene="plsY"
                     /locus_tag="TVW11_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1364573.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            38343..40292
                     /gene="parE"
                     /locus_tag="TVW11_000438"
     CDS             38343..40292
                     /gene="parE"
                     /locus_tag="TVW11_000438"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1364574.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            40394..41209
                     /locus_tag="TVW11_000439"
     CDS             40394..41209
                     /locus_tag="TVW11_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1364575.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            41684..44143
                     /gene="parC"
                     /locus_tag="TVW11_000440"
     CDS             41684..44143
                     /gene="parC"
                     /locus_tag="TVW11_000440"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1364576.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            44241..45266
                     /locus_tag="TVW11_000441"
     CDS             44241..45266
                     /locus_tag="TVW11_000441"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1364577.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            45334..45564
                     /locus_tag="TVW11_000442"
     CDS             45334..45564
                     /locus_tag="TVW11_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1364578.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            45625..45705
                     /locus_tag="TVW11_000443"
     tRNA            45625..45705
                     /locus_tag="TVW11_000443"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45659..45661,aa:Tyr,seq:gta)
     gene            45744..45815
                     /locus_tag="TVW11_000444"
     tRNA            45744..45815
                     /locus_tag="TVW11_000444"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45776..45778,aa:Gln,seq:ttg)
     gene            45943..47145
                     /gene="rpsA"
                     /locus_tag="TVW11_000445"
     CDS             45943..47145
                     /gene="rpsA"
                     /locus_tag="TVW11_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1364579.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        13474 a         8792 c        11111 g        13779 t
ORIGIN      
        1 ctaagagata tttaggagtg gctttgtcat ttaatgcaga ttatgatata gcaggagaca
       61 tattgttgaa gctgtctatg tcacttttgg tggcaggtag gtcttattgg aattggtgac
      121 ttatgacatt tatcggtggc tgtaagcgtt tgactttttc acgtttcata gtggtccgct
      181 ctggaatgag tgggtatttt ttcagaatat gatcaaagat agatgacatg ttttacagca
      241 ggctatagct ggtatgattt gtttaaaaaa tcaaggccaa tgataagtgc tgggtgacat
      301 aagtcttatg gctttacttc ttgttagctt gtgtcagcag gtgctgagtc aatcgttgta
      361 ggaattatcg taaacctaac agtagctgct gttctatttg tttattttct ggtttctatt
      421 caaatttcta aaatgctagg gtaacaaata tgaaacaagc aagtggcgta ctgcgaacag
      481 cttgataact tattgcctgc ttaaagaggg tgctgttatg cttggtttta ttaggcttat
      541 ggcatgggat taaaaggttg ctgtagcgcc attgtcatta ttttggtaca ataataggta
      601 aaagactaaa tgtataggaa aatagaatga acagtcaaga attaaaaaaa cgtcaggaga
      661 acattcgtaa tttctctatt attgcccaca ttgatcatgg taagtcgact cttgctgacc
      721 ggattttgga aaagacagaa acggtttcaa gtcgtgaaat gcaggcacag ctccttgatt
      781 caatggactt ggagcgggag cgtgggatta ccatcaagct aaatgcgatt gagctgaatt
      841 ataaggctaa gaatggtcaa gattatattt ttcacttgat tgatacacca gggcatgtgg
      901 actttaccta tgaggtgtcc cggtcactag ctgcctgtga gggtgctgtt ttagtggtgg
      961 atgctgctca ggggattgag gcacagaccc tagcaaatgt ctatctggcg cttgataatg
     1021 atttggaaat tcttccagtg atcaacaaga tcgatttgcc agcagctgat cctgagcggg
     1081 ttcgtcagga aattgaggac gtgattggtc tagatgcttc ggaggctgta cttgcctctg
     1141 caaagtctgg gattggtatt gaagatattt tagagcaaat tgttgaaaag gttcccgcac
     1201 cgtctggtga tgttgatcaa ccgctgcagg ccttgatttt tgattcggtt tatgatgctt
     1261 atcgtggggt tatcctgcag gtgcgtgttg tcaatggtat ggtcaagcca ggtgatacga
     1321 tccaaatgat gtcaaatgga aaaacctttg atgtgactga ggtggggatt tttaccccta
     1381 aggctattgg tagggatttt cttgctactg gtgatgttgg ctatattgcg gcctcaatca
     1441 agacagttgc tgatacgcgt gtcggtgata cggtcactct ggctacaaat cctgcagcag
     1501 agcccttgca tggctacaag cagatgaatc caatggtgtt tgcagggatt tacccgattg
     1561 agtctaacaa atacaatgat cttcgtgagg ccttagaaaa gcttcagctt aatgacgcta
     1621 gcttacagtt tgagcctgaa acctcgcaag cattgggctt tggttttcgt tgtggctttc
     1681 ttgggctgtt gcacatggat gtcattcaag agcgtttgga gcgtgaattc aacattgatt
     1741 tgatcatgac agctccgtct gttgtctatc atgttaatat aactgatggt gacatgcttg
     1801 aggtctctaa cccgtcagaa tttcctgatc caactaaggt agatagtatt gaggagcctt
     1861 atgtcaaagc ccagatcatg gtgccgcagg agtttgttgg tgctgttatg gagttggccc
     1921 agcgtaagcg tggagatttt gtgacgatgg attatattga tgacaatcgt gtcaatgtga
     1981 tttaccatat tcccttagct gaaattgtgt ttgacttctt tgataagctg aaatcatcaa
     2041 cgcgaggcta tgctagcttt gactatgaaa ttgctgaata ccgtcgctcg cagctggtga
     2101 aaatggatat tttgttgaat ggtgataagg ttgacgctct tagctttatt gttcatagag
     2161 catttgccta tgagcgcggt aagctgattg ttgagaaatt aaagaaaatt attcctcgtc
     2221 agcaatttga ggtgccgatt caagcggcta ttggtcaaaa gattgtggct cgctctgata
     2281 tcaaggcctt acgcaaaaac gttcttgcta aatgctatgg tggcgatgtt tcccgtaagc
     2341 gtaagttgct tgaaaagcaa aaggctggta agaagcgtat gaaggctatt ggctctgttg
     2401 aggtgccgca ggaggccttc ttgagcgtcc tatcaatgga cgatgagagt aagaaatagt
     2461 gacatgttaa gtaaggagct ggatcatgcg atctggctct tatgcttgat gtctcgatag
     2521 gctagaaaat agggcttgtg tcatgatagg cttgtatgtt tgagatggtt tggaacataa
     2581 tgactctatc atatctgtag tggattgaca aagagccgta aaccattgat atttggatag
     2641 ttaatttcga gttattctgt agtactctct taaggtcttt catatgagct tttctaatgt
     2701 tggtttggtt gcttttcatg ataagtcata tgggattttt ttggtatact gaaaaaagcc
     2761 tatagcctct acagtggcgt ctccctctac agagatgata gagccagagt gattgttacg
     2821 atctggagat gtggcgctag gcattaatgc aggaggactt aaccagattg ctgttaggct
     2881 tgaaatctta agctatattg attgtcagct tgatttagag aagtctaagt ttatggctca
     2941 caaatgctcg gtctttttgt tacaatagag ttaatcagtt atttttataa ggagacagct
     3001 atggaatcta aggaagagct tcgccagcgt attggagatt tggcttttga ggtgactcag
     3061 catgcagcga ccgaaagagc ctttacaggt cagtatgatg atttttttga gaaggggatt
     3121 tatgttgatg tggtgagcgg agaggtgctc ttttcctctt tggataaatt caattctggc
     3181 tgcggctggc ctgcattttc taagccgatt cagcatcgta tggtaaccaa tcaccatgat
     3241 tcatcacatg gcatgcggcg tgttgaggtt aaaagccgcg aggctggctc ccatttgggg
     3301 catgttttta atgatggccc taaggaggca ggaggcttac gctattgcat taactccgcc
     3361 gcgctgaaat ttatccccta tgatcaaatg gagcaagagg gctacgccga atggttaggg
     3421 atttttgata agagctagga attgctagcg gccaatgaaa aggtagagct cttagccaat
     3481 gctagtggct aaatcaaaga aataaaaagg tggctaaagt acatagaaaa aagaggtaag
     3541 cagattggca ggtggtcaat ctgctttttg tgaggagact ttcagcctgc tttgcgctaa
     3601 aaagtatgaa accaataaac cacctactat gcgggtgtgt gtcggtggtt agcttaagtt
     3661 ttttcagttc ggttttacaa gcttctctaa aaggactata atagctaatg gaaaaggaga
     3721 ttcatatgct aacatcttta gaaaaattac cgggcgtttt actgtgcttg ctgttagcac
     3781 tgcctgcctg gtatttggga agcttatttc ctattattgg agcgccagtt tttgctattt
     3841 tattgggaat gctattggcg cttgtctatc agaagcgtga ctacactaaa tctggaatcg
     3901 cattgacgtc caaatatatt ttgcagctgg ctgtggtttt cttgggcttt ggcttaaacg
     3961 tgacacaggt tttagtggtt ggcttgcaat ccctgccgat tattgtagta acgattgtga
     4021 ctgccttggg cataagctat ttgttcaaaa gatggttaag gctaccagcc aagacagcta
     4081 tcttagttgg tgtgggctcg tctatttgtg gtggctctgc tattgcagcc acagctcctg
     4141 tcattgatgc gcaggacgat gacattgcca aggccatttc ggttattttt ttgtttaata
     4201 tcttggcggc cttgctattt ccagctttgg gtcagatgct tggcttatca aatcatggct
     4261 ttgctatttt tgctggaaca gcagtcaatg atacctcatc tgtaacagct acagcgacag
     4321 cctgggacgc tattcaccag tctaatacgc tagatggggc aaccattgtc aaattaacca
     4381 gaacgctggc tattattccc ataacacttg gcttatctat ttaccaaacc aagagcaggc
     4441 aggcacatac gacagagggt tcctttagcc tcagaaaggc ttttccgacc tttattgtct
     4501 ttttcttgct agcttccttg ataaccacct ttgctgctag cttaggtctg ccaatggcaa
     4561 tctttcatca gcttaagcta ctctcaaaat tctttatcgt tatggccatg gcagcgatcg
     4621 gacttaatac caatctagtg accttagtca aaactggtgg taaggccatt ttgctgggtg
     4681 ggatttgctg gctagcgatc acatcagtta gcttagcaat gcaggcagct ttggggagct
     4741 ggtaactgat gagaatagct ggtgatacgc tgctttatag gaaaagcaaa gcccttgctg
     4801 ctcctaaaaa agcttgttag agcagctcac ttagctgtta agtgtggctt ggtggggtgt
     4861 aagtaggctc tatcagttag aaaagccatc agaacaaacg ctatcattaa gctgaagccg
     4921 gggaaactcg gcttttacgt tatgcagaat tgtctacata ttgaatagga ttatccattt
     4981 taaaaacgtt ttcatttgat agaatacaat tatagcttgg ttattagggt aaacgagatt
     5041 gaacttctta tctggtttag cttaagtaaa aaagcagttg gaggaagcat gaaacgtaaa
     5101 tttttaattg gtagtcatgg gagaatggcc agtggattga aaagctctat tgacattttg
     5161 gctggtagag gtcaggaatt acaagtcatt gacgcttata ttgatgatag tgattatact
     5221 gagcaggtat tgacctttat cgaagatgta gcagctgacg agcaggcact gatttttaca
     5281 gatttattag gtggcagtgt taatcaaaaa atagtaactg ccctaatgga cagtggcaag
     5341 gaaaatatct ttttgatttc aaatagtaat cttgcagcct tgctatcgtt gatgttttta
     5401 aagccagaag aagagctgac aaaagacgag attgtagcaa cgattaacga ttctcaggtg
     5461 cagctggtgg atctagctcc agcgacagcc gcagaagatg acttttttaa ttgaggagga
     5521 aaaatgaaat gattacacaa attcgtgttg acgacagatt gattcatgga caggttgctg
     5581 ttgtttggac caaggagctt aatgcccctt tgcttgtggt ggctaacgat gaggctgcta
     5641 aaaatgagat tacacaaatg actctaaaaa tggcagttcc taatggcatg aaattattga
     5701 ttcgctctgt tgaggactct atcaaggttt tcaatgatcc acgcgcagtg gataagcgta
     5761 tttttgtcat tgtcagctcg attaaggatg cttgccagat tgcaaagcag gtgaaggact
     5821 tagaggctgt taacgttgca aatgtagggc gctttgacaa gtcagaccca gcaactaagg
     5881 tcaaattggc ttcaagccta ttgttaaatc cggctgaatt agaagcagca aaagagctgg
     5941 ttagcctgcc taacctagat gttttcaatc aggtactgcc atctaatagc aaggttagcc
     6001 tgagccagct catcaaataa agaaaggtgt aatgactatg ttagtaccag caacaatggc
     6061 agccttagct gtattgattt gtttcggggg aaattattta actggccaaa gcatgatgga
     6121 aagaccgctt gtggttggtt tggtgacagg attgctctta ggagatatga aggtcggtat
     6181 cttgatggga gcgtcactag aggcactttt cctaggaaat gttaacattg gtggtgtcat
     6241 tgcagcagag cctgtaacag caacagctat ggcaacgacc tttaccatca tttcacatat
     6301 tgatcaaaaa gcagctatga cgctagctgt tccgattggc atgctagcag cctttgtggt
     6361 catgtttttg aaaaatgttt ttatgaatat ctttgcgcca atggttgata aggcagcagc
     6421 ggcaaaccat cagggcaagc ttgtcatgct gcactatggc acatggattg tctattattt
     6481 gattattgcc tctatttcct ttatcggtat cctagttgga agcggacctg ttaacgcctt
     6541 tgttgagcat attccacaaa atctgatgaa tgggctaagt gcagctggtg gtcttcttcc
     6601 agcagtcgga tttgccatgc tgatgaagct cttatggaca aataagctag cagttttctt
     6661 cctattaggc tttgtgttga cagcttattt gaagctacca gcagtagctg tggctgcact
     6721 tggtgcagtt atctgtgtga tcagctcgca gcgtgattta gagttagatg ctattactaa
     6781 gggagctatc agtaaccaaa gcagctttga ctctaaagaa tcagaagagg aggacttctt
     6841 tgcatgagat ctcaagacaa tttaactaaa gaagaaagaa aaatgctacg ctctgttttc
     6901 tggcgttcat ggaccatgaa tgctagtcgt acaggagcta cgcaatacca cgctgttggg
     6961 gttatctata ccttgttgcc tgttatcaat ctcttttata agacagataa ggataaggca
     7021 gacgctcttg ttcgtcacac cacttggttt aatgcgacca tgcatattaa taactttatc
     7081 atgggcttgg ttgcctcaat ggaaaagaaa aacagtgagg atccaacctt tgacgctagt
     7141 gctattacag cggtcaaggc ttccttgatg ggacctattt ctggtgttgg agattccttt
     7201 ttctggggta ttttgagggt cattgcagct ggtattggga tttcacttgc tagcacaggc
     7261 tcagcgatgg gagcagtagt ctttttactt ctctataata ttcctgcttt tatcattcat
     7321 tattatagcc tttatggtgg ctattctgtt ggtgctggct ttattaaaaa gctttatgag
     7381 tctggtggta ttaagattgt gaccaagacc tcaagcatgc ttgggtcaat gatggttggc
     7441 tccatgacag cttcaaatgt gaagtttaag accattttaa cagttgctgc aaagggagcc
     7501 aaggaagcag cctctatcca aaattatttg gatcagctct ttattggagt tgtccctctt
     7561 ttagtaacca tgaccgcctt ttggcttttg cgtaagaagg tgaacattaa ctggattatg
     7621 tttggcatta tgctattggg tattgttctt ggtcttttag gtatttgcta ataatctcct
     7681 agcatcaagg ataggtaagg cagggacttc ttgctttgct tatccttttt tgtagtgagg
     7741 gctgctgaaa tagccacctg cttgcttaaa tggcttatgg atttgttaga tagattaaga
     7801 ttttcttagc tttgagaaat gatttggtat aatagaagga aataagggaa aaggctgcct
     7861 atggaagaaa gatttaaaaa gcgattgcag gatgatattt cacatcattt ttcacaccaa
     7921 tcattgattt tgtccatttt actgattgga ctctttctca ttttttcatt ggcacctcag
     7981 caaattgggc tgtatcaaga tttgaaggct gttgaacata gctatcacca gctgattcgg
     8041 caaaataagg cgcttttaac ggagctcaat cagcatattc tgaccaaatt tgtgaatcat
     8101 cagctgagct cttctgacct tagcaaacaa tattatcacc taagaaaccg ctcacaaagc
     8161 caatcagagc tgctggtttt tgatgctaac agtcacatgc tgtttgctag taatcagcat
     8221 ctgggaaatt tttttcgcaa tgctgtctat atgacagaag tcttaaaaaa agcaaggcaa
     8281 aggagtagct tcttgaggat cagtatggat aatgaggagg ggcattattt actgctgata
     8341 aagcctatta agatagatca tcaggttaag ggctattcgc ttcttgtgat gaatggtaag
     8401 gattttcttc agctatcaca tcagattgct tcagattttg tgattgcaga tcagtttgac
     8461 aatagctttg cctttaccaa tcggaccttt atgacctcaa gtctgaataa gcttgacagt
     8521 cattttctta agggctattt tatctttcac gagcatcgtg cctttatcct aagaaaggtc
     8581 gctcttagtc cttctatcac tctttacagc taccgccctt tgattccagt ttctattgca
     8641 ctcttgtttt cattgatgtc ctctgtcatg atttatgcta ttttgtattg gaagtctaag
     8701 gctctggcga cgcagattgc ttctagcaat tcagcagcga tcaatcagat gattcttgat
     8761 atgcaggcca tctcaaggca ggaaaaaaat gccattgacc tgcaaagtca agatgaattt
     8821 caatacctgt cggttcagat caatcagatg attagccgat tgcaggcact tcatcagaag
     8881 accctagcct tagaaaagca aaatgtgagt tttgaaaaac gcatgctgga agcccaattt
     8941 aaccctcatt ttctctataa tacacttgaa acaattttga ttacaagtca ttatgacagt
     9001 gacctcacag aaaaaattgt ccttcagcta accaggctgc ttcgctatag cttagacgaa
     9061 tcacaggagg ctgtgtgtct gggagaggat ttggctgtct tagaatccta tctgttgatt
     9121 agccagatta ggtttgaaga gctgcgctac acgatagctg ttgaaccagc cctagagacc
     9181 ctaagggttc ccaaattatt tttattgcca ttgattgaaa atgcgatcaa atatggtctg
     9241 cgctatcgcc atgaccttgt gattgagatc agcgtgagac agcttgctga tggaatttac
     9301 tttactgtag cagataacgg tcctggaatt agtcaaaaaa ggcaggccga tattaaagag
     9361 ctcttgcatt cagaggattc acatcatggc ttggtcaatt cttatcgtcg actcaagcat
     9421 caatttataa aagttgaatt gatcttttgt caaagagatg agcgcttttt actaacctat
     9481 atggttaagg agtaacagat gtataagcta ctaattgttg aagatgagca tattattcgc
     9541 aaatggcttc gttatgcgat tgattatcat gcgctcaata tccttgttat cggagaagct
     9601 aaggacggtc agcagggggc taagctgatt gcagaggcta agccagatat tgttttgaca
     9661 gacattaaca tgccgattat gactgccttt gagatgtttg aggccacaaa agagcagtcc
     9721 tatgctaaaa tcattttgtc tggctatgct gatttcgcta atgcaaagtc tgctatccat
     9781 tatggtgtgc ttgagttttt gaccaagccc ttggaaaggc aggccttaca tgattgcttg
     9841 ctaactatta tccaaaagct gcaacagcag tctcaagagc aggagctaag ccagcagcag
     9901 gattacctca aactgccaca gcctaatgac caattgcctg atgttgtcca agaaatgctc
     9961 agctggatcc atgagcatta ccaggataaa atcatgattg gtcagttggc tcacgatctg
    10021 ggctatagcg aaagtcacct ctatcattta gctaaaaaat acctgaaaat gacttttagt
    10081 gactatatca accaataccg cctgaatcga gcaattcaat tgctgattgc tgagccggat
    10141 gtgatggttt atcagcttgc agaggctgtt ggcatttatg actaccgcta ttttgatcgt
    10201 gtgttcaaaa aatatttagg acaaacggtc aaggatttca gagaaacggt attacaccag
    10261 agatcagata ggagttcatt gtgacaagaa aaaagctgct attagcaatg gcaatagtga
    10321 tactaggtgt gattggctct ggcttgtatg ctatctggag gcatcaagca ggaccagctc
    10381 ccagcaaacc aagagaattg gttgttttga cacccaacag tcaaaatatc ctaacaggta
    10441 cgatcccagc ctttgaagaa aaatacggca ttaaaatccg tctgattcaa ggaggcacag
    10501 gccagctcat tgatcgcttg caaaaggaca aggaccagct ccatgcagac atcttttttg
    10561 gggggaatta cacacaattt gagagtcata aggagctatt tgagccttac ctttcaaagc
    10621 atattggctt tgtattgcct gattacctgc tgcaaagcga ggtcgcaacc ccctatacgc
    10681 ttaatggaag tgttctcatt gtgaataatg aattggcaaa ggacatggtt attaccagct
    10741 atgaggattt gctaaagcca gagctaaagg gaaagattgc ttttgcagac cccaacacct
    10801 cctctagtgc cttttctcag ctgaccaata ttctcttagc caaggggggc tacactaacc
    10861 ccaaggcttg gagctatatc aagcagttga ttcatagcat gaattcaatc aaatctgcta
    10921 gctcatcaga tgtttatcag tcagtagcag aaggaaagat gaccgtcggt cttacctatg
    10981 aggacccctg tgttaacctt ttaaagagtg gtgccaacgt ttctattgtg tatccaaagg
    11041 agggaacggt ttttttaccc tcagcagttg ccattgttaa gcaatctaag gccaaggctg
    11101 atgccaaatt gtttattaat tatatgttgt ctttagatgt gcagcgggtc tttggtcaat
    11161 caaccagtaa taggccaatt cgaaaggacg ctaaggccag tcaagacatg aagcctttag
    11221 atgacattat cacgctaaag gaagactatg attatatcac aagacataaa aaggatattt
    11281 tagaacgata caatcaattg agaaagacca ctgactaaat ggctttgtta tatgaaacag
    11341 ttcatgctgt gctgcacctg aatcgttagc tgctttgtct agctttttga ggtcaatctc
    11401 tgcttgggct gttttttatg ttaccataac ccactgcatt tgtttagaaa gtcaagcgag
    11461 atcttaatag ccagttataa taggtctttg agagggagtc tgagcttgct tgaggtggca
    11521 agaagatctg ttttgacgtc aaatggctga atttttggta aaatgatagc atgaatgaac
    11581 tgataaaaca caagctagag cttttgccag atagtcctgg ctgttatttg cataaggata
    11641 aggctggcac tattatttat gttggcaagg ccaaaaatct gagaaatcgc gtacgctctt
    11701 attttcgagg aagccatgat accaagacag agctgttagt ttctgaaata gctgattttg
    11761 agtttattgt cacaggatca aatacagaag cactcttatt ggaaatcaat ttgattcaag
    11821 agaacatgcc caagtacaat atcaagctaa aggacgacaa gtcttatccc tttatcaaga
    11881 tcactaacga gccatttcca agactattaa tcacacgtca gattaaaaaa aatgacggcc
    11941 tgtattttgg tccctaccca gatgcttaca ctgccactga ggttaaaaag ctgctagacc
    12001 gtatttttcc ctttaaaaaa tgcaaaaacc ctgttaacaa ggtctgcttt tactatcatt
    12061 tagggcaatg tcaggctcac acgatttgcc atacagacaa ggcttattgg gacagcttgg
    12121 ttgctgatgt caagcagttt ttaaacggta aggacgacaa gatcattgat gatttgcgct
    12181 ccaagatgct tgaagcttcg cacaatcaag aatttgaacg ggcagctgaa tatcgtgatt
    12241 tgatttcagg tattgccacc atgcgaacca agcaaagggt gatgagtaag gacttgcagg
    12301 atagggatat ttttggctat tttgttgata agggctggat gtgtgtgcag gtcttttttg
    12361 tccgtcaggg taagctcatt cagcgagatg tgaatatgtt tccttattac aacgaagctg
    12421 aagaggattt tttgacctat gtcgggcaat tttatagcga ccaacggcat ttgatcccta
    12481 aggaggtctt tattccagag acgattgatg agaccttggt tgcagccatt gttccagcaa
    12541 ggattgtcaa gccgcagcga ggggaaaaaa agcagctggt cgccttagca actaagaatg
    12601 ctcgggttag ccttcagcaa aaatttgatt tgctggaaaa ggatttaaga aaaacaagtg
    12661 gtgctattga gcatcttggt cagctgttag gcattgaaaa gcctgttcgt attgaggcct
    12721 ttgacaattc aaacattcag ggcacaagtc cggtagctgc gatggtggtt tttgtcgatg
    12781 ggaagcccag caagaaggac tatcgcaaat ttaaaatcaa aacagtgatt ggtccagatg
    12841 attatgcgag catgagagag gtgatttatc gtcgttatag ccgcgtgaag catgaagggc
    12901 tacaggcacc tgatttgatt attgttgatg gtgggcaggg tcaggtcaag gctgctcgtg
    12961 atgtgattga gcaccagcta ggccttagca ttccagtagc tggtctgcaa aaaaatgaca
    13021 agcaccagac ccatgaattg ctttttggta accccttggc agtggttgag ctgccgagaa
    13081 attcagaaga gttttttctg ctgcatcgta tacaagatga ggttcatcgc tttgccatta
    13141 cctttcacag gcaggtcagg agtaaaaatg ccttttcatc aaagctagat cacattgcag
    13201 gcttagggcc aaaacgcaaa cagctactac tcaagcgatt taaaagcatg actgctcttg
    13261 aacaggctag tcttgaagaa attcagcagc tagggattcc aaaaacagtc gctgaggcac
    13321 tgtttgatca ccttacctca aaaagtgagg tctgaattgg ccttgtcagg agctcaagca
    13381 gtctgaattt tcttgacaaa agtgaaaaaa tagctgaaac cagtttcaaa aaatgataga
    13441 atgatactac aacataaaag aattagatag gaagcatttg cagtgaaatt tctcgaatta
    13501 aacaaaaaac gccatgctat taaacggttt aacgataagc ccgttgatta taatgacttg
    13561 cgaacagcta ttgaggttgc cactctggca ccaagtgcta acaatattca gccttggaaa
    13621 tttgtcattg ttgaggaaaa aaaggcagag ctggcaaagg atctgccgtt ggctaataag
    13681 actcaggtag agcaggctca gtatgttatt gccctgtttt ctgataccga cctcattcag
    13741 cgctctcgta agattgcccg cattggggtc aagtccttgc ctgataactt gattggttat
    13801 tacatggaga ccctgccgcc acgttttgct acctttactg agacccaaaa aggcgaatat
    13861 ctggccatta atgctggctt ggtggcgatg aatttggtcc ttgccttaac ggatcagaaa
    13921 atggcctcaa atattatttt aggctttaat aaaaagctaa ctaatgagat tttagatatt
    13981 gatccacgct ttcgtcctga attattgata actgtggggt atagcgatga caagccagag
    14041 cctagctatc gcctaccagt agacgaaatc attgaaagac gctaagatac acaactactc
    14101 gtccagctag cctataagtt tttggattta ggaggatagc gaggcaacac ataaaggaga
    14161 aaaagatgac aacaattgat tttaaagcag aggttgataa gcgcaaggaa gctatgctag
    14221 aggatctatc aaacctatta agcattaatt ccgagcgaga cgatgctaag gcagatgcca
    14281 agcacccatt tggtcctggt ccggttaagg ccttggagtt ctttcttgcc atggcagagc
    14341 gtgatggtta ccaaacgcgt aatattgata actatgctgg tgattttgaa tttggtcagg
    14401 gagatgaggt tttagggatt tttgcccatt tagacgtggt acctgctggt agtggctggg
    14461 agacagaccc ttataagccg gtgattaagg ataatcgtat ctatgcgcgt ggttcatctg
    14521 atgataaggg gccaaccatg gcttgctatt atgccctgaa aatcatcaag gaattaggct
    14581 tgccagtttc taaaagggtt cgcttcattg ttgggactga tgaggagtca ggctggggtg
    14641 atatggacta ttattttgct cacaatggct tgaagaaccc tgattttggt ttttcaccag
    14701 atgctgaatt tcccattatc aatggtgaga aaggaaacat tacagaatac cttcattttg
    14761 ttggtcaaaa tgctggagct tttgtccttc atcgcttcca aggcggttta cgtgaaaata
    14821 tggttcctga atcagcgaca gctctgatca gctcaccgca tgagcttaat gttatcgaag
    14881 cttctttgga gcaattctta tctgagcacg cagtgacagg atctgtcaaa gaggctgatg
    14941 ggctattgga agtgaccatt attgggaaat ctgctcatgg ctctacacca gaggctggtg
    15001 ttaacggtgc aaccctgctg gctaaattct taaatcaatt tagctttgat ggcgcagcca
    15061 aggcttattt gcatattgca ggtgaggtgc ttcatgagga tttcacagca gaaaagcttg
    15121 gcttggctta tacagatgac aaaatgggtg cccttagcat gaatgcaggt gtctttagct
    15181 ttgctaagga ttcagatgac aataccattg ccttgaattt ccgttatcca aagggaacca
    15241 atgcagcagt gctaaaggca gggcttgagc aattaccagg cttgactaag gttaccttat
    15301 ctgagcatga acacacccct cactatgtgc caatggacga tgagctggtc tcaaccctcc
    15361 tatccgtcta tgaaaagcaa acaggactca agggctacga gcaggttatc ggtggtggca
    15421 cctttggacg cttgcttgag cgtggtgttg cctttggtgc gatgttccca ggtgatgaaa
    15481 acacaatgca tcaggccaat gaatacatgc cattagacaa tatttaccga tcagctgcca
    15541 tttacgccga agctatttat gaattgatca aataagagat tgaacaagct ctctgtctaa
    15601 gatgagcctt gctaatatta acgaataaaa gccttatgaa gttagtcgtt taatgagact
    15661 tcataaggct ttttgtttgg cgtcaagcca ttatttacaa agagaaatgc cacagtggat
    15721 catcttttga aaagtccttg taaaaacaga cgtaaaacta gttttagagg agacattgat
    15781 aggcagtcat gcttatcaag agatcttgtc tagcagttat ggcaaaaaga tcagtgaact
    15841 attattttcc aaggcagaac tgactgaaca attgagtaat taattcatca ggtgcggcat
    15901 cgcctgtgat ttctcctagg atttcccaag ctctggtcaa atcaatctgt aagagatcaa
    15961 ccggcattcc taaagcaagt ccttcattga cagcctctaa gctttgtact gcctgctcaa
    16021 tcaaggaaat atgacgagca ttggataggt aagtcgcatc ttgctctatt agcccagtat
    16081 gatcaaagaa aatctgattg atccggtctt cgatcaggtc aatgttttgg ttttgcaaaa
    16141 ctgatattgg gatcgcctct tctggaagct ggtctttttc aatgacctgc tccagatcgg
    16201 ttttattgag gagaataatg cgattgctat cctgactaag ggctagcaga gccttgtcct
    16261 gttcggtcag cttttccgaa gcattgagaa ctaaaaggac cagatcagcc tcctgtaggg
    16321 cttttttaga ccgctcaaca ccaatttgct ctactaaatc atctgtttct ctaattccag
    16381 cagtatcaac tagctttaga ggaattccct tgatattgac atattcttca atgacatcac
    16441 gagttgttcc tgcaatatca gtgacaatgg ccttatcctc acgtaacaag gtattgagca
    16501 gactagactt tcctacattc ggtcggccga taatagctgt tgacaagccc tcacgtagga
    16561 tcttcccgcg cttggcagta cgtaggagct gctctaaaag tgtttgaaat tctcgcgttt
    16621 tgtcacgcaa aagagcagtg gtcatttctt cgacatcatc atattcgggg tagtcgatat
    16681 taacctcaac ctgggctaag gtatttagga tttcttgacg tgtgtcgctg atgagctgtg
    16741 atagggagcc gtctagctgc ttgatagcaa tagacatggc cttatcagtc tttgcacgaa
    16801 tcagatccat gactgcctca gcctgtgtta aatcaatacg gccatttaaa aaagcacgct
    16861 ttgtaaattc gccgggctct gccattcgag ctccctgttt aatgaggagc tgtaaaatgt
    16921 catttgtcac cgcaataccg ccatgggtat tgatttcaat cacgtcctct ctggtaaagg
    16981 tttttggcgc caacatgact gataccatga cctcatcaat cacttcacct gtgcttggct
    17041 tgataatatg accatagtta agggtatgtg aggcgactgt tgttagatct tttcctttaa
    17101 agatcgattt agcaatgtcc agagccttgg taccagacaa gcgaacaatg ccaatagctc
    17161 cttcacctaa cggagttgaa atggctgcaa ttgtatcaaa ttctttagtt atactcatgc
    17221 cttctattgt agaacaagtc agcatagaaa gcaaggtatt gcattagctg ctcgttgtcg
    17281 tcattcttgt ctagtggcaa agcctcaaaa gcagttgtaa acagctaaag ctatgattaa
    17341 aaagccttgt atggtaagta caggataaag ccaaaaagct gatgagtttt agataaacat
    17401 acaggctcga aaagccctat taaaccgaca gcaacaatcc tcacacagta tagttgactt
    17461 aactacctga tgtcatttct ggctgttttt ataatgacaa tggcaatatc ggttattttg
    17521 actatgctgg gtgcttgtat cctagtggac tgactgacaa tcagggcttc tttttcaacc
    17581 acgaaaacat taaaaaagtc tggtttggag gctatattga cgatagtgaa agagaagctc
    17641 aagacttttt taaaaaagag gcaggctata ttaaatatcc taaacttagt atagataata
    17701 gcactagata gcattaattt aagtatataa cgttatgatt atggttggat tagttcatta
    17761 tacactagca ataaggtaga ttattttgtt ataataaaat atatacaatt attagagagt
    17821 tagaaagagt tatatggtag tattacaaaa taatagtagc acagctagtg agcgagcgac
    17881 agctttggca agaggagtcc aggccctctc tagtgctggt gcggtgagca aagatatgaa
    17941 gacgaccgtt actggaaatc gtagtgatgc cagctctgcc attgatttat cgcacaacgt
    18001 ttcagcgcag gtagttggga tcatcgcttc tatgtcgcaa cacattcaga gtgtctctgc
    18061 ctcttttcaa gcgatggatc ttcagcttgg aaaagagtta gggcgtttag aaaacaggcg
    18121 gaggtttagt ctcaatgacc caaaatgagc tcatgtacca gaaggagaga ttggataaac
    18181 gcttggaaac catagcccaa gagcttaagc gtaatgaaca gcgctttgaa gactatgagg
    18241 aactatctaa cctagcggca caactgttaa cagcagctgc aaccaccttt cgttcatcat
    18301 cagatagtca tctctttgaa ggggctttgg cagaagaatg ttatttgaaa aggaaaacac
    18361 aagcgtcctt ggaacaaagt catgaggagc tcttaggaga gcagcgtcgt ttgtaccaag
    18421 aagaggaagc ccttacccga caattaaagc tagtcaaagg aaaggagaga gctaatgagc
    18481 attgacatgt atctggggtc atcggaccag caagctagta gcgttggtaa ggtcttgcag
    18541 cagcggataa cagcttataa gtctttgcaa agagctttgg agcaattggt gtcttctagt
    18601 cctgacttat cagggcatac ctatgcttct gctaaaaggt acagcgagca ggtattgatc
    18661 cctttgatga ggggctgtat cctgctagat gaagccatca aggaagcctg tgcagcattt
    18721 cctaatgact accgtcgtca ggttgatagt gtggatttga aggagagtga gctggtggat
    18781 cagatcagcc gctcagaccg catcataggt cgttacgttg agttgattga tctggagtat
    18841 cggcaggagc tgccgaatta ctcttatatt actaatctca agagcggagc gagtaaccag
    18901 cgtcaagtca agagaaaatt agaagagaag ctccttaagc tgcgagagtt tgatagcaat
    18961 tcccgtcacc tcttttcgtc tatcgcagcc ttagccgagg cagtcaatat aggtatcaga
    19021 caaaccaaga cctcttggaa tgggacaagt cagacgttca ctcttcccag ggctcttgac
    19081 ttagagtgga ccaaggtagt agaaaagagg tggacgcaaa gggaggaaaa agcctcgaag
    19141 ctgaagctac agcaggcagc agaaaaactt tcgagagaaa ccgggattaa gtacgaagat
    19201 gcctatcgtt ttgtgatgga cggtgttctg tcagatgaaa ataagaacaa aatcaagagt
    19261 gtaaagaaac tagttaagta tacaaagggt gggctgtata tcgtttcctc aggaaggtat
    19321 tattggaaac attcaggtaa acattattgg aaaaatacac caaacaaaac atggaatatt
    19381 tggaaagcat ctaaaaacga tcccaatttt gacaaaggag ggatcaaagg taaacatttt
    19441 tctaaaaaag gagcccgtta cacagactta cctggtatca agcaattgaa gaagagtgaa
    19501 acagtacaat ccctcatttc aaaaatttca aaagataatc aagggaagct caccaaagtt
    19561 ggtaaagggt taaagaaagt tgataaagag ctaagcaaca tatcgtcaaa actcaagtca
    19621 tatgagcatg gacgcctaaa tagagacttg aaaatgatga aggagaataa cctgggtaaa
    19681 agtctcggta agtttgggaa agttggaaaa gctgcaagca aggtgctcaa gtttgcagga
    19741 aaaggtctca aagttgcggg ttgggtaggt gctgctataa atgttaagga ctcggttgaa
    19801 acttacaaga aaaaaggcta tagcaatgag caaactgctg ctttaacagc ccgtaaggta
    19861 gctgttgata ctgcaacaac tgttgtcgga agcaatattg ggcgtgtaac aggtgcagtt
    19921 attggtcaag cagttatacc tattccaggt gtaggtgctg ctatcggttc tgttgcagga
    19981 agtattttag gagctatggc aggtagttgg attggtagta caattaatga caatttagat
    20041 aagaacgtaa aacctaaaca atcaggaagg agtttagcat ggtaatgtta atgagaacac
    20101 tgttatttcc agttgataac ggacttgatt caggattgac tggtgatggt tatgcagctg
    20161 agtatgattt gtggactgga aaggtcacgt ggcgacaact tggtgatgga aaaataaaaa
    20221 ggcaacaaaa ggtagcagct ataattaatc tcattgcagc tgcaatatct ccacttgtca
    20281 tcatgtctat catttttacg gcaaaaagtc tgaagctttt tgatgtagat actagtacaa
    20341 caatttatcg atatgctcct ctgatggtag gcttggtctt tttcttctcg tttgaattat
    20401 tgatgctggc tattagacgt ctgtatccat tagccaaaga ggagccaagt ttaaagcgtc
    20461 aacatgggta ttttaagacc atgtatgaca atactatacg tgagaatgat ggtgttttta
    20521 ataatttatc agtacctttt atagggcttt atgtagcttt cttgattgcc ttttcggtta
    20581 ttccaatttt ttactctcaa tatctgcagc aaaattcttt ttggtcctat ttaggaaatt
    20641 tagtaggaag tagcattctt atttccttag tccccaattt tttatggaat gtcttagtga
    20701 aacaattgat ttacatcaag cttattcgca aaacgaaaga aaaaatctta aagaatgaaa
    20761 cctaaacaat caggaaggag tttagcatgg taatgttaat gagaaccttg ttatttccca
    20821 tagataatgg tatggataat aacttaattg gagacggctt atcagctgag tatgacctat
    20881 ggactggaaa agttacgtgg cgtcagccca gtgatgataa gattagaacc caacaaaagg
    20941 tagcatttgt acttaatctt atagctggta gtttatctcc attagctata tttttatttg
    21001 ttattattgt tagacgctta ggcgttttta gtggcgatac taattcaatg attttcaagt
    21061 gggcaccgct aatagttgga tttatccttt ttatatcgtt tgaattattg atgttggcgc
    21121 ttagaagtag atatacgata ttagagaaag agcccgattt agatcgtcaa ctatactatt
    21181 atcgtacaat gtatgataat actatacatg acaattcagg tgtttttaac aatttatcag
    21241 taccttatgt aggtctatac attactttat ttctaatttt tttaatcatt ccactttgtt
    21301 atcattttta cttgcaccca tcttcatttg gggattatct cgctgcatta tctgtaacaa
    21361 gtttgttgat ttccttattt cccaattttt tatggaatgg tgtcttgaag cacgttatat
    21421 atgtcaaact tattcgccaa acaaaagaaa gaattttaaa gaatgaaacc taaacaatca
    21481 ggaaggagct tagcatggta atgttaatga gaacgctgtt attcccagtt gataatggca
    21541 tgggaacggg cttgaccggt gatggttatg cggctgagta tgatctatgg actggaaagg
    21601 tcacgtggcg acaagccacc aaacaaacaa ttgaaaagca acaagcacta acgtctaacc
    21661 ttttgattat tgcctcatgc ttatcaccag ttactgttgc aggaatgata ctgttgagta
    21721 gaagtttccc tattttcgag gaagacttat cagagaaaat tgatacttat gctccaatta
    21781 ttcttggtgt tgtgttattt cttgcttttg agacgttaat gcttgctatc agaggtcgtg
    21841 atccattagc ggagaaggaa ccagatttaa agcggcagca tgactatttt gaaaagatgt
    21901 ttgattttgc tattcgtaga aatttgtcgt cagataatct aaaaactcct tatatagcta
    21961 cttattttgc ttttggtatt tctttactct gtattccatt tagctattat gtttatctga
    22021 atccggagca attccctaat ttggattatg gtcatttatc aatcctgctt gtaacaagta
    22081 ttcttatttc cctagttccc aactttttat ggaatgttct attaaagcac attatctata
    22141 tcaagcttat tcgcaaaacg aaaggacaat aaaacattat gaacaaacca gaacacattt
    22201 taccgattgg tactatagtg ctgacggaga caggagaaat tcctttgatg attgtgagtc
    22261 gtgcctctct ttttgatgat aatggagaaa tcggctattt tgattatgct gcagttcctt
    22321 atccagaagg cataggaaat gataatgagt accttttctt caaccatgag gatattgctg
    22381 atgtcatcta ttttgggtat gtcaattcca atgaacagct ttttgcagaa gcctacgatg
    22441 atttggtgaa aacatcaggt tatcgtaaat taagcttaga tcaccatcaa tagaaaaagg
    22501 acatgaagat tatctagaaa aagaaaagaa ctaatgagca ttgacatgta tctggggtca
    22561 tcgaaccagc aggctaatga tgtatggcca atattttgag aggatcggcc tgctcctctt
    22621 ttttgtatgt tcaaagctat aaaaagctta ctttttgagg tataaagctt cgacaatcaa
    22681 gagtatttgc tctggtggct ttaatgatct tgcttatagc ttctggtcag attgttttag
    22741 cctgcttgtg ctgtctgatc cagatttgac tgaggctttg atgacagtcg tgaaggcggg
    22801 tttaagaatg gcatgtctaa tgtcaattta caatagagaa ggaaaattga tcaaacagtg
    22861 tgagatatta ttaacaagtt tgcgctttca tggtataata aagtgctagg aagcatttta
    22921 ttataagata agggggaatc atggaagcac tgaaaaagat tgccggtgtg actgctgcgc
    22981 aatatgtaac agatggaatg accattggat taggaacagg atcaacagct tattactttg
    23041 ttgaagaaat tggtcgtcgc atcaaggaag agggactaca ggttgttggt gtgacaacct
    23101 caagtgtaac aaccaagcaa gcagagggcc taggtattcc cttaacatca attgatgata
    23161 ttgactgcat tgacctgact gttgatggtg ctgatgaggt ggataaggcc tttaacggta
    23221 ttaagggtgg tggagcagct ctattgatgg agaaaattgt tgcaacacca accaaggaat
    23281 acatctgggt tgttgatgaa tcaaagctgg tggatcattt aggtgctttc aagctccctg
    23341 ttgaggtcgt tcaatacggt gctgataggc tatttcgagt ctttgaaagg gctggctata
    23401 agccctcttt tcgcatgaag ggggataagc gtctcataac ggatatgcag aactttatca
    23461 ttgatcttaa ccttggctgt atcgaaaatc cttgtgagtt tgggcgtctg ctggatcaaa
    23521 ctgttggtgt tgtcgagcat ggccttttca atggtatggt tgataaggtc attgttgctg
    23581 gtcaggctgg tgtaacggtc cttgaagcta atcagtcaac ctaattccta gctcaatcat
    23641 gttttacatt attttatagg ttttggggag ccaaccgtaa cctcccctag attggagact
    23701 tatgtcaaaa tttaatcgta ttcacttagt cgttctagat tctgttggta ttggtgcagc
    23761 accagatgcc gacaaattct ttaatgctgg tgtagctgat acagattctg acaccctcgg
    23821 tcatatttca gagacagctg gtctggctgt tccaaatatg gcaaaaattg gacttggtca
    23881 tattcctcgt cctgtccccc taaagacagt tccagctgag gctgatccta ctggctatgt
    23941 caccaaatta gaagaggtat ctcttggtaa ggataccatg acaggtcact gggaaattat
    24001 gggcttaaac attactgagc catttgatac cttctgggat ggctttccag aggagattat
    24061 ccaaaaaatc gaagcttttt caggccgtaa ggtcattcgt gaagccaata agccttactc
    24121 agggacaaag gtgattgatg attttggtcc ccgtcaaatg gaaactggtg agctgattgt
    24181 ttatacctct gccgaccctg tattgcaaat tgcagcacat gaggaggtga ttcctgttga
    24241 ggagctttac cggatttgtg agtatgcgcg ttccattacc cttgagcgtc ctgctctttt
    24301 aggtcgtatt attgcccgtc cgtatatagg agagccaggc agcttcactc gcacagctaa
    24361 tcgtcgtgat tatgcagtct caccgttcca agacactgtc ttaaataagc tggctgacgc
    24421 tgggatttct acttatgctg ttgggaaaat caatgacatc tttaatggct cagggattac
    24481 caacgatatg gggcacaata agtctaacag tcatgggatt gataccctga tcaaaacctt
    24541 gcagttgcca gcatttacaa aaggtctttc ttttactaac ttggttgatt ttgatgctag
    24601 ctttggtcac cgtcgtgatc cagagggcta tcgtgactgt ttgcatgaat ttgatcgtcg
    24661 cctgccagag atcattgcca acatgaagga cgatgatctg ctcttgatta cagctgatca
    24721 tggcaatgac ccaacctatg ctggaactga ccacacacgt gagtatattc cattgcttgc
    24781 ttactcagcc tcctgcactg gagcaggtgt gattccacag ggacattttg ctgatatttc
    24841 agcgactatt gccgaaaact tcggtgtgga cactgctatg attggaacat cattcttagc
    24901 tgacttggta taggagtaag caaatatcat ttgataggcc aaggagcttg gcgtatcaaa
    24961 ttgaaaacca gcgctgtggt taggtctatt aataggcttg tggcaggttg tctagttctg
    25021 atgatcggtg tgatattagt tgatttattg gactttgcta cagcaaaaag ctcaagagaa
    25081 gtatgcttta tagtaaaaaa taaataagat aaagggagaa ataagatgac attacttgaa
    25141 aaaattcgtg aaacacaggc tttcctagaa agcaagggca ttgataagcc tgaatttggt
    25201 ctcattttag gctctggtct aggtgagctt gccaatgagg ttgagcaggc gattgtgatt
    25261 gattatgctg atattccaaa ctggggcaaa tcaacagttg ttggtcatgc tggaaaatta
    25321 gtttatggtg agctggctgg tcgtaaagta ttggcacttc aagggcgctt tcatttctat
    25381 gaaggtaatc caatggaggt tgtgaccttc ccggtacgtg tgatgaaggc tctgggctgc
    25441 catagcttgc tggtgacaaa tgcagcaggc ggtatcggct atggtcctgg gacgcttatg
    25501 ctaatcaatg accatattaa tatgacagga acaaacccgc tcattggtga aaacctagat
    25561 gaatttggcc cacgcttccc agatatgtct gatgcctata cagcagctta tcgtgagaca
    25621 gctcgctcag tagcagaaaa actaggctta gacctgcaag agggtgttta ccttggctgt
    25681 tcaggaccaa cctatgaaac accagctgag attcgtgcct ttaaggttat gggagcagat
    25741 gctgttggta tgtcaactgt tccagaggtt attatcgctg cccactcagg cttgaaggtg
    25801 cttggaattt cagcgattac aaactttgca gcgggcttcc aatcagagct taaccatgaa
    25861 gaggttgtag aggtaactga gcgtatcaag gaaaacttta aaggcttggt taaggctatt
    25921 ttggcagagc tttaaggctt gctcttagac tagcagtaac catgagcgac tgctagtact
    25981 ttgatcgata agacgaggaa aaataaggat tgggacatta gagtgatgac tgatatggaa
    26041 catacgataa gtattctttt agaagtttat gcttatagtc atgcctacaa aattgcaaga
    26101 actctgcctg atttttcccc caaggtactt tatttgcttg agcttttaaa ggaaagaaga
    26161 gagcttaacg ttgcttatgc ctttcaacat agggcggaaa ataggcttat tgaggataga
    26221 catcaggtta agcttttgtt aaatgaagct caagaggagg agcagactgc aaattacctg
    26281 cttgatttgg cagctaaggt caaaaacggt gagattattg attttgtaag gtcagtatcg
    26341 cctgtcttgt atcgtctctt tttgcggctg cttgagcagg ctgtcccaga tgttcaaagc
    26401 tatattattg ataccaagaa tgatcaatat gacacttgga attttaaggc gatggaaaaa
    26461 gccgataatg acctctttag gagctatctg gcacaaagac agccacgtca tgtgacgaca
    26521 cgcagcttgg ctgatttact tgttttatca gagcttccag ctgatattaa aagactagtg
    26581 gtagtcttaa ggcagtttga aaaatcagtc cgcaatcccc tagcacattt gatcaaaccc
    26641 tttgatgagg aggagctata tcggacaact catttttcct ctcaagcctt tctagatggt
    26701 ttgattcgct tagcagtttt ttctggtgtt aactatatca aagagccctt ctattttgat
    26761 gtcgttaatg ctgtcattga aaaggagctg ttagacagcg ccaagcctta gctatttgaa
    26821 agattagcaa taataaaaaa cctgaacgat ctgaacgagg cttctctaag ctagctatga
    26881 ctagtcagct tagagcctta gaacaggtct ttcaggtttt ttatgtttag ctagtgtggt
    26941 taattaatga ttgaagctaa tttcttctag caggtagtca ataaatcgct ctcccatttt
    27001 tgagaggtta gccttttcgt gcttgataaa gacaatctca atcacatcag ggacatctaa
    27061 gggaatagcg acaatctggt ctccatttag atttgtgttt aaaataccgc tggcaacggt
    27121 gtagccattt aagccaatca tgagattaaa tagagtagct cggtcactca ccacaataga
    27181 cttactgtga gggatatgtg ccatcatctc ctctgagaaa taaaaggaat tgtgaatccc
    27241 ctgatcatag cttagataag gaaaatcaag gagatcatca atggttaagc tggttttatt
    27301 tgccagagga ttggacttgc tgataaagat atgcggtgtg gttttaaata gggtggaaac
    27361 ggtcaaatga ttttcctcaa acagcttggt aaggacgtct cggttgtagt cattgataaa
    27421 caaaacgccg atttctgagc gaaaattttt cacatcgtca atgatttccc aggttcttgt
    27481 ttctcgcaag aaaagctcgt actgggtcat atcagcccgc tttaataaag agacaaaagc
    27541 attgacaaca aaggcgtaat gctgagagga aacactaaag agctcacgac tagtattgtg
    27601 atttttatag cgatcctcta gcagtgctgt ttgttcaata atttgtctgg cataagatag
    27661 aaactcaacc ccgtccttgg ttaaggtaat gcccttggga ttacgaatga aaatagtaat
    27721 gcccatctcc tgctctaatt ccttgacagc attagacaga ctgggctgcg tgataaataa
    27781 ttgcttagcg gcttcgttca tggaaccgca ttcaacaatc tttataatgt attgtagttg
    27841 ttggattctc atactgacag tctatcttaa atagtacaaa gaatcaagtg cctttattag
    27901 agcttaagac aaggtttcac aagcggtagc ctagcttgtg cggtgaagct agcttgatgc
    27961 tagtgttgta cccaggtaaa aaagagctgg caaataggca gttttatcgc tttttaccgc
    28021 ttatttttgg catgcctgtg ttttgataaa cggctggtct tgatcggtaa aaagtaatcg
    28081 tgataatatc agataatacc tatttttcca ttgctctttt aattttcttg tgttatatta
    28141 ataatattga tatatttaat gttttgagat aaagggtggt gatggtgtaa tatgactgga
    28201 caaagtagtc atcaggtatt aattcaaaag ctgttggtca gcactcacta tttgacatta
    28261 tttagagatg agctgaagct agttgagagg acaccatcta ttttgggaag tgagtttcct
    28321 gtctctcttg ttcaaacgga attaggtgat attatcacct tggtggatac cttaaataag
    28381 cagcagcgct tgattgagtc gaccttttgg tatgaggagt cagcctttaa gctcatgaac
    28441 aaggccttag atattgttga taattggata aaggggatag atggcttaat taagctctgc
    28501 cagtccaagg aggtctttca ggccattgtt ggtgataaaa gaacacgtgt ttttggtgtt
    28561 ttgattgatg ttttttcttc cctaaaaatt agcaccatgt cattgaagga atttgcagct
    28621 ccggctgctc tttgccatta gattaagctg ggctaagctt ggatagtggc tggttaagcc
    28681 tgcaagttgc ccctctcatg acaagtctag gctttattta gggtgagcag tgtgccaagg
    28741 gtgtattaag tgctggttgc tttgaagctt cgccttgcta ggttagctgt gagtgatgtc
    28801 acgataactg cgcgaaacag ttatttctga attataatac aggttaaagt aggtactttt
    28861 aatgtttttc ctattgtaaa atctatacaa aataggatat atttttgaaa tagctgaaca
    28921 ttaacgtaca gcaagcttta ttttcttgct aaaaatcttt tttatacctt tgtcgtgtga
    28981 gtaatgtcaa aaccctttga caagggctgt caaaaaagct ataatgattg agataagtta
    29041 cctttaagtg agtccagaga ggcgagcaag gtacacagga taagatgaga gggtttgctc
    29101 tcttgatttt cgtgtagcct cgcttctttg gaagtgaggc ttttatggtg tgactttcag
    29161 ttggtctcgt ggtaatgatt cataagacca ataaaccgct cgttagacgg gtgggcatga
    29221 tttgtttggg agtaccccaa gctgcataga aaggataggt tatgcgagaa gaacgcccta
    29281 ttattgcctt agattttcct tcctttgagg aggtcaagtc atttctgtcg ctgtttccag
    29341 ctgatgagag gctatacgtt aagattggta tggaactgta ttatgctgaa ggaccagata
    29401 ttgtccgtta tgtcaagtcc ttaggtcaca gtgtttttct ggatttgaag ctgcatgata
    29461 ttccaaatac agtcaaatca acgatggcag tcctatcaag gcttggtata gacatgacga
    29521 ctgtgcaggc tgctggaggt gtagagatgc ttagagcagc gcgtgagggc ttggggcagg
    29581 gtccgattct cattgcggtg acacagctaa catcaactag cgaagagcaa atgcgtgagg
    29641 atcaaaacat tcaatccacg ctgttagcat ctgtgcttca ctatgccaag cgtaccgctc
    29701 aggctaagct agatggcgtg gtttgctcag cccatgaggt caaggccatt aagtcagaag
    29761 taccagcagg ctttgtgtgt ttgacacctg ggattcgccc gacaggtgct gacatcggag
    29821 atcaaaagcg ggtgatgaca cctcatcaag ctagagctat cggaagtgac tatattgttc
    29881 ttggtcgtcc gatcactcag gctacagacc ctgtcaaggc ttatcaccag attaaggcag
    29941 agtggaaccg ttagcagcag gatcatcatg acacatatag ctggactatg acaccaagga
    30001 aaagaggaga aaaatgacac tagcagcaca aattgcaaca gatttacttg agattaaggc
    30061 cgtttaccta agaccaaagg agccctttac ttgggcgtca ggcattacat caccgattta
    30121 tacggacaat cggatcaccc tttcttatcc aaaaaccaga agcttgattg aaaatggctt
    30181 tgtggagacg attaaggcag tatttccaga ggttgaggtg attgctggca cagcaactgc
    30241 tggtattcca catggtgcta tcgttgcaga taagatggac ctgccttttg cctatatccg
    30301 cagcaagcca aaggatcatg gagcaggcaa ccaaatagaa gggcatgtgc gctgcgggca
    30361 aaaaatggtg attatcgagg atttgatttc aacaggtgga tcagttctgg aggcggcagc
    30421 ggcagctagt cgcgaaggtg ctgatgtact aggagtggtg gcaattttta cctatgaatt
    30481 gccagtagca agcatcaatt ttgaaaaggc agggctttcc ttggtgacct tgtctaatta
    30541 ttcagacctc attaaggtcg ctaaggccaa gggctatatt gatgctgatg gcttggccct
    30601 gttaaaaaga tttaaggagg atcaaaagca ttggcagcat gagagttaaa cagtgctgaa
    30661 aagctgctga catgctgact atgtcttaag gagagaaaaa atgacttaca aagatttact
    30721 tgagataggt gagaccagtt attatcagac ggatcgcttg acttactaca aaaatcctgt
    30781 ggtatctgag cgctattttg ataattacct tagctatcgt agcatgcctt ctttggctga
    30841 tttgaaaaag gacttggcct atgtggcaaa agagcagcag gattatccta gtcactacgc
    30901 ctttctcttt tttgctgaaa atgaagagct aagtacagac atgcgagctt atttgacaga
    30961 tcatcacttt agccttgaaa agcacctgat ctttaccaat gagctggcaa agcttcacct
    31021 aaaggagcgt gatatatcac cagtcactat tgaacagctc tcagaaacaa gcttttctgc
    31081 ctatctggct tacaaatatc aggctaattt ggcttatggt gaaacctatg ccaatcaatg
    31141 caaggctgat aatgaagcca atctattgac aaacggctca accatttatt tagccatcaa
    31201 ggaagggaag attatcggag atattacggc ttgggaatgt ggcgactata ttgaaatgga
    31261 cgatttcagt gtagatgagg cctatcgtgg tcgtggtatc ggtacagcct tacagcgtaa
    31321 ggccagtcaa ggctataaga aggtcattct catctcagaa gaagctaatc gcgccatgta
    31381 tgagcaccaa ggctatcagg aggttgctta ctactggaca gcgctaaaaa catcgactag
    31441 ataagtgata aagaaacaga ttataggatt gaaggtgtag gctcttatga gtatgactct
    31501 tcaatccttt ttttctgagc gcatttgcta atcataccta atgaataagt cgtagcctgt
    31561 ctagtggctc attttaatgg cgtcttgctc tgttttatga ttaaatatag agaaaaagct
    31621 attgttaggg catgcttgtt ggtctagcaa ggctgatgga tgataggata gggaattgat
    31681 gatttttaaa gatgcaacag aaatggcgca ggctgttcga gaaggtaggg tgagcccctc
    31741 agccttagtg agagacacaa ttaaaaaggc tcaagcactc aatcctgagt tgaatgctat
    31801 tacctcagag cgtttttcag aagctcttgc tgaggcagca gcaagggatt tttctggaaa
    31861 gccatttgct ggtgtgccta tttttctaaa ggatttaggg caggagcagg agggccaatt
    31921 ggccactgca ggatcagtgt tatttaagga ttatcgtgcc tcaaaaacgg attatgttgt
    31981 gcagcgacta gaggagctgg gctttattat tttaggaaga agcaatacac ctgaatttgg
    32041 ctttaaaaat attagtgata gtcgcttaca tggtccggta aatctgccac aggacaagag
    32101 ccgtaatgct ggtggttcat caggtggggc agcagctctt gtgtcctcag gaatcacctt
    32161 gctggctcct gctagtgacg gaggaggatc cattcggatt cctgcctcct ttaatggctt
    32221 gatcggttta aagccaagca gaggaagagt gcctgtgggg ccaggctctt atcgtggctg
    32281 gcagggggcg tctgttcatt ttgctctaac gaggtctatt cgagacacaa gtcgtcttct
    32341 ttatcacttg caggtttatc aggtagaaag cccttttcca ttagtgccat taaccaaaga
    32401 agagcttttt caccctttag acagaccctt aaggattgct ctttatgatc acatgataga
    32461 tggaactacc gcctctatag atgctcagac agctttaacc gaggcctgtc attttctaaa
    32521 agagatgggg catgaggttg tgcgattaga taagcttcct ctagatatac caaaggttat
    32581 gagggattac tacctgatga ctagtgttga gacagctgct atgtttgctg atagccaaga
    32641 agcccttggt cgtcaggtga ccaaagcaga tatggaggtc atgacctggg ctatctacca
    32701 agcgggtaag gatattcttg cttcggtcta ttctcaggcg ctgcagcgct gggaccatta
    32761 tagtgctgaa atggcaagct ttcatgagca gtatgatctt ttgctgacct ttaccgccaa
    32821 tacgcctgct ccaaagcatg gacagttcca gccaagcaag gagctaatag ataagctggc
    32881 taaggcggaa tgctacccct ccagtcagcg cctagcgcta gtagaagcca tgtttgagca
    32941 gagcttgttc ataacccctt acacagcttt ggcaaatctg acaggccaac cagctcttag
    33001 tttaccaacc tatgaaacgt ctgctggatt gccgatgggc attcaattga tagctgctaa
    33061 agggcgagaa gacttattgc tgggaatagc tagacagttt gaacgggctg gattgttaaa
    33121 gctacctggt taaatattat aaaacagagc taatctatta taggttagct tttttgttaa
    33181 atcgagcata tctagtctct tataagatta gtcaatgcta tactgtcatt aataatgaaa
    33241 aaggagttct tgatgaaaaa aggagttgct ttactttctg ttagcttggc gagcttgctg
    33301 ttagccgcct gtgggtcaca gccatcagct caaaaaacaa gctgggaaaa gattaaagat
    33361 aaaggtgttt taaaggttgc tacgcctgcg acctaccagc caacatcgta ctataatgat
    33421 gccaatgaat tggtcggcta tgaggttgac ctgatgaagg aaattgggaa acgccttgat
    33481 cttaaggtga agttcattga aacaggctat gatcaggctt ttacttcggt tgatagcggt
    33541 cgtgttgatg tttctctcaa taattttgac attacagcca agcggcaaaa aaaatacaac
    33601 atctcaacgc cttataagta tggtgttggg ggaatgattg ttcgtgctga tggcagctca
    33661 ggcataagca aggctgacct aagcgattgg aaagggaaaa aagcagctgg cgcctctggt
    33721 acagaataca tgaaggttgc caagaagcaa ggtgctgaat tagtcactta tgataatgtg
    33781 acgggtgatg tttacctgaa cgatgttgct aatggcagaa cagactttat tcccaatgat
    33841 tatcctgcac aaaagctttt tgtggattac atgaagtctc aaaatcctaa cctcaatgtc
    33901 aaaatgagtg atgtgctgta taatccgaca gcacagggca ttatcatgag taaaaaagat
    33961 gacaccctta agaaaaagat tgatgcggtc atcaaagaca tgaaacaaga tggcagcttg
    34021 aaaaccattt caaagacata ctatgctggt caggatttga cagttccttt tggtaaggac
    34081 aagaaaattc cagtcattga tgccagtgat gtggactagt gccttagaca aaggagctct
    34141 aaagcgatgc ttaatcttag attgatacta gagagcttgg gctttgtttt gtcaggtttg
    34201 ccctatacct taggcatttc ttttttaagc tttctaacag gccttttgct gggcttgctt
    34261 ttagcctttt taaggcgttc tactagtcac tttagtcatt atctggtcag gagctatgtg
    34321 tccataatgc gtggcgttcc tatgattgtg gtgctctttg tcctttattt tgggcttccc
    34381 tattatggct tagaactgtc tgccttgtta tgtgcctatt tgggcttttc actggttagt
    34441 gcagcctata tctctgaggt ctttcgtgcc tcgattgatg ctattgatca gggacaatgg
    34501 gaggcagcaa gggctttggg gctgccttat gtcagcattg tcaagcatgt gattctgcct
    34561 caggcctttc gtattgctat tccgccttta ggaaatgttg tgattgatat ggtcaaaagt
    34621 tcgtctttgg cagctatgat taccgttcct gatatttttc aaaaggctaa aattattggt
    34681 ggcagggagt gggattacat gtctatgtat atcttggttg cctttattta ttgggtgatt
    34741 gcctttttgc tggagcgctg tcagggcttt ttagaaaaga ggctgcgctt actctcttaa
    34801 aaaccgaata tttaccctag aaatattgta tttctagggt ttttatgata aaaatatgat
    34861 agactaaagt agcctaatca gttagttagc tttgtcaaga actgactggc tagagtgttg
    34921 gaggtaggat atggcagact ctattgtatt tcggaaaaat catatgattt caactcaggc
    34981 ctttgctcga gtgctggaag cctcagggat taaaagaccg actaaggacg aggctagatt
    35041 atcgcaaatg ctaaagcatt ccaattatct atggacagca tgggaaggtg acaagttagt
    35101 tggtgttgct agagccctta ctgactatgc ttatgtctgc tatatttctg acctagcagt
    35161 tgatcaggca tatcagggtc aagggatagg caagcaattg ctgtctttta tctcagagga
    35221 tcttggagat gctgttgctc ttgtattgct gtcagcacct tcggcgatgt cctattaccc
    35281 taagcttggc tttgaacaat cagacaaagc cttcattatt ccacgaaaac cgttttagag
    35341 aggtatctaa tgacacattc agcttggcat gatgagatta agcaagtgtt acctaaggat
    35401 tattatcggc gtatcaatcg ctttttagat gaggtctatg cgactggagt ggtttacccg
    35461 cccagagaca atgtgtttaa ggccttacag gtaacgccat tagaagagac aagagtgctt
    35521 attttagggc aggaccctta tcatggccct cttcaagctc agggactttc cttttcagtg
    35581 cctgactcca ttcctgctcc gccatctttg caaaatattt tggaggaatt agcagcagat
    35641 attggagtaa ggaatcatca cgatcttagc agctgggctg agcagggagt gttgctcttg
    35701 aatgcctgct tgaccgttcc agaaggacgc gccaatgggc atgcaggtct catctgggag
    35761 ccctttaccg atgcggttat aaaggtcttg aatgctaagg ataggcctgt tgtgtttatc
    35821 ctctggggag cctatgcgag aagaaagaag gccttgatta ctaatccgat tcaccatgtt
    35881 atcgaaagcc ctcaccctag ccctctgtca gcctatcgtg gcttttttgg cagcaagccc
    35941 ttttcaagag ctaacgccat tttagaaaaa gaaggcctag gacagattga ctggctgcgc
    36001 taggcattga ggcaggctat tatggctaag caggacgatt taccaataaa gtatccggct
    36061 ttggagactt gggtatacct agctaaatag agattgatga tatcagggat caagacagtt
    36121 acgtccgata tgtcaagcaa aacaaataat cactgcctag ataaatcaga aattgctagg
    36181 gttatgcttg attatcctga taagcagata agtagatttg acataggagg ggtcatgtta
    36241 ttaattaaaa atgggcgtgt gatggatcca aaatcacagc tagatcaggt ggcagatgtc
    36301 ttaattgata atggaaggat tttacggatt gctccagaca ttgagcatga tgaggtagag
    36361 cagatcgatg ccagtggact tgttgttgct cctggtttag tggatattca tgttcatttt
    36421 agagagccgg gtcaaacgca caaggaggac attcatacag gtgctctggc agcagctgct
    36481 ggtggggtga caacagtagt catgatggca aacaccaatc ctgttatatc agatacggaa
    36541 accttacagg ctgttctagc aagtgctgct aaagaaaaaa ttaacattta taccaatgct
    36601 agtgtgacca agcggttcaa tggccaagag ctaacagact ttaaagcgct cttagcagct
    36661 ggtgcggtca gtttttctga tgatggcatt cctttagaga gctccaaggt cttaaaggaa
    36721 gcattggatt tggctaaggc caacaagacc ttcattgccc tgcatgagga ggatccccaa
    36781 ttaaacggtg tccttggctt caatgagcat atcgctaagg atcattttca tttttgtggc
    36841 gctactggtg tggcagaata tagtatgatt gccagagatg tgatgattgc ctatgatcga
    36901 caagctcatg ttcatattca acatttatct aaggctgagt ctgttaaggt agttgccttt
    36961 gctcagcagt taggtgccaa ggtcacagcc gaggcaacac cgcagcattt ttctaaaaca
    37021 gaagaccttt tacggcttgc aggggcaaat gccaagatga atccgcctct aagaacagaa
    37081 caagatagat tagcagttat tgaggggctc aaatcaggtg tcatagctat tattgcaacg
    37141 gatcatgcac cacatcatcg tgatgaaaag gccgttgctg atctgaccaa ggcaccatct
    37201 ggaatgaccg gcttagaaac ctcattgtca ttaggcctga caaatcttgt ggagccgagc
    37261 catctttcat tgatggcgtt attagagaaa atgaccatta atccagcctc actatatagc
    37321 tttgatgctg gttatttggc tgagtctggc cctgctgatc ttgttatttt tgctgacaag
    37381 gaggagcgtt tggtaacaga agcctttgct tcaaaggcta gtaattcacc ttttattggc
    37441 gaaaccctaa agggagttgt gaaatacacc attgctaagg gacaaattgt ttatcaggca
    37501 gacaactaat caacacttaa aaagctgagc atctgatagt aactgatgct cagctttttg
    37561 atttagtgat ggcttgcggg ctgctgcttg cttaagttca agccccaagg aatgagattt
    37621 tcagattgct gcttgattcg cttcatatta tcctgatgcc ttaggataat gattgctgct
    37681 agcacaacga tggtaatggt taatagccaa tcgtagctag gcaataaaaa gtgggcggca
    37741 ggaaaagtca gaacgctaat cacagctact acagacgctg ttagactagc tagtgaaatc
    37801 atgctaaata aataaagcgt tagcacaaac acagccgcta aaaaaaggag atagagtggg
    37861 gcaaagccta gcaagacacc agcactggtt gcgactgcct ttcctccctt gaagccagcg
    37921 aaaataggaa aggtatgccc taggacagca aaaaagccaa tagtaattgg tgagatattg
    37981 ctagcgccaa ccaaaaccgg aagaagcgtg gcaagcgtgc ccttaaaaat atcaatcaat
    38041 aaggttgcag caccagcttt tagcccaaga atccgaaacg tattggtcgt accggtatta
    38101 cctgagccat gctcacgcag gttgatgtta tagaaatact gtccaatcca taagcctgtt
    38161 ggaatggagc caagtaaata tgctgtaaga attaatagga tcaatttcat aacatacatt
    38221 atatcataat gattgattta agcggaagca gttacaaaga attacgaaaa aatcttaaat
    38281 tattttgcaa aattctcaaa aaacctgtaa gataaaaaag atgaaaacgt ctggaggtca
    38341 acttggctaa gaaagaaata agcataacaa attataatga tgatgccatt caggtcctag
    38401 agggcttaga ggcagttcgt aaaagaccag ggatgtatat cggatcaacc gatgcaaccg
    38461 gacttcacca tttgatttgg gagattgtcg acaatgctgt tgacgaggcc ttatctggct
    38521 ttggaaatga gatcgatgtg acgctaaaca aggatggttc tgccaccatt tctgacagcg
    38581 gacgaggcat gccgaccgga cagcacgccc ttggtatacc aactgttcag gtcatcttta
    38641 ccatcttgca tgcaggtggt aaatttggtc aaggaggcta taaaacctca ggaggcctgc
    38701 atggtgtggg ctcttcagtt gtaaatgccc tatcgtcatg gctagaggtg gaaatcacga
    38761 gagacggagc ggtttacaag cagcgctttg aaaatggcgg taggccagtg acaggcttag
    38821 aaaaaatagc tacagctcca aaaagcaaat cagggacaag ggttactttc atgcctgatg
    38881 acaagatttt ttcgacaact gagttcaagt ggaatactat cgcagagcgt ctaaaggaat
    38941 ctgcttttct gctaaagacg gttaaaatga ccctgactga tctacgaggt gacgatccgg
    39001 tcgttgagga atttcattat gaaaatggtg ttcaggattt tgttgcctat ctcaatgagg
    39061 acaaggaaac cttgactcct gtgatttaca tggaagggca ggagcaggat tttcaggttg
    39121 aggtcgcttt gcaatacaat gatgggtttt cagataacat tttgtccttt gttaacaatg
    39181 ttaggacaaa ggacggtggc agccatgaaa ctggcttaaa atcagctatt acaaaggcca
    39241 tgaatgacta tgcccgcaaa accagcctac taaaggaaaa ggataaaaac ttggagggct
    39301 cagattatcg tgagggcttg tctgcagtgt tatcgatcct tgtaccagag cagcatttgc
    39361 aatttgaagg gcaaacaaag gacaagctag gaagcccact ggcaaggccg atcgttgaga
    39421 gcattgtatc agaaaagctg accttctttt tacttgaaaa tggtgagctg gcaggtcatt
    39481 tgattcgtaa ggctatcaag gcaagagacg cgcgtgaggc agccagaaga gcgcgtgatg
    39541 agtctcgaaa tggtaagaaa aacaaaaagg acaaggggct tctttctggg aaattaactc
    39601 cagcccagtc caaaaatcct aagaaaaacg agctgtacct agtcgagggg gactcagctg
    39661 gaggctcagc taagcagggc agggatcgta aatttcaggc aattctcccc ttacgtggta
    39721 aggttttgaa cacagaaaag gccaagatgg ctgatattct caaaaatgag gaaatcaata
    39781 caatggttta taccattggc gcaggtgttg gtgctgattt caatcttgat gatattaatt
    39841 acgacaagat tattatcatg accgatgctg atacggatgg ggctcatatt cagaccctgc
    39901 tgctgacctt tttctaccgt tatatgcggc cgctggttga agcaggacat gtctatattg
    39961 ccttgcctcc tctttataaa atgtcaaagg gtaaaggcaa atcggagaag gtttcctatg
    40021 cttggacaga tggtgagctg gaggatcttc gcaaggaatt tggtaaaggt gcaagtctcc
    40081 aacgctataa gggacttggg gagatgaatg ccgatcagct atgggaaacc acgatggacc
    40141 ctgacacacg aacccttatc cgagtgacga ttgatgacct ggctagggca gagcgacgcg
    40201 tttcagtcct catgggagac aaggctgccc cacgccgtca atggattgag gacaatgtca
    40261 cctttacctt ggaggaaaat acggtttttt aaggcatttt tcctaaggag ggttctaaaa
    40321 tatctcatat caaattgcta ttcatgtgct cagcattcat ttatcaagga ttgtaatcat
    40381 tgaggtaaca gtgatgaagc tagatatttg tcaacaaagc tacagtcttc agtggggagg
    40441 cacctattat tttgcattga cagattatcc caatatcaag gcttgggaac tggaaaagct
    40501 agcagccttt tgtgcctacg aaaaatggaa tcatcgtcaa acagacatta gctgtcagga
    40561 cagcaagctt cttgaagagg ttcatcaatt tcttgaagca catgcttgtg cctatctctt
    40621 taggcctagc tgtaaattgg tggcttcaac atttaacatc aatggagagg cagtctgttg
    40681 tccttattta agtcatacct gcactgtagc ggctgctcta agcattttta agacaggaag
    40741 gctattgtct gctgtaagag cttttggggt aacggcacag gagttggcta ggagtgatcg
    40801 aaatgctgct ggtgatcctg ctgattattt tcattatgtg atgcttggct ggtccaatac
    40861 gacctcaggc tatcgcttgg ctatggagag attgcttaat cgtatgccaa atgaaaagga
    40921 cttaagagag cattttgtac ccggagttag ctttcactat agctattctg atatttgtca
    40981 gatgaaaggc tatgtttttg atggctatca ccctgctaag atcaaagacg agcttagttt
    41041 ggaggaattg caggcttgca ttattcctaa aagctggcag cagcgctttg aagcaattat
    41101 tccaaaggcc ttacgctcaa gggttcatta cctagactat aaaggcgaag gcttggtcga
    41161 gtggtctgat agggtttatc agctgttaag agtgatcagt gacagctagc tgtaaatagg
    41221 ctagctttat actatttttt gaatataata gacaatctaa cagaaaggaa agctcagtga
    41281 gaggtctctt gctgggtgtg ggatggattt cctagaaact gctaatccta gcgatagggg
    41341 agcgtagcga gcccattctg aaagctcctg ccgtagtgaa aagaagataa tcgcttacga
    41401 ttatcttcga gggaaatttc gagccgaagt ctcgaaattt aggaatggaa ccgtaggttc
    41461 gcttctgtcc ccactaccta aaggaacttt caaaaaaaac taattaaaga aagagatatc
    41521 tttctgaaag aaacaaagaa aggaatgttc agctagttta ctaactgaac acgggactat
    41581 ttttcctaga aaaatcggta acctcctagt gtccaaggac acgtcgtcag ttccagcatt
    41641 ttttacggaa aaatttcgca agcgaaacgt ccctttgtat cttatgagta atattcaaaa
    41701 catgtccctt gaggacatca tgggagagcg ttttggacgc tactccaaat acatcattca
    41761 ggagcgagcg cttcctgata ttcgagatgg tctaaagcct gttcagcgcc gcattcttta
    41821 ttctatgaat aaggacggta atacctttga aaagggctac cgcaagtcag ccaagtctgt
    41881 tggtaatatc atgggcaatt tccacccgca tggagattct tcgatctatg acgctatggt
    41941 acgcatgagt caggattgga agaatcgtga aattcttgtg gaaatgcatg gcaataacgg
    42001 ctcgatggac ggtgatccac cggcagctat gcggtacact gaggcaagat tatctgaaat
    42061 tgctggttac ctgctacagg acatcgataa aaaaacagtg ccatttgctt ggaattttga
    42121 cgataccgaa aaagagccaa cagtattgcc agctgccttt ccaaatctat tggtcaatgg
    42181 ctcatcaggg atctcagcag gctatgctac agatattcca ccacataatt tgtcagaggt
    42241 gatcgatgct gttatttata tgattgacca cccaaatgcc aagctggata agttaatgga
    42301 gctattgccg ggtcctgatt ttccaacagg tggtattatc caaggagcag ccgaaattaa
    42361 aaaagcctac gaaacaggta agagccgcgt tgttgttcgc tccagaactg aaattgagga
    42421 tctaaaggga ggcaagcagc agatcattgt gaccgaactt ccttatgagg tcaataaagc
    42481 tgtcctagtt aaaaaaattg atgatgttcg ggttaataac aaggttccag acatagcaga
    42541 ggtgcgtgat gagtcagacc gtacagggct acgcattgct attgagctca aaaaagacgc
    42601 tgacagccaa accatcttga attatttgtt gaagtatacc gagcttcaag tcaattataa
    42661 ttttaatatg gttgcgattg atcattttac gcctcgtcag gttggattgc aaaaaatctt
    42721 atcaagctat atcgctcacc gcaaaagtat tattatcaag cgctctcagt ttgacaagga
    42781 aaaggctgaa aagagattgc atattgttga gggcttgata cgtgtcttat ctattttaga
    42841 tgagattatc gcgctgatcc gagcttctga caataaggct gacgccaagg aaaacctaaa
    42901 ggtcagctat gatttttcag aggaacaagc agaggctatc gtaaccttac agctttatcg
    42961 actgaccaat acagatattg ttaccctcca gcaggaagaa catgacctaa gagagctcat
    43021 cacaactctc tctgccatta ttggtgatga agcaaccatg tataacgtga tgaagcgtga
    43081 gctaagagag gtcaagaaaa agtttgcagg gccgcgttta tcagagctgc aggctgaaag
    43141 ccaagcgatt gaaattgatt ctgctagtct tattttggag gaagaaacct ttgtcagtgt
    43201 gactcaggga ggctatatca agcgaacaag ccctaggtca tttcacgcct caagccttga
    43261 ggaaattggt aagcgtgatg atgatcatct gatctttgtt aagcaggcta agacaacaga
    43321 ccacctgtta ctctttacta atttaggtaa tgttatttac cgtccggtct atgagctgac
    43381 tgacttgcgc tggaaggaca tcggggagca tttatcacag gctattgcta attttgctgc
    43441 tgatgagctg gtgatatatg ctgagttgat ccagtccttt gaagagggac tatatatctc
    43501 agtgacacag catggactga ttaaacggtt tgagcgcaag gagctgacgc cttggcgaac
    43561 ctacaaatca aaatcaatta aatacgccaa gctaaaagac atagatgatc gcattgtggc
    43621 aatagcacca attatcatgg aagatcttct tttggtgacg cagcagggct acgccttgcg
    43681 gttttctagc caagaaatac cgattcaggg cctaaaggct gccggagtta aaggaattaa
    43741 cctaaaggct caggattact tggtttctgc ctgcccagtc aatgctgatt ccttctttgt
    43801 gctgacgcaa agaggagcac taaagcgagt ggcgattgct gatattccac agaccagccg
    43861 agctaacaga ggtctgccgg tgttacgaga attaaagacc aagccacaca gagttttctt
    43921 ggcaggaatg gtaaaaggag atactacaac aggtaccatt gacttattta cacatgattc
    43981 agaggacaca gctagtgacc agcaattaga ggttattagt aagactggtc aacaatacca
    44041 gcttgctctc aatagcctgt ctctatcaga taggacaagt aatggctcct ttatttcaga
    44101 gagcatttca gatcaggagg tcgctgctgc aaggctcatc tagccaaagc tttttcgctg
    44161 taccagtgag ggctctgagt ctttcatcga aaaaagatgc aaaacaatga agaaaagaat
    44221 acaaaaagaa aagaggtagg ataatgacaa cagctattga ttgggaaaac ttaggctttg
    44281 aataccgtaa gctgccattt cgctatgtat catattacaa ggacggcaaa tgggacgcag
    44341 gtcgcttaac agaagatgct accctgcaca tctcagaaag tgcaccagct ctgcattatg
    44401 ggcaacaagc ctttgaaggc ttaaaggcct atcgcactaa gaacggctct attcagctat
    44461 ttcgcccaga ccgcaatgca gctcgcttac aggcaacagc tgaccgtttg ctgatgccac
    44521 aggtatctac cgagcaattc attgacgccg ttaagcaagt ggtaaaggca aatgaggatt
    44581 ttgtaccgcc atatggaact ggtgctaccc tttaccttag acccttgtta attggtgttg
    44641 gcgatattat cggtgttaag cctgctaacg aatatatatt tatagttttt gccatgcctg
    44701 ttggcaatta ctttaaaggc gggcttgcgc cgaccaactt tatcgtctct gaggattatg
    44761 atagagcagc tccttatggc actggagctg ccaaggttgg tgggaactat gcaggtagct
    44821 tattgccagg aaaagcagct aagacagcag ggtattcaga tgtgatttac ctagatccag
    44881 caactcacac taagattgaa gaggtcggag ccgctaattt ctttggcatc actgccaata
    44941 atgaatttat tacgccgctt agcccatcaa tcttgccttc aattaccaaa tactccttac
    45001 tccaattagc cgaagaaagg cttggtatga ccgctattga gggtgatgtg ccgattaatg
    45061 atttggaccg atttgttgag gcaggagctt gtgggacagc tgctgtgatc tcaccaattg
    45121 gaggcattca gtatcaggat aagctacatg tcttttacag cgagactgag gttggtccag
    45181 tgacacgtcg attatacgat gagctggtcg gtatccaatt cggtgatatc gaagcaccag
    45241 aaggctggat tgtagctatt gattaaaata agtgaagctt gctattgcaa gctcttttga
    45301 ttttgtgtaa aatagacaag gcgaggtgaa gtgatgagta aaaaagagaa aaaaattgaa
    45361 ctgcaattat gcgatcaaca agtaacagtc aacaatacca agatagacgg ttatcagtta
    45421 caaattggca agcgtgtcgt tggcgagatt gcagagcttg atggcaagtt tgctgtctta
    45481 aaagacagca cagtagatgc tttttttaaa acattagagc aagcagttga aaatattatt
    45541 gaaaactata atttgaacca ctaaaaatgc ttaaaaagac ttgtcagctt acaaaaacta
    45601 tggtagaata gtttttgttg ttacggaaag atagcgaaga ggctaaacgc ggcggactgt
    45661 aaatccgctc ctttgggttc gggggttcga atccctctct ttccatgcct aagctattag
    45721 gttcattgtt ttaatgatga tattggggta tagccaagcg gtaaggcaag ggactttgac
    45781 tccctcatgc gttggttcga atccagctac cccagtcaga ggtatcagat tagcgtctga
    45841 gatcgtcaag gataaaagtt gttgtcattg cgggttacct tgagaaaata tattgttatc
    45901 aaaagctagc ataagctagc ttttgttgga ggatttttta gaatgaatga atttgaagat
    45961 ttgctaaaca gtgttagcga agtcaatcct ggtgatgttg tcactgcgga ggttttgaca
    46021 gttgataacg gtcaagcaaa cgttgttatt gaaggcacag gtgttgaagg cgttttgaca
    46081 cttcgtgaat tgactaacga tcgtgaagct gatattaatg actatgttaa agctggcgac
    46141 accgttgaag tgcttgttct tcgtcaagtt gtaggtaaag atactgatac agttactttc
    46201 ctagtatcta aaaaacgttt ggaagctcgt aaggcatggg acaagcttat tggtcgtgaa
    46261 ggtgaagtcg ttactgttaa ggggactcgt gctgttaaag gtggactttc agttgaattt
    46321 gaagggcttc gcggatttat ccctgcttca atgattgaca ctcgttttgt tcgcaataca
    46381 gaaaagtttg tcggtcaaga atttgacgct aaaatcaaag aagttgatgc agcagaaaac
    46441 cgctttatct tatcacgtcg tgaggttgtt gaagaagcag ctaagcaagc acgtgacaaa
    46501 gtcttttcaa cactttcaga aggttcagtg gtaactggta ctgttgcgcg tttgacaagc
    46561 tttggtgctt ttattgatct tggtggtgtt gacggtcttg ttcacgtaac tgagctctca
    46621 catgagcgta atgtgtcgcc taaatcagtt gtttctgttg gtgaagaggt tgaggtgaag
    46681 gtacttgctc ttgatgagga agcaggtcgc gtatcactat cacttaaagc aacaacacct
    46741 ggaccttggg atggcgttga gcaaaagctt gcacaaggtg atgttatcga aggtaaggtt
    46801 aagcgcttga ctgactttgg tgcttttgtt gaggtattac ctggaattga tggacttgta
    46861 cacatttcac aaatctcaca caagcgtgtt gaaaatccaa aggacgtgct tactgtaggt
    46921 caagaggtaa ctgttaaggt tcttgacgtt aacgctgctg atgagcgtgt atcattgtca
    46981 atcaaggcac ttgaagagcg tccagcacaa gcagagggtg aaaaggaaga aaaacgtcaa
    47041 tcacgtccac gtcatcaaaa acgtgaagct aagcgtgatt atgagcttcc agaaacacaa
    47101 actggatttt caatggctga cctttttggt gatattgaat tataatacta taaaaa
//
LOCUS       DARYUW010000009        42052 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYUW010000009 DARYUW010000000
VERSION     DARYUW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42052
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(550..1902)
                     /locus_tag="TVW11_000446"
     CDS             complement(550..1902)
                     /locus_tag="TVW11_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1364580.1"
                     /translation="MTKTYSIRYRVGITVGEILIGIAILVISLLIIPYLLVFTKQLNI
                     HGTSFDIVLGDKVSTEEITKQMDTLTFDYVLFNRKNGEVLNGNYQKTELSYYETVFED
                     KKPINVGTIDYKAYSNDQILLVVRQPTLPEFVNPSLRKVSFNTLSIILFIVGTLSIVF
                     ISVTKLLREFAHDFRLIQKISLNMGSRDYKIERSTTKISEFNDILAMLYQKDDELTIL
                     LEAERAEKKDLSFQVAALSHDIRTPLTVLKGNLELLEMTDLSNQQISFIGSINHSVSV
                     FEKYFNSMITYSRLLIEERDYQEVIEVTEFMSGLQIEIQEIMHTEQVDFDMKNNLRIT
                     HFKGNRFNLERALINILVNAAQHATDVKQVSLTAKEEQDQLIFEIWNSGSKFSKQALN
                     GANKLFFTEDNGRSSKHYGIGLSFAQGVAVRHQGKLQLLNPLKGAQVNLIIRKYELLL
                     "
     gene            complement(1895..2578)
                     /locus_tag="TVW11_000447"
     CDS             complement(1895..2578)
                     /locus_tag="TVW11_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1364581.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGLNLGGDDYLPKP
                     FSVNQLIAKVSAHLKREERVKHGENVEKITRELLPITFYLQEKMLCVSGKPVPLTSRE
                     YHILELLSSHPNKVFTREDIYEHVYDDEANALFRSISEYVYQIRIKFAPFNLNPIKTV
                     RGVGYKWYD"
     gene            complement(2615..3991)
                     /locus_tag="TVW11_000448"
     CDS             complement(2615..3991)
                     /locus_tag="TVW11_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1364582.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(4159..4290)
                     /locus_tag="TVW11_000449"
     CDS             complement(4159..4290)
                     /locus_tag="TVW11_000449"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364583.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(5399..7345)
                     /gene="thrS"
                     /locus_tag="TVW11_000450"
     CDS             complement(5399..7345)
                     /gene="thrS"
                     /locus_tag="TVW11_000450"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1364584.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(7936..9270)
                     /locus_tag="TVW11_000451"
     CDS             complement(7936..9270)
                     /locus_tag="TVW11_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1364585.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(9272..10270)
                     /locus_tag="TVW11_000452"
     CDS             complement(9272..10270)
                     /locus_tag="TVW11_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1364586.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(10566..12041)
                     /locus_tag="TVW11_000453"
     CDS             complement(10566..12041)
                     /locus_tag="TVW11_000453"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1364587.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(12111..13112)
                     /gene="ccpA"
                     /locus_tag="TVW11_000454"
     CDS             complement(12111..13112)
                     /gene="ccpA"
                     /locus_tag="TVW11_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1364588.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            13286..14371
                     /locus_tag="TVW11_000455"
     CDS             13286..14371
                     /locus_tag="TVW11_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1364589.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSVLPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(14545..16128)
                     /locus_tag="TVW11_000456"
     CDS             complement(14545..16128)
                     /locus_tag="TVW11_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364590.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            16366..17217
                     /locus_tag="TVW11_000457"
     CDS             16366..17217
                     /locus_tag="TVW11_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1364591.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            17478..18146
                     /locus_tag="TVW11_000458"
     CDS             17478..18146
                     /locus_tag="TVW11_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1364592.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            18261..19187
                     /locus_tag="TVW11_000459"
     CDS             18261..19187
                     /locus_tag="TVW11_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1364593.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(19171..19359)
                     /locus_tag="TVW11_000460"
     CDS             complement(19171..19359)
                     /locus_tag="TVW11_000460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364594.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(19471..19938)
                     /gene="smpB"
                     /locus_tag="TVW11_000461"
     CDS             complement(19471..19938)
                     /gene="smpB"
                     /locus_tag="TVW11_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1364595.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(19941..22265)
                     /gene="rnr"
                     /locus_tag="TVW11_000462"
     CDS             complement(19941..22265)
                     /gene="rnr"
                     /locus_tag="TVW11_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1364596.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDAGSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(22352..22588)
                     /gene="secG"
                     /locus_tag="TVW11_000463"
     CDS             complement(22352..22588)
                     /gene="secG"
                     /locus_tag="TVW11_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1364597.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(22634..22780)
                     /gene="rpmG"
                     /locus_tag="TVW11_000464"
     CDS             complement(22634..22780)
                     /gene="rpmG"
                     /locus_tag="TVW11_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1364598.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            23268..25154
                     /locus_tag="TVW11_000465"
     CDS             23268..25154
                     /locus_tag="TVW11_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1364599.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQG
                     ERGEQGPQGERGEQGPRGENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQ
                     PEVKPQPETKPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKR
                     KRKQ"
     gene            25469..26509
                     /locus_tag="TVW11_000466"
                     /pseudo
     CDS             25469..26509
                     /locus_tag="TVW11_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(26672..27265)
                     /locus_tag="TVW11_000467"
     CDS             complement(26672..27265)
                     /locus_tag="TVW11_000467"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1364600.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(27262..28083)
                     /gene="mutM"
                     /locus_tag="TVW11_000468"
     CDS             complement(27262..28083)
                     /gene="mutM"
                     /locus_tag="TVW11_000468"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1364601.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(28498..30297)
                     /locus_tag="TVW11_000469"
     CDS             complement(28498..30297)
                     /locus_tag="TVW11_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1364602.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(30458..35098)
                     /locus_tag="TVW11_000470"
     CDS             complement(30458..35098)
                     /locus_tag="TVW11_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1364603.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(35271..36618)
                     /locus_tag="TVW11_000471"
                     /pseudo
     CDS             complement(35271..36618)
                     /locus_tag="TVW11_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(36683..37999)
                     /locus_tag="TVW11_000472"
     CDS             complement(36683..37999)
                     /locus_tag="TVW11_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1364604.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(37992..38324)
                     /locus_tag="TVW11_000473"
     CDS             complement(37992..38324)
                     /locus_tag="TVW11_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1364605.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(38334..38651)
                     /locus_tag="TVW11_000474"
     CDS             complement(38334..38651)
                     /locus_tag="TVW11_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1364606.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(38675..39574)
                     /locus_tag="TVW11_000475"
     CDS             complement(38675..39574)
                     /locus_tag="TVW11_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1364607.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            39754..40956
                     /locus_tag="TVW11_000476"
     CDS             39754..40956
                     /locus_tag="TVW11_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1364608.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(41119..41595)
                     /locus_tag="TVW11_000477"
     CDS             complement(41119..41595)
                     /locus_tag="TVW11_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1364609.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(41740..41949)
                     /locus_tag="TVW11_000478"
     CDS             complement(41740..41949)
                     /locus_tag="TVW11_000478"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364610.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        12819 a         9877 c         7675 g        11681 t
ORIGIN      
        1 tgaaactcct tttaaaatgt ctctatcttt ataagatttc ctaatatcct gaatttttac
       61 atccatgatt acacctcctt ttttatttaa tcatacggtt tctttttcaa tatttgttca
      121 gaaaataatg aaagcatcaa gatttggaat aaaaagaaaa tcaaacattt ttatagaagc
      181 aagcaaccaa atgttcttac aacgtgaata tggaacctat ctttgtccgg ttaaagactt
      241 atttgggcta caaacgttgc ataaccttca ttatgactaa aagctataat gtcagtaaaa
      301 taatattcag ttgattcttg agtatttaag aatatgaagg ccagcgagtt cagaatatga
      361 aaaaagcccg ttgaacgggc gataatcaag taaacactgt tcagtgattg tctttaggct
      421 cggctgagga gatcaaccta cagaagccaa ggcacttgtt tttgaagcaa tctccaaaaa
      481 gttagacaga aactctaacg aatggaagta cagctcatct aacgggtggt catgatttaa
      541 ctatctactt tacaggagga gctcatactt tctaatgatt aaattaacct gggcaccctt
      601 gagtggattt aataattgta acttaccctg atgccttaca gcgacacctt gagcaaaaga
      661 taaaccaatc ccataatgct tgctgcttct accattatcc tcagtaaaga ataatttatt
      721 agcaccattt aatgcttgtt ttgaaaactt cgaaccacta ttccagattt caaaaattag
      781 ctgatcttgt tcttcttttg cagttaagct aacttgcttc acatcagtag catgctgtgc
      841 agcattaact aaaatattaa tgagagctct ttctaaattg aatcgattac ctttaaaatg
      901 agtgattcta agattgttct tcatgtcaaa atcaacctgt tcagtatgca taatttcctg
      961 aatttcaatc tgcaaaccgc tcataaattc tgttacctct ataacttcct gataatctct
     1021 ctcttctatt aacaagcgag aataggttat cattgaatta aaatatttct cgaatactga
     1081 aacactatga ttaatagaac caataaagct tatctgttga ttagaaagat ctgtcatttc
     1141 aagtaattct aaatttcctt ttaaaaccgt taaaggtgtc cttatatcgt gtgaaagagc
     1201 cgctacttga aaagagagat ccttcttttc agctctttca gcttctaaca atatcgtcag
     1261 ttcatcatcc ttttgataga gcatagctaa tatatcatta aattcactta tttttgttgt
     1321 tgagcgttca attttataat cacgactccc catatttaaa gaaatttttt gaattaaacg
     1381 gaaatcatga gcaaactctc tcaatagctt tgtgacagag ataaatacaa tagatagtgt
     1441 ccctacgata aacaggataa tagataaggt attaaaggaa acttttcgaa gggagggatt
     1501 aacaaactct gggagtgttg gttgtctcac aaccaataat atttggtcat tactataagc
     1561 tttatagtca attgtaccca cattaattgg ctttttatcc tcaaaaactg tctcgtaata
     1621 acttaattcc gttttttgat agttcccatt aagaacttca ccattctttc gattaaaaag
     1681 gacgtaatca aacgtaagtg tatccatctg tttagtgatt tcttctgttg aaaccttatc
     1741 acctaaaacg atatcaaaac ttgtcccatg aatatttaac tgtttagtaa acactaacaa
     1801 atagggaatg ataagaagag atataactaa aattgctatc cctattaaaa tctcgccaac
     1861 tgttattcct actctatacc ttattgagta tgttttagtc ataccactta taccccactc
     1921 cacgaactgt cttaatagga ttcaagttaa aaggagcaaa ttttatacga atctgataaa
     1981 catactctga aatagagcga aatagagcat ttgcttcatc atcatagaca tgctcataga
     2041 tatcttcacg agtgaatacc ttgttaggat gacttgaaag caactctaaa atatgatact
     2101 ctcgactcgt taatggtact ggttttccac taacacaaag cattttttct tgtaaataaa
     2161 aggtgattgg taataattct cttgttatct tttcgacatt ttccccatgc tttactcgct
     2221 cttcacgttt cagatgagca ctcaccttag ctataagctg attcacacta aaaggcttcg
     2281 ggaggtaatc atctccacca aggtttaatc ctttaataat atcgtcttca gtatctttag
     2341 cactaacaaa gataatagga gaagcaactt tatctcggat taattgacaa atttgtgtac
     2401 cttcaacatt aggcatcatg acatctaata aaatcaagtc aaacccttga aaatctctaa
     2461 aattgattgg aaaagtcact tcttgatagg ttgttacctt gtaatttttc atctcaagaa
     2521 tggtccgcat aagttttaaa atctcataat catcatcaac aactagaatc ttatacatag
     2581 tcttacctca taatagttac actgttattt tacactattt tgagataaaa tctgtaatat
     2641 ttaacaatct aattggtttt ccattatcat ccaagctact ccaagagtta ctatacaaaa
     2701 tagttatggc ctcatctggt ttatctttta aatcatattt ttcgatgatt aaacctaagg
     2761 cagcagctac tttaggggct gcaatagagg tcccgtagcc ataagtatat ttcccttcta
     2821 gtgttgggat aataacccaa tcttgctcaa ataatttatt gttaatccaa gtgtcatagc
     2881 catgaagcgc tagcttcttg cttcctccac ctgccgcaaa gatatcaacg acattccttc
     2941 cacgattgga aaagttagat attgcaccat caccatcaac agatcctact gtcacaacat
     3001 tatctagctg tgcgggaata tcctctattg tcccatcgac tgaactaaac gctcttcctg
     3061 tgagagcact gactaagttc ttaagctcag cttgattatt taagttagct ccctcatcac
     3121 caacagaagc aactaccact gagccttgtt tgtgtgcata attgattgcc cgttgatagc
     3181 tattgattag agcagttcta tcttcatcaa tatttgatga agcctttaat aaatactgac
     3241 caagactcaa atttatgaca tcaacatcat cctttgctgc ttgaataatt gcttttaaaa
     3301 tccattcatc ttgagcgttt ccctcttcaa acaccttata cattctaacc ttcatgcctg
     3361 gagcaattcc tgtataataa ccatttgaag acatttgtcc aacaacagat gtaccatgac
     3421 ctgttttatc caaaacatta ttaacatcaa ttgccttagt tactggatcc tccgtaaaat
     3481 tttgaacaga aatgatcttt gaagaaatgt cagtattatt atcagtaata ccagaatcta
     3541 ttacaccaat ggttacctca cctgatgact tatgccaaaa cctactacta gtactaatac
     3601 ttctttgcat atcccattgt ttattccagt aatttaaatc actatctaaa taaaatgcat
     3661 gcccaaactg atatgtcatt ttgggattta ctgtaaaagt attattcctt gaaatgtcat
     3721 caatatagtt acaattcttt tccaaaatca tagatgagtc atttgcagca gcgattgtca
     3781 aaacattaat ttcaggaatt tcatcaagca ctatcattcc ctgatcattt aattgctttt
     3841 ttaccttatt ggtatctaag ctttctttta taagaatatt atattgagtt ttgctactag
     3901 tctcagcata gacatgtaac atatgaaatt gagatacaaa aatagacagt agcaaacaga
     3961 aaatcaacat tttatgcttc atggtcagca ctcctttaag tattgttttt acacttatcg
     4021 tatgactaac atttcagatt tgtttcagat tctagaaaat aatacttact attgtgctta
     4081 tttaagtcca aaaattagca ttacactcat taagtatctg agattaatct agctaacatt
     4141 ctaaattgtt ttctcccact aatcttttgt tcttaattcc gacttataat taaagacaaa
     4201 agctaatttt tctaactgcc tcgcatagca ctcatacttg ccaatcattg ttgtcatcgt
     4261 ctcctgattg agcttagttt cttcttccac ctgctccagt ttactagctg atatgcaagt
     4321 gcaatggtcg ttttttgtga atcacaccta ctttgaatct ggtaaaatca ttctactaac
     4381 aaacttcctg tgtaatttct agtagcctag gtagcctgat aaagagattt cttcaaataa
     4441 aaataaccat gtcgaatgcc agcgctccat ttcttaccag cattttcatt attccccagc
     4501 taaagctcta tccatgaggc taagtgacct gtgcttagaa ttaactcata tccacactag
     4561 tctcagaaat aaagactgaa gctatcatga tgtcactact aggaatgaat gaaatctagg
     4621 gtttctactt gacagtcata gtgagacaaa caagcggcaa tttgctcttc taaactcccg
     4681 atttgtttct aatagcaagc ataaatctcc atagactacc cccatagaaa atggtggtga
     4741 ttggagaaat caccattaag tgcttcacga cgttgaggag ctttcttctt caaactagta
     4801 taaacaatta atggactact tactctagct gtcataggcg tttgagcaat cagtagttga
     4861 aatagcttgc aaccgaaagc acccagcata ctctcaatgc ggatcggaag ttcaatgcca
     4921 cctaactgta gaattttata atgcaaattg tcctttatta agaaccttat tgatcatttt
     4981 aagctttagt tcgggagagg aacgaatctt tttccttagc agctttacaa tcaattaatc
     5041 gtgctaaata ctttaaatgg aattgattga tatcaaattg tttgaatgaa taactctggt
     5101 tttgtaggcc gcagatttct accttgtctt gatgtcttaa tgtcatgtta aaagcacccc
     5161 attcgttaga tagtttgtct aacttttggg gcgcagttca ttcattagat tttttatcta
     5221 atttttgaga agcagtttac ttctgatgag ggcttctata ttgctttcat tagttctatg
     5281 agtgagagca aagctcttgt agctatttgt cccagatttt tttatgtcat ctgttttgca
     5341 agtcaagctg acgtctgctt aatcagccta tctaaaacca gcttgcttgg tctgcttttt
     5401 agccttcagc tgggcgtgat ttgcgggcaa tatcagccaa aatgttatca acaaatgctg
     5461 aaatagcttc ggtatgtgtt gccttactgc catagcggcg cacattaact gacttgtcct
     5521 gcatctcctt atcaccaacg attaattggt aagggatttt actggtttga gaggcacgaa
     5581 tcttatattg cattttctca ttacgatcat ccacatctgc acgaatccca tgatcacgaa
     5641 ggattttagc aacctcccaa gcatagtcaa tatgggcctc attggaaatt gggataactg
     5701 ttacctgacg tggtgccagc catgttggga aagctccctt ataggtttca atcaaaatag
     5761 cagtaaagcg ctccatggtt gaaatcaccc cgcggtggat catcaccgga cggtgttctt
     5821 ctccatcagc accaatatag ctcagattaa aacgctcagg cagtaagaag tccagctgaa
     5881 tggttgatag ggtttcttca tttccaaggg ctgttttgac ctgaatatca agctttggcc
     5941 cgtaaaaggc agcctctcct tctgcttcaa agtaatcagc gcccatttca tcaagcgcag
     6001 ccttcagcat gctttgagca ttttcccaca tctcatcgtt atcgtaatat ttatgtgtat
     6061 cctttggatc acgataggac agacggaagc ggtaatctgt taggttaaaa tcctcataaa
     6121 cgtcaataat cagctgaaga gctcgctgga attcctcctg aatctgctct ggcgtcacaa
     6181 acaggtgccc atcgtttaag gtcatctccc gcacgcgctg aagccctgaa agagcccctg
     6241 atttttcata gcggtgcatc ataccaagct ctgcaatacg aatcggcagc tcgcgatagg
     6301 aatgcacatg gtttttataa acctgaatat ggtgtgggca attcattgga cgaaggacaa
     6361 attcttcacc atctcccata tccattgtcg ggaacatatc ctcctgataa tgctcccagt
     6421 ggcctgatgt tttataaagc tcaactgaag caagcggcgg agtataaaca tgctgatagc
     6481 ctgatgccag ctctttatca gtgatatagc gctcaagcgt gcgacgaatc gtcgctccat
     6541 ttggtagcca aaatggcaag ccttgtccta cctcctgaga gatcataaac aaatcaagct
     6601 ccttgcctag cttacggtga tcgcgctcct tagcctcctc aaggcgtgtc aaataggcct
     6661 tgaggtcctt tttatcaaac caggctgtcc catagacacg ctgcatcatg ttattatcgc
     6721 tattgccacg ccagtaagct ccagctacat ttaacaaatg aaagacccga atccgacctg
     6781 ttgacggcac atgaggacca cgacaaaggt ccacaaattc accctgacgg taaacagtta
     6841 agccagccgc atcatctgca tgctcattaa tcaactcaac cttataaggg tcatccttaa
     6901 aaagctcaag agcctcttct tttgtgatct cctcacgaat acatggaaag ttctctttga
     6961 caattttttt catttcctct tcaatgcgag gcaggtcttc gttagagatt tgaccatcag
     7021 cattatctgt atcataataa aaaccatctg caatggcagg gcctacacca agatgcagct
     7081 tggggaacaa gcgcttagca gcttgagcaa acaagtgagc cgcagaatga cgcagcacct
     7141 caaaagcgtc ctcatgatca gcagttataa tttctatact accgtcctct tcaatggcgc
     7201 gcgtggtatc aattaattga ccattaaact taccagccaa ggccttttta gctagagatt
     7261 tgctgataga gtcagcaatc tcaaaggttg tgacaccaga ttcaaattca cgcaccgcgc
     7321 cgtctgggaa agtgattgta atcatctgtt ttctcctata aaccatctag atacttaaaa
     7381 caagctaatc aagcagggct atatctccca agccttctgc tgctacgaca aaataaaaac
     7441 tgactgcctc ccaaaggacg caatcagcgt ggttccacct ttatttatgc atgacaaaga
     7501 aatcctgtcc tgcacctcag cttggctata tcgtgaccac cgttttatgt ttgcataaaa
     7561 gcaaggaagg agtattacac tagacaccct gtgctcttct caccaaccag cactcgctta
     7621 aaggatgcga cctaatctaa cttgtcttcc tgattattat agcaatattt ggaaataatt
     7681 caagtgattt ttcctaaaaa agctgagata agcccacaga cctccaagcc cacaaggcaa
     7741 gaatgactag gcaaggaacc ctgaaacttc tgccacaagc ctttgaagaa cagctcaaac
     7801 aggacttgcc gcctgtcgtc tcagttcaca agacaacaaa ctaaatcctt tagacaaatg
     7861 attatcctaa agagctatct gctctctcac gcagaaccaa agcctgtaat tgcaggcttc
     7921 tttgtttatt tagccttagt ccaaaaagtc tcggatcgca ttgaccagct tgataggggc
     7981 tttgagcacc ttgacagatg tcagtgcagt tgccttagct gctcgcttag gcaagtgaat
     8041 cgctccttga accagcttga ttgagccact cttttctgtt cgattgagat agagacttag
     8101 ctttttcgtc tctttattgt gtcgcgaaat caaggtatct aaataaaagg tgtacactga
     8161 tttgccaaaa tgctgagctg aaatctcata gcgcttctca tctagcagcc tctggttcat
     8221 ttgaggtgtt tctaaaatgg catcaataat cgcatctgac aattctgact cagcataata
     8281 aagtgttcca aacatcttat cggtaatcaa atcatctagg tagggattgc catgagcgat
     8341 gatgggcttg ccactagcaa ggctctcaat ataagttagc ccctgtgtct cactcgttga
     8401 cgctgaaata aagaaatcac aggccttata ataaagccca acctgatcat gagcaatcat
     8461 accagtaaag accacatgat cctcaacgcc taagctgaca gccagctcct ttaaggcttg
     8521 aagataagga ccatcaccaa caatgacaag cttgatcctg ctattttcac tcaaaacagc
     8581 tggcagctga tggataatag cctgaatatt cttctcataa gacacccgcg acaggctcaa
     8641 tagcatggtc tcatcatcag aaatggccaa ttcctttctc aaggcagcga catcttcttt
     8701 tttaatatcc tcacgaacat agttctctag tgcaatgcca gtcggaatca cacgcttagg
     8761 aatggttacc tcgtaccctt ccaaaagatt tagcacaatc cgacttgggc aaataacacc
     8821 atcaaggtcc tttaaatacc cacgaagcag gggcttgacc atgctaggtc gaatgatctt
     8881 accattagca atatagctca cataatcctc atactgggta tgataggtgt gaacaaccgg
     8941 aattcttaag gccttgccca ccattttgcc caacaaacct aagctaaact ctgtttgagt
     9001 atggataatg tctaaatgat attccttagc aatcttgtag gaggaaatga gcccacgata
     9061 aaccacacga cgatccgtaa aggacacaaa aggaacactt ggtaaccgaa taatggtcgg
     9121 atcctcaaag cgcttaacat gcttgtctgt tgttgtgaaa atatagacct catgcccctc
     9181 tttttccagc tcctccttta gggtgcgaat actggtagcc actccggaaa cctgtggaaa
     9241 ataggtatct gtaaatagac ctacacgcat cttataactc cattactttt tgataaatag
     9301 ccactaattg atgagcaatc ctatcaaggc tgcgcccctc ggcgacacga tagccggcct
     9361 ctgttttgtt gctttcccct gaaagaatgc gtcttaaggc tgcaacaaag cctgaggtat
     9421 catttgccaa ctcagcactg tcttgatcaa tccagccctc atagactggt atatcgcgta
     9481 aaacaagatg ctgccggctg gctaaggctt cgagaaccac aatgccttct gtttcctcac
     9541 gacttgggaa gaaaaaggcg tcagccccag tcatagcccc ctcatacaca tctcccttga
     9601 tataaccagg gaagatcaca ttatcggggt gcttaccgtt gacaatctgg cggacacgag
     9661 caggaataac ccatttattg gtatcaccaa accagataaa ccgaacatct ggcatcatct
     9721 cagcaacctt aacaaactca tcaatccctt ttctaagaaa gaaaagcccc gctcccatga
     9781 ctaccttctc accctctttg aggttaaaat aacgccgaaa ggcagcttct ttgtcagcat
     9841 tagcaccata ttgctccaaa tcaatcccat tagatactgc aaaaatagga gtcttaaccc
     9901 cgtaatgctc aatcaaggct ttagaataag gggtcggtgt gataatggcg tccgccttat
     9961 tgtaaaagcg gcagagatag gctttgaata aaggagacac tagatttgaa aaaataaagg
    10021 aatttctaaa atcctcctct gtcgaatgcc catgcatgat caccttttta ccggcctttt
    10081 gagcctttga catcaaaagc cagcttttaa gcccataggt attgagatga accaaatcat
    10141 agtcgtcctt tggatcagtg gtgaactcct gtcccacaag cgatagcgct tttgcctgat
    10201 gcttaatcgc tcgcccgata cctgattttc ttaaataatt ttctgcttct aaatacaata
    10261 agactttcat actgtctatt atagcctatt ttatggtatt tttcactaag agagttaaaa
    10321 atcagccctt agactgattt tagggtaagg cttcttctac ccctatactc atctcaaaaa
    10381 tgcttttaag tcctgctttt gctgtcatca aatggctgat cttggtaata tcagctagac
    10441 caagatcgtg aaagctccag ctcaaggctc acgtattagc cctttcaaga aagcctccca
    10501 cctttctcac tggccaaaaa gccagcaaga cctggccttt tcttctgatt aattcagcct
    10561 atcagctaag cttcttcttt tggctgtgct ttttgtaaca cccaggctga gatagagcct
    10621 gcctctacct tgaaatctgc ccagccatcc tcagcaacaa caacagtctc ctgacaattg
    10681 tctaagaaat cacaaaaaac ttgaccagca taggcttgac caacctccat gtgcttccag
    10741 cctgcatcgc cattagacaa aacaactgcc aaaggctgag gacgctgatc atctcctaag
    10801 caggtccagc cgatacaatt ggcatgatca aagtaatcaa tctgctcccc atagaccagc
    10861 tgctgcctga gctctgccat ttttgtgata acctccttaa aactttgctg agggtagtct
    10921 ccagaaatac cataataatc accataaaaa agacagggct tgccctcttg tcgtaaaaga
    10981 atcaggccat aggctaaggg cttgaaccat tcctcaacag ttgactctaa ggcttgccct
    11041 ctttgggtgt catggttttc cacaaaggta atagcaaggt ctggccgact agccacaaga
    11101 ctgccatcaa aaatagtggt caaatcaaaa tcagctccct gctggctagc attaaaaaag
    11161 gacatgtgca gcgcaacatc aactagagca aactgagcct tcgttgcttc gaggtaatcc
    11221 tccatagatt cctgatcaga cttccagtat tctccaaaaa cctctaaatc gggctttagc
    11281 tgggtacgaa tatcattgat aaaggtctga ataaaataag aatcaatatg cttcacagcg
    11341 tctaaacgaa agccctcaat accagttgtc tcaataaacc acttggccca atcctgtaaa
    11401 ttttggatta cctcaggatg cttgaaatct aagtcattgt acattagata atcaaaatta
    11461 ccatgctcat cgtcaatcag ctcatcattg gcccagccct tgttatcacc ggtgatcatg
    11521 taaatacctg tttcattagc cttggcgtca taatccaatc ccgtaaaatg gtaccagtgc
    11581 catttaaagt cattataggt attttgtctg ccgggaaaat caaagcctgt ccagccttca
    11641 atctcatagg gctctgtaag ggcctgctga cggttctctg gattcatttt gatcacagaa
    11701 aagcgttcct tgtgatcacc attagccttg tggttcagca caacatcagc aataggcttt
    11761 atttttgcct cttttagggc tgcaatcagc tgcaaataat cctctttgct gccatatttt
    11821 gtgctgacag ttccattttg gttaaactct cccaaatcaa acaaatcgta aacaccgtac
    11881 cccacatcat cagagctagt gcccttaaag gcaggcggca gccacagctg actaacccct
    11941 agctgttgta gctcaggaat actgcttttc agcctttgcc aatgccttcc atcggcaggc
    12001 aaataccatt caaaggcctg cattaatagt tgatgactca tcttaacctc ctaaaaagga
    12061 caaaccagaa aactcctagt ttgtcctcaa aactgcctaa acaggcagaa ctattttgtt
    12121 gtcccacgct ttttaatgcc atggttcaat aaaatttctt tttcttctaa ttcttcctta
    12181 ttcatgatct tagtgagcat acgcatgcta acagccccca agtcatagac cggctggctg
    12241 atagagctca aatttggacg tgtgtactga acgactggag aatcattgct tgtgataatc
    12301 tcaaagtctt ctggaacacg cttaccagct tcaaaaagac cattcaaaag gcctgctgcc
    12361 agctcgtcct ctgcaacata ggcagctgtc gctccggaat tgatcacacg ctgagccagc
    12421 tcaaagcctt ccttataaga atagttggcc tcaaacacca gaccctcttt aaagtcaagc
    12481 ttgttcttct tgagtccgtc cttgtagcca gctaaacgca cctttccgtt gatatcatca
    12541 atgagcggcc ctgaaacaaa ggcaatgctt tggtggtctt tagctaaaat atccaccaca
    12601 tcagcaacag ccgccttata atcaatgtta acacttggca gctgatgatc cagatcaacc
    12661 gttcctgcca gaacgattgg cgtacgcgaa cgagaaaact ctgcccgaat cttgtcagtc
    12721 aagtgatgtc ccatgaaaat aatgccatcg acctgctttg caaagagggt attcacaaca
    12781 ttgacctctt tatcatcgtc ctcatcactt gaagcaagaa caatattgta cttgtacata
    12841 gcagcaatat catcaattcc ctttgccaga atagaaaaat agctatttgc aatattagga
    12901 atcacaacac cgactgttgt tgtcttttta cttgcaagac cacgagcaac agcatttgga
    12961 cgataatcga gacgatcaat aacctctaag acctttttgc gggtattttc ctttacattt
    13021 ttgttaccat ttacaactcg actaactgtc gccattgaaa ctcccgcttc gcgagcaaca
    13081 tcataaatcg tgattgtatc atctgtattc attcttcatc ttcctttcta actgaaaatg
    13141 acgctttcaa aaagtatttt agcatgattt gtaaccactt tcaagtatta acggttgatt
    13201 tttgaaaaag ttttcaaaaa ttcataataa gcttgctttt ttaagtattt tttggaaaaa
    13261 tagaaggcag aaagaaggtt tatctatgac taaattagat caaattcgtt tgtaccttaa
    13321 tcaggaaaag gctgagcttg ctatcttttc tgattctgta acgatcaatt acttaactgg
    13381 ttttttatgt gatcctcatg aaaggcagat gttcctattt gtctatcatg acaaggctcc
    13441 tgttttgttt gtaccagctt tagaggttgc aagggctgaa caattgctgg acttccctgt
    13501 ttttggctac gttgactctg aaaatccttg ggaaaaaatc aagtctgtcc taccaagcac
    13561 agcagcaaag accatttacg ctgagtttga tcatttgaac attaccaagt ttcaagggct
    13621 gcagagtgtc ttttcaggac gctttgacaa tctaacccct tacattcaaa gaatgcggct
    13681 catcaagtct gctgacgaaa ttcaaaaaat gctgattgct ggagaatttg ccgataaggc
    13741 tgtcaatgtg ggctttgata atatttcact tgacgtcacc gagacagata tcatcgctca
    13801 aatcgaattt gaaatgaaaa aacaaggcat cagcaagatg agctttgaaa cgatggtttt
    13861 aactggtaac aacgctgcaa acccacatgg cattccagga accaataaaa tcgaaaacaa
    13921 tgccctgctg ctctttgacc ttggtgttga aacattaggc tatactagcg acatgacgcg
    13981 tacagttgcc gttggaaagc cagaccaatt taagcttgat atttatcagc tttgcttaga
    14041 ggctcagcta actgctcttg atatgattaa gccaggagtg actgcagctc aggtagatgc
    14101 cgctgctcgc caagtgattg aaaaggctgg ctatggcgac tacttcaatc acaggctcgg
    14161 ccatggtatc ggtatggacg ttcacgaatt tccatcaatc atggctggca atgacctgat
    14221 tcttgaagaa ggcatgtgct tctcagttga gcctggtatc tatatcccag gcaaggttgg
    14281 ggttcgtatt gaggactgtg gtcacgtaac taaagacggc tttgagctct tcacccaaac
    14341 accaaaagaa ttactatact ttgaagggta ataggaggct taaaaagcct gaaacaaaat
    14401 gtctcagacc ctaatatcta aagcaacagc acttggtctg ttacttttca tattacaggc
    14461 tattttctca caaggaaaag tcaaagcacc ccttgatggg aaatcagagg ggcaaaagct
    14521 atttgtacta agctcaaaag ctaatcaaga gcacctgacc agctctttat cctttaagtg
    14581 ataaatgcaa tcataagact gtgcattata tttatgagct atctcaacca tggtgcaggg
    14641 gagtgaatgg agtaactcac gaatctctct ggcgctttct ttgtctaggg cagctgtgac
    14701 ctcatcagcc agcaaaatcg gttttagtat cagcaagcag cgtgcaattt ccagcttcat
    14761 gatttgcccg ccagagagat tttgcccatc tagatggaga tcaagatctc cgtttagctc
    14821 attccaaaga tgaacctgct gtaatatctc ctttagtcgc tggtccgaat aatcctgaaa
    14881 cagcgtgaga ttatctcgca agcttccttc aaatatgtaa ggcttttgat gtatcaaaga
    14941 cacaacatca taggaaggaa aatagcgttt tccattggca gcttcaaaat aaatagttcc
    15001 agaataatcc ttatcctcac cacacaaaag agcaaataaa gtagatttcc cactaccact
    15061 ggctcctgtt agcaaggttt tgtgccctgc tgaaatatga ccatctatcc cttgaaaaat
    15121 aagcctatga tcaaaatact tatctaacct cttaaagtag atatcaagtg taagatcatc
    15181 tgtaggggtt aaggcttgat gttttgtctc ttcctccaga gccaatactc taaccatctt
    15241 ctccttaaca gcagttgcag actgtaaact cgaagtagct tctaataatt gctgcaaggg
    15301 agagacaaga ttcgtagaag ctgttatcat agcaatgaga gttgttagtg atagacttga
    15361 atagctcatc accaacagac caataataag aggactaacc aagccaatcc cttttaatgg
    15421 accagtccaa aacattacca gattgtgggt agtataatag ctatattgct tgtcttccat
    15481 atgctgaatc atttctaaca catggtgagc aaaagcttcg ttggcttgat tactctgtat
    15541 cgtgtctgcc cccttagtaa aatcggtgat actggctagg cttttctccc tcgcctgact
    15601 aagctctaag cctcgtgatt gaagtaagtg attgaacaca aactgtggaa taatcatcaa
    15661 aaagccacca atagtaaagg caataccaat ataaatatcc tgcaaaagaa ggtacaagac
    15721 agaggctaag atagataggc caaaaacagg ataaatgaat aaggggacca aatactcctg
    15781 ccaaaacata ggaatatctt gggtcaaaaa cgaatttaag gctgaagtaa aatagttgag
    15841 ctgtttatga taaaaatgat ataaagcctt ctttgcaata aggcaattaa acgctctaac
    15901 catagaacgt gctaaaatgt tattaagata catgcacata taaataaaga caaaaaaagc
    15961 tacgcctcca agaccaaaaa gcaataccat tcctttattg ttcatatcaa tttgccctgc
    16021 tatctgaatt aatactgata acaatagtcc ctgcaaggaa tagagcaaag ccaataaact
    16081 atacaagcaa agctgccatt ttgaaatgac ttgtaaaata cttttcatat caatcactcc
    16141 tcacctgaaa cctaaatgta tcgctctctt ggaaagtata aacgaaacat cctcatacac
    16201 caatcatttc caccacaaac tagattcttg aatgttaaat caagctcttg atcaaaatca
    16261 tgttctctga tttcttgaac aaccattggt tctctccttt cattcttact atttctagta
    16321 tataatggga aaaaatacga aaggaaaaat ttcggaaatc cggatatgaa tatcagagag
    16381 aaatttaaag caattcgtaa acaaagaaga ctatccttaa aaacgcttgg taaaatagct
    16441 ggctcagcca ctagtatttc tgacttcgaa aatggaaaaa cgaacctttc taatgatgtt
    16501 ttattgcagc ttttaggctt tatgattgtt gaaataaacg agctattcga atgggaggat
    16561 tttcacgaaa aggaattggt tgaagccatc aagcaaatcg aactggcaat aaaatctaaa
    16621 catattcctg ctctatctca gctacagcag gactttcaaa gcttatctaa gacaaaggaa
    16681 cagtacattt accacatcat ctcactgatc ctaaccatca ccattgcaga atatcaaaac
    16741 aaagagatcg atccacacat catgtctgag ctaacagact acttcttttt cttggagtat
    16801 tggactaacc ttgatgtcgg cctactagga aacatcgtcc actacatgac aacagatgcc
    16861 ctaatcttat tgacaaatga catcttagag catacgcctc aagtactccg aaataaccta
    16921 gatcgtatta ggatcgatac tgtattaaac tgtcttactg tcttgattaa tcgtaaagag
    16981 gagaaggcaa gcagaacact tcttaaatta ttatttaaca aacattatcc taattacttt
    17041 gcctttgaaa agctctattt acatgaatta caagcagtct atgattttaa ctggaaagat
    17101 aaagaacagg cgcttgcagc tcatcacgtc atactggcta ccatttcatt actatttaca
    17161 gctgatgaag ccaaagaatg ggacagcttc tttcaagaaa gtactagctc tttgtaatac
    17221 tccagctcat acactaaaga aaagcaagga taatcacata aaaactaatc acatcacttt
    17281 gccctgctag ctgaattagc ttgggtcatc tcttatgccc agcaaaacat catctagtct
    17341 cagctttctt ccaaagcttc ttgtctctct gggcttgcaa gcttttgata gcttaagagg
    17401 cacaagcatt aacaaaggct aacaaatgcc tgtaaaaata tgctatgata ggggtaacaa
    17461 aaacctagga ggtgcttatg tcacacaaat ccattcatca acagcttaga aatgcttttt
    17521 cctttcggac agcggtacgc gtctacaatg accaaaaaat agccaaagaa gacttagacc
    17581 tgattttaga tgctgcctgg ctcagtcctt cctctatcgg ccttgaggcc tggcggtttg
    17641 tcgttttaga aaacgaagct gtcaagcatg agctaaagga ggtctcttgg ggagcagttt
    17701 atcagtttga gacagctagt catatgatcc ttttaatcag cgaaaaaaac gccagatatg
    17761 atggcgcttc tatcaagcaa agcttattgc gcagaggcat tactgacgag caagccttgg
    17821 ccagtcgtct ggcatgctac gaagccttcc aaaagcatga tatgaaaata gcagatgatc
    17881 ctcgggctct ctttgactgg actgccaagc aaacctatat cgcgcttgct aatatgatga
    17941 ccactgctgc ttttatgggg attgactctt gtccgattga gggctttaac tatgacaagg
    18001 taaatgctat cttagcaaaa catgggatta tcaaccctga taccgagggt atctctagca
    18061 tgctgtcttt aggctatcgc ctgcgcgatc ccaaacactc acaaaccaga aagcccagag
    18121 aagaggttat ttccttcttt aactaagccc cttttgccat tgctcccaaa gaaagtgcaa
    18181 agacagtcct ttgccttttc tttttcataa ctgtcgaatt atggtacaat gtgtcaaaag
    18241 acctatggaa agtgatgcct atgacattat tatctgtaat tatcccctgc ttcaacgaag
    18301 aagacacgat tattccttat cttgaagaaa tgaagcaaat cgaagcggcc atgaccagcc
    18361 aattagcctt tgaatatctt tttattgatg atggctctac agatcaaacc ctgagcgtgc
    18421 taagagagct tgcggggcgc ttctctaatg tgcattacct ctccttttca cgacattttg
    18481 gcaaggaagc tggactatta gccggcctag aagaggcaaa aggaagctat attacggtga
    18541 tggacgttga cctccaggac ccacccgagc ttctcccgct gatgtatagc aaattacagg
    18601 agggctttga tgtggttgcc acaagaagac agagccgaca aggagagcct gctatccgtt
    18661 ccttttttgc tagactcttc tacagattag tcaagcatgt ctccaacacc gaaatcgtcg
    18721 atggggtacg tgattatcgt ttaatgacaa gacaggtggt ggatagtatt ttagagttgg
    18781 gagaggtcaa tcgcttttcc aaggggattt tttcttgggt tggctacaat actgcctata
    18841 tcagctttga caatcgtaag cggcagtacg gcaaaaccag ctggaacttt cttgagcttt
    18901 tgaactactc gatagacggc tttatcaatt tttctgagat gcccttaacc attgctacct
    18961 ggactgggac acttagcttt ttgctatctc tgctagccat ttgctttatt gttatacgca
    19021 agctgctttt tggtgatccg gtttcaggct gggcaagcac tgtatccatt atgctattta
    19081 tcggtggaat tcagctgttt tgcatgggaa tcattggaaa atacatttcc aagatcttcc
    19141 ttgaaaccaa gaaaagaccc gtctacatca tcaaagaaaa gaaataacag agcaatcatc
    19201 aaggccccta tcagccgcca atgaggccga taaggactgg ttgccctcat catgacaagc
    19261 acgacaaaaa gacttgatgg tcccaatcaa aaccatcaag tcttttttag tatgtgacct
    19321 tgcgtctgcc tcgcacctaa aaagacgaga taatgtcata accaccgtct atctactgac
    19381 cccaaaaagt tggacaattt agttttaagc aagggattta gttctgtatt gcacaggact
    19441 aagcaaggcc atcagcttgt aaacagacgc ttagcggcgg ttcacactct tcatcacacg
    19501 ccgaatgtca cgatcctgct cgcgtcgctt gatcgattca cgcttgtcat aatcatgctt
    19561 tcctttggca aggccgatta acaccttggc aaagccatcc ttaagataaa cctttagagg
    19621 aataagggtc attcctgtgc cctttagctc atctgctagg tgctgaatct cacgcttttt
    19681 gagcaataat ttgcgcgtgc gctccggatc agcattccag atatttccct gctcaaaggg
    19741 agcaatatga acattgacca accaggcctc accattcttg atttgggcaa agccgtcctt
    19801 gagctggata cgcgcggcac gaacactctt aatctccgta ccggtcaaca caattccagc
    19861 ctcaactgtc tcaacgatat gatagtcatg acgagccttt ttgtgttgcg ctaatacatt
    19921 accttcacct tttgccatgc ttaactcctt ttacgacctt tctttttagc agctttttgg
    19981 taaaatggtt tctttgcttt ttttcttgtc ttctgctttg attttggctt tgagggcttg
    20041 gactccttac tcctgctagc ccttgaagca gccttttgcc tgtgcttatg cttagcttta
    20101 gctgaccttg tggtcttttc aaccacatca tagtcactag ccaagtaatc aaaatcaatg
    20161 tcacctgttt ccttgtcagc cctcaccaat ctaacccgaa tcggctgacc tgctctaaat
    20221 acctttcctg agcgttcacc ctttaaggag agtgtccgtt cattatagtg ataatattca
    20281 ggcaaattgg taatatgcac cagaccttca attgtatttg gcaattcgac aaacatgcca
    20341 aacttaacca cactagcaat cacgccatca aacacatcac caatataatc tgccatgtat
    20401 tctgcttttt tcatcgcctc aaccacacgc tccgcgtcaa ttgcacgacg ctctagctga
    20461 gatgacgata ctgccaattc tggaataacc tgtgcaaaat gatccacctt ctcctgcgtg
    20521 atctgattgt attctcgaat catgcggtgc accagtaaat cagggtaacg acgaatcggg
    20581 ctggtaaaat gcgtgtagta gtctgctgct aagccatagt gaccatgatt atgctcagaa
    20641 tacctagcct gctgcataga gcgcagcagc atcatattca aaacctctgc tccaggactt
    20701 ccttctacct ttgccataaa ggcctgcaag gcttcttgag aaatcttatt agcagttccc
    20761 tgaatctgaa tcccaaaggc actagcgtaa tcaataaagg tctgcaattt ctctgccttt
    20821 ggctcctcat gaacccggta aataaatggc aagccagccc ttgaaaaatg ctcagcaaca
    20881 cattcatttg ccgctagcat aaaggactca atcatgcgct ctgcaacacc tcgctggcgc
    20941 aagaccacat caaccggcat gcccttatca ttgacaataa tcctagcctc ctgcgtgtca
    21001 aagttcaagg ccccgcgctt cacacgcatc gcctctaaga tctgatgcag ctcaaccata
    21061 gtactcacat catcagcaat tctatcaaat tccctaagcg cctcactgtc acctgcaatc
    21121 atctgattga ccgcgctgta ggtcattcta aaggttgtgt taatcactga ctgacacagc
    21181 tgataatcaa ccacatgtcc ctgatgatca atctccatga tcgctgactg ggtcaaccgg
    21241 tcaacctttg gattgagaga gcagatacca tttgacaacc gctccggcag cattggcacc
    21301 acacgatctg tcacgtaaac agaggtcccg cgcgcagctg cctcacgatc caaggctgac
    21361 ccttccgtca catagtagga cacatctgcg atatgaaccc caagctcaac gtttccattg
    21421 gccaatctct tgatatggat ggcgtcatct aggtctttag catcagcacc atcaatagtg
    21481 atggtcgttt ctttgcgcaa atcaacacgc cccataagat cctgatcact cggagcatct
    21541 ggaatggcat tggcctcagc tagaacgtca tctggaaacg ccgatacaat atccatagat
    21601 tccaaaacct ccagcacatc aatgccgaca tcatgctgat gcccaataat atcacacaca
    21661 gtccctacaa aataatcctg cccagcctta gggtattgca caatatcagc cttaatgatt
    21721 tcagtaccat ctaaggcaat tggagatttt gcgatataaa tcctctgttg aatcctttga
    21781 tttttcgact tgatgtagcc agcatactta gggtgatcat catctaaaat aaccctacca
    21841 acaaccgtct ttaaagagcg ctccacgata gctaccacgc gagcctctgc tgctgtagcc
    21901 ttaagccgat tagctggttt tttaataaca gcctcaaccc tatcgccatc actagcatac
    21961 cccacatcat cacgaccaat aaaaatgtcg tcctcattgt catcaaccga caaaaagcca
    22021 aagccagcct tattggcacg aaaaatacct tgaaccctta tctctggctt tttttgctgt
    22081 ggtgctctaa gaaacacctc accctcatct gaaaaagaca aaagtccctt gccttccatt
    22141 ttggaaatgg ctttaatcag gcgaggaaag ctccccgcat cagtcatctc tagtgcagcc
    22201 gccaaatcat gaatatttga ttggccatgc tcctttaaat aattcgtaat gttctctatc
    22261 atcataccta tcttctattt ctaacaccat acttgatggt tgtgctcatt gataaaaaaa
    22321 tgagctagac taactctgtc aagctcactc cttatttact tgataaaatg gcaagcacta
    22381 acgcaattcc taaccaaaaa aacactagaa ctgctgtaaa acgttgcata aaagcttcaa
    22441 atccgcgagc ttttgtacgc tcaaacaagg cttctgagcc actgctatca aaaacattgc
    22501 tactaggatt tttttgtggc tgcataaaga tagcaatcac aagcaacact gataatacta
    22561 gcaatatcgt aagtagtaag tcgtacatgt taattcctcc actgtagtct caatcattct
    22621 aacacaaaac caactaagat tcaacatgca gcgttacttt tctctcctta ggacagtatt
    22681 taggaacctt aatcttctca gggtgacttg ttttattttt actagtcaaa taatttttgc
    22741 tgccgcaatg gctgcactcc aaatgaatct ttactctcac atcatttccc taatcttact
    22801 atattttatc agcgtcataa ggcttcaaat cacccgcagc ttctttatta aagatatctc
    22861 tagttattat agcatattat ccagtaagaa aacaaactca ggacttttag caaaaaaggc
    22921 ttaagcgcca accaataaac attccaaggc tatcggggaa tattttctaa tggttattat
    22981 aaatcatgaa caattaccta acaaagcaac tccaaaacaa agataaaaga cgaacattca
    23041 ccttgctgct cagctatcaa gataaacaat cctgatagca tcaattttct ttaggtcctc
    23101 agcaatcggt tgtaatatca gacaattcag gtgttgatta aaaaaaacga aactacggag
    23161 accaattgtc agaaagctat tcacagcccg caggcgtcgt gctaaagtat tgtctggaaa
    23221 aagaaaggtt taggaatgat tatacctaaa ctcaaaggag agaaacaatg agaaaaacaa
    23281 tgaagaagat gctagcagcc tcgacgctct gcatcatcat gtcaggcagc ttcatcagcg
    23341 gctcagctag agtgttggcg gagaagtatt atggttttaa tgatggcaca ggagagcatt
    23401 caccattccc tgtatacgtt actccaatta ctaaacctaa taggaatact gccaaagttg
    23461 tctactgttt caataaagat atgaagtggc cagaaacttg ggataaagca gcaccaaaaa
    23521 aaccagataa tttacctcta tactacgata tggaaggtac tgatcaatta ttcagtacat
    23581 atgcaagtgg acaacttact cctaatgtca gtaaagtctt agctaatata atggctaaag
    23641 gttatccaaa caacaatgag tttgctcacc attttaaact cactcccaat tccgctgtaa
    23701 aagttactca aatcgcagtt tggactgtta cggataacct aaaaaactat tctcaataca
    23761 gtctaaccag agaagaggaa gctgcattaa attacctaac tgacaaaaat ggggacgact
    23821 ttagcgatag tatcaagtta aaattataca ttccacaaaa tcctcgaact ataaaatatc
    23881 aaaatcttct aggttatgac ctaatagtta aaactccaga aaaaaaagat aattgtaaat
    23941 gcaccaaaat ttatatagaa gataatggaa aagatggcta ttatctgtat atttattatg
    24001 acaacaatga aaataataga tatgactcgg acaaagatag cctattgcaa aagaaataca
    24061 taaaaaatgg gaaagatggg aaaccaggaa gaccaggggt tccaggactt cctggccctg
    24121 ctggacctca agggcctaga ggagacaaag gagaaaccgg ggaacgtgga cctaaaggtg
    24181 aaaaaggtct agacggtaag cctggtgaaa agggtcctaa aggcgataca ggaaaagatg
    24241 gtaaggacgg acaacccgga cctcagggac ctaagggtga ccctggacgt gatggaaaag
    24301 atggcgaacc tggaaaacct ggcgagcgcg gtgagaaagg acctcaaggc gaacgtggac
    24361 ctcaaggact tcctgggccc aaaggtgagc ctggaattcc agggcctaag gatgaagatg
    24421 gaaaagatgg tgctcctgga catgacggac aaccggggcc taaaggtgaa aaaggggacc
    24481 ctgggcaaca aggcattcca ggacctaaag gggaacctgg acgtgatggt aaagatggag
    24541 aaaaaggcga gcgtggagag caaggacctc aaggcgaacg tggagagcaa ggacctcaag
    24601 gcgaacgcgg agagcaagga cctcaaggcg aacgtggaga gcaaggacct caaggcgaac
    24661 gtggagagca aggacctcaa ggcgaacgcg gggagcaagg acctcaaggc gaacgtgggg
    24721 agcaaggacc tcaaggcgaa cgcggagagc aaggacctca aggcgaacgc ggagagcaag
    24781 gacctcaagg cgaacgtgga gagcaaggac ctcaaggcga acgtggggag caaggacctc
    24841 gtggagaaaa tcctactcct accccagatc caatgccaca accagaacca caaccagaac
    24901 cacaaccaat gcctgatcca gcacctaaac cagaatccaa gccagaacct aagccgatac
    24961 ctcaaccaga ggttaagcct cagccagaga caaaacctca acaaccaaac aagccatcaa
    25021 ccattactag ccaatctagc ggcaaatcac tgccaaaaac aaatgacact ggcagcttga
    25081 tcacagcatt tggtacaggc ttactcactc ttcttggact aggcttccta gcaaaacgca
    25141 aaagaaagca ataattaaaa cactacccat agccttttaa tcattggcta tcaactagat
    25201 aacaaaaagc ttatcgtttt actcctaacg ataggctttt tcgcattccc tattgcttgg
    25261 tctcaatact atttttccag ctttaggctg gttttgctaa tccaaaataa tatcagacaa
    25321 tttccgtttt aattaaaaaa aaaaaaaaaa cgaaactacg gacgccaatt gtcagaaaat
    25381 ggttcacagc ttagagtcac catgttaagc tattctacga agaagaaagg tttaggaatg
    25441 actatttcta aactcaaagg agagaaacat gagaaaaaca atgaagaaga tgctggcagc
    25501 ctcgacagtc tgcatcatca tgtcaggtag ctttatcggc ggatcagcca gaatcctagc
    25561 cgagcagtat tatgggtgga atgatggaac aagagtaaaa tcaccttttt tcctttatgt
    25621 tacgccaaca aatgaaacga ctaggaaaac cggaaaaaat ggtacaatag tctattgttt
    25681 caacagagat aaggaatggc cagcaaattg ggaagaagga agatccttag aactagtgaa
    25741 tgctgaaaca gcttataaat tacccatcta taataaatta ctaggtacaa ctgattcctt
    25801 tactaaaaat gctagtaaac caagagtatc tggagatatt ggtaaagcgc taatagctgt
    25861 actgaaaaat ggttatccta ataaaaattt atccggatta gatgacacta aaagtcgaat
    25921 actaactcaa ctagctatct ggtatttcag tgatagttat aataaagatt attttaaaca
    25981 aaattatgaa ttaactgatc aagaaaataa ctctcttatg gagctgatta aagtcggtga
    26041 ggaagcagct caaaaacaag aaaaaccaga atatcattta gatatatata taactacaga
    26101 aaaaaattat taacataaac cttatcaaaa cctgcttggt tctactctaa ttcctaaact
    26161 tgaccctaag cctgaaccag aaccagatcc taagcctaag ccagatcctg aaccaatgcc
    26221 taaaccagag cctaagcctg aaccagagcc taaacctgaa cctaagcctg aaccaatgcc
    26281 tgatccggca cctaaaccag agcctaagcc tgaaccaatg cctaaaccag agcctaagcc
    26341 agagacaaaa cctcaaaaac caaccaagcc gtcaaacgct actagccaat ctagtggcaa
    26401 agcactacca aaaacaaatg acactggcag cttgatgact gcacttggta caggcttact
    26461 ctctcttctt ggactaggct tcctggcaaa acgcaaaaga aagcaataag ctgaataagc
    26521 taatgcaaga cagcactagt atataatgcg tgcatggtcc atctaatgca gcacaaaagc
    26581 cttatcgcac cacgaatggg tacgataagg ctttttgcat acgctataga agctccaaaa
    26641 ccactagact agggcaacag catggcaagg cttacgcctc taaatcatgc agagccttac
    26701 taatctgtgt ctctaaagcc tgaaaatcac cagtattatc aatcactaaa tcagcataag
    26761 ctcttttctg agacatcggc agctggctag caatccgctg cctagcagct agctctgtca
    26821 attgattacg cttcatcagg cgcttgagct gagtctcctc atcaacatag agcagccaaa
    26881 tagcgtcaaa ccaatcctga tagcccagct caactaaaag cggtaaatcc ataaagaaaa
    26941 tagcctctgt ttgagatagc tcctcttttt gcttggctaa ggcttcccta atgatagcat
    27001 tctgctgctg ggaagatttc gccatatttt ccgaatgagc aaacagcagc tccgctagct
    27061 taggtctgtc taattgcccc gatggcaata aaatatcctg tccaaaggtc tctagtagga
    27121 cctgataaag cttgccgccc tttttttgca gctcatgcac cacctgatcc gcatcaatca
    27181 cctggtagcc tgcttgtctg ataagtgcga cagccgttga ttttccggag gcaatacctc
    27241 ctgtaatgcc aattaccttt gtcattgctt ctgacaccta ggacagacat gtgtccctct
    27301 tcctccaacc ttgagcttta caatggaggt cccgcagcgc tgacagggct tgcctgtttg
    27361 gccatagacc atcaaataat gctgcatact accattcatt cctaaggtat tctgataggt
    27421 tctaaccgtc gagccaccct tttcaatacc taattgtaaa atacgaatcg tttcatcatg
    27481 aatccgtttg atttctgcct ttttcaggct agcagatcga cgctcagggt gtactctagc
    27541 tgcccatagc acctcgtcca catagatatt tccaagacca gccactaaag tctgatccaa
    27601 aagatgaggc ttaatggtct ttttagaggc tagcagagca gcctcaaagg tcttcaattg
    27661 aaaggtctgc ttcgtcggct caggaccaag ctgacgcttc tggaaaaaag cagccagctc
    27721 agcctttggt agcaaatcaa aggttccaaa ctttctcaca tcttggtaaa ccagcgtgga
    27781 gccatcagtc attgtcaaaa agacatgaaa atgcttatgc tcaggtaccg tatcaggaaa
    27841 caagaggtat ttcccctcca tacgcaaatg cgagatcata accagctggc caaagtcaaa
    27901 gagcaggtac ttcccgcgac gatctacccc ttgcacctgc tgcccaggga tcgtcatcac
    27961 aaaatgctca aggtctgttt tgaccatctt gggcacccta accgtcactg ctgcaatctg
    28021 cttgccaacg actaagcgct caagcccgcg tcgcactgtc tcaacctcag ggagttcagg
    28081 cataattaaa gataccaaac gcgctaacaa agaaaccaca taaccaaaac cagcagaacc
    28141 agccagtttt agcactcttt actcagtctc aatgttacaa acacgcttcc tttctataag
    28201 ctactattag aaagccccac ccaaaacctc aataagcttg agcacaaagg actatccttt
    28261 gataagaact gttatcattc ttattttacg cataatccat aaagaaagca actctcacga
    28321 acagcctttg cagtcactgc cgctatagca tcagaaaagc acatctcgcc cgccaatcca
    28381 gcaagcaaag acaaagcccc tgagctagcc tattgtttgc cagcccaagg gcacgttgtg
    28441 gcctttagtg tctgtaaata gaaaaccaag caatgctgca agcctcaact gacaatgcta
    28501 ggtctgatca gtcctgtcat cagcttgcgg ataatctata ctaattggcc tatcaacaag
    28561 acggatacta tcctggtaaa caccttctgt ttcaaaaata acaatgtcat ttaatccctt
    28621 gttgaaatag ccctttggaa tataaagggt taataaggga cccacttccc aaaaacgacc
    28681 aatagggtga ttgttgataa agacacaacc cttcccaaag ccagtcatat caatatagct
    28741 tgcctcaggc tcatgacatt caaattgata atgataaaag ccgggctgcc cctcgtaaaa
    28801 atcgccatca aaacaaagct gagacaaatc atcaagcggc agacaataca tctcccaatt
    28861 ggtcacaaag tgcaagtcag ccatcatacc acgtcctaga cccttacttt gactaggtgc
    28921 tgtcagcttg tgcccataat tgacccggcc catattttca attaaaacat cgacctgact
    28981 caaggcatgc tgctggttaa tgatgatatc atcaccaatc gtctcctgat actgtgttgc
    29041 aaccttttga ccatctaaaa agacctgtgc tctatctcta ctatcaatca agcgtaaacg
    29101 ctcgtcctca cgcttatcct tcaaaagatg tgtccgatac aggatatagc ccgttgattg
    29161 ccctaaagcc tctatgttac taggatagca agcagtctga cagctgctga tgtgctccag
    29221 cgtgctaaac agactaacct tgtccttcag accaatcaga ggcagtgaca tcaagggctt
    29281 aatcaaggga ggagtaacct ctatctctga aagctccgcg gtcagacgct tttgaatcgc
    29341 gtaaaactta gctgtcggat tgccagcctc atctaggata gcgtcataat cataggaggt
    29401 cacctgcgga aggtccaatt gctttctggc agagcagcca ttcataaacc caaagtttgt
    29461 tcccccatga aacatataca ggttaatact gccctgcgcc aaaacctcca tcactgcgtc
    29521 agctcgctct tcagggtcgc gtttgatgat gggctcatgc caacgattga accagccgtc
    29581 ccaaaattcc atacacatta aaggccaatg cttgccatgc tcagaaaaga aggcctgcat
    29641 gtcagcaaaa ttctcctgtg cccttgagcc aaagttgcca gtcacaaaga catcatcttc
    29701 aatcagacta ccagctctaa gagtggctcg ccaaggacca tctgctgtaa acaagggcgc
    29761 actgaggtgc tcctccataa agcccttaac agctgttaaa taggccttat cctctccata
    29821 ggagccatat tcattttcaa gctgaaacat caaaatattg ccgccctgct gccattcatg
    29881 ccttgctagt ctcggcagca gctcctcata atagcgcctc acataggcta aatagacagg
    29941 atcagacgac ctgatatgac aattctttgt cagcagccaa gcaggtaggc caccaaattc
    30001 ccattctgca caaatataag gactaggtct gacaatagca tagagcccca attgctgcgc
    30061 cagcgtcaaa aaggcttcca catctaattg gccagagaaa tcatagcttt cctccctagc
    30121 ctcatgtaaa ttccaaggga cataggtctc aaccgtatta aatcccagtg cctttaaatt
    30181 ataaagcgaa tgataccaat catctgggtg aattctaaaa taatggatag cccctgacag
    30241 gatttgcagc gatctaccat ctaaataaaa ctgatctgaa atctgaaaac gttccaagct
    30301 taattcctca cttattattg ctattagcct actaggcctc attgctgagc ggcttggaat
    30361 ggcctattct agcaacagcg aacaggccat tcagcagaca ggctaactta tcttatggta
    30421 acaattgtaa acactatcta cagtctgact cctcatgcta tgctgtcaca gcagcaggat
    30481 aagagacagt gtatgccttg tcatctgtca atctaatccc atatttggtt tcaacaatag
    30541 tatggtcaaa ctgcggtaaa acagttatcg gtccttcagg catactctcc agagacaatt
    30601 caaatatcgc tgtgtctgtg ccatctcctg aaacatagct ggcaagctta tctacgccat
    30661 ttacagtaac tgctaactga cgatcaccaa gaataaacat cggttgatta aaggtcatct
    30721 gaatggttat gcttactttg ccattttgct ttggagctgc tgacgttatt gttacttctt
    30781 caatttcagc cttatcctca cgaaactggt ctgagatcat ctgcttgata ttaaaggttg
    30841 aataggtgat ctgaccacta tattcgtata acaaaccaac cctctcgtcg tctagttgaa
    30901 ccaagctaga gtaagcaaaa cgctttggct caaaaatggt tgaagcgacc caatgaatgc
    30961 tatcgtcctc taagacctca ccgacacgca gaatcccttt catgcgctga tttctaatcg
    31021 tcagttgctc acctgagggc tctcctaaag gattggataa aacaacatat tctttgccat
    31081 caaccatcat atgaatagct gacaaattga cataaggctc tgggaggtct gtgattgtag
    31141 gattatcgtc ccaagtcata ccatagtctg tgcttctggc aataacgatt gtctttccgg
    31201 tattgcgcat aaactgtaat aagtgaccat tgtttagctg aatgatttga ttttctgtca
    31261 attctgtgac tgatgtatca aaatccttag aggttgtttg ttggttatga ccataaattc
    31321 tgccatcatt tggtgattca cctcgttgcc atgtttgacc gccatcatca ctaaaaatat
    31381 tagcactgct ttgacgacct agactagctg atgtcgcatt ttgttgattg gtatagtaaa
    31441 tcgggaaaac taaccgtttc acctgctcac cctctgcatt gactgcgtct atttcaatgc
    31501 cagctgcggc acccgtacct aaaaatccca tccagtcttc ttttatttgt ggggtaatat
    31561 caagaggtgt ggaccaggtt tgcccttcgt cttcactggt tagcagccat aaaaagctgg
    31621 tcatgtaagt aaatagagga gctgtttgtg agccttctct agtgatgcct tgcttagtgc
    31681 gaccacttct cagataaata ttccctagta gaatatcctc tcctgcctct gtttgataga
    31741 ggttgccgcg tgtgctaaag gctgtctcaa aattgccctc atcaacatac atatctgtct
    31801 gatggccact ctggtcatag acgataccac cttcacgcac agtgtattta ttattgtcaa
    31861 aatcataaag atttaaataa tactgaccgt taatcaattc atatcctgag cctgctttag
    31921 aagcaacagc accctgtgac tcaggaaaga catctaccag caaataaagc ttgccagaag
    31981 cgtctgttag caaggtggag tctattgaaa aagcagattg agtcatgttg gtattccaat
    32041 cagccaagct atattgtgtt gtaaaataag gctgagttgg catatctaag accgtaatgt
    32101 tattactcca ggttttgcca tcatcatggc ttatcctgac aacagttgca acatctcccc
    32161 agtcattgta gtgcttcttt cttgcatctg ctgcggctat caaggttcct gatggcgttt
    32221 tgacaacaga gggaatccga tattcaaaga ccccttcatc atatttgtcc caaacattcg
    32281 tcttttcacc agtaactggt cgaagggttg gctgatgagc cttggcaata tctgtcagat
    32341 catacacatc tgtatcaatc agcacctgat caaccagtcc ctttaacccc cagtgaagga
    32401 ccgactcacc atcataggtg cgtttcaagc ctccaattgt tagcgtatca gcagaagcct
    32461 tccaaggtaa ttgcttcata aacccagcaa agtcagcttc cccatataag tcaccattca
    32521 agtaaatctt tagcctagac cctgtaaaga catagctgat cgtctgccag tccgagttcg
    32581 ttaataaatt aaagcctgag ccaactttta caatcggaac ctcagctcct ttaaattcaa
    32641 gacctatttt attgttttta ggctcgataa agaaagaggc gtattcatta gctgatgctt
    32701 gatttgagat cgataacaag gccaagggcg atgagcttct cactgttgta tcagcagtat
    32761 ctagacggta tctgattgtt acagttcctt gggttaggtt catcacatcg tctagcttac
    32821 caagagcctc gtcatctgtt acggctgctt tttctgctgt tgcgtccaaa atagcattgc
    32881 ctaaatcaac taaaatggat gcttgatctg agattggctg atctgagata tagcttgctt
    32941 ctatgcttgt ataaacagct cgtccgcctt ctgtggtgta tttgatctga taatgctctg
    33001 cacttcccaa gatctcctct ggcgtaaccc attgccaatt ggctggcagg gctactgtag
    33061 ataagggttc tcccttctta ccaatcagac cttctttagg taatacagtt aaaatagcta
    33121 cttctcttgc aatcttagca gttggtgtta ctgttgagcc taaatcagca ttgtaaggaa
    33181 cagcactata gtaaatgtta taaataccag gagctagctc agacaaggct gacaaatcat
    33241 ctcgaccagc agcctgtaaa gcagcattgg tatttccacc cttgttagta aacaagtatt
    33301 cattttcaac tgaaaaatca accacatagc cttcctgatc agtggttaca gcttgagcta
    33361 aatcaggact ggttccctct agcatggtca aatccttgac ccccttgaga actggctgtg
    33421 aggcataata agcttctgag gctgcttttt gctcagcatc ttggtaataa cgcacataat
    33481 caatcacaaa ggccgtctca tctgaagcta gatagtagcc tgcattttta ctccaattgc
    33541 ctccagtagc aaggttaaac tgaaggtatt gaggcttatt aaaggcagct gcggcagcct
    33601 ctaagcgatc atcaccggtt aaatacatgg tattataaac aatcccatca acataccatt
    33661 caatcttatc cggataccaa ttaataccaa agatatggta gtcatcataa aagtcatcac
    33721 ttaatgtcag attgccaccc aatgctgttg ggctatagct tccatctttg tctgcatcac
    33781 ccttgatata gtaaaaatga ggggtcccgt aaactgtttt gttgctttga tcaccttcgg
    33841 caagctcacc ctcatgctct ccgttaggag caccgattag ctccataatg tcaagctcac
    33901 ctgtgcttgg ccagccatag ccttgagttg acgcaatatc accatctaag gtaaaatcag
    33961 cccccaatgt ccaaaaggct ggaaaggctc ccttaccctt gggaagcttg gccctagctt
    34021 cgatacgacc atataaaaat tcttgcttgc caaccgttcg tacgcttcct gaatcataaa
    34081 tgacctgacg tgcgcttgtt cctcctctag gattggcata acggtcctcc ccataacgct
    34141 ctgtgacgtt taaaacaaga ttgccattat caagatagac attctctgtg ctgtctgtgt
    34201 agtgctgctg ctcattcccg cgaatacttc ccaattcata tccccagttc tcttggttta
    34261 accgatctcc tgaaaactca tcctgccaaa tcaattcata atcattttcc tctacgacac
    34321 tcacgttatc aatactagca gaggcagcca aggcttccgg agaagaggct tccaaccatt
    34381 tgactaagcc aacaaaggtt tctgaagtcg ttgctgtaaa ggagagcttg atatgtgacc
    34441 aagtaccgtc tgtatctgtg aggctgacct ctttgataac agggccctga agattgtgat
    34501 tggactcttt agcggtaagg tataagccat tatgaggtgt gtcagcttca accttcacat
    34561 cagcctctag cgtataggtt ttcccaaccg ttgtagacac cttttgaagg atatgctcat
    34621 ctaaagtgcc gcttgttacc tcagcatagc tattaccatt ctctgttgtg aggactgaat
    34681 gacctccctc tctatattgc cactgattct tattggacac ataatcattg tcaaaaccac
    34741 cattagccac cttattgagc tcaatcggag cgttagactt ctcttcgtct gctgtctgat
    34801 cagcagcatt gctggtcaca gcattagcta ctactgcctc atctactgtc gtctcctctg
    34861 agactactaa ggcctcgcta tctgtatctg tagcttgagg ctcctgctca tggcttatct
    34921 ctgttactgc tgctttcgta ggctgctgca ggcttacctc tgaaacgtca tcagcataaa
    34981 cagccactgg cagaccagca gcaagaccaa tacccacaca cactgaagca acaccgacac
    35041 taagcttttt gatggcatat tttctaattt gctcttttcc gataggatta aataacatgt
    35101 ttatttcctc acttatatat acatcatttt taaacacaat agcttttcaa aggcccattt
    35161 agcctaatcc agtgctggtc aggctaacga ccttgttata aaaacgcttt caattcagcg
    35221 cttaaaagaa gatataccag atgaaaccga tatatcctct cacaaagtga ctaacctgcc
    35281 ttttcaagct cattatcagc catcttaaca aatggaaggt aaatcagggt tgccaaggcc
    35341 aaattgacaa gcgatagcac aatagcacgc caatcaaaac cagttgaaaa gaagccatac
    35401 aagacaggcg gcattaccca ggtcacattt tgcgtaacgg gtgcaaccaa gcccagacta
    35461 gttgcgatat aagcaacact tgacataaca gcaggacaaa caataaacgg aataaacaac
    35521 aaaggattta aaacagttgg taaaccatac atcactggct ctcctatatt aaacaataca
    35581 ggagcaacac ctagcttagc cacctcacga tagtgttcat ttttagactt ccagaaaata
    35641 gcaatcaaga gccctaaggt tgcataccat acaaagaaca ctcgtccaaa gataaggaat
    35701 cgcctcatgc ttttgataag cctccaaatt agccaagagg gcaacaccaa atactccctc
    35761 catatttggc gccataacat tgccgccatg aatcccaaag aaccagaaaa attgggtcaa
    35821 aacagctacc aaaacaacag caataaagct ttgtgataag cccaaaagtg ggatttgcaa
    35881 gaccttatag atccaatcaa tcatcaaaga acccgttagc ttttcaaaga caaatgttaa
    35941 aatagctacg ctatacaagg cgcaaaagcc tggtatgata gataagaagg gcttggctac
    36001 agcaggtggc acactatctg gtaatttaat tgtccaattt tttaacatta atttacaaaa
    36061 aataatagag gctaaaaagc caatcataat tgctgtaaaa taaccattgg agttaatttg
    36121 cgcaccaggc aataggcctg agatggtcac attaagtgag ctgccgctga cagtaacacc
    36181 actgtcctta aaagccgtca caagatcaac acccttgaga cctgacgcgt caatgctaga
    36241 ggtaacagaa tccccaatcg caatcacaaa ggcagctaaa gaaaccaaac ctgatgagag
    36301 cgtatctgtc ttataaagtt tagcgacatt aacccctaag caatacacaa atagcaagga
    36361 cacaatcgaa atgcttccct taaagacaag gttgttgatg gttacccacc attggaaggc
    36421 ctctgtaatg ccttgcaagc caaattggtc tggaatatcc actaaaaagg cattgatcaa
    36481 cagggcaata gagcctgtca tcacaaccgg catcgttgca ataaaagaat ctcgcaaggc
    36541 cactaaaaat cgttgattac caatcttcgt agcaattggc agcagctttt gcgaaagaaa
    36601 gttcatatag ttattcattc atagctcctt aaaacaatca taaaacagct aagatagagc
    36661 agtaaaggct ctctctaaca gcttagcctt catttttagt ttgctcgctc gcctgccatc
    36721 ttctttccac attaataata aacggcaagt aaagaagaat atctagaata attaaaacaa
    36781 gctgtaggac tgaggcttgc cagctgcccg ttgccaaaaa tcctgaaata acaggcggca
    36841 tggtccaccc cggatcagca taggtgccag gtacaatgcc agaagcaaag gcaaaataag
    36901 cgacaaacaa attcataaca ggtgctagta caaaaggaat aactgtcaat agatttaaaa
    36961 caaccggtaa gccaaacatg gtcggctcgt taatgttgaa aaaccctgga atcaaggtca
    37021 atggtgacaa gacctttgcc tgctgactag ccttgcgacg acgtgctaac caggctaaag
    37081 ccaacaccaa gccaatggtt gcaccagctc cgccgataaa aacaaagtta tccataaaga
    37141 cagacgtaaa gacatgcggc aattcctgac cagccttatg agctgccata ttttcagtca
    37201 agttagataa ccagatcggc ttcataatag gattgtttag gacatttcca ccatgcacac
    37261 cacagaacca taaaaagcca ttaagaagaa caacgataaa attaccaaat aaggtacttc
    37321 ccagcaagcc aaatggaact cctagtacgg acttaacaat gtcatggaca tttggcaggc
    37381 taaaatgatc caagaaagca taaacagcaa gccaaaacac aataatcacc gctccaggaa
    37441 taatggcgct aaagcttttt gatactgcag gcggcacacc ctcaggcatc ttaatccgaa
    37501 tatccttttt cataaaccat tgataagcat agccatttac caatcccaaa acaatggcaa
    37561 caaacaagcc gcctgatgaa aggtaagaag gcgcaatacc cgctacctca cccaaggctt
    37621 taccagattc attgacaaat gaaacagtaa atggggtcac tgttaaaaag gcagagatat
    37681 taataatccc agcagaaatc ccgtctgcct tatactgctt agccaagcta taagaaatcc
    37741 caaaggccgc aaccaaggca atcagattaa agctcgaatc tactcccttc cacagatagg
    37801 tagagacacc aatctcacca agccaagctt cccaaccagg aatcggcagg ctagcaatca
    37861 ccattaaaaa ggacccaatc aaaatcaagg gcatagcgta ggtgatccca tcacgaatag
    37921 caataagaaa gcgattgctt cctaggcgac cagcaactgg aacaagcttt tgctggataa
    37981 aatcttcaaa tttagtcatt gttacctcct tgtgacgtta acctttcata aatagatact
    38041 agctcccttg ccaaatcaac aaaggtaata ctagtcatca aatgatcctg accatgaact
    38101 aatagtaggc ttactggtgt agcatttccc cgtgcctctt gagttagcat atctgtttgt
    38161 gcatgatggg cctgcaccaa tgccttatcg gcctgcttta gactttcctg agcttgattg
    38221 agctctccct ttttagcaaa agcaatcgcc tccatcgcaa gcgacttggc actaccacca
    38281 tgcatgatca ggcccataat cgtctctagc tgcttatctt ccatgaccac cacctatttc
    38341 atcaaacttt cagctaaggc aataacctta tcaccattca tcataccgta atcaaccatt
    38401 ggcacaaccg ccactggaat gtccttttct gccaagcttt cttgaaatgc tgacaattga
    38461 taagcaacct gtggccctaa taacaccaca tcaacaggat ggcttagagc gtaatcctct
    38521 gcctcagtca atggcaatgc aaaaatatct gcctcaagcc cccgattgtc agcagccttt
    38581 tccatctttg tcactaatag actggtactc atacccgctg cacaggccaa cataatttgt
    38641 tttttactca tgatcttctc ctttatccca aatcctaacg tcgaatagag cgcgacattc
    38701 tcacaatggt atgtcttttt cctcggatag cgtcactaag agcaaagata ttttccactg
    38761 gcgcaatccc gctatagcca gcatctccga tatgatgaat atcgacacca cagattttat
    38821 tgcgaatagc aatgtctcga acgatcgtag tatctgaccc ttcctgactc gttccaatag
    38881 ctgacataac tagagcatcg tgagcatgca cctcctcaac aatagctcta aggtcaccct
    38941 ctgtaaagcc aggaactgtc ccaacagcag gaactaaaat cacatcagcc ccagcctcga
    39001 taaaccgccg aacagtttct aagtcaatca ccgcttcatt agagccagca gcatgcatct
    39061 ttccagcaat aatcaagcct gaaaaatagt gcttggcctg ttgaatagct ctttcaatct
    39121 gattattgct aacaccagta cctggatttc ctgtcaagca aacaaagtca aagcccaagg
    39181 cttcaatctc ttgaaaggtc ttagctgtcg cctgtcgccc ttctactagc tccaagcgct
    39241 tttcagtcat gtcaacgtcc aaatcaattg gttctaaatt aacaccaatt ggacgcccca
    39301 ccagacgacg cagctctaaa ataggctgat cagtagcagg tagaccagat atttgaacat
    39361 caaagacatc tacacaattc agcaaaatca aatcagcact aaaggctgcg gcaacctcag
    39421 cgttcgtaag gtcatctcca gtccaagagg gtcttggcgc tacattttct gagacaatgg
    39481 tacgtccctc gcttgcctta atggcttgct ttagctctaa cgatgttaac tgtagcattt
    39541 ctgagctact agcactcaat aatcgtgttt tcatcgcttc tcctttattt ttattttaaa
    39601 aacattaaca aaagataaat aagatttaac tcttatttgt ttacttttta taaacaaata
    39661 aagtgtattc tatttaccaa tatttgtcaa cgttttcagg caggattttt aattcttttt
    39721 tggtatgata gaggtacgat aatagaggtt actatgaaga cggataaaca acaagagctt
    39781 tacgcaaaaa ttttagatac catttatgcc caacggccta tttcacgcat tgatatttca
    39841 aagctaacgc acatcacacc tgctacagta ggggctatca ctaaagagct gctagcacag
    39901 gggtggatac acgaaatcgg agagctgacg gaccactccg ttggccgcaa aaaaatatta
    39961 cttgatgctt cggctaacgc cttttatttt gctggtgtcg aattgtccga aaagcatttc
    40021 tatttggtca ttacagataa cctgggcacc atctatgcca agcacaacca acagatcgac
    40081 ccaagcattt cctcctacta caaagcagac tatatctctg agctgattca agccttcctc
    40141 aagcagcaca agcactatga tgtacaagcc ataggaatag cactgcctgg gcattacgat
    40201 cattccacct ccagctcaac gcatattaac accaacaatc ccatctggca gcaggtcgat
    40261 ttaaccgcaa ttgcgaagtc cttccctatt ccagtggtct ttagcaacaa tgctcactgt
    40321 atgattattg ccaagcgctt atacgagcgt caggcacata atcacaattt tattttcttt
    40381 catgtcggac gaggcatgca ctgctcctat atgtataagg gggtcattta tagccgtcac
    40441 aatgctgttg ttggggaaat cggacatacc attgtcaacc ccactggaga gctttgtgaa
    40501 tgtggcaaaa aaggctgttt acagacctat gccagcaatg cctggttgct caaaaaagca
    40561 aaactgctac atcagtatgc ccccaattct catctaagaa gccttgtcga taaggcctgt
    40621 gagctcaagc tagaccatct cttgattgcc tatgagcttg gtgatgtcgg ggtgaccacg
    40681 ctcattcaca cagctattga ttaccttgtt ttatccctgt ctaacctctc cttactgatt
    40741 gataccgagc aaatctatct ccatggcaga tttatcagcc atcctcttat atcctccaaa
    40801 attctgcaag ccctgcaaaa tgacattaag cttcttagca atcaaaaaaa gccagaaatc
    40861 attgtcatgc ctttttctgt ctataatgcc gctgtgggag ctacaggctt atgtatagat
    40921 gagctttacc tcaattataa aaacaaatat gattgataac ccccacacca atatcagcta
    40981 aagctttaaa gcccatttga gaagctattt ctcaagtggg cttttgcatt atgcgacttt
    41041 cagtccatct cgctccgcag gtgcgagaca aatgataacc ataaaaaaag agaggcactt
    41101 ggttctctct gttctatcct aatgccccat ttgaaactca ccagcaaaat actctgccag
    41161 catcagtcta tgcttgtctg agattgaaga cagctctgca atctcttctc tagaaaaata
    41221 accgagcctt aaggtttcat cattttgata atcagtgata gccttatctg ccttggctat
    41281 aacctcataa agcatcacaa cggtctgaac cttatcacca tttggatagg tctcttcaaa
    41341 attggtataa acattcaaca accgtaaagg ctctactgta atccccgtct cctcataaaa
    41401 ttcacgcctg caggtttcag cagaagactc acccagctcc atggcacctc ccggaattgc
    41461 ccaggttttc ttatctgcac gtagctgcaa aagcacctta ccttcggcat tggccaaaat
    41521 accaccagca aaagtcagaa taatgttatc atgccccacc tttgagcgaa tataggaaat
    41581 atagtcctgt gtcatcgtaa ctcccttcat tgccatcata agattaaagc cagtcagctg
    41641 gcgcaattgc tgcttttttg ccaaccaata agcaatgcag gctttgtctc ttgtccttga
    41701 taggctggca aagcatatag ccctaatttt tcaacctgat tatatcacac tttttaaaag
    41761 ccagaaagag actcgaatgc caagtccctt ttctttcaat ctataaccaa cctcagaaaa
    41821 actcagacaa gctacgataa cttttttaat gtcttctttg gccaatggtt tgcgactggt
    41881 cattgaatta ctttcaatat tatccccatc atcacatgat aaccacaaat aaacacgtac
    41941 ttgtgtcatt gccttctcct caatcagtag taggtaccta ctgttttttt gattgattgt
    42001 acctataggt gtttttttcc ttcaaaatct ttaaataaaa taccctttat aa
//
LOCUS       DARYUW010000010        41446 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYUW010000010 DARYUW010000000
VERSION     DARYUW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41446
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(19..1290)
                     /locus_tag="TVW11_000479"
     CDS             complement(19..1290)
                     /locus_tag="TVW11_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1364611.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TVW11_000480"
     CDS             complement(1283..1891)
                     /locus_tag="TVW11_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1364612.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TVW11_000481"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TVW11_000481"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1364613.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TVW11_000482"
     CDS             3817..4287
                     /locus_tag="TVW11_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1364614.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TVW11_000483"
     CDS             4289..4633
                     /locus_tag="TVW11_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1364615.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TVW11_000484"
     CDS             4650..5078
                     /locus_tag="TVW11_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1364616.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TVW11_000485"
     CDS             complement(5276..7813)
                     /locus_tag="TVW11_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1364617.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8376..9329
                     /locus_tag="TVW11_000486"
     CDS             8376..9329
                     /locus_tag="TVW11_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1364618.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TVW11_000487"
     CDS             9329..10075
                     /locus_tag="TVW11_000487"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1364619.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TVW11_000488"
     CDS             10324..11328
                     /locus_tag="TVW11_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1364620.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TVW11_000489"
     CDS             11625..13811
                     /locus_tag="TVW11_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1364621.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TVW11_000490"
     CDS             13889..14710
                     /locus_tag="TVW11_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1364622.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TVW11_000491"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TVW11_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1364623.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFSVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17043)
                     /gene="sezV"
                     /locus_tag="TVW11_000492"
                     /pseudo
     CDS             complement(15860..17043)
                     /gene="sezV"
                     /locus_tag="TVW11_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
     gene            17293..18897
                     /locus_tag="TVW11_000493"
     CDS             17293..18897
                     /locus_tag="TVW11_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1364624.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLSDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGRDDY
                     YNLLMRLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDRYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19120..21339
                     /locus_tag="TVW11_000494"
     CDS             19120..21339
                     /locus_tag="TVW11_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1364625.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21354..21797
                     /locus_tag="TVW11_000495"
     CDS             21354..21797
                     /locus_tag="TVW11_000495"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1364626.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21924..23216)
                     /locus_tag="TVW11_000496"
     CDS             complement(21924..23216)
                     /locus_tag="TVW11_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1364627.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23971..24819
                     /locus_tag="TVW11_000497"
     CDS             23971..24819
                     /locus_tag="TVW11_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1364628.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24969..26102
                     /gene="ugpC"
                     /locus_tag="TVW11_000498"
     CDS             24969..26102
                     /gene="ugpC"
                     /locus_tag="TVW11_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1364629.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26286..27905
                     /locus_tag="TVW11_000499"
     CDS             26286..27905
                     /locus_tag="TVW11_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1364630.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28014..28376
                     /gene="traF"
                     /locus_tag="TVW11_000500"
                     /pseudo
     CDS             28014..28376
                     /gene="traF"
                     /locus_tag="TVW11_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28490..28849
                     /gene="yajC"
                     /locus_tag="TVW11_000501"
     CDS             28490..28849
                     /gene="yajC"
                     /locus_tag="TVW11_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1364631.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29023..29772
                     /locus_tag="TVW11_000502"
     CDS             29023..29772
                     /locus_tag="TVW11_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1364632.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29782..30576
                     /locus_tag="TVW11_000503"
     CDS             29782..30576
                     /locus_tag="TVW11_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1364633.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30608..31873
                     /gene="rseP"
                     /locus_tag="TVW11_000504"
     CDS             30608..31873
                     /gene="rseP"
                     /locus_tag="TVW11_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1364634.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32143..33999
                     /locus_tag="TVW11_000505"
     CDS             32143..33999
                     /locus_tag="TVW11_000505"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1364635.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34051..34608
                     /locus_tag="TVW11_000506"
     CDS             34051..34608
                     /locus_tag="TVW11_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1364636.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34943..39340
                     /locus_tag="TVW11_000507"
     CDS             34943..39340
                     /locus_tag="TVW11_000507"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1364637.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39462..39890
                     /locus_tag="TVW11_000508"
     CDS             39462..39890
                     /locus_tag="TVW11_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1364638.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40020..40565
                     /locus_tag="TVW11_000509"
     CDS             40020..40565
                     /locus_tag="TVW11_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1364639.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40744..41358)
                     /locus_tag="TVW11_000510"
     CDS             complement(40744..41358)
                     /locus_tag="TVW11_000510"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1364640.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
BASE COUNT        11514 a         8303 c         9922 g        11707 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaagctt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gtcattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tgaaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggca atgatagaat
    16381 aattttttca gagcgcagcg tatcaccact caccacaggg ataaaggtat ttcgtagact
    16441 gaagatgatt tccttgagct tgtgcacatc accctcttga acaatgctag ataaattttt
    16501 ctcataattg tagagacaaa ccttagattc ctgcttcttg acaaacatat tggccttttg
    16561 cacctcgata ttgtcggaaa aatccctaat atagtgacgt aaaggaggtg ataacaaatc
    16621 ctctatcttg ccggaaaaga agtaatggac cacaatcaag aggtcacgaa tagcattcaa
    16681 aggataaaca ggtaaatgct ttagcgcttg gtaaagaatc tcttcttctt ccttagtcaa
    16741 atccttatca gcaacggcca ccttaaaaaa ggtcttatcc aaaacattac agcgccaagg
    16801 gccaattaaa atataatgat cctgataacg gtatattaaa aaaagctcat tatagcttcc
    16861 ctgaaagaaa agattggttg cctgttcctt gtccatttgc ctaagcactg cttgaaaacg
    16921 ataataaaat tcaaaggtat catcattcca aaagctttct gtcacctgat ggtccttatc
    16981 aaatactgta attgataact tcaaacagcc ctgtagagat tttactaacg acatagtatc
    17041 catgctaagc gtcaccccct tcataatcct cacggtatct tattctatct taaaatttaa
    17101 gaaaagcaag gatatgcact tataatgaaa aaatagacat aaaaaacaat aatatacatt
    17161 cttgcttatt aaataaaaat gacaatgtac tgcataaaga agttcctgtc attaaaataa
    17221 aagtgccatg aggttataat agtatggtaa aacaaaaaag tgtgcccata acgggtagag
    17281 aggaattgac atatgttttt gagaaataac aagcaaaaat ttagcatcag aaaactaagt
    17341 gccggtgcag catcagtatt agttgcaaca agtgtgttgg gagggacaac tgtaaaagcg
    17401 aactctgagg ttagtcgtac ggcgactcca agattatcgc gtgatttaaa aaatagatta
    17461 agcgatatag ccataagtag agatgcctca tcagcccaaa aagttcgaaa tcttctaaaa
    17521 ggcgcctctg ttggggattt acaggcatta ttgagaggtc ttgattcagc aagggctgcg
    17581 tatggtagag atgattatta caatttattg atgcgccttt catcgatgtt aaatgataaa
    17641 cctgatgggg atagaagaca attaagtttg gcttcattac ttgtagatga aattgaaaag
    17701 cggattgctg atggagatag gtatgcaaaa cttcttgagg ctaaacttgc agctattaaa
    17761 tctcaacaag aaatgcttag agaaagagat tcccaacttc gaaatctaga gaaggaaaaa
    17821 gaacaagaac tacaaaaagc taaagatgag cgtcaagctc ttaccgaatc attcaacaaa
    17881 actttatcaa gatcaacaaa agagtataat aaactaaaaa cagaacttgc aaaagaaaaa
    17941 gaaaaagcag ctaagatgac taaggaatta gcagataagc taagcaatgc tgaagcaagt
    18001 cgtgataaag cctttgcagt atcaaaagat ttagcagata aactaagtag tgctgaagca
    18061 agtcgtgata aagcttttgc agtatcaaaa gatttagcag ataaattggc agctaaaaca
    18121 gcagaagctg aaaagttaat ggaaaacgtt ggtagtctag accgcttggt agagtctgca
    18181 aaacgtgaaa tggctcaaaa attagcagaa attgatcaat taactgctga taaggctaag
    18241 gctgatgcag agcttgcagc tgcaaatgac accattgcat cacttcaaac agagctagaa
    18301 aaagctaaga cagagcttgc tgtttcagag cgtttgattg aatcaggcaa acgtgaaatt
    18361 gctgagctac aaaaacaaaa agatgcttct gataaggctt tagtagaatc acaagctaat
    18421 gtagcagagc ttgaaaaaca aaaagcagca tcagatgcta aggtagcaga gcttgaaaaa
    18481 gaagttgaag ctgctaaagc tgaggttgca gatcttaaag cacaattagc taagaaagaa
    18541 gaagagcttg aagccgttaa gaaggaaaaa gaagcgcttg aagctaagat tgaagagctc
    18601 aaaaaagctc atgctgagga actttcaaaa cttaaagaaa tgcttgagaa gaaagaccat
    18661 gcaaatgcag atcttcaagc agaaatcaat cgcttgaagc aagagctagc tgacaggatt
    18721 aagtcattgt cacaaggtgg tcgtgcttca caaacaaacc caggcactac aactgctaaa
    18781 gcaggtcaat tgccatctac tggtgagtct gctaacccat tcttcactat tgcagctctt
    18841 actgtcatcg ctggtgctgg tatggctgtg gtgtctccta aacgcaaaga aaactaagct
    18901 atttcctctt tccccaatgg acaatagccg aaataataga gcgactatcg ttctaacaca
    18961 aaagcaacag tctcctgtct gttgcttttt gtgatattag ggctcatcag tctaggctaa
    19021 tggttttctg cgctttatct gcagctttga ggattccttc ttttgctttt acagtgaaag
    19081 tgttaaaata ggaaaaacaa ctagtaattg aggaagtaaa tggttaaaga aatcaattta
    19141 tcaggagagg aagtagttgc ccttgctgcc aagtacatga cagacggtga cgtcgagctt
    19201 gtgcaaaagg cgcttgatta tgcgacagct gctcattttt accaggttag aaagtcgggg
    19261 gagccttata ttgtgcaccc tattcaggta gcagcaatcc tagcagacct gcatttggac
    19321 gctgtgacag ttgtctgtgg ctttttgcat gatgtggtag aggatactga tattactcta
    19381 gaggacattg agtttgactt tggtaaggac gttcgtgaca ttgttgatgg ggtcacaaag
    19441 cttggtaagg tagaatacaa gtctcacgag gagcagctgg ctgaaaacca ccgcaaaatg
    19501 ctcatggcca tgtcaaagga cattcgtgtg attttggtca agctagccga ccgactgcac
    19561 aatatgcgca ccctcaagca cctccgtaag gacaagcagg agcggatttc tcgtgaaacc
    19621 atggaaatct atgccccgct agcccatcgc ttggggatca gtcggatcaa gtgggagctg
    19681 gaggatctag cttttcgcta cctcaatgag atcgaattct acaaaatctc tcatatgatg
    19741 agagaaaagc ggcgggagcg cgaagctttg gttgatgata ttgtcactaa gattaaagcc
    19801 tacaccaccg atcaagggct ttatggtgat gtctatggcc gtcctaagca catctactcg
    19861 gtttaccgga aaatgcgtga caagaaaaag cgctttgatc agatatttga cttgattgcg
    19921 atccgttgtg tcatggagac acaaagtgat gtttacgcga tggtcggcta tattcatgag
    19981 ctctggcgtc ccatgcctgg ccgcttcaag gactacattg cagcgcctaa gaccaatggc
    20041 tatcagtcga ttcacacgac tgtttacggg ccaaaaggac cgattgaaat tcagattcgg
    20101 accaaggaaa tgcatcaggt cgctgagtat ggggtagcag cccactgggc ctacaaaaaa
    20161 ggtattcgtg gcaaggtcaa tcaagtcgag caaaaggttg gtatgaattg gattaaggag
    20221 cttgtcgagc ttcaggctgc ctcaaatggc gatgctaagg gctttgttga ctcggtgaag
    20281 gaggacatct tttcagagcg tatctatgtg ttcacaccga caggagcagt gcaggaattg
    20341 cccaaggatt caggccctat agactttgcc tatgccgttc acactcaggt tggtgaaaag
    20401 gcgacaggag ccaaggtcaa tggccgcatg gtgcccttga cagccaagtt aaaaaccggt
    20461 gatgtggtgg aaattgtcac caatccgaat tcctttggtc ctagtcgtga ctggattaag
    20521 ctcgtcaaga ccaataaggc tcgtaacaag attcgccaat tctttaaaaa tcaggacaag
    20581 gagctgtcta tcaataaagg acgtgagctt ctggttagtt attttcaaga gcagggctat
    20641 gttgccaaca agtaccttga gcgtaagcgt attgaggaga ttttaccaaa ggtcagtgtt
    20701 aaaagcgagg agtctctcta tgccgctgtt ggctttggcg atattagccc agtcagtgtc
    20761 tttaataaat taaccgaaag agaaaggcgt gaggaggagc gtgccaaggc taaggctgaa
    20821 gctgaggagc tggttaaggg cggtgaggtc aagcatgaaa acaaagagat tctcaaggtc
    20881 cgcagtgaaa atggcgtgat tatccaaggg gcgtctgggc ttctcatgcg tatcgccaaa
    20941 tgctgcaatc ccgtaccagg agatgtgatt gaaggctata ttaccaaggg acgaggcatt
    21001 gctattcacc gcgcagactg taataacatc aagagtcagg acggctatca ggagcgtctc
    21061 attgaggttg agtgggattt ggagcattct agcaaggatt accaagctga gattgatatt
    21121 tatggtttaa atcgtatcgg cctgctcaat gatgtcctgc aaatcctatc taacgccacc
    21181 aagagcattt caactgtcaa tgcccagccg accaaggaca tgaagtttgc caatattcat
    21241 gtgagctttg gcattcctaa tctggctcag ctgacagctg ttgttgaaaa ggtcaaggcg
    21301 gttccagatg tttacagcgt caaacgaacc aacggataaa aaggagacca accatgaaaa
    21361 ttgtgattca gcgcgtcaag gaagcctcag tgtcgattga tgggaaaata gctggcgcta
    21421 ttgatcaagg gctgctgctg cttgttggca taggtccaga tgatcaggca gaggatatag
    21481 actatgcagt gcgtaaaatc agtcatatgc ggattttttc agaccccgag ggcaagatga
    21541 accgatccat tcaggacatt gagggcagtg tcttgtctat ctcgcagttt acgctatatg
    21601 ctgacaccaa aaagggcaac cgacctgcct tcaccggggc tgctaagcct gacagggcca
    21661 gccagcttta taacagcttc aacgctcagc tagagcagct tgtaccggtt cagcgagggg
    21721 tctttggtgc ggacatgcag gttagtctga tcaatgatgg cccagttacg attatcctag
    21781 atacgaagta tcgataactg cctagcgatc gatcgtttgc ttaggagagt catataaagg
    21841 aaaaacaaaa agacgagtgg tatgagaagc actcgtcttt gtcgtttatg ctgctgtgtt
    21901 gaagctagct agggctacta gtcttatttt tgcaggtctt tgtagactgc gatgaattct
    21961 gtctcagaaa ttggggttaa gctgccagtg aattggtaag aagtaccatt tttagcttgg
    22021 aaagtattag gtaaaccttt aaggtatttg tcgatagtct cagtggtaat tgcttcgtgt
    22081 gttttaaagg tgtattcgtt aatcagctgc tgctgtttgt cctgttggta aatagtaact
    22141 gaacgatagg ttgtgctata gtcatcgtta atatccttag aaataaaata ggtttctaca
    22201 acagaatctg aatgtgtcgc atagctaatg ggattgttga cgtcatactt tgaattatat
    22261 acttgagcta tcctgttaga atctatgata tagttaaagt cctcatcgcg atcagcatgg
    22321 tagaccatgc gttcactagc tccactgtaa atctcaccgt tatggctttg atgagttata
    22381 tcaggatcct gcgtgactgt tgtactgatt cgcttgacga gctgataccc gtctttgaaa
    22441 gcctgagtgg tttcaaaagc ctttttagca gcttcaaaga gctcctcaga agagaccctg
    22501 ctgccatagt atcttaaccc ggtaagtcct tctttaccaa ggctgtcagt tacatcaaca
    22561 ttaacaagct gcccattgtc ttttttgagg aatttaacgt gctgtgtcac agctacggca
    22621 tctgaatctt ggattgggtt tcctgcctta tctgttacct taatgtcctt gagagctacc
    22681 ttgctaactt tttccacaag gacctgaccc gtcaagatgt atgtttggtc tttttgatga
    22741 tactgtcctt tgattggtgt cgtaaaatgg tctgtgctaa gtatttcagc tgtagaagct
    22801 tttgttaatt tggcattttt caaactaatg accttaaagc tttctgctga aggatctatg
    22861 acgtcttgaa ctagctttat catctcattt gtggtgtagg ttttgccata ttctagtcta
    22921 atatcctgat aatgtggaga tacgatggtg tgattagtgt tatctactcc agtgatattg
    22981 accatgaggt acagtcctgt ggtttcttga tagtcttttg aatggattgg cttagtggtg
    23041 tcctcgtatt tatagtgatt tgctacccta ctagagcttg accatgccca cccaactttg
    23101 taatggtttg ctttaacggc aggtgctccc aaggtcatgg tgaatagtcc aatgactaca
    23161 gttcctattt ctaaaggtgt tttcccaagg tgatacagtc tttttgaagt caacatattt
    23221 caaacctccc taaatcctgt cagtctctat agttataaaa atacagagaa tcgttagaag
    23281 aattaatgtt tcatgccggc aagatgagtg taacaaaaga ttggtgccga tacaagaaga
    23341 tggagattag agcatctggt ttcaatgaga gttacataat agcagaaggt tttttcacta
    23401 tgagagctaa tcgtcttaaa atggtataat agcaagtgaa taggctatct aactggttta
    23461 acagccattt ttagagaagc ttaatagtat tgctgataag tgactcgtat ctccatattg
    23521 cttttcaaag gctatgttag ctatgataag cgtgaccagg ctatcggaaa atccagtgtt
    23581 cttaaaggct ttgaagctct ggctttgaac cttagctctg gtgtttctat gaaaatgact
    23641 tgggccttgt accagataag aatgaagtca aattgaggtt ttttgacaaa atgtttgagt
    23701 aaatacaagt tcatagaagt ctaatgtata aaaatacaat tgtatcgcca taatctgaat
    23761 gaccaaacca ttaaaaaaat aaaattttta aacattttgg aaaacgcttt caaaactaaa
    23821 aagaactgtc ctatagtcat tgcttagcat taaagcaagg tgtgaaatgt tatcatatgg
    23881 agaaataggc tgtcttgtgc tgtatctgtg ccaaaaaaga atgcttgttt ttgtgatata
    23941 atgtgactaa gaaacctgaa aggaatgctt atggcattaa aagactattt tcctgatatg
    24001 caagagggtg catttcctct ggctgaccaa gattggatta gcgttgaggt tggggagcag
    24061 tacctccatt tccccaaatc cagcttgtca gagcgagagc agcttttgct tggtttgggg
    24121 cggcagcgca aagagccgtc caaggatcag aaatctcctt ggtatcatta tttgattctg
    24181 ggccaagggg agcagccgga ggagtttcag ggttgccagt tcatctatat caaccatcaa
    24241 tgtcctttag caggtgattt gattgagctt ctaaagggga tcatagaggg agttgaggct
    24301 gttttgccca ttagccagac caggacagct tttttggtct gtcaccatag ccgttcagac
    24361 ctttttcagc tcttagcaaa tttattgccc acgattgaga gcgattttgg tttggccttg
    24421 atgattttta tcggtaatgg ctggtatcag gtgtcaggaa atgccttgag agactatttt
    24481 aaggaagaaa atgctgtgtt tacagcttat cttgctgagc actctgccag tcgcttgctg
    24541 accttttcag aggtcatgct ctggtcactc ttagcaaaca gtggtttgcc agccttgtca
    24601 aagcatttta gtcagctgct tttagccaat aaagaggtca tggatctggt gctcgccatg
    24661 tggcaggagc atggcaacct ggtacagaca gcccagcgct tgtatattca tcgcaattcg
    24721 ctgcaatata agctggataa gtttgctcag cagtcaggtc tctatttaaa gcagctagat
    24781 gacttggcct ttgcttatct atttatactg aagcattaga tttgtgcagg gtgcccaaag
    24841 acatttgggc gttttgtcta tatgatgaaa acgctatctt tgctataata aaagcatcaa
    24901 ataaaaagtg tcagggttgc tagcattgca gtcagctagc agcctatctg acccattagg
    24961 agtaacgcat ggttgaatta aacttaaagc acatctataa gaaataccca aataccacac
    25021 actatgctgt tgaggatttc gatttagaca ttaaggataa ggaatttatc gtttttgtag
    25081 ggccttcagg ctgtggtaag tcaacaacgc ttcgtatgat tgctgggctt gaggatattt
    25141 cagagggtga attgaaaatt gacggtgagg ttgtgaatga caaatcacca aaggaccgcg
    25201 atatcgcgat ggttttccaa aactatgccc tttacccgca tatgaccgtt tatgacaaca
    25261 tggcctttgg tctcaagcta cgtaaataca aaaaagatga tattgatcgt cgtgtcaagg
    25321 aagcagcaga aatccttggc ttgacagaat ttttagaacg taagccagca gacctttctg
    25381 gtggtcagcg tcagcgtgtg gctatgggac gtgctatcgt gcgtgatgcc aaggtattct
    25441 tgatggacga gcctttgtca aacctagacg ctaagctgcg ggtgtcaatg cgtgctgaaa
    25501 ttgcgaaaat tcaccgccgt atcggctcaa caacaatcta cgtaacgcac gaccagaccg
    25561 aagcgatgac cttggcagat cgtatcgtta tcatgagtgc cactaaaaac cctcaaggca
    25621 acggtacaat cggaaagatt gagcaggttg gctcaccaca ggagctctat aacctaccgg
    25681 ccaataaatt tgttgcaggc tttattggaa gccctgcgat gaacttcttt gaggtggttg
    25741 tcaaggacgg tcagatcatc agtgaggacg ggcttgatat tgctattcca gaaggtcagg
    25801 ctaaaatgct tgaagcagct ggctataagg gcaagaaggt tatttttggt atccgtccag
    25861 aagatatttc aagcaaccaa atcgtgcatg acacctatcc aaatgccaat gtcacagcag
    25921 aggtcttggt ttctgagctg cttggatctg aaaccatgct ttatgttaag cttggtcaaa
    25981 cagagtttgc ttcacgagtt gatgcgcgtg acttccacaa tccaggtgaa aaggttagct
    26041 tgaccttcaa tgttgctaag gggcatttct ttgatctaga aacagagcaa gctattcgct
    26101 aataacacct cctagaataa aatcctcatc ttgcttgagg attttttaac aaaagaaaat
    26161 gcaagcgatt gcgctatcaa aaagaaaaag ggatttatca taaagacaac agatgttctg
    26221 tagtgctagg cgatcataat gatggcacga aatagcagga gactgtttag taataaggag
    26281 atatgatgga aaaacactgg tggcataaag cgacaattta tcaaatttac ccaaggtcct
    26341 tcatggatac aagtgggaat ggtattggtg atttaaaagg aatcacaggt aagctggatt
    26401 atctacagga gctagggatc acagctattt ggctgtctcc agtttatcaa tcaccaatgg
    26461 acgataacgg ctatgatatt tcagactatc aggccattgc agctattttt ggtgatatgg
    26521 ctgatatgga cgagctgctt gatgaggcca agcagcgggg gatcaaaatc atcatggatt
    26581 tggttgtcaa tcacacctct gatgagcacg cttggtttgt ggaggcaaga gaaaatcctg
    26641 acagtcctaa acgagattat tacatttggc gtgatcagcc taataatctc atgtcgatct
    26701 tttctggctc tgcttgggaa tatgatgatg cctctgggca gtattatctg cacatattca
    26761 gtaaaaaaca gcccgacttg aattgggaaa atgctgaatt gcgtcaaagc atttatgaca
    26821 tgatgaattt ctggattgat aaggggatag gtggctttcg catggacgtc attgacctga
    26881 ttggtaagat tccggattct gaaattacag gcaatggccc aaggctgcat gaatacctca
    26941 aggagatgaa ccaggcaagc tttgggaatc atgacctgat gactgttggt gaaacatggg
    27001 gcgctacacc ggaaattgct cgtcagtatt cacgtcctga aaataaggag ctgtcaatgg
    27061 tctttcaatt tgaacatatc ggcttgcagc ataagccaaa tgcttctaaa tgggattacg
    27121 cagctgagtt gaatgttccg gctctcaagg agatttttag caagtggcag acagagctaa
    27181 agctaggtga aggctggaac tccctttttt ggaacaatca tgacttgcct cgtgtcgtct
    27241 ccatttgggg aaatgataca gtatatagag agaagtctgc caaggcaatg gctattttgc
    27301 tgcatttaat gcgtgggaca ccttatattt atcagggtga agagattggc atgaccaatt
    27361 acccctttga gcgcttgagt gatgtgaatg atattgaatc actgaattat gccaaggagg
    27421 ctatggctaa tggcatgtca gaggaggctg ttcttgattg tatttgtagg gtgggtcgag
    27481 acaatgcaag aacaccaatg caatggagca gtcaaaagaa cgccggcttt tcaactgctg
    27541 atcagacctg gctgcctgtc aacccaaatc atcaagagat taatgtggct agtgctctag
    27601 ctgatcctga ttctgttttt tacacctatc aaaagcttat tcagctgcgt cagacacagg
    27661 attggctggt ggaggcagat tatcagctgc tggaaacatc agataaggtt tttgcctata
    27721 agcgtcagct tggtagagag acttaccttg ttgttgtcaa tctgtctaat caagagcagt
    27781 tttttgaaga aagtcttcat aaggcccaag tgattatcag caataccgat gtgcaggcag
    27841 tcgtagaaag tcaacagctg gagccttggg acgccttttg tgttaagctt gatgagacct
    27901 tgtagcctag ctgcttgctg tgcctcagct caataatcgt agcgattctt tgagaatttt
    27961 gacaaattgc tgtatgatta gtagaagaat tagatacaaa agaggaggct gagatgaccg
    28021 ttgaagaaac catgaccttt gcaaaaagca ttgcagcatt tagataggta gagattagtg
    28081 aggtagtcac taggctagca gcaggtgagg acatcaccgt ctttttaggc agagcgacct
    28141 gtccttattg tcgtcgcttt gcacccaagc tagcaagcgt agcaaggcag gagcataagg
    28201 atattttctt tgtagatagt gaagactcaa cagagcttgc agacctgcag gcctttcgtg
    28261 agcgctatgg gcttgctact gtgcctgccc tgctcattag tcgtcatcag gaggtcaagg
    28321 cagtctgtga ttctagcttg actgaggaag ccattttggc tttcctagag cagtgacaga
    28381 cagctaatta tctggtgcaa gtaatagaaa tgtaatcagt catgtcttgc tatgtgagtc
    28441 caaatctgct atagtaggac atgactttta gacgaaataa ggagatatta tgggcttacc
    28501 aacaatttta atgtttgttg tcatgattgg tttaatttgg tttatgcagc gtcagcaaaa
    28561 aaagcaggcg caggagcgcc aaaatcagct taatgcgatt gaaaaaggcg atgagattgt
    28621 gacgattggt ggcatgtttg cagtggtcga tgaggttgat ttagcagcaa agcgaattgt
    28681 cttagatgtt gatggtgtct atctgccatt tgagctatca gcgatcaagc gcgtggtcga
    28741 aaaaggaagt gcagtgacat cagctgatgt ggatacgaca gagactgcag ttgatgacac
    28801 agcggttgag gcttcagacg aagctgaatc agctattgag acaaattaag aaaatgaggt
    28861 ctgaagcatt agtgtttcag acttttttag gtgatgatag caggtagcca gacagagctg
    28921 tcatgtgcta tggaaatatc gtctacaacg agaaaaagcg agccaaaccg catgaaatat
    28981 ggtaaaatat gaggtaagta tgcttgtgaa taaggaaaaa acatgtttgg attaaaagcg
    29041 aagtcaaaaa aaatcgtttt ggataggatt ccaaagcaca ttgggatcat catggatggt
    29101 aatggacgct gggcgaaaaa acgcttaaag ccgcgtgtct ttggacataa ggcgggtatg
    29161 gacgctttgc aggaggtaac gattgcagct tcagatttag gggttaaggt gttaacagtc
    29221 tatgcctttt cgacagaaaa ttggtcaaga ccacaagatg aggtgagctt cattatgaac
    29281 ctgcctgttg agttttttga taagtatgtg cctgagctgc acaaaaataa tgtcaaggtg
    29341 cagatgatcg gtgagaccaa ccgcctacct aaggatacac taaaggcctt ggaagcagct
    29401 attgctaaga caaggcaaaa tactggcttg attctaaact ttgctcttaa ttatgggggt
    29461 cgcgcggaaa tcaccaatgc tgtcggtctc attgctcaag atgtcctaga cgccaagctg
    29521 aaccctggtg acattaccga ggatttgatt gccaactatt tgatgacgga tcatttgccc
    29581 tatctctatc gcgatcctga ccttattatc agaacgagcg gtgaattgcg cttgagtaat
    29641 tttatgcctt ggcaatcagc ctatagtgag ctttacttta cgccggtgct gtggcctgat
    29701 tttaaaagag ctgaactact aaaggccata gaggattata accatcgtca tcgccgtttc
    29761 ggtgctattt aaggagagag tatgagagaa cgtttcattt ggggtggtgt tgcagctgct
    29821 gttttcctac cctttttact cattggcagc ttaccctttc aattgtttgt aggtgtgctt
    29881 gccatgattg gtgtatcaga gctgttaaga atgaagaggc ttgaggtctt ttcctttgag
    29941 ggtgtttttg ccatgctagc agctttcgtt ttgacagtgc cgttggatca ttacctgacc
    30001 tttttgccga tggacgctag ttttgcttgt tacgggctgt tggtgttttt ccttttagca
    30061 ggaatagtga ttagcagcga ttcttatggc tttgaggatg ctagctttcc gattgcagct
    30121 agcttatatg ttggtattgg ctttcataat ctggttaatg cgcgaatgac agggatagac
    30181 aaggtttttc tggctctttt tattgtctgg gcgactgata ttggagctta cttgattggg
    30241 cgccgatttg gtaagcgaaa gctcctgcca aaaatatcac ccaacaaaac aattgagggc
    30301 agccttggtg gtatagtcag tgcggtgctt gtttcctttg tgtttatgct ctttgataag
    30361 gctgtttatg ctcctcatca ttttggaaca atgttgattt tggtggctct tttttctatt
    30421 tttgctcagt ttggagattt ggttgaaagt gctgtcaaaa gacatttcgg agttaaggac
    30481 tcaggcaaat tgattccagg ccatggtggt attttagatc gttttgattc gatgatcttt
    30541 gtttttccca ttatgcatct atttgggtta ttttaaagct cattatcaat agactgaaag
    30601 gaaatctatg ttaggaataa ttacctttat tattattttt ggtattcttg tgcttgtcca
    30661 tgagtttggc catttctatt ttgctaaacg atctggtatt ttagtcagag agtttgctat
    30721 tggcatggga ccaaaactct tttcgcatgt tgatcagcaa ggaacgcttt acacgatccg
    30781 gctattaccg cttggtggct atgtgcgaat ggcaggctgg ggtgatgaca caactgagat
    30841 aaaaacagga acgcctgcta gcttaacgct taatgatcag ggcttggtca agcggattaa
    30901 cctgtctcag agcaagcttg atccgactag cctgcctatg aatgtgactg cttatgactt
    30961 agaagataag ttgacgatta cagggctggt tcttgatgag atcaagacct attcggtaga
    31021 ccatgacgcg accattgtcg aggaggacgg tacagagatc cggattgcgc cgcttgatgt
    31081 tcagtatcaa aacgcaagca ttggcggtcg tttgatcacc aattttgcag gacctatgaa
    31141 taattttatt ctaggtattg ttgtctttat tttgtttgcc tttgttcaag gtggtgtggc
    31201 tgattatcat agcaaccata ttcgtgtggt ggaaaatggc gcagcagcca aggctggtat
    31261 tagagacaat gatcagattt tagagattaa tcatcaaaag attaatgact ggtatgagtt
    31321 gacgcaggcc gttactgatt cagcagcaga tgttaaggct aagggcaagc tagagattac
    31381 ctatcagaca ggtgatcagg ttaagactat agcactgaag cctgaaaaaa aaggcgatca
    31441 gtaccttatt ggtgtccagt acccactaaa aacaagtctg acagacaagc taataggtgg
    31501 ctttgagatg gctggtaatg gtgctctagt gattgtcact gctctaaaga gtttgattac
    31561 ctcctttagc ctagataaat taggtgggcc agttgccatg tatcagatgt ccaatcaggc
    31621 agcaaagaat ggtttagagt ctgtcttgtc cttgatggca atgctctcta tcaatttagg
    31681 gatttttaat ttgattccga ttcccgcact agatggtggt aagatcctga tgaatgtgat
    31741 tgaagcactt cgtcgtaagc cattaaagca agagacagag acttatatta cccttgcagg
    31801 tgttgcgatt atggtggtac tcatgattgc agtgacctgg aacgatatta tgcgagcctt
    31861 tttccaaggc tgatggtctc tctcatttaa aggagagcct aaaaggctta atgtaacaga
    31921 aataacaaga gatatagtgt cattattgtg gttctaagac cttgcaaatg cagcaaaagc
    31981 ttagccaata tagctcattt tgtctctttt ttagaaatga attctcaacg aaaggaaaga
    32041 gagctgttga ccaagctggg ctaaggccta cagctgaaat caaaatgcta gacctgctat
    32101 tagtctaagg gcgttttgag ctgctctcta tagcttattt taatgaaaca aagtaaaatg
    32161 cttatcccaa ccctgcgcga aatgccaagt gacgctcagg taatcagtca tgccctcatg
    32221 gtgcgtgcgg gctatgtccg tcaggtatct gccggtattt atgcctattt gccattagct
    32281 catcgtacaa ttgaaaaatt caagacgatt atgcggcagg aatttgacaa aattggtgct
    32341 gttgaaatgc tagcacctgc ccttttaaca gctgacctct ggcgtgaatc aggccgctat
    32401 gagacttacg gtgaggacct ttacaagcta aaaaaccgcg acaaatcaga ctttatctta
    32461 ggtcctaccc atgaagaaac ctttactaca ctggtgcgtg atgcggttaa atcctataag
    32521 cagctgccgc tcaatctgta tcagattcaa tccaaatatc gtgatgaaaa gcgtcctcgt
    32581 aatggcctgc ttcgcacacg tgaatttatc atgaaggacg gctatagctt tcatcaaagc
    32641 tatgatgatt tagatgtcac ctatgacgcc tatcgtcagg cctatgaggc tatttttacc
    32701 agagcaggct tggatttcaa aggaattatc ggtgatggtg gtgctatggg tggtaaggat
    32761 tcgcaggaat ttatggctat cacaccggac cgtactaatt tagaccgctg gctggtctta
    32821 gacaagtcta ttccgtcatt ggctgacatt ccagaggagg tcttggaaga gattaaggcc
    32881 gagctggctt catggctggt ttcaggagag gacaccattg cttattcaag tgaatcaagc
    32941 tatgctgcta accttgagat ggcaaccagt gagtacaagt cctcatcaaa ggtaacagcc
    33001 ttagatgatc tcgtcgagat tgagacacca aattgtaaaa ccattgatga agtggcggcc
    33061 tttcttgacg ttgctgagca tcaggtcatt aaaaccctgc tctttatggt ggaccatgag
    33121 cctgtgcttg ctttattggt tggaaatgac cagatcaatg ctgtcaaatt gaaaaaccac
    33181 ctcggtgcag acttcttaga gccagctagc gaggaggagg cgcgtgctat cctaggtgca
    33241 ggctttggtt cacttggtcc agttcatttg acagatggta tccgtattgt ggctgatcgt
    33301 aaggtccaag accttgctaa tgctgtagct ggagccaata aagatggtta tcacctgact
    33361 ggtgtcaatc caaatcgtga tttccaagca gagtatgctg atattcgtga ggtaaaagag
    33421 ggagagacct ctccagatag acatggcgtg ctgcagtttg ccagaggtat tgaaatcggt
    33481 catatcttta agctggggac ccgctattct gatagcatgg cagctaatat ccttgatgag
    33541 aatggcagag cagttccgat tgtcatgggc tgctatggta ttggggttag tcgtatccta
    33601 tcagcagtca ttgagcagca tgctcgtctc tttgtcagca agacaccaaa gggtgattat
    33661 cgctatgctt gggggattaa tttccctaaa gagctagctc cgtttgatgt gcatttgatt
    33721 accgttaatg tcaaggatca ggaggcgcag gacctgacag aaagagtaga ggctagtctg
    33781 atggccaagg gctatgatgt cctcactgat gaccgcaatg agcgtgtcgg ctctaagttc
    33841 tctgatagtg atttgattgg gcttccgatt cgtgtgacga ttggtaaaaa agcagctgag
    33901 ggcattgttg agatcaaaat caaagcaaca ggtgacagca ttgaggtgca cgctgatagc
    33961 ttgattgaaa ctcttgacat tctcacaaag gacaactaat gatatgaggt caacgatggt
    34021 tgatctcttt ttgtatgcta taatgaaagc atgacaattg aggaattaca gcagctggtg
    34081 ctagcagatc atgagctaat gactattcta agcattatag agaccttgcc tttaaaggat
    34141 tgttggctgg cagcaggtgc aattcggaac gctatttgga atcatttagc ttatgggata
    34201 ggctttgatc cgctgacaga tgtagatgtg gtcttttttg accctgagat ctcttacgaa
    34261 gctgagcagc tgctagaaga gcagcttaag tgtgcttatc ccatgtacca atgggaggtt
    34321 cgcaatcaag cctatatggc agcacataac cccaagacgc ctccttatcg atctagtcaa
    34381 gacgctatca caaagtatcc ggagcgctgt acagcgattg ctgttagact tgtaggagga
    34441 cagctagagg tttttgctcc ctatggttta gcagacatta gtcactttgt ctgtcggcca
    34501 acaccgcatt ttttagagga ttcagagcgt atggactgct ataggcagcg cctagcaaag
    34561 aaggactggc acaagaaatg gccacagctg acctaccacg actgctaagt cagaggaaac
    34621 aaagcaggct aggagctccg tacagccaag caattagtcc gctcccagac ccgttagcta
    34681 cagctctcac ctagtcaaaa caagcacatg aacagatcat tggcagatag ccttgccttt
    34741 gcagatattg tcacacccta tttagctgta ccatgtgtct tatgataggc gtgatagtgc
    34801 tgtcagaagc gccagctgag ccagaaaaag cgttaagcct acagcaaggg gcttttaacc
    34861 tttggtatgt tgtcttgtag gagaggtcga aaatgatcac tatttatgat aaaatagacc
    34921 ctaagaaaat caggagaaag ctatgtcaga tttattcggt aaattgatgg aacaaattga
    34981 aatgccactt gagataagac aatcaagtgc cttttcgtct gctgatatta tcgaggtcaa
    35041 ggtgcattca gtgtctcgtc tgtgggaatt tcatttttcc tttgcagagg ttctcccgat
    35101 agagagctat cgagagctgt cagataggct tgtgagaacc tttgaggcag cagatattaa
    35161 ggtaacattt gacatcaagg cagagacaat taattattcg gatcagctgc tgcaagccta
    35221 ctatcaagaa gcatttgagc atgagccctg taatggggct agcttcaagt catctttttc
    35281 tagacttcag gtcaggtatg accatcatca gctgatcatt atggcacctg actttgtgaa
    35341 taatgatcac tttaggaaaa atcatttacc caatctggca gctcagtttg agcgctttgg
    35401 ctttgggagg ctagcgattg atatggtgtc tgatcaggag atgacagacc atttgacaaa
    35461 ggactttgag accaaccgtc aggctctggt ggaaaaggct gtacaggata atatcgcagc
    35521 acagcaatca ttggaggcca tgcagccacc agctgaggag gcagcaccaa gcccaagcct
    35581 tgactataga gagcgtatgg ctcagcgcca agcaagcttt gataaggcgg tcattacacc
    35641 aatgattgag gtggatacag aagaaaatcg cattgttttt gaaggaatgg tctttgatgt
    35701 ggagcgcaag acgacaagaa caggccgcca tatcatcaac ttcaagatga cagattacac
    35761 ctcctccttt gccatgcaaa aatgggccaa agatgacgat gagctcagaa aatttgatct
    35821 gattgcgaag ggagcttggc tgcgcgttca gggaaatatc gaaaacaacc ccttcaccaa
    35881 gagcctaacc atgaatgtgc agcaggttaa ggcgattgtt caccatgagc gtaaggatct
    35941 catgccagaa gggcaaaagc gtgttgaatt tcatgcacac actaatatgt ccacaatgga
    36001 cgctctaccg acggtagaag acctgattga tacagcagcc aggtggggac atcaggcagt
    36061 agcgattact gaccacgcta atgttcagag ctttccgcat ggctatcata gagcacgcaa
    36121 ggcaggaatc aaggcaatct ttggcttaga ggccaatatt gttgaggata aggtacctat
    36181 ttccttcaat cctgtcgcta tggacctgca tgaagccacc tatgttgtct ttgacgtgga
    36241 gaccaccggc ctttctgcca tgaacaatga tttgattcag atcgcagctt ccaaaatgtt
    36301 caagggaaat atcattgagc agtttgatga gtttatcaat ccaggccacc ccttatctgc
    36361 ttttacaaca gaattgacag ggattacaga taatcatttg gtaggagcta agcctataca
    36421 gcaggtgtta gaggcatttc aggccttttg tcagggcact atcctagttg cccacaatgc
    36481 tagctttgac gtgggattta tgaatgccaa ctacgatcgg tatggtttag caaaaatcag
    36541 ccagccagtt attgacaccc tggagcttgc cagaaacctg taccctgagt ataagcggca
    36601 tggcttgggc cctttgacta agcgctttca ggttagcctt gagcaccatc acatggccaa
    36661 ttacgatgct gaagcaacag ggcgtttgct ctttatcttc ctaaaggaag ctagagaaaa
    36721 gcatgggatt acaaacctgc ttcagctcaa tacagactta gtggcagagg attcctataa
    36781 gaaagcacgg atcaagcacg ccacgatcta tgttcaaaat cagctaggtc tcaaaaacat
    36841 gtttaagctg gttagccttt caaatgtgaa atattttgaa ggtgtgccta gaattccaag
    36901 aaccgtcctt gatcagcatc gtgaaggctt gctgcttggg acagcctgct cagacggcga
    36961 ggtctttgac gctgttttga cccaaggaat tgacgctgct gttgatctgg ccaaatacta
    37021 cgattttatc gaaatcatgc cgcctgcaat ttaccagccc ttggtagtcc gagagctaat
    37081 caaggatcaa gcaggagttg agcagattat tcgcgatttg attgaggtcg gccgcagagc
    37141 tgaaaagcct gtcctagcta ctggaaacgt gcactacatt gagccagagg acgccatcta
    37201 tcgtgacatt atcgttcgta gtctagggca aggtgccctg attaaccgta ctattggccg
    37261 cggagaggct gccaagcctg tcccgctacc agaggctcat tttagaacaa ccaatgaaat
    37321 gcttgatgat tttgcctttt taggtcagga cttggcctat gaggttgtgg tgcaaaatac
    37381 ccaagccctt gctgatcgaa ttgaaaaggt ggaggttgtt aaggatgatc tgtacacccc
    37441 atatattgat aaggcagaag aaaccgttgc tgagctgact tatcaaaagg cctttgctat
    37501 ctatggcaac ccacttccag atatcattga tctgcgcatt gaaaaggagc taacgtccat
    37561 tttgggaaac ggctttgcgg tgatttatct agcctcacaa atgctggtta atcgctctaa
    37621 tgagcgtggt tatctggtag gctcacgtgg ctctgttggt tcaagctttg ttgcgaccat
    37681 gattggcatc acagaggtca atccaatgcc gcctcattat gtctgcccaa gctgccagca
    37741 gtcagagttt atcacagatg gctcggtcgg ctctggctat gatttgccaa acaaggcctg
    37801 tcctagatgt gggacgctgt acaaaaagga cggacaggat attccttttg aaaccttcct
    37861 tggctttgat ggtgataagg ttccagatat tgatttgaac ttctcaggag atgatcagcc
    37921 caatgcccac ttggacgttc gtgatatctt cggggaagaa tacgcctttc gtgcaggtac
    37981 tgttggtact gtcgctgaaa aaacagccta tggctttgtc aagggctatg agagagatta
    38041 tggcaagttt tacccagatg cagaggttga tcgtctagct gctggtgctg ctggtgttaa
    38101 gcggacgact ggtcagcacc ctggtgggat cgttgttatc cctaactata tggacgttta
    38161 tgattttaca cctgtgcagt ttccggcaga tgatgtgaca gcctcatggc agacgaccca
    38221 ctttaatttc catgatattg atgaaaatgt cctaaagctc gatgtactcg gtcatgatga
    38281 tcccaccatg attcgtaagc tgcaggattt atcaggtatt gatccgatta ctattccagc
    38341 agatgatcct gacgtgatgg cacttttttc tggaacagag gtgctcggag tgactcctga
    38401 acaaattgga acaccaacag gtatgcttgg gatcccagag tttggaacga actttgttcg
    38461 tggcatggtg aatgagaccc acccaacgac ctttgcagaa ttgctgcagc tatcaggtct
    38521 atcgcatgga acggacgtct ggctgggtaa tgctcaggat ctgatcaaag aaggcattgc
    38581 caccctaaaa acagttatcg gttgtcgaga tgacatcatg gtttacctta tgcatgctgg
    38641 tctagagcct aagatggcct ttaccatcat ggagcgtgtg cgtaaggggc tctggctaaa
    38701 gatttccgag gaggagcgca gctcctatat caaggccatg cggcaaaaca acgtcccaga
    38761 ctggtacatc gaatcctgtg gtaaaatcaa gtacatgttc cccaaggctc acgctgccgc
    38821 ctatgttttg atggcattgc gagtggctta tttcaaggtt catcacccca tcatgtatta
    38881 ctgtgcttat ttctctattc gtgccaaggc ctttgagctc aaaaccatga gtggtgggct
    38941 agctgctgtc aaggctcgca tggaggacat cagcaacaag cgcaagcgca atgaagcctc
    39001 aaacgttgaa aatgacctgt ttaccacttt agaaattgtc aatgaaatgc ttgagagagg
    39061 gtttaagttt ggcaagctag acctttacaa gagcgaggca actgagtttc aaattgaagg
    39121 ggatacccta attccacctt ttattgcctt agaaggcttg ggagaaaacg ttgctagaca
    39181 aatcgtcaag gctcgccaag atggtgaatt tctatcaaaa atggaattac gcaagcgtgg
    39241 tggtgcttct gccactctag ttgataagat ggacgagctg ggcattttag gaaatatgcc
    39301 agatgacaat cagctgagtc tatttgatga ctttttctaa gattgcacag ccctaatatt
    39361 gtctatgtta gcttgtcata cagtgaagag cagggcagga aggcttcctg tcctcttttt
    39421 gtcaatacgc aaagaaagcc caaaaaagaa cgaggaaaag catgaatgaa ttagacaaaa
    39481 atcctgcctt aaaggcaatg gttgttttta gaaaagcaca gcgtacctta gatgctcaaa
    39541 gctccgcctt ttttcaaaag gccaatctga ctcctaccca atttagcgtc ttagaggtgc
    39601 tttattccaa aggaagcatg agaattaaca agctcatcgg ttctctcttg gcaacctctg
    39661 gcaatatgac cgtagtgctg aaaaatatgg agagaaatgg ctggatcagc cgctgccaag
    39721 atgctaaaga taagcgtgcc tgcttggtac agctaacgcc agagggcaaa gccttgattg
    39781 agactatcct acctgagcat atcaaacgtg ttgaagccct tttttcagtg ctgacagaga
    39841 ctgagcaaaa acaattgatt acgcttttaa agaaatttaa agaactctaa gcaaatggct
    39901 ttacaggatc tcccaagtag gatataatca ctacatagta caaaaagata ctaactagtc
    39961 ataataagtc atcaagacag cagatggcta gttaccagat aatcaatggg agacaaagca
    40021 tgaaacaaat tttaatcatt aatggttcat tacggacagg ttcatttaat catcagcttg
    40081 ctcaagcggc tgagcagcta cttgaaggca aggcagctgt atcttacttg gactgggaac
    40141 aggtacctat gtttagtcag gatttagaag caagcacccc tgagtcagtg gcaggcgtac
    40201 gagaagccat tcaagcagca gatgctatct ggattttttc acctgtctat aattttgcaa
    40261 tcccgggctc tatcaaaaac ctattagact gggtatcacg cgcccttgat ttgtcagacc
    40321 catcaggacc atcagcaatc aatggtaagg tagttaccgt atcatctgtt gctaatggtg
    40381 ggcacgagca gctatttgcg caataccagg acctgctgcc ctttatccgt acgacagtag
    40441 ttggtaactt taccaaagcc gctgtcaatc cagaagcatg ggcgacaggt gttcttgata
    40501 tttctgagga aacaaggcaa agccttgcag cacaggcaga agcccttctt gaagccattc
    40561 actaagactc tctgagcatt aaacagataa agctgcagct aggatcaaaa agcagctaga
    40621 cacataaaaa gagcttaaac cagaaatgta cggcactcca aaagctagac aaaaactcta
    40681 gcgattgggg tacaggtcaa aacggtttta agctcttttt tagacttatt ttatagtagt
    40741 aacttaatta agaattagca taccctcttt agcctcaaag gggtttttcg cattaatacg
    40801 gtcatagaat aagacaccat taatatgatc aatctcatgc tgaaccacga tagcattgta
    40861 gccctttagc ttaatgcggt gcttttcatt gtgcttatcg taatattcca ctgtcacacg
    40921 cgcatgacgg acgacatagc cttccaccac acgatcaaca gacaaacacc cctcaccgtc
    40981 agcaagagca gcgtcttgaa cagaatgaga cacaatttta ggattataga gcacttcctc
    41041 catgctgtaa gcctccttag gtggattgcc ctcgctgtct tcaggatttg gaaccagaac
    41101 agcgatgata cgctttgaca catcaatctg aggtgctgct agaccaactc ctgctcgaag
    41161 ccctaatttt tctcccatga cagggtcttg agaatgcttt aaaaattgca tcattttttc
    41221 acctaaaatg atgtcatcat cactaagagg aaactcgacc tccttagcca cagcacgaag
    41281 cgtaggattg ccttcgcgga taatatcatt catatcaatg agatgctgtg ctttaattaa
    41341 tttatcttgt gcagacattt tgcctccctt tttttatatt tgataatggc tttactatat
    41401 cacaaaatcc ttatttttaa aagataaggc aggccagtga tgacga
//
LOCUS       DARYUW010000011        41262 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYUW010000011 DARYUW010000000
VERSION     DARYUW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41262
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            399..812
                     /locus_tag="TVW11_000511"
     CDS             399..812
                     /locus_tag="TVW11_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1364641.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1072..1653
                     /locus_tag="TVW11_000512"
     CDS             1072..1653
                     /locus_tag="TVW11_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1364642.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2063..2389
                     /locus_tag="TVW11_000513"
                     /pseudo
     CDS             2063..2389
                     /locus_tag="TVW11_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2458..4461
                     /locus_tag="TVW11_000514"
     CDS             2458..4461
                     /locus_tag="TVW11_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364643.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4458..5066
                     /locus_tag="TVW11_000515"
     CDS             4458..5066
                     /locus_tag="TVW11_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1364644.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5255..7981)
                     /locus_tag="TVW11_000516"
     CDS             complement(5255..7981)
                     /locus_tag="TVW11_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1364645.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7996..9282)
                     /locus_tag="TVW11_000517"
     CDS             complement(7996..9282)
                     /locus_tag="TVW11_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1364646.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9415..10473
                     /locus_tag="TVW11_000518"
     CDS             9415..10473
                     /locus_tag="TVW11_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1364647.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10488..12182
                     /locus_tag="TVW11_000519"
     CDS             10488..12182
                     /locus_tag="TVW11_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1364648.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12209..13600
                     /locus_tag="TVW11_000520"
     CDS             12209..13600
                     /locus_tag="TVW11_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1364649.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13587..13724
                     /locus_tag="TVW11_000521"
     CDS             13587..13724
                     /locus_tag="TVW11_000521"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364650.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13920..16094)
                     /locus_tag="TVW11_000522"
     CDS             complement(13920..16094)
                     /locus_tag="TVW11_000522"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1364651.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16082..16975)
                     /locus_tag="TVW11_000523"
     CDS             complement(16082..16975)
                     /locus_tag="TVW11_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1364652.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17187..18137
                     /locus_tag="TVW11_000524"
     CDS             17187..18137
                     /locus_tag="TVW11_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1364653.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18147..19073
                     /locus_tag="TVW11_000525"
     CDS             18147..19073
                     /locus_tag="TVW11_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1364654.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19157..20602
                     /locus_tag="TVW11_000526"
     CDS             19157..20602
                     /locus_tag="TVW11_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1364655.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20950..21555
                     /locus_tag="TVW11_000527"
     CDS             20950..21555
                     /locus_tag="TVW11_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1364656.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21545..23269
                     /locus_tag="TVW11_000528"
     CDS             21545..23269
                     /locus_tag="TVW11_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1364657.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23269..24753
                     /locus_tag="TVW11_000529"
     CDS             23269..24753
                     /locus_tag="TVW11_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1364658.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24767..28210
                     /locus_tag="TVW11_000530"
     CDS             24767..28210
                     /locus_tag="TVW11_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1364659.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28361..29245
                     /locus_tag="TVW11_000531"
     CDS             28361..29245
                     /locus_tag="TVW11_000531"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1364660.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29371..30144
                     /locus_tag="TVW11_000532"
     CDS             29371..30144
                     /locus_tag="TVW11_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1364661.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30476..31558)
                     /locus_tag="TVW11_000533"
     CDS             complement(30476..31558)
                     /locus_tag="TVW11_000533"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1364662.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31617..32372)
                     /locus_tag="TVW11_000534"
     CDS             complement(31617..32372)
                     /locus_tag="TVW11_000534"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1364663.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32810..32980
                     /locus_tag="TVW11_000535"
     CDS             32810..32980
                     /locus_tag="TVW11_000535"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364664.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            33888..33958
                     /locus_tag="TVW11_000536"
     tRNA            33888..33958
                     /locus_tag="TVW11_000536"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33920..33922,aa:Thr,seq:ggt)
     gene            34486..34740
                     /locus_tag="TVW11_000537"
     CDS             34486..34740
                     /locus_tag="TVW11_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1364665.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34762..35262
                     /locus_tag="TVW11_000538"
     CDS             34762..35262
                     /locus_tag="TVW11_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1364666.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35522..36106
                     /locus_tag="TVW11_000539"
     CDS             35522..36106
                     /locus_tag="TVW11_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364667.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36306..36869
                     /locus_tag="TVW11_000540"
     CDS             36306..36869
                     /locus_tag="TVW11_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1364668.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36882..39533
                     /locus_tag="TVW11_000541"
     CDS             36882..39533
                     /locus_tag="TVW11_000541"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1364669.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39746..40234
                     /locus_tag="TVW11_000542"
     CDS             39746..40234
                     /locus_tag="TVW11_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1364670.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40437..41237)
                     /locus_tag="TVW11_000543"
     CDS             complement(40437..41237)
                     /locus_tag="TVW11_000543"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364671.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
BASE COUNT        11349 a         8285 c         9598 g        12030 t
ORIGIN      
        1 ggaaaggagt gctttcaaat gttatcaggg gagcatgatg gctaaagaga gacctcagag
       61 gaaactcagt ctttgaagca ttaagacagc tttctcatat tggttacggg tattagaaat
      121 gcgcttaatc ggtgtcaaca gttttcgtat taccatttaa gacgtttcga cgacatttta
      181 agacttaaat actgaaagca gctggtaata tgctatactg gtgccagttg ctaaacatag
      241 gaaatattca tgtggacgac agcattgatg aaatatttaa tgcttaggta ctggtagact
      301 tgcttatgtt gaggctgaaa aaattaatag agtttgtgac gcagctattg gaggaatagg
      361 tggcgcactg acttgctaag aaagggcaag gtgttgtaat gcttaataaa atgaagcgac
      421 tacattattt gatgattttt aggctattaa ctggtcagct accagctatt agcttgatgg
      481 ctgttcttct ttcaaaagac attcataggc tttctttggg atcactgatt agttttgcta
      541 tctttgcggt aagcactgct gcttctaatt actatttttc acgagaaatt gcgattgagc
      601 agttgaagga acaaacacgt cccaatctgt tattaactca gatcctgttt atagtggtgt
      661 ttatgattat aggcattgtg tcaatctatt gtggtctaag ctcgtctgag ttttataagc
      721 aggttattgc tgtgatatgc tcttttatat catttgtcac tatgggattg atgatttggg
      781 ggatcagata cgcaaaagct tatcgtcgtt aatagcttga ggtggtactg gtacttgaaa
      841 tcacctcctt aaccagttaa tcataagcta tagcactagg tatcagcctt aaagcgacga
      901 tacctagtgt ttgtgtgctc aaacgcttaa aatagctttt gagggggtag agctgtctat
      961 ctgcaagcga tatgacaacc tatttcattt agggatcagg cttttttact atcagtgttt
     1021 ttgacaaggc ccttgttttg gagtatactg ggaaaactag gagggctatt aatgcgtagg
     1081 attcgtttag caaccttagc agatgctaag gctttacttg atatttaccg tccttatgtt
     1141 gaggaaaccg ctgttacctt cgagtacact gtacctagct tgaccgagtt tgagcgacgt
     1201 ctgtctgaca ttatggtctt ttatccctgt ctagtagtgg aagaggaggg aggcatttta
     1261 ggttatgcct atgctagtcg ctttcatgca cgcgcagcct atgcttggtc tgctgaggtg
     1321 accatttatc tggcccagga ggctagaggg agaggcttgg gatcagcctt gtatcaccgt
     1381 ttggagggtt atctgaaagg tatgggaatc ttaaattgta atgcctgtat cgctagtaca
     1441 gcgcatgcta cgccttatct gaccaatagc agtcaagtct tccatgaaaa actcggttat
     1501 cggttggttg gcagatttca tcagtcgggc tataagttta accagtggtt tgatatgatt
     1561 tggatggaga aactgctggg agagcatgac gtacgccctc gcccagtgat gtcatttagg
     1621 gattttcttt gccagaagca ccagtctgaa tgacacctta taaaagctta gattaataca
     1681 aaaggattag gtcctgtcag aggaagctaa tttttttgta ttgtttgacg agaagttttg
     1741 actgataacc gcaatcataa aaaaactctt caggccctgt tataaaatgg tggtagcagg
     1801 agatggttat gtctgagctt gtcactaggt cagctacagc agtcctagtg tcatagcttt
     1861 aaaaatgaga aaaaagaaat tattttttaa gcttggtctt tttaatatct ttttttgccc
     1921 ttgacaattc tgccaatgag ctgcaaaaaa acttaagctc tttcccaaaa agcttttatg
     1981 atatgataca cttgtgttgt aaaaggatcc tgatactagt taagattttt ttactttatt
     2041 ttaacaaagg agagtacacg acatgaaaag aagtgtaaaa tggtttatga gccttggctt
     2101 ggttggagct ttcgtagttg ctgggatatc taatgttaac gcagagacta ggcaccctca
     2161 tccaaagtat aaggacactt gggaatttgg aattaccagt gctagctgat cttactcaaa
     2221 cgcttttctt ggagttccta ttgggctagg aagtagtgct tctgtgacag acttttgggg
     2281 aaatgtaaat agtaaagata gtcaaaacaa tggttgggct cgtgccggtg taaaaaagca
     2341 gtggaattgg gttcaagcaa agtcatgtta tggctggtat caggtttaat gttttattgt
     2401 acgttttagt ggatgaagat attatcctct tagtcaactt ttctcaagga ggtttttatg
     2461 aggtggagag ctacagttat ctgtattttc gttctgcttt tgacatgttt atcatttggt
     2521 gcggtcaagg agtatggcaa tgatatcaaa taccctgttc aggctgcatt ttcattagtg
     2581 gcttcaaaca aagatgttga taagggacac gttttagaca ggatcgaagc cttagccgag
     2641 caggaacata tccaaattta tcgtccctac ttagatcata ctggtaaaga agccacctac
     2701 ctgtttggga caaatgggaa aaagactgtc tatagcagta atcgcaagga gctcttgaca
     2761 aacgatctta gtggcatgta ctacacgacg aggtctcttc cttcatcatt tgaaaccgcg
     2821 atgactgaac ggggcttgac ctacaaaggt gctgatttac cttggtatct cttgccttat
     2881 tattttttgt tcacaaactt acgatcctta gctatttgga ccctcttttt tgtgtttgcc
     2941 ctcctcttgt ttgctgttaa attgatgtat gctaaaaagt ctatgatact aagaagcctg
     3001 ggcttatttg aacactatag ccgcaaggag ttgctacagg atttgttgct gatgggagct
     3061 agctttgcgg ttagtattct cctcttcatt ctctatcaag gcagtatctc caatgttttt
     3121 gtcaagtcat ttacacttct gatcttgact aatgctgtca ttttattatt gctgatgctt
     3181 gctgttcatg ctttattttt catcaatatc cgttcgttga aggcgctagc cattctaaaa
     3241 aataaacaag caaccccttt ggtcctcttt gtctggttgg tggggatttg tttgtctagc
     3301 gtcatttttg ggctttccct acacaaaagc ttggagacta taggaaaatc tgccaatgac
     3361 attcaagttc taggaaaatg ggataaagct aaggattttg cggaaataac atggctagat
     3421 accttgagta cgcatactga tgacaatcac caaattgata gtgattattt caaggaagaa
     3481 aatcagcgct atcaacattt tctcctgtct ttttctgata atgacgttat ttattcagca
     3541 ctttcaagcc ttaacgaaac caatttacaa tcagctcctg atgacttcaa aaaagagtta
     3601 aagaccaatg gggttgatcc aaggattgcg tcaaaagtcc gttatgtcaa tcagggattt
     3661 atgctaaaaa ataaagacat tttccctaac aatgattacg gaaggccagc agctgatgct
     3721 gtaggagtca tttatatttc taaacatatg atgggagatg ctgacagcat tttaaacatt
     3781 gtcaattatg aatggtttca atatagcagc ctaaaggcta atcaattggt tgttcaagag
     3841 gttcctgacg gacaaaagag ctttctgttt aatcataagc aagaccaaca agacattttt
     3901 gctcagcaag aagaagtgaa tactatatta gtgcagttaa acttttcgtt catgacggag
     3961 ccatcattat tgacgaagtt tggagaaatg gctcaaaaat ctatctatcg tcaggcgctt
     4021 attcgtgatc gattaacaca agcaggcttg acgaatttct ctagtttgac caatgtttcc
     4081 aatcatttga ttttagagcg ccataaaatc ctaagccagc tcatcggaag tgttattgcc
     4141 ttaacggtcc ttgccattgc ccagtgcttt atcatttatg aatacattgt ttctctgatg
     4201 aaacaaaagg ccaaaaagat ttccgtctgg ttcttgatgg ggcaaaaaag ccttgttttg
     4261 attggtagat tgttattgcc cttagctttg tgtttgtttc ttgccatagg aatgatggga
     4321 atccttactg gaaataggct catggtacta ggcattggcc tgctttattt aggagaaatc
     4381 gtttgtatgt ccttttttgc ttatcaggct attttgaagc atcggattca aatcatcaaa
     4441 ggagattttg acatattatg attgagataa aacagctttc caaacattat ggaaaaaaga
     4501 caatttatga caagcttagc ttgacttttg aggccaatcg ttcttatgca cttgtaggtc
     4561 cttcaggatc aggcaagacc accctattaa atgctattgc tcgccttgaa aagccagata
     4621 gtggtcagat tttagtaaat ggtcaagaca tttggagcat gaaagagcaa gattatttta
     4681 aggattattt gggctatgtt tttcaaaatt atgcactgat agaggaagaa acagtctatg
     4741 acaatcttaa aatgctggct cctaaatcta acattgtgga agccttgcat agcgttggct
     4801 tagacagtag ttttctctca cagaacattt atgaattatc aggtggtcag gctcagcgtg
     4861 ttgctattgc acgcctattg ttaaaaaagg cttgcattat tttggcagat gagccaacgg
     4921 gtgccttgga caaggaaaca ggtgatgaga ttattgagct gttgcttagt ttggtgagcc
     4981 ctgatactgt tctgattttt gccactcatg acccaaatgt gtttagccgc gttgatgaca
     5041 tcatcgacat ctgtcatcta caatagaggc aagctctgag acatttagtc tggactgtcg
     5101 agctacagca attagcttga caatgctgtt attcctttgt gtcaggaaga gattgctatt
     5161 cttctataga tttttcgaat agacaatgct gaaagtcctt agcgttaatg ctaaggactt
     5221 ttttgtgatt taggtcaagg tagtggtaat ctggttatag atgagctgat tcactctttt
     5281 tccaagctag ggttaggatt tcgcccttgc caagctcagc tggtaggggt tcatgctgat
     5341 cctcttctag taggctggta acccttgctg tgtggtctgg gattgctagg gtaagagcgc
     5401 aggccttgtc atttgataca ttatagctgc gcgtgattag ggcattatcg gataggcgac
     5461 gcttgaaggc tgtgagagca acgtgatcag ttgctccttt gatgtaagca tattgagctg
     5521 gcagctggcc agaatgcctc ttggtttgcg ccatggtgac tggtacctga gcctcctgag
     5581 ctcgccaata gctggcaaag cgtgtggtag cgttaatgct ttcaaagcta aagctgacag
     5641 tctgttgacc gaggcattga gcatcagggg ttgggaagta gccccaatct ccaagctcac
     5701 cgacgcttcg taggagcgtg atagcgatgg tattggtatc tggtaggatt tcgtattcat
     5761 tgaggccgta attgcctaca gtgacaccag tcctaccatc aaaaaggctg acaaaggcct
     5821 cctgatgctg aggattggtt gggtttttcc agaattgggc attggtatga ttaggccgct
     5881 ttacggtttc aaaaatacta tctgcaaaat ggtggtctgt ctttaaatgg gttgggaata
     5941 gcacgcgcaa gcggtggttt gtcatttgat tgttaaagct ggtctgaaat tgtaggcgtg
     6001 ggctgtcttt ttccatacga ataactgttg ttactgtaaa gggcgctttt tcctgtgagc
     6061 gtttggcctg acgctctcta atgtcaatga cagcctccat ttcagccttt agacgatcat
     6121 ctgtagctaa gggaatatca aaggtctgtg tcaattcgat ttcagcaaga taggctgtgt
     6181 tggtcaagac ccgcaactta cagctccctt gatgagcaag gtaggggcta tcatgatctg
     6241 gctggcgaaa gatatattcg ttaccaatat caccacaatc ctcgtattgg agacagctgt
     6301 caaacctatt gccatttagc ttgtcttcaa tcgttagaag gccatttgct gcgatgatga
     6361 cttttaggaa atcattttca agacagctcc tgtcctgatg aaagagcatt ttgtcagtgt
     6421 cagttgcttg gcaaggctga tcagtctctt ttagtgcaag acattgccat gacatagcag
     6481 aaagagtcag tgggagcctt agctgtacct tgatggcaaa gtaggcttct ctgaaggtgc
     6541 gctctggcag ggcataatca aaggcgatgt ctgtgcctaa gatttcagcc tcctctatga
     6601 tcctgccagc tgcgtcaata acctgaaatt gtggctgtct tgtctctagg tattcctttg
     6661 cttcttgata aacagcttta ggcagtcgtt gcccaaatgg aaaaatcttc catgtcaggg
     6721 tgaggtcgga gaccgttttt ttctcatgac cgcaggtatt gaagaggaca aaaggacagc
     6781 tatcctctgg aaacatggag gtatcaatag cctcagctat ttggttggca gaacgctctg
     6841 ctaagtaagt ccccacctca taggctttat caaagcgagg catcatctcc tggtggacac
     6901 tatcaacact acagccacaa atggagtcat gagggtggtt ttgcatcaat gttttccaag
     6961 catagcgcag ctggtcgtga ggataggtac ctgtgacctc aaaggccatc gtggcaagag
     7021 gctctgtgat attttcaagc tgacgagaca ctctggtatt agcctgcttg aggtaaattc
     7081 tagcagaggc agtgttggct aaggtatacc agccgtccgt ttcttggctg gtcatctcac
     7141 cagacacaat tgagagctcc tcaggcagct cctgacttaa atcagccaaa tagtcctcaa
     7201 agcaagagtg gacaaagtcg taatcagggt agagcttatt tgcaagggca attgccttgg
     7261 taacgtctag ttgaacaggc tggtgatcaa ccccattcat catcagcagg tgcctggtag
     7321 aagcaaagcg ctcagcgtct gctagctttt gatcccagaa ttgtcgagcc tttttctcct
     7381 cggttgggat ttcgttgcca ttgctgtacc aattggcaaa taataagccg agaatgcggc
     7441 tatcatcagg tccctgccag atcatttcag aaaattggga gctgtatttt tcgcttgtat
     7501 ccacttgatt gttaaagcct gtaggcctga taccacgtcc aaaggcagcg gcatttagcc
     7561 ctgcttttcg cattagctgt ggtgtttgtc ccatatttcc gaaggtgtct ggaaaataac
     7621 ccagtggaac gcttgccccc cattgctcac agtcctcttt gccaaccagc atgtttcgga
     7681 cattggactc actgctggtc aaaaaggcgt cctgtaggat ataaaagggg ccaatacgta
     7741 gcttaccagc ctgaatggcc tgtctaatct cggcctcacg cccaggcttg acctgcaaat
     7801 agtcatctag gataatggtt tgcccatcta gatggaagct atgaaaatca gggtctgttt
     7861 taaaaaggtc tagtaaatcg tcaattaact ggatcaagcg catgtggtgc tgctcataag
     7921 ccatgtacca ttcgcgatcc caatggctgt gtgaaatgat atgtactttt ttaggtgtca
     7981 tcactgactc actttctaag ggctaatggt aaagcccaga taatcaagaa gaagctcaca
     8041 aaacatcatg tttgcccatg agaaccattc acgtgtatag tgactcggat cattgacgtc
     8101 aaagccctca tgcatcaggt gggtgcctgc gtcagtagcc accagtaaat caagtatatc
     8161 tgctttatct ttttgatcaa gtgcagttaa gccctgaagg gcaagtgcaa tatgccaaat
     8221 atagtttggt ggcgtgtggg aggagccaat accagaagca gcactgcctt ggtaataata
     8281 aggattttcc gggcttaaaa tggtttgacg agtggctagg taaatagggt cgtccttggc
     8341 acaaaagcca agatagggtg ccgcaaggag gcttggaatg ttagcgtcgt ccatgatagt
     8401 atagtgcccc aggccatcta cctcataggc atagatgatc tctccttggc tgttggttac
     8461 aagagcatgc tcctcaatcc ctttttgaat ggcaagccta agtgcatgag ctctcctagc
     8521 aatcgtttga tccttaaaga gatcagtata gagcccttca agataggata agacgacagc
     8581 agcaaacatg ttggacggca cgaggtagcc gtattggcag gcatcatcgc ttggtctaaa
     8641 gccagaccaa gtcatgcctg tataggcaac aggagctccc ttaccgttgt gggtcaaggt
     8701 atcctcctta cgccaggtgt cgcgctcaaa gctgtaagga gaggcagtgt ggtcttgctc
     8761 tgtgctccag acatcaagga tcagcttgat tcctctgtgg aaatcctcat tgaaatgctc
     8821 tgtacagtct gtctctcggt agagcagata ggctaactgg atcggatagc agagggaatc
     8881 aatctcatat tttcgttccc aaatccaagg tcccatctgg gtgtggtctg cttggtggcc
     8941 cttgctattt tcctcctcgt taaaggcgtt ggcatagggg tcaatgcaaa tgtaacggaa
     9001 ctgacgttta acgagacctg ctatgatttg tctcatgcca gcatctgtct tggctaaaaa
     9061 gagataaggc tttagttgcg cagttgaatc acgcagccac atggcaggaa tatcacccgt
     9121 tagaagaaag ctggtcccat cttcgtcgat ttttagggtc gtttccaagg tgttggcaaa
     9181 gctggcttta aaattaatgg cccagctacg gtgctcttca ccgcagagct cttcaatcgt
     9241 gtccataaac ctgagcacac tgctaggaat aggtcttgtc atatcatatc ctcctaaaag
     9301 atatatcatt tgatatcttt tttaattata agatataact ttatttttgt ctaccacttt
     9361 agaaaaggtt tacaagtctt ttttttcgtg atatactgct agagggagta aaaaatgact
     9421 gaattactat ataaaaagat atatcatttt atcaaggaac aaattgattc agggcaatta
     9481 caggcaggtg accgcctacc aacagaaaag gccctatcag agcaattttc ggtgagccgc
     9541 attacctcta agcgagcctt agtagagctg gagcaagagg gcttgattac acgcagcaga
     9601 ggtaagggca gctttgtgac cgatggccca ccaccgtcta ctcagcctaa taaggacatt
     9661 ttgttgatcc tgccctttgc ttctgattac gaattgggag attatgctaa aggaatcatg
     9721 acggtcgttg ctgacaaagg ctatcgcctg atggtccagc ttacaagtac ggtaagcttg
     9781 gaggagctag ctgattatgc tggtgtgatt tattatccag aagacgttaa tcatagtatt
     9841 gagctgctct tttattgtgc ccagcgtggg cttgctctgg tgcttttgga taaggcctta
     9901 gacctgtttg actttccagc agttgttgca gacaataagg gcggagccta tgagttgacc
     9961 aagcatttga ttgatcagga ttgccgtcgg atcatgtttg tggcaactgc ttcctttggt
    10021 gaggtttcct ctgttagaga tcgttatttg ggttatttgg ctgcgatggc ggaaacagag
    10081 cttgaggcca attattttgt gaagctgaag tcagaaagca atgctgctta tcttgagcga
    10141 ttggttgatg agctgacggc tgctacagct gaaaagactg gtttagtggt tgaaaatgat
    10201 tggctagcca ttcaattgat ccaaaaaatt ctacaggtcg ggctatctat tcctgatcag
    10261 gtagctgttg ttggctttga caacagccaa gcctctcagt taatcagccc tcaattgaca
    10321 acagctgcac aggattttta ccagatgggg cagcaagcag cgcaactatt gatagagcgg
    10381 ctgactcggc ctgatcagca gacggcgtct tgtcagcttc ctgttaaggt ctttatcaga
    10441 gaaagcagtc aaaagtccct agaaatgcta taaaaaggag aagtgtcatg tctatttatc
    10501 aagccctcaa ggactatcag gaggtgataa ccagaggtga ttacctcgtt tttgacgccc
    10561 ctgtttcctg tcgctttgtt ggtcgttttt tccgatttga gaaccaaaca gctatgaagc
    10621 ctagtcttac agcgtcagtc tatgtcaact gggttgagga gggagcagct gacttgaccc
    10681 ttaagcacgt ttttaaccgc accttagcta gggatgcctt taccttgacc atttcagagg
    10741 ataaggagct tgtgattgaa agccaaaatt taagaggctt tcgctatgct caggaggctt
    10801 tagaaaaggt aatgactgtt aaagagggca ggctttattt gccgattgtt tcggttaggc
    10861 atagtccgtc ctttgccatg cgtggtgtga ttgaaggctt ttatggcacc ccttggacgc
    10921 gtgaggagcg tttagattgc ttgagcttta ttgctgataa gggcatgaat acctacatgt
    10981 atgcccctaa aaatgatgac tatcagcgca gccactggcg tgagccctat ccagaggatt
    11041 gggtggctca ttttagggat ctgatccagc ttgccaagga aagacaggtt gacttttggt
    11101 acatgattag tccggggctt gattttgact acaccaagga agaggactat cagctgctct
    11161 atcaaaaatt gcagcaattg ttggatttgg gtgtttgtca ttttggcctg ctgcttgatg
    11221 atattgatta ccaaatagtg gcagcagttg agagacgttt caaaaaaaca gcctatgccc
    11281 aagcacattt ggcaacagct gtttaccagt ttttacagcg gcagcatgca gcccctgact
    11341 tggttgtctg tccgacagag tatgataatc atcatgactc tctttattta gcagagttat
    11401 cagaggctat tcctgctgag gtggcttttt tctggactgg cccaagcact ctggccagtc
    11461 agatttctca ggcagatatt gagacaatag cagccatcta ccggcggccc ataatcatct
    11521 gggataatat ccctgtcaat gattatcagg acgattctaa gaggctcttt ttgaccccgt
    11581 ttgccaatcg ctctcctttc ttgtgtcagc cagactatca ggtcaggggg attgtgtcta
    11641 atccaatgat tagctgggaa ctatcaaagc cgactttaat tgatatgagt cgctacctgt
    11701 gggacgccaa gcgttatcag ccaagctatt cttggctaga ggccttgaga gactatactg
    11761 gagataaggc tatggcttta gcgcttttgc gctttgcttg gcataatggc aatcgtcatt
    11821 tgcacaggga tctccccttt gaggtggagg aggcccttat gcgtaaggac atagctagct
    11881 tatctggttg ggtagctgag ctggtagagc tggtggataa gctgaaagag cttgatattc
    11941 ctgcgtttca acaggctatt gctccttggt ttgatcgggc taaggctgat cagagctttt
    12001 ggagggttat tttagagcaa gcgcctgatc ttgagcagca atatgctgag cttcaggagc
    12061 aaaggcatcg aattggaagc aatattccaa gccgctttta tcagttgcac tatcttcagg
    12121 agaatagcat gctaggcaat caggcacagg tcgctgaagc tagagctgag gattatactt
    12181 aattagttta taagggagaa caagggacat gctagagttt ccagaaggat tttggtgggg
    12241 aagtgctaca tcaggccctc aaagtgaagg ctgctttcaa aagccgcatc gcaatttatt
    12301 tgattattgg tatgagcaaa atcctgagct gttttatgat tatgttggac ctgatacggc
    12361 ttctgatttt tttcatcagt atgatcaaga cctagcttta ttagcgtctt tgggtcacaa
    12421 ttcctatcgg acctctatcc agtggacacg cttaattgat gattttgaga cagccacgat
    12481 caatcccgat ggactggctt actataacag ggtgattgat gcctgcctag cacatggtat
    12541 gcgtccggtg atcaatttgc accattttga tttgccaatt gctctttatc agaaatatgg
    12601 cggttgggaa tcaaagcatg ttgtggattt gtttgttgcc tttgctagag tatgctttga
    12661 gcagtttggc gatcgcgtta aggattggtt tgtacacaat gagcccatgg ttgtggtgga
    12721 gggctcatac ctgctgcaat tccactaccc tgccattgtt gatgggaaaa aagcggtaca
    12781 ggtggcttat aatctagcac ttgcaacggc taaggttatc tgtacctacc aagaacaagc
    12841 agcagagctg agcaatggca gtgttggtac cattctcaat ctgacaccga tctatccggc
    12901 aactgattca gaggctgatc ttgctgctgc tcatgttgca gagctgtggc acaatgacct
    12961 ctttatgtct gctgctgttt acggtagctt tccaaaggag ctggtagcaa tactacaaag
    13021 agatggagtg ctctggcagt ccacaccaga ggagctggat cttatggctg cttatacggt
    13081 tgattacgtg ggcattaatt tttaccgccc taagcgcgtg aaggcgccag aggttattcc
    13141 tgtgattagc ccttcctgga gtcctgagtg gtattatgat gcctatctga tgccgcagcg
    13201 tcgtatgaat gtggacaagg gctgggagat ttatccagag gcggtctatg atattgctct
    13261 aaaaatgcgt gatcagtata ggaatatccc ttggttttta tctgaaaatg gggttgggat
    13321 ttcaggagag gatcgttacc gagatgagag cggacagatt caagacgact atcgcattca
    13381 gtttttaaaa gagcacctga cctatcttca taaggggatt caagcgggct ctaattgctt
    13441 tggctatcat gtttggacac ctattaattg ctggtcttgg ctaaatgcct ataaaaaccg
    13501 ttatggtctg gtagaaaata atcaccgcac tcagcgtcgg cgtgtgaaaa aatcagggta
    13561 ttggtttaag gaggtggcag aggcaaatgg aattagctaa gaaaagaaga aaaacacaaa
    13621 agccagccca atctccttta aagctaggtt tagagaagct aagagagatt ttacaggagc
    13681 agctagtagc tttagcggtt ttacctgcta gggtgatggg ttagcataag ggcttgctga
    13741 tgagctatgc cagtgatagc gattaaggaa tgtaaaagag gatttcctaa catcataact
    13801 atccgtctaa cgggtgattt attgtttcgt acctacggag cgaaacggac taaagtcaca
    13861 taactaaaag catgtcatgg cttgctgtag tacgagtgat gacatgcttt ttttagcttt
    13921 taacgggtta gggagtaggg caggtcctca gccgaatagt gcttgagtgg gggaactagt
    13981 cccagctgaa agtcgagctg acagccctga atcagatcat catgattgat gtagagcttg
    14041 ttgtagctag cctgattgag cttgacctct ttgacaaatt ggtattgagg gacattgccc
    14101 ctacagctga tttggatagt attgccattt ggcagataaa gggttgcctg atctacagtt
    14161 ggaataccaa tcaggtattg cccagttcct ggtgtaacag ggtaaaggcc aaggctgttt
    14221 aacaggtacc acgcgctcat actgccattg tcctcatctc ctgggtagcc tgtatcggta
    14281 aaggcatgac tgagcagatt tttaaggatt agctgactgt attgtggctg accgatatag
    14341 tgatagagat aggggaggtg aaagcttggc tgatttgaga tagcaatctg accaaaatcc
    14401 tgtgcggcta gctcactcat ttcgtggatt tcaaagccat agctgtgaac gtcaaacaca
    14461 ggctcatgat tgcacagctc ctcaagtctt ttggcaatgg cggcgtttcc tccgatcagt
    14521 cgaatgtaac ctagaatatc atgataaaag gcaaatccat tttgataata ggagccctcg
    14581 gtgtagtcct gcccccagtg gatagggtta aagccacatt gccattgccc ttgtcgatcc
    14641 ttgcttttga ggtagccggt atcagtatcg accaaatggc ggtaattgag tgatcgcgtg
    14701 tggtattggt cactaagtgc tgtcttgccc agaagggcag ctacctggcc gatacaaaaa
    14761 tcactataag cataatcttg agtctgattg acgctttcct ggtagctatt tggcagatag
    14821 cctagctctt gatagtcttg attgcccttg cggccatagc ctgttccttg actgtctgta
    14881 ttggcagttg ccagcatagc ctctaaaagc tcaggcatca ggtcttttct gatgcctttg
    14941 acagctccat cagcaataac agcatcaacc aaggttccag gcatcaggcc tcgctcatct
    15001 ggagacagcc attttggcag atagttggtg tcctgataag ctgacaagag tccctctaaa
    15061 atatcagcat aaatctcagg tgcaattaga gacagcaaag gatagacaga tttataagta
    15121 tcccaaaagc cattgttggt atagtatttt ccagcaacag gtctttgact tgttgtatta
    15181 tagtgaatcg cctgcccggt tgcagtgatt tcataccatc tttggggaaa tagcagggct
    15241 cggtaaaaat gctggtagta ggccttgacc ttatcaaagt ctttatcctt aatgtcaata
    15301 cgactgaggt agctgagcca ctccttgcgg ctgtattcaa ggcttttttc aaatgatctg
    15361 gggaaatccc tctgccaatt gagctgagct tgatcaaagc taataaaaga agcagccgcc
    15421 ctaagctcaa gatgtttgag gtcatcagca aattggagat aggtaaagga cgtcttgctg
    15481 caatcatcaa gagatttgga gtttaagtct tctccgataa gcttttttag cacagggctg
    15541 ctaaactgaa gataaacaaa catggctagg tctttatcct gacagtctgt gatgttttgc
    15601 acacagccaa ggattgtttt accatcagct gtcacctgcc aggagctttt tccggggtta
    15661 tggataatca agcctgcttt gccattatca aaggaaaaat cacaatgaaa gctgtaggca
    15721 gctgctgttg ctcgcgtcaa aatccgatgt ctctggctaa aaatctcaag aagatgaggc
    15781 cgaaaagctg cctccttggg acgataggag gtctgattat gaaacacatc tcccttggtc
    15841 agcggtccgc tgactggaag aaaagtaacc gtcgcaaaat caccgaccca agggctgggt
    15901 tgatgtgtca agcgaatacc tgaaaagctg tgatcatcgg ggtgaaacca ccaagcccct
    15961 cgatcttgac tggtttcgac gcttagataa tgcatgccaa agggaacccc tgtcaatggc
    16021 aggcaatttc cctgtgaaaa atggtagtga ttggttgttc caaagcgggt gtcaatgaag
    16081 tctaatcgat ccacatctcg tcctttctat gctcttgcat aaaatcaata gaggcaccta
    16141 gtaggttggc ctcgttttta aagtggcaga tagcaagctg cggtctcaaa tcagaaatgc
    16201 tgactatctg atagagctta tccagttcag cctcaagggc aggaagaaga aagtcagcct
    16261 gagagacacc gccaccaatt aggatcattt caggatcaaa ggcatgctgg atattaaaca
    16321 cccccattgc cagactttga agaaagacct gtctttcctt tagggccaca ggatctcctt
    16381 gatcagctag ctctaagacc tctttaccgg tgtaactttt accatcattt atgatctgac
    16441 tatagcgctt ggccatattg accacagtgc ctaattcgct gaaggtttga taacgctcat
    16501 tcatgaccat aaagccaaac tcacctccaa ataaatgggc accgtaatga atcctgccat
    16561 taatcactag gctacctcca acaccggtgc caagtaccag catggcaagg ctgctagtgc
    16621 cttgtcctgc acctagagca gattcggcaa gagcagcaca gttggcatca ttttcaatcg
    16681 aaaccggcag acctagtcgc tcctcaaggc attgctgaat gggaaagcca tgaatataag
    16741 gcagtgcact tgctccctcg atgatacctg ttgctttatt gacagctcca ggggagctaa
    16801 tggcaattcc tgagagcttt tctgtgcggt agtaagccag tcgctcgtca agcatatggt
    16861 aaaagtcctc taggctttgg ggagttgggc gactgctttg cttttttagc ctgcccttgt
    16921 gacaaatagc aaatttgatg ctggtgccgc ctatgtcgat acataataag gtcattgtaa
    16981 ttcctcctat aacaggtata ttaccaatta gctaccctta gtatgacaga ttttgaagtg
    17041 cttgaaaaga ctttctcggc attcctatat tttgtgctat gatacctata atttgtgtta
    17101 tcaaacctat aatttgttgc ttgttctatg tgtaagcgct tgatatactt gaagcatcaa
    17161 ttgaaaagca aagggaggtt gggaagatga cgacaaagat cagcagcaag aaatcctttt
    17221 ggaaaaatgt gatcaaatac cgcgctttgt tgctgatggt attaccggga tttgtctggt
    17281 tcatcttttt cttttacatt ccagtattag ctaatgtagt ggcttttaag gattttcatt
    17341 actcagcagg aggttttatg gaaagcctga aagaaagtcc ctgggttggc ttagataact
    17401 ttaaatacct ttttgcctct aaggatgctt ggttgattac gcgaaatacc attgcttata
    17461 atcttatttt tttactattt aacgtctttt ttgccatcgc tttcgctatt atcatgagtg
    17521 agcttcgaaa caagaaggct gttaaggtct atcataccat gtccttactg ccttatttct
    17581 tatcatgggt tgtgattgag tattttgttt ctgccttttt aaatacggat aagggcttta
    17641 ttaatcagct gctcattgat agcggcaata gcccaatcaa atggtattcc aatcccacct
    17701 ggtggccctt gattttactt ttcatgagtg tttggaaagg acttggctac aacagtatca
    17761 tttattacgc atcggttaag ggaatatcag acacctacta tgaggcggct atggttgatg
    17821 gtgccagtaa gtggcagcaa attagacata tcaccattcc acagcttttg ccgatgatgt
    17881 ctatcctatt gattattaat attgggagta tcttcaaatc tgactttggc ttgttttatg
    17941 tgattcctaa aaattcaggt cctctttacg atgttaccag tgttttagat acctatgtct
    18001 acaatgccct gacagctact ggtgatatta gtatggcttc tgcggccagt ctttatcaat
    18061 ctgtggtcgg aacctgtatc ctgctcatca ccaatgcttt tgttcgtcgt atggatcccg
    18121 atgcagcctt attttaggag gaggacatgg agaaaaagaa aactgttaaa agggtcaacg
    18181 tcagaacctt tgacccaaaa accaatgctg tctttaatgt gttaatcgct ctttttgcca
    18241 tctcttgtat cattcctttt atctttgtga tgattatttc cttcacagat gaaagctatc
    18301 tgatcaatca tggctatagc tttttcccag ctgcttggtc gacaaaggct tatcattata
    18361 ttttccaagg ggctatgtct catcggatca taagatcgtt tgcggtgtct gtatttatca
    18421 ccgttttagg aacctttatc aataccacaa tgacctcaac ctatgcttat gccatctcaa
    18481 gaccttattt tccctacagg cgttttttta ccatctatgc cttgatcacc atgctttttg
    18541 caccgggtat ggtagccaat tatttggtgg tgagtaacct gctgcaatta aaggatacgg
    18601 tttgggcctt gattttaccg atggctctgg gaccctttgg cattttggtg atgaggacct
    18661 tctttaaaaa gaccgttcct gatagtatta ttgaatccgc tcgtatggac ggcgcaggtg
    18721 aattgatgat ttttatgaaa atcgttttac ctttggcagt tcctgggatt gcaaccatta
    18781 gcctgttctc agccttaacc tattggaatg attggttcaa tgcgctgctc tatgtgcaaa
    18841 gcgagagcct ttacccgatg caatacctct tgatgaagat tcaaagcaat atacaggcac
    18901 tagcccaaaa tgctggcatg agcgcccagc tatctgatag cttagcctct ttaccaaagg
    18961 aatctgtccg catggctatt gttgtcattg caactttgcc gatcgcccta acctatcctt
    19021 tctttcaaaa atactttgtt ggaggactaa ccatcggcgg ggttaaggaa taatcaccca
    19081 tttggaatag gtcatacagc tgaccgttcc aatgattctg ttatcaaaaa aagaaattat
    19141 tttaggaggc ttactgatga aaaagtggca aacaatctta tgtgtgacgg gagctgtgct
    19201 tgcagctgct agcttgacag cctgtggaag caaatcagct tctaaggacg gtgaggtgaa
    19261 gctattgatg tatcaggtgg gagataagcc tgataacttt gatgagctga tgacaattgc
    19321 aaataaacgt attaaggaaa aaacaggggc aacccttgat ttgcaataca ttggctgggg
    19381 tgattgggac gacaagatga ggatcattat tgcgtcaggt gaaaattacg acattgcctt
    19441 tgccaacaat tatgtggtca atgctcaaaa gggtgccttt gctgatttga ctaagctaat
    19501 gccaaaatac gccaagaaaa cctataagaa cctagatccg gcctacatta aaggaaatac
    19561 cattgacggt aagctttatg cctttccagt agatgctaac gtctatgctc agcaaatgct
    19621 gtctttcaac aaagaattgg tagacaaata tggccttgac atttcaaaca tcaattccta
    19681 tgcagatgct gaaaaggtct tgaaacaatt ccacgaaaaa gaacctaata ctgctgcctt
    19741 tgcgattggt caagtcttta gcatgtcagg tgactacgat tacccattga ccaaaaatca
    19801 accatttgct gttaaaatcg atgaaggcaa accaaccatc attaatcagt acgaagatga
    19861 gccctttaaa gcaaacctac gcttgatgca taaatggtat aaggaaggct tgattccaac
    19921 agatgcagca accaacacag aaggctaccc gcttgaaggc aatacctggt tcatgcgtga
    19981 agaaacccaa ggtcctatgg actatggcga taccatcttg accaatgctg ctggtaaaga
    20041 cattgtgtca cgaccattga caaagcctct taaaacgacc tcacaagccc aaatggctaa
    20101 ctttgtcgtg tcaaatgtgt ctaaaaataa agaaaaggcc gttgaagttc tttcccttct
    20161 taacagcgac ccagaattgc taaatggtct tgtttatggt gttgaaggca aggcctggga
    20221 aaaggttggc gacaagaaaa tcaagctgct tgatggctac caacccaaaa tgcacatggg
    20281 tgcttggaac actggtaaca acaagatcct ctacacccaa gaatcgatca cagatgatat
    20341 gattgcaaag cgtgaccaat caatcaaaga cgctaaagag tctccgatcc taggctttac
    20401 ggtagatacc aaggcaatca aaacggagct atcaaaaatc tcaaacgtga tgaaccgtta
    20461 taaagctagt atcaatactg gtacagtaga ccctgatgaa gctcttccaa aacttctttc
    20521 agaccttaag gacgctggtt gggacaaggt tcaaaaggaa gtgcaaaagc aattggacga
    20581 ctttgttaca aaaaataaat aaggcaatgg actttccttg caaggtggta agaactgggg
    20641 acagcctcag ttctttttag ctcaagcagg catacaagag ctgacagata aggcctctct
    20701 tagaaaaaag ccagagcctg cttgcaaggc agttggtcca ccaaagccct tgctgacaag
    20761 gttttaccag ccttagtcgg ctgtcctctt tttattaagc ttttgtcaca attagagtaa
    20821 aatatgctat attagaagta tctcatctta tcatcatgac agctaagacc ttagtcatct
    20881 ggctgaggga tcgttgcttc tcttagggcg ctattggtcc tacaaaggat actagaaaag
    20941 gataatctta tgacaggaat tgaaaaagcc tgctttctca tctggaaaat gatgcagcta
    21001 acccttatat ttcatttgct ttccttatgt ggtgctgtga tttttggagt ggggccagct
    21061 tggcagacca ttgttacctt gtttttggag accagtcagc aggagaaaca ttattcgctc
    21121 aagcgggcct ttcagatatg gcgtcgggtc ttcaaagagg ccaatctcag ctttttcttc
    21181 tttggattat tgctattatt gctgaatacg agcctgtact tggccattca atttcaatcg
    21241 ctgctgtggt ttagcctatc ctttattatc atgtttgtca tggtttggct ggtgatgatt
    21301 gtgatttaca tgacctttta tgcagtgacc tatgaaattg ctttttggga gaatctcaag
    21361 ctgtctttta tcagtatttt cttgaatgcc aggcagtttt tgttgaccct tgtggtttta
    21421 gctggagttg cttggtttac ttggcagtat aagggcttgt atctttttct gagctttggt
    21481 gcgctggttt tgttgctgga tatggtcacc aagcctaatc gtcgcatggt agatggagtc
    21541 attgatgaca agtaaatctt taaagcggtt cttgatggag catattaagc agggcttttt
    21601 aattaaccgc ttgatgaaaa tatatagcct gtttatcgtg gctctcttta gcttaagtgc
    21661 ggttggtcta agcacctatt cgattcgaaa tacctaccaa atggttgaca atcaaatgca
    21721 aatgcggcta gatgagaccc tagcaaggct acaatctcaa aactatatta ccctgcgcgt
    21781 gctggagcag ctgatcgggc gtccagagga ttatcgaaat ctgtatcagt acatgatatt
    21841 gacccctaat caatatctta ctaaggtttt tgaggattgg ggtgagggca aaaacacacc
    21901 tctgttttca gagcaggtca gaaggctttt tgatttgtat ccagatttag atgggctgac
    21961 cctgatgctg gacgatagca cgtcctattt gtatgcagat aggtcgatta agaccggccg
    22021 gctcttattt ggtaagcctc agacgctaaa gggcaattac ttagtaaggt ccattcgcca
    22081 ccctgagtca ggtgatgtta caggccgcct ctatctgcac tttgcaagcc ccagcacgat
    22141 gctacagcct gagcagcata agtatctagc gacctttgcc tttgattact atggcagaga
    22201 gctctttcat cagggaggcg ctgcctttcc ggagcttgaa gcaggtctta aaaaggcgct
    22261 aaaggcggat caggctattg atttgacagc tctcagcaag agctatcata ttcagtacaa
    22321 tcgctcggga gacttgctgg cctatgtggc ggtcaaaagg tcttatttta tggaagaggc
    22381 tgtgcgtaca atgctcctgt atggccttgg ctcgttattg ctagcttggt tattgctaca
    22441 gctccttttc agggtatttc gcaattatat ccgacaggtc tctgagatta cagatactat
    22501 tgaaatggtt gcagctggtg atttgtcgtt aaggattgac aacagtcata tggaattaga
    22561 gctgtatcac atttctgagg cgatcaatca aatgcttggc aacatcaatg cctacatttt
    22621 agaaatctat gtccttgagg ttgagcaaag agatgcccag atgcgtgcct tgtcatcaca
    22681 aatcaatcct cattttttgt ataacaccct agaatatatt cgcatgtatg cgcttagctg
    22741 tcagcaggag gaattggcag atgtgattta tgcctttgcc gctttacttc gaaataacat
    22801 cagccaggat aaggtaacca ctctaaaaga agagctggct ttttgtgaaa agtacatcta
    22861 tctgtatcaa atgcgctatc cagatagctt tgcctaccat gtcaagcttg atcctgtcgt
    22921 ggctgatgtg gaaattccta agtttatcat tcagcccttg gtggaaaatt attttgtgca
    22981 tgggattgat tacagccgct atgataacgc ccttagcatc aaggcgctag atgaggagga
    23041 cagtattttg attcaggtgc ttgataatgg caagggtatt agccctgagc gcttagtggc
    23101 tattgaaaag ggcttagagg agccgcaatc gacggggaat agctctattg ggctgcaaaa
    23161 tgtctatatg cgcctatttc acaaatatcg agacagagtg acttggtcca tgtctcaggc
    23221 accgactggt ggctttagga ttcagatcag aattagaaag gaagcttaat gtacaaggtc
    23281 ttattagttg atgacgaata catgatttta cagggcctaa aggtgattat tgactggcag
    23341 gcgcttggct ttgaggttgt ggcaacggca aggtcagcca aagaagcctt agcttaccta
    23401 gatgactgcg ctgtagatgt catgatttca gatgtcaata tgcctggtat gacaggcctg
    23461 gaattgattg aggcagcaag agatgtattg ccgcatttgc agaccttgat tttatcaggc
    23521 tatcaggaat tttcctatgt gcaaagggct atggagctag agactaaggg ctacctccta
    23581 aagccagttg ataaaaaaga gctggtagct aaaatgctct attttaagga atggcttgat
    23641 gagcagaggg cagcttcttt gcgtcaggct gcttatcgtg agggcttgat aaatctctgg
    23701 cttgctgatg aattgagtga gaaagagttt tttcaactaa cgcaggagca acccgaggct
    23761 gagcttttag gctttacggt gttgtatgtg gattgcaaga cttttagccc tgccttagaa
    23821 gccttttttg aggcctccaa gcagcccttt tacttaaaaa aggcagagca aaagaaggtc
    23881 tatctagtca ttctattagg acagagccat caggctaagc gctttactaa tacgcttcag
    23941 gagcgatttt acaataccat caatcagatc attctaggag aaacggttgt tgattgggaa
    24001 aatgtgtatg aaagctataa tcaggtcaga aggagctttt tttacaacag cgaggtgtct
    24061 caggtagctg ctaagaccaa cgctaaaatt gagctgccgg aatcgcgatt gcagtttttt
    24121 tcctttaaca agaccttgat gattggggac gagccaacta ttgtctccaa attacaggca
    24181 atctttgagg agatgacaga gctaagcttc tctcctgagg acgtcaagca cgtctctttt
    24241 ctcttatttt cagacattta tcgccaattt ccgattttag atcgaacgac ctacctatcg
    24301 atggtcaaga ctattcacga tagtcagtcc attgatcaga tcttatcagc cttaaaaaag
    24361 gtgcttgagc tgacaagcaa aagcaatcag ccccaaaagc gctattctga tctggtcagt
    24421 gaagccatta cctgtattca ggaggaatac tctcaggaat taaccctcaa ggctgtgtca
    24481 gatcgcttgc atatcaatgg ggtttatttg ggacaacgct ttaaaaatga aacagagtgt
    24541 agtttttccc aatacctcaa tcaggtgagg atccaaaagg cacagcaatt gctgctttac
    24601 accaataaat cgattaacga aattgcctat gagacaggct ataatactaa ccattatttc
    24661 ataaaaatgt tcaaaaaatt aaatggttta tcgcccaagg agtttagaga ccgttataaa
    24721 gataattatc aagctataaa aggaagctat taagaaaggg ggcgctatgt ctgtagagac
    24781 aatcactggt tcaacggatc aatctcatgg ggatatctat cagcttcact ggattgataa
    24841 agtagggcgc tgccatgcct tttcaaaggg gtggcgcttt ctgatggctg atttgcagct
    24901 cgctcaggag ccattttttg atgattcgga ctggcagcag atagctttac cacatgattt
    24961 tagcattaat cagccctata cggttaatgg cgaagctcaa agtgcctata agctaggtgg
    25021 tgtaggctgg taccggaagt attttgccct tgatccaaag ctggctgacc ataaggtcta
    25081 tgtgaccttt gatggggctt atatggaaac gcaggtatac cttaatgggc atttgatagg
    25141 agagcatgtc aatggctatc aggcctttag ctatgatctc tcagcctttg taatccctgg
    25201 gcaagagaat ctattagcgg ttcgggttga acatctggtg cctagctcgc gttggtattc
    25261 tggaagtggg ctttatcggg aggctttttt gaccgttctt ccgaaggttc atcttgataa
    25321 ggatcggctt cgtttatcct tatcccaggc agcgcttgag gctgatagcc aagcgcttga
    25381 gatagagctt ggactcagcc aacaggtccc cttgagtggc tatcagctta gccttagtct
    25441 gtttgagcag ctggcagata tccagcagag acagacagta tatgagagta aaccggtagc
    25501 cttggacctc ttggaggagt caggtaggct ggtgatgacc attcctctta ggcatatcaa
    25561 actgtggtcg ccagctcagc cccagctcta tcagcttgat atgcttcttt accataaggg
    25621 agcagtgctt gatcggctga cacttgaaac aggctttcga cagctgcatt ttgatgctga
    25681 gtgtggtttc tttttgaatg gcaaagcctt taagctgcaa ggggtctgtc ttcatcatga
    25741 tcagggtagc ctgggggcat gtgcttatga ggaagctata gctaggcagc ttgttttgct
    25801 aaaggaaatg ggagcaaata cggttcgtgt cacgcacaac cctagtgcca gaaggcttaa
    25861 ggatctggct aacaggcttg ggttatttct cattgaggaa gcctttgata cctggactta
    25921 tgctaaaaac ggtaatagcc atgatttttc aagccatttt cacaagacag tgggacacca
    25981 aaatgcagcc aggctaaagg gagtcactac agcagaaacc acctgggcgc aatatagcat
    26041 acaggccatg gttctctcag gtcttcatga tccatctgtc ttgatgtggt caatcggcaa
    26101 tgaattgtta gaaggcttct cagctgatgt gagccactac ccttatgttg ctaaggagct
    26161 atgccagtgg atcactgagc tggatcagtc aagacctatt acccttgggg ataataagct
    26221 caaggacaag cattttcatt gggcgcagga aacaaaagcg ttggcagagc aggtcaatca
    26281 gctccagtcc gtgcaaggag tgattggact taactatgct aaggccagag attatgatcg
    26341 attgcatagg gacaacccga cttggctgct ttatggctca gagacagcct ctgctattaa
    26401 tagtagaggg gtctatcatc tcaagggagg agctagtcag gatcatgagc taacctccta
    26461 tgaccagtca acggttgact ggggatcctt agctagtgag gcttggtatg atacaatcac
    26521 aagggatttt gttgcaggtg agtgtgtttg gacgggcttt gattatctag gggagcctac
    26581 tccttggaac aagattgact caggcgcagc tgatcagtgg ccgtcgccca agcaatccta
    26641 ctttggtatt ttagatactg ctggatttgc taaggatagc tattatttct accaaagcca
    26701 atggtcaaaa gacaaaacga cacttcatat cctgcccagc tggcaggaaa aagaccttca
    26761 gctagatgat cagggcatgg tggaggttgt ggtttatagt aatgctgcta gtgtgagaat
    26821 actttttgat gatggtcatg ggggccagat tgattatggc atcaagaccc tgacaaggca
    26881 tgaaacacca gcaggccatt gctaccagct atatgagggt gacgatgcag cagaattacc
    26941 tcatcaaaac ctttacctga catggaagct tccttatcgc tcaggcagct tgagagctat
    27001 tgcttatgac gacaagggac aggtgctcac acagaccagc ggtcgttcct gtgtgagcag
    27061 ctaccagcag cctgctcagc tttcctggtc ctgctttgag cctcctaaac tgcttgcaga
    27121 gcctgcgcta ctttatcttg aattgtcttt gttagatgct aatgagacct tggtgctcag
    27181 tgctaatcct gtgattaagc ttgaggttga gggtcctgga gcctgccttg ctctggataa
    27241 tggcgatcct cgtgaccata ggccctatac tgccttgtca cgccgagcat atggtggcaa
    27301 gctattagcc attattgctc ttgatggtcg tgcgggtcag cttagaataa cagctagagc
    27361 cgcaggattc gtggaagcca gctatcagtt gacggtttct gaagcagccg ttaatgagaa
    27421 gcttttagcc tatcagcttg ataaatacag ctttatcact aatgagacaa ataagcctag
    27481 caagccctat gcaaggtcaa gaggatcagc tgttgatagc ttaatgccta atcctgatag
    27541 ctgcttaaag cggcaaggcc attatctgcc tgataattct gtaatggttt ttagctatac
    27601 aacagcatta tcaaggccac tgacctttca gccactgatc aaaaggctgc taaagggcaa
    27661 tgatatcatt ctaccagact ggctgcagcc tagggcagct gctggccagt tatttaccaa
    27721 ggcttttcct attgattggc agctaacaga ggcagttttt tctgaggagt caagggttag
    27781 tgggcagacc ctttgttttg gagaggcttt ggagcttgaa gctatcctta agtcagatac
    27841 aaaaggatta aggatcaatc aagagcttag cttagttgct aaaaagaagc ggctgtttca
    27901 gagtgatacc cagcttagct accgctatca atacgatacc atacaggcca ttggtgccat
    27961 tagcctgaca ggactaaaga agcccttaag ctcgcttagg cttgttttgg actatcgcag
    28021 cagcaccaat gcgccatcaa aacagctgat cctatcgctt gatcagatag aacagccctg
    28081 tcactacatc atgctggaag aagtagttga tgtgctaagc ctggacctaa cattagagca
    28141 gccgatcaga caggcttttg acttagctag gcttcagcta ggcctttgga gcatggttga
    28201 ggaggcttag gcttcaagct tatcggctca tactgtcaat aggattgagc tgagacagtc
    28261 tttgaaaaat aaggtataat gacagtaaat gcctagcaag ctttgctagg ttagcaaaaa
    28321 ataagcatcg cctgatatga tgtaaaggag gaggtatttg atgctagagc gtttatcagg
    28381 tcagacacga ttaacagctt tgctggcagc accggcacgt cacagcctat caccgaaaat
    28441 gcacaatgca gcttatgcta agctggggct ggattatgcc tacctagcct ttgaggttgg
    28501 taatgctgag ctagctgctg ctgttcaggg catgcgtgcc ttgggtattt gcggtgcaaa
    28561 tgtgtccatg ccaaataagc aggccattgt cccattgctt gatgagctat caccggctgc
    28621 agccttagct ggagctgtta atacggttgt taataaagat ggcagaggtc atcttgttgg
    28681 tcatatcacc gatggcacag gtgctattcg agccttagca gaagaagggg tctcgataaa
    28741 ggatcagatc attacgattg ccggtgcagg cggtgcaggc acagccattg ctgttcaact
    28801 gggacttgat ggcgccaagg agattcgact atttaatcgg aaaacagcta cctttaagca
    28861 ggccaagcag ctggttgcta gaattaatac ccaaacctca gccctggcaa gccttcagga
    28921 tttagcggat gatcgagcct ttaggcggtc tatttcagag tctagcattt atattgacgc
    28981 gactggtgta ggcatgaagc cttttgagga gcatcgcctg attactgatc cagctcttat
    29041 tcgcccagat cttgtggttt ttgaccttgt ttatcacccg gcagaaacaa agctcttagc
    29101 ctttgcgcgt gagcatgggg ctaaaaaagt gatgaatggc ctaggcatgc tcctttacca
    29161 aggagcagaa gcctttaagc tgatgacagg tgaagacatg ccggtagcct atatccgaga
    29221 gcttttatgt cagaacaagg aatgaacgcc tgctgctcac gccggtatag gaaaaagaaa
    29281 aaaaggttaa ttgctcagct ctttgattgg tcttgaggtt tgtcggcatt ttatttataa
    29341 taaaaagcac caaaagcaaa ggagcagcct atgatattga cacaatttga ccctgactac
    29401 caagctatca ttaaccctaa ggaccttgta gcagaaatag atgactttcc taaaacagta
    29461 gtcacctgct ttgcaagagc aacctttaat agggtactta atgcactgcc acatcgactg
    29521 atagccacaa caagcgttgc taatcttgat attccaatat acgaattaga tgttaaaggg
    29581 cataagcttg gctttttcaa ttcctacgtt ggagcagctg gctgcgttgg ggttttagag
    29641 gatatcattg ctatgggaat gaagcagctc ttggtttttg ggacctgtgg agtcttagac
    29701 gctactatca gtgaaaactc tattattatt ccaactagtg ctattcgaga cgaagggacc
    29761 agctaccact atcagcctgc tagtcatgac attgcagtga atcaagctta tttaacaagg
    29821 gctattgatg ttttagaaca gcattcccag acctataccc ttggtaagac ctggacaaca
    29881 gatggcattt atagagaaac cagagacaag atgattcaac gaaagcagga aggggctatt
    29941 tgtgttgaca tggaatgctc tgcgattgct gccctagcag ctttcagaca gctagagcat
    30001 tttcagtttt tttattccgc tgataatcta gatgctgatg aatgggacgc aagaagctta
    30061 gccaatgaag cagacctaga agccaaggat aacattgcct ttattgcctt agagttggcc
    30121 ttacgattat ttaaggataa ttaaaaaagc accaagagct atgaagtgcc tccaaaaggt
    30181 tagattaagg ctctaacgcc tgggagatca gttcagctca aggtgctttt taggtgtcat
    30241 gcagacagct cacctctgca tgtcaatata atgtttagag tagcctatgc ttcttatacc
    30301 tatgccttag cattcaccta gggacaaagc aatgaagctt aggcctttca ccttactgtg
    30361 aaaaaagtgg tcttttctca tcaaaagact cagtaaacaa gaggctttga agcctttttg
    30421 tttttcagaa gcagcagttt tttcactcga ctaataagac aggagaaaag ccttctcagg
    30481 cgatatctag caggcttctt agccaatcca gcaggcgact gtcatgctta gcaataggaa
    30541 agcttacata gccttttgtc gttggcaaaa tgaggacaat atgctgacca gaatttttct
    30601 tatctgtttt taaaacagtc atcaaggctt cggctgtcat tgacttagcc tcaagtgtgg
    30661 taggtagctg ataagcctca aaggcagcct gtaatgcctc taaatcctgt tggctcaata
    30721 gctgctgctg gacggccagc ttggcctcaa agaccatgcc aatcgcaata gcctcaccat
    30781 gcctgtaaag ctcgtgatgg cataaggctt caatcgcatg ccctagcgta tgcccgaaat
    30841 ttaaggacat gcggagattg ccttcaaatt catccttttc aaccactctt tttttatggc
    30901 aaatcgcttg aaaaatcatt tgcctgagct gctcttgatt gcggtccttg gggaaggcta
    30961 ggagctgttg aaagagcttg cgatcatgaa taaaaccaat tttaatcatt tcgctgatgc
    31021 cgcaggcaaa ttctctttca gaaagcgtgt ctaaaaactt ggctgacacg ataatctggt
    31081 ttggagggta gatactgcct atcatattgg tcaagccctt aaagtgaacc ccaaccttac
    31141 caccaatgct gctgtctacc tgactaagta aggttgttgg aatctgaacg taggaaatcc
    31201 cgcggtaaaa ggttgccgca acaaatcccc caagatctcc aatcacccct cctccaacag
    31261 taacaatgac gtccttttta gaaaaattag ccctaatcag tcgatcgtaa atccgactaa
    31321 cctcctctag agacttagat tgcccccctg gagcagcaat atgaaggtaa ctatcgtaat
    31381 cctgttgaaa acgtctaaat aaaggctggt ataaatcaaa taccgtttga tcagtgataa
    31441 ataatagctt gacgtctcct ttttcagcaa gaaattgatt cagcggctga aaaatatcgt
    31501 ctgtaaagat aatcggatag tcattgatac gagacttaac ctgaagtgtt tgtgtcatgc
    31561 gtctttctct cctaagcacc attagttcaa atgactggac ctgtggctgc tgttagttag
    31621 ctttcccaaa gctcttttcc aagctgctct agctgttgat aatcaatctg ctgcgcggca
    31681 tctgacaagg caagatcagg tgtagggtgc acctccatca taataccatt ggcaccgata
    31741 gccttagcgg ccttagccgc aggcaatagt aaatctcttc ttcctgttga gtgagagaca
    31801 tcaacaatga ttggcagctt caccttttgc tgaataatag ggactgccat gatgtctagc
    31861 atatttctag tttccacatc atagccacga accccacgct cgcataaaat aatattttgc
    31921 ttgccatttt cttgtaaata agataaagca cccaaatatt cctcaatggt tgccattagt
    31981 cctcgtttaa acaagatagg cttgtcaatc tttgacaata cctttaacag ttcaaaattt
    32041 tgcatatttc gagcgccaat ctgaataata tctaaatagt cataggcttc ctctagctgc
    32101 ctttcagaca taatctcact aacagccttc agcgaaaatt cctggcaaac ctcatgtaga
    32161 taggtaaccc ctgtcagccc taagccctga aaggagttag aagaggttct aggcttatag
    32221 gctccccctc gaaaatacct gtagcctaaa gccttggcac ttgctgctgc ctgtctgatt
    32281 tgctgataag attcaatggc acagggacca acaataaagt tactcttttg acagcccttg
    32341 tttaaaaaat cagctattat atcgtttccc atttatactc tttcctaata tgatattgag
    32401 agaatgattc cccaaaggta agatgacagc tctgtcttag ataatactgt gaataaggca
    32461 tgacagaact attcatagct tgggaaatca taccataatc aagcttaaat ttcaagctaa
    32521 taaagagagt gaccagctcg ttgacaaagg agaagctttt gagaatccta gccctctaag
    32581 gtagagattt tatggctatt agagctgttg agaatgctta ttagctggaa taggcaagca
    32641 tggtggggaa gtgctgatga ttgagtatca tgatgaggct agttatagct tttattgtgg
    32701 gagagtttag cttttcaaat acaaaaagaa aaggtttacc tatatcgttt ttttggtgta
    32761 tatataatat atagaaagca aactatttta gaaacagagg taatggtaga tgttaaggta
    32821 tttaaaagcg attttatatc tattggctcc cagattagct ttttcagtaa caggtgtatt
    32881 atttcctgat gtttttgata atttattctt ggtttataat attttaatga cacttgcttt
    32941 ttggcttgcg atttattctg ttgacctccc agaaaaatag ttgcgggact tgtttagtag
    33001 ttggttaaca aagggtagat gatcagttaa aggtgaagcg tctgagctat gttggccatt
    33061 atgcgtacag ctggcaaaat gcttttgatc caatcggtta aacctcaagc tattctcttt
    33121 gggataacaa ataccccatc tgtctcagac aaagaatggc aacgcctaaa taggattaac
    33181 atctgcaagt gctcttggga ctgccaatgc tcttagtagc ataggtgatt tttcagcgct
    33241 agagactttt cagcagatga gaaatagtcg caataaacga agacaaaaag acttggcttg
    33301 agctcgtatt tggccttaaa atagtagtca gtcgagctta aaaaaaagtc attgcagctt
    33361 atgaaggtta tcgtatcctt atttcaactg agctaggtaa gctagggagt ttcctttagg
    33421 tgtaacgata gaagcgatca aataattact tcatttaaag ataaggattg taataagcat
    33481 agaaaagagc agttacttga cataactact caatgtaaaa ccgtttcagg cggtggcttt
    33541 tgttattaga taaaaaataa tcgtcatcat tcggccaaag ttagaacggt tatgttttat
    33601 gctcatcttt gaagatgtta tagcacaagc caatagggag actaaagctt aaaaagagtt
    33661 tgagtagctt caaaggctgc tagctttttg gcctcctcca ttttgttagc tgttgatgaa
    33721 tcgcccatag gcaccaccac ccactcagaa cgagcagcca cctgtcttaa tttttttact
    33781 ctaccactgt agcatgccac aagaaaaaat cagaacacta atgacattta aaaaaaaaaa
    33841 aaaaaagact tgcacaccaa aacaagttat agtatcatag aaaggtagcc gctatagtta
    33901 aatggtataa taaagcaatg gtaatgcttc gttccgagtt cgattctcgg tggtggcatc
    33961 tgagtactgt cctaagtctt attaggacgg tttttttatt gctaggtgaa ccaatagtag
    34021 tcatctgtga atcattacca tagtggcttc tgttcgccca agcatagcaa agctgctgtc
    34081 agaatgaacc cagccaacaa tgtcaataga agcagcacca gacaagcctt tagtcaccca
    34141 tgctttaaag attttacggc tgtaatgtta gtaactgtta cctgttttgt tcaagttgtc
    34201 tgtgacatca aatcacttga tgctaccagt actgtcaata cattagctgt cacttggcag
    34261 ttgttctgac tactactaaa aatagcagct atcagcgttg caatcaaaaa agaatgcgaa
    34321 tcaagctctc ctgatcagct taactttttg aaagagtttg tacgggtcaa gcatcagcaa
    34381 gtcagactgc cttatttgtt tttatcataa gcttctaaga aaatagcaca ataagccagg
    34441 ctgtggtata atggtaagga ttaagtcaga aagagggggg cagacatgtc ttatgagcaa
    34501 gactttttga gagattttga agactgggtg aaggctcaaa ttcaggtcaa ccagctagct
    34561 atggcaacga gccggcaaat tgcaaaggaa gataatgatc aaagagccag agatgccttt
    34621 attcgttatg agagtaagct agatgcttat gagtttttat taggaaaatt tgataattat
    34681 aataaaggta aagcttttca tgaggtgcca gacagcctat ttggtagccg tcattattag
    34741 aggaagggat aagcagtaat catggcaaga cgatacaatc gtaaaaaaca atacaagcta
    34801 cagcttaagc gtcaaggact gctcaaggca gtaatcaatc aagtggagca gactgtggaa
    34861 aaggtggttg ataagactaa agaagcagtg cataccgctt cacaaatggt aacagcatca
    34921 aagacagaga ctgctgatct acaggataag cagagcattg ctgaaaaagc agctcagcct
    34981 aaagcagatg tagcttctag tagcttggct gacagttctg aggtttcaag tgaaaaagag
    35041 gcctcaaagg ctagcagtga agtcttatca cgcgatgctt ttgcagagtt ggctgaggtt
    35101 tcagagcttc gggcagatat tgttacggtg ctttttgagg ctggtattag gtcagctgct
    35161 gcttttagcc aatggacaga ggcagagctt ttggcgctta agggaattgg accagcgact
    35221 atcagcaagc taaaggaaaa tggtgtcaac tttaaaaagt agtctgattt ttattgctta
    35281 ataagtataa atttgttaga atgttagcaa tcagaggtat cttgagtttg tctgttacag
    35341 agagcggtgg tgttgagaaa tccgcacaga tgtcaagtta tgtagctgag gcttacaatg
    35401 gaaaaatgat aaagcagcag attaagtgta atctgaaaca gtggtggtac cgcggattat
    35461 tagtgaattc gtccctgtct agtcgattga ctaggcgggg ttattttttg gaggacttgc
    35521 tatgattgag ataatgggtt ctgttgagaa taatagatta ccagatgtca aaactagtcg
    35581 tttgctgctg cggcagcgta ctttagctga tgttgaagcg atttttgctt atgctagccg
    35641 acctgaggtt agttacccag caggctttcc acctgtgaaa acccttgaag aagaggagca
    35701 ttacatcgca aacacgatgc ctaagcgctg gcttttgcaa cagctgccgg caggctatgg
    35761 cattgcccta aagggtgaca ataggattat tgggtctgtt gattttaaca accgtcacgc
    35821 agatgatgtc tttgaaatgg gctatctgct ccaccctgat tattggcatc aggggattat
    35881 gactgaggca gcgagtgccc tgctagaggt tgcctttact ctgcttaagc ttcataaggt
    35941 tgaaatcagc tgttacgatt acaatatggg gagtcgtcgg atcgcagaaa agctagactt
    36001 cactcttgag gcgaccattc gtgatcgcaa ggacgctaaa ggcaatcgct gcgcagactt
    36061 gcgctatgga ctgttgaaaa gagaatggga gaggcagtgt agataaggag tagactctct
    36121 aaaatatgcg ttaatctgtc aaaagcattt cataagaagt cctcaaactc aaagcgctta
    36181 tgactaccaa aactggttag cgcttcgcca accagtgtca tcagtttctg gtagtctgcc
    36241 ttgagcagca agtgttatgt taagtgaggt gagaagaggt aagagagatc ggaaagaggt
    36301 ttggtatgaa tattatctta attggagcac aggcgtctgg taagatgaca attggacagg
    36361 aattagaaaa actgactgac ctgactttat ttcataatca tgaatcgatt gattttgtga
    36421 ctaagtttat accaatgtca tcggaagcta gagaactaat tgatgagcta cgattgctat
    36481 tttttaaaac atttgcaaaa cgtcagcaat caattatttt tactgttgtc attgatttta
    36541 atgcacctga agatatagcg tttttggaaa cactacagag tgtgtttcat gatttcgaca
    36601 gagaggtttt attcgttgaa ttagaaatag atttaaaaga acgcttaagg cgaaataaaa
    36661 ctgaaaatcg actttaccac aaaccgataa agcgtcattt ggagtggtct gagaaagata
    36721 ttttggatac tgctaaattt gctaacttta accctgcaaa ggtaccagaa aatcttaaat
    36781 attattgtaa aatcaataat acgagtcttt ctgctcaaga aacagcgcag tttatcgtcc
    36841 aaaaaatgaa agagttagaa gtaagctaga aaggacacca tatgtcaaaa gaactttcac
    36901 ccaaatacaa tccagctgag gttgaggctg ggcgttatca agcttggctg gaccaagatg
    36961 ttttcaagcc atcaggcgac aagaaggcta agccgtatgc tatcgtgatt ccaccgccaa
    37021 acgttacagg gaagctgcac cttggtcatg cttgggacac gacccttcaa gatattatta
    37081 ttcgtcaaaa gcgcatgcag ggctttgata ctctctggtt gcctggtatg gatcatgcag
    37141 gtatcgccac tcaggctaag gtcgaggagc gcttgcgcga gcaggggatt tcccgttacg
    37201 atctcggtcg tgacaagttc ttagacaagg tttgggaatg gaaggacgag tatgcagcaa
    37261 ccatcaagga gcagtggggt aagcttgggc tttcactaga ctatgcgcga gatcgcttca
    37321 ctcttgatga ggggctctca aaggctgttc gcaaggtttt tgttgagctt tacaagaaag
    37381 gctggattta ccgcggtgag ttcatcatca actgggactc ggcagctagg acagctcttt
    37441 cagatatcga ggttatccat aaggacgttg agggtgcctt ctaccacatg aactatatgc
    37501 tagaagatgg ttcgcgcgcc cttcaagtag caaccacacg tcctgaaacc atgtttggag
    37561 atgtggctgt cgctgtcaat ccagaagatc ctcgttacaa ggacttgatt ggtcaacatg
    37621 ttgttctgcc aatcgtgaat aagctgatcc caatcgttgg agacgagcat gcggatccgg
    37681 cattcggaac aggggttgtt aaaatcacac cagcccatga cccgaacgac tttgaggttg
    37741 gtgggcgtca taatctccca caggttaatg tcatgaatga tgatggtacc atgaatgagc
    37801 ttgcaggtga atttgcaggt atggatcgat ttgaagctcg taaggctgtt gtggctaagc
    37861 tagaagaaat cggtgccctt gttgagattg aaaagcgtgt tcattcagta ggtcattcag
    37921 agcgtacagg tgttgtggtt gagcctcgct tgtcaacaca gtggttcgtg aagatggacc
    37981 aattggctaa aaatgctatt gccaaccaag acacagatga caaggttgac ttctacccac
    38041 cacgcttcaa cgataccttc ttgcaatgga tggaaaatgt ccacgactgg gtaatctctc
    38101 gtcagctttg gtggggacat cagatccctg catggtacaa cgaagcaggt gacatgtatg
    38161 ttggtgagga agcgccagca ggtgatggct ggaagcagga cgaggatgtc cttgacacct
    38221 ggttcagctc tgcgctttgg ccattttcaa ctatgggctg gcctgatgta gactcagaag
    38281 atttccaacg ttacttccca acgtcaacat tggtaacagg ttacgacatc atcttcttct
    38341 gggtgtctcg tatgattttc caatcgcttg aatttactgg gcgtaagcct ttctctaacg
    38401 ttcttattca tggtctgatt cgtgacgaag agggacgcaa gatgtctaag tcgcttggaa
    38461 atggcattga tccaatggac gttatcgaaa aatatggtgc agatagccta cgctggttcc
    38521 tatcaaatgg ctcagcccct ggtcaggacg tgcgcttctc ctatgaaaaa atggatgcgt
    38581 cctggaattt cattaacaag atttggaaca tttcacgtta cattctcatg aataatgagg
    38641 gcttgacact tgagcaagca agtgcaaatg ttgagcaagt tgcgtctggc gctgctggaa
    38701 acgtgacaga ctgttggatc ctccacaatc tcaatgaaac aatcggtaag gtcacagaga
    38761 actttgataa gtttgagttc ggtgtggcag gtcatatcct ctacaatttt atctgggaag
    38821 aatttgccaa ctggtatgtg gagctgacca aggaggttct gtacagcgac aacgaagacg
    38881 agaaggttat cactcgctct gttctcctct acacgctgga taaaatcctg cgtctccttc
    38941 acccaatcat gccgtttgtg acggaagaaa tctttggtca atacgctgaa ggttctatcg
    39001 tgacagcgga ctatccaacg gttgatcctg cttttgaaaa tgaagctgcg cacaaaggcg
    39061 tggaaagttt gaaggacttg attcgtacgg tgcgaaatgc gcgtgcggag gttaatgtag
    39121 caccaagtaa accaatcact atccttgtca aaacaagcga tagcgacctg gaagccttct
    39181 tcaacagcaa tgtcaactac atcaaacgct tcacaaatcc agagaggctt aagattgctt
    39241 caagcattgt gactcctgag ttggccatgt cggctgttat tacaggtgca gaaatcttcc
    39301 ttcccctagc tgatctgctc aatgtcacag aagaattagc tcgccttgaa aaagaattag
    39361 ctaagtggca aaaagagctt gacctggtca gtaaaaagct cagcaatgaa cgcttcgttg
    39421 ctaatgccaa gccagaagtc gttcaaaaag aacgcgacaa acaggctgat taccaagcta
    39481 aatacgatgc aaccgtagag cgcatcaagg aaatggagaa gttagtaagg taggatagtg
    39541 atcatctaag agccaattgg ctcttttttt gatatactgt caaggagtaa tcatcacaat
    39601 tatctatata agtcaaagga gtgtctcatg aaaaaaagag tcattggttg gttaggtgtg
    39661 ctggtaatag ggcttatgct tggtctgata tggtggaaat ggttagtggc agatcggcca
    39721 ctaacccaag caggtcaagg aagtcatgac cacagcagcg acaaaggcct cagtgccgca
    39781 taaggaaaaa atggaatcaa aagagcctga gacatcacat cagccagaag cctatcctga
    39841 tcttgctagc tatcaggaat tggctgttca tgtgtcgatt gcagaccaag tcatgaccat
    39901 tataggagat ggtaaggtta tttttaagac cagcgtgtca acaggagcaa aggaaagtcc
    39961 aacaccgaca gggacctttg tcattgagcc tgagcgagga gactttttct tcaatcaggc
    40021 atcagaagag ggagcttatt attgggtgtc ctttaaggac catgggattt atctgtttca
    40081 cagcctacca acagaccaat atggcaatga gattccagag gaggcagaga gactgggaca
    40141 gccagcctca catggctgtg tccgcatgag cagagcagac gccaaatggt tttatgacaa
    40201 tatcccagaa ggcatcagcg tcacaataga atagccctaa tctccctcag aatagcctga
    40261 gcagatagag gaagagcctg ttaatattag caggctttta aagctcctta aaaggctgca
    40321 aaaaggaacg aaaaaagacc tgaaacaggt ccattgatct aagagaagac aagtaactag
    40381 ccttctagca aagtgtttta aaaatgcgtt agtttagtag cttcgtgata atacaattaa
    40441 taatatttat ttaaaaaaac tgtaaatttc gaccactgtt cctggatttt ttcatttaaa
    40501 cgtttatgcc atgacttatg agcattctct ctaatttctt ttaggtatat attttctact
    40561 accctttttt gactatgttc tcgctctttt tttatttgct gtcttaaatt ctcttgtttt
    40621 ttctgttctt ctaactcttt ttgagctttc ttctgttctt gctctattat gtcttgaggt
    40681 ttagattctc ctacaatcca tatttctgaa cctaagacaa aaccatctga ggtaatatga
    40741 actctaaatt tatcaccatt agaagcaatt ttattatatg gaacatatgt ttcttctttg
    40801 gaatttgttt tttgtgttct cgctgattct aaagagaaca caatttttcc atcccacttt
    40861 gcaattggat agtaccggtt atttgttaag tcaccattgc tttttttttg gacttgtact
    40921 aattcagttt ccttatcatc ttcttcgact ttaaatattc taatcaaaga tcctggacta
    40981 gtttttacta ctatttcttt gtcattattt ttgattggtt taacgccaaa gtctcgagcg
    41041 ttttcccaat ctcttctaaa tcctattacc ttttggtcac caatttgtgg tgcttctgta
    41101 taatcatcat aaccataata gccttgccct aaaactggag aattttcata atcactattt
    41161 gcacttactt cgttgaaaca tattaaactt agtaaaggta aattaacgat taaactcatc
    41221 actaacttct tcttcatttt ttcttcctaa cctccattac tt
//
LOCUS       DARYUW010000012        40822 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYUW010000012 DARYUW010000000
VERSION     DARYUW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40822
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            141..1304
                     /locus_tag="TVW11_000544"
     CDS             141..1304
                     /locus_tag="TVW11_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1364672.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
     gene            1301..1981
                     /locus_tag="TVW11_000545"
     CDS             1301..1981
                     /locus_tag="TVW11_000545"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1364673.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            2094..3260
                     /gene="aroC"
                     /locus_tag="TVW11_000546"
     CDS             2094..3260
                     /gene="aroC"
                     /locus_tag="TVW11_000546"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1364674.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            3321..3662
                     /locus_tag="TVW11_000547"
     CDS             3321..3662
                     /locus_tag="TVW11_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1364675.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            3856..5208
                     /gene="gorA"
                     /locus_tag="TVW11_000548"
     CDS             3856..5208
                     /gene="gorA"
                     /locus_tag="TVW11_000548"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1364676.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5278..5718)
                     /locus_tag="TVW11_000549"
     CDS             complement(5278..5718)
                     /locus_tag="TVW11_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364677.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            5958..7100
                     /locus_tag="TVW11_000550"
     CDS             5958..7100
                     /locus_tag="TVW11_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1364678.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            7102..8316
                     /gene="thiI"
                     /locus_tag="TVW11_000551"
     CDS             7102..8316
                     /gene="thiI"
                     /locus_tag="TVW11_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1364679.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(8438..8680)
                     /locus_tag="TVW11_000552"
     CDS             complement(8438..8680)
                     /locus_tag="TVW11_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364680.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(9011..10060)
                     /locus_tag="TVW11_000553"
     CDS             complement(9011..10060)
                     /locus_tag="TVW11_000553"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1364681.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            complement(10584..10940)
                     /locus_tag="TVW11_000554"
     CDS             complement(10584..10940)
                     /locus_tag="TVW11_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364682.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            complement(11423..11771)
                     /gene="ssrA"
                     /locus_tag="TVW11_000555"
     tmRNA           complement(11423..11771)
                     /gene="ssrA"
                     /locus_tag="TVW11_000555"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            11862..12473
                     /locus_tag="TVW11_000556"
     CDS             11862..12473
                     /locus_tag="TVW11_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1364683.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(12520..13314)
                     /locus_tag="TVW11_000557"
     CDS             complement(12520..13314)
                     /locus_tag="TVW11_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364684.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(13324..14022)
                     /locus_tag="TVW11_000558"
     CDS             complement(13324..14022)
                     /locus_tag="TVW11_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364685.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(14022..14393)
                     /locus_tag="TVW11_000559"
     CDS             complement(14022..14393)
                     /locus_tag="TVW11_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1364686.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            14635..17745
                     /locus_tag="TVW11_000560"
     CDS             14635..17745
                     /locus_tag="TVW11_000560"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1364687.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            17825..18838
                     /gene="pfkA"
                     /locus_tag="TVW11_000561"
     CDS             17825..18838
                     /gene="pfkA"
                     /locus_tag="TVW11_000561"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1364688.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            18900..20402
                     /gene="pyk"
                     /locus_tag="TVW11_000562"
     CDS             18900..20402
                     /gene="pyk"
                     /locus_tag="TVW11_000562"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1364689.1"
                     /translation="MNKRVKIVATLGPAVEIRGAKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            20531..21088
                     /gene="lepB"
                     /locus_tag="TVW11_000563"
     CDS             20531..21088
                     /gene="lepB"
                     /locus_tag="TVW11_000563"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1364690.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            21265..23076
                     /gene="glmS"
                     /locus_tag="TVW11_000564"
     CDS             21265..23076
                     /gene="glmS"
                     /locus_tag="TVW11_000564"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1364691.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            23260..23595
                     /locus_tag="TVW11_000565"
     CDS             23260..23595
                     /locus_tag="TVW11_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1364692.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            23702..24343
                     /locus_tag="TVW11_000566"
     CDS             23702..24343
                     /locus_tag="TVW11_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1364693.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            24353..24982
                     /locus_tag="TVW11_000567"
     CDS             24353..24982
                     /locus_tag="TVW11_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1364694.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            24999..25835
                     /locus_tag="TVW11_000568"
     CDS             24999..25835
                     /locus_tag="TVW11_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1364695.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(25931..27169)
                     /locus_tag="TVW11_000569"
     CDS             complement(25931..27169)
                     /locus_tag="TVW11_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1364696.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(27272..28606)
                     /locus_tag="TVW11_000570"
     CDS             complement(27272..28606)
                     /locus_tag="TVW11_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1364697.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(28735..28821)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            29086..31377
                     /gene="pcrA"
                     /locus_tag="TVW11_000571"
     CDS             29086..31377
                     /gene="pcrA"
                     /locus_tag="TVW11_000571"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1364698.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
     gene            31790..32035
                     /locus_tag="TVW11_000572"
     CDS             31790..32035
                     /locus_tag="TVW11_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1364699.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            32083..32664
                     /gene="amaP"
                     /locus_tag="TVW11_000573"
     CDS             32083..32664
                     /gene="amaP"
                     /locus_tag="TVW11_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1364700.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            32674..32862
                     /locus_tag="TVW11_000574"
     CDS             32674..32862
                     /locus_tag="TVW11_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1364701.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            32875..33414
                     /locus_tag="TVW11_000575"
     CDS             32875..33414
                     /locus_tag="TVW11_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1364702.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            33452..33649
                     /locus_tag="TVW11_000576"
     CDS             33452..33649
                     /locus_tag="TVW11_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1364703.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            33659..34147
                     /locus_tag="TVW11_000577"
     CDS             33659..34147
                     /locus_tag="TVW11_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1364704.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            34303..34944
                     /locus_tag="TVW11_000578"
     CDS             34303..34944
                     /locus_tag="TVW11_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1364705.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(35061..35609)
                     /locus_tag="TVW11_000579"
     CDS             complement(35061..35609)
                     /locus_tag="TVW11_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1364706.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            35732..36433
                     /locus_tag="TVW11_000580"
     CDS             35732..36433
                     /locus_tag="TVW11_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364707.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            36445..39084
                     /locus_tag="TVW11_000581"
     CDS             36445..39084
                     /locus_tag="TVW11_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1364708.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILTSHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            39160..39756
                     /locus_tag="TVW11_000582"
     CDS             39160..39756
                     /locus_tag="TVW11_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1364709.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            39766..40728
                     /locus_tag="TVW11_000583"
     CDS             39766..40728
                     /locus_tag="TVW11_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1364710.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT        11867 a         7388 c         9352 g        12215 t
ORIGIN      
        1 acttccttat cattttttcc taaaagatat aatctccaaa taaaatctca gattaaatta
       61 taccaaaaat atggagctaa tgcttgcaat aagtttaaat ctagtatgat tttttaatag
      121 tttttgttat aatagaaact atgaataagg tctgtattaa tccccttgtt gaacgcaaga
      181 tagcagcagg gatacaatta ctagatgaaa aggattttga tggcaccatt tgggactacc
      241 agttagtgca gcttgtgaat tcatctcatc agctcatcgg cacagcttac ctttcaaagc
      301 aacataaggg agtaggctgg tatctaggaa ggtctgttaa gaaattgtcg gtttcttatt
      361 ttgtgacctt atttaagaca gctaagaaga aaagagagca ttttgccgcg tctgaatgga
      421 caaatgctta ccgtcttttt aaccaagacg gtgatgattt tggaggacta accatagacc
      481 tctataagga ctttgcttta ttttcttggt ataatgtctt tgtttatcaa gaaaaggagc
      541 ttattattca ggcttttcga gaggtttttc ctgaggtcag gggagcttat gaaaagattc
      601 gctttaaggg accagataag gagacggctc atttgtatgg cgcgtttgct cctgatacct
      661 ttaccatttt agaaaatggc gtagcctatc aggtattttt aaatgatggc ttgatgacag
      721 ggatttttct tgatcagcat gaggttagac gaggtctggt ggacggcttg gcgcttggaa
      781 agactgtttt aaacctgttc tcatatacag cagctttttc tgtagctgca gcaatgggcg
      841 gtgcagttga gacaacctct gttgatttgg caaagcgctc cagagagtta tcaaaggctc
      901 attttgttca aaatcagttg gacctatcca gtcatcagct tgtggttatg gacgtttttg
      961 actattttaa gtatgctaag cgaaagcaac tttcttttga tcttattatt attgatccac
     1021 caagctttgc cagaaacaaa aagcagacgt tttcagtgag taaggattac catcaattaa
     1081 tcgctgaggc tctagaccta ttggccccca agggaacaat tatcgcttca acaaatgctg
     1141 ccaatatgac tgttaaccag tttaaaaagc aaattatcaa aggattggga ggcaggccat
     1201 tagctcagat gacacttgag cagcttccaa gtgattttac tatcaataaa gcagatgaaa
     1261 gaagtaatta tttaaaggta tttactataa gggtacgaga atgaaaattg tagcaccagt
     1321 catgccaaga aatgttgaag aggctcaatc tatcgacgtt tctaaatatc aagatgttaa
     1381 tttaatcgag tggcgagcag actttcttcc taaggaggat attgtttctg tagcgccagc
     1441 tatttttgaa aaatttgcag gtagagagat tatttttacc cttcgtacaa gtcaagaagg
     1501 agggcatatt acactttctg atcaggaata cgttgatttg atcaaggaga tcaatgcgat
     1561 ttataatcct gactatattg actttgaata ctttagtcac aaggctgtct ttcatgaaat
     1621 gcttgacttt ccgaatcttg tcttgtctta tcacaatttt gatgagacgc ctgaaaatct
     1681 gatggaggct ttttcggaga tgactaagct agctcctcgc gttgtcaaga ttgctgtcat
     1741 gccacagagc gagcaggacg ttttggattt gatgaattat accagaggct ttaaaacact
     1801 taacccagag caggaatttg caaccatgtc aatgggaaag ctaggcagac tatcacgctt
     1861 ggcaggtgat gttgtagggt cctcgtggac ttttgtgtcc ttagatcaag ccagtgcacc
     1921 agggcaggtt tccttggctg atatgaaaag gattcttcat gttttggaat ctgaggattg
     1981 ataagatacg gtaacagaca ttattctctt ggatagctta gaataatgtc ttttagttgt
     2041 ctagaggagg gcaggtttgc tttttatgtc tatgattgat aaatggagga ataatgaggt
     2101 atttaacagc aggtgagtca catggacaag ctttgacggc cattatagag ggaattcctg
     2161 caggcttagc attatcagct gagcttatta acaaggaact gaagcgtcgg caggggggat
     2221 atggtcgtgg cgcacgcatg cgcattgaat cagatcgtgt gcatatctct tcaggtgttc
     2281 gtcatggcaa aacaacagga gcaccaatta ctttaaccat tcaaaacaag gaccatcaaa
     2341 aatggctaga cattatggct gttgaggctg ttgaagagca aatcaagttc aagcgtaaaa
     2401 tcactcgtcc acgccctggt catgctgact tggttggggg gatcaaatat cgttttgatg
     2461 atttaagaaa tgcgcttgag cgctcctctg ccagagaaac agcgatgcgt gtggccgttg
     2521 gtgcaattgc taaggcaatc cttactgagc ttgggatcga aactgctaat catgtcctag
     2581 tttttggtgg tatcgaggta gctgtgcctg aggcgatgtc ctttgcagat atcaaaaaag
     2641 tagcagagtc ttctgattta tctattgtca atcccaagca agaggcgact atcaaggccc
     2701 atattgatca agtcaaaaaa gaaggagata cgcttggtgg tattattgaa acactcattc
     2761 atggcttacc agcaggctta ggttcatatg ttcagtggga tcgtaaatta gacgccaaaa
     2821 tcgcgcaggc tgtcctgtct atcaacgcct ttaaaggggt cgaatttggt atgggctttg
     2881 acatgggcta ccaaaaaggc tcgcaggtca tggacgacat catttggcat gagacaagcg
     2941 gctacagtcg tcgaacaaac cgactaggtg gctttgaggc aggtatgact actggtcagc
     3001 ctattgttgt caaaggggtg atgaagccga ttcccaccct ctacaagccc ctaatgtctg
     3061 tggatactga gacgcacgag ccttacaagg ctactgttga gcgttctgat cctacggctc
     3121 tgccggctgc cggtgtcgtg atggaaaatg ttgtagcaac tgtcatcaca aaagagattt
     3181 tggaacaatt tccatcagac aatatgaccg atttaaagca ggcttttttt gcctatcgtg
     3241 actatgttca tcatttttaa gcgacaaatg gcttgatatt gtgatatgat aaggataata
     3301 aatgataaaa ggagatccag atgtcccaag atatttatga ttatgccaat aagcttgagc
     3361 gagctgttcg tgcgctccca gagtatcgca aggccttgga agccagagaa gagattaagg
     3421 cagatgaggc tgccagtcag ctatttgatg agtttgttgc tgtgcaagaa aaattgcaag
     3481 gactcatgca gaccggtcag ctgccaacag agacagagca ggcagatatt caggctctca
     3541 gccaaaaaat tgaggccaat gacctattaa aagggtattt taacgctcag caggctcttt
     3601 ccgtctatgt taatgatatt gaacggattg tatttgcacc attgaaggat ttggccaagt
     3661 agagctaagc tggcttagga ttaagagaag aaaggattgt tgatgcttat cacaatcttt
     3721 ttttgtcgta gcagggattt gagacacaag ttattttatg ttatagtcaa atgacagtag
     3781 attaaaataa agcaataatg atagcttaat aacaaatcta ttgaggcaag cattaagagt
     3841 aaaggtggta aattaatggc aattcagtat gattatattg tgattggtgg tgggagcgct
     3901 gggattgcct cggcgaatcg tgcagcaatg tacggtgcta aggtcctatt agctgagggc
     3961 aaggctattg gagggacctg tgttaatttg ggctgcgtgc ctaaaaaggt catgtggtat
     4021 ggcgcacagg tagcagaaac gattcatacc tatgcgaagg attacgggtt tacggtgtta
     4081 gaggataggt ttgattttaa aaccttaaaa agcaatcgtc aggcctatat tgatcgtatt
     4141 catgcctctt atgagaaggg ctttgagcat aacggggttg atcgtattta tgattatgca
     4201 cgatttattg atcagcatac ggttgacatt gcaggtaaga cctatacagc cccccatatt
     4261 ttaatcgcta ctggtggtca gcctattttt cctgacattg aaggagctga gctggggatt
     4321 agctcagatg gtttctttgc tttagatgat attccaaaac gaacagcagt tgtcggtgct
     4381 ggctatattg ctgttgagat tgcaggagtg ctcaatgccc taggttctca gacggatttg
     4441 ctggttcgct atgacaggcc actgaggacc tttgatcagg atattatcca ggttctggtc
     4501 gatgagatga aggtatctgg accaaggctg cataccaatg ccgatgttac taaggttacc
     4561 aaggctaatg atggctctct tcaagtgcat ttgtccgatg gtcgtaggct tgaagtggac
     4621 caagtgattt gggcaattgg ccgcaagcca aatgtgacag gctttggctt ggagcataca
     4681 ggagttgagc tggataagaa gggctatatt gctgttgacg cttatgaaaa cacatctgtt
     4741 gatggcatct atgctgttgg tgatgttaat ggaaagcttg ctttgacccc agtcgctgtc
     4801 gcagcaggtc gtcgcttggc agagcgcttg tttcataata agcccaatga aaagcttgat
     4861 tataacaagg ttgcgacagt tgtctttagc catccgccaa ttggctcgat cggcttaaca
     4921 gaagaggcag ctattcaagc ctatgggcaa gcggctgttc gtgtctatca atcacaattt
     4981 acgtccatgt atacagctat tactagtcat cgccagccct gcctaatgaa attgatcgtt
     5041 gcaggagaag aagagaccat cgttggtctg catggtattg gttatggtgt tgatgagatg
     5101 attcaaggct ttgctgttgc cattaaaatg ggggctacta aggctgattt tgacaatact
     5161 gttgccattc accctacagg tgctgaagag tttgttacca tgagataaca gcacatgata
     5221 aaacacgata gcagacaatt cagagcttat ctgaattgcc tgttatcgtg ttttgtgtta
     5281 tggattgctt gtactgttag gagctggctc attagctgtg ggttgattag cagccggtgc
     5341 ttccgtttcg gtattctgtt gtttttctgt atccttagta gcaggatcag ctgagctagg
     5401 agtagtatgt gtcgcctgag taccgctaga atcagaatta gtttctgtct tgtcagtctc
     5461 ttccttattt gagtgtgacg actccttttc aataattttc acaatcgttg atgttgatga
     5521 cggagaggaa tcgcttttgg gttgctcatt tgatggttgt agagctcgat taatagtgat
     5581 tgtcgctaca acaatactca gaacactacc aactaaggca atggtttttt gaagggcggt
     5641 aaagccagtt ttaatatgct ttgtgggaat acttgctgat tttttaggct tttgttgacg
     5701 tgaataatgt gatgacatga gaatatctcc tttaacgagt cataggctag ctaaagtcaa
     5761 atgctttagg tctttaatgg ctaacaggca tttcagactt agctctatca tctaccagta
     5821 taatctagaa caaaaatcaa gtcaacggtt taccttattg tctaggatag agttgtccta
     5881 tcctgcaaaa agatctattt tttcatttca tcaaatttgt gatacaataa agtattgaat
     5941 aaaaatgaag gtgacacatg atttattttg ataatgcagc cactaccaag ccttacgaag
     6001 aggcacttaa aacgtatcag gaagtggcca gtaagattta cggcaatccc tctagtctcc
     6061 atcagctagg agccaatgcc agtcgtatat tggaggcttc gcgcaggcaa atagcggcct
     6121 tacttgatgt agaggccaaa gagattttct ttacctctgg cggaacggaa agcgacaatt
     6181 gggctatcaa ggggattgcc tttgaaaaat ctcactttgg taagcacatc attgtctcag
     6241 ccattgagca cccagctgtc agagaaagcg ccaaatggct agaaagtcaa ggctttgagc
     6301 tgtcttatgc tcctgtcaca gataagggag ttgttgatgt caaaaagcta gctgccttaa
     6361 tccgaaaaga taccatatta gtttccatta tggcggttaa caatgagatt gggtcaattc
     6421 agccgattgc agccatatca gagcttttgg ctgataagcc caccattacc tttcatgtcg
     6481 atgctgttca ggctattggg aagcttcctg ttgaggctta cttaaccgcg cgtgttgact
     6541 tagcttcttt ttctggtcat aaatttcatg ctgttcgtgg tgttggcttt ctttataaaa
     6601 aatcaggaaa gcgaatcact cccttattgg tcggtggcgg tcaagaagat gagctacgtt
     6661 cgacaactga aaacgtggca gctattgcaa gtatggccaa ggctttaagg atcatcacag
     6721 aaagacagga tagatctcaa gcaaggatag cagccatgaa aaaggttatt tatcaagcct
     6781 tgcaggccta tgaggatacc attctctttt ctgagataga tgattttgct cctcatattc
     6841 tgacctttgg tataaagggc gttcgtggag aggttattgt gcacgcattt gaaaagcatg
     6901 agatttatat atcaacaacg agtgcctgct catcaaaggt tggaaagccg gcaggaacct
     6961 tagtctcaat gggaattcca gcagcattgg ctcaaacagc agtccgtatc agcctagatg
     7021 atgataatga tatgggacag gttgagcaat ttttaacgat ttttaaacag atttatgaaa
     7081 aaacacaaaa ggttagataa tatgaaatat tcagaaataa tggttcgtca tggggagtta
     7141 tcgaccaagg gaaaaaaccg tatgcggttt attaatcggc taaaagctaa tattcaagat
     7201 gttctttctg cctattctga ggtgacagtc agatcaactc gagacaggac ccatgtttta
     7261 cttaatggtg cagatgatag gtctgtgatt gaagccttaa agccggtgtt tggtattcag
     7321 ggcttatctc ctgtctataa agttgaaaaa agtgtccctg tactgatagc agcagttcag
     7381 gagattatga gctccttgta tcgcgaaggg ctaaccttta aaatatccag caagcgtagt
     7441 gaccatcagt ttgagctaga tagccgcgac ctcaaccaca ccttaggagc agccgtcttt
     7501 gaggctttgc cgcatatcaa ggcacagatg aaaaatcctg atgttaccct aaaggtcgaa
     7561 attcgtgatg aggctgctta tctgtctcac gaagatataa agggagctgg agggctgccg
     7621 gttggagctt caggaaaggg aatgctgatg ctatcaggtg gtattgattc accggttgcg
     7681 ggctatctat ccctgaaacg aggtgttgag attgaggcag tgcattttgc aagcccaccc
     7741 tataccagtc ctggtgcgct aagaaaagcc aaggatctaa cgcagcgctt aacacgtttt
     7801 ggaggtaata tacagtttat cgaggttcca tttaccgaga ttcaagagga gatcaagcat
     7861 aaggcacccg aagcctattt gatgacactt actagacgct tcatgctgcg gatcacagat
     7921 gctattcgtg agaagcgaaa ggctttagtg attattaacg gtgaaagctt aggacaggtt
     7981 gcaagccaga ccttagagag catgcaggct attaatgcag tcacttcaac tccgattatc
     8041 agaccagttg tggcaatgga taagctagaa atcattgata tcgctcagca aattgacacc
     8101 tttgatattt ccattcagcc ctttgaagac tgctgtacta tttttgctcc tgatcgtccc
     8161 aaaaccaatc ccaagctagc aaatgttgaa cgatatgagt ctcgctttga tgtcgacgga
     8221 ttggtcgagc gagcagtggc agggatcaga gtaactgaga tcactcctga aatcgaaact
     8281 gacagcttat caacgcttat tgaggaattg ttgtaggagg tgcgcaccta gccctacaac
     8341 ataagcagtc tatctaaaca gtcaaaaaaa gccagaccta ttagttatta aaggctctgg
     8401 cttttgtttt tagctgattt tgctcaaatt ctcttattta gctgctaaaa tactggataa
     8461 tctcatcaga aaggacctcc tcgtattgtt tcatagcctc ttcattggtt aagcccatcg
     8521 tctgtaggta ggctttcaag gattcggcaa tgccatgtct ggtcaaatcc tctaccgtaa
     8581 ccgcttgaat aggcttttcc tgaacagcct cagctagctg caaagacaat gagtgacagc
     8641 cagttaataa gagactggct aatagtgtac aacttatcaa tatagatttt tcatatattt
     8701 ccctcctttc atgaaaatta tatgaaaaca accataaatt gtaaactatt tggatttatt
     8761 tttagtataa tattcgtatt ttatgttcaa aaaatgattt ttttattaag ataaataata
     8821 acgtttgttt tttatgtcag gtatctagtt tacttatctt agaaaagaac aacaggcaca
     8881 ttaatgttta acaaaacaag agcttaaaga gttcatgaca agctttaacc aatgacagtg
     8941 agctaatagg gctattgtta gacgaaaaaa cagaccaata agcacttggt ctgttcctaa
     9001 tgatgactgg ttagctcagt ttctgccata tgtccttgcc actggaaagc gtaaataagc
     9061 ctaatacttg agcgccaatg ttttctcctt ctattttctt ggcagaaatg gcgacatgtc
     9121 tatgagcatt aatgccgaca aaatattttt tcataccaat agacgcatta gcatctgagt
     9181 ctgtgacata gatggcctca aggtttcctt cagcattaaa atcagctccc cacaagttaa
     9241 tcacatggct aatgctaaca ttggcgtagg tatgtgataa agcaagggct cttccttcag
     9301 tcagttcttg cttgataatg gtgctgatgt catttagtcc tttatttttt aaatcatgac
     9361 gagctgtcaa gagcgttgtc tgatctcctc tggtgaaaac agcatcgaaa ataccacctc
     9421 gtttgtcctt gtcctgataa ggtcgattga catcagtaga ctgtgtttta aacacattta
     9481 agtagtaacc attgataaac atgtctagaa caagatcagg cataaccccg agttgacgtg
     9541 ctgatagatt tggaaaggct ttatctctaa aataattaaa aagctgacta ttggtttgac
     9601 tgtccttggt atcgatagca gctttcaaat caaatagctc ttggttgtta aaaatgattt
     9661 tttgcttttc agggtgttta cttaaatagg cttcaatctc tgttttattt tgatcaaacc
     9721 accaatgcag catattacct gccgttgctg cgccacacaa gagattatcc ttcccatcga
     9781 aggccttggt gatatcgtac cagccttgat gagcaagata tggcgcatgg atcacatctt
     9841 cgttattata tcgaaactgc tcgggtgtta gtggtgtaac acctttggtc catacagaag
     9901 tgatctgatg tggtacttct ttggcataag cttccgtagc attcctttgg taatcgtcag
     9961 cataagtaat gtttgaactc gccaggctaa aaatagctat agcagttaag agaccagctg
    10021 ataaggagtg aggtttattt ggataagcta ttgttttcat ataacccttt cttgttatgg
    10081 tgatattatc attaaataat gttaatgaca tttatatatt atcacaatat tttgttgaga
    10141 caatgctttt gataagcttt atttattagt aaatagtgat gagatagtag agatgctggc
    10201 agactggatc tctataatgg atatttcagc ttggtttatg ttagcgttac ctattttacc
    10261 aatgatgata ccgtttggta ttgttggtgt catgccttag acatgagctg ttattattga
    10321 gaccactaat aagagctagt gtaggctttg atgttattgg gattcttgca caatcttagc
    10381 caagcttagt cagcaaatca gggcattagc taggatagta aggacaatgg tgcagttatt
    10441 acttgattag ctaggcggac gatttaggag atggtctggt tactaagcag attgacaaag
    10501 agaagcatag ctctatcaag ttaaaaccgc tcggaaggtt gtctgagcag ttttgatcta
    10561 tgataactta ttgggttatt tcattaaaaa ggggaatagt cgttataaaa tttagctaat
    10621 tcagatagaa ctgcagaaat aacttcacta cgagttttac ccttaaagtc agctagtagc
    10681 tttttgtaat cttgatcagc catagagtcc gaataaagag tggcatcaaa atggttaagg
    10741 cctagactct ccaagaatga caccaaatca tcgtatcctt cttgcttagg cgtcaaaaga
    10801 tattccacgt caccataaac atagtcatca gctttgctga tgtgggttga agctgttagg
    10861 cagactcctg ccaaagctag ggcagccatt gtagaaacca taaatttctt acaagcttgt
    10921 gtcatataag tgtcctccat ttccaacggt tcctttgtcc gtcgttattt ttgtgatatt
    10981 ttccttatca caatgttagt ttaactcaaa atctgtcaaa agtcaaatgt ttttgtaatt
    11041 aaattaataa agtgttttta aaaaattaaa taaatgtagc ttttggaata attaaattat
    11101 tgaaattttg taaagaagca caatatcata acagatgata tctataaagc agcagtaaat
    11161 gatgtctata taacaggcaa tacagggcaa ttatccgaaa aaatttgata atgtgctgtc
    11221 aatgaagcaa gtagaagaag tattataaaa aaataaatat aagattagct aaagagaaaa
    11281 ttcaagctgt tcttaaagga ttttttggcc ttttttttgc tatcactttc atagaaactt
    11341 acggtaaccc acgaacagga caaaaagaaa aaaccttgat ttaacaaggt tttagtaagt
    11401 tatggtaact tacggtaagt attgatggag ctggtgggag tcgaacccac gtccaaacac
    11461 ctgctaacct atttgtctac aaccataggt tatgtcttac tttaacagac caaggacaca
    11521 taactcaagc catcagcctg cgagtctagg gttctctttt taggtgacta gacaatcacc
    11581 taaacgtagc ttgctgtttt gagacctcta ataagacaca agcaatccta tagaagtcac
    11641 gccggctggt ttttaggcag ctaaagcgta agttgtgtta ttttttgcag ttatatttaa
    11701 ctggcatttt tacatctgcc gatgagttgc aaaataggcc tcataatgcc tgtcgaatcc
    11761 gtaacaaccc cataaaaagg cgtatgagat acttacggat gctagtatag caaaattttt
    11821 ttaaaatggc aaaaaaatag cgcttatggt atgatgaagc tatgagaaat aatgagttga
    11881 agccttatgt gatatggcaa aaagtgatta agctattagg aagtctggct ttagtcggat
    11941 cttttttgct agccttttgg ttttacaggc ttggcatttt aaatgacagc aatgcactca
    12001 aggatcttgt tcatagtcac aaggtttttg gcccccttgt ttttgtcggt gtgcaaattg
    12061 ttcagattgt ttttcctatt attccaggtg gtatgacaac tattgcaggc tttttgattt
    12121 ttggcccttt gctgggtttt ctttataact atgttggtat cttcattggt agtgtgattc
    12181 tgtttttact tgtgaagacc tatggtaggc gctttatttt actgtttata gaggaacaga
    12241 ccttttacaa gtatgagaga aaattagaga tgccatatta tgagagattg tttattctct
    12301 gtatgctttc tccgatttca ccagcagata ttatggtcat gattactggg ctgacagaga
    12361 tgtcgttgaa gcgttttgtg accattattt taatcacgaa gccactatca attattggct
    12421 acagctatct ttttatcttt ggaaaggatt tgatcctatg gtttttccat taaaaaagtc
    12481 taggcattgc ctgataagca gtggctagac tttttgttat cattggatat taagcttgtt
    12541 tttgatgatg aagtgagtag caacgtaaag gataatgcct tcaactagtt gctctatgtt
    12601 taaaatagat atggctgtat gatcaccgaa atagagtagc gagtctgagc tatttgggtt
    12661 gacggtgaaa aacgcatcat ttaaataagt catgacgaca ataatgataa taactaaaat
    12721 gaaataggca caaaatgcca tcaaaccacg acgatttgaa aatagctgac caattgagat
    12781 tgctagataa atcaatagta tacttgttat ggttgacaaa agcatgtaga tgaggataga
    12841 agcattttcg actaagtttt ctggcttcat aattgtcttt agcaccttta gtagataggt
    12901 aaagtcaact gttggcgcta ttaaaataaa gataccgatt aataggttaa tgccattaaa
    12961 aatactgcaa acaaaggacg ctaacagctt ggacaagata atctgatgtg ctgttactgg
    13021 tagtgtcagt gttaagtatc cctcgcgccc aaagacattt ttgttaaagc gattaatgat
    13081 gattaatagc gttgataaga atgatccggc aatcagagaa ccaaacgtta atgagagtgt
    13141 gagaggaacc attttgtttg ccagacttgt tgttaaacca acctcgtcag gattgtttgt
    13201 aagcgtattg atggtaaaag aaaggactat cgcgatagca atgacaccgg cattaagcgc
    13261 aaaataccac ttgccaattg atctaaattc gtattttaat aattttccaa acatgcctac
    13321 ctcctaaacc ttgtagatct ctctaaataa tgaatcaatc gattgctgat gctgaactcg
    13381 taaatcatca gcgtttccag aaaggcagag cttaccattt tttaagaaaa tagcttcatc
    13441 aagtacaggc tcaatgtctg agatgaggtg agtagaaatg ataacagagg cttgctcaga
    13501 gtaattatta ataatggttt taagaatata atctcttgct gccgggtcaa cccctccgat
    13561 aggctcatca aggatataga gctttgcttt gcggctcatc acgaggataa gctgtgcctt
    13621 ttccttattt ccctttgata ggtttttaaa gcgctcttca gcatctaagt ctaaatcctt
    13681 caggagactg gtcgctttat ctctgtcaaa atcggcatag aaatcaccaa aaaagtctag
    13741 catatccttg attttcatac tttcattaag ataggtcgta tctggtaagt aagaaatgat
    13801 ttttttagtt tctacagatg gtctaaagcc gtcaataaca atgtctccct tgtctggctg
    13861 taaaagtccg ttgattagct taattagtgt agttttgccg ctaccatttg gtcctagtaa
    13921 gccgataatt tttccagaag ggattgttat ggttaaatca tcaatagcta attgtttttt
    13981 gtaagatttt gagacgtggt gcagctgtaa tagttgtgcc attagtttga tccctcctct
    14041 aaaaaggtac ttaaaacagg aatgatttct gaacgttcaa aacctatttt gatcatattg
    14101 ctaataaagg acttgagctc gttgatggcc agctctcgtc ttttgcgcgc gataagctct
    14161 tggttatctg ttacaaaccg gccggcagtt cgttgcgagt aaactatgcc ttcacgatct
    14221 aattcggtaa gtgctctttg catggtgttg ggattaacgc cggcaatttc agcatattct
    14281 cggacagtcg gcagctgatc tccacttttg atctcttggc tgacaatttg cagcatgata
    14341 tgctgtgcta tctgtgcgta aataggagat ttctcatcaa atttccaaga catactgtct
    14401 cctttctttc taaaatctgc gattaatatt tgtactaatt aaatgataca aaaaaacgat
    14461 tgacttgtca agccttgtgt gtcatctcta gttacatact ggcttgcaat gctagtggga
    14521 ttcctgctga tagtggtgca gtaaagacag atcactgcta ttaaaagctt aaaatctggg
    14581 cagtaaagtc tttttcatag tataatggta gtaagaacgc taaaggagat gtccatgttt
    14641 gctcagttag atacaaaaac agtttattcc tttatggata gtttgattga tttagaccat
    14701 tattttaaac aagccaaacg attaggctat caagccatag ggattatgga tcaggataat
    14761 ctatatgggg catatcattt tattaagggc tgtcaaaggc atgggcttca gccgatttta
    14821 ggtcttgagg tggctattac agttaaagag caggctctta cgctgaagct tgttgcgaaa
    14881 aatgatacag gctatcagca gctcttaaag ctttcgactg aaaaaatgtc tggagaccta
    14941 gacctagaca cattggtgca gtatttagaa gggatagcag ttatcgttcc ttttagtcag
    15001 agcttgcgtg atttagggct tccttttgat tacttcattg gcattgatga ggcaagcgac
    15061 ttgtcaaaga tagactctac agaaagactg attccgctta gaacggtacg ttattttgat
    15121 aatgctgaga ctgagactct gcaaatgctg catgccattc gtgataatat tagcttagca
    15181 gatacggctc tagtagccaa ggatcagttt ttagcgcctt gtcaggagat gacggctatt
    15241 ttccaggaaa agtgccctga ggctttggtg aatctcgtaa atctaacagc ttcgattgct
    15301 tatcattttg atactgattt aaagcttccg agatttaacc gcgataagcc agcaaaagaa
    15361 gagctaagag aattgaccga gtctggtcta agagaaaagc aattatggaa ggagccttac
    15421 caatttcgtc tggcagagga gctggctatt atttcagata tggggtttga tgattatttt
    15481 ctcattgtct gggatttgct gcgctttgga aggagtagag gctattatat gggcatgggg
    15541 cgtggttcag cagcaggcag tctagtggct tattcgttgc gcattactgg gattgatcct
    15601 gtcaaaaaca atttattgtt tgaacgcttt ttgaataaag aacgctacag catgcctgat
    15661 attgatattg atttgcctga tatttaccgc tcagagtttc ttcattatgt tcgagaccgg
    15721 tatggtagtg agcactcagc tcagattgtt accttttcga cttttggtcc taagcaggct
    15781 gttcgtgatg tgttcaaacg ctttggtgtc ccagaatacg agctaacaag cctaactaaa
    15841 aaaattgggt tcaaggatac cctgagcact gtttatgaga aaaatatagc cttcagacag
    15901 accattaata gccgcttaga gtttcaaaag gcatttgaga tagctaagcg cattgaaggc
    15961 aatccaagac agacctctat tcacgctgct ggtatcgtga tgagtgatga ccatctgacc
    16021 aaccatattc ccttaaaaaa gggggaggat atgatggtga ctcagtatga tgccagtgct
    16081 gttgaagcta atggcttgct gaaaatggat tttcttggtc tgagaaattt gacgcttgta
    16141 cagaaaatgc aggaaaaggt ggtcaacgat tacggtcttt caattgacat tgaagctatt
    16201 aacctagagg atcctgaaac gatagccttg tttgctaggg gtgataccaa gggcattttt
    16261 caatttgaac agcatggtgc gattagcctg ttaaaacgga tcaagccgac tagctttgag
    16321 gaaattgttg cgacaaccag cttaaataga ccgggagcaa gtgattacac gcagaatttt
    16381 attaagcgcc ggcagggaca ggaaaacatt gatctaatag atccggtgat tgctccgata
    16441 ttagagccaa cctatggtat catgctttat caggagcagg ttatgcagat tgctcaagtt
    16501 tatgcaggct ttacacttgg aaaggccgat ttgctacggc gtgctatgtc taagaaaaac
    16561 ctcgttgaga tgcaaagaat gcaggaggat tttctgactg gtgctagagc cttgggtcgc
    16621 tctgaggaga cagccagact attgtttgca cgtatggaaa aatttgcagg ctacggcttt
    16681 aaccgcagcc atgcctttgc ttatgctgcc ctagcctttc agctagccta ttttaaagcg
    16741 cactatcctg aggtattttt tgatgtcatg atgaattatt ctagcagtga ttacatcaca
    16801 gatgcgttag attttggctt tgaggccgcg caggtgacga taaacaccat tcccttcaat
    16861 gataagattg agcgtcataa gatttatatg ggcttaaaaa acatcaaggg tcttcctaga
    16921 gaattttcgt attggatcat tgaaaatagg ccctttacca gtgttgaaag ctttttgtgc
    16981 agcattcctg aaaaatacca gaaaaccagc ttcttagagc cccttatcaa aataggcctg
    17041 tttgatgggt ttgaaaaaaa tcgccaaaaa atcattaaca acttagaagg actgctaacc
    17101 tttgtcaatg aattgggatc actttttgcg gattcctcct ttagctgggt agagactgag
    17161 gattattcag ctgctgagaa atattacttt gagcaggatt tgcttggtgt tggcatgagc
    17221 aagcacccct tgctagctgt cgctgaaaaa agcacagtag cagtcacacc aatcacaaag
    17281 ttagtgaagg atacagaagc tactttgctg gttcaaatag atgcgatcag ggttattcgg
    17341 acaaaatcaa gcggacagca gatggccttt ttgagtgtta ctgataccaa acagaaatta
    17401 gatgttaccc tttttcctga gcaatatgct gtctataagc aagacctaaa agaggggcat
    17461 atttactata tcaatggcag ggtaaaagaa agagataacc gcttgcagct agtctgtcac
    17521 cagcttcgat tagctcagag tcaaaggtat tggctattgg ttgaaaacca tcagcatgat
    17581 gctgctattt ctgacatatt aacagccttt tcaggggaga ctcctgttat tatccattat
    17641 caagaaggca aagaaacctt agagttaaac catattaggg ttgatgttag taaggatttg
    17701 gaggaggcta ttagccccta cgtgttgaaa acggtttttc gataaaaata gcgaattagt
    17761 gaagtaattt gcaaacgaat gtgctataat aaaaacgtta aattaattaa aggagtacca
    17821 aaaaatgaaa cgtattgctg ttttaaccag tggtggtgac gcccctggta tgaatgctgc
    17881 tattcgtgca gttgttcgta aagcaatttc agaaggaatg gaagtctatg gtattaaccg
    17941 cggctatgct ggtatggttg atggtgatat ctttccacta ggctcaaaag aggttggtga
    18001 taagatttct cgcggcggga ccttccttta ttcagctcgc tacccagagt ttgctcagct
    18061 tgaggggcaa ttggctggta ttgagcagct aaaaaagcat ggcattgaag gggtagttgt
    18121 cattggtggt gatggttctt accatggtgc gatgcgcttg actgagcatg gcttccctgc
    18181 agtaggtatc ccagggacga ttgataacga tattgctgga acagactata ctatcggatt
    18241 tgacactgcg gtcaatactg cggtagaggc tattgataag cttcgcgata cctcatcaag
    18301 tcatggacgg acctttgttg ttgaagtgat gggacgcaat gcaggtgata tcgcactttg
    18361 ggcaggtatt gcaagtggag cagatcaaat catcgttcct gaagaggaat ttgacattca
    18421 taaagtggtc tcaacaatta aagacgattt tgaaaataga ggaaaaaatc accatattat
    18481 cgttttagct gagggtgtta tgagtggcga ggcctttgcg cagcagctaa aagaagctgg
    18541 agatgaaagt gaccttcgtg tgacaaacct tggtcatatc cttcgcggtg gctctccaac
    18601 tgcgcgtgat cgtgtgattg cgtcatggat gggagcgcac gctgttgagt tgctcaagga
    18661 aggcaaaggt ggcttggctg ttggtattca taatgaagag cttgttgaaa gtccgattct
    18721 tggaagtgca gaggacggtg ccttgttcag ccttactgat gagggtaaca ttgttgttaa
    18781 taacccgcac aaggctcgct tagactatgc tgctttgaac cgttcattag cacaatagga
    18841 taagtaagat ctggtaatct ttgttaatca actaaaaaat aagggagttt cataataaaa
    18901 tgaataaacg tgtaaaaatt gttgcaacac ttggtcctgc ggttgaaatt cgcggtgcta
    18961 aaaaatatgg tgaggacggc tattgggctg gtcagttgga cgttgaacaa tcagctaaaa
    19021 agatcgctga attgattgaa gcaggtgcta atgttttccg ctttaacttc tcacatggtg
    19081 accacaaaga gcagggtgac cgtatggcta ctgttcgtct tgctgaaaag ctggcacgtc
    19141 aaaaggttgg tttccttttg gatacaaaag gaccagaaat gcgtacagaa ttgtttgctg
    19201 acgatgccaa agaatatagc tatgtgactg gtgagcgtat tcgtgttgcg acagcacaag
    19261 gcattcaatc aactcgtgat atgattgcct tgaatgtagc tggtgctctt gatatttatg
    19321 atgaggttga ggttggccac actattctta ttgacgatgg aaagcttggc ttaaaggtta
    19381 tcgagaagga cattgcaaag cgtgagttca tcgttgaggt tgaaaatgat ggcatcattg
    19441 caaagcaaaa gggtgttaat atccctaata ccaagattcc tttcccagcc ttagcagaac
    19501 gtgataatgc tgatattcgt tttggtcttg agcaaggtct taactttatt gctatttcat
    19561 ttgttcgtac tgccaaggac gttgaagagg ttcgtgagat ttgtcgtgaa acaggcaatg
    19621 agcatgttca attatttgct aaaatcgaaa accaacaagg tattgataac cttgatgaaa
    19681 tcatcgaagc tgcagatggt atcatgattg ctcgtggtga tatggggatt gaggtgccat
    19741 ttgaaatggt tccagtcttc caaaaaatga ttatcaccaa ggtaaatgca gcaggtaaag
    19801 cagtcatcac cgcaactaac atgcttgaaa caatgactga aaaaccacgt gcaactcgtt
    19861 cagaggtatc tgacgttttc aacgcggtta ttgacggtac agatgcgaca atgctttctg
    19921 gtgaatcagc aaatggtaaa taccctgttg aagcagttcg tacaatggct acaattgata
    19981 aaaatgcaca aactcttctt aatgagtatg gtcgtttaga ttcatctgcc ttcccacgta
    20041 ccaataaaac tgacgtgatt gcttcagctg ttaaagatgc aacacactca atggatatca
    20101 agcttgttgt gaccatcact gaaacaggaa acacagctcg tgccatttct aagttccgtc
    20161 ctgatgctga catcttggct gtgacctttg atgaaaaggt tcaacgtgcc ttgatgatta
    20221 actggggtgt gattccagtg cttgctgaaa gaccagcatc aacagatgat atgtttgagg
    20281 tagcagagcg tgtagctctt gagactggtt tggtgcaatc aggagataat atcgttattg
    20341 ttgcaggtgt gccagttggt acaggtggta caaatacaat gcgtgttcgc actgtaaaat
    20401 aatagctttc cataagcttt agctattttg ctctatcaga taatttaagg caaacaatga
    20461 tacttaaaaa ttgtttgctt tttttattag tcatatcatg ttataatgag actatagact
    20521 aggagttatt atggtaaagc gagattttat aagaaatata ttgttgttat tgattcttat
    20581 tgtgggagct gtccttctta gaatatttgt tttttcgacc tatcgagtca cgtcagaggc
    20641 ttcaaatgcc tatttgaata agggcgattt aatcaccatt aagaaaaata ttgagcctaa
    20701 atataaggat tttgtggttt atacggttga caaaaaggat tatgtgagcc gggttgtagc
    20761 agtagcaggt gatcgtgtta cctatatgga cgatattttt tacctgaaca atatggttga
    20821 atcccaatcc taccttgaga gtatgaaggc aaagtatctc aatcatgccc ctattggtac
    20881 gctttatacg gaggatttta cgatttcgac ggttacttct ggaaaatacg atagcattcc
    20941 caaggggaaa taccttttgc taaatgataa cagaaaaaac catcatgata gccgtcagtt
    21001 tggcttaatt gacgtgtcac aaattaaggg attagtaaca tttagagtgc ttcctttgaa
    21061 agactttgga tttgtagagg tagagtagct ttaaggctgc tctattttgt ttctcaaaat
    21121 atgactatac caattttctt gttgacaaga tttttctgaa gttatatact ctaaatataa
    21181 cgttttagtc ggtttatatc tgactatacc aattatattg atcattaaag aaagtagtaa
    21241 gctagcttac tgaggtgtta agttatgtgt ggaattgttg gagttgtagg tagtcgtaat
    21301 gcgactgaca tcttgatgca gggattggaa aaattagagt atcgtggtta tgattcagct
    21361 ggtatttttg tgtcagatgg caggacgtcc aatttggtaa aatctgttgg acgcattgca
    21421 gatttacgct ctaagattgg cattgatgtt gttggaacga ccggtattgg tcatacacgt
    21481 tgggcaacgc atggtcaagc aacagaggaa aatgctcacc ctcatacctc tcagacaggt
    21541 cgctttgttc ttgttcataa tggtgtgatt gaaaattacc tccagatgaa ggagcagtac
    21601 cttgctggac acacgtttaa aggacaaaca gacaccgaaa ttgcagttca tttgattgga
    21661 gcatttgttg aagaaggctg ttcagtctta gaggctttta aaaaggcttt atcaatcatt
    21721 gaaggctcct atgcctttgc tttgattgat acagaggata tggatacgat ctatgtcgct
    21781 aagaataaat ccccattgct gattggcctt ggtgagggct ataacatggt ttgttcagac
    21841 gctatggcca tgattcgtga aaccagcgaa tttatggaaa tccatgacaa ggagctggtt
    21901 atcctgacaa aggattcagc aagggtgaca gattatgctg gcaatccgat tgatcgtcag
    21961 tcatatacag cagagcttga tctttcagat attggcaagg ggacctatcc attttatatg
    22021 ctaaaggaaa ttgacgagca gccaacagtg atgcgtcgct tgatttcaac ctatgcagac
    22081 gccaagggac agatgatgat tgatccagct atcataaggt ctgtccaaga ggctgatcgt
    22141 atctatattc ttgcagctgg gacctcttat catgctggct ttgcttctaa gtcaatgctg
    22201 gagcatttga ctgatacacc tgttgaatta ggggttgctt ctgagtgggg ctacaatatg
    22261 ccgctattga gcaaaaagcc aatgtttatc ctcttgagcc agtccggtga gacagcagat
    22321 agccgtcagg ttttggtcaa ggcaaatgag atggggattc caagcctaac agtgacaaat
    22381 gttcctggct caaccctatc acgtgaagca acctacacta tgctgctcca tgcaggtcca
    22441 gaaattgcag ttgcatcaac taaagcctac acagcacagg tcgctgcact tgcctttcta
    22501 gctaaggcag ttggtgaggc taatggcaag aaggaagcta ttagctttga tttggttcat
    22561 gaattgtcat tggtcgctca gtctattgag gccaccttat ctgacaagga gctgattgct
    22621 gagaaggtgc agaccttatt ggcaacaaca cgcaatgcgt tttacattgg tcgtggcaat
    22681 gattattatg ttgctatgga ggctgcacta aaattaaaag aaatttcata cattcagtgt
    22741 gaagggtttg cagctggtga gctaaagcat gggactattt cactgattga ggatggcaca
    22801 cctgttattg gacttatttc ttcaagtgag ctggttgctg cacatacacg tggcaatatc
    22861 caagaggtgg ctgcacgtgg cgctcatgtg ttgacagttg ttgaggaggg cttagagcgt
    22921 gagggagatg acattattat taataaggtg cacccattct tagcgccgat tgctatggtt
    22981 attccgactc aattaattgc ttactatgct tccttgcagc gtggtttaga tgtagataag
    23041 cctcgtaatt tagccaaggc tgttacagtt gagtaatagt tgcctgctta aaatgaggca
    23101 gcagggtcct gaagcctatt tgaaacgagc ttgacatgat gttatgtcag gctcgttttt
    23161 tagtgcttgc ctggtcttat gataacgtat tcatcttgtc aaataagcat ttctgaagta
    23221 aaatattaac gttaagacta agaagcttag gagagtaaga tgacgttacc aaattgttta
    23281 caatgcgatt cagaatatgt ttatgaggac gggcatttgc tcatttgtcc gatgtgttcc
    23341 tttgaatgga cacgtggtga ggaggagcct gaggaggagg ggcttgtcgt tttagatagt
    23401 aatggaacta gattagctga tggagacact gttacgatca ttaaggacct gaaggtcaag
    23461 ggagcgccga aggatctcaa gcagggaact cgtgttaagc atattcgtct tgttgaaggt
    23521 gatcacaata ttgattgtaa gattgatggc tttggtgcaa tgaagctaaa atcagaattc
    23581 gtcaagaaga tttaataaca ataagcaacc agatgactgg ttgtattttt atagaaaagt
    23641 acttttcaat ccatcagaaa atttggtata atggataaac tatttatatc taggagacaa
    23701 catgacgtat attatgcagg ttttacccag cttgctggat ggtgccttaa tcactttaca
    23761 ggttttcttt attgtaattg tattatccat tcccttaggg gctcttttag cttttttgat
    23821 gagggttgac tttaagccct tgcagtggct attgacgctc tatatttggg tcatgagggg
    23881 aacaccctta ttgttacagc tcatcttttt ttattatgtt ttgccaagtg tgggtgttac
    23941 ctttgatcgt atgccggcag cgattttggc ttttacctta aactatgctg cttattttgc
    24001 cgagattttt cgtggcggga tagagactat tccaaatggg caatatgagg ctgcaaaggt
    24061 gctgaagctt agtccggtac aaactgttcg ctatgttatc ttgcctcagg tgttcaagat
    24121 tgttttacca agtgttttca atgaggtgat taacttagtt aaggattctt ccttggtata
    24181 tgtgttagga gtaggggatt tgctattagc aagcaagact gcggcaaata gagatgcaac
    24241 cttagcaccg atgtttattg caggtttgat ttatttgctc ttaattggtt tggtcaccat
    24301 tttatcgaag caggttgaaa aaagatttaa ttattatcag taagggggtc atatgttaga
    24361 actgaacaat atttcaaagc gatttggtca caagcagatc tttgatggct ttcatttgac
    24421 cgttgaagat ggtgaggttt tatctttggt agggccatct ggtggtggca agactactct
    24481 gctccgaatg ctggctggct tagagcctat tgattcggga aatattagct ataatggcga
    24541 gtctgttcct attgatcatt tagaaaaaag aagcctgctt ggttttgttt ttcaggattt
    24601 ccaattgttt ccacatttga cggtgctgga taatctcatc ttgtctccta ccattaccat
    24661 ggctatgcca aggcctgatg caaagcaaaa ggctatggag ctgctggagc gcctaggtct
    24721 caaagagcat gcagctgctt atccttatgc gctatctggt gggcaaaagc aaagagttgc
    24781 cttggctaga gcgatgatga ttgacccaca gattgtaggc tatgatgagc cgacaagtgc
    24841 cttagactct gaattacgtc aggaggttga gaaattgatt ttgcaaaatc gtgagatggg
    24901 cattacccag attgttgtca cccatgattt gcagtttgct cagaccattt ctgatcgtat
    24961 catcaagatc aatcctaaat agaagaagag gtagtgctat gacgttaaaa aagacccttc
    25021 tagtagccct atttgctgct acagctacgc ttttagtagc ttgtggcgct agtaataaac
    25081 agactagctc agatgcttgg gattcctaca agcagaaaaa gacgattacg cttggctttg
    25141 ataatacttt tgtgccaatg ggctataagg acgagtcagg aaaaaatacc ggctttgata
    25201 ttgagctagc aaaggctgtt tttgaccaat atggtatcaa tgttaagtat caagccatta
    25261 actgggatct caaagaaact gagttgaaca atggtaaaat tgacctgatt tggaatggct
    25321 attctgtgac aaaagagcgc caagctaagg tggcctttac agagccttat atgaaaaatg
    25381 agcaagtctt agtgacgcaa aaatcatcgc aaataagctc atttgctgat atgaaaaata
    25441 agaccttagg tgcccagtct ggctcatctg gctatgatgc ctttacgagt catcctaagg
    25501 tgctaaagga tcttgtcaag ggaaatgacg ctacccaata tgaaaccttt acacaagcct
    25561 ttatcgattt aaaaaacaag cgtattgatg gccttttgat tgatagggtt tatgccaatt
    25621 attaccttca gcaagaaggt gagctagacc gctataacat tatcgcgagt gagtttgaag
    25681 gtgaggattt tgcagttggt gtccgaaaag cggataaaac cctacaaaaa aagattacac
    25741 aagccttaaa atcgctttat caggacggta ccttccaaaa aatctctaaa aaatggtttg
    25801 gtgaagatgt cgcaacagtt cagttgaaat cataagacgc aagcaagacc taatcagctc
    25861 agaggggttg agactagata catttaaaag acttaccttc taaaggcaag tctttttata
    25921 cggcttatta ttagctgata cgcttgatat gatagtgttt tttaattgct atggagtttg
    25981 ttattggtgt gatttgatga tatatcaggt gccaagcttc gtgtcgtctc cagatactgg
    26041 tatgctgatt gccctgtagc tgataggtga ctagcttggt gttgtggctg atggattgca
    26101 tacaaaaggc ttcaagctga ttggaagaag aacgctgctg ctctaaaaat tgcttggcat
    26161 tgtaagcttg tccatcgcga tcaataaagg taaaggtctt ggcaatgagc tcttgataat
    26221 ctgggatttg acttagcatg attttctcgt ttttgtagag ctttttgtaa acatattcac
    26281 agttgtcatc tttaggaagc tttgcaggct caacatgaat atcaatatca taaacagcaa
    26341 attgctcact caagagctgt tcgacctgct cggttatggc gtgactttca taaacagaaa
    26401 ggtcagggtg catctcaagg acaatatcta aatagacatt gcttccgtaa gtgcggccgc
    26461 gctgtgattt gacagcaatg attttgggaa ttttcaatat ggccttttca tatgctttga
    26521 gctgcgtgct gtcaaagcca tctgataagc taaaggcgct tgccataaaa atatcaaagg
    26581 ctgtttttag aatgaaaaag gtaatgataa gggcagccag cctatcaata ataggtagct
    26641 ttaaggaagc ggcgataata gcaatagagg ttccaataga ggtcacagca tcagaaagat
    26701 tatctttaga ggctgcaacc aaggcactgg atcttacctt ttttgataac gctttattaa
    26761 aagcatatac tccaagcatc acaagggctg aagcgatccc aacaatagca cctaatggat
    26821 cgatagcaga ctgcttacca ctaatcatct gttgaatagt ttgcaggaga acctgaaagc
    26881 caacaatgaa catgataaag gaggttatta agcttgaaag gtcttcgatt ttccagtggc
    26941 caaagcggtg attggcgtct gctggctggc tggccagatg aagtccgatg agcagagtga
    27001 cattaccaac gatatcagac aggttgttga agccatcggc aatcaaggag ctggcattta
    27061 aaagatagcc agcaagaagc tttgtgatgc taagggccaa ataggtaaca atgctaacaa
    27121 tgggccctct ttttgctaac cgaaggtttt ctactggatt gtttggcata aaaactcctt
    27181 tgtaactgat gctttcatta tatcataaaa gctaagacaa gctaaaagcc tagagctatc
    27241 ctaaataggg tattccaggc ttttcgatag cttatttggt gctttggcgc ttaaaatatg
    27301 cccttgtctc aaaaatgaca acaggagata aggctagtag ggcgataaga tttggcagag
    27361 ccatcaggcc attgacaata tctgccagta tccaaatcaa ctccagctta agaaagccac
    27421 caagtcctac catgataaca aagatcaggc gaaaatagct gaggtgtgtc gtgccaaata
    27481 aaaagataaa gcagcgctca ccataatagc tccagccgag aatagtcgta aaagcaaaaa
    27541 gaacaagcga cagggtcaag gcataggtgc ccatatgccc aaagatagaa gcaaaggcag
    27601 actgtgttaa gggtgctccc tctagtgcgc tagtccactg accagttacc aaaatggcca
    27661 gaccagtcag agtgcagatg atgatcgtgt caataaaggt tccggtcata gaaatcaggc
    27721 cctgttctac tggctccttg gttttagcgg cagcagcagc gatcggagca gagcctagtc
    27781 ctgattcgtt agaaaaaacc ccacgtgcaa tacccttttg aatggcgtcc ttaaccaagc
    27841 ttccggcaaa gccccctata gctgctgtag gggtaatagc ggacttaaag ataaggacaa
    27901 gcataggaag aagcttagta tagtgaacag caataaccgt taagcttgct ccaatataaa
    27961 agatagccat gaaaggaacg actgtttcag ccaccttggc aatagcttga atgcctccaa
    28021 aaataatcat ggccacaaca gcagctagca agacactgat taatggcgaa gagatcccaa
    28081 ggctatggtg tagggatgag gtaatcgcat tgacctgagc aaatgtcccg attccaaaca
    28141 aagccactaa aataccagag acagcaaata agttggctag aggcctccat ttttgcccca
    28201 taccatttaa aatgtagtac ataggtccgc ctgaaatctg accattagcg tccttagtac
    28261 ggtatttaat ggctaaaacg ccctcggaat atttggttgc cataccaaag aaggcagcaa
    28321 cccacatcca aaaaagtgcc ccaggtccac cagactttat agcggttgcg acaccaacaa
    28381 tattaccagt accaactgta gcagctaggg ctgttgctag agcagcaaat gatgaaatat
    28441 ctccttgccc ctcattctta gcaaaaatga gcctaaaggc cttaggcaac ttgatgactt
    28501 ggagaaggct aagtctgctg gtgaggtaaa tgccagtacc aagcagcagt agcaacaagg
    28561 gtgctcccca aaccaaatcg tctatccatt ttgcagcagc tatcatgctt aattcctcaa
    28621 ctctcttaac caatgctgcc aaaagaaaaa gccacccctg cggatagcct ctgaagcata
    28681 tgacaaaaca gcaagcacaa aaaatgctaa ggaagcatga tcatacggct tgatatttta
    28741 tcttctgtcc ttttgcctga gagattgagc agtcttgcct tgccccttcg gcgcctaata
    28801 ggtctctcca gaagcccgtc cgtcaagcag tcccgtccaa cacctgaaca cctgagagta
    28861 taactccttc ggcgaaatcc attcttctcc tgcatgacat cattcggttt attaaattat
    28921 gtctatgata cccaaaaagc ctagtgatgt caacaagcaa tttaactgat ggctaactcc
    28981 ttgtttttat ggtaacatca ttgtcctctt ttttcttttt gactgaaaca tgatataatc
    29041 gtaaggttaa taaaagtcac ttattagacg atatgaggag aaagcatgaa tcctttatta
    29101 gatggaatga atgataaaca agcagaggca gttcaaacga ctgagggccc cttgttaatt
    29161 atggctggtg ccggttctgg gaaaacgagg gtattaaccc accgcattgc ctacttgatt
    29221 gatgaaaagt atgttaatcc ctggaatatt ttggcgatta cctttactaa taaggctgcg
    29281 cgtgagatgc gagaaagggc attggcctta agcccagcca ccaaggatac cttgattgcg
    29341 acctttcact caatgtgtgt tcgtatttta cgccgtgagg cagatcatat tggctacaat
    29401 cggaatttca cgattgttga tccaggagaa cagcggacct taatgaagag aatagtaaaa
    29461 gctctaaatc tggatcctaa gaaatggagc gagcggtcga ttttagccac catttcaaat
    29521 gctaaaaatg atctcttaga tgaaagagcc tatgagctag gagcctctga tttgtatagc
    29581 cagacagttg cccgctgcta caaggcctat caggaggagc tcagacgaag tgaggctatg
    29641 gattttgatg atttgattat gatgacctta cgcctatttg atcaaaatcc tgacgttcta
    29701 gcctattatc agcagcgtta tcaatatata catgtcgatg aataccaaga cacaaaccac
    29761 gctcaatatc agctagtgac tcttttagcc tcacgcttta aaaatatttg tgttgtcggt
    29821 gatgcagacc agtccattta tggctggcgt ggtgctgata tgcaaaatat tttagatttt
    29881 gaaaaggatt accctgatgc aagggtggtt ttgctggaag aaaattatcg ctccaccaag
    29941 aaaatccttc aggcagctaa cgaggtgatt cagcataatc gtcatcgtcg tccgaaaaaa
    30001 ttgtggactc aaaacgcaga cggtgagcag attgtttatt atagggcaaa tgatgagcgt
    30061 gacgaggctg tttttgttgc ctcaaccatc agcaatatgt gtctagagct aggaaagagc
    30121 tttaaagact ttgctgtttt atatcgtacc aatgctcagt cccgtacgat tgaagaagcc
    30181 ttgttaaaat caaatattcc ctacacgatg gtcggaggaa ccaaattcta cagcagaaag
    30241 gaaattcgtg atgtgattgc ctatttgact gtggttgcta atccgtcaga taatctctcc
    30301 tttgaacgaa ttgtgaatga gcctaaacga ggggtagggc caggaaccct agataagctc
    30361 cgccaatttg cttatgggca aggacagtca ttgttagagg ccgcttcaag ccttgagcaa
    30421 tcaccgctaa aaggaaaggc tgcccaagcc atgctggcct tagcgagtct cttaagtgat
    30481 ttgagagctg atttagacca gctgagcatt acagccctgg ccgaggcctt gctggagaaa
    30541 accggctatc tggatatgct gcgcgtccaa aataccttag aaagtcaagc taggattgaa
    30601 aatattgaag aattcctgtc tgttaccaaa agctttgatg acctatcagc acagcagcag
    30661 gagcatgaag caggtattga tcgcttagga agatttctca atgaccttgc tttgattgct
    30721 gatagtgatg atggcaatgc agaaaccgct gaggtaactt tgatgactct gcatgcagct
    30781 aaggggctag aatttcctgt tgtttttctc ataggtatgg aggagggagt ctttccttta
    30841 gcccgagcag ccgaggatca agatgagcta gaagaagaaa ggcgactagc ctatgttggc
    30901 attaccagag ccgaggaatg cttgttttta acgaatgcca atacacgtac cctatttggt
    30961 aaaagcagct ataatcgccc aacaaggttt ttaaaagaga tgtcagagaa ccttttaagc
    31021 ttccaaggct tggcaagacc tgctcatgct tcctttggtg tgacattttc gcagcagggt
    31081 caacgacaat ttggcacagg aatgagtcta tcagaggcta tccagtccag aaaatcaatg
    31141 gcacagcctg ccagagcagc ctcaacatct acaccgctgc cctttggacc gaatgcagct
    31201 acttcaaagc aagccgttga ttggcagatt ggtgatattg cccatcataa aaaatggggt
    31261 gctggaacgg ttttagaggt caagggatct ggtaagacca tggaattaac cattagtttt
    31321 cctgatgtcg gattaaaaaa actccttgcc agcgttgctc ctattgaaaa aaaataaaag
    31381 gtacagctta tgggcaattt gcatagtcac ttggataagg gctttgcaat tgcggtttag
    31441 ttctgcgatt taagaaaaga agtaagcaag gattttatca gttaaccaca taccaagctt
    31501 ttgatggcct tgatgccgga gagagcttgg tattttttta tttttaaaaa aatcacaaaa
    31561 aatgatttat tctgagcata atccttgcaa attaaaatga gaagtgtata atggcaatat
    31621 aaattaaata acaagtggtc acttttgtta atagttgttt taaggtattt gtagcgcttt
    31681 attgttaaac ataaatgtat caaaaaaata actagcaatt ttatatttaa tttatgtagt
    31741 cactttaaag agtgaacaaa gtagttttat tgaattgagg agatttatta tgggaattat
    31801 ttggacatta attgtgggtg cacttatcgg tgctattgcc ggtgcgctta ctaaaaaagg
    31861 cggatcaatg ggctggattg ccaatatcgc tgcaggactt attggatcat acgttggtca
    31921 agctttgttt ggcagctggg gtctaacatt agctggcatg gcacttttcc catcaatcat
    31981 tggtgctgtt atcgttgtta tcattacttc ttttgtacta aataaatcaa actaagggca
    32041 tttctatcat tatagagatg gttgagtagg aaagaggttt ttatgtcgaa atttttaaaa
    32101 attagctata gtctcattgg cttagtccta ttgacggtct ttggtggcgt gatagccata
    32161 actggagatt atattaggct acctattggc tatcaatggc ttcactggga tatgaattgg
    32221 cttcctaaat tcctaaatcc ggccttatat tactattact tttgggcagc tatcgcttta
    32281 tttctaataa cagtgctgat ccttcttgtg attatctttt atccacgcac ctatactgag
    32341 attcagctgg ctaaggataa aggaaccctg cttttgaaag ggtctgctat tgaaggctat
    32401 gtagcagctg ctattaaagc agcagggctt atgtcaagcc caagagttac cgctaagctg
    32461 tacaagcgta aatttaaggt taatgtcagt ggacaattag cttctcgcgt agctgtcact
    32521 gagcagctaa atggcattaa agaaggaatt gagactggtt taacagaatt ctttggtatt
    32581 aatcgacctg tccatttcaa ggtttatgtc aaggatattg ctgatgctaa gcaaaagcat
    32641 agctctaaga gacgtgtaga ataggagatt atcatggcat tttatgaacg gtttaaatac
    32701 cctattattg gtggtctgat agggctgata gctgctgtat tactgatgac ctttgggtta
    32761 tttaaaacac tgctggcaat tattttcatt attttaggag tatatggcgg cctgtatgcc
    32821 aaaaagacag gtattatcga tcaattgatc aaacgtaact aaaggagatt tatcatgact
    32881 gaaacttaca ttaaaaacac aactcataaa gaaccaactt cagctgttcg tggcgaattg
    32941 acctatgatg acaaggtcat tgaaaagatc gttggcttgg ctcttgaaaa cattgatggc
    33001 ctactaggtg ttaatggtgg ctttttggcc aatctaaaag acaagcttgt taatagtgat
    33061 tctgttcgtg atggggttaa tgttgaggtt ggtaaaaaag aggttgctgt tgatttagac
    33121 attgtagcag aataccaaaa gcatgttcca accatttttg atgcgattaa atctgtcgta
    33181 gaaaatgaag tcaagagaat gacagattta gaggtgattg aggttaatgt taaggttgtt
    33241 gacattaaaa ccaaggagca atttgaagct gataaggtca gcctacagga taaggtgact
    33301 gaggtagctc gctcaacctc tgaatttaca agcaagcagg tagacaatgt taaggcatct
    33361 gtaggtgcag gtgtagaaaa ggttcaagag caaactgagc cacgcgttaa gtaagctagg
    33421 ctgtcaaacg atagaaatag aggaaatcat aatgtcagaa gaaaaggtaa atgcaaaatt
    33481 ggagcaagca ggcggtaaaa tcaaagaagc ctttggaaag gtgactggtg ataaatcctt
    33541 agaaaccgaa ggtaaggttg atcaagcagc cagcaaaatc aaagaagtag ctgctgatgc
    33601 taaggacgct gtcaagggct ttgttaaggg ccttaagcaa gataaataag gagttgtaat
    33661 gaaagcaaag gacataaaaa gtacgttgac ctacgatgat aaggtcattg aaaaaatcgt
    33721 tggacatgct ttagagaagg tcagtggctt attagcagtc aatggtggct ttttctcaaa
    33781 tatcaaaaat aacctagtga atagtgactc tgttcgtgat ggggtgtctg ttgaggttgg
    33841 cagcaaggaa gtggctgttg acttagatat tgttgttgaa tatggtaagg atattccagc
    33901 aattgttgag tctatcaagg ctattgtttt tcaaaatgtc gatagcatga cacatttgag
    33961 ggtcgttgaa gtaaatgtga acgttgttga tattagaacc aaagaagagc atgaggctgc
    34021 tagcgtcact gttcaagaca ggctaacaga cgcggcctca gcaacctctc aatttgtagc
    34081 tgagcaagca gacaaggtaa aagaaactgt ctctaaaacc acagataata acgagacagt
    34141 agaataaaac acaacaacta aaactcctgt taatgacata ttgtgggctg gtgtgatgac
    34201 cagctctttt tatcagtgct tgaacaatgt tatgctattg tattctctgt gaaaatgtga
    34261 tttaatggga atggtatcat ttgttaaaaa ggagtaatta tcatgactag taataagaga
    34321 gagattacta attccaagta tcaaaagatt gccatttcag ttgctgaaag gattgccaat
    34381 ggcgaatatg aagtgggaga aaagctaaag tctaggacaa ccattgcttc gacctttaaa
    34441 gtttcgcctg aaactgctag aaagggtctg aatattttag ctgatctgaa gattttgacc
    34501 ttaaagcatg ggagtggcgc cattgtcttg tctaaggaaa aggctattga ttttctgaac
    34561 caatacgaat ccacccattc tatcgctgtc atcaaagaaa atattcgcca taatattcgt
    34621 gagcaggaaa aggcaatgga gcatttaaca gtgcttgtta atgagtttct gatgcaaagc
    34681 caatcaatca gcaagcaata cccgctggca ccttacgaaa ttatttgtag tcaggattca
    34741 gagcattttg gccaatccat tggtgatttg aacatttggc atcaaacggg agcgacgatt
    34801 gtagctattg agcatgatgg ccaattcatt gtttctcccg gtccttacgc tgttatcgaa
    34861 aaaggtgatc atatttactt tgtcggtaat gaggacgtga tttctagaat gaaaaccttt
    34921 tttaatgtta gaaagggtct gtaatcacaa aaaaacacag agctgcttta aggtgatggt
    34981 gatatcacga tgaagtgtct ctgtgttttt gtgttatcag gctaaggctt ctaagtagct
    35041 tatagctctg attgaagccc ctagattact ttttcaaagc caacagtttt caggataata
    35101 gctgtcatgt catcggttgt ttcttgacag tcatgactaa tccagtagct aatcagactt
    35161 tcaatactgg ctagataaac ctcaagcgcg tagtgataag ggatctgata gtgcttggtg
    35221 atgatttctt gaaagccatc aatagtggtc aaaaattgat aaataaaatc cttgagtatt
    35281 tgtgaaaaat tcaaataact ggagttagcc atagcagcaa taaagggaag attatcaatg
    35341 atataagcga gggcttcctt tagaacgagt ctagtatctg taaaaatatg agggtcattt
    35401 aggagctggt ataaatcgtc taaggtgtca tttatgagat gagtcatcat atcatgttta
    35461 tccctgtaat gcagataaaa ggtgcctcta ttgacaccag cttttttggt taagtcagaa
    35521 acggtaatgg tctcaaagct cttttctgtc aaaagactga caagtgcctg cttcaaatag
    35581 gccttggttg gtgtgtgtct tgttgtcatc gactcatctc cttaagtcaa caaatgctgc
    35641 ttatctgttc ttgttaaagt cttgaggaca ttatataata aggctagtat aaaatcaaca
    35701 aggtgttgat ataaaggagg tgacatgatc agtgtcctat attgaaatga ggtcctcttc
    35761 aaagacctac cagattggag aaacaactgt taaggctaat gatgaggtat cctttgagat
    35821 tgaaagaggg gagcttgtga tcattttagg agcctctggt gcaggcaagt ccacagtgct
    35881 taatatttta ggcggcatgg atagcaatga ccaaggtcag gtcataatag acggcaagga
    35941 catctcgacc tatagtaaaa aggcattgac cagctaccgt cgttacgagg ttggctttgt
    36001 ttttcaattt tacaatctgg tgccaaatct gacagcaaag gaaaatgttg agctggcggc
    36061 tgatattgtg gcagatgcac ttgatccgac tactgtctta aatgaggtgg ggctaggagg
    36121 acgtttggag catttcccag cacagctatc aggaggtgag cagcaaaggg tgtctattgc
    36181 tcgtgccttg gctaaaaatc ctaagttgtt gctttgtgat gagccaacag gggctttaga
    36241 ttatcaaacc ggcaagcaaa ttttaagatt gcttcaagat atggcgcacg acaagggcag
    36301 gacagttatt gtggtgacgc ataatactgc tctagcgcct attgctgatc gggtcattta
    36361 tatgcatgac ggtcgtgtga ccaagacagt gcttaataag cagccgcttg atattgatag
    36421 gataacgtat tgagaggtgc ctagatgaaa caaaaaacct tatggaagga tagttttcga
    36481 gcaataaaag ctagtaaggg gcgttttttg tccttgctat ttttaatggc tctaggctcc
    36541 tttgccttgg ttggcttaaa ggtggctggt cccaatatgg aaaaaactgc tagtcactat
    36601 ctagaggagc atcaggttat ggaccttagt atcctaacct cgcatggctt ttctgataga
    36661 gataagcaag aattagcctc tcttaaaaat gcaagactag agtatgcgag ctttgttgat
    36721 ggtgcttttg atcaccagag gaaggctatt aggctttatt ctatgccaca aagcctatct
    36781 caggccagct tggtcaaggg agattaccct agcaaggcta gcgacatttt gctatctgaa
    36841 gctttatcaa gccgctatcg gcttgggcaa ataatcacga taagcctaaa aacaaaggga
    36901 ttgctaaagc atagatccta tcgtgttgtc ggctttgctc attctccaga aatatggtcc
    36961 aaaacaaact taggtgtttc ctcagcaggg gatggtaatc tctatgccta tgcctacctt
    37021 caccctagtg cctttcagca agggcacaat ctcttacgca ttcggtatga tgatttaaga
    37081 gggttgaatg ccttttcaac tcaatacaat gaacgattgc tacaacacca agcagagctt
    37141 gatcagatct tgcaggacaa tggtcaagag cgttatgaag aaatgctcaa tgaccttaat
    37201 cgcagcttga aagatagtaa agttaagctc gaagagcaaa ggactgttct taaggcaagt
    37261 gaagaccagc tggctttgct aagtggtcat gccttagagc aagcgcagac tcagctaaag
    37321 caagggcagg aagagttagc taaaaaagaa gcaagcttgc tagagttagc tgaaaagcaa
    37381 agggcagcga tgatcaagcc aacctatact agctatagtc gctcaacgct gccaggtggt
    37441 gagggttatc aaacctatgc cacctcaaca cagtccatat cgcatgttgg aaatatcttt
    37501 cctgttgttt tgtatttggt tgcggcctta gttactttta caacaatggc tcgctatgtt
    37561 gacgaagaac gaacgaactc aggcttacta aaggcaatag gctattctga ttgggatatt
    37621 accaaaaaat ttctgctata tggtgcctta gctgccttgt tgggcactgg attaggagtt
    37681 ttaggaggga cttatttttt atctcggctc atctcagcta tcctaacaga tgcattgact
    37741 atcggctcta ctcagcttta tttttattgg agctatagtg tggttgcagt gcttttagcc
    37801 ttgttatctg ctgttttgac agcttatatg gtggtgagac gtgagctttt tctcagaccc
    37861 tcacaactgt tgctgcctaa gcctcctagt agcggggcaa ggatttggct ggagcatgtc
    37921 tcctttatct ggcggcgttt atcctttacc tataaggtta cttttcgaaa tatctttcga
    37981 tataagcaaa gaatgctgat gacagtaatt ggagtagcag gttctgttgc gctcttattt
    38041 tccggcttgg gcattcaatc ctcacttgct aatagcctaa gctatcaatt tggcaagctg
    38101 acagcctatg acatgctcgt ggtagaagct ccaacagcag aagctcatga taggcaggag
    38161 ctggcacaat atttgaaggc agatcagatt gctagtaaga aagagattta ttacgctaac
    38221 ttatcactaa agataaaaga cttagacaac aagcaaacag tgtcgttgat ttctagcgat
    38281 cagagcactc tatctcccta ttttagcttg attggtgctg ctgaccgaaa aaagctagac
    38341 cttccaagta ctggagtgct tatctcaaaa aagcttgctg actattatca ggctcatgca
    38401 ggagatcagc ttgagcttga agctagtaac ggtaaacgct atcagttaag agtgagtcag
    38461 gttattgaca tgactgttgg tcattacttg ttcatgtcta aatcttatta tcagcaggta
    38521 tttcgggata tggaggcttc accatcctat ttggtaacaa cagcaaaggc tagtccatct
    38581 gctgtaaagg acgtagctag tcagctctta gcaatgcctg cggttcaggc tgtgtcacaa
    38641 cacagtagta ttgttgctac tgtgacaggg attgtggcgt ctttggatca ggttatgacg
    38701 cttttagtac ttctatcagt tctactagcc ttggtcattt tgtatcattt gaccaatatc
    38761 aatattgctg agagggttag ggaattatca acgataagag tcttgggctt ttatgacaag
    38821 gaggttacct tatacattta ccgggaaacc atgcttttgt ctgctgttgg tattttgatc
    38881 ggtctctggg gtggcagcta tttgcacgcc tatatcatga aggtgattgc taatgattct
    38941 atgagctttg gtaggacagt tgatgcttat gtttacctag tacctgttgg ggctattgtg
    39001 cttttgttga ttgtgcttgg ctatatggtt agctaccggc taagaaagat tgatatgcta
    39061 gaggctctaa agtctgttga ttagggtaaa atagtacttg aaaatcgctt aataatatgc
    39121 tagtattaaa atactataat ttaatagaag gatactttta tggaagcgat gatagctgcc
    39181 tatttggctg atcatagaga aaagatacca cttggtcagg ttgttgattg ctttaagggg
    39241 aaggctgttt ctcgtaaggc tgaggctggt gaatttggtt tgattaatct gtctgatatg
    39301 ggacagctag gaattgacta tcatcaggtt agagcctttc atatggatag acgacaacta
    39361 ttgcgctata tcttagagga tggagatgtc ttgattgcct caaaggggac tgttcagaag
    39421 gtttgtgttt ttcataagca agaaagggaa atggtagcgt cctctaatat cacagtgctg
    39481 cgtcctcaga gggttttgcg aggctattat attaagttct ttttggagtc tgctattggt
    39541 caagccttgt taaaggcggc ggatcatgga aaggacgtga ttaacctatc gaccaaggct
    39601 ttacttgata tccctgtacc agtgattcct ttggttaagc aggattattt gattaatcaa
    39661 tatttgcgag gcctgcatga ctatcaacgg aaagtaaaca gagctgagca ggagtggcag
    39721 tttattcaaa atgaaattca aaaaggcttg ggctagaggt aaaatgtgag cttaattgaa
    39781 cgaacaataa aaatgctatt agcaacgatg gctgcaatct ttcttgcctc tcagctacag
    39841 ctgtcttatg ccatatcagc gggaattatt gccctgttag gtgtgctaga cactagaaaa
    39901 tctagcttaa ttgttgctag aaagcgtctg ctgtcttttt tcttagcctt tgctgtggcg
    39961 gttagtctat ttgccttatt tggctttggt ctgctttcca ttggcttgta tctagcgcta
    40021 accattcctt tgctttatca gctgaaaata gaggcaggtc ttgttcctat cactgtcttg
    40081 gtgactcacc tgatgtctga gcagcgtatt gatttgtcaa ttctttttaa tgagctgttg
    40141 ctgtttttga ttgggacggg tcttgccctt cttgttaacg ggtatatggg gtctcaggag
    40201 catcgcctac gcttgtacca ccaaaagata gaagatagct taaaggctat cttgtaccgt
    40261 tttgaatcct ttttgttaga aggccaagga caaaacgagg gacagatgat taaggaatta
    40321 gagcttagct tagatgaggc gctaaagctg gtttatcgcg aaaggcacaa taccctcttt
    40381 tatcatacca attatcaggt gcattatttt gagatgagac gtcatcaaaa tagattgttg
    40441 gcgcaaatgg ccttaaatgt cactcagcta acatctcaaa gcagagaaag tctcctgctc
    40501 tcccatcttt ttcatgagac agctcgtcag ctgagtgaga agaattctgc tttgacattg
    40561 attgatgata ttgagcaatt gcttgaggtc tttaggcaaa gagagctgcc tcagactaga
    40621 gaggaatttg aaagacgggc gattctgttt cagctgttgc aggatttgga gcgctttatt
    40681 ctactgaagg tagaatttta tcgtgattac aaggaagagc aggcatagta gctgcttgct
    40741 gctgtgatta agagtctgga aaaatcattt tctaggcttt tttgctataa tcccgacttt
    40801 atcacttgtt ttagtccaca cc
//
LOCUS       DARYUW010000013        39075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYUW010000013 DARYUW010000000
VERSION     DARYUW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            110..637
                     /locus_tag="TVW11_000584"
     CDS             110..637
                     /locus_tag="TVW11_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1364711.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TVW11_000585"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TVW11_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1364712.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TVW11_000586"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TVW11_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1364713.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TVW11_000587"
     CDS             2207..2839
                     /locus_tag="TVW11_000587"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1364714.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TVW11_000588"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TVW11_000588"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1364715.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TVW11_000589"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TVW11_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1364716.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TVW11_000590"
     CDS             3914..4657
                     /locus_tag="TVW11_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1364717.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TVW11_000591"
     CDS             4767..5867
                     /locus_tag="TVW11_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1364718.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TVW11_000592"
     CDS             6223..6930
                     /locus_tag="TVW11_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1364719.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TVW11_000593"
     CDS             7071..7787
                     /locus_tag="TVW11_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1364720.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TVW11_000594"
     CDS             8009..8854
                     /locus_tag="TVW11_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1364721.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TVW11_000595"
     CDS             9226..10071
                     /locus_tag="TVW11_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1364722.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TVW11_000596"
     CDS             10149..11519
                     /locus_tag="TVW11_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1364723.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TVW11_000597"
     CDS             11512..12576
                     /locus_tag="TVW11_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1364724.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TVW11_000598"
     CDS             12577..13269
                     /locus_tag="TVW11_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364725.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVW11_000599"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVW11_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1364726.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TVW11_000600"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TVW11_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1364727.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TVW11_000601"
     CDS             complement(16695..17369)
                     /locus_tag="TVW11_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1364728.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TVW11_000602"
     CDS             complement(17379..18755)
                     /locus_tag="TVW11_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1364729.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TVW11_000603"
     CDS             complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TVW11_000603"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1364730.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            20127..20684
                     /locus_tag="TVW11_000604"
     CDS             20127..20684
                     /locus_tag="TVW11_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1364731.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20721..21614
                     /gene="htpX"
                     /locus_tag="TVW11_000605"
     CDS             20721..21614
                     /gene="htpX"
                     /locus_tag="TVW11_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1364732.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21902..22435
                     /locus_tag="TVW11_000606"
     CDS             21902..22435
                     /locus_tag="TVW11_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1364733.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22620..23306
                     /gene="covR"
                     /locus_tag="TVW11_000607"
                     /gene_synonym="csrR"
     CDS             22620..23306
                     /gene="covR"
                     /locus_tag="TVW11_000607"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1364734.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23310..24800
                     /locus_tag="TVW11_000608"
     CDS             23310..24800
                     /locus_tag="TVW11_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1364735.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24991..25485
                     /gene="nrdR"
                     /locus_tag="TVW11_000609"
     CDS             24991..25485
                     /gene="nrdR"
                     /locus_tag="TVW11_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1364736.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25469..26632
                     /locus_tag="TVW11_000610"
     CDS             25469..26632
                     /locus_tag="TVW11_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1364737.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26633..27541
                     /gene="dnaI"
                     /locus_tag="TVW11_000611"
     CDS             26633..27541
                     /gene="dnaI"
                     /locus_tag="TVW11_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1364738.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27591..28901
                     /gene="der"
                     /locus_tag="TVW11_000612"
     CDS             27591..28901
                     /gene="der"
                     /locus_tag="TVW11_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1364739.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29242..32334
                     /locus_tag="TVW11_000613"
     CDS             29242..32334
                     /locus_tag="TVW11_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1364740.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32538..33131
                     /locus_tag="TVW11_000614"
     CDS             32538..33131
                     /locus_tag="TVW11_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364741.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33175..34506
                     /locus_tag="TVW11_000615"
     CDS             33175..34506
                     /locus_tag="TVW11_000615"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1364742.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34554..35036
                     /locus_tag="TVW11_000616"
     CDS             34554..35036
                     /locus_tag="TVW11_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364743.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35145..36719
                     /gene="mltG"
                     /locus_tag="TVW11_000617"
     CDS             35145..36719
                     /gene="mltG"
                     /locus_tag="TVW11_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1364744.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36792..37274
                     /gene="greA"
                     /locus_tag="TVW11_000618"
     CDS             36792..37274
                     /gene="greA"
                     /locus_tag="TVW11_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1364745.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TVW11_000619"
     CDS             complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TVW11_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1364746.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38518..38796)
                     /locus_tag="TVW11_000620"
     CDS             complement(38518..38796)
                     /locus_tag="TVW11_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1364747.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
BASE COUNT        11290 a         7214 c         9221 g        11350 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt ttattaggaa taccggcttt tcgagggtac
    19321 ttgtttggcg tttccttttt cttttcgaca agagtgatat agcggccatc tccattagga
    19381 agttggtagg gctggtgatc aagcacctta gcaaaaagta gctgaagtgc ctttttagct
    19441 tcttctaatt cttggtccgc tgcttgtgcc tttaaagcaa tcagttttcc cttgattttt
    19501 aaaaaaggaa tggtcaactc agacagaatc tgcatgcggg caacagctct agcagttacc
    19561 aaatcaaatt ggccacgaaa ttgcttgtct tgtccaaaat cctctgccct accatgatag
    19621 aaatgtactc cctctaatcc tagctcttta gcaaggagct gaagaaaatg tatgcgctta
    19681 ttgagagaat caataatggt aacatcaagc tttggaaaca taattttcat aggaatgctt
    19741 gggaagcctg ctccagcccc aatatctaac agcctgagag gctcatttgg aatatatccc
    19801 tgtaaaagcg gagcaacaga gtcataaaag tgcttgagat agacttcatt ttcttcagtg
    19861 atggctgtta agttgatctt acggttccaa tcaaccaaaa gcttaaaata agtgtcgaat
    19921 tgttcttttt gatgatttgt cagagcaaat cctgcttgct ccaggacaag gtaaaaggct
    19981 tggggtgtca tatatatcct ctgtttttaa ttaattgcta ctattttagc ataaaatagc
    20041 agaaaactgc tgaaaagtcc cttcaatact tgctattaaa ctgaaaattg ctataattga
    20101 gacacaaaga ttaaaggaga attacaatgc caatgttttt agtaatagta gcccttatcg
    20161 gtgtgctggt tgtttggctg atggttagct ataatggcct ggttaaagct cgtatgcata
    20221 caaaagaagc ttggagtcag attgacgtgc agctaaagcg tcgcaatgac ttgattccaa
    20281 accttgttga gacggtcaaa ggctatgcta atcatgaaga gaaaacctta gaaaagatta
    20341 ctagtcttag atcacgtgtg gctgatgcta ctacaccgca ggccacaatg gcagcctcca
    20401 atgaattgag caagcaggtc actagcctct ttgcagttgc agagagctat ccagacttaa
    20461 aggccaatag taatttccta aaattgcaag aggaattaac caatacagaa aataaaattt
    20521 cttattcgcg tcaattattt aatacaacaa catcgcatta taaccttaag ctagaaagct
    20581 ttccgagcaa tcttgtggct aaattgtttg gcttcaagcc aagtgagttt ttacaggttc
    20641 ctgaagctga aaaagaggtt ccaaaggtag actttaccgt ctagtctaat gcggctaatc
    20701 aaggtcagaa gaggacatca atgctttatc aacaaatttc acaaaataaa cgacgaactg
    20761 ttatcctgct ttttgccttt tttgtcttac tggtagtgat tggcgctgct gctgggtatt
    20821 tactggctga cagctaccag ctgggggctg cttttgctct gattattggt gctatttatg
    20881 cctttagcat gatttttcag tcaaccagcc tcgttatggg aatgaataag gctaaggaaa
    20941 tcacagtaaa cgatgctcct gatttctttc atattgttga ggatatggct ctggttgctc
    21001 agattccaat gccaagagta tttatcattg atgatccctc actaaacgcc tttgccacag
    21061 gctccagccc tcaaaatgca gctgttgcgg caaccactgg tctactaaag gtgatgaatc
    21121 gtgaggagtt agaagcagtg attgggcatg aagtcagcca tattcgtaat tatgatattc
    21181 ggatatccac tattgcagtt gctttagcta gtgctgtcac actgatttcc agcattgggg
    21241 ggcgtatgat gtggtatagc ggtggcagga gacgtgataa cgatcgcaac gataatggct
    21301 ttggcgctat tatgctgatt ttctcaatct tgtcactgat cttggctcct cttgcggcct
    21361 ctctggttca attagccatt tctcgtcaaa gagagtatct ggcagatgcc agctctgtcg
    21421 cgttaaccag aaatccagag ggcatgatta gggctctaca aaagctaagc aattcacagc
    21481 ctatgactca tccagtagat gatgctagcg cagccttata catcaatgag cctagaaaaa
    21541 aagaaaagct tagcgcttta tttagtaccc atccgccgat tgaagataga attgaacgct
    21601 tgaagcatat gtgagagctt gagactagct cagctctcat ttttactagc cataatgttc
    21661 agaaaacatc attaattaat tgttttgacc cggacatttt ttaagacttt tatggaaatt
    21721 tgggctattt tcataggggt tttatggtta aacatttgat tgttggcttg tcaatactta
    21781 tttgtatcca gacttaatgt taaaaaaagt tatgaatttg tcataaagct attgacaaat
    21841 tcttgatatc atagtaaaaa tagattagag ttttattagg aagtgtttta taggagaaag
    21901 catgttatct gtttcagata ttagaaagcg accggaaggc attcgctttg agagagagta
    21961 cgatgttaag gaagcgctgc ttatacgtga tccgcaggtt atagatatta ataacgtcag
    22021 agcttcgggg agagctcagt ttgatgacgg cttgtatcta ttagagtatc agctgggcta
    22081 tcagattacc ctgccctcga gccgttccat ggcgcctgtt gtcttagatg agatgcagac
    22141 ggttcaggag ctgtttatcg aggaagcaga tgtggcaagt aagcaggaaa tggttgatga
    22201 aaaccttgtc ttagtcttat cagaggatca gcttgacctt gaagagagta ttattgacaa
    22261 tattttgttg gcgattccct tgcaggtatt gacagaggct gaaaaggagt cacaaatctt
    22321 gccgacaggg gaggattggg cagtcttaac tgaggagcaa taccaggccc agcagaagga
    22381 aaaagcaaaa gacaacagtc cttttgcggg cttacagggt ctttttgatg agtaaaaata
    22441 aaaattaaag atgtctgtat tttttatttg aaaaaagaac agttgtctgg tatactttat
    22501 aaatatacgg catattagtc attttgatga ctaaatagca atacttgatt aatacaaaat
    22561 ggatgaatct tgtacatagc tgataagggg ctgtgataca ggaagtaagg attggtgtaa
    22621 tgacaaagaa aattttaatt atcgaagatg aaaagaatct tgcaagattt gtttcgcttg
    22681 agctacagca tgagggttac gaggtgaccg tcgaggttaa tggtcgtgag ggcttggaga
    22741 cagccctaga gaaggacttt gacttaatcc ttcttgattt gatgcttcct gagatggacg
    22801 gatttgaagt gacacgtcga ttgcaaacag aaaaaacgac ttacatcatg atgatgactg
    22861 cgcgtgactc tattatggac gttgtagctg gcttggatcg tggtgctgac gattacatcg
    22921 tgaagccatt tgccattgag gaattgctgg cgcgtattcg tgctatcttc cgtcgtcagg
    22981 acattgagtc agagaaaaag actcctagtc aaggcgttta ccgcgactta gtcttaaacc
    23041 ctcaaaaccg ctctgtcaat cgcggtgatg acgagatttc actgactaag cgtgaatatg
    23101 acctgcttaa tattttgatg acaaacatga atcgtgtcat gactcgtgag gagctcttgt
    23161 ctaacgtttg gaaatatgac gaggctgttg aaactaacgt tgttgatgtt tatattcgtt
    23221 accttcgtgg gaagatcgat atccctggga aagagtctta cattcaaact gttcgtggaa
    23281 tgggttatgt gattcgcgag aaataattga tggcaaagca gaaaaaatat aagaaaacgt
    23341 taccaaaacg tttatcgaat cttttgttcg ttctcttctt ttgcattttc tctgccttta
    23401 ccctactcgc ttatatttca acaaactact ttttgttgaa acgagaaaag caaactattt
    23461 ttcaggctgt taacattgtt agagttcgtc tctctgaggt ggactctaat tttacgttag
    23521 agaatttagc agaggttctc tataaaaatg acagaacgca tttaaagatt gatgacgcaa
    23581 atggtagtcg tattatcaga agtgaacgaa atatcaccaa cacgctcaat gccaatgagg
    23641 atatctatgt ctacaatgtt gataagcaaa tgatcttcac aacagatgac gaagaggcct
    23701 cgccaggctt aaatggaact attggtaagg taaccaagga ccacattgag gagcaataca
    23761 agggcttttc aatgactcag aaggtctact ctaataagac agggaagttt gtaggctatg
    23821 ttcaggtttt ccatgacttg gaaaactact acatgatcag agcacgcctc ttcttttggc
    23881 ttttggtggt tgagctcttt ggggttggtc tggcgtattt cattatctta attgtcacac
    23941 gcaacttctt gaagcctctg aacaatcttc atgatgtgat gcggacaatt tccaaaaatc
    24001 cagataatct gatgctgcgc tcgggtattt cctcgggtga tgaaattgag gaattgtccg
    24061 ttatttttga taaaatgctt gataagattg agacgcatac acgattgcaa tcaagattta
    24121 ttagtgacgt cagtcatgag ctgcgcacgc cagttgccat tatcaagggg catattggat
    24181 tattgcagcg ctggggcaag gacgatagtg ctattttaga tgaaagcctc actgcagctg
    24241 cgcaagaggt tgaccgaatg gctattatga tcaatgacat gcttgatatg atccgagtac
    24301 aggggtcctt tgaagggcat caaaatgata caactgtttt agagagctct attgagaccg
    24361 ttgttggtaa ttttagggtc ctgcgtgagg attttgattt tacctggtac tctgaaaatc
    24421 aaagaaccct agccaagatt tataaaaatc attttgagca ggctctgatg attttgatag
    24481 ataatgcggt caagtattct aggaaggaaa agaaaatcgt catagaatta gcggttaatg
    24541 ctagcaatga agctgtggtt aaggtcaaag acagaggtga ggggatctca gaagaggata
    24601 ttaagcatat ttttgagcgc ttctaccgca ccgataggtc cagaaatcga accagcaccc
    24661 aagcaggtct tgggattggc ttatccattt taaagcaaat tgttgatggc tatcatttac
    24721 atatggaggt tgagagtgag ctaaataaag ggtcggtctt tattttgcgg attcccttag
    24781 ctgatcatca aggctcatag ctgtatacct gcctgagtat ctagtagatg ctcaggcttt
    24841 tgactgttct aatgtgtggt gtgatgatga ggtgtttatc agggaaggag ggctcttgga
    24901 ggtaaacctg agtgcttgtc tattcttttg ttatccctaa aattatggta aaatagggta
    24961 ttagattaac gatagaattg gggtgtttgc gtgcgttgtc cgaaatgtaa ctataataag
    25021 tcaagtgttg ttgatagtag acaggcagaa gatggcaata cgattcgtcg ccgcagagaa
    25081 tgcgaaagct gtcacacgcg ctttacaacc tttgagcgct tagaagagct tccattacta
    25141 gtgatcaaaa aggacgggac tagggagcag ttttcaagag ataaaatctt aaatggtgtt
    25201 gttcaaagtg cccaaaagcg tccggtgtca agtactgaca ttgaaaatct catttctcgc
    25261 attgagcaga aggttcgtac agcctatgaa aatgaggtgt caagtactgt tattggcaat
    25321 ctggtgatgg aggaattagc agagcttgat gagattacct atgttcgttt tgctagtgtc
    25381 tataaaagct ttaaggattt agacgaaatc gaagagctct tacagcagat tactaatcgc
    25441 gttagaggaa aaaagaagag cagtgtagat gatgaagcct attgatacct tttcttatat
    25501 taagcataat caggttcaat acgattcaag cagcctgatt cagttgtatt ttcctattat
    25561 tggaaatgac gcagtggcag tttatcagta tttggttcac ttttttgatg atggctcagg
    25621 agcccacaaa tttagtgata ttttaaacca tctgcagttt ggaatgaagc gcctagagga
    25681 agccttggtg atgctgacag ctattgattt gctggtctta tatcagctgc cagatgctta
    25741 tttgataaaa ctacatcagc ccttgggcag ggaagccttt ttaaataacc caatttatcg
    25801 taggctttta gagcaaaaga ttggagatgt agcggttttg gagttgcaaa tggtgattcc
    25861 gaaccaggct agaaacatct caaagacctt ttcagatgtt tttggaatag actctcagga
    25921 gcttaagcag cctcagccat caaagataaa ttttgattta gatagctttc agcagctaat
    25981 gcggcgtgac ggtcttaggt ttgaggatca tcaaaaggac gttatcagtc tttacagtat
    26041 ttctgagcaa taccacctaa cctggtttga cacctatcag ctggctaagg caacagcagt
    26101 cggcggcagc attcgcccag agcgcatgct agtcaagaag cagcaagagg gcgctcaaaa
    26161 aacaagtgaa tcgttctcac cagctgagca ggttgttctt agagagtcta agcaggacac
    26221 gcctcttgtc tttttagaga agatcaaaaa agctaggcga gctagagtca caaaggacga
    26281 aaaggaattg ttgctgactc tagcccgcat gaatttcttg gacgaggtca tcaatattat
    26341 ggtattatat accttcaata agaccaagtc agctaatctt cacaagactt atctgatgaa
    26401 aatggcaaat gattttgctt accagcgggt tttaacagcg gaaactgcta ttatcaagac
    26461 acgcgccttt ggtgagcgta agcagcaggc aaagtcacag cagtccaatg tgcctaagtg
    26521 gagcaatccg gattatcaag aaaaaacaag tcaggaagaa caggcaaagc tagagcagtt
    26581 taagcaggct gccttaaaaa ggctggagaa cctaggaaag agtggtgact agatggaaaa
    26641 gatcgggaaa atggtagagc atttgggaca ggctagtcgt gtagctagtg ctgagctgat
    26701 tgaggctata cttgctgatc aggaggtggc tgagtttatc aaggctcacc agctatctca
    26761 ggcagaaata aagctgagtt tatcaaagtt caaccagttt ttagttgagc gccggaaata
    26821 ccagacaggt gatgagacct atattgctaa gggctatcag cccattttgg tcatgaacga
    26881 gggctatgca gatgtgtctt acctagagac aagagagctt gttgaagccc aaaggcaggc
    26941 agctattgca gatcggattc atttggttag tctgccaaga tcttatcgta gggtttcttt
    27001 gtcagctgtt gatgttaaca atgccagtcg tatgcaggtg ttttcagagc ttttggattt
    27061 tgttgagcag tatccagcgg cagagcaaaa gggtctctac ctttatggcg atatgggggt
    27121 cgggaaatcc tatctgatgg ctgctatggc acatgaattg tctgaaaaaa agggtgtatc
    27181 aacaactctt cttcattttc ctagctttac gattgatgtt aaaaatgcca tttcaaatgg
    27241 ctctgtcaaa gaagagattg atgccatcaa gcatgtccct gttttaattt tagatgatat
    27301 tggtgcagag caggcgacct catgggtgcg tgatgaggtg ctacaggtta ttttgcagca
    27361 tcgtatgcta gaggatttgc caaccttttt cacctctaat tacagctttg cagatttgga
    27421 gagaaaatgg gcaaagatca aaggaaatga tgagacctgg caggccaagc gtgttatgga
    27481 gcgtgtgcgt tatttagcac gtgaatgcca tttagaaggg gttaatcgcc gccagggcta
    27541 gctaaacgct agctcaagcg atggataatg agataaagaa aaggagaatc atggttttac
    27601 ctacagttgc cattgttgga cgtcctaatg ttggaaagtc cacgttattt aaccgaattg
    27661 caggagagcg tatttctata gttgaagacg tcgaaggggt tactcgcgac cgcatttaca
    27721 cgactggtga gtggcttaac cgccaatttt cattgattga cacaggtggt attgatgacg
    27781 ttgatgctcc ctttatggag caaatcaagc atcaggctca tattgcgatg gacgaggcag
    27841 atgttattgt ctttgtggtt tctggtaaag agggcgttac tgatgcagac gaatatgtct
    27901 ctaagctctt gtatcgtacc aacaagccag tgattttggt tgtcaacaag gtggacaatc
    27961 cagagatgcg aaacgatatt tatgattttt attctcttgg cttaggagat tccttcccgg
    28021 tatcatcagt tcatggtatt ggtacgggtg atgttttaga tgctatcatt gataacctgc
    28081 cgatagaaga gccagtagaa aacgacgatg tgattcgctt tagcctaatt ggacgtccaa
    28141 atgttggaaa atcaagcctc attaatgcga tcctaggaga agagcgtgtc attgccagtc
    28201 ctgttgctgg tacgactcgt gatgcgattg atacaagctt taccgatgaa tccggtcaag
    28261 cctataccat gattgatacc gcaggaatgc gtaagtccgg caaggtctat gaaaatactg
    28321 aaaaatactc agtgatgcgt gccatgcgtg ccattgaccg atcagatatt gtgttaatgg
    28381 ttattaatgc cgaggagggc attcgtgact atgataagcg gattgcaggc tttgcgcatg
    28441 aggcaggtaa gggcatgatt atcgttgtta ataagtggga caccatcgaa aaggataatc
    28501 atacagtagc taggtgggag gctgatattc gtgatcaatt tcaatttttg acctacgccc
    28561 ctattatctt tgtttctgcc gttacaaagc agcgcttaaa caggcttcct gagttgatta
    28621 agcgtatcag tgatagtcaa agccagcgga tctcgtcagc tattttaaac gatgtgatta
    28681 tggatgctat tgcgatcaac ccaaccccaa cggataaggg acggcgtcta aagattttct
    28741 atgctacaca ggtttctgtg aagccgccaa cctttgttgt ttttgtgaat gaagaagagc
    28801 tgatgcactt ctcttatctg cgctttctag aaaaccagat tcgtgctgct ttcacctttg
    28861 aagggacacc aatcaagctg attgcgcgca atcgcaaata agccctttta ttactcttgt
    28921 tagtattgga agcagcgagt gctgttgatg tgcggtgtct agaccttgtg tgtcaggact
    28981 tttgaccgac caataagcct taccagaaat gagaggctgc tatccaaata gagcttacca
    29041 gcaagcaagg cgtgccaagc attgatgtca catgataatc attagcccta ggctagtgat
    29101 tttttagtgc tttaaagcct atcagaacag ctatatacag ctactcaaat atgttttaat
    29161 agcctttaag agagattttt gcaggaaatc taagctgaag tttgttataa tcaaaggata
    29221 agcaaaaagg tgggagcaga tatggctaga ttaattccgg ggcggattcg caatcaaggc
    29281 atcgagcttt atgagcaagg cttggtgaaa atcatagatg acaggactga ccttcttcga
    29341 gcagaggtgg atacttatca ggttcaatat ggtatcaatg atgaggatat taggtgtcag
    29401 tgtgattatt ttgagcgaaa gcagtattgc cagcacattg cggctctaga atattttctg
    29461 aaaaataatc agaagggcaa gtcgctctca gagcagctta acaaccagct ggaaagtaag
    29521 gaggaaacta aaaagctgac ctcctttggt agtctttttt tggacagttt gcacatgaac
    29581 gaggacgaca cgaccaaata taggctttta gcttctggtg ctaaaagtcc tttctcatct
    29641 gattactggt ggagccttaa gataaatcgc ttgcccggag agaaggctta tgttatccgc
    29701 gatatcaagg cctttattca tttggtcaaa gttgagggct tttaccagat tggaaagaat
    29761 tactttgagt ctctttccat attgcagttt gatcaggcta gtcaggagct gattcgtttt
    29821 ctttggcgtt tatcaacgca ttcagataag ttagattacg aatggctatt tcctaaccac
    29881 gctcgtcatc ttcggttacc ggcaggcttt tttgaggagg gcattgacct gctgacgggg
    29941 ctttacgagt tttcatttga gacctcctct caaacctatt ctcatcttta tgttcgacct
    30001 ctggaggcag aggctggtct ctttcagttt acagttgatg ttcatcgcag ctctattgag
    30061 ctttacatta aggaaaaaaa tatagagtat tttttcaata atgaatacct gctatacatg
    30121 aacacctttt accacctgag cctgaagcag caaaaaatgg ttcaagctat tcgcagcctg
    30181 cctattgagg ccgatttggc caagcacatt cattttgatc ttgatgatca ggctaagctg
    30241 gcagctagct tgctggaatt tcgagagctt ggtcaggtga aggctcctaa aagctttgat
    30301 attagagatt tccaagtgac ttttgtcttt gatattactg aaaaaggtga gttgacctct
    30361 cagctgattt ttgactatgg gagcattcag atcagtgata aggcaagctt agaccagctc
    30421 ccctttgcta gccattataa aaaagaaagc agtatttatc gtgccttgaa gcgctttggg
    30481 ctttctccgc agttttttgc taagaaagcc ttgactgacc ccaaggactg gtatcgcttt
    30541 tttacagaag ctgttcctta ttttgaaagt ctaggtaggg ttcagctttc ctctaagctc
    30601 caagatcagc gcttaatgga aagccctcag cttacagtca aacgtgaggg aggtctttta
    30661 gatatttcct ttgatttttc aacggtttgt cagactgata ttgaaaaggc tttggccact
    30721 ttgtttagtg atcgctctta ttttgtcaat cagtcaggca agctggtcgt ttttgatgaa
    30781 gagacacaaa aaatcagccg tagcttacag gaactaagag ctaagcagct ggcaaatggt
    30841 cacctccagc tagaaggaat agctgccacc cagctgtctc atctattttc ggatctgtct
    30901 tctgttcatt tttctgagga gctagagacc ctaatcaagg acctgcagca cccggatcgc
    30961 tttgagctgg gagagctggc cgttaaggcc aaggtgagag attatcagct gcagggcatc
    31021 aaatggctct ctgtgcttga taagtatggc tttggtggta tcttggcaga tgatatgggc
    31081 ttgggcaaga cactgcaaat cattgccttt ttatcaagca ggctaaccga gacctccaag
    31141 gtgcttatct tggcaccctc tagcttgatt tacaattggt tagatgagtt tagtaaattt
    31201 gcccctcaga tagatgctgc tgtatcctac gggctaaagc cggcacgaga tgctcttatt
    31261 caagaaggac atcaggtgac gattaccagc tattcttcct ttaggcaaga tttagaaacc
    31321 tatcaggcaa atgattatga ttatttaatc ttagatgagg cgcagatgat taaaaatgcc
    31381 cagaccaaga ttgctcagag cctgcgtgcc tttgacgtga agaattgctt tgctttatct
    31441 ggtacgccga ttgaaaataa gctgcttgaa atctggtcca tttttcaaat tgttctgcca
    31501 ggcctgctgc catctaaaaa agcctttttg aaaatggagg ccagagacgt ttctcgctat
    31561 attaagccct ttgtcatgcg acgcaaaaaa gaggaggtct tgccagagct accagaatta
    31621 atcgagatga attattacaa tgagatgtcc gatggtcaaa aagcgattta tctggcacag
    31681 ctaaggcaga tgcaggagcg gctgtctgct gcaactgatg atgatattaa tcgcagtaag
    31741 ctggaaatcc tgtctggtat cacacgtcta aggcaaatct gtgatactcc tagcctgttt
    31801 atggattatc aaggaggaag cggtaagcta gacaatctaa gaaccttgct gctgcaaatt
    31861 aaagaaaacg gtcatagggc tttgctgttt tcacaattta agggcatgct ggctcttgtc
    31921 aagcaggaaa tggatcagct tggcttatca tcttatacca taacaggctc aacaccggcc
    31981 aatgaccgtc aagaaatgac acgtgccttc aataatggct caaaggacgc ctttttgatt
    32041 tccttaaagg ccggtggtgt tggactcaat ttaacaggtg ctgatactgt tattttgatt
    32101 gatctatggt ggaacccagc tgtagaaatg caggccatta gtcgtgctca tcgtattggt
    32161 caggaggaca atgtagaggt ttaccggttg attacccgcg gaacaattga ggaaaaaata
    32221 ctggagcttc aggaaaataa gcgtcatctg attaccactg ttttagatgg caaacaaggc
    32281 ctagcaagca tgtctgtcga ggagatcaaa gaaatccttg gtcttcagcc ctagcatgta
    32341 tggcttttag cacacgctct taagcctatc agctaaaggc tagtgtctgt tctctataac
    32401 aaataaggca agagaataga ggtgatgagc tagtcacatc atttttgctt tgctgccttt
    32461 ctttttagga attactttga aaaataggat tatttagttt ataataggga atgctatagg
    32521 aaggagagtg agatagaatg acaaagcatg cgtttcctct ggttgcagat ggtgagccta
    32581 ttattgagtc agctaggcag atggctttat atgaaaacga agatttgatc acaaatattg
    32641 ctggcagcta tcaagataaa cattacgacg acatcataag agaccatcaa tttgctgaga
    32701 agactcctgt cgtctctaaa ggatcccttc atcattctcc agttgtcgat gaagatcata
    32761 gctacgctca aaaggccaga aggcaagcaa agcaggatgt caaagaaaaa agacaggctt
    32821 atattgctaa aaatatggct tatagcccaa agcaggcaag caagaaaggt caaagtgggg
    32881 ccttctcttc taaaaaacca gcgacagaat tgagccgttt tacagagaaa ttaaaccaag
    32941 agtcttatat tttagctgag cttcctcgtc aatataagga gccgcaaaat accagccaag
    33001 cagctgtcaa aaaaaataat tatgactttt tgaagcgcag ccaaatctac aatcatcaag
    33061 aagacagaga tcatcgtgaa aagaccattg ctcaagagct aaacctgagt cgctttgaag
    33121 atattaagta agctttatac agccttatgt ctgtcaacat taaaaggagt taacatgtca
    33181 aaaacctatc attttatcgg aattaaagga tctggaatga gtgccttagc cctgctgctc
    33241 catcaaatgg ggcataaggt tcaaggcagt gatgtggaga agtattattt cacacaaaga
    33301 ggcctagagc aagcaggcat taccattttg ccctttagcg aagataatat ttctccggat
    33361 atggagctga tagcaggtaa tgcttttcgt gaggacaaca atagcgaggt tgcttatgcg
    33421 atgcgtcatc agctgccctt taaacgctac catgagtttt taggtgagtt tatgaagcag
    33481 tttactagtc ttggtgtagc cggtgctcat gggaaaacct ctaccacagg cttgttgtca
    33541 catgtgctca agcacatgac ggctacttct tatttgattg gtgatggtac tgggcatggg
    33601 gctgccgatg ctcgttattt tgtgtttgaa tcagatgagt acgagcgtca ctttatgcct
    33661 tatcacccgg aatattctat tatcactaat attgattttg atcaccctga ttattttaca
    33721 ggccttgatg atgtgttcaa tgcctttaat gactatgcta agcaggtgaa aaaggctctt
    33781 tttgtttacg gtgaagatga ggaattaaga aagattagct ctcctgcacc gatttactat
    33841 tatggctttg aggacactga tgatttcgta gcctttgata tcacacgcac gacaaatggc
    33901 tcagacttta aggtaaagca caagggtcat gctattggtc agtttcatgt tccagcctat
    33961 gggcgtcaca atattttaaa tgctactgcg gtgattgcta atttatttat tgcaggcttt
    34021 gatatgaagc ttgttgcaga gcatctgaag agcttttcag gggtgaagcg tcgttttact
    34081 gaaaaggtga tcaatgacac tattattatt gatgactttg ctcatcaccc aacagaaatc
    34141 attgcaacgc ttgatgctgc taggcaaaaa taccctaata aggaaatcat cgctattttt
    34201 cagccacaca cctttacaag gaccattgct ttgctagatg actttgccca tgccctaaat
    34261 gaggctgaca gtgtttatct agcgcctatc tacggctcag cgcgtgaggt tgataagggt
    34321 gatgtcaagg tggaggatct agcggctagg gttgagcgcc cagccaaggt catctcagtt
    34381 gacaatgtat caccgctgct ggatcatgat aatgcagtct atgtttttat gggagcaggt
    34441 gatattcagt tgtatgaacg ctcgtttgaa gagctgctgg ctaacttaac taaaaataat
    34501 caatgattaa gcgacctgcc ttaggcaggt tttctcgtcg taaaggagga cctatgctaa
    34561 ttagacatgt gaatcagact gactgggaga ttattgctga tatcgaacag gccaattttt
    34621 ctccccaaga ggctgtagca gccaatgtga taaaagagcg tgcagagctt atttcggata
    34681 cctttcttgt ggctgttatc gccaatcagt ttgtcggcta tatcgaagga cctgtcattg
    34741 ctgagccaag gcttgaggat cacctatttc atggtgtgac caagaatcca gcaagaggtg
    34801 gctatatagc cattaccagt ctttctgttg ctcctggata ccaaaagcag gggattggca
    34861 cagctctctt agctgcaatg aaggatttag cagttgcaca ggatcggctg ggtatcatac
    34921 ttacctgtca tgactatttg attccttact atgagatgaa tggttttcaa gatcaaggcc
    34981 tgtcagcttc aaagcatggt ggctctgttt ggtatcaaat gctatggcag ccataggaag
    35041 gctattaaag cttagcatgt attaagaatt agtaacaaaa gggggatttt attgcattta
    35101 tagtgcaatt aggatataat ggcggttgat taagtttagg aggaatggct ttgactgatt
    35161 ttaaagatga tgagcaaaga cgtcagcagc aaaaaagctt caaagaaaag attctagccg
    35221 aattagaaaa agcaaatcag attagaaaag aaaaagaaga agagcttttt aaaaaggatc
    35281 tagaggttca agaggctgct agaagaacag ctcagcttta tgcagaatat aaaagacaag
    35341 aagcactaag caataacccc aaacaagcgt ctgatatagc agctgcgtcg caagagacga
    35401 cctcaacggc ttcaacagcc cacacctctg cgattaagct agaagagaca gcagtagcta
    35461 ctggggatca agcattgtcg ccaccagagg agcctgcatt gagtgaaagc ctgcttaagg
    35521 aagaggcaag tgtcgaaggt cagactaaga agggtggtcc agtgagaaga aaaacaagta
    35581 agcgccagca gacagatcga atggccaaaa aaatttcgac agtactgata tcgtcgattg
    35641 tcgctattat tgtggtgatt ggcctcgcag ggacagccta tgtgtatagt gcccttaacc
    35701 ctgttgacaa aaatagcgat gactttgttc aggttgaaat cccagccggc tcaggcaata
    35761 agcttattgg gcagatcctt gaaaaagagg ggctgatcaa aaatagtacc gtctttagct
    35821 tttacactaa gtttaaaaat ttcactaatt ttcaaagtgg ctactacaac ctacaaaaga
    35881 gcatgagcct agaagacatt gcccaggcct tacaagaggg tggcacagca gagcctacaa
    35941 agccagtact aggaaaaatt ttaattccag agggctatac cattaagcaa attgctaagg
    36001 ccatagaaac taatagtagg gcaaagaatc gtagcaaggc taaaacacca tttcactcaa
    36061 aggatttctt gaatttggtg acaagtgatg cctttattca agagatggct aaaaaatatc
    36121 cgaaattgct aggagatctt ccaagcaagg aagtagctac ttatcagcta gaaggctacc
    36181 ttttccctgc gacctataat tattataagg aaacaacact aaaagacctt gcagaggaaa
    36241 tgattgcagc ggcaaatgca aacctagcgc cttattatga ggcgattgca gctagtggca
    36301 agacagttaa tgaggtgctg actttggcct ccttagttga aaaggaaggc tctactgatg
    36361 acgatcggcg tcaaattgcc agcgtatttt acaatcgctt aaataatggc atggccttac
    36421 agtctaacat tgctatattg tatgcaatgg gtaaattggg agaaaagaca accttagcag
    36481 aggacgctgc tattgacaca accattaatt ctccttataa tgtttatatc aatactggct
    36541 taatgcctgg tccagttgat agtccagggc ttgcagctat tgaggcgact atcaatccag
    36601 cggcaacaga ttacgtttat tttgtagccg atgtgcgtac tggtgaggtt tattatgcaa
    36661 aaacatttga agagcactct gcaaatgttg aaaaatatgt taacagtcaa attcagtaag
    36721 gacaaacatg gtgctttagc atcatgtttg tgtttctgat tcgtcaaaag aaaaaggaaa
    36781 agagaaagat aatggcagaa aagacttatc caatgacagc agcagaaaaa gaacagcttg
    36841 aaaaggaatt agaagagcta aaattagttc gtcgtccaga ggttgttgag cgcataaaaa
    36901 tcgctcgttc gtatggagac ctttctgaaa actctgaata cgatgctgct aaagatgagc
    36961 aggcttttgt tgagggacaa atctcaacct tggagacaaa gattcgctat gctgagatta
    37021 ttgatagcga tgctgttgcc aaggacgagg tggcgattgg taagacagtt gttgtccagg
    37081 aggttggcac acaaacaaca gacacttatc atattgtcgg tgcggcagga gcagatattt
    37141 tttctggaaa gatttcaaac gagagtccaa ttgcacaggc cttgattggt aagaaaacag
    37201 gagataaggt taagattgag tctccagcag ctacctatga ggttactatc atcagcgttg
    37261 acaaaacaca ataagactta tctgactatc agtgcagtgt cctgatagtc tttttagtgg
    37321 cttgcttttt aatatcagtt gttgtggtct attaaaaaga gctgcacttt agaaagtttt
    37381 aactaagata ctttatgacc tagtctcata cattaaaaaa gcgaacaggt ctaattttcg
    37441 gaatccctga aaattagacc tgttcgtttg ttttatcttg agtcagactt ttgtcacaga
    37501 ctcttttagc tatcttagcg acgctttttt tgtttaccgg cgtttcggtt taacttagtc
    37561 ctcttgcttg tgctaagggc ttgcttttca gctgtaacgt ccttgcgtgg ctggtgagat
    37621 ttataggcct taggagggtt ctttgcgaac tcctctgcaa tttgcttgcg gagccttggt
    37681 tttaaaaggt aggttgtgat caattgctga atgatactaa agaaaccacc aactagccaa
    37741 tacaagccta atccggcagg caggtaaaac gacatgacaa tcatcataat tggcatggtg
    37801 tacagcatgg ctttcatttg ttcacgttgc tcctcaggga ctgccatcat tgacagccag
    37861 gattgaacga agtataaagc cgcaattaca gctgtaagca agacgctgcg atgccccagg
    37921 tcaatgccca taaaggtact tgttgagact cccttggtaa attggaccgc aacatacatg
    37981 gcagaaaaga aaggcatttg aatcagcagt ggcaaacagc ctataccgcc tagcgggttg
    38041 actccatttt cacgctgggc cgccattaat tctgtttggg ctgccatttt ttcttcagtg
    38101 cttgtagcgt ttttgatgcg ttgattaatt ggctcaaaaa aaggctttag gtaggccatt
    38161 ttttctgatt ggtagcttgc cttccatgat tggtagagcc caagtggtag gataatcgtt
    38221 ctaacaataa tagttacaac aatgatggca agaccatagc ctagggcggt gctgttagca
    38281 aagtaatcaa tgagaaagga aacgggcttt ccaaggtaat cccaaatgat gccctccggg
    38341 tgccccttgg cgtctctgcc gacacaccct gtcaatgtca gtaggaccga taaggcaagt
    38401 cctgagaaaa gtatgcgatt cgttttgagt ttcaatgtgt ttgtccttta atttttaata
    38461 tacctaacca ttttactgtt tttttgagaa attaacaata gttctacagt aggattttta
    38521 attgctgatc ctaaaatcat ggaaatcctc aaagtgagat ggattaacat caacataggt
    38581 cacctttgcc catttagaag gtccttttct gatttcctgg ataaagcgcg tcatctttgc
    38641 agggtcacta gcctgtgcta aaatctcaac agtcccatca ctattgttcc acacgcggcc
    38701 gtaaatatca ccaatttcca aagctagtgc gtaggttgaa tagcgaaagc caacaccctg
    38761 caccctgcct gaaacgatta gtctgacctt tttcataagt cacctctttt ctttttatta
    38821 tagcatagat agcttataaa tactaaaagt tgtcatggag caggcagcca aaggataggc
    38881 aaagactgca agtgggctat ctgctgaggt aaacaatagg tcttagtgca gcaaggctat
    38941 gtttatggtt agctctcctt cttgtcttct aaaaaggaaa gctaatgggc ttacgacacc
    39001 tgataagggg agaaagctcc ttttaggctg atagccttct gatggttttt atgcaaaaga
    39061 gtgaacaatt ttgtg
//
LOCUS       DARYUW010000014        39068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYUW010000014 DARYUW010000000
VERSION     DARYUW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(93..464)
                     /locus_tag="TVW11_000621"
     CDS             complement(93..464)
                     /locus_tag="TVW11_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364748.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TVW11_000622"
     CDS             683..1321
                     /locus_tag="TVW11_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1364749.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TVW11_000623"
     CDS             1517..2053
                     /locus_tag="TVW11_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1364750.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TVW11_000624"
     CDS             2916..3320
                     /locus_tag="TVW11_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1364751.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TVW11_000625"
     CDS             complement(3376..4860)
                     /locus_tag="TVW11_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1364752.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TVW11_000626"
     CDS             5219..6442
                     /locus_tag="TVW11_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1364753.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TVW11_000627"
     CDS             complement(6532..6891)
                     /locus_tag="TVW11_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1364754.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7775
                     /locus_tag="TVW11_000628"
     CDS             7056..7775
                     /locus_tag="TVW11_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1364755.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEAGWVSC"
     gene            complement(7820..8647)
                     /locus_tag="TVW11_000629"
     CDS             complement(7820..8647)
                     /locus_tag="TVW11_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1364756.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8908..9036
                     /locus_tag="TVW11_000630"
     CDS             8908..9036
                     /locus_tag="TVW11_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1364757.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9090..10403
                     /gene="obgE"
                     /locus_tag="TVW11_000631"
     CDS             9090..10403
                     /gene="obgE"
                     /locus_tag="TVW11_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1364758.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10524..10682
                     /locus_tag="TVW11_000632"
     CDS             10524..10682
                     /locus_tag="TVW11_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364759.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10735..11439)
                     /locus_tag="TVW11_000633"
     CDS             complement(10735..11439)
                     /locus_tag="TVW11_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1364760.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11774..13174
                     /locus_tag="TVW11_000634"
     CDS             11774..13174
                     /locus_tag="TVW11_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1364761.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13184..14278
                     /locus_tag="TVW11_000635"
     CDS             13184..14278
                     /locus_tag="TVW11_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1364762.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14384..16378
                     /locus_tag="TVW11_000636"
     CDS             14384..16378
                     /locus_tag="TVW11_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1364763.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16392..16709
                     /locus_tag="TVW11_000637"
     CDS             16392..16709
                     /locus_tag="TVW11_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1364764.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16706..17041
                     /locus_tag="TVW11_000638"
     CDS             16706..17041
                     /locus_tag="TVW11_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1364765.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17041..17475
                     /locus_tag="TVW11_000639"
     CDS             17041..17475
                     /locus_tag="TVW11_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1364766.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17550..18929
                     /locus_tag="TVW11_000640"
     CDS             17550..18929
                     /locus_tag="TVW11_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1364767.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18926..19078
                     /locus_tag="TVW11_000641"
     CDS             18926..19078
                     /locus_tag="TVW11_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364768.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19235..19975)
                     /locus_tag="TVW11_000642"
     CDS             complement(19235..19975)
                     /locus_tag="TVW11_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1364769.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(19975..22140)
                     /locus_tag="TVW11_000643"
     CDS             complement(19975..22140)
                     /locus_tag="TVW11_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1364770.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22332..24323
                     /gene="uvrB"
                     /locus_tag="TVW11_000644"
     CDS             22332..24323
                     /gene="uvrB"
                     /locus_tag="TVW11_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1364771.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24662..24805
                     /locus_tag="TVW11_000645"
     CDS             24662..24805
                     /locus_tag="TVW11_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1364772.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24817..26355
                     /gene="dltA"
                     /locus_tag="TVW11_000646"
     CDS             24817..26355
                     /gene="dltA"
                     /locus_tag="TVW11_000646"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1364773.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26352..27599
                     /gene="dltB"
                     /locus_tag="TVW11_000647"
     CDS             26352..27599
                     /gene="dltB"
                     /locus_tag="TVW11_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1364774.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27617..27856
                     /gene="dltC"
                     /locus_tag="TVW11_000648"
     CDS             27617..27856
                     /gene="dltC"
                     /locus_tag="TVW11_000648"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1364775.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27849..29102
                     /gene="dltD"
                     /locus_tag="TVW11_000649"
     CDS             27849..29102
                     /gene="dltD"
                     /locus_tag="TVW11_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1364776.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29136..30110
                     /locus_tag="TVW11_000650"
     CDS             29136..30110
                     /locus_tag="TVW11_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1364777.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30651..31910
                     /locus_tag="TVW11_000651"
     CDS             30651..31910
                     /locus_tag="TVW11_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1364778.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     GKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32083..33783
                     /locus_tag="TVW11_000652"
     CDS             32083..33783
                     /locus_tag="TVW11_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1364779.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33812..35944
                     /locus_tag="TVW11_000653"
     CDS             33812..35944
                     /locus_tag="TVW11_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1364780.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSTAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36020..37324
                     /locus_tag="TVW11_000654"
     CDS             36020..37324
                     /locus_tag="TVW11_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1364781.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37325..38185
                     /locus_tag="TVW11_000655"
     CDS             37325..38185
                     /locus_tag="TVW11_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1364782.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38210..39040
                     /locus_tag="TVW11_000656"
     CDS             38210..39040
                     /locus_tag="TVW11_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1364783.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10865 a         7374 c         9045 g        11784 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggctggc tgggttagct gctgaattga tagtaaaaaa gaccagtctt
     7801 agactgatct gtagggtgat tagatcgccc attctcctcc tcggaagatt ggaatgactt
     7861 ctccgtcttt ggtaatgcca tcgatatcca tttgttcaga accaatcata aagtccgcgt
     7921 gggctgttga gcgatttagg ccagccgctt cccaaatgtg ctgctcaggc attccaagtc
     7981 ttaggtcagt tcctggtgcc ctgtagtgaa ggctgtcaaa ctgataatca ttgaggagcc
     8041 ttgccttttt ttctaaacgt tcctgatgtt ggtcccaggc cttgacagga tctgtctcgt
     8101 aaatgcgatt cattttgaaa atggcatccc acaaagcgtc cacctgctct tcttcgcttg
     8161 tcaggtttgg aaaaaccata gcagcccatt cgggaccggc tgcagctgct agattccagc
     8221 tgactttgtt ggcctgagtg gcagcccgct gtttttcaag agcaatagct gttgcgcgtg
     8281 ttgctccagc tagcctatca gaatcaatat cagcaaagac gtttggattg gcagagcgaa
     8341 tgactaagcg gcttgctttt tgatcaagga gataatgtga ctgttcaacg acataatctg
     8401 gtacctgcaa gagacggtct tcatcagcct taagaagctt ctcgcgtgtg atctgatcgt
     8461 cattatagtc aacaagaacc tcagctgcac cagcctcata ggcttttttg gttaatagcc
     8521 gcgcaagctt gtgttgctct actgcaatag aaatgagtag tgtgtgacct ttttgaatgt
     8581 tgactccttt tttgataaga aggttagcgt atttttcaag ataatcgtca aaatgtggca
     8641 aaaccatagc agtctcctaa tatgttaatg ttgcaaaatt taatgtatca tatttgcgac
     8701 tatttcacaa ggagctagcc tgtttcatag gctaaatgtc tcctagaatg cctatcgtaa
     8761 aaggctcagt gttggttttc tctgatgagt taaaaaacga tccctttttt gatcagtttg
     8821 cgctgccctt gctaatagat atttgcttaa tagcgacatt cgtgttaaga tataagagga
     8881 aaaaatcaat agatgaggta tttaacagtg gcatttggag aaaatggacc tcgcaaaaaa
     8941 actgcctttg aaaagttgac aacagttgtt gtgatcgtga tggttcttgt gactgtcggt
     9001 ggacttattg cgggtgccct gtcagtattg atgtaagaaa acgctgaaag gcgttttttt
     9061 aggataagag aaggtttgag aagaaaagta tgagtatgtt tttagatact gctaaggtca
     9121 gtgttcaggc tggtcgtggc ggtgatggta tggtggcctt tcgtcgtgaa aaatatgtgc
     9181 ctaatggcgg cccttggggc ggtgatggtg gcaagggtgg ctctgtcatt ttcaaggttg
     9241 atgaaggttt gcgtacccta atagactttc gctacaatcg taagttcaag gccaaatccg
     9301 gtgaaaaagg catgactaag ggcatgcatg gtcgtggctc agaggatttg attatctcag
     9361 tgccacaggg aacgactgtg cgtgatgctg aaaccggtaa ggttctgacg gatctggttg
     9421 agcatggtca agaatttgtc gtggctaagg gtggtcgtgg cggtcgtggg aacattcgtt
     9481 ttgcaacgcc gcgcaatcca gcacctgaga ttgctgaaaa tggtgaacca ggagaggagc
     9541 gccaattaga gctagagctt aagattttgg cagatgtggg actggttggt tttccgtcag
     9601 ttggtaaatc aacgctacta agcgtggtct catcagccaa gcccaagatt ggtgcttatc
     9661 actttaccac tattgtgcct aatctaggta tggttcgaac caaatctggt gagagctttg
     9721 ctatggcaga tcttccaggc ttaatcaagg gagctagcca gggtgtgggg cttggcactc
     9781 agtttttgcg ccatattgag cgtacacgtg tgattctaca tgttattgat atgtcagcag
     9841 ctgaaggacg agacccttat gaggactatg tggcgattaa taaggagtta gaagcatata
     9901 atcttcgtct tatggagcgt ccgcaaatta tcgtcgccaa taaaatggat atgccagagg
     9961 caaaggagca gttgcagcgc ttcaaggaac agttagctgc tcagtatgat gactttgaag
    10021 aactgccaat aattttcccg atttctagct tggcacatca aggcttggat agcctattag
    10081 aagcaacagc agagctatta gcaaaaactg atgatttctt gttgtatgat gaggctgatt
    10141 tggctgagga cgaggcttat tatggctttg cggctgagga aaaggccttt gagattagtc
    10201 gtgctgatga tgcagcttgg gtattgtctg gtgagaaatt agagcgtctc tttgtgatga
    10261 ccaatctgga gcgcgacgaa tctatcatga aatttgctcg tcagctacgt ggcatgggtg
    10321 ttgatgaagc gcttcgtgag cgtggtgcta aggacggcga cattgttcgc attggcaagt
    10381 ttgagtttga atttgtagac taatgacaaa taccaagctt agctgttttt tgtagcaagt
    10441 gatgctgagt catatctgaa gtaggctgtt tgctcaattc acagcaatga ggtcttggtt
    10501 gatgtgagct agggaggttt tttatgggag ataaaccaat atccttcaag gataaggacg
    10561 gtaactttgt ttcggcagca gatgtctgga atgctgaaaa attagaagaa ttatttaatc
    10621 tcttaaatcc caataggcgt ttgcgtttgg aacgtgacaa attaaaaaag gatgaagctt
    10681 aagtgcactt cctctcaatc gttagattta gtgtctaact tttgagggtg cacttcaagg
    10741 cttcgtcctt ttttgatgct ttttttcttg gtgatgctgc aaatgtagcc aattaaaaaa
    10801 ggtgtaaatg tcattaacaa gaaaggctgc aaaacaaatg accactgcgt attggctggt
    10861 atttgcttga gcagcataga gccacaggag aattaagacc aaatcattaa gagcataggc
    10921 caaggcaaaa taagggctac gtttgtagct taagtaggct gctgaaaaag aggtggcaat
    10981 agataaggta gaaacaggca gataggctgt cttaagatag gctaagatag catagaacaa
    11041 gctggtaact agtatggtaa gaaccactaa gcgcagccgg tctgctgttg tcaagcgtga
    11101 gatggttacc tgagatgtct ggtcttcaaa tgggtggctt agccaggtaa acagtgacaa
    11161 aatagccatc ggcagggtca tgaagagata ggttatcagc tccccgtaat aactgtttaa
    11221 tagtgacaga taggcataaa taagggagaa aataatggcc aagctctgtc caatcggatt
    11281 tgccttggca ctaaagatta aagctgtcac accgattaag gaagctatca gtgctaaggg
    11341 agcttgttct ccaaagaaaa aggcactgag gagaatagcc gaaatggagg ttaaccaaag
    11401 cgtccactcg gtttttgtaa aatagtttaa ataagccata tccttattca agcataggcc
    11461 tttttatctg tcaatagggt gtcgacctta gggaaaaata agctaatacc tgccatagtg
    11521 caattggttg tgaggcacta atactagcag ataatggtgt taactagagg caaatgagct
    11581 aagagtttcc ttattggctg ctgctaatac tccttgttga ctggtttaga agaaaaggac
    11641 taagagcctt agcttggctt tgtcagttag tttccttgat gataaggaaa aactagattt
    11701 tttaaagcgt ttacagtgtc cttttttctt cctataatag gggtataagt gacaaaaaga
    11761 aaggaaaaag catatgaagc aatcaaaacg ccgttaccaa tttccagaag gttttttgtg
    11821 gggaagctca acatctggcc ctcaaagtga ggggactgtt tctggagatg ggaagggacc
    11881 tagcaattgg gactactggt ttagtctgga gccagataag tttcatcatc agattggtcc
    11941 agaggtaacc tcaacctttt acaccaacta caaaagcgat attgctcttt taaaagagac
    12001 cggtcacaca gcttttcgga cctctattca atggtctcga ctgattccag aaggggttgg
    12061 tcaggttaat ccaaaagctg tagcctttta ccgagaggta tttcaggaaa tcatggctca
    12121 ggacattaag ctgattgtta acctctatca ttttgatctg ccttatgcct tgcaaggaaa
    12181 gagaggctgg gaggctaagg agacggtctg ggcttatgag acctatgcta agacctgttt
    12241 tgagcttttt ggtgatttgg tggatacatg gattaccttt aacgaaccta ttgttccagt
    12301 cgaatgcggt tatttggggc attaccacta tccttgcaag gtagatgcca aggcagctgt
    12361 tcaagtggct taccataccc agttggctag ctcacttgct atcaaggcct gccacgagtt
    12421 gtatcctaag cataggatta gtattgtgct taatgtgact cctgcctatc ctagaagtga
    12481 tcagccagaa gatgtcaagg cagcgagaat cgcagagctt ttccagacta aatccttcct
    12541 agatccgtct gtcttaggag tgtacccaga agagttagta gttcttttag aggcagctga
    12601 tttattgccc cagtatagtg ctgatgaatt ggctattatc aaaaacaatc ctgttgattt
    12661 cttgggagtt aattactatc aacctttgcg tgtgcaagcg cctagcaaaa caagacaaga
    12721 tggtgaacca atcacgctag cctcttattt tgaaccttat gatatgccag gcaaaaaggt
    12781 taaccctcat cgcggttggg aaatctatga gcagggcctt tacgacattg ctcttaattt
    12841 aaaagagcat tatggcaata ttgactggtt agtaactgaa aatggtatgg gagtagaagg
    12901 tgaagaagcc tttttagttg atggtcagat ccaagacgat taccggattg cctttatcga
    12961 agaccatttg attcaattgc acagggcttt agaagaaggc gcgaactgta aaggctacct
    13021 cctgtggacc tttattgatt gctggtcttg gttaaatgcc tataaaaatc gttatggctt
    13081 ggtagccttg gatttagaga ctcaaaaacg aacccttaaa aaatctggcc actggtttaa
    13141 gaccctgagt cagacaaatg gttttgataa ataggagcgt atgatggtca ccttaggatt
    13201 ttccctttac cctgagcggc atggttttgc taagagtaag gcttatattg atttactgca
    13261 ctgctatgga gccaagcgct tgtttatgag cctcttacag ttggcgccaa atgatcccaa
    13321 gacctttaag ttttatgcgg atctgattgc ttatgccaat tgcttgggca ttcgggtcat
    13381 tgcagacgtt agccctgctt ttatcaagca ggctggttgg tcagatcagg ttattgaaga
    13441 ggctcatgct tttggcttag caggcttgcg tttagatgag gccttgcctt tagaggatat
    13501 tgttaggcta acgaaaaact cttttgggct taagattgaa ctcaatatga gtactgacaa
    13561 gagtttattg acagccttgc taaaggcagc tcctgatcgg agtaacctca ttggttgtca
    13621 taatttttac ccgcacgcct ttaccggcct gtcactggag cattttaagg aaatgtccca
    13681 tttttaccac gagcatggga ttgcaacggc tgcttttatc acagcccaat cagcaaagga
    13741 aggcccttgg ccgctgtcag agggcttacc gactgttgag gctcatcggc aattgccaat
    13801 tgacgtgcag gtggaactga tgaaggcgac aggaactatt gatactgtca ttttgtccaa
    13861 tcaattcatc actgaagatg aactcgttca gtgccgtcaa gccttggata gatcagtcat
    13921 gtctattaag gtcaagcctc tggttgattt gacggacata gaggagaaga ttatctgtta
    13981 cccacattgt tatcggggag atgtatcaga ttatgtgatt cgctcaacca tgccgcgtgt
    14041 ggtatatgct caagaagcaa ttgctccaag agagcagccc aagcaggtta agcgaggcag
    14101 tattatcatt gataatgacc gttacaacag gtacaaggga gaattgcaaa ttgcactcaa
    14161 agcctttacc cttagctcaa aggccaatgt ggtcgccaac attaaagagg attacctaag
    14221 cctattagac gagttgaagc cctggcagga gttttcattg gtgattgaga ctgactagtc
    14281 tggcttcaca atcgatacgg aaaatgatgg tcactttttt caggaaacat ttgctaaact
    14341 aagagagtaa agaaagcgtt ttctaaaaga cgaaggagga atgatgctat caaaaaaaga
    14401 aatggctata gtagcatttc taatcagcca aaaagggcag tttgtctcta gtgctacctt
    14461 ggctaaggct attggcatga gtgatcgcac agtcagaaaa tacctaaagg agctgattag
    14521 cagccttcct agtaagggag cgcacatcat ttccaagcaa ggtcagggct actgtttaga
    14581 gattgatcat tctatggcgt ttgagatctt ttggcaggaa agcttggcct ctaaaaagcg
    14641 cttggctgat gtgactcagg tggaagaaac agttgatcgg gagcattatt tgctaaataa
    14701 attcttcttt gaagagcccg tttgggattt tgaagagctc tgccaagaat tgtatattag
    14761 tcggacgacc ctaaaccatg ttttagcggt tattagagac cgtattaggc cttatcagct
    14821 acagcttgat gtgagtcatc agcgcgttca ggtgacaggt aaggaagagg ctattaggca
    14881 ttttatcatg gattattttt ttgctaccag ctttgatgac tccatgtacg ccatagtaga
    14941 caataccttt cttgatcata tcaagtttgc tgatatcaca ataattgttt tagatgaatg
    15001 tcgagatgcc aaactaaagc tttctgattt tgtcatgcac aatttggttt tgcacattgc
    15061 cctaatggtt cagcgtattc ggtctggcta tccgttagca tttttttcca ttccagcagc
    15121 tattcgccaa tcagacgagt atcaagtggc tctacgtatt ttatatcgag tagaagaagt
    15181 gatgggcatt cgttttccta aagaagaagc taactatatt gctttacacc tcaaggttaa
    15241 gcattccgtt gatggcagcc cacaggacaa taaggccgat gacttgctga gaagtcattt
    15301 aaaagcaggt attgtcaagg ctagtcagct gacaggtatg tctttggagg ctgatagcag
    15361 cttgcttcaa ggcctattgg cccatatgaa gcctttagcc acaaggcttg aaaatcatat
    15421 tcagctgacc aatcccttaa ctgaggagat taaaagcaaa tacccagagg cttttgccct
    15481 gactaagcaa gcttttgaga atattcctga gcttcaggct tatgacctgt ctgatgacga
    15541 atgggcttac attagcttgc atatcatggc agctattgag cgctattcca atcgtcacaa
    15601 actgagggtg cttgtggttt gtgccacagg ctatggcagt gccatgatgc tgaaaaatcg
    15661 cttggaaaag gaatttgaag gtcgctttca gattgtagat gttatcagct actatgaaat
    15721 aacacaggaa cgactgcaaa cggttgatgt gattatttct tctatcagcc ttgctaatgt
    15781 catgttttta acgccagtca ttactgtcag tgtcttttta tctgatcaag acatcaaagc
    15841 cattcgccaa tttatcgggg agcaggaggg aataagaaga gaagctgcgt cgtcatcgca
    15901 gatgagcttg gaaaaagcag agcagattct aaaaggtgtc tttagtccta agcgttttct
    15961 ttatgtgaaa gaaaaactat caaagaaggc cttgctgtta aagatgattg cttgtcttga
    16021 cgaagcaatg gatgaagcct ttgttgaggc cttttatcac caaatcgtgt tgagggaaaa
    16081 ttatagctca attgtttttg gtgaggtgct tgcctttcca cacccggcta atcccatgac
    16141 ctattctgaa caggtggtgg tggctgtctg tcaagagcct attgactggg acgagagtca
    16201 tcgggctgtt cactttatct ttttgttgtc accgtccaag ggacgtaaca gctatttaaa
    16261 atatatctca ccgagcttgg tgtcttttgt caatcaagca gagcttcagc aggctttatt
    16321 agaagaacca agctatgcac aattcatcac attatttacc ccactcatca ctgaataaaa
    16381 ggagaagtat tatgaaaacc attatgttag tttgtaatgc cggcatgtca accagtatgc
    16441 tggtgactaa aatgcaaaaa gccgctcaag cgcgtggcat cgaggttgag atttgggcag
    16501 ttcctgtgag cgaagctgac aatgaggttg ctgctaaaac cattgatgtc ctcatgttag
    16561 ggccgcaggt caaattctta ctaaaggact ttaagaccaa atttgaaccg gcaattaagg
    16621 tagatgtcat taacatggct gactatggcc tcatgaatgg tgacaaggtg cttgaaacag
    16681 ccctaacaat gatggaggaa gaggtatgac acaatcatca aacctagagg ccattatggg
    16741 attaatcatg tatggcggtg aggccaaggg caaggctgta gaagctattc atgcagctag
    16801 agatggtcaa tttgaaaagg ctcagcactt gcttcaagag gctacacatt ctttaaatgt
    16861 tgcccataga tcacaaacca atttgctatc tcaggaagca gctggagatc aggttgattt
    16921 gtctttattg ctggtgcatg gtcaggatca tatgatgaca gccttagcct ttattgattt
    16981 ggccaaggaa ttggtcgctg tttatgacaa aatatcaaga atccaaagag gtgagctatg
    17041 atgatgatta cagcagaagg agatgtctct gtcactcaat gcttcaaggc tatactaagc
    17101 tctctccaag aggattatca tgaaaacacc ctgagacggc tgccaccagc tgaattaaaa
    17161 gcagggctaa gctacataaa gcattatggc aaaagcaagg agcataacgt tagagtgctg
    17221 atcacagcct tagaagctcc gcacttatat gctgcttgct ttagctctaa tcatgggcta
    17281 aaaacattaa gctaccgctt agaagctctg ggagagaagc gtaccaaaat aacctattgc
    17341 tacgactatc agccacttga tgtctttcaa aaagccaatc agctgatcat tgggaagctt
    17401 tttaagaaga gcttcaaacg gcaatcacaa gcccaattgg cagcccttat ccaatatgct
    17461 aagcagctaa gctaggggaa gatttgagta cagattatct ggctgattat agggcttatc
    17521 atactaaaaa atagaaacag gagaaaatta tgtcacattt ttcggataag tttatggaga
    17581 tttcaggaaa gatgggatcc cagcggcatt tggttgccat tcgtgattcc tttatttcgc
    17641 taatgcccat cacgatggcg ggctctgttg ccgtcttgct gaatgttttc ttgcgtgata
    17701 ttccaaacaa tatgggctgg actggttttg cagcagccat gcagcccatt attgacatca
    17761 atggttatgt gtattttggg acaattggta tcatggcact cttttttgcc tttgcttttg
    17821 ggtatcattt agctcttatg cacaaggtga atcctttggc tggaggttta atctcctttg
    17881 cttcctttgt cgccaccctt cctcaaagct taaccatttc cacaccactt gaaggggcgt
    17941 cagcaagttt attagcaggc ttaaaggata tgggactatc agtggtcact gcaaatggag
    18001 cccgagtttt agaaacaagc cagtggggag caattgccct caaatatgct ggagcaacag
    18061 gtctttttac agcattgatc attggctttt tatctagctt tgtttatgcg actttgacca
    18121 aacgtaacct gaccatcaaa ttgccagata atgtgccacc tgcggttaat aaggcttttg
    18181 cggctattat tccagggaca gtcgcgattt atgtgtcagc gatcgtagct taccttattt
    18241 ttgccctcac aggctcgtct ctaagtgata tgatttcgac ctatatccaa ttgcctttgt
    18301 tggggctgtc tcaagggctt ggctctgtta tcctgttaac cttcttggtt caattgctct
    18361 ggttctttgg tttgcatggt cacaatgtct tagcacccgt gcttgatggt gtgtacttag
    18421 tggctctaac agaaaataca gctgcctata ataccagtca gagcgttgct aatctgcctt
    18481 atctctggac gagaggctcc tttgatgcct atgcacaaat gggtggttca ggtgttactc
    18541 tggctctgat tattgctatc tttattttct caaaacgtga ggagcacaag accattgcca
    18601 aattatcagc accgatgggc gtgtttaaca tcaatgagcc aattaccttt ggtatgccta
    18661 ttgtcttgaa cccaaccttt gctatcccat ggctaatcgt accaccaatt tgtgctagca
    18721 ttgcttatgc tgccacagca ataggcttga tccctcccgt tttcttgcca gttccttgga
    18781 ttacgccagt tggactttac gcttacttgg ctactggagg tagtgttatg gcaggtctgg
    18841 tttccttgtt taacctcttt gttgcctttc ttatctgggc accatttgtc atgtcagcta
    18901 ataaagaaaa agcgagtgac ctttcatgac agcaaaaaac ggagcaagct ttttaatggc
    18961 tataggattt ttccttattg ccattagtcc aatggttggc aacaaatacc tacatatcgt
    19021 gacaggacta gcttttgttg gcttagggta ttatctcact aagcgcaagc gtccttagtc
    19081 aatgcgagca gctagcccct atgaaaagac aaacctaagg gctagccttg attttctatc
    19141 ttggttatcg catttaaaag caagcaaaaa agcaagggta gatgcttacc tttgcttttt
    19201 ttattttttg acctttaata gaatatcttg ctacttaaac atttaagacc ttatctaaaa
    19261 attcaattaa gcgtgggtgc ttagggtgat caaagatttc ctctggagta ccgtcctcta
    19321 ggaattggcc gccgtctgta aagatcacac gattagccac ttgacgagca aagcccattt
    19381 catgtgtcac aatcagcatg gtcatgccct gctctgctag gtctttcata acgtttaaga
    19441 cgtctccaac catctcaggg tcaagagcag aggtaggctc atcaaagagc atgatatcag
    19501 ggttcatggc aagacttctt gcaattgcaa cacgctgctt ttgaccacct gatagacttc
    19561 ctgggaaagc gtcagcctta tcagctagac cgaccttctc tagaagagca agtccctttt
    19621 ccttagccgc ctcctttgag acctttccaa gctcaactgg tgcaaaggta atgttatcaa
    19681 ggactgtcat atgtggaaag agattgaagt gctgaaacac catgccgata ttttcacgag
    19741 ccttatcaat attggtatta ggatctgaaa gttcaaagcc atcaaccaca accttaccac
    19801 tagtaatgga ttcaaggaga ttgagggtgc gcaggaaggt tgattttcca gagccagatg
    19861 gcccgataat acaaacgaca tcaccctcgt aaaatttagc attaatgcct tttaagacct
    19921 cattttgccc ataggatttg tgtaaatctt gaacatcaat ttttaattct gccattagtt
    19981 aagcctcttt tctaaacgtt ttgcaagcct tgttaagagt gtaatcataa tcaagtagat
    20041 aactgctagg atagcataca tgcggaagga ttgatagttt ctagcgataa tgattttccc
    20101 tgtttggaag agctccacta aaccgatcgc tgagactatg gtcgtatcct tcaaggaaat
    20161 gacaaactga ttgatgaagt ttggcagcat tagcttaatg gcctgaggaa ggataatcct
    20221 tcgcattgtt gtgtgatatg acaagcccaa gctgcgacta gcctccattt gacctgccgg
    20281 cacagcctcg atacccccac gaacaatttc ggcaatatag gctccaccat ttagcgaaag
    20341 tgcaatagta gcagctacaa aatcgttaat cggtgattga tgcccagtca tgctttcaat
    20401 gaggtttggc actccccaga agataaaggc agcaacaatc atcaagggga taccacgcac
    20461 cacatcaaca aagatagtag aagccatgcg caggttcttt gatggggata cagccatcat
    20521 tccaaaaaca ataccaataa ccaaagcaat ggcaaaggag atgagtgtca gaccaagggt
    20581 tgttccaagc ccagccaata attgcttgta gttattagct aaaagtccat aaatagttga
    20641 ctcatcggct gttttgacag atgcctctga atcaaggtat ctgctgatga tggcgtcgta
    20701 ttttcctgat gctttaagag cagccaaacc gttgttaaac atttcgatga gctcagggtt
    20761 ggctcctttt ttaacagcaa aaccatactc accagaaggc tctcccttga taggaatatc
    20821 aagcttgtgg cctcgctgaa tagcgtacct taaaatagct tcatcatcca taagcccgtc
    20881 aatagaacca gaatttaagc tatcgtacat tgaggaggcc tcatcaaagg cttttagacg
    20941 gtaaccataa atatccttgt tgctttcaag gaaatcatag gaggctgttc cttttttggc
    21001 accgactatt ttacccttga ggtccttgta tgatttgata gagcttccgg atttgacccc
    21061 aaggcgaatg tttgatgtgt agtaggaatc tgaaaaatca aaaatctcac gacgtgcagg
    21121 tgtgatagac atacctgcaa taacagcgtc agcctgacca gcttgaacag catttaaagc
    21181 agcgtcaaag ccaggattgc tgatctcaat ggtaaagcct tgctgcttag caattgcctt
    21241 gatgaggtcc atatcaatac cgacatattc tccgctgcca atttgaaatt caaagggagc
    21301 aaaggaggag tcagccacga ttttataaac cggctttaaa ggagtggcct tagcagaggc
    21361 atcgccagta gccttgcctg ctgtgacctt gtcattgctg ccaagccatt ttgtcatgat
    21421 agcttgatag gttccatcag ccttcatagc gcctaaggct tcattgaagt cgtcaatgag
    21481 ataatcatag ccgctgcctt ttttgacagc aaagccaaag cttccaatag cctctccctt
    21541 catgttgatc gcaagatcct gcttttggtt aatggcatat tgaatgacag gctcgtcgtc
    21601 cataacagcg tcaatagagc ctgttgcaag actgttgtac atcaggtcac ctgtgtcaaa
    21661 tgttttaaca gtataaccat acgatttttt gtatttatct aagaaggctt gagcagctgt
    21721 tccattttta acaccgactg tttttccttt tagctcgcta tatttcttaa tagggttagc
    21781 ctttcttgta gcaataacaa tttttgtatc gtaataggga tctgaaaaat ggaagacctt
    21841 ttgacgagca gcagtgatgg tggtgcctgc cataagggcg tcagcttgac cagactgaat
    21901 ggcattgaca gcagcatcaa agccagggaa tgtcatattg atattccaac cctttcgctt
    21961 tgctacttca ttgatgatgt caacatcaat ccccttatac acctgatctg aatccttgaa
    22021 ttcaaacggt gcataagcag tatcagaaac aatatcaatt gtctctgcac ttgcaatccc
    22081 agcagtcatc aaaacaactg acagcattgc aagcatccat gcttttaatg tgtttttcat
    22141 actagtctcc ttaataaaaa taaaaaatat gcctaattat agcagatttt tttcaaacaa
    22201 gcaaatcatc tcttcttttt atgtcataaa acctaacata aacaactaaa atagtcaaaa
    22261 agctttgata gagtctttaa gtccttaact atgttacaat agataagaga taagatattg
    22321 aggaccaata aatgattgat aaacgtgatt ttaaagcatt taagctcgtg tcaaaatatg
    22381 ccccctcagg agatcagccg caggcgattg agaccttggt tgataacatt gaaggtggtg
    22441 aaaaagcgca gattttacta ggagcaacag gaacagggaa aacctatacc atgagtcagg
    22501 tgatcagcaa ggtcaacaag ccaacgttag tggttgctca taacaaaacc ttggccggtc
    22561 aattgtacgg tgagtttaaa gagttctttc ctgaaaatgc tgtcgagtac tttgtatcct
    22621 actatgacta ttatcagcct gaggcctatg ttccttctag tgatacctat attgaaaaag
    22681 acagctctgt taatgatgag attgacaagc tgcgccattc ggccacctca tcgcttttag
    22741 agcgtaatga tgtgattgtt gtggcttcgg tttcttgtat ttacggattg ggctcaccaa
    22801 aggaatatgc tgattcagct gttagcctgc gtcctgggca ggagatatcc agggatcagt
    22861 tgctcaatgc ccttgtagac attcagtttg aacgcaatga cattgatttt caacgtggac
    22921 gctttcgtgt gcgtggtgat gtggttgaag tatttccagc ctcaagagat gagcatgcct
    22981 ttcggattga gtttttcggt gatgagattg atcggattcg tgaaattgaa agcctaacgg
    23041 gtaaagtatt aggtgatgct gatcatttag tgctttttcc ggccactcac tttgtgacca
    23101 atgatgagca catggagcag tctattagca agattcaggc agaattagca gaccagctta
    23161 agctatttga agcagaaggc aaattgctag aggctcagcg cctgcgtcaa aggacagaat
    23221 acgatattga aatgctacgt gaaatgggct acaccaatgg ggttgaaaat tactcacgtc
    23281 acatggacgg gcgttcggca ggagagcctc cttataccct gttagatttc tttccggatg
    23341 attttcttat catgattgac gagagtcaca tgaccatggg acaaattaaa ggcatgtaca
    23401 atggagacaa ggctagaaag caaatgcttg tggattatgg ctttcgtctt ccgtctgcct
    23461 tagacaatcg tccgcttcgt cgggaggagt ttgaaagtca tgtgcaccag attgtctatg
    23521 tctcagcaac gcctggagat tacgagatgg agcagactga tacgattgtg gagcagatta
    23581 tcagaccgac aggtctgctt gatccggagg ttgaagtccg gccaagcatg ggacaaatgg
    23641 acgacttgct tggcgagatt aacctgaggg ttgaacgagg tgagcgcacc tttatcacaa
    23701 ccttaaccaa gaaaatggcg gaggatttga ccgactacct caaggaaatg ggtgtcaagg
    23761 taaaatacat gcatagcgac atcaagacat tagagcgtac agaaattatt cgcgaccttc
    23821 gtttaggcgt ttttgatgtc ttgattggta tcaatctgct gcgtgaaggt attgatgttc
    23881 cggaggttag ccttgttgct attcttgatg cggataagga aggcttccta agaaatgaac
    23941 gaggtttgat tcagacgatt ggtcgagctg ccagaaatgc tgatggtcat gtgattatgt
    24001 atgctgatcg tatgacggat tccatgcagc gcgctataga tgaaactgct cgtcgtcgtg
    24061 ccatacagat ggcatataat gaagagcatg ggattattcc gcaaaccatt aaaaaagata
    24121 ttcgtgattt aatcagtatt tccagagcag ttgaagcaaa agcaacagaa gcagagacaa
    24181 attatgagtc aatgacgcgg tctgaaagac aagaagctat taagcaattg caaaaaaaca
    24241 tgcaggaagc agcagagctg ctggattttg aattagcagc acagcttcgt gacctgatct
    24301 tagagttaaa agcaatggat taagacctga taagctaagt ctggctgtat aagctaggct
    24361 ttttatctgc ttttgagttt gtcctttagg tctgtcttat gatctttggt accagataaa
    24421 tgagtgatat cttgagcttg atctacgcaa gagctagtgc agccactagc ttcagactac
    24481 tttaatgatt taatgaaaga ttgattttga taagacaatt ctgatataat gtaaagtagt
    24541 tggcaaaaat agaaacatta aataaatttt ctttttaata atttaacttt taccttgtca
    24601 acaaggctat tttcggatag aatttcttag tacattattt cactaataca agaaggtaag
    24661 tatgttaaaa aacaagtcaa gactgcgagc tattttcgtt tttgttggga agatagcgtt
    24721 gttttacgtg attttgatgc tgctcgttta tttttttggt tacctagggc atggtcaaag
    24781 taattttatt tataatgaat tttaggagat tgtctgatgg ttaacgatat gattgaaaca
    24841 attgagtatt ttgcacaagc acaaccggat tttccagttt atgattgctt gggagagcgc
    24901 cgtagctatg ggcagctaaa ggaggactca gatagtattg cagcccttat tgagagctta
    24961 aagctaggtg aaaaatcacc tgttttagtt tttggggctc aaagctatga catgctggct
    25021 tcctttgtcg ccttgacaaa gacaggtcat gcttacattc ctgttgatgt tcattcggcg
    25081 ccagagcgtg tcttgtctat tattgagatt gctcagccaa gtcttatcat tgctattgag
    25141 gagctgccgg ttagtattga tgcgattagg gtggttagct tagcagagat agaggcagct
    25201 aaagcagcca aggcagcctt taccatgacc agtcctgtca agggagatga caattattat
    25261 attatcttca cctctggaac gacaggacag ccaaagggag tgcaaatttc gcatgccaat
    25321 cttttaagct ttaccaattg gatgattgag gatgctgagt ttgctattcc tgagagacca
    25381 cagatgctgg ctcagcctcc ttattccttt gatttgtcgg tgatgtattg ggcgccgacc
    25441 ttagctttag gtgggacatt gtttgcttta cccaaggaaa tggtttcaga ttttaagcgc
    25501 ttgtttagca caattgcgga gctgccgata gggatttgga cctcaacacc gtcctttgcc
    25561 gacatggcaa tgcttaatga tgatttttgt caggagaaga tgccaaggct gacccacttt
    25621 tattttgatg gggaggagct gacagtatca actgcaagaa agctatttga acgctttcca
    25681 gacgcacgca ttatcaatgc ctatggtcca acagaggcaa cggtggcgtt atcagcgatt
    25741 tcaatcacta aagatatgat agagacttac acacgcttgc cgataggcta tccaaagccg
    25801 gattcgccta cttatatcat tgatgaagct ggcaatgctc tggagccggg gcaacaggga
    25861 gagattattg taacgggtcc agcagtttct aagggttatc tcaacaatcc tgaaaagaca
    25921 gctgaagcct tctttacctt taatggcatg cctgcttatc atacgggaga tttaggatca
    25981 tttactgagg acaatgtgtt actttatggt ggacgattag actttcaaat caaatatgca
    26041 ggttaccgca tcgaattaga agatgtgtcg cagcagctaa accaatcacc gctggttgaa
    26101 tcagcagtag cagtaccaag gtataacaaa gagcataagg tccaaaatct cttagcttat
    26161 gttgtcttga aggacggggt gagggagcaa tttgcgagag atttggatat taccaaagcc
    26221 attaaagcct ctgttaagga tcatatgatg gcctatatga tgccgtctaa gtttatttat
    26281 cgtgaaaagc tcccattgac accaaatggc aaaatcgata tcaaattctt gattaacgag
    26341 gttaatcatc aatgacgacc ttgtttcatc acatacctta tatggagcct tatggcaatc
    26401 cgatttattt tgtctacctc atcattgctt ttcttccagt tattattggg atctttaagc
    26461 aaaggcgttt ttcgacgtat gaaagctttg tcagcctgat ctttattttg ctcatgtttg
    26521 gtggagagca ctatcagcaa ttgcttgcct ttttagccta tctaatttgg caaaccatca
    26581 gtgttttggc ttacaagcac tatcgtcaaa aggcaaatgc agcgtgggtt ttctatctta
    26641 gcattttagc cagtctattt cctttgattt gtgtgaaggt aagcctcagt ctaacgaggt
    26701 ctttctttag cttcttaggt atttcctatt taactttcaa aagcgttggg atgatcattg
    26761 aaatgcgtga tggggttttg acagatttta gtctaaagga ttttctacgc tttatgattt
    26821 tctttccgac tttttcaagc gggccgattg atcgcttcag aaggtttcaa gaggcttaca
    26881 ccaagcttcc tagtcgtgat gtttaccttg atatgctcaa taaggctgtc atgtatctca
    26941 tgctgggctt tctgtacaag catattatct cttattgctt gggtgggctg ctattgcccc
    27001 ttgctgaaaa taaggctctg actgtaggtg gctactttaa taaagagacg atctatgtca
    27061 tgtaccttta tgggcttaat ctcttttttg attttgctgg ctactcgatg tttgcgattg
    27121 ggttgtctta tttactgggg attaagacac ctgaaaattt caataagccc ttcttatcac
    27181 caaatttaaa agagttttgg aacagatggc atatgagcct atcattttgg tttagggatt
    27241 ttgtttttat gcgattggtc catctattga tcaagcacaa gacctttaag aatcgaaatg
    27301 tgacttcggg ctttgcttac ctgatcaaca tgctggtgat gggactttgg catggcttga
    27361 cgtggtatta tattgcttac ggtctgtttc atggtattgg cttgattgta aacgacgctt
    27421 ggcttcgtaa gaaaaaggaa atcaatcgtc gtcggaaaaa gcaagggctt aagcctttgt
    27481 ttgagggtaa ggtatttcat gctttatcaa tcgtggtcac tttccacgtt gtcttgttct
    27541 cacttctgtt attctcaggc ttcttaaatg agctttggtt tagcagaccg ttacgttaaa
    27601 aaaggagagt ataaaaatgt ctactaaaga aactgtaatt gacttatttg atcgcttgtt
    27661 tatggaagac gtatcagata tgatggacga ggatttgttt gatgctggcg ttcttgatag
    27721 cctaggaacg gttgagctga ttgtagagat cgaatctatc tttaacatta aggtgccaat
    27781 ttcagagttt ggacgtgagg actggaacac tgccaataaa attattcagg gcatagagga
    27841 attgcagcat gcttaaacgg ctttggttaa tcctaggtcc tctaatcatc gcttttggct
    27901 tggtttgtct taccatattc agctttccta ctaagcttag ctattcattg cgccaggaaa
    27961 agtcaaatgc agtggcaatc aatgatagct cctttaaaaa cggcttgatt aaaaggcagg
    28021 ccttgtcaga tcctaactac tgttttgttc cgttttttgg ctctagcgaa tggagtcgca
    28081 tggatagcat gcacccatca gtgcttgcag aacgctacaa gcgctcctac agaccgtttt
    28141 taattgggaa aagaggctct gcttccttat cacaatatta cggcatgcag cagatttcac
    28201 aggaaataac tggaaaaaag gcagtctttg tcgtgtcccc acaatggttt accccccaag
    28261 gcattgatcc tggtgcggtt caattgtatc tatctaatag tcaggtgatt gatttcctct
    28321 taaaagcaaa ggctagtcat aaggaatcac aatttgccgc taaaagaatg ctggacatta
    28381 atccgggagt tgctaaatca gagcttttaa ggaaaattag tcaaggcaag gccttgagta
    28441 gatgggacat tcgtctgctc aaatggcagc aggagctgtc cttaagagag gagtccttgt
    28501 ttagcttcct tggtcgttca acaaactatg aggataggat tttgcctcgt gttaaagggt
    28561 tgcctaaaac cttttcttat gagcgcttga gcgagctagc agccagacgg gctaaggaag
    28621 gaacttcaaa taatcgcttt ggcatcaaaa atgcttttta ttctaagcga attgcaccgc
    28681 aatttcctct ttataagaat tttcagtgcc gtaataatta cactgtgtca cctgagtaca
    28741 atgattttca gctggtattg tcagaatttg caaaacgtaa aacagaggtg cttttcgtta
    28801 ttacacctgt taatcaagcg tgggcaaatt atacaggctt aaaccagagg aggtatcaaa
    28861 aggctgtcag aaaaataaag catcagttaa cctcgcaggg ctttactcgc attgctgatt
    28921 tttccagaaa tggcggagac aagtatttta tggaggatac cattcacctt ggctggaatg
    28981 gctggctagc ctttgacaag gaggttgttc ctttcttaga ggatcaaaca ccaccatctg
    29041 aataccaact ggatccttac ttcctatcaa aggactgggc agatagaaca gcaggatttt
    29101 agggtcaata gaccattaga aaatgaggat tagaattgtt aatgagtatc atcgtcatat
    29161 tgcttatttt agccattgct gttttagtga ttgagtatgg tcaaaagcgg tccttttcta
    29221 gctggctgct tgaaaagatg tttgattatc gtaagtataa gctctctaaa aaggctgatg
    29281 actatgaagg aattgagacg caaagacgtc gtcgcattcc ctaccacttg gataatccag
    29341 aggcggtatt ggggattccc accacagaat atacgattga tggcatgcag gtttttgtga
    29401 tcaatgacca agattctcag gatcagccag tgatttacta tctttatggt agtgtctatt
    29461 tgcgtcgacc tgagacattt cactttaaaa ccattaagca tttgatccat ttaaccaatg
    29521 ccaagctggt gttcccaaat tttgagaagg cgccttatgt cacctataag gagatttacc
    29581 caaagcttgc taaaacttat caggagcttt gtctagccaa tggcgctgcc aaggttagca
    29641 ttattggtga ctcctcaggt ggtggcatgg ccttagcctt ggcgcaatac ctaagagata
    29701 cccaaactgc accacagcca aagcaattaa tcctgttatc tccttggtta gatgttagct
    29761 ttgctaatca ggattataag cattttgaag cagtagaggc ttatttagat gctaggcggc
    29821 ttcgagacat tggtgaattg tgggcaggca gtccagaaga aatgcggtct ccgtatgtca
    29881 gcccattata tggcgattat catgacctgc caaagattgt cacttttgtc gggacaaaag
    29941 agatttttta cccagatatt atgaccctgc atgagcgctt gatggagcaa gggcacttaa
    30001 atcagctcgt tattgctgag cagatgattc atgcttatgc gatcttcccg atacgagagg
    30061 caaggcaggc gcgcaagcag attgccgagc tgattttaaa gaaggagtga ttgttgctat
    30121 aggagtcagt tagccttgct tgtctgatga ggcttgggct tgagatttct agagaagctt
    30181 taaggccttt acttgggctg ttaatgctca ttaaagagga ttataggctt tatactaggg
    30241 cttaggattg ctgttttgct attcaataat attagtttag acttgattga ggaaaggcta
    30301 gttttagtta tggtcctcaa tctttttttg atggtaaaca tgtcaagaca gtttacttgc
    30361 tagggtaata atcctgtgct catttcatga gtggctattt ttatcctaag cttggtggtg
    30421 gaaaaatcag attaaaaaat atgaaatttg ctattgacag ctgtaagcga ttgcattata
    30481 ataaacttaa cttaaacgtt taagttaagt tgaataagct gatttgatca tgcactgcct
    30541 aaatgcaatc aataatctca aagcatttgg tgtagtctag taatcaatga ggcagtttat
    30601 tacggttata caatatttat ttagttcatc cctttaggag gtaaatagct atggcgtggg
    30661 attggaaaaa agcaggtgtt gttggagtag tgtcattggc ttcgatcatg gtattaagtg
    30721 cttgtagcgg aggacatcaa aaagaggcta agcaaaaaga cgacaatacc attgtagttt
    30781 cagttgatga gggctatgca gactacatca aagagattaa gacagccttt gaaaaggaca
    30841 ataaggtcaa ggtcaaggtc aaaaaggaag gtatgattga tacgctagat aagctatcta
    30901 ctgatggacc gacaggtgct tcaccagatg tctttttagc accatatgac cgggttggtg
    30961 ggcttggctc tgaagggcaa attgctgagg tgagcttagg caatgctgac cagtttgatg
    31021 acactgttaa aaagctagtc accataaatg gaaaggttta tggggcacca gatgttattg
    31081 agaccttagt gatgtattat aacaaggatt tggtatcaga ggctccgaaa acctttactg
    31141 acattgaaga gctaaataag gatcctaagt ttgcctttgc ttctgaagac ggtaagtctg
    31201 taggctttct tgctaagtgg acagacttct attatggcta tggcttgatt gcaggctatg
    31261 gggcttatgt atttggagat aagggaactg atccaaagga tttaggtatt ggtaatgctg
    31321 gtgccattga aggcttagac tatgctaaga aatggtatag cgtatggcct caaggcatgc
    31381 aggatactca aaaggctgga gattttatta cagagcaatt cacctctaaa aaggctggtg
    31441 tgattattga tggaccttgg gctgctgcct catttaagga ggctggtgta aactttggag
    31501 tggcacaaat tccaagctta cctaatggcg gtagctatca agcctttggt ggtggtaaag
    31561 catgggtgat ttcaaattat tctaagaata aaaagctggc acagcaattc cttgattatg
    31621 tgacaaatga gaaaaaccaa aaagcctttt atggtaagac acaagagatc cctgccaatc
    31681 tagctgctcg cagctatgct gcagaacaag gaaatgaatt gacaaaggcg gttattgggc
    31741 aattctcaaa tgctcagcca atgccaaata ttccagaaat ggcagaagtt tggggaccag
    31801 gtgcgaacat gttctttgag gtagcagcag gcaagaagac tcctgccaag gctgctaagg
    31861 aagcagctaa aaccattcaa gaggctattg cacaaaaata cactgaataa cataaaaagg
    31921 gaggctggga taaaggtatc ctagtctcca tcttgttacc tatagtatca gagtgggcga
    31981 tgaggagata ataataaaaa gtagtagtga ctagcttgtc ttgtttccca tcttgtccta
    32041 ataagagtat ctgataagac tgatgaacct agggaggaaa aaatgaacac agccggaata
    32101 ctgcatattc cagattctag atattgcttt gccttatcaa caaaggagct tgtgattcgg
    32161 ttgagggttg caaaggagga taacgatata gcggtgacgc tggtttatgg acctaagtat
    32221 cattatcatg agtatcaaaa agaactggcg atgtatgctg cttataccga tcatacccat
    32281 acctattatg aaatcacctt aagtcttgat gatgttagat tggcctatat ttttaagctt
    32341 gagcaatctg gtcacaccta ttactttagt gaggatggct tgaccacaag ctatgatttt
    32401 tcaaatggct tttacaactt ttttcaaatg ccttatatta atgctgtaga cgttcatcag
    32461 actgtccctt gggtgcacaa tgctgttttt tatcagatct ttgttgatcg ctttcatcgt
    32521 ggtgactttg aaaaggacga tagctatatt aatatggctt ggctggatag gccaactcct
    32581 aatagctttg ccggagggga tttgaagggg attacagata agctggaata ccttgaggat
    32641 cttggtatta atgtcattta cttgacaccg attttcaaat ccatcagtaa tcacaaatat
    32701 gatattagtg actactatgc tattgacccg atgtttggga catcgcttga tctccagcaa
    32761 ctaataaacg aggcccacca aagagggatt agaattattt tagatgctgt tttcaatcat
    32821 gctagcagtg attgcgagcc atttcaggac gttttggcac atggtagtgc ttcttcattt
    32881 tttgattggt ttatgattca aggagatcat ccttctgtag agctagctaa ttacgaaacc
    32941 ttcgctgatt gtcactacat gcctaagtgg aatacctcgc atcaggctgt tcaggattat
    33001 ttgattgaga ttggtcttta ttggatcaca gagtatcata ttgatggctg gcgattagat
    33061 gtttctgatg aggtatcgca tgatttttgg agacgctttc gaaaggctgt taaggcagtc
    33121 aaatcagatg cgatacttat tggagagaat tggcatgatg cttatcccta ccttcaagga
    33181 gaccagtatg atggtattat gaattacgcc tttaccaagg cttgtctcga ttattttgca
    33241 tttgatgcga ttagctcaca ggaaatggct gaaagattgt cgcatatttt aatgagaaat
    33301 acttggcagg tcaaccagat gaatctgaat ttactggatt cccatgatac gcatcgcttc
    33361 ttgactcagg tgaatggctc taaggacaaa ttattggctg gcttagccct tttagttacc
    33421 tttatgggca taccatgtat ttactatgga acagagcttg cgatggaggg aggttatgat
    33481 cctgactcta gacgtagctt taattgggac agcagcactt gggatatgag cttttggaat
    33541 caggttaagg acattatcag cctgcgtcgt catgcggtta tccaatttgg aagcatttcg
    33601 ataacctccc atgatgactg cctttgcgta aagcgtgaat taaacggtca atcgataaga
    33661 ttgctggtta ataatggcgt taagccatat cctattgaga aaggaggttc tgtgcttgtt
    33721 tctaatggtg tagataaaga gacatttgag ctactccaga acgggtttgt tgttagctat
    33781 taatatggcg ttttatcaaa ggaggttaag gatgaagcgt attactttaa catgtcgtaa
    33841 agcattaaca gtagctatgg cagcggttac cttagcaatg tcaactaaca gtgtctttgc
    33901 tattgaaaat actgcggtgt ctaataaggc tgatttttct actgacacga tttatcaaat
    33961 tgtcaccgat cgttttcatg atggtaatgc tgctaataat ggaaatacag atgtatttga
    34021 taaaaatgat cctaaaaaat atcatggggg tgattgggca ggtatcatta agaaactaga
    34081 agatggctac ttaaccaatt taggggtatc agctatctgg atttcatcac cagttgaaaa
    34141 cattgatacc attgaccctt caaatggcag tgcagcctat catggctact gggcaaagga
    34201 ttttttcaaa gcaaacagtc actttggaac aatggaggat tttaaaaagc tcattcaggt
    34261 ggcacatggc aaaaacatta aagtagttat tgattttgct cctaatcata cctcaacagc
    34321 agaatataat ggcttaacct tccctgagga cggtgcttta tataaggacg gccagctggt
    34381 tggtaaattc agtcatgatg atcaaaagat tttcaatcat gaatcatgga ctgatttttc
    34441 aacttatgaa aatagcattt atcattccat gtatggcttg gcagacttga acaatctgaa
    34501 tccaacagtt gacgattatc tcaaagaggc tattgataaa tggttagaaa tgggcattga
    34561 tggtattcgt gtagatgcgg tcaagcatat gtcacaaggc tggcaaaaaa attggttgag
    34621 tcatatctat gagaagcata atgtattcgc ctttggggaa tggtttgctg acggttcttt
    34681 taatgatcca ttgatgacta aatttgctga tactagcggc atgagcctgc ttgattttag
    34741 gtttgctaat tctgttaggc gcctgtattc tgatttatca gcgaaaatgc aagattttta
    34801 caatatgatt gtagctacgg aaaaagagta caaggaagtt tcagatcaag tgactttcat
    34861 tgataaccat gatatgaccc gctttgctac tctagtcaat cataatcaga cagctgttaa
    34921 tcaagcctat gctttactgc taacatcgcg tggtgttccg aatctttatt atggttcaga
    34981 gcagtatgct acaggtgcta acgaccctga aaatcgtggt gatatgccaa cctttgataa
    35041 gaattccact gcttatcagg tgattagcaa actagcacca ctgcgtaaga aaaatcaagc
    35101 cctggcttat ggtacaacac agcagcgctg gattaatgat caggtcttgg tctttgaaag
    35161 aaaatttgga aatgacgttg ctttagtggc tgttaataag gatcaaacaa atggctacac
    35221 aattagtggc gctaaaacgg ctttaccagc tggtaagtat gctgatgaat taggtggctt
    35281 actgggcgga aaggaattaa cggtatcagc tgatggtaat gttgaggcat ttgagttagg
    35341 tgcgggtcag gttgcagttt ggacctttaa agggcaacat gagacaccgc agataggaga
    35401 cgtagacgct tcgtttggcg ttgcaggaaa tactgtctct atttcagggc aaggatttgg
    35461 tagtgctcaa ggtcagcttc attttggtga tagcaaagca gatattgtgt catgggacga
    35521 taccttgatt caatttaaga tacctgctgt agctgctggg aaccatgata ttaaggtgac
    35581 cacatctaca ggacaaagca gtagccctta caaagccttt gaagtgttaa cagataagca
    35641 aattccagta agattggtgg tcaataattt caacactgta ttaggtgagc agctttatat
    35701 cgttggtgat gtggttgagc ttggggcaaa tgataatcat aaagctttag ggcctatttt
    35761 taatgcaaca cagtcaattg cgcagtaccc aaattggttc tatgatgtca atctgcctat
    35821 taacaaaacc attaactgtc atcttgtaaa gaaggatagt tctggtaaag tattgtggac
    35881 tagtccagaa acctatacca ttaaaactga tagcaaggct caaaccattt cattgaaaaa
    35941 atagttgcgt tatctgtgat gttatttaat actctatgaa ggaggagaac cataaaaggg
    36001 tgatagagag gaatgacaaa tgcttaagaa tgaaaaaatg aagaatccac aaaaagccat
    36061 gtggctttca ataatccctg gtctggggca actctacaat actcaaaagg taaaaggctt
    36121 tattttgctt cttgtgtttt taggtgagct gctagaggct ttctttgttg gtattccggc
    36181 tcttgctggc ttgtacagcc ttggtagtgt accaatggag gatcattccc tattcttatt
    36241 gattaaggga gctatgcagc ttatcctatt tgccttgttt ttgatctttc atttggctgc
    36301 tatgcgagat gctagactag tggcaaggga gatcaatgca ggccatagca tttcattaac
    36361 cttaaaggag atggtacaat ccatctatga aaagggcttt ccttatttgc tgattattcc
    36421 agcctacttg gccatggcct ttgccattgt ttttccggtg cttgttactt tattaattgc
    36481 atttacaaac tatgatttta ggcatattcc tccctataaa ttattagatt gggttggcat
    36541 taagaatttt aaaagcattt tagagcttag cacctttaag tcagcctttg gctctgtgct
    36601 gtcatggacc ttgatttgga ccttggcggc aacgagtctc cagattgtga taggaatagc
    36661 gactgctatt attgccaacc agtcctttgt gaagtgcagg cgcatttttg gggtgatttt
    36721 cttgctgcct tggggggtgc ctgcttttat ctcgatcatg agctttggta atttctttaa
    36781 tgattctatc ggtgctatga atgttcaggt cttaccattt ttagaaaagt ttgtgccatt
    36841 tgcagatttt gggattatcc catggaagac agatcctttt tggacaaagg ttgcggtgat
    36901 tatggttcag ggctggctgg gctttcctta tatttatatt ttggtgtctg gtattttaca
    36961 atcaattcct gctgatttgt atgaggcagc aacggttgat ggtgcaacag ccctgcagaa
    37021 gtttcgccaa attaccttgc caatgatctt tgctgtcgca gccccgacct taatctcgca
    37081 gtataccttt aattttaata acttctccat tatttatctc tttaataatg gaggtcctgg
    37141 tacagttggc ggtggcgcag ggtcgacaga tattttgatt tcttggattt acaagctgac
    37201 cacacaaacg tcaccacagt tttccattgc ttcagcggtg accttaatca tttccttgat
    37261 tgttatttct gtatcattga taacctttaa aaaattcaaa gcctttgaca tggaggatcg
    37321 ctaaatgggt aggaattatt tgccacagtc agtgaagaag aagcgcttgt tagctcagct
    37381 gttgacttac agctatttgc taatcctgtc gatcatcatc ttatttccaa tcttggtgac
    37441 cgttagctca gcctttaggc caggaaatac aactgccttt agctttcata ttgatgggcc
    37501 ttggacctta tcaaactttg agacactctt tcaggacacc tattacttaa gatggtactg
    37561 gaacacgtta gttgtcgcct ttttcacgat gctgatccag gtgacagtca ttacgctgac
    37621 aggctatgct tacagccgtt atcacttttt tgggcgtcaa aagagtttgg tctttttctt
    37681 agtggttcag atggttccga caatggctgc cttaacagct tattttgtga tggcttggtt
    37741 gtttaatgct ctgaatcact attggttcct cattctgatt tatgttggag gaggcattcc
    37801 gatgaatgct tggttgatga aggggtattt tgatactgtg ccttatgatt tagatgagtc
    37861 agctaagcta gatggctctg gtcactttag gaccttctac caaattgtat ttcctctggt
    37921 tcgtcctatg gttgctgttc aggccctatg ggcctttatg gggccatttg gtgactttat
    37981 gcttgctaag tttctcttgc gtgaacagga gcattacacc gtagcggtag gtcttcagtc
    38041 attcatcact aacgacgcta gggatcctaa ggtcacattg tttgcagccg gggccatttt
    38101 aattgcagtg ccaatttcag tgctattctt ctttttacag aagcattttg tttcaggctt
    38161 aaccaatggt ggaacaaagg gttaatttat ctttcaagga gcctttatca tgactaatga
    38221 tcgatttcct atttcttaca caaccattat tttttctcct aaaatgatat ttgctcgttg
    38281 cagtgccttt ttgtggtggc agaatgtgat tttagtgatc tttctaaatg ctctggtgtt
    38341 aatgccgatc acgctgcatt atgcaagctt gaagagctat cccttagagc acatagttag
    38401 taatggttta gactccttga cagaaaaaac ctatcatgcc ttgacacaag gcactatttg
    38461 gcatgatcgc tatgatggaa aaacagtcct tatagaggat actgatgctg ttgttgctgt
    38521 attgccaaca ccagaaatag tagaagagct aaagaaagat caaagaagcc agctgatatt
    38581 aacagaaacc tcatggattt taagctttcc tgatggtcaa aggctaactg ctaaggttaa
    38641 aggcaacaag gaaaggctaa cgcgcttaac ctctctagag gctgtcaagg cctttgttaa
    38701 tcagcaatgg tacaatagca atcgtgccgc tgtgcttgcc tttttgctgc tagtggctag
    38761 cagtgtggtc tatctaggag ccggtttagt gatcggaatt ggctcgttat cactgttatt
    38821 aacaagatct gctagattat tttcactcaa gagctactca gaatgcttgg gtttgctagt
    38881 gaattgcttt ggacttccta cgcttttagc agtgcttata agtttttggg tgcacaatcc
    38941 tattgttatc atgaatagtc aggtctttgg cacactgctc atgctggttc tagtctttta
    39001 caaaactcag tttagagatg aggagcaagc actagcttag cccttgctga catcaaaaaa
    39061 tccctccc
//
LOCUS       DARYUW010000015        38048 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYUW010000015 DARYUW010000000
VERSION     DARYUW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38048
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(80..1285)
                     /locus_tag="TVW11_000657"
     CDS             complement(80..1285)
                     /locus_tag="TVW11_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1364784.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TVW11_000658"
     CDS             complement(1538..2791)
                     /locus_tag="TVW11_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1364785.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TVW11_000659"
     CDS             complement(3188..3808)
                     /locus_tag="TVW11_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364786.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TVW11_000660"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TVW11_000660"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TVW11_000661"
     CDS             4121..5347
                     /locus_tag="TVW11_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1364787.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TVW11_000662"
     CDS             complement(5457..5951)
                     /locus_tag="TVW11_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1364788.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TVW11_000663"
     CDS             complement(5948..6730)
                     /locus_tag="TVW11_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1364789.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TVW11_000664"
     CDS             complement(6829..7368)
                     /locus_tag="TVW11_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1364790.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TVW11_000665"
     CDS             complement(7372..7683)
                     /locus_tag="TVW11_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364791.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TVW11_000666"
     CDS             complement(8070..8207)
                     /locus_tag="TVW11_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1364792.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TVW11_000667"
     CDS             complement(8591..9835)
                     /locus_tag="TVW11_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1364793.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TVW11_000668"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TVW11_000668"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1364794.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TVW11_000669"
     CDS             11812..12657
                     /locus_tag="TVW11_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1364795.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TVW11_000670"
     CDS             complement(12853..16815)
                     /locus_tag="TVW11_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1364796.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18776)
                     /locus_tag="TVW11_000671"
     CDS             complement(16950..18776)
                     /locus_tag="TVW11_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1364797.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKA
                     ADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19136..19609)
                     /gene="perR"
                     /locus_tag="TVW11_000672"
     CDS             complement(19136..19609)
                     /gene="perR"
                     /locus_tag="TVW11_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1364798.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19646..20098)
                     /locus_tag="TVW11_000673"
     CDS             complement(19646..20098)
                     /locus_tag="TVW11_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1364799.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20338..22980)
                     /gene="polA"
                     /locus_tag="TVW11_000674"
     CDS             complement(20338..22980)
                     /gene="polA"
                     /locus_tag="TVW11_000674"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1364800.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23404..25134)
                     /locus_tag="TVW11_000675"
     CDS             complement(23404..25134)
                     /locus_tag="TVW11_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1364801.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25152..26348)
                     /locus_tag="TVW11_000676"
     CDS             complement(25152..26348)
                     /locus_tag="TVW11_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1364802.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26548..26790)
                     /locus_tag="TVW11_000677"
     CDS             complement(26548..26790)
                     /locus_tag="TVW11_000677"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364803.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26855..27946)
                     /gene="ulaG"
                     /locus_tag="TVW11_000678"
     CDS             complement(26855..27946)
                     /gene="ulaG"
                     /locus_tag="TVW11_000678"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1364804.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28141..29787)
                     /locus_tag="TVW11_000679"
     CDS             complement(28141..29787)
                     /locus_tag="TVW11_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1364805.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30091..30807)
                     /locus_tag="TVW11_000680"
     CDS             complement(30091..30807)
                     /locus_tag="TVW11_000680"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1364806.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30807..31670)
                     /locus_tag="TVW11_000681"
     CDS             complement(30807..31670)
                     /locus_tag="TVW11_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1364807.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31675..32340)
                     /locus_tag="TVW11_000682"
     CDS             complement(31675..32340)
                     /locus_tag="TVW11_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1364808.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32435..32920)
                     /locus_tag="TVW11_000683"
     CDS             complement(32435..32920)
                     /locus_tag="TVW11_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1364809.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33136..33414)
                     /locus_tag="TVW11_000684"
     CDS             complement(33136..33414)
                     /locus_tag="TVW11_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1364810.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33529..34962)
                     /locus_tag="TVW11_000685"
     CDS             complement(33529..34962)
                     /locus_tag="TVW11_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1364811.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35445..36065)
                     /locus_tag="TVW11_000686"
                     /pseudo
     CDS             complement(35445..36065)
                     /locus_tag="TVW11_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36067..36684)
                     /locus_tag="TVW11_000687"
     CDS             complement(36067..36684)
                     /locus_tag="TVW11_000687"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364812.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36671..37459)
                     /locus_tag="TVW11_000688"
     CDS             complement(36671..37459)
                     /locus_tag="TVW11_000688"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364813.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37530..37931)
                     /locus_tag="TVW11_000689"
     CDS             complement(37530..37931)
                     /locus_tag="TVW11_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364814.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        10984 a         8909 c         7423 g        10732 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgctcctc tcttgcgctt
     2821 tgtattttgc ctttaaacac taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaag caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc taaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatca cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tgggtctact ggatccactg ggtctaccgg atccactggg
    17281 tctaccggat ctactgggtc taccggatcc actgggtcta ctggatctac tggatcgacc
    17341 ggtttagcaa ccaaggctgc cttggcatct gagagggatt tcttagcatt taacacctta
    17401 accaagctgt tagtaatagc tgtcggttct gtctcctgag cataagctgt ctcacccgct
    17461 gctgcgacct ccttagcctt agctagctgg tctgtatagg cttgagcaga agctgctgta
    17521 tatggagata ggtctagatt ttctccgata agagcattta attggtctaa agcagaacgc
    17581 aattttgcct ttccttcttc ggcaatcgca gcctttacct ttaaaatagt atcaacaact
    17641 gaatttgttt ctgtagtgta gcgctctagc tcataaaggg aaatgtcttt tctctcttta
    17701 tccttgttaa cagttctata gaaggtacct gctgcttcaa tggccttatt gtacaattcc
    17761 ttcaaagact ctgatgtcaa agcaagattt ggattttctc ggtaaagctc taacagctta
    17821 gccaaggctt gatctaaggc ttcatgcgct acagcagtct taagcgtcgt aagagcttgc
    17881 gttaaatcag tcgcagcctt atcaacatct ccttgtgaag gaccaaatga attttgaagc
    17941 ttagctgccg ctgcaagctt ttgcacaaga ccgtcatacg cttctttagg atactctttg
    18001 ccatctgtta taaaaggtgt agcttgatta atagcttcat ttaaagcatt aagattaaca
    18061 agactagtaa tagcggaatc aatagtagta acagattgat ctactgtatt ttgatcaggg
    18121 tcactgttta aataggtctt accaatagta accgctgatt gcaaggcttg cagtgattca
    18181 tcagaatacg ttccttcagg ctggctgagt tttagcttag cctcctctaa cgacttcctt
    18241 aactcagttt tattgctgtt ggaatttttt agtttaaatg tgaagagctt tttggtatca
    18301 tttttcccat agaataccca agctttaata gtataagatc cccccggtac agcatatgta
    18361 ggcgaagcta acatttcatc agttaaaaag gaagtacccg cagcattgta aaagtcaaac
    18421 catattttta ctccaggggt atcaattcct cttgaaccat ctccattcga aataaagtca
    18481 aaagtatctc catcattaac agtcccatta ctacctttac gagtaaccgt aatttgactc
    18541 ataagatctg agatagtaat tggttctcct aattcaactg tatattcttg tggaatatct
    18601 atgtgccagt tcagatgttg acctgtccca ttattttcaa atgcactagc agtagtcgtt
    18661 tccgccccta ctgttaaagc gctatcaata ttatccgaca aggcaaccaa tcctgtgctg
    18721 aaaactaatc caacaagacc acagccctta agacaccgtt tcgtgaattt cttcattctt
    18781 ctttttcctt ttctagagcc ctagcaggct cgaacaatag caatatgtgt catagggcag
    18841 ctgctatcac tagtagctgc cactttgata ttagcctgat tgtgacactc aaatatcact
    18901 tataatttac aaaaaatttt aagaaaagtc aatatacaaa cggtttttgt taaatttttt
    18961 aaaaatataa caaaaaacaa gcacgccaat ctggtctata acagttttta ttgtcaatag
    19021 tgatcgctaa agggtttttc agccaacaaa aaaagagtga gtccctaact ctctcttcta
    19081 gactttgtgc catatcatca gctacacgaa cagccaagat caaaaaggcc agctctcaat
    19141 agtctgtgtc cttaccctgc ttcgtctgac agctagggca aacaccatag gctataactg
    19201 gaatacgggt gaccttatag cctgtttgct ggtgtgcttc cttagcgata tccatcacat
    19261 ctacgtccat aaaatcagcg attgtcccgc aaacctcaca aaccacattg acatgctgat
    19321 gtcccataaa gtcataatag gtcgtcaaat cattactaat tttcagctcg gatacaaagc
    19381 cctcatcaac gagaaccttc aaattattat acaccgtagc aaggctcata ttagggtatt
    19441 gaggctgtaa atcacgatag attttatctg cgctggggtg ctcagtggac tgaatcatgt
    19501 aagaaatgat cgccttacgc gtctcggtaa tacgaatatg cttgtcacgt agatgctcta
    19561 ggacattttc ataggcattt agagcttgct gatgtgaatg aatgtccaag cttacaacct
    19621 cctccttttg taactatggc actaactagc aggaatcttg atcctgcttg ctgattagcc
    19681 gtaaatagtc aatcttgata cagcgattca taacaatgtc agctttgcct gctgatcgca
    19741 aaagctcctc agcttcttgg ctatacaagc caagctgtgc ccaaaagacc tgaccctgac
    19801 aagctaaaaa gtcctgagca acctgaggca aatactcact tcgtcgaaag acattggcaa
    19861 tatctacctt aaaaggaata gccgcaaggc tagcataaac gacctctcct aaaacagact
    19921 gacctgccag cctaggattg acagggacaa tccgatagcc cttagcctgc ataaacctag
    19981 ccacatcata agcagcagtg gtttgacgat cagataagcc aaccactgca atggtcttgg
    20041 aagattcaag ataagaggtg atagtctcat cagagggatt ttgaaatgta tcaatcatca
    20101 tttacttcct ttttatcaag cacacccaat agcaaatcaa caacaggaaa agacaatcgc
    20161 tgccggtatg acatagccaa ccatctggct accaagctca aggaaaaccc tccttagcat
    20221 gacatgccct gctgtttttt tctcttcatt atagcataag tttttaaaat gcggaacaca
    20281 aggaataaca gcagccacac caagcaggct gccacttaac accactgcta atctagtcta
    20341 cttggcctca taccagctct tgccggcact ttcgtctaca cgcagcggaa ctgccaggct
    20401 gacagctgat tccatcgttt ctttgaccag cgctttaaca gccgctagct catgattagg
    20461 cacctcaagc acaatctcat catgcacctg aagcagcatt ttggtctcaa agccaccagc
    20521 tactagggct tggtcaagat ttatcatcgc aattttgaga atatcggctg cactgccttg
    20581 aatgggcgaa ttaatggctg tacgctctgc aaaggagcga acgttgaact gacgagaatt
    20641 gatatctggc aattgacgac ggcgcttaaa gagcgtctca acatagccct tatccttggc
    20701 ttcacgcaca accctttcca tgtaagcctt gataccaggg tagcgctcaa agtaggtgtc
    20761 aatataagcc ttggcctgtt ttcttggaat tccaaggtta ttagacaagc caaagtcaga
    20821 aatcccatac acaatgccaa agttaacagc cttagcattc cgacgatcat tggcagtgac
    20881 gtcctctggc ttttcaatgc caaagacacg cattgccgtt gaggtatgga tatccgctcc
    20941 ctccttaaaa gcagcaatca aatgctcatc tcctgaaata tgtgctaaaa cacgcaattc
    21001 aatttgcgaa taatccgagc taagcaaaac agcatcatca tgagatggag taaaggcctt
    21061 acgaatcaag cgcccctgct ccagacgaat cgggatattt tgcaggttag gatcaacact
    21121 ggaaagtcgg cctgtctggg ttaaatcctg taaatagcgg gtgtggatcc tgccatcagc
    21181 catgatgtaa tcctgcagtc caatcacata ggttgattgc agcttagtaa tttgacgata
    21241 gtccaagatc ttagccacga ttggcgcaat tggcgctaag cgctccaaga catcaacagc
    21301 cgttgaatag cctgtcttgg ttttctttgt caaatgaaga gggagctgca ttttctcaaa
    21361 gagtatcact cctagctgct tgggagaatt aatattaaag acctcaccag ccatttcata
    21421 gatttcctgt gtcagttcct caatgaccac cttattttgc tctgccattt cctgcaggct
    21481 atcttgattg acagcaatgc cttcgatttc cattttcgca aggacattgg caagcggcag
    21541 ttcaatgtca gtgtagagat cagcctgctc atgctctgcc agcttatcaa gcatgactgg
    21601 tctactatcc agcaagacct gaaccttacg cgccagatgt cctaacaaaa cagccttgtc
    21661 aggcacagca cgcttgaccc ccttaccata gacaacctca tctgtatcca gtgatatagt
    21721 ggtataaaga cgtgccagag tagccatctc attgtcctct acagttgaca agaggtaatt
    21781 agctaagcgg gcatcatagc tggcagccgg caaatcaagc cccagatgac taagcagaac
    21841 cttactgcgc ttaaaatcat aggtagcaat cggctgctca agaacctttt taaagagctt
    21901 tgtagtgagg agactaatat ctgctgaagc ataaatctgg ccttggttgc cccaagcaaa
    21961 gccaatcagc tcctcgcggt gataattatc cctcaaagct tcaaaataaa acaccgtatc
    22021 gtctgaaaac atgtccgctc ttatgtcagt aacttcctga taagcaatct cagctaccgg
    22081 ctcctgtggc aactgactag ctaaggcatt ttttagttga acaaaatcca tctcatcata
    22141 aaattgtgac aagcgatcta gatctggacc ctgatagaca atatcctcca atccaatcgt
    22201 aatcggagcg ctagtgttga tagtagcaag tgtctttgag aggaaggcct gctccttatc
    22261 atgaagcagg ttttccttca tttttgaagg cttgaagcta tcaatatgct cgtaaatccc
    22321 ctccaagctt ccatattcgt gcaggagctt tagacctgtt ttttccccaa ttttggtcac
    22381 tcctggaata ttatcagact tgtctcccat gagcgctttc aagtcaatga attgctctgg
    22441 cgtaagcccc attttgtcca taaggtaggc tggggtaaac tcttcaaatt cagcaactcc
    22501 ttttttagaa atctcaacaa cggtatttgc atctgtcagc tgaatcaaat ccttgtcacc
    22561 actgacaata gtcacatcaa aaggaatctc tgtacgctct gccattttat caagcgttcc
    22621 gataatatcg tctgcctcgt aatgctctag ctcataaaag gcaataccaa gcgctcccag
    22681 catatcacga atataaggaa actgctcccg aaattcatca ggggtcttgg cacgtcctgc
    22741 cttgtaatca gcaaaaagct ctgtccgaaa ggttgtttta cccgcgtcaa aggccaccaa
    22801 gacatgcgtc ggctgaacac gcttcatcat gtggtctagc atcaaatgaa agccataaat
    22861 cgcattagtg tgaagaccgc tgtgattttt aaagcggtca atctggttat agagggcaaa
    22921 aaaggcacga aaggccactg aggagccatc aatcaaaagt aatttattct tgttttccat
    22981 gcctttatta taccacacag tgacctgctt tgctctgacc agctacgctt tttgcaagca
    23041 ctagcaggta aagcagcata cccgtagctt gatcaaaaga tccaagctgc ttgaaggaag
    23101 ataaatgact gcttttgctt tatcatcaag acatttctac caaaaaagag actgagataa
    23161 aaagagtgac actttagaga gtcttaacta atatcctttg ttatctaatt cattaacaaa
    23221 cgaacaggcc tagttttcaa aacctcagaa aactaaacct gttcatttgt tctatttgaa
    23281 gtcagacttt gtctcaatct ccaaattgat gacatcatct gctatgactt tcctaagctg
    23341 atatggacgg aaagccttct gcaaaatcca tgattagtct aggctacatt tgagcgagcg
    23401 gccttatgac tgagtccatt tggccacctt atcagcatgg ctagccaccc atttcttggc
    23461 tgcggcttct ggtgtcatgc cctgattgat gtcaagcata acagcctcca tatcctcttt
    23521 ttcccaatgg aagtgatcaa caatcctatg aacagctggc aggtcggcct ttaagccccg
    23581 acgtgcaatg gtattgatat tttcctttga gccaaaggtt ttctttggat ctgccaggta
    23641 tttcaaatcg tacttagcaa acatccaatg aggagaccaa gccgtcacaa cgatcggctc
    23701 ctttttcttg accgcctgat caagtgaggt ggtcatagca cctgtcgaag cagcaacgag
    23761 ctcccaatct gccaagttgg aataggcctt ttgcgtctta tcagcagcag tcataatacc
    23821 agctcccggt tcaatcccaa taatctgttg attggcttga tccgaaagct cctctatgct
    23881 gttcacatcg ctcatatagg ctggcacagc gagtcctagc tttgttccct tcagattagg
    23941 accaagatta tccagcttat cctgatactt ttggtactgc tgctgatggg tcactggtaa
    24001 ccaggcactt gttgaaaagt ctgcatcgcc atttgcgatg gtttgccaca tcacagcatt
    24061 atccagtggt gtcaaggtta cctgataacc ctcatctctt aagacctgag cgataacatg
    24121 ggtagaagcc acctcagaat cccactgcac ataagcaatg gtcaccttct gccccttgtc
    24181 tgctgagctt gataacatcg cagcaaagcc acgccccaaa gctgacaaca aaaagacagc
    24241 taaagcagct agaccaagcc atttcttggt ttttccagtc tgcgttcttt cttgcggctt
    24301 accgttaaaa tgctgagtca tacgatccaa aataatcgcc aagataacaa gggccaaacc
    24361 actaacaaag ccacgcccaa tatcagcatg ctgcaaggcc gataggacct cacgtccaag
    24421 acctggagca ccaatcattg agcctgtcac aaccattgat agggccaaca tcatggtctg
    24481 attaacacct gccatcatcg tatgctttgc caagggtaat tcgaccttca gtaatttttg
    24541 tttaggggtt gacccaaagg catctgaagc ttcaaccaat tctgtcggaa tatgacgaag
    24601 cgctaaattg gtaaaacgaa cagtcggcgg caaggcaaag ataaccgacg caaagacgcc
    24661 agggaccata ccaatgccaa aaaaggcgac agccggaatc aaataaacaa aggctggcat
    24721 ggtctgcata aggtccagca ttggattaat cacctggtga acaatcttat ttttagccat
    24781 ccaaatgccc aagggaatac caagcaagac agagatgagg cttgctacca aaaccagcgt
    24841 aaaggtattg atcagctctg cccacaggcc ttggttatag acaaataaca ggcccaggag
    24901 ggtaaagatc ggcaaaggcc atttttttct tgccaagaaa aacatcgcac aggtaaccaa
    24961 tagcataaac agtaacggat tgataaacaa aagggtctgc gtgatccaat ccatcaaagc
    25021 attgcccaca agctgcagca gatcaaagaa gcctgaaaag gtttttgtca gccactcagt
    25081 tagttgctca accagctgtg ccactggtag agttgtttgt aataggtttt ccaaaataca
    25141 gtctctccat tctaattaag gtcgtcatct ggaatattag ccaaggcttc aaggacacgc
    25201 ccacgaataa taacccctaa caagcggtgc tgctcatctg tcactgcaat tggcgcagaa
    25261 gagtcataaa tcaagggcaa aatatccgta ataacagtat cctttgagac cgttctgaca
    25321 ttacgatcaa taacctctga caaggggagc tttttctgac gtgcttcaat cgctccgtct
    25381 gctgttaggc ttcctattag ctgacgacga cgattggttg ccatgagcat agacacctcc
    25441 tcattgtgca tacgattcaa agccacctgc ggaccgtcca gatcaaccgt tgttgtgata
    25501 ggcttaatca taatatgctg agcagtcagc acctttgagc ggtcaacgtc ctctacaaat
    25561 tcacgaacaa aatcattagc cggattggtt agaatatcct cacccgtccc aatctgcatg
    25621 atctgaccgt ccttcatcaa ggcaatacga tcaccaatac gcagagcctc attcaagtcg
    25681 tgactgataa aaataatggt ctgcttcatc gtctcctgta attctagcag ctcatcttgc
    25741 atgtcacgac gaatcaaggg atctaaggca gaaaaagcct cgtccatcag caaaatctta
    25801 gggctgtttg ccaaggcacg cgccaagcca acacgctgct gcatgccacc agacaattga
    25861 tcagggtatt ggtccctgac ctcaagaagc cctgactgat caagcgcacg ctttgcaatc
    25921 tctcgacgct cctgctttgg taccccacgc agctccaagc caaactctgt gttttccaaa
    25981 atcgtcttgt gtggaaaaag agcaaagctt tgaaaaacca tattcatatc atgcctgcga
    26041 acttctctga gctgatccac agacagttta gaaatatccc ttccctctaa taaaatagag
    26101 cctgctgagg gctcaattaa tcgattaagc atacgaacaa gcgttgattt gccgctgcct
    26161 gaaaggccca tgatcacaaa aatctcgcct tcctgaacct caaagctggc atcatagacc
    26221 ccgacagtaa ctcctgtctt tttaaaaata gcgctcttac ttttaccagc cttgatcatt
    26281 tcaagagctg ctttttgttt tttgccaaac aatttactca aatgcctgac ctctaaaata
    26341 gttcccattc ttttcctctc ttgttctctt cctcgattaa agctaaatta gcttaataga
    26401 tttctaaaag tgccaccaca attttaaaat aatgaggtca ctttttgctt aaaaaaaaga
    26461 gtctgcctaa acagaacaca ttaattatat aatatatggt cactttttgt caagctggac
    26521 gcttgctacc caagtatcag gatcgtccta agcagtgata tcactagtca accaagcact
    26581 taacagccct gaacagacca cagcaagcag gcctttctga cacttagcgc cttgagagct
    26641 tacccagcag cctcctctag ctgacttgat tgacctatct gactcttgtc ctgcaaccaa
    26701 accaatgctt agactgccaa gcaagctccc aatagcaata agatctgcta agcaaagcgt
    26761 tagcttgctt tgaccatagc tgctagtcat gtctaatagc actctagata aatcaaaagc
    26821 cccacctagc aaggctagat gaggcaaaat aggtttagag aagggcttta aactgaatat
    26881 ttgagtcttc caagaagcag tcgtcaaagc cacgtgggtg atgatactcg atgcgatcct
    26941 gatcctgtgg ataggtgtat ttgccaccaa cctcccaaat gaatggatgg aattggtatt
    27001 gcaagcgctc cttacgcatc ttccaaagct ctaggatttc atcagttgag gccatgaagt
    27061 ttgaccagat atcatagtga accggaatga caaccttggc gcggagattt tctgccatac
    27121 gaagtaggtc aacagaggtc atcttatcct gaataccgat tggattttca ccataattgt
    27181 tcaagacaac atcaatatcg tagtcacgtc catgcttagc aaaatagttt gagaagtggg
    27241 agtctgcacc atgatagatg gttcctcctg gtgtttcaaa aatgtagtta acggttttgc
    27301 gagctaactc ttcgtcagtc actggaagtc ctgctagctc gccaccattt tcctcagcgc
    27361 cagcaactgg taaggtaacg atacaggtac ggtcaaagga ttcaacagca gtaaccttga
    27421 tatccttgaa tgcaaagcta tcgcctggtt ttaccacgat gatacgatcc tttggaacac
    27481 cccagctctc ccaaatcttg ccgcactcat aagggccaac aaatttgaca tggtcaagct
    27541 ttggattgtt gataatggct gctgcagtat tgatatcaat gtggtcacta tgataatgag
    27601 acaccaagta atagtctaac tcattaatca taaagggatc aataaccatt ggctgagctc
    27661 ttagatttgg ttgtagcttg cgaacccctg ccatattggc catttggtga ccacgaacca
    27721 tgtcttttac ttttttagtt gcctttccac gattggacca taggtccatg acaacattgg
    27781 caccacccgg tgttttgatc cagataccgc agttacctag ccaccacata gagaaatttc
    27841 cttcaggcac tacctcttct tcaatttctt cgtttagcca ggttccccat tctgggaagg
    27901 tgctaagaat ccatgattca cgagttatat cttgtacttt agccattatg tttcctccaa
    27961 aatgaatttt tatctatact ctaagtatag accttcttta ttctcataaa aagaccaagt
    28021 gtcacacact cttgtgttca aaactggact gaattttggc tcaaaataaa ctaaaagccc
    28081 cagccttctc ctaaaccaat agacagctga ggggtcctta tcaataggca agctagtagc
    28141 ttacaataat tcgtgatgaa tgagcttttc aatttttgtt ttcaaggcat agcggtcagc
    28201 atcgtcctta acaatggtct cgatcgcctt ttctagctca agggaaaaac gagagctatc
    28261 actcaagcgc ccctgctttg aaaaacggat caatctaata atgtcatcat cgctcaaaat
    28321 aggattgaca atcagtacgg gaacaagagc ctccagtgcg tctgttgttg ataccacaat
    28381 gtcaacagac atcaaatcaa agacactctg gtattgctct gttgtaaaga cagcctcgat
    28441 ttgacaattg ggcaaataac gctggcactg cttcaacagc agcttttgaa tcccaatgcc
    28501 atcatctgaa acgataacaa gcttggtctt gtcccagtca gcatgactat ggcgcagctc
    28561 tcctcccaga tgaatcgtta gataagccac gtcatcatct gttagacgga tctgccaagc
    28621 ctgctctagg attacagcac aggattgagc catagcaaag agctcctcgt atttttcctt
    28681 aatatggtct gttaaaggat tgatcgaaaa aatcccatag gcctttcgat aaacaagggc
    28741 cttgcaatgc ctggtcagct gtctaagcaa gtcctttttg tgggtaaaat gcagctgata
    28801 gcgcagctcc agctgatcga taaaatcacc aatagtggct cgcatctgct cataatcctg
    28861 actttcaaca tggtgatcct gatcttttct aaaggatagc atcagcatgg ctatcatgcc
    28921 tacctcaatg tcatctaaat gcagcttgaa attgtggtaa agctcactag ccaatgcctt
    28981 agcaatctgg tattccttgc gcttccaaat caggttaaaa tcccttttaa gcgctgtttt
    29041 agtttccgaa tgcaattgca tgttgcgata gctaagcagg ataaaaggaa gaatttgcag
    29101 cataaactga ctatcctgaa tattaattgt tttgcctagg ctagcctgag acaaaaagag
    29161 gtattcgtga aaataatcca aaacctcctt tgaaaaataa gctgacaagc cttgtgtctc
    29221 agaaagctta tgatcaaaaa gctcaataaa gctgctattg cctccctgat aaacacctgc
    29281 caataccttg taaaggtact gaatcaaagc catagggtga cagtcaaagt aatagccctt
    29341 ggccttggtg gcatgcagct gaatcttatt gttatagcta gacaattcct ctctcagttc
    29401 agcaaggtca tttaagatgg tatttctgga aacatcatta atcatcatga gcttatccag
    29461 tgtcacccgc tctgttgcca ctgcaatata aatcgctgat aagctcctgc gctcatcacc
    29521 cttcatgaca tagtgataat ctgccacttc attgaggagc tgttggcagg cagccttttg
    29581 ctcactattt agcaagatgc caacccgagg ataggagaca atttgagcaa catggctggg
    29641 cagcgcttcg ttaattttat ccaaatgata atagattttg cgccgcgact gacccaaggc
    29701 agctgaaatc gccatgactg tctcagcctc cttcaatcga atcagatatg acagcagatc
    29761 atagcttttt ttatccaaaa taatcacgtt catacctccc ttctataaaa catcactacc
    29821 acacagcctt atcagtttac cattttacct atctgtagga aagaatacta ggccaaagtc
    29881 aatttctaaa taggaaaaaa cgaacgatca ttagttttct gaagataaaa ttcctaatta
    29941 gttcgctttt ttcttttata attgtaatag ttgaattaat tattaaactt tgtctaaaat
    30001 aagaggcttt ttatcccaga ttgcaacaag ggttaacacc ttgaccttaa gcctagctaa
    30061 gcagctctca ctaagttact agctgctgcc ttaatgccgg ctaccttttt ggccataata
    30121 ggcatttgga ccatgctttc taaggtaatg cttgtccata atataggttg gagctggctc
    30181 cacacgagga ttgatttgtt ctgtcaggcg gttcatcttg gccacctctt cgagcaccac
    30241 tgagtgataa accgctaatt caggcgtctt gccccaagta aagggaccat gattgcgaac
    30301 aacaatacca ggcactgcca tcggatcaag accacgacta gcaaattcct ctaaaataac
    30361 cgtacccgtt tctttttcat aggctccatt aacctcatcg gcagttagag agcgagcaca
    30421 tggaatgggg ccataaaagt aatcagcatg agttgtccca taaaatggaa tatctcgccc
    30481 agcctgtgcc cagccaaccg cttctgttga gtgtgtgtgc acaatcccgc caacctctgg
    30541 ccatgccttg tataattgca catgggttgg caaatcagaa gaagggttca gctctccctc
    30601 aacaatagtg ccatctaagt ctgtaacgac catattttcc ggtgttaatt ggtcatagtc
    30661 aacgccgctt ggcttgatga cgatacgtcc cagctcacga cagacctctg agacattgcc
    30721 ccaggtaaat ttcaccagcc catgcagcgg tagggccttg ttggctgcac agacacgttc
    30781 acgcatttct tgtagccttt ttgccattag cttaaccccg ctttctcaat cagtggataa
    30841 aggaaatcct gtgcctcctt gatggcagct cttgtctcct ctacagtttc acagttttct
    30901 gaccacattt caatcaaaaa tggaccatga taatgcgttt tcttgagcac atcaaacatt
    30961 gcttcccaat caacacagcc ttgaccgaat ggcacatcac gaaattgccc tttagatgtt
    31021 tctgtcacag cataggtgtc ctttagatgc aaggcagcaa tagaccgatg cccattgtaa
    31081 aattcactcc agaggtcatt atgccaagca gagacattgc ccgtatctgg atagacaaag
    31141 agataagggg agtcaatttc tttttccaca gctaggtatt tctcaattga gttgataaaa
    31201 ggatcgtcca ttatttcaat ggctaaaata acctgagctt cctctgccca agtgcaggcc
    31261 tgtctgagat ttttgataaa gcgcgcacgc gtttcaggtg atttttcttc ataataaacg
    31321 tcatagccag ccaattgaat ggtacgcaca ccaagatcct gtgctagcac aatgcatttt
    31381 ttcattagct ctaatgatgt cgcttctgtt tctggattgc tagagccaag tggataacga
    31441 cgatgaccag agaagcaaat gcttgggata cgaacccctg tttcataaat agccttgaca
    31501 atgtctagtc gctcctgttt actccaatcc aagcgcgcta ggcgagcatc tgattcatcg
    31561 acagacattt ctacaaaatc aaagcctaat acctttgcaa attgcaagcg ttccagccaa
    31621 gtaaaatgct ttggcgttgc tttttcatat ataccaatag gacgcgccat attgttaccc
    31681 ccaaatgcgt cgaatctcgt ctttaaaggc acgtgccgct gctgcaggat cctctgcttc
    31741 agtgatacca cgacctgcaa taaaggtaaa gacattaacc ccttcaaaga gcttgagggt
    31801 attgatatct aagccacccg tcaccgatac acgaaagccc atgtcaatga gggctttgac
    31861 cttgttcaga tctttttcac cccatacttc accagcgagt agggcgtcac gtgattgatg
    31921 gtaaatcgcc tgtgaaatgc ctgcatctag ccacaattgt gcctgttcat aggtccaatc
    31981 accatacagc tcaacctgaa tctcgccacg ttccccacgc tcttctttga tggctttcag
    32041 tgcggctgcc atggttggaa tagtggcaca gcaaatacaa gtcatccagt ccgcaccacg
    32101 cttagcatta ttcttagcaa cagtaccgcc agcgtctgca cacttggtgt ctgctacgat
    32161 gatcttctct ggaaataagc tacgcagcac ctcaaccaat tcgctgccta cttgaagcag
    32221 gcaaactgtc cctgcttcga ttacatcaac ctcgtgacca actgcaacag cagccctgac
    32281 cgccccctgc aaatcagaat gatctaaggc aacctgtaat tttggaatat gtgtcatgat
    32341 tttctaccaa gagcccgtag caccgccttc aatgcttaat agcgagctcc tatcctttct
    32401 gttgtgtttg attcgtttag tgatgatggc ttgtctaaga atccaaatcc aagccctcta
    32461 aataaggact atttttggac tcgtccacca aagccaaaac ctctgctgga gtgtgacagg
    32521 caactaagcg cgaaatagcg tcttccagtt caaaaagggc gacaatctgt ggaatagcaa
    32581 ctgttgtatg aatagaagga tcagttgccg ccaaggttag caataccgaa gcctctttgc
    32641 catctgaaaa ggtcaccggc ttggtcagtg tgataagagc aaaggcattt cgcttgaccc
    32701 ctacaccagc ctctgcgtgt ggcatggcca ttcccggcat aaggacataa tagggcccgt
    32761 acttttctgt tgatgcgata atagcgtcat aatattcaga ggtcaccgcc ccgctgtcaa
    32821 tcaaaggctg aacagctagc ttaaccgctt cctgccagct agctgctgac aagcccaagc
    32881 gaatagagtt gttttcgata aatgcttttt ttaaattcat ataactatcc tttctaaatc
    32941 aaattctttg gccagacact ttttgcctca ctcctatcta gctgataaag agaaagagct
    33001 ggaatctctc ttcacaactc tcactccatc tatccttact gaaagttgat tgctacagct
    33061 tagcttacag ccaagtggct gctcttaggc tcactatcat ttgccatgag cagcactgat
    33121 gtcatcaggg ccgctctaaa gcaccgcctg tagcttggtt ttgatttcat tgtcgtccat
    33181 aagattatct agtccaacca aatgaccctt tgtacgccca tctaattcat gaatcaggtg
    33241 attagaagca accacaatat catagcctga ggcaagtccc tttgcctcac ccactgagca
    33301 agaagcagac tgaatatcag tcaccccaag ctgacgaagt gcgttttcaa ccttcatttt
    33361 aataaccatt gatgacccca tgccattacc gcatgctgta agaaccttaa ccatttattt
    33421 tcctccgaat atatgataat ttgatatgaa tgaagacctg cagaagtata tcgacaaact
    33481 cctaccagcc tgtgctaaaa gacgaataag cagctattat caccttgctt attgtgcttc
    33541 accgcggtag taagcctctt tatccttagc cctagcaaat tgtagctgtg gaatagcaag
    33601 taagaagaca cacaccacca catagcctgc aataccaagg aacttgaaga gataaccaaa
    33661 tggaagccaa ggaagcacca ggtcaatatt gccatgataa ccacctgtca agcccaacag
    33721 accaactgcc actgcaccta aggcaacctg aagaatacct gatataaagg atagagcaac
    33781 agctgccttc cagccaccac gcttatctgc ataaacagca atcgcagcat tatcaaagaa
    33841 gaccggaaca aatcctgtga tgatcaagat tggattttta aagatcacaa gaagtgcaat
    33901 agtgattagc tgaccgataa gcccaaaggt aaatcctgac aaaacagcgt ttgaagagcc
    33961 aaagccatat gacgctgcaa cgtccaccgc aggaaatgaa cccggaagga gcttacttga
    34021 aatcccttgg aaggcattgg tcaactctga cacaaacata cgcacaccct gcatcaggat
    34081 aaagagataa actgagaaag ttaaggaggt ttgcaaaata tacataaaga aggcctgctt
    34141 agctggatta aaggcaccag cacctataag ttctgcatta gacatcatat ctgggccaag
    34201 cacagccaag atagcaccaa agaaaaccag cattagagtg gcagaagcaa ccaccgtatc
    34261 atgaaaaatc gttaaaaagc ttgctagctt aagattgtca aggttctctt cttttttacc
    34321 aaagaaaggc gccaccttgt caacaaacca gatcgcaaac tgctgctggt gcccaatggc
    34381 aaagcctcca ccacctgtca agcgctgagt cgcctcaact gtcatattgg agctgacagc
    34441 ccagtaaagg ccacagataa taccgaccgc ccaagcacca aaagcatttt gaagctgagg
    34501 gattaaaaga agaacaaaca cagagatggt tgccgcctgc tgcaccatga tatgacccgt
    34561 aataaagagc gtacgaacct ttgtcacctt acgaagcgcc actagcaaaa tattgacccc
    34621 aaaaccgatc aaaagggctg tggtggcaac gctgatggat cccatctcct ctagcttggt
    34681 attggctgct gcaagtccaa agtaagggtc aataactgcg gcctttaatt caaatttctt
    34741 acccaatgcc actaggattg ggcgaaaggt gttaaccaag cccccagcac caacattcaa
    34801 aatcagataa ccaaccgttg ccttaacaaa gccagcaaat acttcatgca ggggcttttt
    34861 aagcagcaaa tacccaatca aaaccaaaag acctacaaag aaagccggat tttgcaaaat
    34921 atcttgcgaa aaccagttta ggggagctat aagcattttc ataagaacta cctcttttca
    34981 cagttaataa atatgatatt ttctatacaa taattgtaaa cgatgtaagc gtttaaaaaa
    35041 aagaccaaca atcacacaaa gaagtgttca aaaatgtact gaagccaatt tccagctagc
    35101 tctgatcact gttaaagcac tatcattaat ctctaattaa taaccaaaca catcacaaca
    35161 atatcgggct aacacaaaaa taggccagcc catactgccc agccaaaacg aaacaagcaa
    35221 tcaattcaag gcacttaacc ctgttttata tcgtacaaag cccttttaag atgattttgt
    35281 ttgtttccta atcgtaaatt agttatctga tccgttctct cctcagatat actcaccctt
    35341 atctaattct actgtcaaat agctacttac tcataagcaa atgaatatta agcaaccacc
    35401 aagctacaat aaaagacctt accctgttgg caagatctta ttcattatac aatttttcct
    35461 tctgcgacat ggactacctc atcacacaag tcttcaatat ctgtcttcag atgtgagctt
    35521 aaaatcacaa gcccattttt gctaacatct aaaagcaatt ttttcgtttg ctccacgctc
    35581 ctgtcatcta atgcattcat tggctcatct aatataagga tcttagggtg atgcatcaag
    35641 gcctgaatta accctaattt tttcttagtg cctagcgatt aatgcttaaa tgctgtttga
    35701 ctaaactgat gtaaatgata aacatctaac caaaaagcta aatcaatatc tctagcctta
    35761 ggagagattg acctaagcaa ctctagattt tgtaacaatg ttaaatgtgc aataaactct
    35821 ggattctcaa tcaaaatccc agcatcctcg atataattat ggtactgtct aattttttta
    35881 ttgtcctgat aaacagctcc ttcatctaat ttgatataac cagctaaggc cttaagtatc
    35941 aaggtttttc ccgaaccatt aatacctacc aaaccataga tattaccttc tttaaaagta
    36001 agattaatat catctagaac aaggttaccc ttatacagtt ttctaccatg ttcaatccgt
    36061 aacatctcag ctctccttat aataattgtc ataaagcata tgtaccaata ctattagcag
    36121 caggcaccac caaacatcaa acaaaaagta acgtatcaag gtgagactag caaacaagat
    36181 catagctact acagcagatg aggcatagcg tatcataaca taaatcaagc aaatatctat
    36241 agtaagccaa gataccataa gataacatag tcgttcaata tgatatggtg caccataata
    36301 ggtcatcaat acacctaata ttaaaacgat aaaaagtaac cactctttaa tatagaaaat
    36361 cgtactcgtc cgccatagct tgttaaaaaa taccaactga cttcgagcat gaaaacgaaa
    36421 gatttcctta gttccttcag ccaaatccgc caaaaatgaa atcgtaaaat aaaagctgtt
    36481 gaaggacaag cctagcaagg tgataacctt gacaaaatca gctgtctccc cttcaatcac
    36541 tggaaacggc attagcaacc gatagcacac taaattatga aaatctcgct ccccagtcat
    36601 attagcctta atcaataaaa gatgtattag taagccagta agacatgctt tcattccaac
    36661 aaccagcagg ttagataatt tcatggtgct tcctcaattt taaaacgatg cacacaccca
    36721 ctaagcctaa ataaggtgat aaaaggtaag gaatatcagc atcactataa gatgttgaca
    36781 tcaaagaagt cataagaaca tatttgggag gtaaatagct atataacaac ggtgacaaag
    36841 cccacatcaa aatcaaatag agcatgcttg acttaataaa ggattgaaga tagtcaacaa
    36901 gaaaacaaac gaaatacgta tgaacgaaca aagctaacga ttttactaag caatagtaag
    36961 ctataaaggt tgttgctcct tgaccaaaaa aacgcaatat tgagttttga tcaaaataag
    37021 gcattaaatt accgttcata tgggcaacac catttagcca agacactaaa gtcaaagcaa
    37081 atattacaat gtaaaaactc agtaaaacat ataagctcaa ctgaagcttt aaaaaaatac
    37141 accttttacc atagtcagac tttctgccaa tgaggtattt aagatgtctt gacttaaggt
    37201 aatagtaggc ataggccact aaaatcatca ctagtggata gataaaagat tgataaaaac
    37261 taaaatcaaa caccacacta tccaaacgta tcatactcaa caatagactt ttctttacct
    37321 caattccacc agataaatct actgcacttg tatcaaaaaa taagatatgc ttcaaactgt
    37381 caaaataaat aaaacctaaa aatagtaacg ggactaatgg ataaaaatag cgaaatggaa
    37441 ataatctata ctgtagcatt tatgaataac tcccctacaa aaaatcaagg aaacgcctcg
    37501 ttactaactc aattcacaat tgtagatatt taccaattgt ctggagacca actaccacta
    37561 atggttgttg ctccgtccca ccaattttca cgtaccagat gcaaggcata aaggtaccca
    37621 cttttagtat cctgtgtata aattcctctg tcgcctgtcc aagttttatc tatatcactt
    37681 cttctttgac cgttactatt agctagatag tgccttacca caatttctct attacgtcct
    37741 cttgaatcta aattaacgac ataataaggc gccgcactct tcacaagata atctttcgtc
    37801 cttccaaaag atgacgtgat tctaaaattt tgcaagtaac caatttgtcg ttctgctata
    37861 actaaagaac taatcaataa tgtagaagct acaattgcca ataatccaat cttaattttg
    37921 cctaatttta ttttttaata atttataatt tttatatatt tagcacatca tcagcgcttc
    37981 cttgacaatt gataatacaa ttcatgctag gcttaatcga taaaactaaa tactagatag
    38041 taatcaac
//
LOCUS       DARYUW010000016        36557 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYUW010000016 DARYUW010000000
VERSION     DARYUW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36557
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..693
                     /locus_tag="TVW11_000690"
     CDS             <1..693
                     /locus_tag="TVW11_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364815.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TVW11_000691"
     CDS             complement(1204..2832)
                     /locus_tag="TVW11_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364816.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TVW11_000692"
     CDS             complement(2837..3568)
                     /locus_tag="TVW11_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364817.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TVW11_000693"
     CDS             complement(3605..3862)
                     /locus_tag="TVW11_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1364818.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..5709
                     /locus_tag="TVW11_000694"
     CDS             4234..5709
                     /locus_tag="TVW11_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1364819.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQG
                     PRGEKGEQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGE
                     NGEQQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQ
                     STPSKKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5891..7879)
                     /gene="tkt"
                     /locus_tag="TVW11_000695"
     CDS             complement(5891..7879)
                     /gene="tkt"
                     /locus_tag="TVW11_000695"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1364820.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8263..8907)
                     /gene="fsa"
                     /locus_tag="TVW11_000696"
     CDS             complement(8263..8907)
                     /gene="fsa"
                     /locus_tag="TVW11_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1364821.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGGHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9081..10586)
                     /gene="glpK"
                     /locus_tag="TVW11_000697"
     CDS             complement(9081..10586)
                     /gene="glpK"
                     /locus_tag="TVW11_000697"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1364822.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10926..11519)
                     /locus_tag="TVW11_000698"
     CDS             complement(10926..11519)
                     /locus_tag="TVW11_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1364823.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12187..12387)
                     /locus_tag="TVW11_000699"
     CDS             complement(12187..12387)
                     /locus_tag="TVW11_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1364824.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12446..12601)
                     /locus_tag="TVW11_000700"
     CDS             complement(12446..12601)
                     /locus_tag="TVW11_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1364825.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13107..13973)
                     /gene="rsmI"
                     /locus_tag="TVW11_000701"
     CDS             complement(13107..13973)
                     /gene="rsmI"
                     /locus_tag="TVW11_000701"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1364826.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13978..14301)
                     /gene="yabA"
                     /locus_tag="TVW11_000702"
     CDS             complement(13978..14301)
                     /gene="yabA"
                     /locus_tag="TVW11_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1364827.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14294..15094)
                     /locus_tag="TVW11_000703"
     CDS             complement(14294..15094)
                     /locus_tag="TVW11_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1364828.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15091..15966)
                     /locus_tag="TVW11_000704"
     CDS             complement(15091..15966)
                     /locus_tag="TVW11_000704"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1364829.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15980..16615)
                     /locus_tag="TVW11_000705"
     CDS             complement(15980..16615)
                     /locus_tag="TVW11_000705"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1364830.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16931..17215)
                     /locus_tag="TVW11_000706"
     CDS             complement(16931..17215)
                     /locus_tag="TVW11_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1364831.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17216..17662)
                     /locus_tag="TVW11_000707"
     CDS             complement(17216..17662)
                     /locus_tag="TVW11_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1364832.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17767..18357)
                     /locus_tag="TVW11_000708"
     CDS             complement(17767..18357)
                     /locus_tag="TVW11_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1364833.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18588..19217)
                     /gene="upp"
                     /locus_tag="TVW11_000709"
     CDS             complement(18588..19217)
                     /gene="upp"
                     /locus_tag="TVW11_000709"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1364834.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19367..20998)
                     /locus_tag="TVW11_000710"
     CDS             complement(19367..20998)
                     /locus_tag="TVW11_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1364835.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21084..22529
                     /locus_tag="TVW11_000711"
     CDS             21084..22529
                     /locus_tag="TVW11_000711"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1364836.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22789..23568
                     /locus_tag="TVW11_000712"
     CDS             22789..23568
                     /locus_tag="TVW11_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364837.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23593..24531
                     /locus_tag="TVW11_000713"
     CDS             23593..24531
                     /locus_tag="TVW11_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1364838.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24541..25566
                     /locus_tag="TVW11_000714"
     CDS             24541..25566
                     /locus_tag="TVW11_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1364839.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25563..26561
                     /locus_tag="TVW11_000715"
     CDS             25563..26561
                     /locus_tag="TVW11_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1364840.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26666..27319)
                     /locus_tag="TVW11_000716"
     CDS             complement(26666..27319)
                     /locus_tag="TVW11_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1364841.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27386..28321)
                     /locus_tag="TVW11_000717"
     CDS             complement(27386..28321)
                     /locus_tag="TVW11_000717"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1364842.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28821..29612)
                     /gene="pflA"
                     /locus_tag="TVW11_000718"
     CDS             complement(28821..29612)
                     /gene="pflA"
                     /locus_tag="TVW11_000718"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1364843.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29689..31023)
                     /locus_tag="TVW11_000719"
     CDS             complement(29689..31023)
                     /locus_tag="TVW11_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1364844.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31151..31708)
                     /locus_tag="TVW11_000720"
     CDS             complement(31151..31708)
                     /locus_tag="TVW11_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1364845.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31718..32503)
                     /locus_tag="TVW11_000721"
     CDS             complement(31718..32503)
                     /locus_tag="TVW11_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1364846.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32516..33439)
                     /locus_tag="TVW11_000722"
     CDS             complement(32516..33439)
                     /locus_tag="TVW11_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1364847.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33630..34280)
                     /locus_tag="TVW11_000723"
     CDS             complement(33630..34280)
                     /locus_tag="TVW11_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1364848.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34270..34848)
                     /locus_tag="TVW11_000724"
     CDS             complement(34270..34848)
                     /locus_tag="TVW11_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1364849.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34921..35046)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(35700..35984)
                     /locus_tag="TVW11_000725"
     CDS             complement(35700..35984)
                     /locus_tag="TVW11_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364850.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(36004..36396)
                     /locus_tag="TVW11_000726"
     CDS             complement(36004..36396)
                     /locus_tag="TVW11_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364851.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            complement(36393..>36557)
                     /locus_tag="TVW11_000727"
     CDS             complement(36393..>36557)
                     /locus_tag="TVW11_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364852.1"
                     /translation="VTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAA
                     IDQKLGCDFS"
BASE COUNT        10663 a         8722 c         7267 g         9905 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aagggcgacc aaggtcaacg cggtgaaaaa
     4981 ggcgagcaag gccaacgtgg tgaaaagggc gagcaaggcc aacgtggtga aaagggcgag
     5041 caagggccac gcggtgaaaa aggcgagcaa gggccacgcg gtgaaaaagg cgaccaaggt
     5101 caacgcggcg aaaaaggcga ccaaggtcaa cgtggtgaaa agggcgacca aggtcaacgc
     5161 ggtgaaaaag gcgagcaagg ccaacgtggt gaaaagggcg agcaagggcc acgcggtgaa
     5221 aaaggcgagc aagggccacg cggtgaaaaa ggcgagcaag gtcaacgcgg cgaaaaaggc
     5281 gaccaaggtc agcgcggtga aaaaggcgac caaggtcaac gtggcgaaaa aggcgaccaa
     5341 ggtcaacgcg gtgaaaaagg cgaccaaggt caacgtggcg aaaaaggcga gcaaggtcaa
     5401 cgcggtgaaa atggtgagca acagccaaag ggtgaccaag gaaaggatac caagccatca
     5461 gttccaaagg caccagaatc accaaaaatg ccagagaagc cacaggctcc tgaaaaggct
     5521 cctgcaccga aagctccaaa ggcttcagag cagtcagcta gccctaaggc accagcacct
     5581 cagtcaacac caagcaaaaa agcagtccta ccagctacag gagaggcaag ccatccattc
     5641 tttagtctgg cagctcttag cgtcatcgct agcgcaggtc tgctaaccct aaaaagaaag
     5701 aaaagctaag ccagctattt gacaatagct tctagcaact cgggatagat ctgcaaggct
     5761 gagcagtagc actattaaat ctgaaacaaa aacgcatgac gtcctcccta aaaagggttg
     5821 aacatcatgc gtttttttgt ctaataatgc cgaaagcaag cctagataag gcctgctcca
     5881 gcttaatcac ttatgataag gatttgtaca attcagtagc atgctctact gtaaagccat
     5941 attcttcaaa gatacgattg cccggtgcag aagctcccca tgtatcaatg gtcagtgttt
     6001 tccctgcaag gccaacgtat tttgcccagc caaagcttga gcctgcttca atagctagac
     6061 gttttgtcac tgctgctggt aggatttcct ccttgtagga agctggctgc tcatcaaaga
     6121 tattttgtga tggcattgat accacacgca catggatacc atctgctgca agagcggctt
     6181 gagtatccat tgctagcttg acttcagagc cggttgcaat gataatccca tcaaggtcac
     6241 cctttgcctc tgacaggata taagctccct tattaaggcc atcttctgcc aattccttag
     6301 taccttcaag tacaggaagg ttttgacgtg ttaagacaag cattgtcgga cggtctgtct
     6361 cagcgatcgc acgcttccaa gcagcgtttg tttcattgcc gtcagctgga cgaataacgt
     6421 tcagatttgg cattgatcga acactagcta gctgctcgat tggctcatgg gtcggaccat
     6481 cttcaccaac cgcgatagaa tcatgcgtca tgacataaac cgttggtagc tgctgcaagg
     6541 ctgccatacg aaccgctggc aataggtagt ttgaaaagac aaagaaggtt ccgccataaa
     6601 cacgtgttcc accatgaagg gcaataccgt tcatcgctgc tgccattgca aattcgcgta
     6661 cgccaaacca gatgttacga ccagcataat gacccggctg gaagtctgtc tcagccttaa
     6721 ccatggtatt gttagaggca gaaaggtcag ctgagcctcc ccagaaggct ggcacctgct
     6781 cagagatttg ttggatagcc tgctggctag aaacacgact ggctactgct gtgccaagct
     6841 cgtgagcttg caactcaacc tctgccgcct cattagcaaa ggcttttttg tattcggctg
     6901 ctaactcagg gtatgctgct tcataagctg caaataggtc attccatgcc tgctcagcct
     6961 gctcaccacg cgcctgaagg ccttgtctaa agcgctcagt cacctcttgc ggcacctcaa
     7021 aatcagcatg ggtccattga taagatttct tagcaaaggc aatgccttct gcaccaagcg
     7081 gagccccatg aacagctgaa gttccttgct tttcagcacc aaagccaatg attgtcttta
     7141 cttcaataat ggttggcttt tcagtctctg ccttagcttc ctcgatagct ttagcaatgg
     7201 cctctaggtc gttgccgtct ttaacaagga tatgctgcca gccgtaagct tcaaaacgcc
     7261 ccttgacgtc ttctgtgaag gccattgagg ttgggccatc aagcgaaata tcgtttgaat
     7321 catatagcaa gacaagctta ccaagcttca agtgacctgc cagactggct gcctcctgac
     7381 tgacaccctc cataaggtct ccgtcaccat ttagagcata ggtatagtgg tctacaatat
     7441 caaagccagg tctattgaac ttagctgcta agtgtgcctc tgccatagcc ataccaactg
     7501 cattggcaac tccttgtcct aaaggccctg tggttgcctc aacgccatct gtatgattga
     7561 cctctgggtg acctggtgtt ttagagcccc attgacggaa gttcttaaga tcctcaatag
     7621 acacatcata gcctgctagg tgcaacaggc tgtaaagcat ggcactacca tgacctgctg
     7681 ataggataaa gcggtctcta tttgaccaac ggcggcttgt ctttggattg actgtcataa
     7741 catgattcca tagcacataa gccatcggcg ccgcccccat cggcaaacct ggatgcccag
     7801 aatttgctgc ttgaatagcg tccattgata gagtacgaac agtattaact gccagctgat
     7861 caattgcatc aaatgtcata agtaaaacct ctctgtgtat tacaactaaa aattaaacgt
     7921 tttccattgt ctattgtaac ataaaagtaa actgattttt aacaaaatcc tataaagtcc
     7981 ttaaattctt atctagcaat aagcattgct gttcctagct ttttgtgatt gacagctgtc
     8041 ttagatagag cacctatgct cataagaaaa agcaagccta gctgttgcca gctaagcaag
     8101 cattcctctt tggtacctcc ctttggctac agtaagcgcc agctgcctgt taattctagc
     8161 gcaacagcaa agcaccagct gatcctgcca cctacaaata gctaatccca aactaaccgc
     8221 tacagccaca ttagaatata aggagagctc tatgctctta gcctattttt taaaggaagc
     8281 ccaatcctcc ataaaggtct ttaagccatt tgttgtcaat gggtgctcag tcatcttcgc
     8341 aaataatgga tctggaatgg ttgcaatgtg tccccctagc tgtgcaacag cttcaacatg
     8401 ggcagctgtc cgaatgctgg ctgcgatgat ttctgcttgg aagccataca aatcaatgat
     8461 cccacgcaaa tcactaataa gctgataagg atctgctcca atatcctcta agcgaccaat
     8521 aaatggactg atataggtcg caccagcctt catggccatt agtccctgac taactgtaaa
     8581 aataagcgtc acatttgttt tgatgccttc ttgtgacaag acattagttg cttttaagcc
     8641 ctctgtcgtc atcggaattt tcacgaccac attgtcatgc cacttggcaa tgttcctagc
     8701 ctctgcaatc atttcctctg cggttagtcc ggtgacctct gcactgatag ggccgtccac
     8761 aatctcacag atttccttga taactgtctc aaaatcacga ccctcacgcg agataatgct
     8821 agggtttgtg gtaacaccgt ccacaacacc aagctcatta atcgcacgaa ttgcctctac
     8881 atttgctgtg tctaagaaaa atttcatctt aacctccgtt aattagtctg ttatcagtca
     8941 ttgaacagca tgacgctgtt taccgtctac attatcatta taaaagtcac tcttaggata
     9001 taaaagacca agtatcacac agtctagtgt tcaaaactag acctagctat gggactctgt
     9061 ttctttaaaa ggcttgattc ttacagctcc tctgcaaaaa actgtgtggc tttgacagct
     9121 cttttccagc cttgatataa cttttctcgg cgagactcac tcatgcttgc tttaaacagc
     9181 tgacctgtag catttaattg ctttagcgtc tccatgtcct tccagtagcc tacagcaagc
     9241 ccggctaaaa aggctgctcc tagagctgtg gtttcaagat tttcagcacg agcaatatca
     9301 atccctaaaa tatctgcctg aaactgcatg agcatgttat tcatagccgc tccgccatca
     9361 acacgtaatt gctggatagt gatccctgag tccacctgca tggtatcaat cacatctctg
     9421 acctgataag caatagactg tagggtagcc ttaacaaaat cctcttttgt tgttccacgc
     9481 gttaagccaa atactgagcc gcgtgcattg gaatcccaat aaggagcgcc aagacctgta
     9541 aaggctggta caacatatac ctcatcagca ttggttgaag ccaaggctag ctgttcagac
     9601 tcaaaagagg tttttatcat tcgcaagcca tctcgtagcc attgcacagc agagccagca
     9661 ataaagatag acccttctaa ggcataataa accttgccat taataccata tccaatcgtt
     9721 gttagcaggt tgctgctgga taattgagcc tcttgaccag tattcatgat gataaaagag
     9781 cctgtgccat aggtattttt taccatacca ggctcaaagg ccagttgccc aaatagggct
     9841 gcctgctgat cacctgccat gccagcaata gctacctctc ctccgtaaaa atgaaaagaa
     9901 gccgttttac cataaatttc cgaattagac ctgacctcag gaagcatggc cttagggata
     9961 ttcagcaagg ccaatatctc atcgtcccat tttagctctt tgatattgta tagcatggta
    10021 cgtgctgcat tagaataatc cgtcacatgt accgccccgt ccgttagctt ccaaaccagc
    10081 caggtgtcaa tcgtgccaaa taataattct cccctttcag ctcgctcttg agcccccgga
    10141 acatgatcaa gaagccatct gagcttggtc gcagaaaaat aagcatctat aaccaggcct
    10201 gttttttcat ggatcatttt ggtatagcca tcacgcttta gctgctctgc aatggaggct
    10261 gtttgtctag attgccacac aatagcatta tagatgggca gacctgtctg tttgtcccag
    10321 actaccgttg tttcacgctg gttggtaatg cctatagctt ctatttgctc tggctttata
    10381 ccagactcga taaaggcgtc tgcaataaca gactgcacca aattccaaat gtgattggcg
    10441 ttgtgctcaa cccagccagc ctgtggaaaa agctgtggaa attccttttg actactaacc
    10501 agcgcttctc ctttcttatt gaaaataatg gcacgagagc tcgttgtgcc ctgatcaata
    10561 gccataatat aggtttcagt tcccatgtgt cctccattct atcgctgctg agataggctc
    10621 tctcaatcat agcaagcgct ttctactcta ttatacaaca tttacagccc atagcctatc
    10681 cttctagtca taaaagtatc actctgccaa atcctaagct gataatgcct atcatttcaa
    10741 ctaaacagcc cttatcacag ccaaatacca gcaacaaagg cgggctatag gctagcgcct
    10801 aaatggctgc caacaagctc cagctctatc aggcacaaca aggaacaaca aaaaacctaa
    10861 gcccttttag catataaagg cttaggaatg ttacaggctt ttatcacata agcggtgata
    10921 gctttttaat cgtaaacagg ctcagaggac ttttctaaaa tatctccact attagcatca
    10981 atagtatagc tgtactcctg atccttggcg tcaaactcaa tatcgtagac caccctaccg
    11041 tcgtctgttt ctttcgtcag ctttagcctt tgggcgtcag ctgctgtgat tgaggcgtcc
    11101 ttaaaagcaa gctccttggc cttgtcctct gaaatgccag ctgcttgatc agcctgacca
    11161 ccagctgctt gagctgaagc aggagcctca gtgattggct cagaggattt ttctaggatc
    11221 tcaccggtat tagcgtcaat ggtatagcta tactcctgat ccttagcatc aaactcaata
    11281 tcatagacca ctctaccatc gtctgtttct ttcgtcagct tgagcctttg agcgtcagct
    11341 gctgtgattg aggcgtcctt aaaggcaagt tccttggcct tgtcctctga aacacttgcc
    11401 ttcctatgat tctgagcact gccattttga cctagagcct gattctgttg acgacaagct
    11461 gataggctga ttaaggatag actcgtaaga gctattactg aaagtttttt gattatcatt
    11521 gtattgacct tccgtcttta ttcatcttat ttcctctagt atacattaaa taatctgatt
    11581 ttacaatttt aaagcgctaa aactctctta accaggctta ctcccttata tgataacccc
    11641 caaagagccc ataaggtaaa ggtaaggact ttgctatccc tcaaccaaga atagatcacc
    11701 cagccgaata aaaaaagcaa ttattggtag aatgagaaga attattttgg tcttatttat
    11761 tgccttcacc agctatcaat cactatttaa tgaccatttt ggtatgaacc ctcactgcca
    11821 ctcactatct gacaccaagc tacttttaag taccagcatc gatgtttctt acacctccag
    11881 tgcgtatcca tagccgacct tcagcattta ccagcatttc tgattgatta caaatactcc
    11941 ctaaactgtt gaaaaagtat ctaaacgaac catacaaaac ttaatttacc ttttttctat
    12001 ataaatagct aaaaaacata gtaaggtcac aagggatata agatttacat tgcttatagt
    12061 agtcgataag aaataaaaaa ttaaaaaaat aaagtaagaa gccccttctt tgcccctctt
    12121 agcactgtca accagtatat agataaaaat taaagcataa agacctgaaa aagtaatcaa
    12181 taacatctaa tttaccttat atgccaagca tgctcctaaa gcagtaaagc cgtctataca
    12241 tactcctttt agcaccggat gaggtatttt gcaaaatgta attcctgtct tgagacctcc
    12301 taatcccccg ataacagcat tacctgctgc atttcctcct gaaatatctt gcatttcact
    12361 tattgctaat gctctataat gttccatttc tattatcctc ctaaaacaag gttccaaact
    12421 cagaatcttt ctgtttttct catttctaaa agcctcctgt gacaccaata gatccacaag
    12481 ctactccaca tactggaaat ccaagtgctg cgcctgcact tcctgctcca atcacacctg
    12541 acacattggc agcccaatta ttttttcctc cttcaaagct agcaagcatt tctgtagcca
    12601 ttacgtcaaa ttattgtatt gattgcaaat actccctaaa aatcgatgtt gtccagttgc
    12661 aaccttgaca tatttagtat aacgcttttt ttgtaaaaca ttcctccata tcctaaacag
    12721 tcgttgaaac gtcctaaatg ggagcatttt tttcgtttaa gactgcaaag tgaccattaa
    12781 gggaaggcgt gaagcgacaa gcctgtggct ttaggaacct taaaaacatt aaaagcaagc
    12841 ttctcattgc tattaacaac acaaaaaaag caccagtctg gtcctcacta ggtactagtt
    12901 atcagtcacc cccctaaagt tgacaagaag ccaaaaaaag agaactgact agctctctta
    12961 gtgtgcagac aaatctatct gcttacatta atgacaattc tcagaagtgc aaaagacagc
    13021 tattagccct tacttgagta cctctccttt gcttggccta ctagagattc tctcaatcag
    13081 gcgactagtc cggattaaaa gccagtctag ccaagcccat gaaattgctg atagagctct
    13141 tggcgattca ccttatagtc tttggcgatt gtcttgatcg cctgattagg cttcatgcca
    13201 gcagcaatag cctgttgaac aagtgctagc agatccaaat cctcagcagg ctctgatgcg
    13261 tcagcttgat tggcacctgc cacaatcaat agacactcac ccttgagtgg atggtctgct
    13321 agataggtca agacctctga aatctgacca cgctggtatt cctcaaaaag cttggttaac
    13381 tctctcacca gcaccacctg gcgatcccca tagcaggcca gcaggtttgt tagcgtatcc
    13441 ttaacacgat aaggagattc ataaaagatt tgagtctctg gataatctgc cttagtcatc
    13501 aaaaatgccc tttgctgccc agcttttctt ggcaaaaagc cataaaacag atggggctgg
    13561 ggcgccaagc cactagcaat gaggccggta atgcccgcag aagcacccgg caaagcaaca
    13621 acagtaatat ctcgatcaat agctgctctg actagctcat gaccaggatc tgaaatagag
    13681 ggcataccag catcggagac ctgagccaat gaccttccag ccaacaacag gtccagcaaa
    13741 tctggaattt tatcataagc attatgctca tgaaagctta cctgctttgt ctttatccca
    13801 aaatgcttga gcaacagacc agtatttctc gtatcctctg cacagataat atccacctct
    13861 tttagaacat tgaccgctct aaaggtcata tcctctaggt taccaatagg ggtaggcacc
    13921 agatagagaa cccctgactc tttttcttcc ttgaagctct tttggatttg catgactcta
    13981 ctttctatct aatagctctc gacaaaacat acactcttca tcattttcac gacgttgccc
    14041 atagaaaaaa ttgcagatat gaaagccctc atcataaatg ccctccaagt ggtccttgcc
    14101 ctgcttagaa gaggtcttgg ccagattttc gtgctccaat tgactcaagc gctcacgtaa
    14161 tttggtgttt tcaagcctaa ggatagtatt ttcctctacg agtccttgga cctgcttttt
    14221 cattgcttca atttcagcta aagtcaccat caggttttgt gaaaagccat caaaagcgtc
    14281 aaacagttct tttttattca ctaactttaa cctcctctaa agcataggtt accaaggcca
    14341 gctggtcctt aaagcgaacc tgaatggtat ctgtaaaaag atcaattcct gcaacctcac
    14401 ctggtccctg cgctgttctt actatagtac cataatcagg aaattttttc ttactttctt
    14461 gataaaaatc gtcctcatat tgtaggcagc acagcaagcg accgcagcag cccaaagact
    14521 ttgccgaatg caaggacagc ccttgatgtt ttagcatttt gattgagact ggaggaaact
    14581 ctcctaaaaa gcttgaacag catagtgggc gaccacaggg acccagccct ccataaaccc
    14641 ttgcctcctc acgactatta atctgacgca gctcaatcct tgtcttgaaa taggcagcca
    14701 aatccttgag gagctggcga aaatcaacac gctcctgagc ggtaaaggta atcaaaacat
    14761 aacgtctctc aagggagaaa acaatgtcaa ccaaggtcat gtctaagcca tttctgtcaa
    14821 tcatctctgc tactttttgc tttgactggg ctgctagctg aaggttttgc tggtaagcct
    14881 tgtagtccat gtcattggca ggtctcaaaa cagagggcat atcctttggc aggtcgtcct
    14941 tacaaaagct ttttatcgga gaattgacca ctgccaatcg actgcccttg ccatcagata
    15001 tgacaagctt ggtttgcaca ggaaaggcct gatcggtttg aacgtacctg acagagcagg
    15061 tgtcacaata tttaattcca atcgtactta tcatgaaatc accatatatt ctaacgtatt
    15121 ttgaaagctg acattgcttt gccacataag tctagcctga taaacagcct ccagataggt
    15181 aaaagcattt tgtcgactgt agtccttcgc caagattaag gttaaaagag ttagtgccat
    15241 gtcctgctcc tctttttcct ctgctagctg aaccaagcga ttaagctcca gataagcctg
    15301 ttccttatcc tgaaaccaga tggaaacaaa acgctcagcc tgcgccatca gctccaacag
    15361 cctggtgttt tcagaaaaag cggtaagctg ctgggcattg gctgctaatc tggctaagag
    15421 gtctgcttga tgtttcaaaa gccccttttt ttgggccagc tcagagaggt agtgctcatc
    15481 ttttggaaag tgaaaaacct gtgtacggct cttgatcgtt ggtaggacct gattgtcatc
    15541 attcgttagt aaaaacatat agcaatcccc ttgtggctct tctatatatt ttaaaatgct
    15601 gttagctgca ttgacatgca tcttatcaca atccttaatg ataaaaacct gccgcctgcc
    15661 ctcatagccg gtctgcgaaa aatttgtcat catttctttg acggtatcag tcttgataag
    15721 ctgaccgaca ggctctaaga tggtgacatc tgaaaagtca ttgtgctcaa tcagctggca
    15781 agcacgacag tgatgacaag gagcattgcc tcttttttgt tcgcaaaaaa gagtcttggc
    15841 taaaaaaaga gccatgtcaa aattggcaaa atcacctgaa aagaggtagg catgatttag
    15901 acgttttttt tgcaaaatct cttgaaaggc ctgatagacc ctaggagcct tttgagccaa
    15961 atccattcct aacctcctgc tatgcttgac tgtgtgtgat aatggcagct aaagccgctg
    16021 acacaacgct ttctaagtcc tgtgatgcat caatcttgac aatacgctgg ggattttcca
    16081 aagccagctc cagatagccc ttacgaacac gctggtgcaa atctaattgc tcaagatcaa
    16141 gacgattgat ctctcgctca gtattttgtg caatccttgc caatccaagc tctgagggca
    16201 catcaaaata cagggttaaa tcagggtcaa caccatctgt tgcaaaatga ttgagccatt
    16261 gaatggcttg cttatccagc cctcttccgg cgccttgata agcaactgaa ctgtcaataa
    16321 aacgatccac caaaaccaag tgtcctgact caagagctgg catgatcttt tcaaccaaat
    16381 gctgccttct tgctgcaata tagagcagca gctctgtttt atcgtccatg gtcgtgtgac
    16441 tgacatctaa gatcagctga cgaatcttct cagcaatcgc aacgcctcca ggctctctcg
    16501 ttgttacaat ggtttgtcct agagctgcct gtaagagtgg caccagtctt tccagcaccg
    16561 ttgtttttcc tgctccgtct ggaccttcaa acgttattaa ttttcctcta gtcatcttta
    16621 ttcctttgtt tatcgttacc tctattttac caaaatttgc ctgaaaaagc actgccaatt
    16681 cattgggcag tgccagatca gaaaaaagcc tttttgtgct gccttttagg cgataggaat
    16741 aaaaagccag ccctcaaagc agcagcctaa gacttgtgcc tcacacctca aagcctatga
    16801 gcagccactc gataaatgac aatcgtctca gctcttattt tctttgccta agcaagccag
    16861 cagggctgat ccatcagctt tgagcaattg atgagctaag acatgctata taagacagga
    16921 tcaggcctac ttagccctgc tcaggtaggg cttgaggctc tagaggctca cgatgtaaat
    16981 tcccaacaaa atcacaatca atgtcatcaa aggctgatac cttcacctct ttgacaaatg
    17041 ttagccgact aatgtccttt agcttttctt ccatgtcctc tttattgatg taaataacaa
    17101 ggtatcgaga acgcctggaa tggtagtaca agtcaccata tttcatcact tttctagcgt
    17161 ctcgattgta atacaggtag ataaccagcc caattctctg ctgtttttga aacatttagg
    17221 tactcttttc ttttatattt tgatacggtc caagctcatg tcgaggtcta tttgtcgcca
    17281 agggaagtcc tgtgtcgaca agaatatcct cagacactgc ttctgcaata gctgtcgaaa
    17341 tcgtcgccaa aacctcctgc aaatcaacct gtgccaagcg cagatcagca accaatggat
    17401 gcaggtcaag ctggcgcttt tgatgaagta attggcagcg caacgctcta gcatctggac
    17461 acaacttaag caagtcctgc ctaagctcat aatcctgctt aagctcctca aataaggcta
    17521 actcggtctg tagggccaaa tctgcctcaa aagccttttt agccaaggca taggcctgat
    17581 actggctgct tgtcctaata tcctgaacca gctgctcaat agccttttca atggcaaaca
    17641 attcttcatt tatgattagc ataggttaat tataccataa ttttaaggaa gatagccctc
    17701 tttagcatgc aaaaagcccc tgaaacaatt tgtttcagaa gctgttaagc tattttacta
    17761 agctctctaa gctagctcat tattttccat gatttcatca ataaagccat aggctagggt
    17821 ttcttctgcg ctcatccaat aatcacgctc agcgtcctta tggatttgtt tgatcgtttt
    17881 accggcattt tgtgccaaaa tcttttccag gcggtgacgt gtctttaata aatgctcagc
    17941 agcaatggcc atatccgtct gctgcgtacc acctcctgtg cctcccatag gctggtgaat
    18001 catatattct gcatttggaa gcataaagcg cttgcccttt gcacctgatg aagcaataac
    18061 ggttcccata gaagcagcca tacccataac aatggtttgc acatctgcct taataaagtt
    18121 catcgtatca acaatagcta aaccagctga tacagagcct cctggggtat tcacatagag
    18181 gtaaatatct tttgtgttgt cttgggcatc taaaaacaag agctgcgcaa taacagagtt
    18241 tgccatatta tcctctactg gaccagtcag catgataata cggtccttta acagacgtga
    18301 ataaatgtca taagaacgct ctccacgact ggtttgttca ataactacag gaatcataaa
    18361 aatctccaat ctatcgtgac tgtctaacac cactctgcct catgcagtga caggcagtca
    18421 aacacatctt tttataatga ttgaccttat tataatctct tggtcaaaaa aggtcaaatg
    18481 ataaacttgc ttttaaaaac cttccagcct aaactagaaa gtcttattag ctttagcagg
    18541 ctagcctcta gcaagcagag cctagcacaa ccaaagcctg tagcctttta cttggtacca
    18601 aataagcgat caccagcatc tccaagacca ggaacaatgt agccatgatc atttaatctt
    18661 tcatcaaggg ctgcggtata aatgtcaaca tctgggtgag cctcctgaag ctttttaacc
    18721 ccttctggtg ctgctaccag acacacaaac ttaatattag cagccccacg ctttttcagt
    18781 gaatccactg caagaatagc agagccgcca gtagccagca tcggatcaac aataaaaatt
    18841 tggcgctgat caatatcctc tggcagcttc accaaatatt caaccggctc caaggtctcc
    18901 tcgttacgat acataccgat gtgaccaacc ttggcagctg gcacaagact aagaaagcca
    18961 tccaccatac caataccagc tctaagaatc ggaacaattg ctaatttttt acctgctaac
    19021 tgcttttgaa ccgtcttggc aaccggtgtt tgaatctcaa catcctctaa tggcaagtca
    19081 cgagaaacct cgtagcccat aagcattgca atttcattga ccagctctct aaaatccttg
    19141 gttgaggtat cctgacgacg caggattgat agcttatgct gaataagtgg atgcgaaata
    19201 acctgacatt ttcccatgat gacgtacttc cttctttatt ttttacactt ttgctattat
    19261 accaaaaaat tgaaaacctt gcttactttt ttcagatccg gttgaaatga taaaagcaag
    19321 aatctgatca gctagctgcc tgcttcagct gccttgatct tgggtgtcaa agtcccaatt
    19381 tttggcgata cctagctgct ctgctgccaa ttaatttgtc cagctgacgc gtcaataacg
    19441 tcatgtaggc gtaaacaccc attcccaagc caccaataat cactaagtaa agcaggctag
    19501 tcaatctgcc tgtcggctta aacaaatagc ccaaaaacca gttagctagt agcacaatca
    19561 ggcccatcaa tgctgtctca atcaccgtta gtaatatacg cttatgcagc agcttacggt
    19621 taaatcgtgt gacctgatgt agacgacggt acatgagata gataggcact agcaagccaa
    19681 gggtcgtagc taacaaagga ccataagcat gaaacagata gatcaaagga acctgcaaaa
    19741 ccagcttgac aaaaacacca taagcaaaat aatagatggc cttacggttt tcaaacaggg
    19801 cctgcagcat cggagaaaaa agcgtataca aggccatcaa tagggtaagg caaagcacag
    19861 caacaaacag cctaacagcc tgtccctcgc tactaccgta aaaaaccgta taaagaggcc
    19921 ttgccagtat aatagctcct gtcagagcag gcaataaaaa catcagcagc atttcaatgt
    19981 tgttaatgat caggcgcgct gctgctcgca tgtccttttt aatgtaattt tctgtcaata
    20041 aggcaatacc aacactacca attgaagcgg ctactgcaat gagcaccatg gtgattttag
    20101 cagggttggc gttaaaatac ccaaacagca cccagagctg agaacgcgtg tagctggtaa
    20161 acagagtcat cgtattgaca aaggtccact gatcaaggag ctgaaaggcc tgaatcgcac
    20221 ttcctgtaat aataaaggga atcgactcct ttaacgtttc aataagcaag cccttgatgt
    20281 caataggaat cgcatgctct gtcttggtaa aaatagcctt taaaaggccc tgcgtccaga
    20341 aataataaaa gagcaccgcc atactggcta tcattccaat aaaagcagca aaggtggact
    20401 gcgtaacagc tgcaatatag tccttagacc ccattttcat gatgaaaaag gttgttagaa
    20461 gcatccagat cacacgaacc agctgctcag caatttggct aagagcatag ggcttaatct
    20521 ccttatagcc ctgaaaaatc cccctaatca cgctcatcac tggaaaaaca aaaacagcta
    20581 atgataagct atgcataatc gggacaaggg tctcatcacc accggacaag cgagcaaaga
    20641 gcggagatcc cagatacatc agcactgaga aaatcaagcc taataccagc ataaccttta
    20701 gagtgcttcg aatgagctga tagctatgct cttgctgtcc catcgagttg tacttagcga
    20761 cctgcttagc aatggcaaca tttagccctg ttgtcgaaat caacaaaaaa taggcataca
    20821 cattgtatcc catattaaag agcgcatttg cctgtatcgc atactgcccc atccatatgt
    20881 accatggaat aatatataga acgcctaaaa gtcggctaat aaaattacct gcggtggacc
    20941 aggctgctcc ctgaaccatc agctgttctt gtgtcaattg ttttttttct gtcgacatat
    21001 ccgttcttcc tagtttttat agctttatta taaacttttg cttgtgactt gtaaaacaag
    21061 aacattaagg ataaaataag gctatgataa caattgagca cttattaacc attttaaaaa
    21121 aggaccataa tttccgagag gttcttgatc aagacggcta ccactttaac tatagcggtc
    21181 tacagtttga cagccttagc tacgacagca gacaagcaga tgagcagacg ctcttttttg
    21241 ctaagggatc agcttttaag gctgactttt tgagacaggc cattgccaag ggactaagac
    21301 tctatgtttc agagattgac tatcaggtag ggatccctgt tattcttgtt aacaatatta
    21361 agcacgctat gagcctagct gcgatggcct tttatgatta cccacaaaat aagctcaagc
    21421 tattagcctt caccggaaca aagggcaaga caactgctgc ctactttgcc tatcatatgc
    21481 taaaggaatc tcataagcct gccctgctct ctacaatgaa cacgacctta gatggccaac
    21541 acttttttaa atcgcagtta accacacctg aaagtcttga tttatttgcg atgatggctc
    21601 agtgtgtggc taatggcatg acgcatttgg tgatggaggt ctctagtcaa gcctacttgg
    21661 tcgggcgtat ctacggctta acctttgatg tcggtgtctt tcttaatatt agccccgatc
    21721 acatcggacc aatcgagcac ccaagctttg aggattattt ttaccataag cggctcttaa
    21781 tggaaaatag ccgagctgtt gtggtcaata gcggtatgga gcattttaat atcctagcag
    21841 agcaggtggc tgataagcct catgattttt atggcaaagg ggcttgcaat aggctgctgc
    21901 agcggcaggc cttctcattt caagcagccg gcaaggtagc tggagactat gcgattcaat
    21961 taattggcag cttcaatcaa gaaaatgcta tggctgctgg actagcctgt cttcgactgg
    22021 gggcaagcct agaggatatc cgccaaggca ttgctaagac aaacgtccct ggccgcatgg
    22081 aggtcttaac catgaccaat caggccaagg tatttgttga ttatgcacat aacggtgata
    22141 gccttgaaaa gctcctatct gttgtcgaag agtaccagaa aggccagatt tacttgattc
    22201 taggagcacc gggcaataaa ggcgagagcc gtcgggctga ttttgggcaa gtcatcaacc
    22261 agcaccccaa tgttcgtatt attctgactg ctgatgatcc taattttgag gacccacagc
    22321 tgatttcaga ggagattgct agctatattc accgcgaggt tgatattatc attgaccgta
    22381 aagaagcaat caagactggt atggagcgct gtcagaatga gcaggatgca ctcattattg
    22441 ctggcaaggg ggctgatgct tatcagattg tcaagggaca aaagactgcc tatgcaggtg
    22501 atttagcgat tgcaaagagc tacctataga ctggtctaac aggctaaaca gtaataattc
    22561 ttaagattac tgataatgat tctaagctgg ctcctttttt agcataaact cagtaattag
    22621 attctgaaag gcttttttag gccttttttc tatgctataa tgggatagct tttaagagaa
    22681 agcgcactat tatagtcaga ccaaaaaagc gactagcatt tcataggcta tcagcccctt
    22741 agaattttgc tagctggctt tgcttgacta ttagaaagga gaaaaaccat gtcaacaatc
    22801 agtgctgaga ggatttcagc tggctatgat caatcgctta tcatcagcaa cttatctgtc
    22861 actattcccg aaggaaaggt aacaaccatc atcggtgcta atggctgtgg gaagtcaacc
    22921 cttttaaaga ctctggcacg actattgcca ctcaaagcag ggcaggttct cttagatgga
    22981 caagccattg ctagactagc aaccaaggac gttgccagaa cactagcagt tttacctcag
    23041 ctgcaagaag ctactacagc tactgtctat gagctggttt cttatgggcg ttatccccac
    23101 caatcctacc taggacaact cagtcaagct gataaggata agatttgctg ggcaatggag
    23161 gtcacaagca tggcacccta tgctcatcag gctgttgatg ccctgtcagg cggccaacgt
    23221 caaagggcct ggattgctat ggccttagca caggatactg atattatttt tctagatgag
    23281 ccaacaacct acttagatat gaatcatcag ctcgatattt tagaattact aaaggagctc
    23341 aatcaggtct ctggaaaaac aatcgtgatg gtccttcatg atttaaatct ttcagcacgc
    23401 tactcggatc atctgatcgc catgaaaaat ggacatatca aatattctgg agaggtcaac
    23461 caggtgatga cgccagagat gattcaagac atttttcaag taaaggctca gctcgtcact
    23521 gatcctctct atcattgccc tacattgctg acctatcagc tgatataaat ttattctagg
    23581 agaatagaat acatgaaaaa actactgctt attttaactg tttttgtgac agcttttaca
    23641 ttagtcgcct gctcaagtca aagcaagcaa caagaaagca ccagcaaagc aagcctatcc
    23701 cacaagccaa aaattgctgg agtgacctat tatggtgaca ttcctgtcaa gccaaagcgc
    23761 gtggttagct tagcagctac atatactggt tacttggcaa aattagacct tcatctggtc
    23821 ggtgtcacct cctacgacaa aaagaaccct gttttaacaa aaagcattac tcaagccaag
    23881 caggtggcag ctactgacct agaggctatt acagcactag agcctgatct cattgttgtt
    23941 ggctcaacag aagaaaacat tgaccagcta gcaaaaatcg caccactaat ctccattgaa
    24001 taccgcaagc gtgattattt gcaggtgttt tctgattttg gccgtatttt taacaaggaa
    24061 aaggaaactg accaatggtt ggccgactgg aaacaaaaaa caagtgacta tgaaaaagaa
    24121 ataaaacaag tcaccggatc agctgctacc tttacaatca tggggctcta tgaaaaggaa
    24181 atttaccttt ttggtaagga ctggggaaga ggtggtgaaa ttattcatca ggccttacat
    24241 tatgatgctc ccgaaaaggt gaaaaaagag gtgtttaagc agggctatct gtccttatca
    24301 caggaggttc taccagatta tattggtgat tatgtgattg ttgctgctga ggatgaccaa
    24361 accggctcag ccttatatga gagcgacctt tggcagcaga tccctgctgt gaccaacaat
    24421 catgtcatca aggtcaacgc taatgtcttt tacttcacag acccactgtc actggagcac
    24481 cagcttgagg ttctaaaaaa ggctatcctc tcaactggtg caagtcaata aaaacttaag
    24541 atgacagctc aacatcatac taagcctaaa ctagctaaag cagctcctcc ttggctgatc
    24601 ttaaccttta tcagcttaac tctagtgctt gccatttact gcagtctgag gtttggggct
    24661 gtgtcactat cacatcagga gctctatcat attctacttg gaaagcagga ccagggtcaa
    24721 aaggccagca ttattttgga cattcgcctg ccccgcttga ttttagcagc tctagttggt
    24781 gctgcacttg ctgtttcagg agctatcatg caaggcatta ccagaaatcc cattgccgag
    24841 cctggcttac tgggaatcaa ctctggagct gggctggcat tagtcatcgg ctatgctttt
    24901 tcccctcatc ttcattattc gacaattata ttactttcct tgctagggtc actcttagcg
    24961 accctattaa ttctcagcct agcctatcaa gctggtaagg gctacactca aatgaggctt
    25021 attttagcag gagcgatgat atctatgcta ctgtcagcta tcggacaagg aataacaact
    25081 tattgtcacc tagccaatgc cattattggc tggcaggcgg gaggattgat cggggtcaat
    25141 tggcagatgg ttagctatgt tgcgccactc atcatctgtg gcttagccct atcttatctg
    25201 ctagcctatc atttgaccat tttaagctta agtcaagagc aggccaaggc cctagggcaa
    25261 cgcaccttct tgattagcct tatctttatt ggacttgtgc tgcttctgtc ttctgctgct
    25321 gtagcagtag ccggcagcat ttcctttgtc ggcttgatta tccctcatgc catcacatta
    25381 gtcactgcta aggattaccg ctggatcctg ccgctagcta ctcttcttgg agccagcttt
    25441 atgctttggg tagactttgc ctgtcggaat atcaatcccc cctatgaaac accgctatct
    25501 gctttgatca gctttattgg gctgccctgc tttttatggc tagttagaaa aggaggtcgc
    25561 ttttgacagc tactaaaaga cacgtcccat tatttctagg actaatctct ggactggtct
    25621 gtttgatgat tatttccttg tctattgggg aatctagcat gtcaccattg gaggtcgtca
    25681 gggtgctttt tggtaaatcc actgctgata tggccttgat catcaccaac attagactcc
    25741 caagaatttt agctgcctgt atcggtggcg gctcactggc cctttctggc ttaatgctgc
    25801 aaagcttaac gcgaaatcat ctggcagatt ctggcatact aggcattaat gctggtgctg
    25861 gtatggctat tacccttgtc atatcctaca gcactagtaa cagtctgacc agcaggcaag
    25921 ggctgccgct tatgaccata tccggggcaa tggcaaccat tgtcttggtc tacctgctct
    25981 cacttcgtca tggccatatt gatcctattc ggctgattgt cactggcgta gggctatcaa
    26041 ccatgctatc tagcctgatg attgcctttg tcggcaatgt gaaccgttat aaggtggatt
    26101 atgtgattca ttggctaagc gggcagctaa caggcgatga ttggtccaag ctaagcattg
    26161 ttgctccctt attggggatc acttggctgc tagcctttag tcaagcctat aagctcaaca
    26221 tcatggcatt aaatgatgaa gcaagcatgg ctctaggctt caagctccat cagtaccgta
    26281 ccattgttct tgcactatct gcgattctct cagccctaag tgttattttg gtcggaaaca
    26341 tcacctttat tggtctgata gcaggccata ccagcaaacg actagtggga gctgatcacc
    26401 gattaagcct gcctgtcagc cttttcatcg gcatgattct gcttctcttg gctgacacta
    26461 tcggacgagt ctatctcgtc ggcagcaata taccaaccgg tattcttgtc tcaattattg
    26521 gtgcatccta ttttctctat ctgatggtca aaatgacata agagcctctg ctgcatagct
    26581 taaagggctc agcaagcata aatggcttag actcaactgt tttacagtgt gggtctaagc
    26641 cattttttat tcatcaagtc aactcttaat cagcgtagaa aatcagctgc tccttatcaa
    26701 aagccagctt caggcagtat ttagtggcct ctactttttc aatatagcct agaagctcca
    26761 aggcattcac aaaaatatct gtccgctttt gcataacaat ctcttttcta gcaaatttta
    26821 gaagaaagct ggtcatgtac ttcaaggcat agtcctgatt cacatcacct aatagggcat
    26881 agagccttaa ttgctcatca gatagggctt cccctcttct taagcggtaa aaataattgg
    26941 caagcgtcag cttatctcgg tcaatggttg ttttttcctt gatcaaaacc tgattggtct
    27001 gattagacag cactgtctca aacaccaagg ccatcaaagc ttcatataga tctgatgccc
    27061 tatccacaaa gattagatct tctaatgtca cctgctgcag gtcatctagc aagggcagac
    27121 acagatagta gcgtctgttt tttcgacaga tatagccagc ctgaatgtaa gcttcaagcg
    27181 ccttatcaat ccccttaaca tgagaaaagg cctgcttaat gtgacgcagg gttacgtcat
    27241 catgctgatt gaggtaatga ataaggtctt gaaaaaaagg ctgacgcgtt aatttatcag
    27301 ggttaaaaat ggtaatcata ctactattat agcaaaaaga ccaaagggct gctgataaaa
    27361 atcaacaccc ctctacaggc aagctctatg ctccaaagct ttcagttaat tgagggacaa
    27421 cctgcttttt acgagataca gcacctgcta ggaaagcatg attatcctca agcttaaagc
    27481 taaaggctgc ctcaacctta tccatattcg caccaagcgc caaaatctct gaatttgaat
    27541 taacaatatc tgtaatcatc aagacaaaat cagaatagcc ctcacttgcc atcacctctc
    27601 taatagcggc ctcaatagcc tccttgcgct ctaacacctc tgcaatgtca acggtattga
    27661 cctgggctac acgaactgcg ttgccattta attcaaaggt cttagcatca atatcaatca
    27721 attctgcttc tgatttactt gcaaggtttg ttccggcctt tagcatagcc ataccgtatt
    27781 cctctagctt aactcctgct aactctgcta attccgcagc aacacgatga tctgaagcat
    27841 gcgttgttgg tgattttaac agcaaggtat cagaaatcaa gccagacaaa agcatgcctg
    27901 caatgtcctt tggcacatca accctatttt ccttgaacag gcggtaaaca atagatgagg
    27961 cagagccaac aggttcgaca cgcatataaa gcggatttgc tgtctcaaaa ttagccaccc
    28021 gatggtggtc aacaatacca tacacctcaa cctcacgaat atccgaaata gactgtggaa
    28081 attcgttatg gtctgttaga ataacatgac tagcaccctc tgcttttgct gatgtcacca
    28141 ctcttggtgc tgatacccca aaatagtcaa gggcaaaggc tgtttcttca tttgggtcac
    28201 ccagagcgac tacctccgta tccaaatcaa aggctttttt tgctaagtag tcaaaagcat
    28261 acgatgatgc gatggcatca gtatctggat tttgatgacc aaaaactaat agttttgaca
    28321 taaagtttct acctcattct ctttattcat cttattgtag cagaaatagg ctctaaaatc
    28381 aaagaagatt ccccagtcac aggccaagag tctaaagggc ataagggcac agaatctcag
    28441 gtattaaaga gtcctgtcaa acacacaaga acaggcaagc cagtccaaaa agcaatgcct
    28501 tctataatga gctattcagc tatttgggga caatacactg tccttgattg gtttaatgct
    28561 tcaaggatta ctttttggca cgtgtctgag ctcgcttaaa aacactgaag gtctcatcaa
    28621 gccagccgct tcatcagcaa aaaaacggct ctataatttc catggtggat ttacccacta
    28681 cagaaattat agagcccatt tacctcgctt tgcacatcac acaagagaaa acgagcttcg
    28741 tctcgtgctt agttatcagt cacccactac agttgacatg gggccaaaaa aagctgggca
    28801 tttcccaact ctagcttagc ctatgattga tgaatacggt tcatgtattc agtataggat
    28861 tctgtatgca gcagcttttt ggcattctcc acccgctcct tggttggtgg cttaacgccc
    28921 tcaagctggt atggaatccc taactcgcgc catttgaact ctcccatcgt atgataaggg
    28981 agtacctcaa acttgtcgac atttctcaag gtcttgacaa acgcatctaa gcgtaccaag
    29041 tgatcatcaa tgtctgtcaa gccaggcacc aagacatggc gaatccagac gggcacctgc
    29101 ctatcagaga ggtagcgagc aaactgcagg atatttttat tgggctgacg ggtgacaagc
    29161 ttatgctgct cctcgtcaat ctcctttaag tccagcaaaa tcaaatcagt aactgctaat
    29221 aatgtttcta acagctcatg gtattcaggg gttggacgat aggcaaagcc acaggtatct
    29281 agcgttgtat ggatacctag ctttttggcc tcagtaaaga gcgcagtgat aaagtccatt
    29341 tgcagcatag cctcaccacc tgacacagtg attccaccct ttttccccca aaagtgccta
    29401 tattgcagag cctcctttag gacatcatta acggttcggc gttgagattg attggtttcc
    29461 atagcccagg tgtccggatt atggcaatac tggcaacgca tcttgcagcc ctgcaaaaaa
    29521 atgataaaac gtatccccgg accatcaaca gaaccaaagc tttctgtaga atgcaccatt
    29581 ccagttactt gcccataatc tacttcaacc attgtgtctc cttcaccctt gtaaatggtt
    29641 ttacgttttc attatatcat gtttcatcaa aaagactaag ctcaatgcct agtcttcagt
    29701 aatattctgt tctatattag aaatagtaag tttcaatttg gtgatacgac cgtcctttac
    29761 tttgtcattg accaaaacca gatgcttttg cttgctatca caggcaaagc tctctttctc
    29821 cttttgactt ggaatggtac caatccctgt caaataaaag cccgcgatgg tatcgacatc
    29881 atcactttct aattctgtgt caaaatactc gttaaagtcg ttgagcgtca ttgtccctgt
    29941 gacaatatag gtgttgtcat caatgtgatg aacaaattgc tcagccttgt ctgtctcatc
    30001 atcaatctca ccaacgattt cctcaagcaa atcctcaagc gtcaccaaac ctgcaacccc
    30061 tccgtactca tcaagtagga tagccatctg gttttgagta tttcgcaatt gcctcaacaa
    30121 atcatctaca aaaatcgttt ctggtacaaa gagcggctcc tgcagaagct ttctcatgct
    30181 gatgttttca aagccctgac gaaagcctga ttctaaaagc cttttggtat gaattaagcc
    30241 gatcaccttg tccttgtcaa catcataaac tggaatacga gagaagctct gctttaggat
    30301 ttccttgata ttgtctagcg tatcatcgtt aatgtcaatc atgaaggcat ctgtccttgg
    30361 aaccatcacc tcacgcgcca tcatctcatc aagcgagaaa atcccctgca gcatttcaat
    30421 ctcttcggca tcaagcgttg cctcgctgtt agtcagcatg tactcaatct catcacgcgt
    30481 catgcgctca tctgcgtcat caaaggtcat tggggtaatc cggctcagta aatttgtcga
    30541 cgccgataag agccaaacaa agggactaac caatttcccc aagataatga tcactggggc
    30601 agaaatcaca gcaagcttgt cttttagatt catagctatc cgcttggggt ataactctcc
    30661 caaaacaatc gagacatagg tcaagaacac caaagaaata atgctaccag ctgtttgagc
    30721 ggtcgcagaa ccacctaacc agccagaaat aacctgccct aaagaggctg acaggctcgc
    30781 ccctgacaag aggctaataa aggtaatacc aacctgaatg gtcgataaaa agttattggg
    30841 ctgctctaaa acacgcagca agcgatcata cctcttatcc ccatcggcag ccttttgctc
    30901 cacacgagag cgatttaagg ataccagagc catctcactg gctgagaaaa aggcatttaa
    30961 caaggttaga atgactaaca ataaaaactg aatcaataaa ggctgactca cagggtcttc
    31021 cattaatata actcctaaaa cataatatac tacttcatta tatcacaatt gtcgccaaag
    31081 attgctgatt tatttctttt tcctgagaaa tcacagacag tctaagccct gacataaggc
    31141 tggctgaagc ttaatcagta gctgctattt tttccagcat gattaaaaat ggcggctgat
    31201 tcatctgatt gatcggctga tagagcattg ctgttacctg gcgctgattg agctgaccaa
    31261 tatagtccaa aagctcttcc ttctccctac taccgccatc atgaccataa tacaccatga
    31321 tagcaatccg tccacctagc tcaagccgat caagtatttt agctagggct aatatggtcg
    31381 tctcaggcct tgtgatcaac gacttatctg cattgggtag atagcccaga ttaaaaatgg
    31441 ctgcccgaat gggctcctta acatattgat ccacctgctc gtgtccagct aaaataagct
    31501 ctgcattagt caagccttgc tgctccaagc gctcttgtgt cttggtcagt gcctgctgct
    31561 gcacatcaaa agcataaacc ctttgtgaca gacttgctaa aaaggcagtg tcatagccat
    31621 ttcccatagt agcatcaaca gcaatactct gcttatccaa aacttctttt aaaaattcat
    31681 gtgatacatg aataggacgc tttatcatct tatcctccta agcaaatact tcaaatgccg
    31741 cgataccatc tagtatgtct aagtcaatat gccttcggcc gtaacaatct agcacataat
    31801 ctttataccg atctgttttt agattgaatt gaagcgacca gatcagccaa aaaagatcaa
    31861 tatgtcgatc gctttttcct gcctcccccc aatcaatcat ggactgaaat tgccaccgat
    31921 ccaagatcat atttggcaaa caaaaatccc catgaatcag agtttcatgc tgtaacaaga
    31981 gcttaagctc ctgaatccgc ctgtaagcct cctcctggga ctgaaaccgt tgctgaggcg
    32041 gtaaaaagca ctgattgaac cgcccttggt gataaccagc ctcagcagct tcgatatagg
    32101 ctagcgtttt gtcagctaca ggaaaatcag acaaagacag gctatgcagc tttagcatat
    32161 gatcaactaa gatacgacat aagcgcttgg gatcggacaa atattcaata tgactggcgt
    32221 cctctcctgc tacctttgcg gttaaaagcc aatcctgatc accgctgata taatcaagca
    32281 cctctgttgc taagccctta ctatgacaat accgagttag ggcggcctcc ttggcaagcc
    32341 tacctttagc ggctgttttt agaaaatagc cctgcccttt atcaatagca taaacacgtg
    32401 cctctgccga gctactgcta tcataaacca aactgttttg taacagtttt tttaaaacag
    32461 gtggtaggct cagctcctct cctgctatca atctttgttt cattgcttcc cccgattatc
    32521 ccttaagctt acagccctgc cagctatttc ttctttccat ttctaggtca atcgcattca
    32581 aaacctccca tttattcagg ctccacatgg gaccaatcag catgtcccta ggcgcatcac
    32641 ctgtgatgcg atgaataatg atatgctcag gtatgatttc tagctgatca cagataatcg
    32701 atacatagtc cttctgactc aagagctgca agcgtccctc atgatagtct ctttgcatac
    32761 gcgtattggt catcaggtgc agcaaatgca gcttaatgcc ttgaatatca ttgtctgtga
    32821 cacagcgtct aacgttttcg atcatcatct catgggtttc accaggcaag ccattaatca
    32881 agtgagacac aatgttaatg ttagggtact gcctcagacg ctgaaccgtt tccttataca
    32941 agtcataaga atgcgcccga ttaatcagct gggaggtggc ttcataagtt gtttgcagcc
    33001 caagctccac tgtcacatgc atgcgctctg atagctcagc caaataagca atcgtctcat
    33061 ctggcaaaca atcaggcctt gttccgatat tgataccaac aacgccaggc tcattgattg
    33121 cttgctcata gcgctcgcga ataacctcta gcttatcatg cgtattggta aaattttgaa
    33181 aataaaccaa atactgattg acctcaggcc acttgcgatg cataaaatca atttctttgt
    33241 aaaattgttc cctgataggt gcatcaggcg ccacaatcgc atcacctgag ccagaaacgg
    33301 tacaaaaggt gcagccacca tgagcaactg tcccatcacg attaggacag tcaaagccag
    33361 catcaatggg caccttgaaa attttagcac caaataaacg acgataatac tcatttaagg
    33421 tctgatatct ttttgtcatg cctctattgt agcacaaatc ccccgattaa cagcagaaga
    33481 tctcaattgg ctgctacttc tctgattgat gagccaaagc aaggcaacta aaaaggattg
    33541 aagaagacct ctggaagaga cctgccttca atcactagct tttctagaac tgatctgtaa
    33601 cgcgccatac agctgactga tcactggatt tacttttgct ttagctgaaa acgccattca
    33661 aagcgctttt gatcataaaa aggataaagc agctgaagta tgccaaagcc taaggcatag
    33721 ccagccaaca catcgctagg ataatgcact cccagataaa tgcgtgacaa gcctatcagc
    33781 aaaatcaagg ccaaaagggc tatatcaacc agccagcgta aggaggctga ctgcaatctt
    33841 tgatggcaaa taatcagcag acttccaata atcaaaaggc ttcccatcga atggccactc
    33901 ggaaaagaat agccagaagc atgcaccaaa tgctcaatgc tgggtcttgg tctttgatac
    33961 aagagcttta gcacccaaat caaaagggcc gcaaaaacac catttgatag gacaaataag
    34021 gcctcagctc tccagctcaa ggccaataaa gccagcacag caacaacaac aatcactgcc
    34081 tgtgtactaa catttccagc tacagtgatc cctttaaaaa actgggttag cccttcaggc
    34141 agatgacctc ttagggctaa ccgaagctga ctatcaaaag acgttaggtc ttcgggaaaa
    34201 aatttaacaa tatagccaag caccacaaat agtagcatag caaaggaaga caatagcaga
    34261 tgttgttgtt tatgtttcat gatatgaatt cggatatctc tctaaaattg gtttacctgc
    34321 aatatacacg aaataaaaga caattgcaaa tattagcccc tccaaaaggt tgaaaggaat
    34381 gaccattgta aatatgtagc gagcagtacc aataaaagct ttaatatcaa agccagcaaa
    34441 cttggcatat aagggaatag caaagacata gttcatgaca accataccaa gcgttaacag
    34501 ccctgtcccc acaagactag ctagtacata ggtgaccagc cctttctgac gatgccaaat
    34561 caaggcaaag gcagtgataa aaagcgcaac tgctataaca ttcatcggta taccaatcaa
    34621 atcattaacg ccatgattgt ttaaggctag tctaagcaag gtcctcaccg ctaaaatcaa
    34681 gttagcttgc tttagatcca tcaagaccaa gcctaacaaa atcggaatga tactaaaatc
    34741 aatctttaaa aagctggctc ctggaataat ggaaaacccc acaaacatca ggcaaaagga
    34801 tatggctgaa agaatggcaa ccatcaccag ttgatgtgtt tttgacataa aaaattcctc
    34861 caattttgac aaattgaaag aagctccttc gtatgagcag gcaaaaagtc aactcaaaaa
    34921 cccggtcttc tctcttccag actttactgt cggttgtgga atcacaccac atcagcttgc
    34981 gctcgcggac ttctagctgc actagtcacc gccggtcggg aattacaccc tgccctgaag
    35041 acacttatag catagcaaat ttaaacctat agcgcaagac atttttttga agcctagctt
    35101 ttccaacaaa cacaagacat caggcaaaaa agctagatga aagcaacagc aagaaaaatc
    35161 actttgaggc tacaaagctc tctacgaggt aggccaccct gtgacatggc actagcctag
    35221 ctcaaggcaa aaaagagcag actagaagaa acctccaata acctgctctg gtattactac
    35281 cgttgtcccc tttacggtca tagacacacc taaccaatga aaactccaat cagagttttc
    35341 agattgaaga aaaagtccat tttagacggt tttcttcaat ctttttcttt taatcaaaaa
    35401 aacaaaagaa gtctgaaaaa tactgtaata tcagcatttc ccagagtttt catgatatga
    35461 tagtcaattt ctaaatgttc aatttttcta tcgctgatag ggtttgccta cattctgaac
    35521 tccaatcgga gttttttctt tttggcttta gaaaaccttt ggcacagcta atggctccaa
    35581 actggtgatg gtgattcatc agccctctag ggcagcgcct ttgcttctta ctgctgctca
    35641 caccgcaagc tctagcagtg tagtgactgt agctggtagg acagtaagtc cttcttgtct
    35701 cacatcaggc tgctatagcc cctgttctgt gtcttgatcg cctgctctag tgctgtcctg
    35761 ccttgccctc taatgctgct atctagctga ttgacaatgg tctgaatatg atctgcggtg
    35821 tctgtggcaa tccgagatac ctcactgtca tagcgccttt gaagggcatg aaggcgacct
    35881 aaggtcaagg gagcacatat ggactgaact aatctcctat ccagctcttt ctttaaagtc
    35941 ctgatcggct cttgtccggt taagatcatc tctatagcaa tcatctttct tatctccttt
    36001 tccttaacct tcacgccact gacgcctcag cgctgtgatg tccttttcta tcgcctgtcg
    36061 ctggctgcga tagtgatggt caattgcttc ctcctgctgc gacatcttgc gaccttgctc
    36121 atgatagcac tgctctgttc ggtgctggta gtcatcaatc agcctcgtta gaacggtata
    36181 ttggtctgtt atcagactag catcataatg tctgaggtag ctgctaacgg cctgatagct
    36241 agaggcatag agctgctgta gctggttata gttgcctctt aactcgtcat gggctgctgc
    36301 catttggagc cgctcttgat gatagtgctc ctgctgctcc tctagctcct cttccttttg
    36361 acggatagca gttctgatct tttctaatgc tgtcatgaaa agtcgcatcc tagcttttga
    36421 tcaatagcag ctgttctctc aaccccctcc tctagctgct cctttacggt cttgaacttt
    36481 gtggccagtc ctctagcttg agtaaccttg tcatcaaaat gcctcttggt ctgacccaca
    36541 aggctgtcat aggtcac
//
LOCUS       DARYUW010000017        36149 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYUW010000017 DARYUW010000000
VERSION     DARYUW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36149
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            84..1283
                     /locus_tag="TVW11_000728"
                     /pseudo
     CDS             84..1283
                     /locus_tag="TVW11_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            1377..1532
                     /locus_tag="TVW11_000729"
     CDS             1377..1532
                     /locus_tag="TVW11_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1364853.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TVW11_000730"
                     /pseudo
     CDS             complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TVW11_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TVW11_000731"
     CDS             complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TVW11_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1364854.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(3391..3990)
                     /locus_tag="TVW11_000732"
     CDS             complement(3391..3990)
                     /locus_tag="TVW11_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1364855.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(4568..6514)
                     /locus_tag="TVW11_000733"
     CDS             complement(4568..6514)
                     /locus_tag="TVW11_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1364856.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(6511..7422)
                     /gene="pfkB"
                     /locus_tag="TVW11_000734"
     CDS             complement(6511..7422)
                     /gene="pfkB"
                     /locus_tag="TVW11_000734"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1364857.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(7419..8132)
                     /locus_tag="TVW11_000735"
     CDS             complement(7419..8132)
                     /locus_tag="TVW11_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1364858.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(8567..9490)
                     /locus_tag="TVW11_000736"
     CDS             complement(8567..9490)
                     /locus_tag="TVW11_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1364859.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(9502..10560)
                     /locus_tag="TVW11_000737"
     CDS             complement(9502..10560)
                     /locus_tag="TVW11_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1364860.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(10692..11684)
                     /locus_tag="TVW11_000738"
     CDS             complement(10692..11684)
                     /locus_tag="TVW11_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1364861.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(11684..12415)
                     /gene="trmD"
                     /locus_tag="TVW11_000739"
     CDS             complement(11684..12415)
                     /gene="trmD"
                     /locus_tag="TVW11_000739"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1364862.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(12405..12923)
                     /gene="rimM"
                     /locus_tag="TVW11_000740"
     CDS             complement(12405..12923)
                     /gene="rimM"
                     /locus_tag="TVW11_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1364863.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(14198..14437)
                     /locus_tag="TVW11_000741"
     CDS             complement(14198..14437)
                     /locus_tag="TVW11_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1364864.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(14447..14719)
                     /gene="rpsP"
                     /locus_tag="TVW11_000742"
     CDS             complement(14447..14719)
                     /gene="rpsP"
                     /locus_tag="TVW11_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1364865.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(15150..15767)
                     /locus_tag="TVW11_000743"
     CDS             complement(15150..15767)
                     /locus_tag="TVW11_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1364866.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(15760..16983)
                     /locus_tag="TVW11_000744"
     CDS             complement(15760..16983)
                     /locus_tag="TVW11_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1364867.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(16995..17705)
                     /locus_tag="TVW11_000745"
     CDS             complement(16995..17705)
                     /locus_tag="TVW11_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1364868.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(17705..18967)
                     /locus_tag="TVW11_000746"
     CDS             complement(17705..18967)
                     /locus_tag="TVW11_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1364869.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(19282..22458)
                     /gene="carB"
                     /locus_tag="TVW11_000747"
     CDS             complement(19282..22458)
                     /gene="carB"
                     /locus_tag="TVW11_000747"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1364870.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(22876..23967)
                     /gene="carA"
                     /locus_tag="TVW11_000748"
     CDS             complement(22876..23967)
                     /gene="carA"
                     /locus_tag="TVW11_000748"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1364871.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(23990..24925)
                     /locus_tag="TVW11_000749"
     CDS             complement(23990..24925)
                     /locus_tag="TVW11_000749"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1364872.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(24983..26242)
                     /locus_tag="TVW11_000750"
     CDS             complement(24983..26242)
                     /locus_tag="TVW11_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1364873.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(26258..26779)
                     /gene="pyrR"
                     /locus_tag="TVW11_000751"
     CDS             complement(26258..26779)
                     /gene="pyrR"
                     /locus_tag="TVW11_000751"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1364874.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            27141..27755
                     /locus_tag="TVW11_000752"
     CDS             27141..27755
                     /locus_tag="TVW11_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1364875.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(27836..28726)
                     /locus_tag="TVW11_000753"
     CDS             complement(27836..28726)
                     /locus_tag="TVW11_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1364876.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(28716..29174)
                     /locus_tag="TVW11_000754"
     CDS             complement(28716..29174)
                     /locus_tag="TVW11_000754"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1364877.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(29402..30331)
                     /locus_tag="TVW11_000755"
     CDS             complement(29402..30331)
                     /locus_tag="TVW11_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1364878.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(30738..31031)
                     /gene="rpmA"
                     /locus_tag="TVW11_000756"
     CDS             complement(30738..31031)
                     /gene="rpmA"
                     /locus_tag="TVW11_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1364879.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(31053..31385)
                     /locus_tag="TVW11_000757"
     CDS             complement(31053..31385)
                     /locus_tag="TVW11_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1364880.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(31398..31712)
                     /gene="rplU"
                     /locus_tag="TVW11_000758"
     CDS             complement(31398..31712)
                     /gene="rplU"
                     /locus_tag="TVW11_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1364881.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(31746..31820)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(31942..33135)
                     /locus_tag="TVW11_000759"
     CDS             complement(31942..33135)
                     /locus_tag="TVW11_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1364882.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            33400..34017
                     /locus_tag="TVW11_000760"
     CDS             33400..34017
                     /locus_tag="TVW11_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1364883.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(34315..35544)
                     /locus_tag="TVW11_000761"
     CDS             complement(34315..35544)
                     /locus_tag="TVW11_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1364884.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(35579..36091)
                     /locus_tag="TVW11_000762"
     CDS             complement(35579..36091)
                     /locus_tag="TVW11_000762"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364885.1"
                     /translation="MDKSDEVLMQLKSEVNLGLNGLAGVLFYLSSISYDNEIIEKGID
                     FILESLVEDSDGNRGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSESLL
                     VEFAQFSGLWNGMLGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYEFR
                     YAVSIFNQVK"
BASE COUNT        11007 a         8273 c         6365 g        10504 t
ORIGIN      
        1 cattaacatt attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa
       61 cggtatcgtc acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta
      121 gcaacaatgc tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac
      181 gtttaatcaa atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat
      241 taaatacgtt gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag
      301 gaacgaacct cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta
      361 taaatcagtc tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc
      421 aatccacact tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc
      481 agcagatttc agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac
      541 caactggtaa tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat
      601 aaacttccac gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat
      661 catccctctc tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata
      721 acagttcaga aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac
      781 agctgtcaac catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg
      841 tatagttaga cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg
      901 aatacgaggg gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata
      961 ttactcaaac tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc
     1021 ttaaaaaagg tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg
     1081 ttaatggaaa aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt
     1141 tcaagattac aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg
     1201 cacagggtcg tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata
     1261 aactgttgtc aaatcatgat taaaccattc cggacgtttc gatgaccatt taggatttag
     1321 agaaataata tattgatctt aaattataat attagaaaaa agaaggaggt ccacaaatgg
     1381 aaaaacaaaa ttcactcact caatttcaag aactaaattc atccgaactc aatcaaataa
     1441 caggtggaga ttggtggtca gagatattaa attttaatcg ctctcaaaaa tataaacata
     1501 cctccgtggg ttctaataat attattgtct aacatatact tagtattgta ataatagttt
     1561 ttttagtaga aatcataacc acccgtccaa caggtggttt gaatagggac tataaaccca
     1621 tataactagc cagcgcctaa agacgctggc tttcactttg ttcaaaccac attgctattg
     1681 actcgtcact tgcctctcaa agaagtattt gtatcactta cccttatctc taaagggatc
     1741 ctcatattct tttacactca gtttatctag tgctatgtca tgtttttctt gttcttgaat
     1801 atattttttt attgtagctt catttaatcc aaccgtacta atataatagc cttctgccca
     1861 aaagtgtcga ttaccaaatt tgtatttcag attggcgtgc ttgtcgaaca tcataagcgt
     1921 actcttacct tttaaatatc ctataaaact tgaaacactt attctgggtg gaatgcttac
     1981 taacacgtgt acgtgatctg gcatcagatg tccttctata tatttctaca cctttatagc
     2041 tacataatct ttgaaaaatt tctcccaaac tgcctcgata ttgattatag attacttttc
     2101 gtctatactt aggggtgaac acaatgtgat atttacaatg ctactttgtg tgcgataaac
     2161 tgtggggctt ttgtgccata tttttactcc tttcgcttta caattggctt gaacacctat
     2221 attgtagcgc gtttggagtt tttttgtagt ataacgttcg atgcgtaccc gcatagcggg
     2281 ggatttttgt ttcgcaccta cggagcgaaa cggactaaag tcactaagtc ataaccacgc
     2341 gtaaaaacgg gtggcttgta caccggctat aagccgtttc tctccagcga cgtctaaaga
     2401 cgttcgctga acttcgttca ggttagtgct atgattactt gactaatgcc cgtaaaaacg
     2461 ggcttttatc ttgttttaaa actgccatct gaaaatggat cttcatattc tttaacactc
     2521 aacttatcaa gtgcaatgtc atttttctcc tgctcgcgaa tatatttcgc taccgtcctt
     2581 ttgttcagtc caacggtact aacatagtag cctctagccc aaaactttcg atttccatac
     2641 ttatatttta aattagcgtg tttatcaaat atcatgagag cacttttact tttcaaatac
     2701 cccatgaaat cggaaatcga aagttttgga ggtagcaaga cgagcatatg aacatgatct
     2761 ggcatcatat gtccctcaat gatttccacg cccttgtatt gacataggtg acggaaaata
     2821 tcaattaagt cctgtctaat tttgtagtaa atggattttc tgcggtactt tggtgtgaaa
     2881 actatgtgat atttgcacat ccatttggta tgtgataaac tgtaactggt tttagccatc
     2941 tctttttcct ccttgatcta acctgaacaa ttagattata acaggaaaaa gaaatggaag
     3001 ctcaaagcct tgtcagccac cagcatagct ggtggttttc ttgtttttct ctacgagaaa
     3061 aactggctcg aagccataat gaatcaaaag aagatagcat ttctgctatc tcactgttag
     3121 ccactactta caggtaaaaa tacaccttgt ctatttgtag tttaactatc catttaatcc
     3181 atcaataagc caaaccagac cgtttaatca tctacccagc cttacacata gtattttctc
     3241 acatcatttg tagaattgct ttctccttgc atgtcaccat ctcgtcttaa acgttcgtaa
     3301 agggctgttt gatcttttct aactatttta gaaaattatt ttgctgttct gatgaggtta
     3361 atctcgttag atcagtcatg ctggaggtag ctaccgtatg ggagcgtcaa aataagtcag
     3421 ctgataatcc cctataatac gattgagctt ttcgccatag ctagtatctg tggcatatgt
     3481 gcctgttaaa ctagcggtgg cctgctgata acttgtatga atacctcggt gagtagggcg
     3541 ataaagcggg tcactcaaaa ccctagcata atcctcaaag caggctgtta agctgccata
     3601 ggaccgaaaa gaagcgtcaa ttagataaag gttgccttgg ccatcatctt ccaaggtagg
     3661 taaaataact gattttcctt tatagcttcc tttgatacca aaaaaattat aatagggctc
     3721 ttgacttagc ttagattgac catttgctga ctccaaaata gcctgtgcca tcatgactga
     3781 ggcatagagc ttgtttcgct gcgcaactgc ctgagcggaa tgactaatct tgctcacaaa
     3841 tagcatggtt gagctattgg catgaggctt aaggtgatcc ttagctgacg ctaaggtcca
     3901 aaggctaagc aacatgctgc ctaaaacaat accagcagcc agccaagagc tagcttccct
     3961 gtggcttctt ctagctttcc tcctcttcaa cagaaatatc ctcacttcct tgcttttaaa
     4021 cctagtatag caaaaattaa aagcaaaatg tagccagacc acatgctcac ctcaaaaaca
     4081 ggccttatga cttctaaaaa gacctagcag ccacaacagg cgcataaaaa gtttttaaca
     4141 agaaaagaag actttgctgt atttcaatcc acgctcctgc aaagggagcg atacaaaaaa
     4201 taaatggaat atctacaatc aaatgatttc aatgtttagc tatttcaaga atatatctta
     4261 tttttgatag atgttactat aggaaaaacg ttgatagtat ctactttaat tgatactata
     4321 attcgaaaat aactgtttcg cacgtttggt gtggcttagt ttagcagggc tattgggtca
     4381 ctgcttagct attctagatc agattgattc tctctaaata ttagcttttc gccagtcatc
     4441 actactagca acaaacaaaa cgcacgacat catgtaaaaa caggctgatg tcatgcgtct
     4501 gatgttttat taagactagg tctaattcag aagctttccc tagtacttgt ggctttatag
     4561 ccagtaacta agctttttta cgaagtgcgc caaagagaat accagaaacc actgctccaa
     4621 tagcgacaaa caataggtat aagaaaggat tgcttgtcaa agcgataacg aagataccgc
     4681 catgtggtgc gattaatttg acacctgcta gaccaacaag agcacctgtt agggcagagc
     4741 cagcgataaa gcttgggata gcgcgtgctg ggtctgctgc accaaacgga atggctcctt
     4801 ctgtaatgaa ggaaagtccc ataataatgt tggtcaagcc agattcacgc tcttccttgg
     4861 taaatttgtc tttaaataag agtgttgcca caaaaacagc tagaggaggc accataccac
     4921 ctgccatgac agcagccata acaactgacc caccgcttgc aacggttgca gcaagtgttc
     4981 ctgtaccaaa gacataggct gccttattca ctggaccacc catatcaaca gccatcatgc
     5041 cgccaacaag aagtcccata agaactgcag agctacctga cagactttct aagaagtggt
     5101 tcaatgctgt attgatagct gccataggaa tattgatcag cagcatcaaa agacctgtca
     5161 caagaacacc aagtaatggg taaagaagga ttgacttgac cccttcaagc gaacgcggaa
     5221 gccctgcaag cacttgacga agagcaagaa ttactccccc tgcaaggaag ccacctacaa
     5281 gcgcaccaag aaatccagac ggtactcccg ctaatgatag gctagcctca ccgccagcag
     5341 caaatggaac ctttccaaaa gcaagaccgc tagaagcaat ggcacctgcc acaaagcctg
     5401 ccacaagacc tggcttttca gcgatagaat aagcaatgta gcctgctagc actggcaaca
     5461 tgaatgaaaa ggccgcacca ccaatatgtt taaagatagc tgctatttca tggtaggatc
     5521 ccaaattaga cagctgatcc tttggtaccc caagcatgtt gtcaagcaag aaggcaagag
     5581 caattaggat tccaccacca attacaaatg gcagcatttg tgatacacca ctcatcaggt
     5641 gcttgtagaa ggctccgcct aggcttgtct tttgagctgc ttttgcttgt tcagcagcgc
     5701 cattcttggc atgataaaca ctaccagcat tgtttaaaat cagtgaaatc aattcctcgc
     5761 ttttcttaat accatctgct acaggacgag caatcaattg cttaccatca aagcgatcca
     5821 tctcaaccgc cttatcagca gcgataatca ctcccttggc ctgcttgatg tcatcagctg
     5881 tcaggcgatt gccaacccct gaagcaccgt tggtttcaac cttgatgccg acacccatct
     5941 gtgcagcctg ctttttcaag gcctcttctg ccatataagt atgtgcaata cctgtcgtac
     6001 aagctgtcac agcaacgata aactcctgag catttgtagg aacaaaagct acctctttct
     6061 gatcagaagc cgcatcaaag acagcaatca cttcgtctgg acttgttgcc tttcgcagtt
     6121 gatctgcaaa gccatccttt aataggtatt gggataattc ggctaaggcc gctaagtgag
     6181 tatcatttgc cccttgaggt gctgcaatca taaagaacag atcagttggc tgaccgtcta
     6241 aggatttgta atcaacgccc ttgttagatt ttgcaaagag cactgctggc tggtcaacaa
     6301 caacattttt tgaatgcggc atagcaatgc catcgccaag acctgttgag gtttgctcct
     6361 cgcgagctaa gatactcttt ttaaacacat caaagtcatg tacaatccca tgctctacta
     6421 gttctgtaat catttcatca attgcagcct cttttgaaac agcctgcaaa tcaagaatca
     6481 tgatgtcttt tcttaataaa tcctgtattt tcatcgaacc tctacctcaa cctcattata
     6541 tgttttttta atatcatcaa ttgctgctaa atcatctgaa aaagcagttg ctgttccgca
     6601 ggccactccc cattttagag cctctagcgg actatgactt ttgacaaagg cacctgtaaa
     6661 gcctgccacc atcgaatcac cagctccaac agaattcttc acctgccctt taataggctt
     6721 agcaaaataa gttgcttcct gagtgaccag caaggcacca tcaccagcca tcgaaacgat
     6781 aacatgctgc gctcccatgt caaggacctt acgagcatat gtttcaacgt catctagccc
     6841 atttaagctg acgttaaaaa tagcttctag ctcatggtta ttaggcttta cgagcaatgg
     6901 gtgatacgcc aatgcatcta gcaaggtctg tccttcaaaa tcacagacca cctgtgcccc
     6961 agcttgtctg accaatggga tcaagtcctt atagacatca ttgcctagac ttgaaggcgc
     7021 tgagcctgca aaaacaacaa tgtcctctgc tgacacattt gccaatatag cctttaaatg
     7081 atccaattgc tgctttgaaa tcactggtcc aaggccatta atctctgtct cctctgctga
     7141 tttgatctta acattgatcc gcgtatcctg atcaaccgtt acaaagtcag tattgatgct
     7201 ctcagcagct agactttcct taataaaacg cccagtgaag ccgcctaaaa agccagtcgc
     7261 tgtattatca atgcctaatc gctgtagaat gcgactaaca ttaatcccct ttcctcctgc
     7321 aaatgtatcg tcactgacca tgcggttaac cgctccaata tctaattggt ctattctgac
     7381 aataaagtct atagaaggat ttaaggttac tgtgtaaatc atagtgcaat taccttcgct
     7441 ttttccttga ttttcttcag cattactgtc gaagatttct ctgtaatgat ttcaacccta
     7501 tcaattggag caaccttgac aaaggaaaca tgaccaagct ttgttgcatc agctaataca
     7561 taggtgattt tagcattggc aatgacagct tttttaataa cagcctcctc catatccgga
     7621 gtggttaaaa atgcctcatc gataccattg ataccaagaa aagccttatc aaaattcatt
     7681 tgcctaattt gctccaaggc aacatgaccg atgcttgcgt ctgttgtctg cttgacatag
     7741 ccaccaataa taatggtctt gatcgccata tcaaccagtc tagtcgcatg atgaatagaa
     7801 ttagtcacta ctgttacttt ttttaattgc aaaaaaggaa ggagaaattc ggttgttgtc
     7861 ccagcatcaa taaagatgac atcattatca aaaaccagct ctgctgcctt ttgagcgatg
     7921 atttctttta tttgactgtt tttgacagat ttttcctgat tagataattc ctcttgtaag
     7981 gaatgaaaaa gctcggcacc tccatgcact cgatgaagct tgccctcacg ctccagctca
     8041 tctaaatctc tacgaacagt tgattctgac gagcttaaca gctgcattaa atcctctagc
     8101 gcaacgtaat tctcagctgt gatttttgcc ataatgagct gttttcgttt tgattttaag
     8161 ataaaaccac ccctttgtct gaaatcgttt acagctctat tatactacac tttattccaa
     8221 agtcaagcac tatctttcaa aaacattcaa attcaatctt agacctctat tgccttaaca
     8281 ataactgcca attgatcagt cattgtcccc gtcaatacct gtagactaat gattaacgac
     8341 ttttttatta actagagccc aaaaagcgct cacctgttgc aaaagtctga aacacaatag
     8401 tctcttacaa atcaaaaagc aacggattta ctgtcgttgc ttcataatga gagtctagga
     8461 caaagtcttt tcagccaaca agacaaaacg agagagtcac ctattgtgag cctctcgttt
     8521 tattgtactg agaaattgtt ttatcccaga ctccttatgt ctaaacctat ttgatcttca
     8581 aaatattctc tttggcatgg actagctgtg taatcaagcg gcaataaggg gtatcgatac
     8641 caagcttttc acccttggta tttaccgcac cgttgataaa gtcaatttca gtcaagcggt
     8701 gattttgaac aagatcctga tgcattgatg ggtagtgatg agcagccttc actgaggttt
     8761 ccatcacata ggctgtgatt tcctcttcat taagctccac cccctcagca cgaccaacaa
     8821 taacaaactc atgaatgatt tctttaacca tgtttaaacc atcttcgctg gcaaataact
     8881 caccaatcgt gcaatcaagt agggcacagg ttgagttcat tgtaccattg acacaggctt
     8941 ttctccaaat atttggaaca acattatcat cataagttgc attcaattga gcgtcattta
     9001 gcaagtcagc aatctgatgt cctgcctctt ggtttgctgg atccatgctt tgtagattaa
     9061 gcgcaccaac tccttgtaag tgtacctgac caggtccctc aagacccgct gtccaaacgg
     9121 taacacccat taaaatatta tgctctggaa tatagtgacg aatcacatct tcgtgtccaa
     9181 gaccatttaa taggcaaagt accttggttt cagggccaat aataccttta atatcagtca
     9241 gcatttgtgg cagctgcatg gctttggtaa acaaaatgat aaggtcagct tccttagtag
     9301 cctctgtcgg cttcatgata ggaagcttta cggtttcctc tacatcgcct gaaatcttca
     9361 agccattctc tttgatcgct tgaagatgtg cttcccaatt atccagtaaa ataacgtcat
     9421 tgtttgtttt tgaaatttgg taaccaaatc gacagcccat agctcctgag cctgcaatat
     9481 aaactaacat gctttttcct cttatccttc aaatacaaaa atatcttctt tataaagctt
     9541 taaaatatcc ttacaaagct tatgtgccac aaaagcaact ccaaatggaa tgaccaacca
     9601 agcaatgata atgatcacaa tattgctgcc accggcaagt gaagcaatag gaccaactgc
     9661 accaacaaga ccaaagccag atgaggctgg tgttccaatc agattaaaca ttggaacggt
     9721 taaagagcta acaatagctg tcatcatcat tggaatagcc ataactgggt attttaagaa
     9781 gtttggcatc atcattttca tagcgccaag ggcaatggca attggaacac ctgatttgtt
     9841 aacctttaac gttgcccaca caagaacagc ggttgttgaa gcaataccca ttgaggccgc
     9901 accagctgcc ataccattta agccgatagc taaaccaatc gcaaccgttg agatcggact
     9961 cacaatcaaa agagcaaagg caatggcaat caaaatagac atcagaattg gctgaagcgt
    10021 tgtaaatgaa ttaatgcctt ggccaatcag ggtcgtcaca taagaaacgt aaggaagcag
    10081 cttccagcca atgtaaccca cacctgttcc aataataatt ggcaacaaaa taatggttag
    10141 agacccaaat ttatcaccaa accacttcac tgctaaaacg gcaagcgcag ctgtgatcat
    10201 catattaatc agatcaccaa tgccctttag ctggaaggtc ccagtggcaa cacctttttg
    10261 gataacctct gtataagccc aagctccaga accgatataa gctgccccgc cgacagccag
    10321 ctgctgcatt gggttaaatt tgaactgctg tccaatcaaa aaaccagcca taactggcgt
    10381 aaagaattgg aaaacctgga cgatatgtaa aaattcagct gctacagtat ttggcaaaag
    10441 cggctttaaa aacgtcgcta aaatagcatt cggaataagt gcaactacaa tcgcaattgc
    10501 tgtaccagct aagaccttat tcataaacga gctaaaggtc tctttatttg ttgttgtcat
    10561 ttcatgacct ctcttaatat tatagtgtga aaaacatcac gaaagtattc taacataaaa
    10621 agagcatttt gtcacagcta ttttaatttt tatcaatacg tacagaatat tcaattaaat
    10681 gtcatataat attaatcaat caaggctgtt gaatgaacag gtctattatc tctatcagga
    10741 taaatatact taatcgcttg gttgacagca atcggtgcct caccaaagcc agtggcaatc
    10801 aaatcaaccc tgccttcata agctgctgcg tcaccgatcg caaaaatccc ttcctgactt
    10861 gtttgaaaga ggggagagac aagaagactt gagcgcttat aatctagatt ccaatgcttt
    10921 aggtttttat tagatgtaga aaagccaaag ctaacaatca ggctgtctag ctcaagcgtt
    10981 atctcctctt ctgactttac cttttgaata gtcattttgt tgacaaagcc attttctcct
    11041 tcgagggcaa ggggaacaaa gggggtaagg gtagtaacat gagagttttt taacaattct
    11101 acgctatgct catgagccct aaaggcgtct cgccggtgca caagggtaac actcttagcg
    11161 aggccatcta aggctaaagc ccagtccaca gcagaatctc caccaccgca gatcacaacc
    11221 ctcttaccag caaactgatt caagctgtga acattataaa agagattatg atcagcaaat
    11281 aactgctcat tgtctaagcc caaggttcta ggcgcaaagg ctccattgcc acaagcaaca
    11341 ataatggcct tagaataatg tctggccttg cttgtttgaa taacaaagtt cccatcagcc
    11401 ttctcaaaag acaggacctc ttctttcagg catactgcta tgcgatcgtc aaatctgctt
    11461 agctgctcaa taagcttttg tgttagttcc gctccagtca gggccggata agctggaata
    11521 tcatagataa ccttttcagg ataaagaaca gccggctgtc ctcctagctc tgacaggctt
    11581 tcaataatct taaccgtcat gccgcgcagg cctgcataaa aggctgcaaa taagcctacc
    11641 ggacctccac caatgatggt aatgtcatat attttttctt gcactagttc tctccttcac
    11701 ttagccccga tttgatttta tcaaaaatcc ttttttcctc atcagaaaaa tcataagtct
    11761 ctaataaatc tggtcttctc aaataggtct tctttaggct ttgctccata cgccagagac
    11821 gaatatgctc atgatggcca ctcattagga catcaggcac cttcatgcca cgataatcat
    11881 atggccttgt atactgtggg tactccaaga gcccagatga gaaggaatcc tcttgatgac
    11941 tggcttgctt tccaagcaca ttaggaatca gtctcactgt tgcatcaatc attgtcatag
    12001 cagccagctc accaccagtt aagacaaaat ctcccagaga tatttcatcg gtaacaagtg
    12061 tcttaatgcg ttcgtcatag ccttcgtaat gcccacaaat aaaaattaac tcttcctcaa
    12121 gagctaattc ttcagcataa gactgatgaa agggttttcc agcaggatcc agtaaaatca
    12181 ctcgaggctt tgtagcctga atgctatcca tggtatcaaa aataggctgc gctctcagca
    12241 gcatgccctg cccaccacca tatggctcat catcaacatg cctagctttc tccgcatggt
    12301 cacgaaaatt gtggtaatga atatctaaaa gccccttttc cttagccttt ccaacaatgg
    12361 agtgctccaa aggagcaaac atttccggga aaagggttaa aatatcaatc ttcatcatct
    12421 aagccttcca taatttcaac gtctacccga tgcttttcga tatcaacaca aagaacaacc
    12481 gatgggatat aaggaagcaa caggtcacgc ttgctttgcc gtttgaccac ccaaacatca
    12541 tttgcaccag gctgtaaaat ttccttaatc tctcctacta gctggtcctt ttcatacacc
    12601 tccagaccaa taatctggtg atagtaaaat tctccctcag ctagcttacc ctgattctct
    12661 ttagcaatct taagactgta gcccttaaat tgctcaatag cattgatgtg atacattccc
    12721 ttaaacttga taatgtcaaa ctgcttatgc ttgcgatgac tcgcaatctc aacctcctgc
    12781 acaaaacgat ccttgtcgtc aaacagggct agtctagcac ctttttgaaa tcgttcctca
    12841 gtaaagtcac tcacagacag cacgcgcatt tctccttgca agccttgagt attgacaatc
    12901 ttcccaacgc taaaatattc catccttact cctaatcatc ttagactcta tagcttgata
    12961 gacctctatt ttttcatgac aacacgacat gagtatcatc atcctaagca ctctagccta
    13021 tcgttaaagc tccccttatt gtaacatgtt ctgccttatt ttgcacttct ctttcaaaaa
    13081 attaatctcc cagttatagc agctaagcct agcaagcaaa gcccttgatg ctaaagaatc
    13141 ctgatccccc tataattaac aaatcatcat gacttgcctt gcccaagctc agtcaagtga
    13201 atgaaaaatc tgctaaacaa tagccttgcg cctcgctgac aagcatcaaa aaaacactcc
    13261 tgctggcaat ctgaactgcc ccccaattgt tagattttat gtccaacttt tgggggtcag
    13321 tacaatctag taaactagaa tcaggagtgt ttcattatag cccaacaagc aaaaggaata
    13381 cttggtaaaa gcaaagctga cttgcattga gaagattaaa accattcaat ctgtcacaat
    13441 aattatggaa acattgggaa tttaaaaaca agtatcagct gctatcaacc tgtggggaaa
    13501 tagtctacct atgcctatcg ggccatccat cataggtcct ctcaagaaat gatgagagcc
    13561 tcatcaacca gctatcatcg ccttaaagga gaatgacgaa tgttatcgta ggtgtcccaa
    13621 gaaatactac aaaagaaact cattttgatc ttaatgctct aaagggcttg accttacgtc
    13681 aactgataaa gctctacttc atagcatcgt tttgctttgc agcttttcta tacctcatgt
    13741 ctaataaaag acataagctt gccgataaga acattacccc aacatagaag aatagattgg
    13801 tctcatcgcc agtctttagt aagatggtat tttgatgctt catcggtttg gtagctgttg
    13861 aaacatgcgg acacttggtt tcatttgtcg tcgatggtat tgtcggacga cttggcttag
    13921 tgttattagg cttatgattg ccttcactac tgcttacctt tttcttccac tgtgcaaaca
    13981 attcattagg aaacggcagg tcattatcta ccctaatgtc atcacctacc ttttttaacc
    14041 tcctgctcga tctcttgttg catacaaaat gttatacaga tacttctgtc agatagagtt
    14101 cttgcttttg tctcttgact tggtgattca aaacacaaaa aaagcctgct agatagaact
    14161 agcaaggctt taagattagt cttgttcaaa atagaactta tttttcatca atgactaatc
    14221 gaaccttttt tcctaaagtt ggcaccgaat agacaatcga tcttatcgct gtgatggtac
    14281 gacctttctt tccgataaca cgaccgatgt cttgagcatc caagtcaaga tggtactcta
    14341 aaaaatccgg agtatcttca attttaatag taagcttatc tggttgtgaa atcaagggct
    14401 tcacaatagc gataatgaga ttttcaatgg tatccatagg cttttattac ttagaaaatt
    14461 tttgatcgtg gaatttagcc ataaccccag ctttagatag aaggctacga actgtatcag
    14521 aaggttgtgc accttttcct agccaatcaa gaacacgatc ttctttaaga gttacttgat
    14581 tttcagctac aagtgggttg taggttccaa ctgtttcgat gaaacgacca tcacgtggtg
    14641 cacgtgaatc tgcaacgttg atacggtaga aaggtttttt cttagaaccc atacgagtta
    14701 aacggatttt tactgccatt ttaatatgtc tcttttcttt aaatgataat agtcaagaaa
    14761 tgtagtcctg ctcatttctc acctaactag tatactttac ttttgattat gtgtcaagtt
    14821 tttttcttga cactttttta tgatcataat actactcaac atcttcaatc agctaagctg
    14881 cttagatgac atcaaacagc aggcagctgc tcttataaga gcatacaact ccaaactaac
    14941 ctactctagt gatccttagc cgtcaataat gggatcaggc aagcataact ccccgtcaaa
    15001 ggagcggttt gtttcacagc aaaaaggcga aataaactga caatcacatc aaaaaggacg
    15061 agcccctaaa catgcaggag ctcgtccttt taccaatatg acttagtctc tccttgcttt
    15121 taaggctagg gtattagcta agcgttacac taataatgca tcaaaatatg cttaagaaac
    15181 tctccaccat aaatccaaaa ataactgaag gtcaaaattg aaatgggtct acaaattagg
    15241 ataatcagta aaaagcgctt gtaggtcatc tgactcaatc cagtaatcat aataagagca
    15301 tcggcagggg ctaaggggga aatcatattg agaataaaga aacgctcaaa taatttcgtt
    15361 gatagcttct tttcataaaa ctgtagctgc tccatactta aaaacagtaa gataaagggc
    15421 tttccgtatc tcctcaccaa ctgaaacaaa atagaagatc caatgcagat accaaacaca
    15481 tttaacataa agcctaatat aggaccaaag gctagaaagc caacgactgt tgtcacacca
    15541 ccaggaatga taggaacaac tacctgcaca atttgcaaga taaaaaagca aatggcaccg
    15601 ataaggagat gatccttgat taaatgggct aaagcctttg gattattaat aatatctagc
    15661 tgcctaataa ggtagacaac aagcatgacg gagaacagaa ttgataggcc accaagaatc
    15721 ttaaacagct tctttaacaa cgaatgtgaa acaccaaagc tactcatagc gcaaagcctc
    15781 tatcggatca agcttgcttg ctttgtttgc tggcagcaat ccaaaaataa taccaattga
    15841 tgccgaaaag ataatagcta cagccgcaac atctaaggaa acagctgctc cctttaattg
    15901 catcgcattt cctagcacac ctacacacat ctgtgctagc agcagcccta aaagaccgcc
    15961 aattaacgtc aacaccactg attcaatcaa aaattggcta agtatcttca agcgcgttgc
    16021 tcccaaggct tttcgcaagc caatttcacg tgtacgctct gttacagata ccagcatgat
    16081 gttcataaca ccaataccac ccacaagaag ggaaattcct gcaatggacc caacaactgt
    16141 ggtcatgata ctaaattgtg cgttaatgtc attgataatt tggctattgt caggaacagc
    16201 gtactcgccc tccttaacat gagacagtgt ggtcagcata gcagctgctt gatttcctaa
    16261 ttcaaggctt cgcttaacgt cgccaatata aagataaaca gagccaattt ccttgacatg
    16321 aaattctgaa gccacctggg tattggccat aatggctcct ccagaaatcc caccagcaaa
    16381 cgaaacaacc tcctgatcag tcttgtaaac acctactaca aggtagtcct tactatctag
    16441 actaaccacc ttatttagag cttgttcata attgcctttg ccaaataatt cgtcagccaa
    16501 gacagtatct aataggataa tgcgagaaaa atttttataa tccttgctat ttagcgtcct
    16561 acctgcaaca atatcatatt ttttgacttt aaaataatcc tgactaaccc cagtgatggc
    16621 cacattgtcc atcttctttt tctcaaagga aatggtagag gttgaattat tggtatagta
    16681 ataagaatct accccatcaa ttgctttgac aatctgctct agccattcag gcttgacctc
    16741 ttgctcattt tcatgcgctg caaaggccgc gtaagggttg tcctcatctc cttttgcctt
    16801 gaaataaagc tgaacctctt tttggtcatt tgaaaaggaa tccgtaaccc tctttgtcat
    16861 ggcagcacca agccccatga taatcacaac agcagctaca ccgataataa ttcccagcat
    16921 ggtaagaatc gaacgcagct tgtgccccca gattgaacta agagcaaatt tccaattttc
    16981 catcactttt cctcctagtc aatcctgaca ctttctgttg tatcagctgt gatttcacca
    17041 tcacgaataa caatttttcg agtggcaaag tccgcaatct ctggctcatg agtaaccata
    17101 ataatagttt tgccttcctt attcagctcc gtcaaaagcc tcataatctg ctcaccagtc
    17161 tttgtatcta gggcaccagt cggctcatca gctaagataa tagacgggtt attaaccaag
    17221 gctcttgcaa tggcaaccct ttgcttttga ccacctgata actctgatgg caaatgcttc
    17281 attcgcatac caagctcaac cttttccaaa aattgcttag ccaattcacg acgctttgat
    17341 actccaactc cagcataaat caagggaagc tcaacatttt gcagggcatt tagctttgct
    17401 agtaaaaaga actgctgaaa gacaaagcca atctcttcgt ttctcacctg agcaagcttt
    17461 cgatcattta ggatctcaac ctgtgtgcca ttgagacgat aatcacctga ggttggtcta
    17521 tctaataagc cgatgatatt catcagggtt gatttccctg agccagaagg ccccataata
    17581 gcgacaaatt caccctcata tacagtcaaa tccacgcctt ttaggacctg tagctcctga
    17641 tcaccatttt gatagctttt aacaatgctt tttaattgta ttaattcttt tttctcatct
    17701 ggcactactt aatcacctcg gattctttac tgcttttttt agaatctttt gatgcctttg
    17761 tgtctgcgga aataacgtct tctagctttt caccctcttt gatgttctta tcagggttag
    17821 caatgacaat atctcccacc tttagacctg cacttacttc ttgtctttca gcatcagcat
    17881 tgcctagggt tacttcaacc tttttagcct ttgcagttga gtcatcatag acccagacaa
    17941 aatgcttctt gcctttgtta acgatagcag taactggtac taaggcatgc tttgcttcgt
    18001 tgataacctc aacagacacc gtaaagcctt gctttagctg gttaagcgga ctcgtgatat
    18061 caattttgta gtcataggtc gcaccagttg agcttgatga gcctgagcct cctgcagttg
    18121 aaccacctgc attggcatcg gttgggtagt ttgacacata agaaatcttt ccggtccact
    18181 cttgatcagc atagaccttt gatttaatct tcacagcttg tccaacctta atattggcta
    18241 aatcatactc tgttagggtc cctttgacct gtaacttgcc ttcggttgcg acatgaacca
    18301 aggtttgact gttttttgaa gacgggtcaa tatcattatt aacctctaca actgtccctg
    18361 aaacaccact gacaactact gtttcattta aggcctgctg tgctttattg acctctgctt
    18421 gagcatcagc ataggaatca tttaaatcct gcaattgctg agcatagcta gcattttgct
    18481 gggctgaggg ctgaatggtt gtggtggttt cttgccctgt ctcctcgtcc ttgcttgtct
    18541 cagtagttgc tgctggaaca ccatacgttt ttaaatgatt aatctgacgc ccaattttat
    18601 tgagattgcg aacagcggtg tcataagctg cctgtggtac agttgtattg tactgtacta
    18661 actgctggcc ttgtgtgacc tgatctccta ccttaaccgt aacggtagcg tctgagcctt
    18721 tgctagcatc aaaataaaca tattcttctg aaagagcttt aacagtacca gagagtaagg
    18781 ttgaagaggc tattgtccct tctgttacat ttaccgcaga ataaggtagc ttgatatttt
    18841 gatcagagat agtatcttgc tgttgcttcc acaatactcc accgataacg actacagtta
    18901 gtgcaactgc acctgcgata atgcctttgg ttttcgttga taactttatc tttcctcttt
    18961 tagacatttc tgtcctcccc ttttgtacta tttttgtaag acaagtatat gatgttttta
    19021 aaaacttgtc aagaatttct tggataagct taataaagca gcctcttcat catgtagatg
    19081 acaactctat tataatggtt tttcaagctg tactagctta cacttttgta atattaaaaa
    19141 gaggcaaaga caaaaagagt tgtcctttaa ctttattaca cagtctcatt cattaaaaag
    19201 cgaacaagcc tagttttcaa aatctcagaa aactagactt gttcgtttgt ttagactttt
    19261 ctctcagtct cttcatcagg tttaaatagc ttctatacta aaggtacggc tttcaagaac
    19321 tctcagcatt gctactgctg tatccaatgc tgtaaacaga ggaactcctt gttcgattgc
    19381 tgagcttctg atcatctgcc cgtccttatc agtcactcgt tttgttccta cggtattaat
    19441 aatagcttga atctgccctt ttctcagtaa ggctgggata tcatgagcat tgtcgccaat
    19501 ttttccaact agctgtgaat ctagcccttg gtcagcaaag aaagcagctg tgccttcggt
    19561 tgccatgatc tggtagccaa tagcactaaa gcgtctagct aagatcagag cctccgactt
    19621 atggtcatca gcgatggtaa aaactattgt tccatattcc ggcatgtgca gatagctagc
    19681 ttcaaaggct ttgtaaaggg ctttttcaag tgttaaatca gagcccatga cttcaccagt
    19741 tgatttcatc tcaggcccta aaaggctatc caccttagcg agctttgcaa atgaaaaaac
    19801 cggtgccttg atatgaacaa gcgagctttc aggataaagg ccatcttgat aacctaagtc
    19861 ttttaaggtc tgacccagaa taagcttcgt agcgacttgt gccattggaa tattggttac
    19921 ttttgataaa aatggcactg tccgactggc acgaggattg acctcaatga catagacctg
    19981 ctcattttgg atcacaaatt ggatattcat catgccaata cagtttagcc ctatagcaag
    20041 acgcttagtg taatcaacaa tcttgtcttg aacctgttta gataggtgct gcggcgggta
    20101 cacagccatt gaatctcctg aatgcactcc tgctctttcg atatgctcca tgatccctgg
    20161 gattaagact gattgaccgt cagagattgc atctacctcg cattccttac caaggatata
    20221 agaatctatt aaaacaggat gctcaggact agccttgaca gctgttttca tgtaggagcg
    20281 taaatcgttt tcattttcaa caatttccat tgctcggcca ccaagaacat aagagggtct
    20341 gaccaatacc ggaaagccaa tggcacgcgc tgcctctaag gcctctgcct cattggtggc
    20401 tgttttccca ggaggctgag ggatccccag ctccttcaag gctttttcaa aaagctccct
    20461 atcctcagca caatctaagt cctctagctg tgtgcctaaa ataggaactc cggccttggt
    20521 taactgctct gctagattaa tagcagtttg tccaccaaac tgtaggatta ctccctttgg
    20581 ctgctctaat tcaataacgt tcatgacctc ttcaaaggtt aagggttcaa aataaagctt
    20641 gtctgatatc gaaaaatctg ttgacactgt ttcaggattt gaattcatga taatggcttc
    20701 atagcccgca gcctgaatag ccttgacaga atgtacggtt gcataatcaa actcaactcc
    20761 ctgaccgatg cggataggac cagagccaag gacgataaca gattctttct cggatttgat
    20821 tgattcgttt tcccactcat aggtcgagta aaaataaggc gtttgtgagt caaattcagc
    20881 tgcacaggta tcaaccatct tataaactgg caagacacga taggctcgcc ttaaccgtct
    20941 aatacttgca gcatcagttt gccaaagctc tgcaattttt tggtctgaaa aaccatatcg
    21001 cttggcttct atcagcaaat cgatatcaac tggcttttta ataaggtctt gctccagttc
    21061 tacgatatga cgtaatttat ccaaaaagaa taaatcaatc ttggttaagc cagctagctc
    21121 ttcaatacta tagccacgac gaagggcctc agaaagatag aatagacgat cgtcctgtgc
    21181 tcttacaatg tgagcaacca gctcatgatc actgatagta tctagaccct tcagttcgtt
    21241 atggtgtact ccaatttcca acgagcgaca agcctttaag agacattcct caatacggcg
    21301 tccaatagcc ataacctcac cagttgcttt catctgggtt cctagacgac gctccccccg
    21361 ctcaaacttg tcaaatggaa agcgtggcag cttggcaacc acataatcaa gagctggttc
    21421 aaacatggca taggtggttc ctgtgaccgg attaagcatg tcatcaagcc ttaagccaac
    21481 tgcaatttta gcagctattt tagcgattgg ataaccagtt gcctttgaag ccagtgctga
    21541 tgagcgagat acccgcggat taacctcaat cacataatag ctgaagctat tgggatcaag
    21601 tgccagctga acattacagc ctccttcaat cttaagggca cgaataattc tcaagctagc
    21661 atcacgaagc agctgattct caacatctga tagggtttgt gtcggggcaa aaacgattga
    21721 atctccagta tgtatcccta ctgggtcaaa attttccata ctgcaaacaa ccagcgcgtt
    21781 atcagcagca tcacgcatga cctcatattc aatctcttta aagccggcaa tggagcgttc
    21841 aatcagacac tgggtgacag gagatagctt caggccattc tccacaatat ctcgcaagac
    21901 ctcttcattg gagcaaatac cacctccagt gcctcccaga gtaaaggcgg ggcggacaat
    21961 aacagggtag ccaatggcat ttgcaaagcc gatagccgcc tctactgtcg tcacaatctc
    22021 tgattctgga ataggctctc ccaactcttt cattaattgc ttaaataaat cacgatcctc
    22081 tgcctgatca atagcagata aggttgttcc aagcagctcc actcctaatt cttgtaaaat
    22141 accagcctta gacagttcca tcgccatgtt aagaccggtc tgcccaccta aggtcggcag
    22201 caaggcgtct ggtctttcct ttcttaagat acgactaaca aatgccaacg tcaggggctc
    22261 gatataaacc ttatctgcaa cctctttgtc tgtcataatt gtcgcagggt tagaattaac
    22321 cagaacaacc tgatagccct cttcctttaa ggctaaacaa gcctgtgttc ctgcgtaatc
    22381 aaattcagct gcctgcccaa taacaatagg accagaccct atcaccatga tttttttaat
    22441 atctgtacgt tttgccataa tatctggtac aaaaggcctt aacaatccga ataaaataat
    22501 gcaagcacct aacattaaag catcacaatc tattttttac taggatttgt acctgtactc
    22561 agctgcagca agccctttgt acctactcct ttcattattt gccgtctcac agggcggcat
    22621 taaataaaac acttaacagt ctgtcacatg agacgatgag tacaagatca agtaaccctt
    22681 agctcagcaa gtatagatga cttaattgat atagtctttt tacttctaaa gagggcgatc
    22741 ttgccagcaa atactagtca taacccgcgg cagagcgatc atttcccact agtctatctg
    22801 ctgcctgact caagctgttt catgacagct gatcaagcct ttggtgcttg ctttttgatc
    22861 tgctagcaca cttgattaac atttgccttg ctgctctagc tgccaggcgt caatcatatc
    22921 taaaaattca tcaaatagat agctagcgtc atgagggcct ggtgcagcgt ctgggtgaaa
    22981 ctgcacagaa aaggcgggaa catgtcgatg tctcacccct tcaacagttt tgtcattaat
    23041 ctcctcgtgc gtaaccatca agcagtctgg caagctgtcg cgctcaacag cataaccatg
    23101 attttgacta gtaaaatcaa tacgtccggt cgctatttct ctgacagcat gattaaagcc
    23161 acgatgtcca aaaggcattt taaaggtctt agcgccatta gctaagctaa gcagctgatg
    23221 gcccatacaa atgccaaaaa ttggaatttt tccttgaaca ccacgaatca tctccaaggc
    23281 ctccggcaaa tcctctggat tacctggacc atttgatagc attagaccat ctgggttgag
    23341 ctgtagaatc tcttctgctg tgatatcaaa ggggactatt gtcatctgac attgcctttt
    23401 ggataattct cttaaaatgg aatgcttcaa gccaaagtcc accaaaacaa tatttttccc
    23461 aacacccgga gcgggatagg cagtcttagt tgacacctgc tcaataccat tagtcggaag
    23521 cacagttgca cgcagctgat cctttaggtg ttcaagcgta tcaccatcat ctgccattgt
    23581 tgccttcatc gtaccatgct gacgaatgat tttggtcaac gctctggtat caattcctga
    23641 aatgcctgga atccccttat gctttaaaaa ctcgtccaag gtcatttgct gacgccaatt
    23701 gctagctatc ctgcttactt cagagacaat gacccctttg caagttgggg caatggactc
    23761 ataatcatca cgattaatac cataattacc aacaagggga taggtaaata ctaagagctg
    23821 cccgttatag gactggtctg tgattgactc ctggtagcct gtcattcctg tattaaagac
    23881 aatctcgcca gtgacatcaa tatctgcacc aaagggcttt ccttcaaaaa tggtgccatc
    23941 ctctaagata agtaaccgtt ttgccatttt aaccccctct aacatgcctt tagaccttat
    24001 cgtttctgcc attaaggatc gcttcgataa tggccatacg gacaaataca ccattagcca
    24061 tttgagctac tattcttgcc tttggagcct ctactaaatg gtcagcaatc tcaacatcgc
    24121 gattaaccgg tgccgggtgc ataataatcg cagagtcctt taaccgcctg tagcgctcct
    24181 cagttagacc aaactgtcta tgataatctt ccttggaaaa gctttgacta ccatcatggc
    24241 gctcatgctg caccctaagc agcatcaaca catctaattg atcaataatg tgatcaatcg
    24301 ccatgtacct tccatagctg tcaaattcag acgagtacca ttgctcagga ccatagaaat
    24361 aaagctctgc tccaagccgc tttagaatct gcatgtttga tttagccaca cgagaatgtg
    24421 tcaaatcccc tgcaatagca atcttcaggc catcaaaatg accaaattct tcataaatag
    24481 ttagcaaatc aagcaagcat tgactagggt gctgacctga tccatcacct ccattaacga
    24541 tagaggcagt aatcgttgga ctgtcaataa gctgctgata gtaatcatct tctgggtgac
    24601 gaatcacgca gatttctgtt cctagagcac tcatggtaag aacagtatca tataaggttt
    24661 cccctttatt gacagcactt gtatcagcgt taaaatcaag gactctaaga ccaagcttgt
    24721 tctcagcaac ctcaaaggat ttatgggttc ttgttgaatt ttcaaagaat aaattagctg
    24781 caaagtgcct actgttatct ttaatagcta ccttacctgc cttgtattca gagccacgac
    24841 taataagtcc taaaacctct tcatttgtta aatgctccat tgacaccaaa tgcttaagcg
    24901 caacacgatt atttacaact gacatgattt atcccctttt accaataatg aaatgatgat
    24961 aacaattgac aacagctaca cactagtttt ctggaagaag ctgatacaat ataatgccaa
    25021 gaagcgttga aaaagcaaca cccgaaatct gaaggccatt gatttgaagc atgaggcctc
    25081 caataccaga aaccagaata acactagcaa tcaataggtt tttcttgttg tccatatcaa
    25141 ccttagcttc aatcaggatt ttcaagccac tagaggctat aaccccaaac agagcaatcg
    25201 aaatccctcc aatcactgga gtaggaatag actgaataag tgctgatacc ttaccaacaa
    25261 agcttaacaa accagcaatc acagcggcac ctgcaataac atagactgag aagattttat
    25321 tgagggccat cacaccaata ttttcaccat aagatgttac cggaggcgct cctaaaaatc
    25381 cagcaatcac ctgtgcaagg ccatcacccg tcaaggtttt ttccaagcca ggatccttga
    25441 aataatctct tttagtcagg ctattaagca ccatgatatg accgaaatgc tctgtcatgg
    25501 tgacaaaggc aatcggggcc atcgttaaaa tagcactagg atacaaggta atgtcatagg
    25561 ttaaaaaggg gatagccaca gctggaacac tgagccattg ggccttagca acctgtgtaa
    25621 agtcaacaat agactgaccc gtcaccatac caacaaggat cgcaaacaaa tagccaacca
    25681 ataagcccaa caaaatagga atgatggcga caatcccttt accataaatg ttaaagaaaa
    25741 taatcgctaa taaggtgaca agaccaatca aaaggtataa caggttatac tttccatcct
    25801 ttagcatgac atcactaact gctgttgagg ccaagctaag accgatcacc ataacaatgg
    25861 gaccaaccac aactggaggt aagatcttat cgatccattc attgccaatc gccttcacca
    25921 ccagtgctac aaccagataa accaggccac ctgtaatcgc tccctgtgca actgcaccaa
    25981 taccatctgt tttcattagc atttgcatgg ctgcaatata agcaaagctt gagcccatat
    26041 aagcgggaat tttaaatgtt gttactgaca aatgcgccag agtcccaagt ccacttgata
    26101 agagggcaac tgacggatca atcccaacca aaattggaac caaaacagtt gctccaaaca
    26161 tagcaaataa atgctggaag gacaagccaa gcaaaatccc tgcctttggc acttcttcta
    26221 catcataaat gacatctttc acacaatcac ctctttctta tcccggatca acaatactaa
    26281 tacgatcttg accgtcaacc tcaaccacct caacgacaat ctcttctgtc ttgcttgtgg
    26341 gaatattctt tccaacataa tcggcccgaa ttggtaattc acgatggcct cgatccacca
    26401 aaacagctag gctaacacgt ccaggacgcc ctaagctaac caaattgtcg atagctgccc
    26461 gaatcgttct gccggtataa agcacgtcat ctactaagat aatatccttg ccggtaatat
    26521 ctaccggcat gctggtggtg tcctcttcca ctctcatatc atctctaaag ggcttggtat
    26581 ctagctctcc aactgccaag tgcaggcttt ctagctgctc taatctttct tgaatacgac
    26641 gagcaaggta aacacctctt gttttaatcc ctacaagcac cacattgtct agttgcttgt
    26701 tgcgctcaat aatctcgtac gtaatccgcg tgatcgcacg cttcatggtt agctcatcaa
    26761 caattacctt tgatttcatt caaagcctcc tcaaaaaatt caactaaaaa aatctccctg
    26821 ttaacaagga gattcagcaa aacaggcaca cagctagaca taactgtgca cttttttatt
    26881 cagaacatgc tccttgccag cctcacagga ctgttttaaa ggaatatttt attttcatta
    26941 gtatagcaaa atcacaagcc aaaaacaagg attttctaaa aaataattca aaatatatag
    27001 agctatcaca gcaccaagga aaatgctact aaggtcatca gcaatcctcc aacacaattc
    27061 caaaaatagg tcttaagacc tattgtattt gtatcaaaac aatagtacaa taatatcaaa
    27121 cacaaaggag agcgtttatg atgaatgata taactagaaa gattaaccat aagcaactga
    27181 ttcaaatcac taccattcta ggcattattg ttaccatcgt tattttgttc tatctgcagc
    27241 agcaccctaa tctttttgca gttggcggtc cttttcagac ctatcttatg gaacttggta
    27301 tcctagcacc ctgtttgttt atactgcttc aaatcattca agtggtttac cctatcattc
    27361 ctggaggctt gacctgtgtt ttagggcatg tagtctttgg gccgttttgg ggatttcttt
    27421 ataatactct aggtattttt attggttcgc tgcttagctt tatgctcgct agaaaatatg
    27481 gtgaacagtt tgctaaagcc tttgtatcag atgataccta taacaaatac attccttacc
    27541 tcaataaagg caagtacttt gaacgatttc tcataacagc ctttattctc cctggctttc
    27601 cagatgattt tctctgtatg gtagctggac taagcagcat gtctatcaaa acatttacca
    27661 gtattttctt gatatcaaag ccaattactc tttatatcta cacccttctt gcttaccaag
    27721 gcatacaaat cgttggacag gtattgcaat cctaaaaaaa gctagtatta agctatcaag
    27781 cctgattgga atacagtatt ccaatcaaaa aggcgctcag cttggtacca gctttttatc
    27841 cttgtcttag ttgctccaaa gtcctttgga agatttctgg tggctcaaca gtaaagacca
    27901 gctcctctcc tgtcacaggg tgggttagtc ccaatgtttg cgcatgaaga aactgcccct
    27961 tgccagccaa ggtcttacga ggaccgtaga gtggatctcc tgcaagaggg tgaccaatat
    28021 aagccatatg aacgcgaatt tgatgcgttc gacctgtttc caattgtaat tccacgaagg
    28081 tatagtggcc aaagcgctcc aaaaccttaa aaagagtcaa ggcttccttg cccttagcag
    28141 ttacggtctg ttttttacga tccttttcac tgcggccaat cggagcttca attacacctc
    28201 gatcctttgg taaattacca tgaacaatgg ccacatactt tcgtaaggat ttcttagcct
    28261 tgagctcatc agctagtagc tggtgggcct tatcggtctt ggcaaccatt aaaagaccag
    28321 aggtatcctt atcaattcta tgcacaattc ctggacgaat aacaccatta atagaagaca
    28381 ggtctttgat atgatagagc aaggcattga ccagcgtccc tgtagaatgc cccgcagaag
    28441 ggtgaacaac cattccctga ggcttattaa taatggccaa tacatcatct tggtagacaa
    28501 tatctagtgg tatatcctga gcctgatagt ccaagctgct ttcctctggg atatgatagc
    28561 taatgcagtc acccacctgc acaatatact tggccttctt aggtaagcca ttgaccaata
    28621 cccttttttg cttgatctga tcattagcct gacttcttga taatggggtc aaatcagcca
    28681 aggccttatc caagcgatgg cctgattctg ttatcttaat ttccatagtc ctcttctttc
    28741 catagacaaa tgaccagcag caaaacacct atcgtcaaat aggaatctgc cacattaaaa
    28801 atagcaaaat tgatcacatc taaatgaatc atatcaacca cataggataa cctcaagcgg
    28861 tcaataaaat tcccaagacc tccagatata atcagcaata aagagagctg tagccaaaag
    28921 ctagcctttg ggtgcttcaa cacataataa atggcatagc caaccaccaa aacagttatg
    28981 attgtaaaga accactgctg attctgtagt atggaaaaag cagctcctcg attttgaaga
    29041 taggtcaagc tcaccaaacc tggtataaag ggcttcacct gccctagctc aatatgtgta
    29101 acagtccacc atttacttag ctgatccagt atcattaaga caatggcagc cataataaaa
    29161 ctaattcttt tcaactaatc ctattccttt cagcttaaaa acaagagatt accttgatgg
    29221 cttcaaaaaa gcaacaacag ccagctgtct ctgtagcgta ctcaacctta aagcctccaa
    29281 aaactggtat tctagtaacc ttttagtatc attgatagtc aaccacacag cagctctaga
    29341 cttgacttta tatcaacaag tctcaccaca gcagctcgct taatccttat ccataccaga
    29401 gctaagtccc attgtctata gcttgctttt cttttcgatg ttcaaaataa tcctgtaaaa
    29461 tggtcacaaa atgtaaagcc gcagcagata ggttcttatc cctacgcttg acataaatca
    29521 ttttatgctc catatgatca cgcaagggaa taaccttgat gccattaacg ctttgctgat
    29581 ctaaaaatcc agaccctgtt gcaaaggcag ctgtcctttc caaaatgcca tttaaggttg
    29641 ccctatctga cacagtgtat atgtgaggac tcttgcttgt gtcaataaaa ttttctgaat
    29701 aataaagata ttcttctttt tcttgagtaa agcgtaccgc tggcagccct tgcaaatcct
    29761 ctaagaaaag ggctttcctt tgagccaatg gatggttttt tgataggtaa atatgggttg
    29821 taaaggatag caattcaaca taatccaaag ccagcttatc cattcgctga aaaagcccct
    29881 gacggttttg tgcattaaga tagataattc caagctcact atttccctgt gccacctcat
    29941 ctaaaatttg catagtcgtt gactcaaaaa ctctaaaaac cttatgccca gcatgctttt
    30001 gggaaaatgc tgttattaaa gctggtaaaa aatcataatg ctgactcgca attgaaaatt
    30061 catttggctc caaagccgat tgagaaaact ccttttccag cgagtcaaag cacttaacaa
    30121 cctctaaggc cttttcataa aataaaagcc cctggctggt taacacagtt cctgctgttg
    30181 tcctacgaaa gatctgaaag ccaagctctg tctccaaatc cttcactgaa acagacaaac
    30241 tgggttgact gacaaatagc tttgaagcag cctcacgaaa ggtaccatta tttgcaatag
    30301 caaccacata tcgtaattgt tgaatattca ttaatccact tcctaaatct agtacccttc
    30361 attataccat aaagccagcc aatgaaaaat aaaggcgtcc atcttaacca tgccaaacgt
    30421 atctacagat aatcatgaga tagcattgac tttttcaata gtgtcttatc atatttagct
    30481 atagaaaaca gccttactat aagttatact tttgaaagaa gtaagcctta gatcacagaa
    30541 catcacactg agatttttta tgcgcttatc ctgtctgtcc aagaactgag aattggctac
    30601 atctagctaa taagccattt caggatttta ctgtctagga gttatttata ggcaactatt
    30661 acagtaagat agtgtcacaa tacaaaaaag gctatcccaa agtacagaac agccttatac
    30721 cgtgcccttt taacacatta ttttgcgatt gggtatacag aaacttgttt cttatcgcgt
    30781 cccttacgct caaagcgtac aacaccttca accttagcaa aaagagtatc atctccgcca
    30841 cgaccaacgt taacaccagg ataaatatgt gtgccgcgtt gacggtaaag gattgaacct
    30901 cctgaaactg tttgtccatc agctgcctta gcgccaagac gttttgcttg tgaatcacgt
    30961 ccgttagaag ttgaacctcc accttttttg tgggcgaagt gttgtaggtt agaaagatta
    31021 agtttaatca tttttatttc ctctcgttga atttaattca tcacaggctt ttgaacatat
    31081 tctgataaat gctctgccaa attctccaag ccaatcacaa cagactcaaa cagaatttgc
    31141 cacacctgct cttgttgctc agtaaatccc tcaggctttg ttacccttag gaatccacca
    31201 ccatcgacca tttctagtgc tggctcaaga cctgtcatct gttcaactga attaacaaga
    31261 ttgaaggcca aaactgaaac cgaagcacaa actacatcaa agccgtactc accgcttcca
    31321 gcatgtcctg tgataagcat ctcagtccag ccagctgcgt cttttgttaa ccgtacttta
    31381 atcatgtcaa actagaatta tgccttgata gcgttaatca caactttagt gtaaggctga
    31441 cgatgacctt gcttacggtg gctacctttt ttaggcttgt acttaaaggt tacaaccttc
    31501 ttttgttttc cttgcttttc aacagttcca acgacagtag ctccctcaac aactggagta
    31561 ccaacgacag tcttatcacc acctacgaga acaacctcgt taaaagtgat ttctgcgcca
    31621 gcttcagcgt caattttctc aacgtagatt gcttgaccta cttcaacttt aacctgtttt
    31681 ccaccagttt tgatgattgc atatgtgctc atgatgcacc tcctataaga tttttgatga
    31741 ggtttccctc tgtgaagact cgcctagaat cgtgagagcc aatctacttg aaaacgattt
    31801 tcgtgcggtt gcacaggacg tgcacttagt caacgttaca attttaacat caaatttgat
    31861 ttttatcaag aaaaatatgc ttttatcttc ctaaaatctt aagctataca taatcacagc
    31921 tatgtaaagg ctagcaatgc tttaccattt taggttaacc agggcattca tttctttata
    31981 agcaatagct gctttttctt gcgtttcggg atcaatctta tcataatatc tgccgccttt
    32041 gataaagtcc tccaaaacca tggtacgata gctatatagc tcatagcctt cactaccata
    32101 aaggccctta ggcttagcta aaaccattgt cgggtgagcc tttactgttt ttatttttgt
    32161 tttttgcccc ttcttctcaa aggtaaggtc cattagcacg ccgcgctctg tccaaatatc
    32221 atcaacagtc tctaggcgtt gattggaaat gaaattaccc attgaataga taataaattt
    32281 cttttccttg tccttaacaa tcgtctctgc cggctctacg acgtgggggt gacctcctaa
    32341 gacaacatca gcaccccagt caatcatttt tcgataaaga gttttttgct cagctgttgg
    32401 ctctaaagca tactctgtgc ccatctgcgg cataacaatg gtaatatcgg cctctttttc
    32461 agcacgcaag atgtcttttt gtatcttttc ctcattaagg tcagacaggt gcttgtcata
    32521 ctcctcctga ctgagtgtcg cctccattcc attatagcca tatgaatagc ccaatattgc
    32581 aatcttaatc ccattaacct ttttaatgag aatgttctcc ttagagcgat cctgctcata
    32641 aataccaatg ctgtctatcc ccatatcagc aaaaacacgc ttggtattga gagctccttc
    32701 taatcttgag tccaaaatat ggttatgggc caaatcaacc acatcatagc cagtatgctt
    32761 aagcgcagca gcaatagcct ctggcgcatt aaacaaagga tagccagcta gaggatagtc
    32821 tggactgatc gttccctcat agtctccaat ggccaaatca gcctgactaa tccaatcctt
    32881 cacatactca aaatagggat taaaatcata gctaccatca gcctttttag cactcatata
    32941 gagaatatca tgaatcaaaa tatcaccatt tgcgacaaca cgcgctgttt gtgtcttttg
    33001 aggtgtcttg cttttcgttt gtgtgccttt ttttgacatg cctaataaat caaaggccaa
    33061 cccaaaaaca agtatcacca caatcaaggt aagcactgaa agcatggtct ttttatactg
    33121 aaaatctttt agcaagcgtc aaacctcctt ttttcctatt ataccatgtt gacacgactt
    33181 tttaataaca aatcccaaag aaaaggctat gcccatttaa gaagaatgcc ttagacagca
    33241 gcatagactc gtattagcta gtcaaaaaac tagattgctc ctctttggtt gatgtcatat
    33301 actttgagcc taaatagctt tcaacaaagt ctaatagttg aataatgtca tgcaaaatat
    33361 ggtataatga aacaaaatca aactagtcag gatagtcaca tgaagcataa ctctttcagc
    33421 cgctcactat tactccccct tctcatctgt tccttgtctg cttgctcttc tcatacagag
    33481 aaaaaagacc ataccaaaga cgctactgct atcaccgata cccgaaaagc agagcatcag
    33541 gacatcaggg caaatatgga aaaggtcaag ctcgctaccg ctagcaccga cttcaaaggt
    33601 ggctcaagcc ttgaggagct aatcactatt tttggacagc ctagtcagca cgaagaaaaa
    33661 gcagctggta gtgttactct tgactcctac acatggcagt ttgaccatgt cacggttaat
    33721 attaacctct atgaaaacag cagcattgtt aaaactattg ctaactttgc ttttattaga
    33781 gacctgacct tatccttaaa ggactacaac agcttgaaaa agggcatgac ctatgatgag
    33841 gtcaagcagc tattgactga gcctgataat tacagtcaag ccaattccag tgaaaaagaa
    33901 accattcaag ccatttggat tagtggctta aaagctcaga cacagggtgc caatatagca
    33961 ctaacctttg aaaacaacca gttgacagaa atgtcacagg ttggtcttga agactagttt
    34021 gtggataacc ccaatcatat taatgataga aaaaagcttg atatttaata agatcaagct
    34081 caaacgatag accaagtagc tgatgatctt gacagtaatg tgtaacaagc tgagatacta
    34141 ctcactaggc agtatttact agcagccact gaatttcctt tatgatgaca ggcaaccacc
    34201 ttttttgtgg tgacctatca atagcaccat aagctctctt ttgtcacata ccttgcttaa
    34261 cattatttta ccaggtatgt gatgagcttt ttaggttgtc tgatagtata acatctaacc
    34321 cctagttgat gatgtagata aggcaagagc tgctaaggat agcaccataa ataagatcca
    34381 acatagggtc atattatata gtgccaagaa cgaaaagata aagacaccta cagggagcga
    34441 taaagagaac agaagaccta aaaagttatt gctttgggct agcatatctg atgggagatt
    34501 ttccattaaa agggcgtcca gcttgggtgt ggcttttccc ataatataag ctgcaaaggc
    34561 taagcataaa acccctatga tggcaggtaa ttgcagagca ttagagactc ctaccagcaa
    34621 aaatgctatg ccctgagtct gtactagctt tgatattgaa agccttgaaa agtaatcctt
    34681 tggtgttaga tttcccaaca tcgctccgat aatcgtaacg gcatcaacaa taactaaaga
    34741 ctgcccataa tgaaaatgaa atagctgatg atccatcaaa taaaaatgat aaatgctatt
    34801 aattgctcct ccaatagcgt ttaaggtcaa gatggataag agtaacatca caaaagagat
    34861 atgatcaatc tttttaaagg tctctgtcat ccttgtatac atcaccttaa attgcttcat
    34921 taatgaaaca cctgcttcag aagcttcaac gacatcatgc cttagctttt gtcgattttt
    34981 aagaagcaca acagatgaca ataaaaagga aatagcattt atcaaagcaa caaaggcata
    35041 attgttgcct gatgtcgtta gcagccaaac tcctaaagct tgtcctgcaa tactagagag
    35101 gtagccgata aattgagcaa aagaataggc ctcatagagc ttttctgatt caatattttt
    35161 ctgcattatc gggagacgta agccattttt gtaatcactt agaatatcag aaaccacatt
    35221 caaaaagccc acaaaggcaa ataccaagaa cgtctgattt gtcatcaaca aggctacaag
    35281 cgtaaataaa agagattgta taaaaccaat aacaataaga tttcttgttt tcctttttgt
    35341 cttatctgct ttgacgccaa tccaaaaggt aaacaccata ggaatgatgg tgatgatatt
    35401 ggctataaaa acagcaatat gagaataagg tagcgtggtt gcataaataa taaaaacaat
    35461 attgtaaata taagagccta aagcacttaa aaagtttgaa actgtcagtg ttctaaaaac
    35521 gacattttta atcaatcccc tcatttactt acctgttgac gtcctttctt atgtcacctt
    35581 actttacttg attgaatata cttacagcat atctaaattc gtactgtagt tttatatggt
    35641 gttctgacat gattttgcta ctaattagta attcacaagc cttttctaag tataaagtat
    35701 cgtttgttag tctaaatact tgtaaaagtg tcatggctat ccccagcatt ccgttccata
    35761 gaccactaaa ctgagcaaat tcaactaata acgactccga taaattctta atatctttaa
    35821 tatatttatc ggagttaacg taaataagca attgaacgat cccagcagtc ccatttgata
    35881 agtatggaga tacagaattt tctgatatta atacaccccg atttccatcg ctatcttcaa
    35941 ctaagctttc tagaataaaa tcaattcctt tctcaataat ttcgttatca taagaaattg
    36001 aagacagata gaacaatact ccagctaaac catttaaccc taaattaact tctgatttta
    36061 attgcatcaa aacttcatcg gatttatcca aaatcttatt atatttagta attagtgtgt
    36121 cttgtaaaga aataatatta acaagttct
//
LOCUS       DARYUW010000018        32222 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYUW010000018 DARYUW010000000
VERSION     DARYUW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32222
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            82..155
                     /locus_tag="TVW11_000763"
     tRNA            82..155
                     /locus_tag="TVW11_000763"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:116..118,aa:Met,seq:cat)
     gene            180..252
                     /locus_tag="TVW11_000764"
     tRNA            180..252
                     /locus_tag="TVW11_000764"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:213..215,aa:Phe,seq:gaa)
     gene            258..328
                     /locus_tag="TVW11_000765"
     tRNA            258..328
                     /locus_tag="TVW11_000765"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:290..292,aa:Gly,seq:tcc)
     gene            358..431
                     /locus_tag="TVW11_000766"
     tRNA            358..431
                     /locus_tag="TVW11_000766"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Ile,seq:gat)
     gene            441..528
                     /locus_tag="TVW11_000767"
     tRNA            441..528
                     /locus_tag="TVW11_000767"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:475..477,aa:Ser,seq:gct)
     gene            587..1402
                     /locus_tag="TVW11_000768"
     CDS             587..1402
                     /locus_tag="TVW11_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1364886.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            1405..1908
                     /gene="mreD"
                     /locus_tag="TVW11_000769"
     CDS             1405..1908
                     /gene="mreD"
                     /locus_tag="TVW11_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1364887.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2004..3182
                     /locus_tag="TVW11_000770"
     CDS             2004..3182
                     /locus_tag="TVW11_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1364888.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            3287..4249
                     /locus_tag="TVW11_000771"
     CDS             3287..4249
                     /locus_tag="TVW11_000771"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1364889.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4609..5379
                     /gene="recO"
                     /locus_tag="TVW11_000772"
     CDS             4609..5379
                     /gene="recO"
                     /locus_tag="TVW11_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1364890.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5495..6502
                     /gene="plsX"
                     /locus_tag="TVW11_000773"
     CDS             5495..6502
                     /gene="plsX"
                     /locus_tag="TVW11_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1364891.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6495..6743
                     /locus_tag="TVW11_000774"
     CDS             6495..6743
                     /locus_tag="TVW11_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1364892.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            6893..7603
                     /locus_tag="TVW11_000775"
     CDS             6893..7603
                     /locus_tag="TVW11_000775"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1364893.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            7782..11522
                     /locus_tag="TVW11_000776"
     CDS             7782..11522
                     /locus_tag="TVW11_000776"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1364894.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            11641..13098
                     /locus_tag="TVW11_000777"
     CDS             11641..13098
                     /locus_tag="TVW11_000777"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1364895.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            13155..14177
                     /locus_tag="TVW11_000778"
     CDS             13155..14177
                     /locus_tag="TVW11_000778"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1364896.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            14174..14731
                     /gene="purN"
                     /locus_tag="TVW11_000779"
     CDS             14174..14731
                     /gene="purN"
                     /locus_tag="TVW11_000779"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1364897.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            14878..16425
                     /gene="purH"
                     /locus_tag="TVW11_000780"
     CDS             14878..16425
                     /gene="purH"
                     /locus_tag="TVW11_000780"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1364898.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(16803..17957)
                     /locus_tag="TVW11_000781"
     CDS             complement(16803..17957)
                     /locus_tag="TVW11_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1364899.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            18348..19610
                     /gene="purD"
                     /locus_tag="TVW11_000782"
     CDS             18348..19610
                     /gene="purD"
                     /locus_tag="TVW11_000782"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1364900.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            19839..20327
                     /gene="purE"
                     /locus_tag="TVW11_000783"
     CDS             19839..20327
                     /gene="purE"
                     /locus_tag="TVW11_000783"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1364901.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            20314..21387
                     /gene="purK"
                     /locus_tag="TVW11_000784"
     CDS             20314..21387
                     /gene="purK"
                     /locus_tag="TVW11_000784"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1364902.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            21402..21626
                     /locus_tag="TVW11_000785"
     CDS             21402..21626
                     /locus_tag="TVW11_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1364903.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            22223..23515
                     /gene="purB"
                     /locus_tag="TVW11_000786"
     CDS             22223..23515
                     /gene="purB"
                     /locus_tag="TVW11_000786"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1364904.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            23813..24726
                     /locus_tag="TVW11_000787"
                     /pseudo
     CDS             23813..24726
                     /locus_tag="TVW11_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            24809..24907
                     /locus_tag="TVW11_000788"
     CDS             24809..24907
                     /locus_tag="TVW11_000788"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1364905.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            24941..25948
                     /gene="ruvB"
                     /locus_tag="TVW11_000789"
     CDS             24941..25948
                     /gene="ruvB"
                     /locus_tag="TVW11_000789"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1364906.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            26189..26647
                     /locus_tag="TVW11_000790"
     CDS             26189..26647
                     /locus_tag="TVW11_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1364907.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            26653..27054
                     /locus_tag="TVW11_000791"
     CDS             26653..27054
                     /locus_tag="TVW11_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364908.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            27051..28832
                     /locus_tag="TVW11_000792"
     CDS             27051..28832
                     /locus_tag="TVW11_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1364909.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            29253..31895
                     /gene="adhE"
                     /locus_tag="TVW11_000793"
                     /gene_synonym="adhC"
     CDS             29253..31895
                     /gene="adhE"
                     /locus_tag="TVW11_000793"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1364910.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
BASE COUNT         9115 a         5828 c         7602 g         9677 t
ORIGIN      
        1 ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaacag cgtgcgtggg ttcgaatccc
       61 acatcctcct ttaaagatta tcgcgggatg gagcagttag gtagctcgtc gggctcataa
      121 cccgaaggtc gtaggttcaa atcctgctcc cgcaattata taaaagatat atgctggttg
      181 gctcggtagc tcagttggta gagcaatgga ttgaagctcc atgtgtcggc ggttcgattc
      241 cgtctcgcgc cattttagcg ggtgtagttt agtggtaaaa ctacagcctt ccaagctgtt
      301 gtcgcgagtt cgattctcgt cacccgcttt atagttttcc caagctatag tgtgcttggg
      361 cgcgtagctc aggtggttag agcgcacgcc tgataagcgt gaggtcggtg gttcgagtcc
      421 actcgtgccc atcattattt ggagaattac tcaagaggct gaagaggacg gtttgctaaa
      481 tcgttaggtc gggtaactgg cgcaagggtt cgaatccctt attctccgta ttgtaaaggt
      541 gattatcata ctgataatcg tttttttatt tttagaggtg attttattga aaaagcttaa
      601 cctatctcgt ctcttttttt ggttaacatc attagcttta ctggctttga ccttggttct
      661 tctttttaga gtagctattt ctccatattt atcaatgatt atccgaaatc ccgttacaaa
      721 aattgatgct ataatgtcta agccttttgc tgttataaag gagggtgcaa aggaattaga
      781 tagcttgatg tctgcttttt ctgaaaataa gcatttaaaa aaggaactta ggtcctataa
      841 attggatcag ttacaggttg acaagctaaa atctgaaaat cgagagctca aggaactgtt
      901 agggttggat tatggtactg ataatcaatt tgctgccaga atgatatcaa gaaatcctta
      961 tagctggaat aaatcgctgg tcattgatag cggcaaaagg gaaattaagg agaagtcttt
     1021 ggttacttca gagcttggac ttattggtcg tgttacagct gttagccagt catctgctca
     1081 tgttgaattg ttaacatctg ggaagaatat tgagttgccg attaaaattg tagataagga
     1141 taaggtgatt tatggcaatt taaaggcatt taaatcagaa agtaaaacaa tggttgccag
     1201 cgaatttaat tctaatgact caatatcatt agatgctaag gtttatacaa gtggattaga
     1261 tggtgagact gtggcagata ttcctgttgg aaaggttacg ggctttaaaa atgctgctga
     1321 taagctaaag cgtcgtattt ttataaaatt gtatgctgat actgataatc ttgactatgt
     1381 tcttgttgtt ggaaaagagt gaatatgaaa aaatcttcag agctattagt ccttttgcct
     1441 tttcttttat tttttgttga tgcacacgtg tcagacctga tcagctcaat gttacctgag
     1501 ggttactcgg tagtatcaca cctcttttta ctgtttttcc tgatccttat ggtagcgttt
     1561 agatctaagg gagttatttg tttcttctct cttcttttag gattattgtt tgattattat
     1621 tattttgatc atatagggat tttgtctctt gccttgcctt ttggaacaat gatcgttcta
     1681 gggctattaa ggttcttttc tggttccatt agtcagctac aatttttcct tttctttact
     1741 ctttatatgt ttcttgtaga tgtatcaagc tttattttgg caaacagcta tcagttaact
     1801 gatatgactt ttccttatgt aatgacgttt cagcttgctc cgactttaat cgtcaatctc
     1861 cttattttgt tttgctttag aaaattaata ttaagtcaat tttattgatt attacataca
     1921 actgtaacag atgcgtaaca ttaaacgctt gattttttga tagaatataa tgtgtcttat
     1981 cgaaaaggag taattttttt agtatgaaaa aaagaattct atcagcggtt cttgtaagcg
     2041 gtgtgaccct tggaacagca actacagtgg gagcggatga tttagattcc aaaatagcgt
     2101 tgcaaaattc agttatttct aatttaaata aagaacaaaa agctgcgcag gatagaatga
     2161 agactttgca aagtcaggtt agctcattac aatctgaaca agaaaggtta gtcgctaaaa
     2221 atggtgagct tgaagcgcga tctgctcagt ttgagcagga gattcaagtg cttgccagtc
     2281 aaattattgc tcgtaatgaa aagttaaaag gacaggctcg tagtgctcaa aagggaaata
     2341 cgttaggtta cctcaatgca cttttgaatt ctaagtcaat ttctgacgtt attactcgtt
     2401 tggttgctat taatagagct gtgtcagcca atgcacagat gttggaaaag caaaaggctg
     2461 ataagctttc tcttgaagaa aagcaacagg aaaatcaaga agcgattaat acaattgctt
     2521 caaatattac agcaattgaa tcaaaccaag tagctttaaa gactcaacaa gcagatttag
     2581 aggttgccaa ggtagatttg gcgcttcaat tagcaactgc tgaggacgag aaggctagct
     2641 tgattacccg taaagaggct gcagagcagg cagcagctca agccaaggct caggcagagc
     2701 aggaagcagc agccagagca gcacaggctc aagctcaagc acagtctgta gcggcagctc
     2761 aagcagcagt gactcaagcc gtaccaacac cagctccagc gcaggcacag cctgttgtgg
     2821 cgccagcagc tatggtttca acaccagcgg tgtcgtatgc ctatgatcct tctaatccgt
     2881 accctgtcgg ccaatgtact tggggagtta aggctttagc tccttgggtt ggcaattatt
     2941 ggggaaatgg tggtcaatgg gcatcaagtg cagcggcagc aggtttccgt gtaggtgcaa
     3001 caccaatggt tggctctgtt gttgtatgga atgatggtgg ctatggtcac gttgcctacg
     3061 taacaggtgt tcagggtgga cagattcaag ttatggaagc caactatgct ggaaatcaat
     3121 ctattggcaa ttatcgtggt tggtttagcc caggtgctgt atcgtatatt tatccaaatt
     3181 agaaaataag taaaggtaag aatcaggatt cttacctttt tatttccatt gaaaaattga
     3241 ttgaaaaggg ttaaaatggt ataggatcaa aactttggag gaaaaaatgt cttattctga
     3301 tttaaagctg tttgcattat cgtcaaacaa ggaattagca gaaaaagttg ctgctgcgat
     3361 gggaattcaa cttgggaagt ctacggttcg ccagttttca gatggtgaga ttcaggtcaa
     3421 tattgaggaa tcaatacgtg gacaccatgt ttttattttg cagtcaacaa gctcgcctgt
     3481 taatgataac ctaatggaaa ttttaattat ggttgatgct ttaaagcgtg ccagtgctga
     3541 gaaaatttct gtggtaatgc cttattatgg ctatgctcgt caggatcgta aggctcgttc
     3601 gcgtgagcct attacctcta aattagtcgc taatatgcta gaggtggcag gtgttgatcg
     3661 tttattgact gttgatttac atgctgcgca gattcaaggc ttctttgata ttcctgttga
     3721 tcatctcatg ggagcacctt taattgctga ttattttgat cgtcatggtc tagtaggtga
     3781 tgacgttgtt gttgttagcc cagatcatgg tggtgtgacg cgtgctcgta agctggcaca
     3841 attcctccaa acgccaattg ctattattga taagcgtcgt agtgttgata aaatgaatac
     3901 cagtgaggtg atgaatatca ttggtagtgt tgaaggtaaa aaatgtattc tgattgatga
     3961 tatgattgat actgctggta ccatctgtca tgccgctgat gcgcttgctg aagcaggagc
     4021 aacagcagtt tacgcatcat gtactcaccc agtgctgtca ggaccagctc ttgataatat
     4081 tcaaaaatca gcgattgaaa aattgattgt tttggatacg atctatttac cagaagaaag
     4141 actgattgat aagattgaac aaatctctat tgcagatttg attgcggaag ctatcattcg
     4201 tatccatgaa aaacgtccat tgtcacccct atttgaatta gggaaatgat aaggttagcc
     4261 tgaggtagta agccttaggc ttttttatgt tttaaaaggc tatttgatta ccaaagcagt
     4321 gtttgattta acgccataga taggcttcac tgtcttatgg taggtgttga gctattatag
     4381 caaaaagtca tgtgtaggtg ctgtgtttaa acagctagcc tatgattcat atagttatgg
     4441 ctagtgactg ttgagcttct tattctcaga gttgttacga gccttaagta cagtgttagt
     4501 catgcaattt tcctggattt tgggtataat atagctgtat ttaaggtgtt ttaaaggtct
     4561 agtaagaaag gcattattac tagctgagaa gcttggttat ggagatatat gcgtattcag
     4621 aggtcacttg gtattgtctt gtacaataaa aactatcgtg aagatgataa gctcgtaaaa
     4681 atatttacag aagcggcggg caagcgtatg tttttcgtga aacatattgg tcgttctaaa
     4741 ctagctcctg tggtccagcc tttaacggct gctgattttc tattgaaaat caatgattcg
     4801 agcctttctt atatagagga ttataatcag gtggaggctt atcggcacat caatgaagat
     4861 ttttttaggc tatcctatgc tagttatgtc ttggctctgg ctgatgcggc tattccagat
     4921 aatgagcctg atcctcagtt gtttgctttt ttgaaaaaga ctcttgatct gatggaagaa
     4981 gggctagatt atgacatttt aacgaatatc tttgaagtcc agattttgga tcgttttggg
     5041 gtgagaatga attttcatga ttgtgttttt tgtcacagaa ccaatctgcc ttttgatttt
     5101 tctcataagt attcaggtgt cctttgtccg cagcattacc atgaggatga gaggcgatat
     5161 ggcttggatc ccaatgtgat ttatttgctt aatcgttttc aaacgcttaa tattgatgag
     5221 ctaaagacta tttctgtgaa tactggtatg aaaaaaaagc ttcgtctttt tattgatgcc
     5281 ttgtatgagg attatgtcgg tattcgtcta aaaagtaagg tttttattga tgatttggct
     5341 aagtggggag atattatgaa aaacaagcag ggcttgtgag ctattcaggt gtggatttgt
     5401 ccttttatgg gaattgtctg gggaatatgc tataatagtt acgttattct ctaggatatt
     5461 tttcgttaag aaaaatagga ttaaaggagc aaaaatgaag aaaattgcaa tagacgctat
     5521 gggtggtgat tatgccccta aagctattgt tgagggtgtt aatcaggcga tagaatcctt
     5581 ttcagatatt gaaattcagc tttatggcga tcaatcaagg attgagtctt acctagttaa
     5641 atcagatcgt gtgtccattg ttcatacaga tgaaaaaatt aattctgatg atgagccagc
     5701 aaaggctatt cgtcgtaaga agaatgcttc tatggtttta gctgcaaggg cagttaagga
     5761 tggtcgggct gatgcagttc tttcggcagg taatacaggc gccttgttag ctgctggttt
     5821 gtttattatt ggtcgtatca agggagtgga tcgtcctggt ttgctgtcaa ctctgccaac
     5881 ggttgatggt tcaggctttg acatgttaga tttgggtgcc aatgctgaaa acacagcaga
     5941 gcatttacac caatatgcta ttttaggctc tttttatgca aaacatgtgc gtggtattgc
     6001 caagcctcgg attggcttgc ttaataatgg tactgaggca actaagggtg attctcttcg
     6061 caaggaggtc tataattttt tagcttcaga cagcagccta cagtttattg ggaatgttga
     6121 ggcaagagat ttgatgtctg gcgtggcaga tgttgtggta gcagatggct ttacaggaaa
     6181 tgctgttttg aagtcgattg aaggcactgc tatgagtatt atgggacaat tgaaatcagc
     6241 tatagcagta ggtggtgtta aggcaaagtt tggagctctt ttattgaaga gtagccttta
     6301 tgacttaaag gatactttag attattccag tgcgggtggg gctgtattgt ttggtcttaa
     6361 agcacctctt gtgaaatcac atggttctag tgatgccaag gctatttttc ataccattaa
     6421 gcaggttcgt acgatgctag aaacagatgt agttggccaa ttagttgagg agttttctaa
     6481 ggagagtgat gtaaatgact gaggaagtta ttttagagaa aatcatcgca ttaatcaaga
     6541 agcaaagaag tcgtatagac tttgacatta cagaaaaaac agcactaaag gatgatttag
     6601 gagtagattc gattgaactg gtagagtttg ttattaatat cgaagatgaa tttggtattg
     6661 atattcctga tgaagatgtt gatggcatgg tatctatggg agatatgcta aattatttgg
     6721 tcaagcgttt aaaccaaagc taaatagttt taaaagagca ccagctcttt ttttgtttcc
     6781 gaaaaaacga acattataag tttattttat attaaatgta aataaatgtt gaatatttag
     6841 tatgtttgtg gtattgttta gatattaaat gcaaagaaag gcgaacaaat aagtgtctaa
     6901 tcaactcatt tattcaggta aggcaaagga tatctatgaa acagccgatg acgggattgt
     6961 cttaatctcc tacaaggatc aggtcactat gctaaatgga gcacataagg aaatgattga
     7021 aggaaaaggg agccttaata atcagatttc tgccttaatc tttgataggc taaatagggt
     7081 tggcgtatca actcatttta ttaagcaatt atccgagaca gaacagttaa ataaaagggt
     7141 tgcgattatt cctttggagg ttgttttacg aaacgtggcc gctggctcat tttcaaagcg
     7201 ctttggtgtt aaagaaggtc aggctttgga cgagccaatt attgagcttt attacaagaa
     7261 tgacgcttta gatgatcctt tcattaatga tgagcatgtc agctttttaa agcttgcgac
     7321 tgatgagcag atagcctaca tcaaacaaga gacgcatcgt attaatgctt atttgaagga
     7381 gtggtttgct agtgttgggt tgacactggt tgattttaag ctagaatttg gctttgataa
     7441 ggaggggatg cttatccttg ctgatgagtt ttctccggat aattgccgct tgtgggataa
     7501 tgcgggccgt cacatggata aggacgtttt tcgtcgtcag cttggcagtt tgacgcaagc
     7561 ctatgagact gttttagaaa ggctaagagc attggatcaa taaagaccag cttatttgtt
     7621 gtcagttaag aaagggagct cttttttgtc cgtcatgtaa gaaaataaat cagttcagac
     7681 tatttgagct gctgtctaag aaaggctgtc tgctattgga gaaaagagtc aggctagttc
     7741 ttattttggg ctggtttctg attggacttg gtatattaac tatgaataaa cgtatttttg
     7801 ttgaaaagaa ggctgatttt cagattaagg cacaggtcct gttaaaggaa ttgaaacatc
     7861 agctgcagtt aaagacactg gttgatttgc gtattgtgca ggtttatgat gtgtttcatt
     7921 tggatcagga gctgctttta acagctataa agcatgtttt ctctgagcag gtcactgatc
     7981 aggtattgtc agaagaagct ttacaagcag atttaaaaag gtatgccttt tttgcgattg
     8041 aagctctgcc tggacagttt gatcagcgtg cggcaagctc tcaggaagcc ttattgttgt
     8101 taggagcctc aactgatgtg actgttttga cctcacagct ttatttggtc aatcaagaca
     8161 ttgctgctga agaattagaa gccttaaagc agtacttgtt aaatccagtg gattctaggt
     8221 ttaaggacat attagccggt cttgatgatc aggatttttc agtagcagat aaagtgattc
     8281 caacgcttga tgtttttaat gattatacag cggaagatct tgctcgttac aggtctgagc
     8341 agggcctagc aatggaagtg gaggatctgc tgtttattca ggattatttc aagacaaagg
     8401 ggcgagtgcc aacagagact gaactaaggg ttttggatac gtattggtct gatcattgtc
     8461 gtcacacaac ctttgaaaca gagctaaaaa cgcttgattt ttcagcttct cattttgaaa
     8521 agcagctcca agctacctat gagacctacc ttgctatgcg tgatgagcta ggtcgatctg
     8581 aaaggcctca aacgcttatg gatatggcta ccatttttgg acgttatgaa agagctaatg
     8641 gtcgtttaga ggatttggag gtttcagatg aaatcaatgc ttactcagtg gaaattgagg
     8701 tagatgttga tggtgtcaag gagccttggc tgctcatgtt taaaaatgaa acacataatc
     8761 acccaacgga aattgaaccc tttgggggtg ctgcaacctg tattggtgga gctattcgtg
     8821 atcctctgtc aggccgttcc tatgtttatc aagccatgcg gctttctggt gcaggggaca
     8881 ttacaagccc gctgtcagag actcgtaagg gcaaattacc acagcaggtt atttcgaggc
     8941 aagcagcaca tggttactcg tcatatggca atcaaattgg gctagcgact acttatgttc
     9001 gtgagtattt tcacccaggc tttgttgcca aacgtatgga gcttggtgcg gtagttggtg
     9061 ctgcacccaa ggaaaatgtg gttcgtgaaa agccaaggac aggtgacgtg gtggttttgc
     9121 ttggtgggaa aacaggacgt gatggtattg gtggtgcgac aggatcatct aaggttcaga
     9181 cagttgagtc tgtagaaaca gctggtgcag aggtccaaaa aggaaatgcc attgaggagc
     9241 gtaaaatcca acgtcttttt cgtcgtggcg atgtgacacg cctcatcaag aagtcaaatg
     9301 attttggtgc tggtggtgtt tgtgtagcca ttggcgagct tgctgctggt cttaacatta
     9361 acttagataa gattccttta aaatatgctg ggctaaatgg aacagaaatt gccatttcag
     9421 aatcccaaga gcgtatggct gtcgtgattt gtccaaagga tttagaggcc tttatgagcg
     9481 cctgccataa ggaaaatatc catgctgctg ttgtggcagc tgtgacagaa aaaccgaatc
     9541 ttgttatgac ctggaatggg cagacgattg ttgatattga acgctcattt ttagagacaa
     9601 atggtgtgcg cgtgtctgtt gctgctaagg ttgttgacag tggtgcgcca ataccagaag
     9661 ctcgtcaaac tactgctgag acacttgaag cagataccat tgctgtctta tcagacctga
     9721 accatgctag tcaaaagggt ttgcaaaccc tgtttgatag ctcagtgggt cgctctacag
     9781 taatacatcc gcttggtggg cgctatcaaa tgacacctgt tgaaggctct gttcagaaat
     9841 taccagttca acatggagtg acaaagacag tctctgttat cgctcaaggc tatcaccctt
     9901 atatagccga atggtcacct tatcatggtg ctgcttatgc tgtaattgag gcaactgctc
     9961 gtctggtcgc aacgggtagc cattggcata aggcacgctt ttcatatcag gaatatttcc
    10021 aaagaatgga taagcaggca gagcgctttg gtcaaccggt ggcagccttg cttggagcaa
    10081 ttgaagcaca ggtgcagctt ggcttgcctt ctattggagg taaggattca atgtctggta
    10141 gctttgagga attgacagtg ccgccgacct tggttgcctt tggtgtgacg actgctcatg
    10201 tagatcatat cctttcacca gaatttaaag ctgctggcga gaatatttac tatattccag
    10261 gacaggctat ttcggaagtg attgattttg agttgataaa atctaatttt atgacttttg
    10321 aggctattca gaaaaagcat aatattagct cagcttcggc tgttaaatat ggtggtgttg
    10381 ttgaagcact ggctcttgct gcctttggta atcggttagg ggcttgtgtg acattaccag
    10441 agcttgacag gagcttaaca gctcagcttg gtggctttat ctttacatca aaagaggaaa
    10501 tcacaggtgt tatcaagctt ggtcaaacta ccagtgactt tacattggtt gtcaatgatg
    10561 tcaagctatc tggagctcgt ctcttaaagg cttttgaagg gagcctggag caggtttacc
    10621 cgacggtatt tcagcaggca ggtgaattga agcctgttcc tgtagtgaca acagcacttg
    10681 ctgctcagtt taaggaaaaa atagctcagc cagttgtcta tattccagtt tttccaggaa
    10741 ctaactcaga atatgattcg gctaaggcct ttgaaagaga gggtgcaagg gtgaacttgg
    10801 tgccttttgt taccttgaat gaggcagcta ttgacgcttc agttgacacg atggttgacc
    10861 atattcatca agctcatatt atcttccttg caggtggttt ttcagcggca gatgagccag
    10921 atggttcagc taaatttatt gttaatatcc tgctgaatga gaaggttcga atggcgattg
    10981 atgcctttat tgaaaagggt ggtctgatta tcggtatttg taatggcttt caagctctgg
    11041 tcaaatcagg gctgctgcca tatggacgtt ttgaggcggt acatgaggct agtccaactc
    11101 tgttttataa tgatgccaat cagcatgtgg ctaaaatggt agaaacgcgt attgccaata
    11161 ccaattctcc ttggctggca ggtgtcaggg tgggggatat tcatgctgtt gcagtgtcac
    11221 atggagaggg caagcttgtg gtaacagaaa gagaattagc agagctttgt aaaaatggtc
    11281 agatttttag ccagtatgtt gaccttgatg gtaatccaag catggatagc aggtataatc
    11341 caaatggctc tgtcaacgct attgaaggtc ttaccagcaa aaatggtcag attatcggta
    11401 agatgggaca ttcagagcgc tttgaagagg gacttttcca aaatattccg ggtaataagg
    11461 atcaatggtt attccgaagt gcggtgcatt attttagagg agaccatgtg ggtattgact
    11521 gaactgggat atagccttgt aatagctaag atagctgcta ttattgctca gcctagctgt
    11581 tagttctagc ttagttaatg acacaatcat aattaaaagg gcattagccc agaggtaaag
    11641 atgacatatg acgtaaaatc tcttaatgag gaatgtggtg tttttgggat ttggggacac
    11701 ccacatgccg ctcaagtgac ttattttggg cttcatagcc tacagcaccg cggccaagag
    11761 ggagcaggta ttatttcaaa tgataatggg gagcttcatc agcatcgtga tgtaggtctc
    11821 ttgtcagagg tgtttaagga ttcatctgat ctggacaagc taaagggaca tgctgccatt
    11881 ggtcatgtgc ggtatgcgac tgctgggacg gcttccatta ataatattca gcccttttta
    11941 tatcgtttta cagacgctca atttggcttg tgccacaatg gtaatttgac caatgctatg
    12001 tcattgaaaa aagcgttaga gagtgaggga gctattttta atgcctcttc tgatacagaa
    12061 attctaatgc atttgattcg tcgtagtcat cacccagaat ttttaggaaa ggtaaaagag
    12121 gcactcaaca ctgttaaagg gggctttgct tacctgctga tgacagagaa ccagctgata
    12181 gcagcgcttg atccaaacgg ctttaggccg ttgtctatag gccgtatgaa aaatggggct
    12241 tgggtcgtct caagtgagac ctgtgccttt gaagtggttg gtgctgagtg ggttcgcgat
    12301 gtgatgccag gtgaggtcat tatcattgat gatcagggga tcacttatga ctgctatacg
    12361 actactacgc agctggctat ctgctctatg gaatatattt actttgcgcg tcctgattca
    12421 accattgctg gagtcaatgt tcacaccgct cgcaagcgaa tgggaaagag actggctcag
    12481 gaatttcagc atgaggctga tattgtggtt ggtgtgccaa attcctcatt atcagcagcg
    12541 atgggctttg cagaagcatc aggcctgcca aatgaaatgg gattggtcaa gaatcaatat
    12601 acccaacgaa cctttatcca accaactcag gagcttcgtg agcagggagt tcgaatgaaa
    12661 ctttcagctg tttcaggtgt tgtcaagggc aaaagggttg tgatggtaga tgattctatt
    12721 gtcagaggga caacctcacg acgcattgtt aatttgctgc gtgaagcagg agctacagag
    12781 gttcatgtag caattggtag ccctgagctc aaataccctt gcttttatgg gattgatatt
    12841 cagacaagac gggagctgat ttcagctaat catactgctg ctgaggtctg tgatattatc
    12901 ggtgctgata gcctgactta tttgtcactt gatgggctta tcgaggctat tggacttgat
    12961 acaaaagcac caaatggtgg gctttgtgtg gcttattttg acggtcagta tccaacgccg
    13021 ctttatgatt atgaggaggc ttatctcaag agcttagaag aaaaggtaag ctttcacatt
    13081 gatcaggtga cgaagtagcg ctttatggct aacatagaat aaatgatcta ggcagctaaa
    13141 ataaggagga gaaaatgtct aaaaatgctt atgctcaatc aggtgtcgat gttgaagcag
    13201 gctatgagct tgttgagcga ataaaaaagc atgccgagcg tagcaaacga ttgggtgtta
    13261 tgggtggtct aggaggcttt ggtggtctgt ttgacctgtc aaagactggt gttaaggagc
    13321 ctgttttggt ttcagggaca gatggcgtcg gaacaaagct aatgcttgca atccagtacg
    13381 ataagcatga cacgattggg caggattgtg tggcaatgtg tgtcaatgat attattgcag
    13441 caggtgccga acccctgtat tttcttgatt accttgcagc aggaaaaaat gagcctgcca
    13501 aattagagca ggtgattgca ggtattgctg agggctgtgt tcaagcaggt gctgctctta
    13561 tcggtggaga aactgctgag atgcctggta tgtatggtca agatgactat gatcttgccg
    13621 gttttgcggt tggtattgct gagaaatctc agctgattga tggttcaaga gtagctgagg
    13681 gagatcatct cctaggtttg gcatcaagtg gagttcattc aaatggttat tccttggttc
    13741 gtcgtatttt tgccggttat actggtgagg agctgcttcc agagcttgat ggaaaaaagc
    13801 ttaaggaggt acttcttgag ccaactcgta tttatgtcaa ggctgtgtta ccactcatta
    13861 aaagcggctt agtggcagga atcgctcata ttacgggtgg cggctttatt gaaaacctac
    13921 ctcgtatgtt ttccaaagaa ctagccgctg aaattgaaga agccagctta cctgtgctgc
    13981 ccatttttaa agtccttgag acatatggta agatcaatca tgaagaaatg tttgagattt
    14041 ttaatatggg tattggcatg gtgcttgctg tcaagcctga gcacgttgag caggtgaagg
    14101 cctgtcttga tgagcctgtg tatgacattg gtcgcgttgt gaccagaaca gttgctagtg
    14161 tggtgatgaa gccatgacaa gaattgccgt ttttgcttct ggtaatggct ccaattttca
    14221 aacgattgca gaacagtttc cggttgcctt tgttttttct gatcattgcg atgctcatgt
    14281 tttaagtaga gcctgtgctt tgggtgttct gtcctacagc tttgaactaa aggactttga
    14341 gaataagcaa gcctatgagc agactcttgt ggcattgctg cagcggcatc agattgatct
    14401 catcgtcctt gccggctata tgaaaattgt gagtacaacc ttacttgatg cttacgaagg
    14461 aaaaatcatc aacattcacc cagcttattt gccagaattt ccaggagcac atggtatttt
    14521 agatgcttgg caagcaggtg ttagtcagtc aggagtgact gttcattggg ttgatagtgg
    14581 tattgataca ggaaaaatca tcaaacaggt acgagtacca cgtttgagtg atgatactct
    14641 tgaaagcttt gaagccagaa ttcatgaagc agaataccaa ttgtatccag aggtactgga
    14701 tagtcttgga gtagagcggc ttaaccgctg attgtgtaag attaataact attttcccta
    14761 ttgtggcatt tcgtttatca tagcagctgc gctaatggtg gctaacaaag gctagaagac
    14821 ttgtttgatg atggcactgc tattgaggaa aatagacttt tctaaggaga acttaaaatg
    14881 actaaacgcg ccttaattag cgtatcagat aaaagaggga ttgtggacct tgctagggag
    14941 cttaagcatc ttggctggga tattatatca acaggaggaa caaggcttgc tcttgaagag
    15001 gctggtgtag ttactgttgc tattgacgat gtgacaggct ttcctgaaat gatggacgga
    15061 cgggtaaaaa cgctgcaccc tctcattcat ggtggcttac ttgctcgtcg tgacattgag
    15121 caccacttac aggcagcaaa gcaaaacagg attgaattaa tagaccttgt tgttgttaac
    15181 ctttatccct tcaaagaaac catttgccgt ccagatgtca cttatgatgt cgctgttgat
    15241 atggttgata ttggtggtcc ttcactgctg cgttcagcgg ctaaaaatca tgctagtgtt
    15301 acggtagtgg ttgatccgac agattatccg ctcgttttag gagagttggc tagcactggc
    15361 agtacaagtt accaaacccg tcaaagctta gcagctaaag cttttcgcca tactgcagcc
    15421 tatgatgcag tgattgcaga ttattttaca agacaagcag gtgagacaaa gcctgaaaag
    15481 ctcacgctta cctatgattt gaagcaaagc atgcgttacg gtgaaaatcc tcaacaggct
    15541 gcagattttt accaaagagc gctcccaaca acctattcaa ttgcttcagc caagcagcta
    15601 aatggaaaag agctatcatt caacaatatt cgtgatgcag atgctgcgat tcgtattatt
    15661 cgtgatttta aggagcgtcc aaccgttgta gcactcaagc atatgaatcc atgtggtatt
    15721 ggtcaggcag atgatattga gacagcttgg gattttgctt atgcagctga tccggtgtct
    15781 atctttggtg gtattgttgt cctaaatcgt gaggtggatc tagcgacagc ggagaagctt
    15841 catgctattt ttcttgaatt gatcattgca ccaggctatt ccaaagaagc gctagctgtt
    15901 ctcacccata aaaagaagca cttgcgaatt cttgaattgc catttgctgc tcaggaggct
    15961 agtgaaatag aagcagaata tacaggagtt cttggtggtc tactagtgca aaatcaagat
    16021 gttgtcacag agtctccagc ggattggata gtggtgacaa agcgtcagcc aaatgaacag
    16081 gaaatggctg ctctagcatt tgcttggaaa accatcaaat atgtcaagtc taatgcgatt
    16141 gtcattgcta atgatcatat gactttgggc gttggtccag ggcaaacaaa ccgaatagcc
    16201 tctattcgta ttgctattgc gcaagcaacg gggcagcttg agggagcagt tcttgctagc
    16261 gatgccttct tcccatttgc agacagcatt gaagaaattg ctgccgctgg tatcaaggct
    16321 attatccagc ctggaggctc tattcgtgat tcagaatcta ttgcagctgc caatcagcat
    16381 ggtataacca tgattttcac aggtgtgagg cattttagac attaataaag taaaaagaga
    16441 ctggagccaa aagagttgca ctttagaaat tcttggttaa tatactttat tacctagttg
    16501 gattcattaa aaagcgaaca agtctagttt tcataatctc agaaaactag acttgtttgc
    16561 ttgttttatt tggtggtcat actattgttt cagcctcttt ttactatgac taatacaaga
    16621 atttatgaag gaacaaggct ttattttttg ttgtggtaac agtgaccaga tccgttatca
    16681 atcagtattt gagtattttg agctctagat gcatcactta gataggatat tgcaaaggat
    16741 acagctgctg catgtattag gaaagcatta tcataaaagg ctttttcgtt agcctaaagg
    16801 ttttagacct tctttgcctt atctattgtt aaccatgttc cacgtgaacc catttgcacg
    16861 taaatcccct tgctaggctg atcaaccttt agaaccttat aggttcctga aacgacaaaa
    16921 taatcaccca cctgcaaaat ctgatttcca gcaatacgtc ctttatggtc cgtttcgtgg
    16981 agtggagctg agtctatcca gtttaaggag gttggctctc caccggctaa ttcactgctt
    17041 gcaatcatgt tctgagcgac ctgatcgacc cgaaaaacac caggaaaggc tacagtatct
    17101 ccaaccttga taggagtggt cgccacaggc tttggtttat ctatagaggc ttgactatgt
    17161 tgctgaggct gaaccggcaa tttgtgaatt ggaatgtagc gatgatttcc tgaatgaccg
    17221 atatagctga gccattcata gccatcagcg acaagggttt gatcatagtg cactaactgt
    17281 ccagtatgat agtaagctaa atcaggactt gctaatgtag cttcagcctt tataggactt
    17341 tggcttgaaa aataataggt accactttta gctagacgag ttgatcctgc ttgagaagca
    17401 tgtaacattt gtgtgtggct ggtagagttg tgatccagat ccttgaagtg aatgtaacca
    17461 cttacctgat gcttatgaat ctgtcgttta tgatactttt caggtccctg tccggcatta
    17521 tagttgtatt cctcaataat aacagtgtca ccattgacct ctgctaccca ggcgacgtgt
    17581 ccatataggg catgtgactg gttaaagccc ttatcccacc aagcaacagc accaactcta
    17641 ggtgtatgat caacatgata gccttggtgt ttagctatac gtccccagct ttcaacatta
    17701 ccatagcctc taggcaggct gaatccattt gaggaatgca gtcggaatgc tacaaaagaa
    17761 gtgcattgac gtaagtacat gttccaagga tcagctccga agccctgttt ccacttactt
    17821 ggatagttat cccctaaaac agcagcgtgt acgatacctg actgaccttg tgaaatcgtt
    17881 gttgtggcag aggatattgc accattacca cctaaaagga ttgctcctga agctaacaat
    17941 tgatagactt ttttcattaa ttacctcctg taacttacta ttcgcaagaa agaggacaaa
    18001 aatgtccttg atttaaaaaa atgtaaggaa aaatatttta gcctcaaaat actgttggtg
    18061 ctccctagct tccaagagcc aataggcaag cccatctcca gcttgcctgc tccctgtagc
    18121 taaaagcaat ttatagtaac actagcacct catctgaaga ggcaggctgt ggtaattaat
    18181 gccaataatc tgtaaaaaga gacagcaggt atggttatat gagctatgat ggttatattc
    18241 tataaagctt attttttagc ttcgggcttt ctttggtgat tagttattta tataaacgaa
    18301 caattatgct aaaatatgtt tataaaattc gtgttatgag gtgtgtgatg aagcttttag
    18361 ttatcggttc aggtggtcgt gaacatgcga ttgctaagaa attgttagag tcaaaaggcg
    18421 ttgaacaggt ttttgtggca cctggcaatg atggcatgac ccttgatggc atagaacggg
    18481 tagatattga tatttccgaa cattctgctt tgattgcttt tgcaaagacc aatcatatag
    18541 cctggacctt tgtgggacca gatgacgcat tagcggctgg tatcgttgat gagtttaacc
    18601 agtctggctt gaaagccttt gggccctctc gtttagcagc ggagctggag tggtcaaagg
    18661 actttgctaa gcaaatcatg gtcaaatacg gtattccaac agcagcctat ggcacatttt
    18721 ctgattttgc aaaagccaag gcctacatcg aggaaaaggg cgcgccaatt gtggttaaag
    18781 cagatggttt ggcgctagga aagggtgttg tcgtagcaga gactgtagag caggcagttg
    18841 aggcggcgcg tgacatgctc ttggataata aatttggtga ttcaggtgcg cgcgtggtga
    18901 ttgaggaatt tttagctggt gaagagttct ctctctttgc ctttgtgaat ggcgatcagt
    18961 tttacctcat gccgacagcg caggaccaca agcgggctct tgatggtgac aaggggccaa
    19021 atacaggtgg tatgggggct tatgcaccag tgcctcatct ttctcaaagt gtggtggata
    19081 cagcagttga gaccattgtc aagcctgttc taaaagggat gatgacagag gggcgtccct
    19141 atcttggaat cctttactgt ggcttgattt tgacagaaga tggaccaaaa gtgattgaat
    19201 tcaatgctcg ctttggtgat cctgagactc aggttatcct tcctcgcctg acctctgatt
    19261 ttgcacagaa cattaccgat atattagagg gcaacacagc taatatcaca tggtcagacg
    19321 agggagtgac gctcggcgtt gtccttgctt caaacggtta tccgcttgct tacaagaaag
    19381 gtgtgcttct gccagcaaag accactggcg acatcattac ctactacgca ggggttaagc
    19441 ttgcggaaaa tggcaaagca ctgctgtcaa atggtggacg tgtctatatg ctggtcacca
    19501 cagcagttac cgtcccagct gcgcaagaaa aaatctatac cgaacttgct cagcaaaata
    19561 ccgaaggatt attctaccga aacgatattg gaagaaaagc agtaaaataa attagcgcta
    19621 gctcaagcta ccgaaggtcg ctatgatgac aatgacttat tatcggtgag caaaagcgag
    19681 cctaacacga tacttttcgc cgtagcgcaa agagtgacaa ggtcactcgg gggaacttga
    19741 aagaccttgg gctttcaagt tagtcatgag acacctatgg tggctgttga cgcccccccc
    19801 cacttaagaa aagtatcaaa aacctttaag gagaaagtat gaaaccaatt atctctatca
    19861 tcatgggctc caaatctgac tggaccacca tgcaaaaaac cgccgaaatc ctcgaccagt
    19921 ttggccttgc ctacgaaaaa aaagtggtct ctgcccaccg cacgccggat ctcatgttca
    19981 catacgctga gaaagcacgc gaacgtggca ttaaaatcat catcgctggt gctggcggag
    20041 cagcccatct ccctggaatg gtcgctgcaa agacgacact tcctgttatc ggcgtacctg
    20101 tcaaatcgcg tgctcttagt ggtcttgatt cgctgtattc aattgtgcag atgccaggtg
    20161 gtgtgcctgt ggcaactatg gccattggag aggcaggagc aaccaatgca gcactgactg
    20221 ctcttcggat cctttcaatt gaggatgaaa caatcgcaga gcagctcagc catttccaca
    20281 aagagcaagg acggatcgca gaggagtcaa cccatgaact caactaaaac aattggaatt
    20341 atcggaggtg gtcagctggg acagatgatg gcgatttctg ccatttatat ggggcataag
    20401 gtcattacac tggatccagc agcggattgc ccagcctcgc gcgtgagtga ggttatcgtg
    20461 gcgccttata gtgatgtgga ggcgctgcgt caattgaccg agcgctgtga tattttgacc
    20521 tatgaatttg aaaatgtgga cgctgacgcc cttgatacag tggtaaagga ggagcagctg
    20581 cctcaaggaa cagagttact tcggatctcg cagaatcgta tttttgaaaa agatttttta
    20641 gccaataaag caagcgcggc agtggcaccc tacaaggttg taacctctag cctcgacttg
    20701 gaaaaccttg acttttcgaa aaaatacgtc ctcaagacag cgacaggtgg ctatgatgga
    20761 cacggtcaag tcgttattcg ctccgaagca gaccttgaag aggctaataa gttggctaac
    20821 actgccgagt gcgtcttgga agaatttgtc agctttgacc gagagatttc cgttattgta
    20881 tctggcaatg gcacagatgt cactgtcttt cctgttcagg aaaatatcca tcggaacaat
    20941 atcctgtcaa aaaccattgt cccagctcgc atttcagaag cagttagcgc taaatcgcag
    21001 gctatggcgg tgaaaatagc agagcagctt aacctatctg gcaccctctg tgtagaaatg
    21061 tttgtggcag gcgacgagat tttggtcaat gaaatcgccc cacgtcccca caactcagga
    21121 cattactcca tcgaagcctg tgatttctcc cagtttgaca cccacatttt aggtgtatta
    21181 ggccagccat taccagctgt caaactccat gccccagcca ttatgctcaa cgtcctcggc
    21241 cagcacatgg aacaagccca acgctacgcc acagaaaacc ctagcgccca cctccacctc
    21301 tatggtaaaa tagaagccaa gcacaaccgc aaaatgggac acgtgacggt gtttaacagt
    21361 caatcagatg aggttgaaga attttaggag gaattaatcc tatgataaaa atcattgttc
    21421 acgcttttat tgaaaatggt gaaacaggtg ttgttgaagt tgtctttgct tcggaaaacc
    21481 aagaatccat ttctgaaaaa atgacggagc tacaaaagca atatccaaac gattaccttg
    21541 ctatctatga tttaccacta gatacagacc tatcgcaatt ggcccactat ccgtcaatag
    21601 cgataggcaa aggggagttt gagtagttaa ggaagattag tatttcggat tgagtgttat
    21661 tgggacaatt tatggctatg cctttcaaaa gattggtcat gatgttgagc atgttgtgag
    21721 aattgagaat cgtaatcaga tttcagaagt tggtaaatga cttaatggat aattctagat
    21781 actgatctcg agcaatcata agagaaatgt tgaaattgta gcttctggag gtgtagaact
    21841 caaaaattat cgtggtgaga tatttccata taaaacttct aagcgtattt cgtctagatt
    21901 gataacatat agataggttt gtacataatg aacttactag atgcatcatg acaaagcaga
    21961 tcttttatat acatgcaaag aggtttacaa tattggtata gtcaactatt gatgccctaa
    22021 cttttaatca caatatagaa attattgcga atagacttta aaagcattac tattaactat
    22081 gtagaaagga aatgagcgct agaattttca aactgaacct gagcggaaag ctcggaattt
    22141 agataaattt cctcggacgt aaatgtccgt ctttagcttt ctaaaattca gttgctttct
    22201 ggctgttctt ggtatcttaa ttatgctaaa ccgttattca cgccctgaga tggcgaagat
    22261 ttggagtgaa gagaacaagt accgtgcttg gttggaggtg gaaatcctcg ctgatgaggc
    22321 atgggctgag ttgggtgaga ttcccaagga agatgtggcg aagattcgcg ccaatgcgag
    22381 ttttgacatc aatcgtattt tggagattga agaagagacc cgtcacgatg tggtggcctt
    22441 tactcgtgcg gtgtctgaaa cgctcggtga ggagcgcaag tgggtccact atggcttgac
    22501 atcgactgac gtggtggata cggcctatgg ctatctctac aagcaggcta atgacattat
    22561 ccgtcgtgac cttgaaaact ttaccaacat tgtggctgag aaggctaagg agcacaaaat
    22621 gactatcatg atggggcgta ctcatggtgt gcacgcggag ccaacgacct tcggtctcaa
    22681 attggcgacc tggtacagtg aaatgaagcg taatcaagag cgttttgagc atgcggctgc
    22741 tggtgttgag gccggtaaaa tctcaggtgc tgttggaaac tttgccaata tcccaccatt
    22801 tgttgaggag tatgtctgtg gcaagctagg cattcgcccg caggaaatct caactcaggt
    22861 cttgccacga gaccttcatg ccgagtactt cgcagtgctt gctagtatcg cgacatcaat
    22921 tgaacgcatg gcaactgaaa ttcgaggcct gcaaaaatct gagcaacgtg aggtagaaga
    22981 gttctttgcc aaaggacaaa agggaagctc tgccatgcct cataagcgta acccgatcgg
    23041 ctctgaaaac atgacggggc ttgcgcgtgt cattcgtggg cacatggtga cagcctatga
    23101 gaacgtggcg ctttggcatg agcgtgatat ttcgcactcg tcagcagagc ggattatcac
    23161 accagacacg actatcctca tcaactacat gctcaaccgt tttggcaata tcgtcaaaaa
    23221 tttgacagtc tttccagaaa acatgactcg taacatgaac tctacctttg gcttgattta
    23281 cagccaacgt gtgatgctta agctgatcga aaaaggcatg acgcgtgagg aggcgtatga
    23341 cttggtacag ccaaagacag cctattcatg ggacaaccaa gtggacttca agccgatcct
    23401 tgaggcagac gaaaatatca ctgcaaaatt aaggcaagat gagcttgatg agctcttcaa
    23461 tccagcttat tataccaagc gtgtcgatgc tattttcgac cgattaggat tataggaaga
    23521 aaacagcgcg tctttttaga ctgtagctaa gcccagattt gtttaaaaag tcttgaaaat
    23581 gaattcctcg gagctaattc tcaaaatgaa gaatagtatt tcaagagagg ctgtcactag
    23641 ctatatcgct taagaaaatg ctctaaaata gacatttttt caatctgaga aggcaatagg
    23701 ccttcttttt ttctaaaaat acagaaatgt tattatagaa tggagtcaaa aaattaataa
    23761 ttaattaaat tatgtgatat aatgaaagaa atagtgtctt gaagagggaa acatgttaga
    23821 caattttggt gaaaaggtga gagaccttcg gtatcagaaa aaaattacca gagaggattt
    23881 atgtggagat gagtcagaat tatccattcg tcaattggca cgaatagaac tgggccaatc
    23941 gattcccagc ctatcaaagg tggtttttat tgctaaggct ttggacgtta gtgtcggctt
    24001 tttgacagac ggagaggatt tggagctacc gaagcgctat aggagcttaa atatttgatt
    24061 ttaagaacac cgacctatat ggacgatgac aaattaaagc tgcgagaaga gcaatttgac
    24121 gaaatttttg aagattatta tgaccagttg ccagaggaag aaaagcttgt ggtggattgc
    24181 ttgcagtcca taatggatac gttattaacc gagaatatca attttggagt tgggttatta
    24241 caggaatact ttgaacaaac aaaaagtaag actcaattta gagagaatga tctcattctt
    24301 attgagctgt atttagcgta cctcgacatt gcaggaatga atggagagta ttcagataaa
    24361 ggattctatg attctttgtt agacattttg ttaaatcagt ttgaacattt tgaattagag
    24421 gaattattta ttgtcaataa aatagctata ggaatttcct cgttgagcat caaaaacaat
    24481 aagccggaga ttcttgagaa ggttattgta cttagtcaaa aaattatcct caagactcag
    24541 gattttaata gaatgcctat cttaaatttg atagagtgga aatatgctct aatgaagaaa
    24601 aaagacatag aaatggccaa aaaatgctat gctaaggcat gcctgtttgc tcaattaaca
    24661 ggagatcagt atttggaaaa gaaattgaga gaagaatggg gtaaagatat aaaacgatat
    24721 caataggaca aaaatgtcat ttttatcaaa aatggaataa tatataatct ttatataaca
    24781 aataattgat taaaggagtt ccatttatat gtttaaaaaa taccaatact atctgttttt
    24841 agctgcttta tttctacttc attctgccca attacttagt gatattgact ggtggcgtgt
    24901 tggttaaagc taaatcatct atttatgcta taatagctct atgacaagaa ttttagataa
    24961 tgatctgata ggcgatgaag gatctgttga gaggacacta cgtccacagt atttacgtga
    25021 gtatattggt caggataggg ttaaagacca gctgatgatt tttattgagg cagccaagag
    25081 gcgtgaggaa tccttggatc atgtcctgtt atttggttcc ccaggcttgg gtaaaacaac
    25141 gatggccttt gtcattgcca atgaattggg agttcatctc aagcagacct ctggcccagc
    25201 cattgaaaaa gctggtgatt tggtggcaat tttgaatgat ttagagccag gagatgtcct
    25261 ctttattgat gaaattcatc gtatgccgat ggctgttgag gaaatcttgt acagtgccat
    25321 ggaggatttt tacattgata tcatgattgg cgctggagac actagccgga gtgtgcattt
    25381 ggagctgcct ccctttacat taattggagc aacgactcgt gcaggcatgc tgtcaaatcc
    25441 tttgagggct cgttttggga ttactgggca tatggaatat tatcagacag ctgatttaac
    25501 agagattgtg gagcgtacag ctgatatttt tgacatgaca atcaagcatg aggccgctta
    25561 tgaactggca cgcaggagtc gtggaacccc tcgtattgct aatcggctgt taaaaagggt
    25621 gcgtgattat gctcaaatta tgggtgatgg aatgattacg actcaaatca cagataaggc
    25681 tctaacgatg ttagatgtgg atcaagaagg tttagattat gtggaccaaa agattcttcg
    25741 taccatgatt gaggtgtacc aaggagggcc ggttggtctt gggactctat ctgtcaatat
    25801 agcagaggag cgagatacag tagaagacat gtacgagcct tatttaattc aaaagggttt
    25861 tatcatgcgt accagaacag gccgagttgt caccgaaaaa gcctatcagc acttaggcta
    25921 tccctatgaa aaaaccatta agacataaat agctatgtaa gacttgattc ctttgttttt
    25981 accggtgtca agtcttttgt attgtcaata gcttactgag taaaaaagta aaacgatgtg
    26041 aggtgagggg tgattggtca gggaagcaga ggtgctttca ctagacaaag cattaaaaaa
    26101 catttttaga tcaattgaac gaaaattata agagcgattt ctccttttgg ccctataatt
    26161 ttgctataat aggtaaaagg agtttttcat gaaaaaagta tgctttgttt gtcttggaaa
    26221 tatttgtcgt agtcctatgg ccgaatttgt catgaaaagt atggccagtc ctgatgagct
    26281 acaggtggag agtcgtgcaa cctctggctg ggagcatggc aatccaattc atcatgggac
    26341 acaatcgcta ttacagcaat atcagattag ctatgatacc aagaaaacct ctcagcaaat
    26401 caccagcttt gactttgaag cctttgacta tattatcgga atggatagcc ataatatcag
    26461 agatttgaag caaatgtcca agcatcagtg ggattccaag atccatcttt ttattgaagg
    26521 aggcgttccg gatccttggt atacaggaga ttttgaagaa acctaccgct tggttaaagc
    26581 gggctgtcag cattggttga gtcaaatcag cgctgaacat gaatcacatg tggaaataga
    26641 tgagtaatag taatgaaagc aataataaat aacattcaaa aatggcagat cactcggaca
    26701 aagctagaga ttatttcagt ccttgtgatt attgtctgtg gattgtcggt ttttaccttg
    26761 accatatcct caaaagcaag cttgacctat gacaatgggc aaatcaagta caccggctat
    26821 gtccttaatc atagaatgaa tggtaaaggg aaattggttt accctaatgg cgatacctat
    26881 gttggggatt ttaataaagg tgtctttgat ggagaaggaa cgtttacagc tagtacaggg
    26941 tggtcttaca gcggacaatt taaaaaaggt caggctgatg gcaagggtac tttgaaggcg
    27001 aaggattcaa aggtttacaa aggaaccttt aagcagggga tatttcaaaa atgaggataa
    27061 aatggttttc gtttattagg gtaacaggtc ttttgctggt gttgctctat cactttttta
    27121 agcatacttt ttcaggaggc tttgttggcg ttgacatctt ctttactttt tcaggctatt
    27181 tgattacagc cttgttgatt gatgaatatg tctcaaaaca aaccattgat gtggttgctt
    27241 tttttagaag gcgtttttat cgtattgtac cgccgcttgt cttgttaatt ctcttgacaa
    27301 ttccctttac ttttttagtc aaaagtgact tcattgctgg tatcggtcag caaatagcag
    27361 ctgccctagg gtttacaaca aatagttatg agctactgac aggcagtagc tatgaaagtc
    27421 aattcattcc gcatctgttt gtgcatacct ggagcttggc cattgaggtg catttttatt
    27481 tgctttgggg gctgttggtt tggttattag ctaaaaaagg ctacagtcag aagaaattta
    27541 gaggcattct gtttttaatt tcttccgcag tgttcacgct tagctacttc agcatgttta
    27601 tcagagcctt ctttgtatca gatttttctt ctgtttactt ttcaacgctt tcacacagct
    27661 ttcctttctt tttaggagcg atgtttgcaa ccatgacggg aattaaggac acgactgttc
    27721 gctttcaaaa gaatgttaag ctgtggccaa ggctacatgt tattggagtg atggctggcg
    27781 cttttgctct gttgttgttt ctaacgcttg tgttagattt taaccatatc tttacctatc
    27841 ttttcggttt tgtcttagcc agtctttttg cttcggtaat gatttatgct gcgcgtgttt
    27901 tgagcgatca aacaccaacc tggcaggaac cactgcttgt gacctatctt gcggatatta
    27961 gctatgggat ttatttattc cattggccat tttacattat ttttacacag ctgatgtcta
    28021 actggctggc agtgatctta acggttttct tttcagtagt gttttcaacg ctttcttatt
    28081 acattattga gcctttgatt caaggcaaga caccacagct ttttggttta gcaattgatt
    28141 gtaatcccta taagaaatgg ttatcagggc ttgctttagg actctttttg ttgatggttg
    28201 gtacctgttt gacagcacca agggtcggta attttgagac ccagctttta gtagattcct
    28261 tgcagcaatc tcaaagtaat ctcaataaga cacatacttt ggcagcagga gatgcgcatg
    28321 ctcttagtga tgttagcatt attggtgact cagttgcctt gaggtctagt gacgcttttt
    28381 caaaattaat gccgactgct caactagacg ctgctgtcag ccgcaatttc agtgaagcct
    28441 ttgagctttt tgaaaatcat atccaatcca agagcttatc aaaaacaacg gttttagctg
    28501 ttggtgttaa ttctctttat aattatgcgc aggatattca aggctttatt tatgcactac
    28561 caaaggggca tcgcttggtg attgtgtcgc cctatgatgc taagaatgca gcacaggtag
    28621 cagaggctag agagcatttg ttgcagctag ctaaaaaata tagctatgta acagttgctg
    28681 actggtacaa ggcggcagtc gaaaatccca atatctggta tggtagtgat ggggtccact
    28741 acaataacga cgccaaatta aaaggtgctg acttatatgt ctcaacgatt caggcggctg
    28801 ttgagcgagc agcaaaaaaa gatgctaaat agtggtgcta acaacaattt gttaagaatt
    28861 aataacgaag gcttggtctt acaaacagat caagcctttt catgatgtga tttttagatc
    28921 gtcttgcgcc ctttagcgcg agataaagct ccacctgtta gacagtgtca ttattggctg
    28981 ttattgctga cggtgacgtg cttttaaaaa cggatcatta aataatttag cctgatctaa
    29041 aaaaagaaag cgctttcgga acaaagtgaa tgcgtcagcc attatttcag aaaaaatcca
    29101 ccaagccaaa ccccttgtta tcaaagagtt tcggaaattg attgaaaaaa catcacaatt
    29161 ttattgtgaa atgatttaca aaatgccaaa aaatgatata atatttttgt aaacaaaatt
    29221 gtgaaacttt taacaaggta aaggagtctc aaatgactga aaaaaatagt actgttgaaa
    29281 caacatctgt tgccgcaaca attgacgctc ttgttcaaaa aggtttagta gcgcttgata
    29341 aaatgcgtca gttaactcaa gaacaggttg actacattgt agcgaaggcc tctgttgctg
    29401 ctttggacgc acatggtgag ttagctaagc atgcctatga agaaactggt cgcggagttt
    29461 ttgaagataa ggctaccaaa aaccttttcg catgtgagca cgttgttaat aacatgcgtc
    29521 accaaaaaac agtaggtatc attgaagaag acgatgtaac aggtttgacc ttaattgctg
    29581 agccagtagg tgttatttgt gggattaccc caacaactaa cccaacgtca acagctattt
    29641 ttaaatcttt aatctcctta aaaacacgta accctattat ttttgccttc cacccatcag
    29701 ctcaagaatc atcagctcat gcagcacgca ttgttcgtga tgcagccatt gcagcaggag
    29761 ctcctgagga ctgtgttcaa tggattgaaa ccccatcact agaagcaact aacgctctga
    29821 tgaatcatga tggtattgca acaatccttg caactggtgg taatgctatg gttaaggcag
    29881 cctactcatg tggtaagcca gctcttgggg ttggtgctgg taacgtgcct gcctatgttg
    29941 aaaaatccgc taacattcgt caggcagcac acgatattgt catgtctaaa tcatttgaca
    30001 atggtatggt ttgtgcttct gagcaggctg ttattatcga caaggagatt tatgacgagt
    30061 ttgttagtga atttaagtct taccacactt actttgtcaa caaaaaggaa aaggctctgt
    30121 tagaggaatt ctgctttggt gctaaggcta acagtaaaaa ctgtgcaggt gctaagctga
    30181 accctaatat tgttggtaag ccagcagctt ggattgctga gcaggcaggc tttacagtac
    30241 cagaaggaac gaatatcctt gcagcagaat gtaaggaagt ttctgaaaat gagccattaa
    30301 cacgtgaaaa attgtcacca gttatcgctg ttttgaaggc tgaatctcgc acagatggtg
    30361 ttgaaaaggc tcgtcaaatg gttgaattta acggacttgg tcactcagcc gctattcata
    30421 ctgctgatgc agacttagct aaggaatttg gaacaaaaat tcgtgctatt cgtgtgattt
    30481 ggaattcacc ttctacattt ggtggtatcg gtgatgttta taatgccttc ctaccgtcat
    30541 taacattggg ctgtggttct tatggacgta actcagttgg tgataatgtt agtgctgtaa
    30601 atctcttgaa catcaaaaaa gtaggaagac gtagaaataa tatgcaatgg tttaaagttc
    30661 cttcaaaaac atacttcgag cgtgattcaa ttcaatacct tcaaaaatgt cgtgacgttg
    30721 agcgtgtgat gattgttacc gaccacgcta tggttgagct tggcttctta gatcgtatca
    30781 tcgagcagct tgaccttcgt cgtaataagg ttgtttatca aatttttgca gatgttgagc
    30841 cagatcctga tatcacaacg gttatgaaag gtactgagct gatgcgtacc tttaagccag
    30901 atacgattat cgctcttggc ggtggttctc caatggacgc tgcaaaggta atgtggttat
    30961 tctatgagca accagaggtt gacttccatg atcttgttca aaaattcatg gatattcgta
    31021 aacgtgcctt caagttccct gagcttggta agaaaacaaa atttgtggct attccaacaa
    31081 cctcaggtac aggatcagag gttacaccgt ttgctgttat ctcagataag gccaacaacc
    31141 gcaagtaccc aattgctgac tattcattga caccaacggt agccattgtt gacccggcgt
    31201 tggtgcttac agtaccaggc ttcattgcag ctgatacagg tatggacgtg ttgacccacg
    31261 caaccgaggc ttacgtatca caaatggcta atgactttac agatggtttg gcccttcaag
    31321 ccattaagat tgtctttgaa aaccttgaaa aatctgttaa ggaagctgac tttgagtcac
    31381 gtgaaaaaat gcataatgcc tcaacaatgg caggtatggc ctttgctaat gccttcctgg
    31441 gtatttctca ctcaatggct cataagattg gtgcacaatt ccatactgtt catggacgta
    31501 ccaatgctat cttgcttcca tacgttattc gttacaatgg tacccgtcct gctaaaacag
    31561 caacatggcc taagtacaat tactatcgcg ccgatgaaaa atatcaagac attgctaagt
    31621 tgctaggact tccggcatct actccagaag aaggtgttga atcttatgct aaagctgttt
    31681 atgatcttgg ctgtcgctta ggcattaaga tgaatttcag agatcaagga attgatgagg
    31741 aagaatggaa ggcacacact cgtgagcttg cttatcttgc ctacgaggat caatgctcac
    31801 ctgctaaccc acgcttgcca atggttgagc acatggaaga aatcatgaat gatgcttatt
    31861 atggttacgc agagcgtcca ggacgtcgga aataatatca atcattaata gtaaaaatag
    31921 gagctgcttg gcttctattt ttttatctag ctatgaaaag ggctgtgtta gatgaaaaag
    31981 tcggcagtgc cttgtgttga gatagcttaa ctcaggggta gtttctcaga tatcatataa
    32041 agcttttaag acaatggttt tacagagcat tccatcagag ggggaagctt catttgccat
    32101 attcataaag tggctgatag ttacgactta gctgcactta gcaattagct gaagaaaata
    32161 acatgttgcg tctatctgat gagctttatt ttctaataaa acaaggagtg attgcttttt
    32221 ta
//
LOCUS       DARYUW010000019        31751 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYUW010000019 DARYUW010000000
VERSION     DARYUW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31751
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..1435)
                     /locus_tag="TVW11_000794"
     CDS             complement(<1..1435)
                     /locus_tag="TVW11_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1364911.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TVW11_000795"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TVW11_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1364912.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TVW11_000796"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TVW11_000796"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1364913.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TVW11_000797"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TVW11_000797"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1364914.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TVW11_000798"
     CDS             complement(5344..6630)
                     /locus_tag="TVW11_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1364915.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TVW11_000799"
     CDS             complement(6772..7143)
                     /locus_tag="TVW11_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1364916.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TVW11_000800"
     CDS             complement(7130..7402)
                     /locus_tag="TVW11_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1364917.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TVW11_000801"
     CDS             complement(7433..8944)
                     /locus_tag="TVW11_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1364918.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TVW11_000802"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TVW11_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1364919.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TVW11_000803"
     CDS             complement(12410..12979)
                     /locus_tag="TVW11_000803"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1364920.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TVW11_000804"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TVW11_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1364921.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TVW11_000805"
     CDS             complement(14337..14702)
                     /locus_tag="TVW11_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1364922.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TVW11_000806"
     CDS             complement(14823..15020)
                     /locus_tag="TVW11_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1364923.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TVW11_000807"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TVW11_000807"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1364924.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TVW11_000808"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TVW11_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1364925.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TVW11_000809"
     CDS             complement(17976..18749)
                     /locus_tag="TVW11_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1364926.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TVW11_000810"
     CDS             complement(18869..20092)
                     /locus_tag="TVW11_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1364927.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TVW11_000811"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TVW11_000811"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1364928.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TVW11_000812"
     tRNA            complement(21081..21154)
                     /locus_tag="TVW11_000812"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TVW11_000813"
     tRNA            21435..21506
                     /locus_tag="TVW11_000813"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TVW11_000814"
     tRNA            21539..21612
                     /locus_tag="TVW11_000814"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TVW11_000815"
     CDS             complement(21873..24458)
                     /locus_tag="TVW11_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1364929.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TVW11_000816"
     CDS             complement(24581..26200)
                     /locus_tag="TVW11_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1364930.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TVW11_000817"
     CDS             complement(26280..27152)
                     /locus_tag="TVW11_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1364931.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TVW11_000818"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TVW11_000818"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1364932.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TVW11_000819"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TVW11_000819"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1364933.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TVW11_000820"
     CDS             30654..31046
                     /locus_tag="TVW11_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1364934.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TVW11_000821"
     CDS             31121..31522
                     /locus_tag="TVW11_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1364935.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31751
                     /locus_tag="TVW11_000822"
     CDS             31519..>31751
                     /locus_tag="TVW11_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1364936.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDST"
BASE COUNT         9884 a         6364 c         5841 g         9662 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa c
//
LOCUS       DARYUW010000020        31452 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYUW010000020 DARYUW010000000
VERSION     DARYUW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31452
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..234
                     /locus_tag="TVW11_000823"
     CDS             <1..234
                     /locus_tag="TVW11_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1364937.1"
                     /translation="GPKPEPKPEPKPEPKPEPKPEAKKPEQPKPMTKPGAKKPEQSLP
                     STGDIRNPFFTPAAIAIMIAAGTIAIPKRKEED"
     gene            complement(480..794)
                     /gene="trxA"
                     /locus_tag="TVW11_000824"
     CDS             complement(480..794)
                     /gene="trxA"
                     /locus_tag="TVW11_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1364938.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            974..2293
                     /locus_tag="TVW11_000825"
     CDS             974..2293
                     /locus_tag="TVW11_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1364939.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFEQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2633..4969)
                     /locus_tag="TVW11_000826"
     CDS             complement(2633..4969)
                     /locus_tag="TVW11_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1364940.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(5042..5587)
                     /locus_tag="TVW11_000827"
     CDS             complement(5042..5587)
                     /locus_tag="TVW11_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1364941.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5587..5898)
                     /locus_tag="TVW11_000828"
     CDS             complement(5587..5898)
                     /locus_tag="TVW11_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364942.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            6016..6924
                     /locus_tag="TVW11_000829"
     CDS             6016..6924
                     /locus_tag="TVW11_000829"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1364943.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6949..7548
                     /gene="lepB"
                     /locus_tag="TVW11_000830"
     CDS             6949..7548
                     /gene="lepB"
                     /locus_tag="TVW11_000830"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1364944.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7777..10176
                     /locus_tag="TVW11_000831"
     CDS             7777..10176
                     /locus_tag="TVW11_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1364945.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10272..10757
                     /locus_tag="TVW11_000832"
     CDS             10272..10757
                     /locus_tag="TVW11_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364946.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10900..12003)
                     /gene="dinB"
                     /locus_tag="TVW11_000833"
     CDS             complement(10900..12003)
                     /gene="dinB"
                     /locus_tag="TVW11_000833"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1364947.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12212..14536
                     /gene="pflB"
                     /locus_tag="TVW11_000834"
     CDS             12212..14536
                     /gene="pflB"
                     /locus_tag="TVW11_000834"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1364948.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14842..15120
                     /locus_tag="TVW11_000835"
     CDS             14842..15120
                     /locus_tag="TVW11_000835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364949.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15284..16225)
                     /locus_tag="TVW11_000836"
     CDS             complement(15284..16225)
                     /locus_tag="TVW11_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1364950.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16222..16977)
                     /locus_tag="TVW11_000837"
     CDS             complement(16222..16977)
                     /locus_tag="TVW11_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1364951.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17470..18318)
                     /locus_tag="TVW11_000838"
     CDS             complement(17470..18318)
                     /locus_tag="TVW11_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1364952.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18420..18872)
                     /locus_tag="TVW11_000839"
     CDS             complement(18420..18872)
                     /locus_tag="TVW11_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1364953.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18892..20091)
                     /locus_tag="TVW11_000840"
     CDS             complement(18892..20091)
                     /locus_tag="TVW11_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1364954.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20260..20919
                     /locus_tag="TVW11_000841"
     CDS             20260..20919
                     /locus_tag="TVW11_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1364955.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20940..23225
                     /locus_tag="TVW11_000842"
     CDS             20940..23225
                     /locus_tag="TVW11_000842"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1364956.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23331..23723)
                     /locus_tag="TVW11_000843"
     CDS             complement(23331..23723)
                     /locus_tag="TVW11_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1364957.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23877..24134)
                     /locus_tag="TVW11_000844"
     CDS             complement(23877..24134)
                     /locus_tag="TVW11_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1364958.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24313..24687
                     /locus_tag="TVW11_000845"
                     /pseudo
     CDS             24313..24687
                     /locus_tag="TVW11_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24945..25727)
                     /locus_tag="TVW11_000846"
                     /pseudo
     CDS             complement(24945..25727)
                     /locus_tag="TVW11_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26244..27752)
                     /locus_tag="TVW11_000847"
     CDS             complement(26244..27752)
                     /locus_tag="TVW11_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1364959.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            28003..28899
                     /locus_tag="TVW11_000848"
     CDS             28003..28899
                     /locus_tag="TVW11_000848"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1364960.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28896..29159
                     /locus_tag="TVW11_000849"
     CDS             28896..29159
                     /locus_tag="TVW11_000849"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1364961.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29086..29892
                     /locus_tag="TVW11_000850"
     CDS             29086..29892
                     /locus_tag="TVW11_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1364962.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30264..31310)
                     /locus_tag="TVW11_000851"
     CDS             complement(30264..31310)
                     /locus_tag="TVW11_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1364963.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31312..>31452)
                     /locus_tag="TVW11_000852"
     CDS             complement(31312..>31452)
                     /locus_tag="TVW11_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1364964.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9400 a         7403 c         6270 g         8379 t
ORIGIN      
        1 gggcctaagc cagagcctaa gccagagcct aagccagagc ctaagccaga gcctaagcct
       61 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
      121 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      181 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      241 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      301 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      361 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      421 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      481 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      541 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      601 tgagcagtat tggggttgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      661 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      721 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      781 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      841 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      901 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      961 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
     1021 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1081 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1141 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1201 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1261 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1321 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1381 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1441 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1501 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1561 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1621 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1681 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1741 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1801 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1861 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgagc agctaacagg
     1921 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1981 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     2041 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2101 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2161 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2221 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2281 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2341 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2401 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2461 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2521 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2581 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2641 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2701 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2761 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2821 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2881 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2941 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     3001 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3061 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3121 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3181 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3241 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3301 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3361 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3421 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3481 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3541 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3601 caacataggc tgtctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3661 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3721 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3781 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3841 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3901 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3961 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     4021 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4081 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4141 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4201 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4261 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4321 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4381 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4441 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4501 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4561 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4621 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4681 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4741 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4801 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4861 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4921 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4981 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     5041 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5101 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5161 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5221 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5281 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5341 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5401 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5461 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5521 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5581 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5641 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5701 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5761 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5821 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5881 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5941 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     6001 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6061 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6121 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6181 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6241 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6301 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6361 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6421 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6481 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6541 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6601 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6661 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6721 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6781 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6841 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6901 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6961 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     7021 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7081 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7141 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7201 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7261 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7321 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7381 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7441 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7501 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7561 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7621 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7681 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7741 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7801 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7861 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7921 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7981 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     8041 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8101 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8161 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8221 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8281 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8341 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8401 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8461 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8521 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8581 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8641 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8701 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8761 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8821 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8881 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8941 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     9001 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9061 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9121 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9181 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9241 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9301 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9361 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9421 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9481 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9541 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9601 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9661 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9721 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9781 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9841 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9901 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9961 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
    10021 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10081 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10141 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10201 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10261 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10321 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10381 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10441 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10501 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10561 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10621 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10681 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10741 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10801 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10861 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10921 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10981 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    11041 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11101 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11161 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11221 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11281 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11341 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11401 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11461 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11521 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11581 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11641 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11701 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11761 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11821 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11881 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11941 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    12001 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12061 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12121 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12181 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12241 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12301 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12361 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12421 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12481 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12541 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12601 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12661 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12721 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12781 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12841 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12901 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12961 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    13021 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13081 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13141 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13201 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13261 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13321 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13381 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13441 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13501 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13561 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13621 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13681 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13741 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13801 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13861 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13921 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13981 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    14041 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14101 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14161 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14221 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14281 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14341 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14401 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14461 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14521 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14581 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14641 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14701 taaaaaaaaa aaaacgaaac tacggagaaa agctgatgag gagctcttta aggctatcag
    14761 tcaacatgtt aaactcttct taggaagcgt taacaataac taactgctaa gctaagcaat
    14821 tatctattaa ggagaataac aatgaaacga ctaaaaacac tatgcttgtt agctactgct
    14881 ataaccctaa ccctagctcc tatcagcaca agccagacaa caacacagac cgtatatgct
    14941 agtgaaactc atcaaaatct ttgtacgaac actggtaacg gatggtttaa atgtcccgat
    15001 ggacatggag ggtggacttg gcattttgac gaaaatcata agtcaaatca gcagtccttt
    15061 ttgggaggat tgttgggctt tgctttgtct ctatggggag ctattattag actcttttaa
    15121 gctctagctt aactaatcct caaacaacaa aaataagctc ttagagaact aagctctaag
    15181 ggctttttgc tgttctgata agtaaaaacc aagagacaag gacatcaaaa acaagcaggc
    15241 ctatcagata taccacctga taggcccact tgtgctctca ttcttatcta ggactatttc
    15301 tgtcaaaggt cctatgaata gcatcccgaa gctgtcgtct ctctttgatc cacaaggccc
    15361 tatcatcctt gtcataggtt ctattggtga gaaaaatcgc tgcctgctgc tcctttttat
    15421 tgagcatgat aaaaggccct gtatagcctg tatgactaat ccaatcaccc tctaggctcc
    15481 aacccaaaga cctgggcttt tcctgtctgc tatagctttg aaaaagtcta tccgaaaagc
    15541 tttccttcag gtaatgctca ataaaccgct ctaaatccct gatggttgaa aaaagccctg
    15601 ctgagcctgc atggtttccc aagaccttag ccttgggatc atgtacctct ccatcaagca
    15661 cccctttgac cgttggaact gcttctggcc ttgggccaaa ggaggtctca gtcattccaa
    15721 agggagtaaa aaccatctcc tgaaaaagct catcaagaga ctttccatga aggtgctcta
    15781 gcatgaagcc aagcaataaa aaattcacat ctgtgtaatg aaaggtctta tcgtccttga
    15841 cctgaagctg gtgcatcgct gctcttaatt gctgggcatt gagctgatct cgattgggaa
    15901 tataagggtc aagtccacta gtatgggtga gtagctgtcg cagtgtaacc tccagctttt
    15961 gagcgtcagg ataataatgc cttaaaggag tatcaagagc caaggcacca ctattgatca
    16021 tggctataca gacagtcgct actccgacaa ccttagagac actggctaaa tcataaacca
    16081 agcctttggt aacaggtctt tgaccatcaa gggtaccgat ataatgctcc tgccaaccgc
    16141 cacagcgaaa aagggctaag ctagccccat gatataagcc ttcctgaatc tgctggctta
    16201 ccttttctat gacttctaat gtcatttgac aaaccaaatt tcgatctgac ttgggtctga
    16261 aagaacaagc acccttgcct ttttatctaa ataaacctga caccctttgt cctcaaggta
    16321 ggtctttaga gcaagcaagt catagctatc tgacacctga aattctaaaa tctccaaatc
    16381 ccatgtgaca tgcgggacaa tcgtcaaatc ttgaccagcc tccctattaa actcaagcgt
    16441 gaccggcagg caatcaccaa aaatagactg ataaaaagct ctggattgct cgtcatctaa
    16501 aacatttaag acaatcagat caaagctaaa ctgactcagc cccctaaagt cagcttcctt
    16561 gtcaattgca ggaacatcat cgacaatgtc aagctccttg atatcgtcct ctgcatggag
    16621 taagaagcga tctccctctg gtgaggtgac ttcaaaggca tagccttttt ttcccttgaa
    16681 aatcaaatca tagtcaacgc catgagctag gagctgctca atgtccttag gagcagttgt
    16741 tttgataaca attgtattta ctttcttagg gccatctaca acgcgtgttc ttgctgctgg
    16801 agattcttca attacaaagc gttcttgtcc ttggccccaa gatgaaaaaa ttgatatcgc
    16861 gttttcctct gacactagcc ttaagcctag atttttttgg taaaaggcaa tattaaggtc
    16921 gcgattgtta acacgtaata ctggggtttt aaagacaata ttgtcaaata aagtcatata
    16981 ttcctcctaa tcctctgcta ttatagacaa aattccaatt tttgacaaga aattatatgc
    17041 tttttaaccg cctgtcacgc gctaccaagg caatatagca ctcacagcca tcaccagact
    17101 tactaggtcc aatcttcctt cgtgcgctct atcacaagca gctttcctta gcgtaactca
    17161 tgcacatatt ggtaaatgcg actttttcaa aatagcacat gaagtacccc tttaatttga
    17221 cttttcctta accaaaagcg agaacctttt ttagttctca cagtagcaat cacactcttg
    17281 aaatgtgatt tcgctctcct caataacaga tgataactga aattgcccgg attttcttat
    17341 ccacgcgcaa cttcaaaagc accttatctt cagcattagt aaggatacta ccagcttagc
    17401 tcagaccaga ttcagctggc tcttgctggc aagcttttat cacaaaaaag aaggcctaag
    17461 ccttcttttt tacttgatat aaaggaattt gaatgctgct actgctgcta ctgctgctag
    17521 cactggggca gcaaccggta cccatgagta ccaccatttt gaatccccct tggcttgtcc
    17581 aaggactgat tttggtaaga aatggtgaac caaacgaggg cctaagtcac gcgctgggtt
    17641 gagcgctgga ccagtaggac caccaagaga ggtcacaaga gtcatcacca agaaaccaat
    17701 ccccaagtga gctactgcaa gtgagcctgt cacgtaagga gagatttgcg ttgcagctgt
    17761 tgtttggtca tagccagcct ctaccagctt accaacaagc tccacaccaa agtaattctt
    17821 ggttaaggcc attgcgccaa aaaagaggac aaaggaacca acaaactcgt tcaaaaagcc
    17881 attaatgtag gctgccttac ggctgctctt gtcaccatca tcaactgctg aaatcgttga
    17941 gaaggatccc aaaatattgt tagggttgtc tgtctgcaca aaataaggct tgtacaccgc
    18001 aacaaccact aattggccaa acatagcccc tagcaattga gcaagaacat attgtaaaac
    18061 gtgtgcccaa gggaacaagc ctgaaactgc caagccaaag gtaaaagctg ggttaatgtg
    18121 atttccagaa acgttaccaa acataagtgc cggcatcatc acaccgaggc catagccaaa
    18181 ggcaatcaca agccagcctg agcggttacc ctttgttccc tttaagtcaa cattggcaac
    18241 tgctccattt cccaaaataa tcaaaaatgc agtggcaata aactctgtga tgtatttcac
    18301 agtccatgtt atttccatat tctctagttt cctccaaatg ataagtataa cagataccat
    18361 tttatcaggg atactagttc ttgtaaagcc tattgtaaga tattgcctgc ttaatatgtt
    18421 tacagtgttt tttcacaatt acggacaact aataagtctt ttttagcatg tcgcaggata
    18481 tactctgagg tcgatccaat cagcagacgc tcaaaggtat ttaagccagt tgctcctacc
    18541 atgatcaaat cagcctgctc cttttcaggt atgtcactag ctaagagctt tttagggttg
    18601 cctctttcga tgattttttt aatgctgcta acgcctctgc ctctagccat tttctcgtaa
    18661 tagcgcaaca cctccttggc atgctcctct tgtgtgtcaa agacataatc actaaccatt
    18721 gcatcaccct gataggcctt aacatcaata acatgagcca gcagtaagac cgcatcattg
    18781 cgaagggcaa cattaatggc cttctcaaca gctaattctg attcgtaaga gccgtccacc
    18841 gcagccagaa tccgtttata tttgcttatc atctttgtct cctttcgttg attagccttt
    18901 atcaatagcc tttgcttgtg tctttaggaa atacatgact gcgcaggcag ctggaatgag
    18961 ccctgccagc cagaacaatt gatgaaagga ctgcacacca gacccaagaa gcatatcctt
    19021 gatgagtccc aacagataag gtcccgcacc caagcccaaa tctagcccaa tcatataagt
    19081 agacatagcg gtattaaagc gatgctcctc aacccccttg atggaggctg cctgtccgca
    19141 ggacataaag gttccatagc caaagcctat caaagcaccc gaaagcagat agggaaggct
    19201 gcttgtcaca ctaccaagca ggaaaagccc tagcgccaaa aagagatagc tgggataaag
    19261 aacccactgc tcccccttaa cgtccatcaa gcgtcccata gcaggtcgtg tgatcgtaat
    19321 gatcaaggca tataccacaa agaaataggc tcccaccgtc gtcaaatgaa tgtctgttgt
    19381 gtataatttt tgaaagccta gcacagaagc ataggcaatc cccatcaaaa aggcaatcaa
    19441 ggtgataaat aaggcctttc gctcaataaa gctatcaact gtccaggatt ttgtttttgc
    19501 cagctgctct gagttgaggg caatatctgt cacaggaaag gcaaaggccc ctagcacaac
    19561 tactgcgatc aacacactgc acaaaataat aatcatccga aaatcaatgt gcaaattatc
    19621 cagcataaag gtcccaacaa aaggaccaat cgccgccgct aggcttgttg atagaccata
    19681 aaaattaatc ccctctccgc gcttgctagc tggaatatag gcagtcacaa tggtattggt
    19741 tgctgttgag acaacaccat agccaaagcc attaaacaag cgcacaaaat acatcatgcc
    19801 aatcgttggc atgaaaaagt aggctagcgt tgttaggaga taaaaaatgg cgcctcctct
    19861 tagcactaag cgtcggccaa aaacctccaa ttgcttgcca aaaatcagtc gagccagcag
    19921 ggttcctagg atataaatcc ccgtcgccag acctgcctca ctggtcttag ctcctaattc
    19981 cttagtcgca acaaaggcaa tgatcaccgt aaacaagtaa tagaccatat acacaataaa
    20041 atttaatact gtgatcccta taaaatgctt gttaaataat ttgtcttcca ctgaaaatga
    20101 gctcctccct atttcattaa cattttacaa aaaaatcaga taatgcccca tttcaatggt
    20161 ataatatagg tgatactatt aaacgacatt agcaaatgct aagcattgct gcagcaacaa
    20221 attatataat gataccagaa acacctctag gagaaaagcg tgaaccatca aatcttacag
    20281 cgttatattg acagtcataa ctttcctatt atcgaaaagg gctaccacaa atacctgacc
    20341 tttgaaagct tagaggagga ttttacgtat atcctaaagg agggcattgt caagcaaagc
    20401 gttctgtcaa aatatggcat ggaatttaac ctcaggtacg tcacaggcct tgagatcacc
    20461 tctgtgctta atactggcta ttccaaggac atgagagagc cctacaatgt tcgcatcgaa
    20521 tctgagactg ccagctttta taaggttcgt cattccacct ttttaaggga tattagcgag
    20581 gatatcgagc tgcagggcta tgtcaaggac ttttatcact accgcctcca aaaatcaatg
    20641 aaaaaaatgc agtgtatgct gacaaatggc cgtatcggcg ctatctctac tcagatttac
    20701 gatttaatga ccctttttgg acgccccttg gctaatggcc atatccttat tgattttatc
    20761 atcacaaatg aggagctggg caaattctgt ggcatttcga ctgccagcag tgtcagtcgt
    20821 ctcctaaagc agctcaaaaa agagggcatt attcaaatca atgaccagca tatcatcatt
    20881 accaatttag agaagctaaa ggataatatt gttttttaac gatttagaaa ggacgtccca
    20941 tgcgctataa tcaattgtct tacattccca ccagtctaga aacagctgta gctgagcttc
    21001 aggccctggg ctttgctgtc cagcaagagc aagcacccaa ggagaacttc gctattttcc
    21061 ttagaaagct attttttcat tttcaggata ccgattatcc cttgagccat atgattgcaa
    21121 gcaaggatct cgacctattg acctttttaa catctgatgc aacactgaca aaagaggttt
    21181 ttgatttagt ggccttacag gtccttggct ttattcctgc tgttgacttt accgatgcac
    21241 aggactttat acaaaagatt ggctttccga ttgtttttga cagccagcaa ttactactca
    21301 atttacatca gctgcttgca acccggcaga agtccggtgt gaccttgatt gatagccttg
    21361 ttagtcaggg cttgcttcct atggataatt gctaccacta cttcaacgga aaagccctag
    21421 caacctttga taccaccagc ctcattcgcg aggtggtcta tgtcgaagcg ccacttgata
    21481 ccgatcaaga cggacagctt gacctcatca aggtcaacat tatccgcccc aaggccagca
    21541 ctgctatccc aagcatgatg acagccagcc cttatcacca agggattaac gagaccgcca
    21601 acgataaaaa gctccatcgc atggaaggtg agcttagccc taaggctcct cgtaggatta
    21661 ccgttgagcc aactgatttt cagccgcttg ccaccaagcc ctcaaggctt cctgtcaatg
    21721 agtgccaaga gaccttcagc catatcagct cctacacact aaatgattat tttctagcgc
    21781 gtggctttgc caatctctat gtctcaggag tgggaacagc aggctcaact ggctttatga
    21841 caagtggtga ctacgcccag atcgaaagct ttaaggctgt tatcgattgg ctaaatggca
    21901 gagctactgc ttacacgagc cacaagcgtg actatcaaat caaggctgat tggtcaaatg
    21961 gcttagtcgc aacaactgga aaatcctatc ttggtaccat gtcaacagga ctggctacaa
    22021 caggtgttga tggcttagca gtcatcattg ctgaagctgc catttcttct tggtacgatt
    22081 attatcgtga aaatgggctg gtatgcagtc ctggtggcta cccaggagag gatctcgatg
    22141 tgctgacaga gctcacctac tcgcgtaacc tgctgccagg tgattactta cgtcacaacg
    22201 accattatca acagctgctg agccaacaat ctcaagctct cgagcgccaa tcaggcaact
    22261 acaatcaatt ttggcatgac cgcaactacc tgccacaggc tgatcgcatc aagtgtgagg
    22321 tcgtctacac gcatggccta caggactgga atgtgaagcc tagacaggtc tacaatatct
    22381 tcaatgccct gcctgatagc cttggaaagc accttttcct acatcatggt gagcatgtct
    22441 acatgcacaa ctggcagtca attgattttc gtgaggccat gaatgccctg ctctgtcaaa
    22501 aaatgctagg acaaaataat ggctttaccc taccaacaat catctggcag gataaccaaa
    22561 aagaacaaac ctggaaagag ctaacagcct ttggcggtca cagcaagcgt cagattgccc
    22621 taggcgatga tcatgtctta attgacaatc actatggcga agaggacttt aagcgctata
    22681 gcaaggattt tcgtgccttt aaagctgagc tttttgaagg caaggcaaat caagcagtca
    22741 ttgatattct gttagaagag gatctaccaa tcaacgggca agcctgcctt aagcttaagc
    22801 taaaatcaag tgaaaacaag gggattttgg ctgcacagct cctagattat ggcaagaaaa
    22861 aacgctttgc tgatatacct gctattcttg agctagacag cattgacaac gggcagcagt
    22921 ttgcacgtga agcgctcaag gagcttccct tcaaggacag cccataccgc gttgtcacca
    22981 agggtgtcct aaacctacag caccgcagcg acctattgac cattgaggat attccaaatg
    23041 accaatggat gaccatcacc ttccacttgc agccaaccat ctatcatatg gccaagggag
    23101 acaccctaag agtcgttctt tacacgactg attttgagca tacaatccgc gacaatagca
    23161 actatgccct aaccctagat ttggagcaat cctatctcct aatccctact gatgaggagg
    23221 aataaatcaa agcgcatcaa aaaagcctga gatcacaatg agctgcaccc caatcgttag
    23281 atcctttgtc taactgttgg agtacagctc aaagctctag gcttttttaa ctattttgaa
    23341 acctttttac cagcctcagc accagaatgc aggctgtaga cggactcgat atgaatcaag
    23401 cctgctgcct ttggtgcgcc catcttgcct tctgcccatt ccttggcagc ctcaaagaca
    23461 ggaccctctg taatgatttc cgcacgccct acaaagcgat aaccacgcaa ttgctcgcga
    23521 ttgacataag cgacctcaat tttaccatta gcctgaatat tagagcaggt ttggccgcca
    23581 gtattttcat tataaaccaa ggtttcatcg tctaacagtc tcatcgaacg cttagggcca
    23641 atattaggat taccctcatt atctacagtt actaccattg ctaattgctc agcaatcatt
    23701 tctttcattt cttctgttaa catataatct cctcttaatc gtttctatag tcagctgact
    23761 acgctttgat tatagcacag ttaagcagaa aagccgacaa aaataggtta gcttaaaaaa
    23821 gttttacagt ttacttaaga ttagaatgat tctcgctatc tagccatcac ccttgatcac
    23881 agtaaaaagg cgattagcaa gcaagcactc tttatttcat aaaatccgaa tcgtcgccca
    23941 aaaaaaatat catcaactga tatggtcaat gcctctgcaa tacctcttaa tttttcatac
    24001 ttagctcgcc taagcttttg cacatccttt tcatatctgg ctagtgtcct aacagaaatc
    24061 ccagttaacg ctgacagttc cttttgggtc tttttttgag caatcctcaa ttcctttaac
    24121 gttgcttttg acaatatttt ccctccgcct ctcatctcag gtaatattaa tgacagatga
    24181 caagtttatt atagacttcg gtttttatga agtcaagtct tttatcgcac tttccccact
    24241 tctttttcta aatcttttga tttagcttga tttgtggtat catatcctat atagaaataa
    24301 aggagaatgg aaatgtccga aaagaaaaca ttttttgcaa ctaatttaaa atatcttcgg
    24361 ctaaaaaaga atatggaaca attagaactt gctaaccttt taggacgaaa aagctcttcc
    24421 tcaatcagcg aatgagaaag aggaaagtac actccaaaat ctggtctcct gagtgacatt
    24481 gctgccatct ttgatgtcag cctgacagac ctcatggaaa aggatttaac actggaaaat
    24541 aagggagtga cttatcagct tccccaaaga gatttagtaa tgatttcaga gcagctatct
    24601 gaaaacaatt ataacaaatg gctggatttt ggtcaggatc tcttatctca tcaggataaa
    24661 gaagaaaatc acaagccaag caaataaaga gcctcacacg tcttattctc atcaagtttc
    24721 gaaaaatcac ctaccactca agcacacaaa aagccttggc agggcttcta agcataagaa
    24781 agctgtatca tatcaatacc tcagggacca tgatatgata cagctttttg tatctcactt
    24841 ttagacaagg tagccacata aagcttgcag atgacctacc tctgtattag ctaccacaac
    24901 caacagctag ctagactggc aggccctcta taagcctcag cggattatct aagcactccc
    24961 aacagctcca acaaaataaa gacataacca ataccattat ttaagatatg ggctactgtt
    25021 gaaaaataga tattcttctt ccaaacataa actaagccga gcaaaagtcc cagtccacca
    25081 tacacaacga tggaagatag ctcgctgaag gaatagatat gaaccaagcc aaatagcaat
    25141 gatgatccca acaatcgagc cagcagcata cctgtgcctg attggccctc accgattaaa
    25201 atcttgcgga aaataagctc ctcattgaag ggaccaataa tactcaccac cagaataaag
    25261 atcactgtct cgaagccctc actagcatta tagcgattag ctaaaacagc tgcattgctg
    25321 ctctcttcta aaggaaggct actgagcaaa atatttgcaa cataaagcac tgcaaaaatg
    25381 accaagaccc acaaggtatt tttgacccat tttgttgaaa actgccgcca gtccctctga
    25441 taatctgctc gataaagcca acagatccca agtgcaaaaa tcagcagatg tctcccgtaa
    25501 aataaaaagg tattcaataa aggcggaagc tcaatcacat tgctaacttg tctataaaga
    25561 tacacagcaa tgatatatag catgaccagt acagctgcac gatgacgttt gatggtatcc
    25621 aattactctt cctcaattct aataattgtc agattagcta ggctatattg ccatcagcta
    25681 atcttgatct taaatgtgac taatttacaa gcactcaact tttgaatcgg taaagctgac
    25741 agacagccct accctagctt caataaagct atcttccaat agtccttgcg ctcatcagaa
    25801 ctgtcaaagg cctgacccag ctgagtcaac agacttatcc agtcaacatc acacagaaca
    25861 agaccatctt accatatccc tgccaactat aaaagcccct aacctgacct atttgactac
    25921 taacagcaaa aaagcagctt aaaaacacca atcagacgcc accaaggact cttgatcagc
    25981 gcagctcgca cagacacctg aaaaatgaca gacaagcctc ttaaaagcac ctcagcaagc
    26041 tgagccaacc cttcacagaa tagacaaaca acaagagcta agtcaagacc tcaagctagc
    26101 agattacagg cagagacgct tgcaaggctt acccagcaaa aagcaacaga ctgataaagg
    26161 attcacacca cacagccaca agtcaagcag ctagcccaaa caaagcactg ctcaccaaat
    26221 cctactatgc tttctggtag cccttatcca ttcaaaatcg tatccaaggc ttcttgatat
    26281 tgcttgtctc gcaattctct gatcacctgt gataaatact ctgcctgata catcacaaag
    26341 tcaaaattga aatccagaat tttggtgttc tcattcaatg acagcctctc ctcgataaaa
    26401 gcagtcatct cagctgttgt cacaatcaag tcaaaatcag ttctccaagg caattcagcc
    26461 tctgacaaaa tattaaaacg atagaccttt gcaacacaag gactcacctg ttgcatgacc
    26521 aagctatata aaatatcaat gtttttcttg ttgatttcga tcactgctat ggctaaaggt
    26581 ggcagacctt ctctaacaag ctgttccagt cgcgtgcaaa gcaaatgcaa attagagcct
    26641 gtcagccgac caacaccaga aacccgctct gcccagctat taatcatcag ctcgatacga
    26701 ttggccaaga gcttactgcc ttgatattcc tccgcataat aatatttttg cgggataaag
    26761 agcgacaaat caaacaaggt cttacgaaaa taaggaatca aggtctgaat acaagccttg
    26821 tcaaaggcga tatagtggcc aaacaattga cgcagctcac ccagcagctc ttggtaagca
    26881 ggatcctcct gaatgatcgt caataaggcc gaagaatcct cctcagacca ttgtgtgatc
    26941 gaaaaagagt tgttaaccgt caaataaacg agaaaaatat aatcaatctc gctactggga
    27001 aagtccatat caagcaacaa tttcccctca cgcttgaaaa agtcctccaa atacccataa
    27061 agcgccaaag actttaagcg tttaaaaatc ccctcctgag gaatcgcaac gtcaaactct
    27121 ccacgcttcc aagatagcga caagagcaca tcaaaaaagc gaaacttctt atccagtaac
    27181 gggtgaggcg tttgttgctt tttgatcgaa aagataaagt catgcacaat atccagatca
    27241 tggtcagtca gctcatagat gacaatcccg tacttatcat gcaataaagc aatcaaatag
    27301 cggatacgcc actcctcacc aacaacacta ttatcctcta aggccaagcc gcactcctca
    27361 acaaagggct tcatgtgctg aatcagccga taagctgacg gtgtggaaat aaaatgctcc
    27421 ctagcaaagc ctgagacaga tttgacctta tagcaaggtg ccttgatcaa gagaaattta
    27481 agaatgtgca gccgtaccga ttggcggtaa atcgtcttca aaaacggttt gccccttttc
    27541 aaaacggtgc agcggacaat ggtgctatcc cactcaaagg cgatatctcc ttggaaaagc
    27601 tcctctaatt ggtggatata gcgctttatg ttagctaggc taaagcccgt cttttgctga
    27661 atggcgtgga aactgatcct ttttttacca agtagtatgg tcagcagcaa agcctgatga
    27721 ttaatcactg gttccaaata ctcttcaagc aaaacacttt ctcctcctta aaccatttcg
    27781 ttagcgtcat tatcataaca atttttacca aaaaagtgat gaaaaatatt taatatcagg
    27841 acgatttttc tgatagcctt tattataaca caaaagctca aggcaggtaa aacgataaag
    27901 aaatcaactt aaaactatga cacagtctca tctcatatga tatagttatt caggtttcct
    27961 aatggaaaac atattaacaa cttaataatg gagagaagaa agttgaaaac aaaatcattt
    28021 agaaaggtac tgacaacgtc agctacctgt attgtgctgg caacaagctt tgccggagga
    28081 accctaagag tctgggcaga gcagctttat tatgggtgga atgatggaac gagacaaagt
    28141 tcgccatatt ttttgtacgt atcgcctaaa aatgctccaa agcgtgaatt aaaagacgag
    28201 tatgttgttt attgctttaa caaaaaattg tattggccag atcaatggga atctatatac
    28261 agcaatttta atgacatcag atctccatat aacgatttac ctgtatatga gaaaaaacta
    28321 ggatatgatg gtatatttaa acaatatgct ccagattaca aaaaagatat tagtgatatc
    28381 gcaagtgctt tggtggcagt tttaagtaat ggatacccca ctaacaagtc acaactatca
    28441 actagctacc atttaaataa tgattcttct agaaaagtta ctcaattagc catttggtat
    28501 tttagtgata gtttaacaaa agaatacctt aaagatacgg gtggttataa cttaaacgat
    28561 atggaaaaaa aagctttaga ttttttaatc agtaaaggag aggattctaa gcttaaatca
    28621 gagcagagta attactcatt ggatatttat gtttatcaaa gtggcgggca tgaccatatg
    28681 aaagattacc aaaatcttct cggctctacc ttaattccta aagaaccgct aaagcctcag
    28741 ctaggtggtt ttagtggaca taatggaaat ggattaagcg gccttgaagg aggatcatca
    28801 ggttcacaag aaactaatga agatggtaag aaaggactta taggtttcca tggaggactc
    28861 tcaggaagcg agggcaaacg agatcctttc caggattgaa gggtgaggct ggtgcacctg
    28921 atacacctca aaagcctaat gacccattgc aaagtcttga aggtggtaac tctcctatcg
    28981 tagaacaaaa ctatggtagt actgagggat atcatggtca atctggcatt cttgaggaaa
    29041 ccgaagacac taacccacct ggtatcattt taggtggctc aggaaatgtc gaaacgagat
    29101 cctcatctga tggggcttgg cggtggtcta gctggcgaat caggagaaac gacacctaaa
    29161 ccaggacaga ctggtggtca tggaccaatc atcgagacaa cagaggacac acaaaaaggc
    29221 atgtctgggc aatctggcgg cactatcgag tcagaaaaca ccaaaaagcc tgaggtcatg
    29281 attggtgggc agggacaaac catcgaaaca acagaggaca cacaaaaagg catgtctggg
    29341 caatctggcg gtactatcga gtcagaagac actaaaaaac ctgaggtcat gattggtggg
    29401 cagggacaaa ccatcgaaac aacagaggac acacaaaaag gcatgtctgg gcaatctggc
    29461 ggtactatcg agtcagaaga cactaaaaaa cctgaggtca tgattggcgg tcagggacaa
    29521 atcatcgact tctctgaaaa cacgcaatca ggtatgtctg gacagtctgg agacactacg
    29581 gtcattgagg ataccaagaa gtctgagata atcattggtg ggcaaggaca aatcatcgac
    29641 ttctctgagg atactcagcc gggtatgtct gggcaatctg gaggcaccac aattgtcgaa
    29701 gacaccaaga agccgacacc taagcctaaa cctgcacctg cgccaattgt taatgacgaa
    29761 aaacctaaca aaggcactca gctcccacag acaaatgata tgaagcaact caccctaagc
    29821 atcatcggtg caatgtcaat gctgcttgtc ctatgtctgt ctctattcaa gcgaccatct
    29881 aaaaaagact aagcaacact gacaagtgat cattattgta cggacgttta caggcgggct
    29941 ttctgccctc ttaaaacacc gtacaacaac aaaacggtct aaatagaaat atccctcaag
    30001 ggttagacaa tcgctctagc ccttggggct ttttttgata cttataatag aagagagcaa
    30061 gcagtgacac tttctttttg ccctatatct gctaacacta gcggtatgtg cagttaccat
    30121 aggctatcaa ctcgtcgtgc aactctagag aaaagctgat acaaaaaaca agcaccagcc
    30181 ttgctgctga tgcttgctcc ggacttactg ataagccttt gtgatgtcct agctttataa
    30241 ccatatgcct attacctaaa ggtctagtct cctaatggtg ggctggctgg taaaagcaag
    30301 gagaaacagc tcccctttcc aagctggctc tcaacagcaa tatccccacc tagttggcga
    30361 gctaactgcc tagcaataga gagccccagc ccatgaccac cagtcttcat attgcgagag
    30421 gcctcaacac gatacaggcg cttgaaaatc aaaggcaggt cctctttttt gatcccttgc
    30481 ccctgatcaa taacatcaat gcgaatggac tgctcctgtt gataagcatg aatcgtcaaa
    30541 gccgtattag cctttgaata tttaagcgca ttgctgacta aattcagcat aatccgagac
    30601 aaagcatcat atcggctgct gatcttaacc acctcttttg ccacctcaat atgaacggag
    30661 cgtttttcct gctctaaggt caattgaaat tcggatagca tgtcaatcaa tagcttttca
    30721 agatagatga tttgaagctg ctgcttgtcg tcttgctttt gatcatttaa gctgaccata
    30781 tgcaattctt caactaattg attcaaacgg ttggtctgtc gtgagatggt gtttagatag
    30841 tgcctttcct cttcccttgg aataacgcca tctaaaatcc cctctacagt tgcttgaata
    30901 gaggtcaagg gtgtcttaat atcgtgcgac agctgagcaa tcatcatgga tttctcatgc
    30961 tcactctcac tcaatgactc aaagctgacc tttagctctg aggacatctg attaaaggct
    31021 tcctctagat ctttaaactc caaaggacac ttgatgagct gaccactatc aaagtttctt
    31081 tcagaaatag cctgtatctt tttctttagc cttttaagcg atgaaaaaac attactcaaa
    31141 aggatcatat tcacaattcc tccggctact gaagcaatta gagctattac taaaatatat
    31201 gaaatatcct caatggtaat gagcatttgg tttaacccaa caatcaggcc tgcaatagta
    31261 atcagcatag acattaaata gccaatgaca atgtacgttc ttaatcgcat gctacccctc
    31321 taatttataa cctagtcccc aaaccgtttt aatggttggt gtttgctcgg tactgtattt
    31381 tgccaagtca ttgcgtaggg aatgaatgtg aacatttaag gtattggtat catctaaata
    31441 ctcctcctcc ca
//
LOCUS       DARYUW010000021        30142 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYUW010000021 DARYUW010000000
VERSION     DARYUW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30142
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TVW11_000853"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TVW11_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1364965.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TVW11_000854"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TVW11_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TVW11_000855"
     CDS             1286..2599
                     /locus_tag="TVW11_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1364966.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGCNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TVW11_000856"
     CDS             2700..3587
                     /locus_tag="TVW11_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1364967.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TVW11_000857"
     CDS             3600..4430
                     /locus_tag="TVW11_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1364968.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TVW11_000858"
     CDS             4446..4901
                     /locus_tag="TVW11_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1364969.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TVW11_000859"
     CDS             4926..5576
                     /locus_tag="TVW11_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1364970.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TVW11_000860"
     CDS             5605..6525
                     /locus_tag="TVW11_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1364971.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TVW11_000861"
     CDS             6540..7424
                     /locus_tag="TVW11_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1364972.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TVW11_000862"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TVW11_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TVW11_000863"
     CDS             complement(7738..8562)
                     /locus_tag="TVW11_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1364973.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TVW11_000864"
     CDS             8791..9564
                     /locus_tag="TVW11_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1364974.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TVW11_000865"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TVW11_000865"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1364975.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TVW11_000866"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TVW11_000866"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1364976.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TVW11_000867"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TVW11_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1364977.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TVW11_000868"
     CDS             12390..13052
                     /locus_tag="TVW11_000868"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1364978.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TVW11_000869"
     CDS             13045..13677
                     /locus_tag="TVW11_000869"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1364979.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TVW11_000870"
     CDS             13679..14950
                     /locus_tag="TVW11_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1364980.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TVW11_000871"
     CDS             14940..15878
                     /locus_tag="TVW11_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1364981.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TVW11_000872"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TVW11_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1364982.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TVW11_000873"
     CDS             16830..19334
                     /locus_tag="TVW11_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1364983.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TVW11_000874"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TVW11_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1364984.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TVW11_000875"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TVW11_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1364985.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TVW11_000876"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TVW11_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1364986.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23059..23277
                     /locus_tag="TVW11_000877"
     CDS             23059..23277
                     /locus_tag="TVW11_000877"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364987.1"
                     /translation="MDSIPAFLMCYNRWAVQQLIKAMTEKSSPIRHKRLGKGLKKALL
                     TTLSDTFGCPKKLFAVSILMEKQSFENG"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TVW11_000878"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TVW11_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1364988.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TVW11_000879"
     CDS             24977..25831
                     /locus_tag="TVW11_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1364989.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TVW11_000880"
     CDS             26041..27237
                     /locus_tag="TVW11_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1364990.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TVW11_000881"
     CDS             27660..28181
                     /locus_tag="TVW11_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1364991.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TVW11_000882"
     CDS             28257..28628
                     /locus_tag="TVW11_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1364992.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TVW11_000883"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TVW11_000883"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1364993.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
BASE COUNT         8644 a         5783 c         7060 g         8655 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata agagctaatg gggttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct gcaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcaca tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctaca aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa at
//
LOCUS       DARYUW010000022        29600 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYUW010000022 DARYUW010000000
VERSION     DARYUW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29600
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(103..1170)
                     /locus_tag="TVW11_000884"
     CDS             complement(103..1170)
                     /locus_tag="TVW11_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1364994.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(1297..1572)
                     /locus_tag="TVW11_000885"
     CDS             complement(1297..1572)
                     /locus_tag="TVW11_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1364995.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(1562..1780)
                     /locus_tag="TVW11_000886"
     CDS             complement(1562..1780)
                     /locus_tag="TVW11_000886"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1364996.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(1796..2317)
                     /locus_tag="TVW11_000887"
                     /pseudo
     CDS             complement(1796..2317)
                     /locus_tag="TVW11_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            2706..2912
                     /locus_tag="TVW11_000888"
     CDS             2706..2912
                     /locus_tag="TVW11_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1364997.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
     gene            2962..3117
                     /locus_tag="TVW11_000889"
     CDS             2962..3117
                     /locus_tag="TVW11_000889"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364998.1"
                     /translation="MVTKFSEEIKIVRTKSSVYVNSVLDVADKKDPASVAAVAELLKA
                     YKSLTEL"
     gene            complement(3118..3321)
                     /locus_tag="TVW11_000890"
     CDS             complement(3118..3321)
                     /locus_tag="TVW11_000890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1364999.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            3381..3842
                     /locus_tag="TVW11_000891"
     CDS             3381..3842
                     /locus_tag="TVW11_000891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365000.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGSRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            3983..4711
                     /locus_tag="TVW11_000892"
     CDS             3983..4711
                     /locus_tag="TVW11_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1365001.1"
                     /translation="MNELINITVNDNHEPVVSGRDLYKVLEIKTQYTKWLERMSEYGF
                     VENEDFMAISQKRLTAQGNQTEYTDHILKLDMAKEIAMLQRNEKSKQVRKYFIQIEKD
                     FNSPEKIMARALLMADKKVHKLEAQIEADRPKVLFANAVSASKSSCLIGELAKILKQN
                     GINIGQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNV
                     TPKVTGKGQQYFINKFLNQEYLPV"
     gene            4745..4894
                     /locus_tag="TVW11_000893"
     CDS             4745..4894
                     /locus_tag="TVW11_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365002.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(4891..5091)
                     /locus_tag="TVW11_000894"
     CDS             complement(4891..5091)
                     /locus_tag="TVW11_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1365003.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            5202..5486
                     /locus_tag="TVW11_000895"
     CDS             5202..5486
                     /locus_tag="TVW11_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1365004.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            5483..5629
                     /locus_tag="TVW11_000896"
     CDS             5483..5629
                     /locus_tag="TVW11_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365005.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            5833..6078
                     /locus_tag="TVW11_000897"
     CDS             5833..6078
                     /locus_tag="TVW11_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1365006.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            6240..6623
                     /locus_tag="TVW11_000898"
     CDS             6240..6623
                     /locus_tag="TVW11_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1365007.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            6604..6837
                     /locus_tag="TVW11_000899"
     CDS             6604..6837
                     /locus_tag="TVW11_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365008.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            6834..6974
                     /locus_tag="TVW11_000900"
     CDS             6834..6974
                     /locus_tag="TVW11_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365009.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            6983..7189
                     /locus_tag="TVW11_000901"
     CDS             6983..7189
                     /locus_tag="TVW11_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365010.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            7324..8052
                     /locus_tag="TVW11_000902"
                     /pseudo
     CDS             7324..8052
                     /locus_tag="TVW11_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            8229..9440
                     /locus_tag="TVW11_000903"
     CDS             8229..9440
                     /locus_tag="TVW11_000903"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1365011.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            9433..10269
                     /locus_tag="TVW11_000904"
     CDS             9433..10269
                     /locus_tag="TVW11_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1365012.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            10454..10795
                     /locus_tag="TVW11_000905"
     CDS             10454..10795
                     /locus_tag="TVW11_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365013.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
     gene            10792..11304
                     /locus_tag="TVW11_000906"
     CDS             10792..11304
                     /locus_tag="TVW11_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365014.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASKLRLIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            11526..11753
                     /locus_tag="TVW11_000907"
     CDS             11526..11753
                     /locus_tag="TVW11_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365015.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            11757..12179
                     /locus_tag="TVW11_000908"
     CDS             11757..12179
                     /locus_tag="TVW11_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1365016.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            12347..12577
                     /locus_tag="TVW11_000909"
     CDS             12347..12577
                     /locus_tag="TVW11_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365017.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            12954..13388
                     /locus_tag="TVW11_000910"
     CDS             12954..13388
                     /locus_tag="TVW11_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1365018.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            13926..14000
                     /locus_tag="TVW11_000911"
     tRNA            13926..14000
                     /locus_tag="TVW11_000911"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            14159..14650
                     /locus_tag="TVW11_000912"
     CDS             14159..14650
                     /locus_tag="TVW11_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1365019.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            14685..15938
                     /locus_tag="TVW11_000913"
     CDS             14685..15938
                     /locus_tag="TVW11_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1365020.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            15948..17447
                     /locus_tag="TVW11_000914"
     CDS             15948..17447
                     /locus_tag="TVW11_000914"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1365021.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            17447..19057
                     /locus_tag="TVW11_000915"
     CDS             17447..19057
                     /locus_tag="TVW11_000915"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365022.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            19023..19244
                     /locus_tag="TVW11_000916"
     CDS             19023..19244
                     /locus_tag="TVW11_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365023.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            19296..19580
                     /locus_tag="TVW11_000917"
     CDS             19296..19580
                     /locus_tag="TVW11_000917"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365024.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            19666..19905
                     /locus_tag="TVW11_000918"
     CDS             19666..19905
                     /locus_tag="TVW11_000918"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365025.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            19890..20492
                     /locus_tag="TVW11_000919"
     CDS             19890..20492
                     /locus_tag="TVW11_000919"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365026.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            20494..21366
                     /locus_tag="TVW11_000920"
     CDS             20494..21366
                     /locus_tag="TVW11_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365027.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            21377..21625
                     /locus_tag="TVW11_000921"
     CDS             21377..21625
                     /locus_tag="TVW11_000921"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365028.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            21628..22014
                     /locus_tag="TVW11_000922"
     CDS             21628..22014
                     /locus_tag="TVW11_000922"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365029.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            22008..22352
                     /locus_tag="TVW11_000923"
     CDS             22008..22352
                     /locus_tag="TVW11_000923"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365030.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            22349..22702
                     /locus_tag="TVW11_000924"
     CDS             22349..22702
                     /locus_tag="TVW11_000924"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365031.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            22705..23073
                     /locus_tag="TVW11_000925"
     CDS             22705..23073
                     /locus_tag="TVW11_000925"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365032.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            23077..23574
                     /locus_tag="TVW11_000926"
     CDS             23077..23574
                     /locus_tag="TVW11_000926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365033.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            23594..24001
                     /locus_tag="TVW11_000927"
     CDS             23594..24001
                     /locus_tag="TVW11_000927"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365034.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            24009..24626
                     /locus_tag="TVW11_000928"
     CDS             24009..24626
                     /locus_tag="TVW11_000928"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365035.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            24627..27074
                     /locus_tag="TVW11_000929"
     CDS             24627..27074
                     /locus_tag="TVW11_000929"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1365036.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            27078..27839
                     /locus_tag="TVW11_000930"
     CDS             27078..27839
                     /locus_tag="TVW11_000930"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1365037.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            27850..>29600
                     /locus_tag="TVW11_000931"
     CDS             27850..>29600
                     /locus_tag="TVW11_000931"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365038.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDPNRTKTYDQDYIELEANDGGFRRGETYTISFSQTCELLKKVAITL
                     TQANNKGVKLVLTPTKA"
BASE COUNT         9848 a         5136 c         6479 g         8137 t
ORIGIN      
        1 tatacaaacg aatccttgat taacctcgta aaaacgttgt taaatcaagg tttttatttt
       61 ttgtggcagg ataaaaaaag agaaaaaaag aaataaagtc ggtcaaaagt cggtcaaatt
      121 tccaaaaata tcttttatgg cctgattgtt cttttctttt agcttatcta gctgatgggc
      181 atatacctta agcgtaatgt tcaaattctc atgcccaagc aactgagata tggatattag
      241 gtcaacaccc tttaagatta aaaaagatgc gtaagtatga cgtagagagt gattgcgtac
      301 aggacgacca acaatttttt taaccaatct attgcagagt gaattagaag ctccgtagag
      361 caccctattt agcttatttt cattataata attttcttta aatgctctaa gcaattttat
      421 agtttgctga tcaatgggaa tttgtctttt tgattgctcg ttttttgttt ccttaaattc
      481 ttgagttttt gagtaatcaa acgatttatt aatatctata aatcccttct caaagtctat
      541 atcgctccaa gttatcccgg tcgcttcggc gaatcgtagt ccagtcactg ctatgatgta
      601 taaagtaaaa taggaaacat actggtattt ctcactcgtt actttgatta gatttagata
      661 ttcatcttct tcaaggaaat caaattcttt tgctctagct tctttttgag attttacaat
      721 cgcaccttcg gcaaaatttg ttttgataag cccatctcta actgctacat taacagctcc
      781 ttttatttga tagtggagtt tttcgagtgt ttcttgggca tattttttgg caaattcgtt
      841 gattgttttt tggtaaaagg tatgcgttac attattaagc ttaatatcac caaaatattt
      901 tttgatgtgc ttaagatttt tagtgtaagt ttcccaagtt ttatcgacaa catgcggacg
      961 tttgtagatt ttagcccatt ccttgcaaaa atcataaagt gatatatcat caatatcttt
     1021 atttagctca gcctcgactt taatcgcagc tgcagaagcc aatgcttttg tcttaaaacc
     1081 acctttggat ttttcccttt tgttcccctg actatctgtg tagtaaatac gataagacca
     1141 cttgtcgccg cgttttctaa attttgccat tgttaattac ctcattttta tgttaaaatg
     1201 ggtacagtaa agagacctac tgcgaagcag gttttttact atacaggatt tgcctcacgc
     1261 tcagactcgc caaagtttga gagcgtgggg ctttttttaa cgtttgattt tatagactga
     1321 gcttcgatgc tctattttaa aaacttcgat gacaacttcg tcatcaataa tctcagctaa
     1381 aatacgatag tttcctaaac gataacgcca ctctcctgta cgattagctt gtaaagcttt
     1441 tccgtatctc cttgggttat ctgtgccatc aaggttagtc attatccact gatagagttg
     1501 tttagcagta gatctatcta attttttgag ttgttttttg gcttttttag taaacaatac
     1561 tttataacgc aaaacctagc tccttcgcta catcttccat gctaaatcgt gtcccatcgt
     1621 cctcagcctt agcttttctc aattcgtaca aatctttagc atcttcaatg atttccaaaa
     1681 actggtcaac tgttagattg gaggtgtcaa tgttattttc tttgatgtaa tctgcgatat
     1741 aagcatcgtc tttttcaagg tttaatgtca ttgcaatcat agtatttttc tccttctata
     1801 tttctactgg tgtaaagctg ccgacgacat catagatttt gatgtaagta tcttctgctg
     1861 gcgggtagtc gataaagata tcattgtatt ttttattgag agatactaat ctaagcccgt
     1921 cttcctctgt gtatactttt ttaaaatagg tctgtccgtt atgcacaact atacatagct
     1981 gaccggcata tgctgacatg ccccgatcta caatatagag catatctcct tgctcgtact
     2041 ttggtagcat actatcgccc cgcactccaa ttgcatagtc gtagtgaggt ggttcttcgt
     2101 cagtgtagac agtatatgtg tcatattcat ctgcttcaaa tccacgacca aagccacttg
     2161 cggctgccgc gtaagttacg ccttgaaccg aaaataattc ttcatgcgta gaaacaactt
     2221 tattttgttc ttccaattgc tccttggcaa agtcaaggac tttttcttgt ctaggttgtt
     2281 ctagttggtt gtagatggac actatttcag atgtattttt tggggcatct agcagagacg
     2341 aaaacacctc gggtctgata cctaaagctg agcaaatttt tatggcattc tcgacgttag
     2401 cattcattat tcctcgctct aatatcgagc gaaccgttga gtaaggcatg ttgttttctt
     2461 ctgcaaaaga ttttacagag ctataacgag aaagtataag atgttttaga ttttcttcat
     2521 tcatggctgc ctctctttct gatttcatta taacacacga tttttcgttt gtctaacaaa
     2581 aaaacactaa gaaatacgaa ttttagtatt gacaaacacg aaaaaaagta ttaaacttgt
     2641 atcaagctca gatgagctta actttaaaac caaaaacacg aaaaatcgtg ttagaaagga
     2701 gttatatgtt aaatattgat aaagtgcgaa aagaaaaagg cgtagcaata gtagacatgg
     2761 ctgattttct tggcgtaaga gctcaaacag taagcgataa attgcgcggg acttacgatt
     2821 ttaaatttac tgaggctttg gcgttgcaac aaaaattttt cccggagtac gatttagaat
     2881 atctttttaa caaagcagta gacactgctt aactttaaaa ccaaaaacac gaaaaatcgt
     2941 gttagaaagg agaaaatcaa tatggtgaca aaattttcag aagaaataaa aatagtaagg
     3001 acgaagtctt ctgtttatgt aaacagcgtc ttagacgttg cagataaaaa agaccccgcg
     3061 tctgttgcag cagtcgcaga gcttttaaag gcgtataagt cgttaacaga attgtaatca
     3121 actatggtga cttatatacg tgacttgatc gagattgacc aaaacgatgt attgagcgtc
     3181 tgatagtttc agttcaataa tatttggatt atcagggcac tcatttgcaa cttggcagaa
     3241 tgtgtgttgc ttaccatttg tgaacatgat tgtaatggta tcagtttcat tcgctagttg
     3301 ttcgataata tatcgtttca tacaatcacc tcctttctgc tcatattata gcagttaagg
     3361 acaactagag aaaggacact atgcaagcaa atcgaatttt ttacggaaaa gaaaaaccaa
     3421 caaacgcagt agcgggcgat tgctggttta gagataacga attaatgata ctcaaggaca
     3481 attgggaagc tagcgtaaac aacttaaaga gccctaaagt tatcggagag atagaaatag
     3541 acctagagca gcatgatgta ctgctgacag ccagagggag ccgtcctcca ctattaatga
     3601 ttgatgggat aatgttgggc ggagtatcta aggtaataat tataaatgag ttatccgagt
     3661 cttgcgcaat tgtctctctt aatgagtata tcaaggagaa tttgttccct tttgacgatt
     3721 ttgaatcact tcaaaggtta tttcaaaagg gccatcagaa attatccgta cgggaacttt
     3781 gcttagaaaa acgtttaggt gagcattctt atcaagacca tcgaaaaagc tgcgatgaat
     3841 agtaaaagtt ttcttaccgc tcgcaagagc tttctcgtaa tcctgagtca gtagtttaac
     3901 agagagatct aattgatagt cgtacacttt tgtttatcct ccttccacta ggataactac
     3961 attatacaac agaaaggacg ctatgaacga actaatcaac attacagtaa acgacaatca
     4021 cgagccagtt gtcagtggtc gtgatttgta caaagtgctt gaaattaaaa cacaatatac
     4081 aaaatggctt gagcgaatga gcgaatatgg tttcgttgaa aacgaagact tcatggctat
     4141 tagtcaaaaa agactaacag ctcagggcaa tcaaactgaa tatacagacc acattctaaa
     4201 actagatatg gcaaaagaaa ttgcgatgtt gcaacggaat gaaaaatcta agcaagtccg
     4261 caagtatttt attcaaatcg aaaaagactt taacagcccc gagaaaatta tggcaagggc
     4321 gttgctgatg gcggacaaga aagtgcataa attagaagct cagattgagg ctgaccgacc
     4381 caaagtacta tttgctaatg ccgtaagtgc tagcaaatca tcttgtctga ttggtgagtt
     4441 agctaaaatc ctgaaacaga atggaatcaa tattggtcag aataagctat ttcagtggct
     4501 tagaacgaac ggttatctaa ttagcagacg cggcgagtca tggaatcagc caacgcaaaa
     4561 aagtatgcag cttggattgt ttgaactcaa aaaaacagcc atcaatcact ctgacggtca
     4621 cactacaaca aatgtaaccc caaaagttac tggtaaaggc cagcagtatt ttattaataa
     4681 attccttaat caggaatatc tgccagttta gaaaggaaac aaaaccaacg aaaaggagaa
     4741 aagtatgcca gaggatttaa tcaaacaact agaagctggt tcagaatttc tagcaaagac
     4801 atgtttacat agcaagatta ttatcacggt ggatggtgtt cggcttgtgg aaacaaaaga
     4861 gttccaccca gtgagcggaa ctctactaga ttagacaata cgtgtataag tgtgtatctt
     4921 agctaatcta tgaatatttg agccaacaga cccaacaaga acagaacggt attccgtttg
     4981 gcttacattg tgataatggt aaatagaacc attattaaac tcaacttcca aagtgttatt
     5041 ttcccaacca acacttcgga cgttactaga tgaaacgtat tgacgttgca taactttttc
     5101 tcctttccgc gatgatagct ttattatagc acgcaaggag aatacaaaaa aagtccgacg
     5161 ggaatcggac tcgacaataa tatttatgag gtaattttat catggatagt agattattac
     5221 aaatgcttga tgagtttgag gcgggtctga tagaccgtaa aatcaaagtc ataggcatgc
     5281 ttaataacga aacggaaatt tatccgctag agcttaacaa aaagcaaatc agtaagatgc
     5341 tgggagttga tcctaaaaca tttgacgtaa gatttaatag ccacaaagat tttccgcgca
     5401 tcgaaacggg aggtcgggaa aaatacccac gagatttagt tattgagtgg tatagcaaaa
     5461 actgggaaag gacggggata agatgattaa aaaactattt aactttattt ttgcaaagcc
     5521 aaaagaagaa tcaaggcaac cttatcaaca accgagaggt tttctggatt ttgaaacagg
     5581 taaacgaatt gaaatagatc cgataacaag aaaggaatac ttcgtatgat gcatcaaatt
     5641 aatatatcgc ttagaaattt tgtcgagact ggagagattg acaacatctt cgacattttt
     5701 agaattttag atttctactt tcgggaggtg gtcagctgat gcagtacatt tttcaagacg
     5761 ttgagaggga gttacacgag cgttagtaat gagtttgtca acgataaaaa actttataac
     5821 aaggaaaagg gattgttgtt gaccattctt agcaatagcg atgagtggcg agtatatccg
     5881 gaggaattgg ctaaacgttg cagagatagt gttgacgctg tcagaactca gctaaaagca
     5941 cttgagaaag ctggatacat cagaagttat cggaagtcgc ttggcgggcg atatggtacc
     6001 gaaacccata gattttgctc agacacaaaa ataagtgatg aggtttttca agagctgctt
     6061 aaagaattaa attgctaatg tgcaaattgc taatgtgcaa attgctaatg tgcaaattgc
     6121 taatgtgcaa attgctaatg tgcaaattgc ctaactaata aatactaaca ctaaataaat
     6181 actaaataat aataaatact aacaaacaat aagcatcatc atcaacagca ggaggagcta
     6241 tggacgaaaa aaagcttttt gaaaattttc aactaacttt cggaagaatg atatcgccat
     6301 ttgaaataga agatattcaa aagtggattc accaggataa tatgccgatt gatgttgtta
     6361 accttgcttt aagagaagcg gtagaaaaca acaagatcaa ttggaagtat atcaacaaaa
     6421 ttttggtgga gtggcataaa gctggagata cgacgattga gaaggtcaaa gagaggttgc
     6481 agagatttga ggatagcaaa gaacaacgac atgcaactat ctcaaatgtt cctagctggt
     6541 caaatccaga ctaccaaggc ccgacatacg atgatttaaa agtaaatcca agcgaggtgt
     6601 cagatggcgc aggagatttt tgatggattt aatgccttaa tcaataaaat gtatggcaga
     6661 caatctagca tagagacctt taaccgattt gtcgagtatt gtcaaaaaag gagagaggaa
     6721 aacggggttg agcctgtatt aaatccgatc aatctttttg cattcggcgt tggaatcaca
     6781 acggaagaag ctaataaatt aagaataaaa cgctacaaac aggagaatgg attatgacaa
     6841 aacaatatcg agagacactt atctggcatc gggcaagtca caaagagcgt gagaagctgc
     6901 ttgatttcgg gctagttgat aaatcacagt acatgacact attacgccaa ttgcgcaaga
     6961 aatatgcgat ttaggaggaa atatgacacc agaacaagtg gaaaaagcaa aaatcagagc
     7021 taaacgagaa cttgaaacgt ttagcatcta ccttgaccag gcgattgtcg aatacggaag
     7081 tacgctaagt ccacaagaag tctttttagc ggcagggttt gcctaccttg gtgcaggtca
     7141 gactgacata catgcggcca tcgaggggtt atatgagcaa atccaatgat tttaatttta
     7201 gcgatgactg ggaaagcaac tatttcgagg tccaagcttt gctagggcaa gagatagaca
     7261 agctccaaaa cagggtcata gcgctaagcc aggaaaacaa tagattaaaa gcgaggaaat
     7321 gaaatggcaa gtgaaattgt aacaattcaa aaagatatca ctgatatcgt taattcaaaa
     7381 attagtatgc ttcagaacga aggtcttgta atagcgccaa actatgctcc agcaaatgct
     7441 ttgaagtcag cattctttaa aattttaaaa accaaagaca gaaataagag gcctgctctt
     7501 gaagcctgca caaaggactc aattgcgaac tcgctccttg aaatggtcac ccaaggatta
     7561 tcacctgcaa aaaatcaatg ctattttatc gtttacggga atgagctcca actgcaaaga
     7621 tcatatttcg gaacaatggc agttttattg cagcagaaaa aaattaaatc aattaagtca
     7681 gaagttattt atgaaggtga cgattttgag cttgaaattg tagatggtga aaagaaattc
     7741 aaaaagcatg atactcattg gaaaaatcaa gacaatccaa ttgaaggggc ttattgcatt
     7801 attgaggata tagatggtaa cactaagcta acactgatga caaaaaaaga gattgataaa
     7861 gcgtggtcta agacaaagac tggtggaggg acacaaaaag aattccctca ggaaatggcc
     7921 aaaaaaacag ttatcaacag agctgctaag ttttttatca atatcagtga tgacagtgac
     7981 attttggcag attctattaa caagaccacc gcagatgaat atattgacga tcgtcaagta
     8041 aaagatgtaa cggaaacaca gtcacctgca cagacactac tcgataacat gaagcatgac
     8101 gaggaaatga gcaaaatcga aacgatgcaa aatgaacaat tgatgcatga tccagaaaca
     8161 ggagaaatca ttgatgcaga ggttgttgag gcggacctaa aggaatctga tatggaggag
     8221 ccattctaat gagcgaaaat ttaacacttt ttgaaaattt aaatgacatt aaaccagccg
     8281 aacccgctga gctgagtttt gattttgagt ttactccagc cgaaatcaaa atcaaaggga
     8341 aagagaagct cgaagagatt ttagcagcct acgctaaaaa atacgatggc tacacagtga
     8401 cagccgaaac ctttgaagac gatgcaaagg ttagagcaaa actcaatact ttgcagaaag
     8461 atattaataa ctctgtaaaa acaaaactcg cagaatacaa taaccctctt gatgatgtta
     8521 agcagtgggt taactcaatt attgagccaa ttaaaaaaat tacaaaaacg attgatgagg
     8581 gtgttaaaca ctttgaagaa atcgaacgtc agaagcgtgc aaatacaatc aaagaaacct
     8641 ttgaggctgc tattgctgaa acaggtgctg atattgatat ccgcttgttc gaatctaact
     8701 ttgacgatat gtcggctaaa ggatatttta tggctgacaa cgtccgcgtc aataccgcta
     8761 ccaaaaaggc cattaacaaa ttggttgctg aagaagtagc aaaaaaacag gaacatgagc
     8821 aggcgcttat ccaaatttca gaagctgctg ccaaagcgga ttttggacca gctatctata
     8881 tcaaacgatt tgaaaatggc gcacaactgg cagatatctt acaagcaatc gctgacgata
     8941 aactgcttgc tgacaaggtg cgcgaagaag aaaaacgcaa agcagaacta tctaagcgag
     9001 tagaagaaat gacagccctg gcacaacgtg aagggttgca accaggcaaa tatgtaaaat
     9061 tgcttgaaga tggcaagtct gctttagtcg tttttgaaac tctgatggac gattctaaaa
     9121 aaatgcaggc caagatagca caaaaaaacg cagaagcgca tcagcaacaa atagaacaga
     9181 ccgaatatat gtctgaggcc tcaaattcgg gggtaaacga gcttgaaaca gacaaggtga
     9241 taaataatat catcaaacaa gaaaatgcct tagaagccaa aatagaaccg aataagagcg
     9301 tcacaaaatg gcaaggtgat tttaaaataa ctttcccgga ttcagaaaca gctaaactat
     9361 ttggcgggca aggcggatta tacgaaaagc atggcgtgat tgttgaaaaa ttaggtgaat
     9421 gggtgaagat taatgactaa attaaccgaa gaaaattatt atcaagaccg agaatggttg
     9481 tctaactcaa gatttaaggc tttccttgat tgtgaggcta aagctttagc tgtcgaaaac
     9541 aacgagtggg aagataccag agatgagaca ccgcttttgg ttggtaacta ccttcacagc
     9601 tatttcgaaa gtcctgaagc tcatgagaaa ttcaaagccg agaatggagc taagatgatt
     9661 tccagtcgtg gagttacaaa aggggaactc aaaaaagagt acaaagtagc gcaaaacatg
     9721 attgaaacgc tagaaactga tgagatattt aatctcatgt accatggcca atctggtgat
     9781 aatgttttga aagaaatgat catatacggg gaaatcttag gcataaaagt taaaggaaaa
     9841 gttgattcaa tcaatttaac aaaaggttat ttttgtgact taaaaacgat gaaaagcata
     9901 cacagcgacg aatggagtaa tgacttgcgt aagcgtgtac ctggtgtagc agctaacatt
     9961 atcgggttta aataccatat ccagatgggg ctctatcaag aattactcag acagatgact
    10021 ggaaaaacgc ttcaaccgct aatcattgca atcagtaaag agaatgtacc agataaggaa
    10081 ctcatcgaac ttggccaaac gtggctagat gaagggttgc aactttttga aaacaatgtg
    10141 gagcatgtgc acgaagtcat cattggtaaa gctgaagcta agtcgtgtgg acgttgtgat
    10201 tattgtcgaa gtcagaaaaa gcttaatagg gtggttgatc tcgatgattt gattgcagga
    10261 attttttagg agatcttatt gtattgcaaa gtgatgctcg gcctttgcag caacaaatat
    10321 tttccgagcg agaaaggaaa attgcaatat cgtcaagtta acaggattga tgatataaag
    10381 agttgctaca ctcgtccttg ctaatgctca cacacaattt tagggcgagt gtggatttta
    10441 aaaaggtgaa aatatggaac aaatcaaaat tacaggaact gacacaatat taattttaga
    10501 tagagtagat agggcctttg tcattgaggg taatctagct gaaagatggc gttttactag
    10561 caagtttata aagattgacg atgagctatc gctggacgag gacggcgaat tgtttgagat
    10621 agtttatgac ttaatgctag aagcaaaacc tcacaacgtg attaatctaa catcatcata
    10681 ttttgctaaa gaacataaga aagacacaga tgaaatcata aaagtatttg cttttatcga
    10741 agataacaag aagaatattt ttgaaaccct tggcattcgc ggggtgcttg aatgagcaat
    10801 ctagtattat cgctagacat ctcaacatct ggtacaggtt gggccttatt taaaggctca
    10861 gaccttatcc agagcggtgt cttaaaacat aagagcgact cttattttga acgtggacgc
    10921 tatatggcta gcaaattaag gttgatccag tcacgagcat taaaaaaata cgattgctcc
    10981 tttagcacaa tcgcagtcga aaaaaactcg gttatgggtc caaatcaaca atccatgctt
    11041 aaaatcggca ttgtaactgg tatcatctta ggacgattga tagctgataa tgtcgtattt
    11101 atcaatgtct caacttggcg aaagcactgg aagtttagct acaaagaccg ctcaaaaaaa
    11161 gcaatgaaag cacagtcaaa ggctaaggct gctgaaaact ttggcaaaat agtcaaagat
    11221 gatgaggcag atgccgtctt gattggtgca tactatgtca atcaaggcta tcttgatgga
    11281 ttggagacac atgactacta ctaaaaaaca cgttgtgagg atttacaaca aaggtattac
    11341 agcaacccac gcagttactg ataaaaattt atttacagag tatacatttg cgacgcagca
    11401 agatgccgag aattatatca gagacttaga gctaaacgga tctaagtgtg ccctttgagt
    11461 attatgagag gagatttgca aaatgataga caccgataca cttgcagcag tacgggaggc
    11521 tgatcatgac taaaaacgac tttttaacag gttttgtact tatactttta gctgcttgca
    11581 tttttgcagc aggatttgtg attggatctg actgtagtag cgagcactac gagcaacaaa
    11641 tgacaggctt gcgtatgcag cttgttaaca cgcagcagca gcttaagcgt gcgagtgagg
    11701 atagagcaag gcggactaaa aggattgcgg atctgaccgg gaatggagga tagggtatga
    11761 tcgacgaaat cgaactcgac ctacaaaaac cagaaatccc acagtttgtc gctgactaca
    11821 tagatgatat gcacaaaaac gcacgtacat tgagatacgc ttttaaatac atggaaagta
    11881 acataaaaat gcacaaatgg tgtgtttttg aaaggcaaga aacgtttgtt aatgcttttt
    11941 tatacggcta cacaataaaa aaagaaaagc tgtatattgt tgagatccct aatcctaata
    12001 gtggcataga acacaaacat attgcactag caaggttagc gaatggaaaa cttggatttt
    12061 cagagatcat agatactgat ttttattcaa gagaagatgt ccgactcacc gagtcagaaa
    12121 tccgcaaaga ttttgattgg gcatggagag aggggtttgc taaagaggtg acggaatgag
    12181 cagagataaa accagaatca ggaacattgt gaagtccatg aaacagttag gtgctagcga
    12241 agaagagaca gacgaataca tgtatctatg cgtgtttaaa aagcctcacg tcatagctca
    12301 aatccgtaaa aaggctaaga ttttcagagg cgaagggtgg taacagatgg catatttacg
    12361 agaagaaaga gaaacagtta ttcattacga cgaattggat gactgctgga cttttgaaac
    12421 taacgtccgt aggcatatta cgaaaataga aaaacgcatc gaactgtacg agattctctc
    12481 agaggaattc gatgaccgag gaaggcgtat ctatatctgt gcgaaaatga agacaggaac
    12541 tgtcagtccc tttgcgaaac caccaagaag gaaatagcta tagaatcgat tttaagcttc
    12601 aaaaacatgg caagaacgca cttctgggaa cgtgaaacac ctagctaata taaatgtacc
    12661 ctagaacaat ttaaatcgaa aaaatgatta gctacatagg ttttaatcgg cttatgtggc
    12721 atagaccgaa attaaacaca gaaggatgtg atgacaatct ccttacaccc aaaaaatcta
    12781 acactggtta tcggtcacca gctattatcc aaggcgctaa tactgacatc gtgtgcctga
    12841 gctggcttat aaaaaacgaa agagagggct tttctccaca caaaaagacg tccatgcgaa
    12901 cgcctccttg gttatatctg ttaacaccat tataccacac tgagggggct ttcatgacgt
    12961 tttttcctga gattgatatc caaaaaacaa aatccaatgc caagcgtaaa ttgaaagagt
    13021 atccacgctg gcggcggata gctaacgatg tagatactca aaaagttaca gctacttact
    13081 catttgagcc aaggcaacct catggagtcc atagcaagcc tgtagagagg ttagcactta
    13141 atcgtgtgtc agcggagcag gagttagatg cgattgagca agctgtcagc atgatactag
    13201 agccagagag gcgcaggatt ttgtacgata aatacttatc accttataaa aaagcggaca
    13261 aggttattta tacagaattg tgtatgtcag agagctttta ttatgatacg ctcgatatcg
    13321 ctttattagc ttttgcagag ctatatagag aggggtctct gattgtcgag caaggagttt
    13381 ttagctagtt tttatacagt aatataatag tttttgtaca aaatagcgtg ttaatatagt
    13441 atcatagcaa aataacaaaa agagataacc attttaccaa ttgactattt atttagtcgc
    13501 caactttaac tacgatcaaa cttgttattt tgaaggtaca tgggacgtgc aggttcgaat
    13561 cctgccgtct caataccagc tatttccaaa atggaaacag ttggaaaaga caaacccccc
    13621 attcctttaa aggcagatac gttctgatat ggggcttttt atgattaact gcaagtaaaa
    13681 caagggtcgc aaccttgctt gtggttagta gacctagtgg tcgtttatgc acgttcgatt
    13741 cgtgcaaggt ctgttgggtt gattgcaata atccttttgt ggacgcacaa caaaaatgtg
    13801 atgtaagtca cggctaaggt ttgggcggcg atagaataga tgcgcaacta tcgttgggtc
    13861 acgtctcaga gtttgcatag ttaatattaa ccgatgggca caccctgcgt cagtgggttg
    13921 tttatggata gcttagcaaa ggggttaatg cgaccaactg tttagtttgg taggcgtgag
    13981 ttcgaatctc acactattct ttcaggaaca tgaaccgtga ttggaaaacg gtagaggtag
    14041 cgccttgata attggattgt cgacggtctg attatatgtg tcggttcaat tccgactgtt
    14101 cctgttctag tcaccaattg tggtggcttt ttattatgtc acgaggaggt gatggaaaat
    14161 tgctaagtta actataaaac aacaaaaatt tattgatgag tacatcatct gtggaaatgc
    14221 gacagaagcc gctcttaagg cgggttatag caaaaaaacg gctgggcaaa tcggtgagca
    14281 gaacttgaaa aaacttgaaa taaaatctgc catcaacgaa cggctaaaac aactcgaaag
    14341 cagtaaaata gctagtgcaa tcgagatcct acaagttctt actgccgttc ttcggcagga
    14401 tttgacggag gaggttgtta cccttaatcc tgtaacaggt gagtacgtta ctatgcagaa
    14461 aaaacctagc atcgcagaag tcataaaagc tgctggtgag ttattgaaac gttatcctat
    14521 ccaagaacaa attgaaaaaa tcaagcaaga aaacgagttg ttacgcctta aaattgaaac
    14581 cgtcaaaggc gccaagcctg atacccattt gatggaaaaa ctgctggagg taatcgaaga
    14641 tggcggttag gataaaaaag ttatccacaa aacaaaaaga catcattaga cgccctttta
    14701 actacgaatt agaggtcaat gagggaacac ccagaagtgg aaagaccacc gctgggcatt
    14761 ttcgttatgc taggtatctg attgagtcag aagatgaaaa tcatcttgtg actgcttata
    14821 atcaagaaca agcttatcgt ttgtttattg atggagacgg tacagggctg atgcacatct
    14881 ttgacgggaa ctgcgaaatc aaacatgatg agcgaggaga tcacctgctt gtaacaacac
    14941 caaaaggtaa taaaagggtt tattacaagg gtggaggtaa agttaactca gtcggtgcta
    15001 ttacaggtat gtctctaggc tcagtggtct tttgtgagat taatctactg catatggatt
    15061 ttatccagga gtgttttagg cgtacctggg cggctaaact gcgttatcac ttagcagacc
    15121 ttaaccctcc tgcgccacag caccctgtta ttaaagacgt ttttgacgtc caaaatacca
    15181 gatggacgca ttggaccatg gacgataatc caatattaac tgcggagcgc aagcaaaaca
    15241 ttatcaatag cctcaaaaaa aatccttatc tttataaacg agatgtactc gggcagcggg
    15301 tgatgcctca aggtgttatt tatggtcttt ttgacatgga aaaaaatgtt ctagacactt
    15361 tgattggcga gccagtggag atgtatttct gtgcagatgg tgggcaatct gatgccacat
    15421 ctatgtcttg caacatcgta acaagagtta gagataatgg caagataagt tttaggctta
    15481 atcggacagc gcactactat catagtggag cagatactgg tcaggtcaaa gccatgtcaa
    15541 catacgccag agaacttaag gctttcattg actggtgtgt taaaaaatac caacttcggt
    15601 actctgatgt ctttattgac cctgcgtgta aggctttgcg cgaggaatta catgccattg
    15661 gtattctgac gactggagcg ccgaacaacg ctcacgacgt aaacagtaag gcgaaaggta
    15721 tcgaagttgg gatagaacgt ggccagactt tgatttcaga cggtgatttt tatctagtaa
    15781 atcacaaaga ggaaaaatat gatcattatc atttcctgaa ggaattaggg ctttatagcc
    15841 gcgatgataa aggcaaacca atagacgcaa acaaccactc aatggacgaa tttaggtact
    15901 cggtcaatgt ttttgtggga cgatacaaaa tgaaatagga ggtagtcatg tttagaaacc
    15961 tctggactaa aataaaaggg gtgatgcaaa aaatgggatt gataaaaggt ttgaaagatt
    16021 tgaacctgca ccgcgaaatt gaactgtctg ataagcatta tgatagtatc caaatttgga
    16081 aagagttgta tcaaggctat cacgataaaa tacacgatta ctatgagaaa tctatcttag
    16141 atggtcgtaa aaagaagaag cgtttgactt tgaatatgcc taaagttgtg acctcagagc
    16201 ttgctacatt gatttttaat gaaaaatgtg aaattaacat tggttctgaa aatgagagtt
    16261 tgacaaagct catcactgaa acgttagaga aaaataattt tactcaggag tttcaacgct
    16321 tcttagaata tagtttcgcc ttgggaggta tggcaatcaa agcatatctc aaaaaggacg
    16381 gtactatcgg tcttaatttt gtacaagcgg atagttttat tcccatttcg tgggataatg
    16441 ctgggattag cgaagccgta tttgttgata cgcagcatcg tggaaaatac aagtacacgc
    16501 atttggagtg gcatacttgg gaaagtgagt tgtatgtagt tgctcacgag ttatttagaa
    16561 ctgacaagtc aaatgatgat gttggcattc gcgtaccgat aacagagatt tatccagatt
    16621 taaaatcaca agtagtcatc gaaaaactat caagaccgct atttgtttac ctcaaaccta
    16681 attcggcaaa caacattgat ctatcaagtc cgctagggat ttcaatctat cacaattcgt
    16741 ttgatacctt gcgagcgatt gatattgcct acgatagctt tgagcgtgag tttcgacttg
    16801 gccgtaagag gatattggtt ccagcgactg ccattcgtac tgtagtggat agcgagggga
    16861 atttccaccg ctattttgac gcaacagacg aaacatatga ggctttccac acaggtgaag
    16921 acagcaaaat tcaagatatc aaagatatta gtgttgaatt gcgagttgat gaacatattg
    16981 cagctattaa cgcactgttg aacttactta gtatgcagat tggctttagc ccaggttctt
    17041 tcagtttcga tggagtatcg ggtgtcaaga cagccaccga ggttatctct gagaattcta
    17101 agacattccg cacgaagcaa tctcatgaaa cgatggtaga agcaacattg aaaaatcttg
    17161 ttgcgattat cgttgatttt ggggatcttt atggtttgat cgagggtgag agtaagtata
    17221 atgtaactgt aacgtttgac gactctattg cgcaggacag aacccaggac gctcagtatt
    17281 atatagggtt ggtcgcagct gggttaatca gcaagaaaaa agctatgatg aagctgttta
    17341 atctgtcaga agaagatgca gagttggaaa tccaaactat ccacgaggaa agccggacaa
    17401 caaacgatat gtcaattgat ttatttggtt tggacggtga tgcttagtgg attatgatac
    17461 tcatatccag ctgtcttttg acttaataga gctttattct gatgtcgaac gtgaattgtt
    17521 gacgtcaata ggtcgcaggt ttgcaaaaca ctatgacgaa atggtagctg gcgacatcat
    17581 ggattggcaa attaggcaat tactcgaagt tggagagctg agaaaagagc acatcgaaat
    17641 catgcgaaaa agtgcacgcg tgagtcgtga gcgtatgatt gagatgctga cggaggcagg
    17701 ttatacctcc gcaggaaggt atgaggattt ttttaaagag gcatacgtta aaggtttaat
    17761 caagctcaat ccatctgctg cagacaacag catgaggttg ttgcgagtgt taaatactta
    17821 catcaatcaa gctgaggaca cacttaatct tgtcaatacg accatgttac agtctggcca
    17881 agatactttt ttagatacag tcaatcaagt tgttgcttat gtttctacag gtatcaagac
    17941 cccacaagtt gctatgcgtg acgctctaaa aaatgctggt caaaagggcc ttacagtctt
    18001 tcgtgctaaa aatggcgccc agtggtcaac ggagacttat ctcaatatga tcactcggac
    18061 gatgaactct aacatttcta acgctatgga agatgagcgt aggcatgagt atggtgttga
    18121 ttacatcgag gtatctagcc atgctggcgc acgtccaagg tgtgctcctt atcaaggtcg
    18181 gatatattac gatggtgtcg gagatgatcc gctagagaaa tacccgcact tctcagagac
    18241 ttcttatggc gaagctgctg gattgtttgg cgttaattgc ggtcatcata aatatcctta
    18301 cgtcccaggt atgagtaaac agaccttttt cccttacagt aaaagcgaaa acgataaaac
    18361 ctatgcagag tcgcaggtac aacgtaaatt agaacgggaa gttaagcagc tgaaacggga
    18421 acgagcaatt ctaactgctg cgaaggacaa agagggggct aaattagctt ctcaacgctt
    18481 ggagaacaag tggcaggaat tgcgtcagtt tactgctcaa acaggcagaa cgagacgata
    18541 cgaccgcgag aaatcgctaa atactatttt gtctgaggac aagaaaaaag ccattgtcaa
    18601 agataatttg aaaatcagag atgagtatcg agcgattaag aaagctatcc ctgaagtagc
    18661 tcctaaaaat cttgaaacct attatgatat gcgttataat ggtggcaaga tatacgagga
    18721 tttagttagg gattacaaag actatataag atggtctaaa gctgaatttc ctactaaaaa
    18781 atcttttgaa gggcatattg atagtcactt aaaagagttt ccaggattga ctggtaaaca
    18841 atatcagaaa aaggctgctg acttattatc tagaccgata actgataata ttttaggtta
    18901 tgatacagat tctagacgtg ttaggtatga cttagaaaat aacatttttg ctttagggcg
    18961 cgttaaacaa ggtacgatta cgactatgct gaaaccaaag gaaggggttg attactttga
    19021 caatgactgg aaaagagagt ttgataatct taaatgattt agaatatgtc cattgtcctg
    19081 tttgtggaac tttgaccgag gtttatgata tttgcgatac ttgtaaatgg cagaataccg
    19141 gtgagacaaa tattgatggc ggtcctaatt atattacact tgaggaagca cgacgaaggt
    19201 gggcaaatgg tgaacctttg cgcaactttt ttaaagacca ataatacaag cactgtaaca
    19261 gtgctttttt tgtactcaaa aaaggagaga gtaaaatgaa caaacgaatt gaaaagaagc
    19321 gtcgcacaca aatgatgtta gacagaatct tgcgcattgt agaattgatg tcgcaagcaa
    19381 ctgacgacaa ctttgctatc ttggaaaagc gcttagaaaa agctgaaaaa cgtaacgaag
    19441 agcttatgga aatcatctta gtaaacgtta aagaggtaaa taaccgcttt gacgagctag
    19501 aaatctgcca gaagattgtt gaagatgatg tcgcagagct caaaaaagct aagaaaaaag
    19561 gctggttcag ccggaaataa cttaatcgtg tcgaattcga tgcggtttta ttttgccctg
    19621 ccgcatggcg ataaactagg taaaaataaa agaaagaggt ctaaaatggc tgttattatc
    19681 gtacaaacac gaggcggaga tattgaagtt cccaccccat taccagcaat gcaagctaat
    19741 aaagcgattc aaagtcaatt attcgataag gagctgactt ttttatgcgt ggataatcat
    19801 gcttttgcta aaactgaggt tttacacgtt ttggtcgaaa cagaagaaga tgaagaatta
    19861 ccacagtcaa aacataagga ggaagaaaca tgctacatgg attaaaacac cgtttgttta
    19921 aactagcccc agatactgga gcaggcggag gcgctgaagt tactagcgag actaacgctg
    19981 aagctggacg agttgagcaa acagtatcgc aacaacaagc tgatccggtt gatactgagg
    20041 caatcaaaaa tcaagcaatt aatgaggttc taagtcaact aggtgtttct tcggtagaag
    20101 atgccaaagc aaatctagct tcttggaatg aatatcaaga aggtcagaaa acagagtttc
    20161 aaaaaattca agatagtttg actgtggcta ataactcttt ggctgagcgc gacactatga
    20221 ttgctagctt acaagctcag ttagctgctg ctcaaatggg agtgcctgcg gaaaacacct
    20281 ccgatgttat cactttggcc aatagtttgg tccacgataa aacagacatc aatgcagcga
    20341 ttactaccgt acttgagaaa tatcctcatt tcaaaggagg tgatgccgat gtagctgata
    20401 aacctaactt tgtgactcaa actcagagtc aaacggaaac gacggaagac gcttttttta
    20461 aagcgttagg actaacaatt aaggaggact aatatgtcaa tcaattatat tactaaacat
    20521 gaaggaatat tcgaaaagaa actaatgcaa ggcgctttga cgtctaactt agagacacca
    20581 aaagtcaact ggttaggtgc aaagtctttt gagctaccaa ccatctcggt gactggctat
    20641 aaggcgcaca cacgctcaaa agggtataac gcaggtactg tatctaacga taaaaatact
    20701 tatacgctcg gctttgatcg tgacgtagag ttttttgtgg ataaggcaga cgtcgatgag
    20761 actaaccaag agctgtctat ggctaacatc tcaaacactt ttatcacaga gcatgcaacg
    20821 ccagaagttg acgcttatcg cttttcgaag attgccacaa atgcgatcga taatagccat
    20881 tttaagcagg aagatgacta ctctactact aatgtttatg agcgcttaaa agctgctatt
    20941 ttgcctattc gcaagtacgg agctggcaat atcattatct atgtctccag tgagattatg
    21001 gactttttgg agcgctcaaa ggactttaca cgctcaatcg cgacaacatc accgcaaggg
    21061 attgatactc gtgtgacatc tcttgacgga gtgcagctca tagaggtttg ggacgatgcc
    21121 cgctttaaga ctaaatttga ttttacgaca ggctttgtca aagatggcag cggtaaagac
    21181 attaactttt tgattgtggc caagcctgcg gttattgcaa aagctaaatt taactctatt
    21241 tatctttttg caccaggtca gcacaccgaa ggggacgggt atctatatca aaatcgcttg
    21301 tatcacgacc tttttgtgct taaatctaaa caagatgggg tttatgtatc ccataaatca
    21361 gcttaggagg ttaacgatga aaacatacga gaaggacaat caagtctata aagtacaaga
    21421 aggcagcgag ctggaaattc agctgattgc cgacggcttt aaagaaatta ttgaagcaaa
    21481 cgaaaaggaa actgatatca ctaaaatgaa gcttgataag ctaaaggctt atgctgaaaa
    21541 tgaaggcatt ataattcctg aagatattaa gaaaaaagaa gatgttttag cttttattaa
    21601 ggaacagcag cagagaggtg agtagtgatg ctcacctttg atttttacaa taagggatat
    21661 tgtggctcac agctgaatga agaaaagttc ggggagctgt caaaacgtgc tgagcgtaaa
    21721 attttggcac ttattggctt gaaaaaggag caagtgaaga atttgccact tgatatttta
    21781 gaggcggtaa aaatggctgt ctgcgcccaa attgagtatc ttaacgcaat aggcgttgaa
    21841 agtgctatcg gagtaacctc tgtaacccaa gctaaagtcg gcaattttag ttacacagac
    21901 ggaaagaaag cgactgtatc agctagtgtt ggctctgttg gtgttagccc tgacgtgcta
    21961 gactatctgc ttccgagtgg attgttatac aagggggtga atacgagatg gtaaaagaag
    22021 tcaaacctat ccctaaagag ttattagttg acacagttac ttatctagca gttggcaaca
    22081 aagacagctg gggagcagaa acggtagtat ctacagaatt gtcacaggtg ttagtacaac
    22141 ctagaagcag tatccaacgt gggcaacaaa acgagagtaa tagctacgag ttgttactct
    22201 tttttgattg tgtaaactcg ttaccagtag atcatcagtt taaggttgac gacaaaatta
    22261 gttatctagg aaaagagtat cgtatcgcaa gtgttgaggt actaaaagct tttgaccagt
    22321 cgccacatca ctatgaggtg atgctagaat gataggtttt aaggttgaag tcatctttaa
    22381 cgctagtaaa ttgattgcca agagtgaagc atctgcaaag acagctcgct ttgctttaag
    22441 tggtcaaatc aaaaaggata gtgacaagta tattcctgct cgtgagtgga atctgcgaga
    22501 tagcggaaga gtaactgaac gctcagtatc ttggcataca ccgtacgcta gacgactcta
    22561 ctacaatcct cagtataact ttagcaagga taagaatccg aatgcacaag gcaagtggtt
    22621 tgaggttgct aaagcaaatc atgcagagca ttggtatgag ctaacaaaga aagcctatgg
    22681 tgctgagttt agaggagatt aatcatgaca tttattgatt ttttgctcag aaaagttcaa
    22741 gaagtgagcg gagcggaacc ggtccttggc attatgggga atagtgataa ggttgctatt
    22801 atccctatgg ctggaaattt tgacaatcga gctcttgacg aaagtaagat taggattttt
    22861 actttccaag ttttggccaa gagtaaaaaa cagcaggaag cttttttgac aacagaaaac
    22921 ttggtcaatg gtctagacgg tctatcaaat gagccgttta ctggaggata tctcattaag
    22981 ctggagtgta cgacgaccac taactttgtt gaaaaagata gtgacaaaaa ttatttatat
    23041 acagctcttt tcagagcaga attaggagga taagaaatgg cagcagataa gccaactttt
    23101 tatttacaat ccgagcataa gctcgaaatt tcagaagatg gaaaaacttg gatgcgacta
    23161 gcaggtggta tcagtgaatt agaaccagac ggaaatgaag aagtatcaca agatgcttat
    23221 cttgacggct ctgaatctga tgttacagga ggtcagctag tactagcctt aactggacat
    23281 cgtctagtag gagataaagc tcaagactgg atctatgcac gtcaattccg atatgggggc
    23341 aaacgtcgtg gttttacgcg ttggacattg ccaggaggaa aaacacagtt tacctttgcc
    23401 tctacgtttg caaatatcaa aggtccatca ggagcggcta acggtaaagg tgaaattgaa
    23461 tttgaaatcc attcgaacga aacacttgta cctaataaag tagttgtaga agtcactaag
    23521 acaaacaaag aacttgcgtc tgaagcactt ggtttagaac gtcaagagcg ataagtagaa
    23581 aggatagtca gcaatggtga gacagtttga atttaagaaa acggttgaag aaattgagat
    23641 tgcaggggaa atctacttac tgcctcttga tgatgataac ctcttacgta tccaacgtga
    23701 ctttattagt tacggaaaag agatcgaaga actccaaaaa gttgaggtag aaaaaggaga
    23761 tccagacgat ctggcggata atcataagca acagctttta gtaatgaaaa aggtcatcga
    23821 gtcaccattt ggagaaggga gttttgagaa actttacgaa gcatcagggc actctttaat
    23881 gaatatggtt gacttattgg attatcttgt tgagttagtc gctgaaaaag ttgagcaaaa
    23941 taaggctcgt gccactaaag caaaagagaa gtattactcc tcgaagcgca agaaaaagta
    24001 ggtagcttat gaagttgaca gaaacatatg aagttcttgc tgatgctttt gaatttggcg
    24061 gtcatatcgt aactgttgac ttggcttttg atgtcgtgtt gcgagtcatg gagcttcttg
    24121 ccgacgcaga agtcaatgac tacgctaaaa ttgtctggac tttggatatg ctcttgccat
    24181 attttgatcg tacggagtta agttttgatg aagaatttga aattttcgaa tatatcctaa
    24241 agacgtttat ctatgaacaa gaagacggag aagatgacag tttaggagga atgtcacaaa
    24301 cgaaaacaat gcattttgaa aaggatgcag agttaatctt tgcgtccttt tttcaaagtt
    24361 atcatcttga cctatttgaa caacagggaa aattgcactg gcgaaaattt atgtcactgc
    24421 tcatgaatct gcataaagac actcctttta aggaagttgt cagctatcgt gtcatgaaag
    24481 tgcctaataa agatgaagca tcggaagagt atatcaaaca cgtcaagaag atgaagcgta
    24541 tctattcgct agaagacgaa tctgagcatc aagcgctaaa tgatgacaag ctttcagcgt
    24601 tagcagcaag gtttggaggt gagtagatgg cagatggtag tgttattatt gataccctgc
    24661 taaagactga gaaatttaac caaggtgtag ggaaactaca aggtaaatta gctggattag
    24721 gatcaaagtt gaccagcatt ggtaccggtc taactctagg cttaactgct cctattgtag
    24781 gaatcggagc ggcatcgctc agcacgttta ctacatttga aagtcaaatg aatcgtgtta
    24841 aggcgatttc tggagcaaca gcaagtgagt tcagaaaact agaagaccag gctatcaaac
    24901 ttggagcttc ctctgttttt agtgcgacag aagtagcaca agctcaagaa atgatggctt
    24961 ctgcaggttt taaagtcgtc gatatcttaa aagcaatgcc gggtgttatg tctctagctg
    25021 ctgtatctgg tggggatatg gcattagcaa gcgaggcagc cgcaacagct gtcaatatgt
    25081 ttggacttga agctaaagac gcagcccatg ttgcagatgt ttttgcacaa gctgctgcgg
    25141 atactaacgc agaagttgga gatatggcag aagccctaaa atacgccgga cctgttgctg
    25201 gggctttagg gattagcttg gaagaaaccg cggcagcaat tggtatcatg tctaatgcag
    25261 gcattaaagg gtcacaagca ggaacaactt tgaggacaag cctttcacga cttacggatc
    25321 caactaaaaa gatgcgagga atcatgtccg aattaggact tgaatttttc gatgttaatg
    25381 gaaaaatgaa gtccttatct ggtattacca aagaacttca aaccaaaatg ggtgatttaa
    25441 ctgatagtca aaagagtgca gctatctcta ctttgtttgg taaagaagca atgtctggaa
    25501 tgcttgccct agttaattct gctcctggcg cattagacaa gcaaacacaa gcacttatca
    25561 attcaaatgg tgctgctaaa gaaatggcag acaccatgaa tagtggtgtc aagggatcga
    25621 ttgaggagct taaaggttcg cttgagactg ctggaatctc cataggtaaa atattggcgc
    25681 cagccctaac gtcggttatc ggggcgataa caagccttgt gaattggttc aataacctaa
    25741 gtccgacaat gcaaaacgtg gtagttgtac tcggaagttt acttgctgcc attggaccgg
    25801 ttgtccttat tataggggtt gttactactc agatagcagc tttccagcaa ggcgtcggac
    25861 tagtctttaa tgctgtcaaa ggattacaag ctgcttttgc ctttttgacg agtcctatag
    25921 ggttagtcat cgtagccata ggtgcactaa ttgccgtatt tgtttatttg tggaatacaa
    25981 acgaacaatt tagaacgaag atcattgaga tttggacggc tatttcgaac tttttacagc
    26041 ccatcataca atttattggt aatttcataa gggaaacgtg gactcaatta gctacttttt
    26101 ggaacgaaaa tcaagcaact attatgacaa tagcccagac aacttggtca tttatccaga
    26161 cgatatttac aacagcaatt gaaatgataa aattggccgt tagtgttttt ttagggttat
    26221 tgcaatcaac gtggtctgta acttttaatt ctcttaaggt tatcgcacag gtcgcatggg
    26281 cttttatttc caatgttttc aagggaagtt tagggtccat acttgcggtt gcatctgcta
    26341 tatttgagca aattaaatca acgattgatc ttgcgatgaa aattattcaa aatatcatca
    26401 aaatcatact atccgcgata gaaggtgatt gggacggtgt attagaaggt atcaaaggaa
    26461 ttgtttccgc atttggagat tttattcaat caactttctc aaatatgatg gatactgcta
    26521 aacgcttagt cggagctgga atagataccg taaaaggaat tttcgattct ttgtggaata
    26581 ttgacttgtt cggagccggt caagcgatta ttaatggatt cttaaatggt ttgcggtcta
    26641 tgtggggagc tgtcacagat ttcgttggcg gtattgcaag ctggattgca gcaaacaaag
    26701 gtcccatctc atatgatagg gtactattga agccgcatgg aaaagctatt atggacggac
    26761 tcggtaatag catgaaaact aactttaagg acattcagaa agatgtttct ggcatggctg
    26821 acgatttaac aagaagtttt caaatcaaaa ggttcaacgg ttttttgcca gaaaagtata
    26881 ctactaagct tgatgagctt aaaaaatatg cgcaagccac gcttggcgga atgattttag
    26941 cccctaacat ggcagttcaa ccgacagtcg ttgttaacat cagcaatgaa gcagatagcg
    27001 atatcatcag gcaaaaagtc aatgctaaga atgcacaaga tgctattatt aatcagttat
    27061 tcaagaaagg gtaaaacatg ttcagtatag agtttttaga cggagagcga ctaagcgccg
    27121 atgaacgagg atggaaagtt aaagagatgt cctcatcagg acttgaacaa aacgtcgtta
    27181 gcgagtctcc taaaatgcgt tctggtcgcc ttgtttatgg tctttatcat ggcatcaaaa
    27241 cttatcaact tgtttttaca aaaatcatta aagataccct tgattatagc cgtttagtag
    27301 atgaagttaa ttactatttt ttacgtgatg aaccatacta tctttaccgc gactttagaa
    27361 agaaagctga tcgggtggac ttgccgaaga agcgggcgaa ggtgtttact aagtcaatcg
    27421 accatcaaaa aaatgggctt aaagttgaat ttacagctaa gctggaatct tatgaactac
    27481 cctacgaaga agatactgag gttcagcggg tcacttggac ggcaacacat tcatggcaca
    27541 ataagggagg gcatcgcctt gaccctcgtt attgcccaat gaagatgacc ataacagtat
    27601 caggttcagg agctgaactt aaggtgctat ttaacggtca gccttatttt tggtataaaa
    27661 aatcagttaa acaaggggat atctttatca ttgatgggac ggacgttgaa aaaaatagat
    27721 acaattgttt tgaagattgc cataagcaaa cctctttttt aaaaacagga aataacagaa
    27781 tagatattca aggagcttcg tgtgaagctc tttttgaata tagactactg tatttgtagg
    27841 agggttagta tgcaggtaaa aacaaagcaa ggtgtttttt atgttaacgc agactacacc
    27901 gtcgtcgaaa aacaaggtga ctatcctaag ctaacttgta ctattcctat taagggaaat
    27961 gagacttgga tagcagattg ccaagaactt gaccgcttat acccagctgg ggaacaagat
    28021 gaatttatta ttatcaatcc tattaaagtc actaagggga gttcgtatga tttggaaatt
    28081 acagcgatag gagcctttca ttttgaattt gtaaaggctc gtctatatga agaactacca
    28141 gaacgaatgt atactttaga ttacttgctc gatctcctgt ttaaagacag ccgattcagt
    28201 tataagctac aaggtgatta ttctactaga aggttcagtg gcttcggaga tgataacaaa
    28261 ctgactttat tccatcattt aatggaacga tttcaaacag aatttaaagt tgttggcaag
    28321 gtcgttttag ttaacacaaa agtaggtaaa gatacaggat ttcagttccg ctatcttaga
    28381 aatatcaagg atacaaagta ctcggtagac gtaactaacc tgatgacata cgttaaagga
    28441 tatggagcct ggtttgatga aaatgaccat tcaaagggaa gattaattgt tgattatgag
    28501 agccccttat ccaaagagta tggcaaactt gatggtaagc ccgttgttga tgaacgaatg
    28561 agtttaaaag aaagtcttat caaaaaatgt aagctagccg tagatcgctc tgtatctgtc
    28621 agcttaacaa cgactttagt ctctttaaaa caacaggatt atcaaggtgc ggcgagaata
    28681 ggagactcta tttggtttat tgacgaacgt atatctattg aaaaaaagat tcggttcagc
    28741 gtagtaacaa cttactacaa tgcatatgat gatattttaa agcaggacgt tactttaggt
    28801 gataaagata cctactctcg atatcaaagt ttagaaaact cttctcaaac agagacaaat
    28861 gattttcaaa aagcgatgag tagcaaactt gcagaagttc aagatgatgt taaaaagacg
    28921 catattttag tatctggcac tactaggatt ttcttttcta cagagtttcc tcaggataat
    28981 cctaagggaa ctataaaaga agatgacatt ttgtaccgta atcacgatgg gacaacattg
    29041 atgtacaggt ggaatggtgt tcaatgggaa ttagtcccgt tggtaaacga tccagatcgt
    29101 tggcgtgagg aactggagaa acaaatctct gaggctgtcg aaaagctcaa acaagagcaa
    29161 aaagtaatca accagagaac cgataaagag ctcgaagagt ttagagatac gctcaaaaac
    29221 ctatctttac cagaggaagc cattaaaaaa atcacagagg ctatcaaagt tgatgatatc
    29281 ccgtcgatta aacagtcatt tgatgactta aaaaataaag tcagcgagac aagcgagacc
    29341 gcacgattaa acgctgagat tatcgggaca gatggcaaga cccgctacaa caaaaatttg
    29401 ctagtcggcg accccaatcg cacaaaaact tatgatcaag attatataga gctcgaggcc
    29461 aacgacggtg gttttagacg cggcgagaca tacacgatta gctttagcca gacctgtgag
    29521 ttgctcaaaa aagtggctat cacgctgacg caagctaata ataagggagt taaactggta
    29581 ctgacaccta ccaaagctaa
//
LOCUS       DARYUW010000023        29584 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYUW010000023 DARYUW010000000
VERSION     DARYUW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29584
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            24..350
                     /locus_tag="TVW11_000932"
     CDS             24..350
                     /locus_tag="TVW11_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1365039.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            337..762
                     /locus_tag="TVW11_000933"
     CDS             337..762
                     /locus_tag="TVW11_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365040.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            781..1836
                     /locus_tag="TVW11_000934"
     CDS             781..1836
                     /locus_tag="TVW11_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1365041.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(1940..4222)
                     /locus_tag="TVW11_000935"
     CDS             complement(1940..4222)
                     /locus_tag="TVW11_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1365042.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4354..4887
                     /locus_tag="TVW11_000936"
     CDS             4354..4887
                     /locus_tag="TVW11_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1365043.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5094..5705)
                     /gene="rpsD"
                     /locus_tag="TVW11_000937"
     CDS             complement(5094..5705)
                     /gene="rpsD"
                     /locus_tag="TVW11_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1365044.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6229..6501)
                     /locus_tag="TVW11_000938"
     CDS             complement(6229..6501)
                     /locus_tag="TVW11_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1365045.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6518..7894)
                     /gene="dnaB"
                     /locus_tag="TVW11_000939"
     CDS             complement(6518..7894)
                     /gene="dnaB"
                     /locus_tag="TVW11_000939"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1365046.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(7915..8367)
                     /gene="rplI"
                     /locus_tag="TVW11_000940"
     CDS             complement(7915..8367)
                     /gene="rplI"
                     /locus_tag="TVW11_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1365047.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8364..10340)
                     /locus_tag="TVW11_000941"
     CDS             complement(8364..10340)
                     /locus_tag="TVW11_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1365048.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10428..12326)
                     /gene="mnmG"
                     /locus_tag="TVW11_000942"
     CDS             complement(10428..12326)
                     /gene="mnmG"
                     /locus_tag="TVW11_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1365049.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12329..12793)
                     /locus_tag="TVW11_000943"
     CDS             complement(12329..12793)
                     /locus_tag="TVW11_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1365050.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(12998..14122)
                     /gene="mnmA"
                     /locus_tag="TVW11_000944"
     CDS             complement(12998..14122)
                     /gene="mnmA"
                     /locus_tag="TVW11_000944"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1365051.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14403..15074
                     /gene="sdaAB"
                     /locus_tag="TVW11_000945"
     CDS             14403..15074
                     /gene="sdaAB"
                     /locus_tag="TVW11_000945"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1365052.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15086..15958
                     /gene="sdaAA"
                     /locus_tag="TVW11_000946"
     CDS             15086..15958
                     /gene="sdaAA"
                     /locus_tag="TVW11_000946"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1365053.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            15992..16627
                     /locus_tag="TVW11_000947"
     CDS             15992..16627
                     /locus_tag="TVW11_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1365054.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(16688..17299)
                     /locus_tag="TVW11_000948"
     CDS             complement(16688..17299)
                     /locus_tag="TVW11_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1365055.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17555..18364)
                     /locus_tag="TVW11_000949"
     CDS             complement(17555..18364)
                     /locus_tag="TVW11_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1365056.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFILLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18357..19199)
                     /locus_tag="TVW11_000950"
     CDS             complement(18357..19199)
                     /locus_tag="TVW11_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1365057.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19175..20014)
                     /locus_tag="TVW11_000951"
     CDS             complement(19175..20014)
                     /locus_tag="TVW11_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1365058.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20017..20559)
                     /gene="pgsA"
                     /locus_tag="TVW11_000952"
     CDS             complement(20017..20559)
                     /gene="pgsA"
                     /locus_tag="TVW11_000952"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1365059.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20572..21576)
                     /locus_tag="TVW11_000953"
     CDS             complement(20572..21576)
                     /locus_tag="TVW11_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1365060.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21626..22909)
                     /locus_tag="TVW11_000954"
     CDS             complement(21626..22909)
                     /locus_tag="TVW11_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1365061.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(22911..24155)
                     /locus_tag="TVW11_000955"
     CDS             complement(22911..24155)
                     /locus_tag="TVW11_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1365062.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24370..24783
                     /gene="yaaA"
                     /locus_tag="TVW11_000956"
     CDS             24370..24783
                     /gene="yaaA"
                     /locus_tag="TVW11_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1365063.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            24785..25894
                     /gene="recF"
                     /locus_tag="TVW11_000957"
     CDS             24785..25894
                     /gene="recF"
                     /locus_tag="TVW11_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1365064.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(25959..26822)
                     /locus_tag="TVW11_000958"
     CDS             complement(25959..26822)
                     /locus_tag="TVW11_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1365065.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(26993..29422)
                     /locus_tag="TVW11_000959"
     CDS             complement(26993..29422)
                     /locus_tag="TVW11_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1365066.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            complement(29425..>29584)
                     /locus_tag="TVW11_000960"
     CDS             complement(29425..>29584)
                     /locus_tag="TVW11_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1365067.1"
                     /translation="INPMGGFSIHLIINDDPDTYLRVRLSRYDLERNLEIASNYRSEK
                     LEKLLKGE"
BASE COUNT         9081 a         6466 c         5442 g         8595 t
ORIGIN      
        1 cgaggcagga agggagtaac cagatgtatt ttccagtatc tgctaccttg attgaatttt
       61 tgattttatc tattgtcgac aagcatgatt cctatggtta tgatatcagc caaaccatta
      121 agcttgtcgc taatatcagg gaatcaaccc tataccctat tttaaaaaag ctagagaaat
      181 cagactattt aactacctat agtcaggaac atcaaggtcg caagcgtaac tattacacca
      241 ttacagccaa aggcgaaaag cagctgattt tcttaaagga agaatggcaa agctacaagg
      301 ccaccctaga tggcattatt gaagggagat taaggcatga caagagatga atacctagca
      361 gagctagaca aatacctacg aaaattacct aaagcagatt attatgaagc tgctgagaac
      421 tcaagtcagc tagaacttaa cgacggcagt atcaaagact cttctatcac tgtagctgat
      481 acaaaagaag aaaacgacta tgactataca gacccctccg agcttgctat aaatcatgtc
      541 acaatcaagg agaaaaacac aattaatggc ggcgatatta atatcaatac cacattagca
      601 aatccaagag atattgctta tcatgtcaca acaagaggca acatcaagct cagctctcgt
      661 ttttcaaacg ccaagcttaa cacagacgca gcaacaggag ctacttcatt tcactctgac
      721 atagccaata ctgtcaatca aagcgaccta tcaattcatt aatcaaggga ggatatcata
      781 atgactaaac aagattttct agacaagcta aagcagcaga tcaaccattt acctcaaaag
      841 gattaccaag aaatcattga ccattttaca gagtattttg acgaggctgg tcctgaccat
      901 gaacaagcta ttcttaaaga actgggaaat ccagaggaca ttgccaagga gctattaaaa
      961 gccttagatc tccccgaaaa aacagacgaa gatgactgga cgaattggga agttgacaac
     1021 aaaacaaagt cagaagcaag ctcacaaaag cttgagccaa tagttgacat tcgctatagt
     1081 ctgcttaacc atgatttaac cattgaaact gctgacattc cttaccctac tatttcatac
     1141 gatgataatc gcatcacaat aagccaagat agtgacggca tgctcaatat cattgaagac
     1201 tcagcagtac aaacaataca gtatggcttt catttcctag accgctggct tgcaaaatat
     1261 caacccatta ccttgacact acctgtcaac caccacctga aaaaaatctc tggagaaagt
     1321 gacaacaacg atgtcaccat aaggcatata cattgtgata gcattgtctc taacacttac
     1381 aatggaacga tttctatcag tcatttatca gatagcactg tcaacctaag cagcaaaaat
     1441 gggaacatta ttttagagca ttgcaatatc cagtctagta aatgtcaagc caaaaatgct
     1501 aacctcagct gtgacaatag caccctaata aattgccagc tgaacaataa caatggaaac
     1561 atcagattag aagcaagtca gctaacagaa accttcattg aaaacaaaaa cggtaatatc
     1621 atagggcagc agctgtcctt ttccaatgac atcactatca tcaataagaa tggaatcatt
     1681 gacatcaatt gtcctagaga aaacctcatc tactatgacg taaaggcttc aaataataat
     1741 ggatttgtaa cgattagtca agaagcaggt cgtcaaacac cctttaaagc acagcttacc
     1801 atttccaata ataatggtct tatctccgta agctaaacca accataaaaa aagcttctag
     1861 aaagagctta aaccacaatt tctagaagct tttttattat atctactgtt taacgataac
     1921 ctgttatctc agctattatc taggacgatt gcttgtcctt tggacgataa atcagcactc
     1981 ctatagccat aaagcttaac aaaaagccaa ctaatacact cgtctctaaa cctatctggg
     2041 cagttaatga tattgtctga cgaaggccag agacaatata agacattgga agataaggat
     2101 ggagaatctg gaagatctga ccactcaact caataggata agaaccaccc gcagcaccaa
     2161 cctgtagcaa cagcataatt aacgaagcaa aggcaccata tcgagcatcc cagctgacca
     2221 atgcagtcac taaagccatc aaggcccatc cactcagcat aataaagcct aaggtcttga
     2281 taccgtcatt agcttcaaag cccagcagtt gaagtgcagc gtaaagaata acagagccaa
     2341 cggtcgaaat catgccattg atcagtaatt tttgctttgc ccaatcccat ctatctttaa
     2401 tcggcttacc agataaggcc tctgcaaaaa taatatttgt agacaaggca actaccatta
     2461 gagacacagc aatcatataa ggagccatgc caataccatt ggtcctaacc ttatccttgt
     2521 ccttctctga taacgctact ggatcagata ccatatcagc attctggtcc tctacccaag
     2581 ccattgaaag ctggtcagaa gcttttgata gtgaggtcgt taagcttgac agacctgttg
     2641 acagagttgt caagccatct gtcaactgag agctgccaga ggagagctga ttggctccaa
     2701 aagctagctg attagcgcct actgtaagct gctgtccacc tgctaataat tgactggatt
     2761 gatggttaag agctgttgcc cctgtagcaa gagtagacag gcctgctgta agagcttcat
     2821 tcttagctgt caattgatta aagccgccag caagagcttg actacctgat aagagctggg
     2881 ctgttgtcgc tgagtgaaca gcccttaaac cagttgaaag ctctgacaat gccttgcctg
     2941 tgctaggtag gatttgatca gcttgataag ccagctgatt aacaagtgct ttaaagtccc
     3001 tcagttgatc agctacacca gcacttgttg acatagcctc tagctcctca gacatggctt
     3061 gcagtgatgt caacatagcc tttgctgata ttgttacttt agttgaagta ttggaaatag
     3121 ctgagctcag ctcctcctgc tgctcagagt tgagaccttg ataggtagct gtagcttgta
     3181 gagcggctag ctgattgttc ttgtcagcag tatcatctac cacaagctcc tgcactaaac
     3241 gcgtcatatc ggctaaatgc ttagcaatgg ctcctgagtc cacatttggt gccaaagaca
     3301 aggaaagatt ggtctttagc tgctggatag cctgattaag ctttggtagg ctagccatta
     3361 aagcttgaat attagcttgt ttgtcttgag acagatcact tcctagagcc aattgggtca
     3421 agccagcatt taactgatta gcacccttgg ataaccgaga aacaccatct agatacgctg
     3481 gcatatcagc tgctagctgt cctaagcccg cggtatcaag ctgaccaaca ccggctgtat
     3541 aggcagctat accactagat agattacccg ctccttgaga caagcgagca cttgattcag
     3601 acaaggtgtt caaatgcctt gacattagct gactgcttgc cctagcaatt actaagccag
     3661 cggctaattg ctgaccgcca tttgaagctt cctttagacc agattggagc tgatgcatgc
     3721 tcttaaaaac ggaggtgata taggtcttcc ttatattttt agaaacagcc tctctcaagt
     3781 gattcatagc agattcaccc attttagaag cgataaagct atggccctta ctagtttgat
     3841 agctaacaat cagcttctct ggctgctgat ctaatagcgt agtggccttt tgtgacaaat
     3901 cctttggcaa cgtaatcgtc atataataac gacccttttc caagcccttt tgtgcggtat
     3961 ctgcagccac aaaatgataa tccaattcct tatttttaga catattgtct accatatcgt
     4021 taccaatagt cagtctcttg ttattcaagt aagcaggctt atcctgattc acaactgcta
     4081 caggcaactg atcaacccga ccataaggat cccacatgga ccctaaaaag gacaaattat
     4141 agagagctgg tactagagca accccaatca ttgtcactac tagcttacga tttttgatta
     4201 ttgcttttaa tccttctagc attatttttt ctccaaatag acatactgtt caaaaattat
     4261 gataaaatat attatacaaa taaagtgaca ttttacaagg aaaaaataaa ttttttagac
     4321 ataatgtcta caagtgttca aaaggagata atgatggata gccgcaagca gcaaaccaag
     4381 aaggccattc ttaatgcaat ggtgagctta ctaaaaaccg aaagcttcga tgatgtaaca
     4441 accgttcagc ttgctaaaat ggcaggcatt agtcgttcta gcttttatac tcactataaa
     4501 gacaaatatg agatgattga ttactatcaa caaacctttt ttcacaaatt agaatacatt
     4561 tttgaaaaag aataccaaaa caaggagcat gcttttttag aagtatttga atttctcaag
     4621 cgagagcaac tactatctgc tctgctatcc tccaatggta cccgagaaat ccaaagcttt
     4681 atcattaaca aggttcgtct gttgatcact accgatcttc aggacaagtt cagtaaggac
     4741 atcttgtccc caaccgaaaa ggaatatcga agcatctacc tagcacatgc ctttttcggt
     4801 gtctgccaaa gctggattgc taaaggaaaa aaagaatccc ctcaggaaat gactcgtttc
     4861 gtcttaaaaa tgctatctaa aacatagtcc tgcactaatg atgtcaaatc cagtaccaaa
     4921 aaacaacttt gtaaactatt tcttactgag tttataatga tctttatgcc taacaatacc
     4981 gacctccaat cgttagactt ttggtctaac ctttggggtc ggtacataaa tcagctaacc
     5041 gctcaaccaa aaaagcccac tgttgtgggc ttcttataat ataaagtctt atcttaaagc
     5101 attttgttgt agaattcaac gacaagtgct tcattgattt ctgggttaat ttcgtcgcgc
     5161 tctgggaggc gagttaatga tccttcaagc ttttcagcgt caaatgaaac aaaagctgga
     5221 cgtccaagag ttgcttcaac tgcctcaagg attgcaggaa ccttcattga tttttcacga
     5281 acagagatga cttggccaat ctcaacgcgg aatgatggga tatcaacacg cttaccatca
     5341 acaagaatat gaccatggtt aacaaactga cgtgcttgac gacgagtagt tgcaagacct
     5401 aagcggtaaa ccacattgtc aagacgacgc tctaaaagaa gcatgaagtt gaaaccaaga
     5461 gttccttctt tgatttttgt agcttgtacg aataggttac ggaattgttt ttcccccata
     5521 ccatatgaaa agcgaagctt ttgcttctca gcaagttgca agccatattc tgaaagcttg
     5581 ctacggttgt tagggccatg ctgaccaggt acgtagttac gacgtgccaa ttccttacct
     5641 gtgcctgtca atgacaagcc aagacgacgt gattgtttcc atgatggacc agtataacgt
     5701 gacatgtatc atgtcctcct ctaaaaaata taacgaggaa ataactgttt gaaaaatcct
     5761 gattcgtgca ggaggttttc gcctaaacag caaaggttac tcaatttagt taaccgcctg
     5821 ttgacgagct tcatattttt ctgctgttat ttcacacaaa actaattgta acatgaaaaa
     5881 ggtattgatt caagtttttt ttacattttt aatatcatat catcaaaaat ggttagctgt
     5941 aagctcaaag atgatgttaa tcatatggca aacaagcttt tacacaacac ttcccgagta
     6001 aacaaggctt tttaataccg ataggaaatt ctttgaaaat agcatattat gttttgatat
     6061 ctaataccga gagtctcaga gtaactgctt ttcaagaaag ctagtcccta ttattagtcc
     6121 gggcttcatt catttgctaa taagttcttc aaggcttcaa attgattcat atctttacac
     6181 agctgtcaac aaagtgtaaa gaaaaagccc taaatgggca ttgatttttc aatcaaaata
     6241 acgaatcagt gttttttccg tcaaaatatc tgaataggta taagactcaa cataagaatt
     6301 attcgcttcc cctgaagcat ctgggttccc ctgatactca atgataaata aagaagggta
     6361 aacctctatc aatctgccaa ccttattttt ttcacgctta cgaccatttt caagtgttaa
     6421 ctcaaccaac tgaccttcat gagccttaat gtcttccttt atttttttca ttttggcaac
     6481 atctgtaaat gcatcactca ttctctttcc ctctttctta tctttcctca aattgagcta
     6541 ttgtcgaaaa tttattgtat tccttttgaa acatcagctt aactgtccca cgcgcacctg
     6601 ccctattttt ctcaagaatc acctcaattg tattatcctc aagagcctct tctgtgctgt
     6661 cgctttcttt acgataataa tcatctcggt acaaaaatgc aacaatatcc gcatcctgct
     6721 cgatagagcc agactcacga atatcagaca aaactggacg cttgtcctgc ctctgctcaa
     6781 caccacgaga aagctgactc aaagcaataa caggcacttt taattcctta gctaaaatct
     6841 ttagctgcct tgaaatatca gaaacctctt gctgacgatt ttcaggtctt gtaccagtga
     6901 tcagttggag gtaatcaatg acaattagcc ctaagcctcc ctcaacctcc tgagacaatt
     6961 tacgtgccct tgctctgatc tcagtaatct taatgccagg tgtatcatca atatagatag
     7021 gtgcttctgc caaggctcct tgggcaatgg tcacattatt ccagtcctga tcagtcaact
     7081 gaccagtcct caagctatgt gaattgacca ttccctcagc ggccagcata cgatcaacaa
     7141 ggctttcagc tcccatttct aaggagaaaa tggcaactgc tctcttttgc tttgtaccaa
     7201 cattttgagc aatgtttaag acaaaggctg tcttaccgac tgcaggacga gctgctaaaa
     7261 taatcagttg atctgggtgt aaacctgttg taatcttgtc aagatcccta aagcccgttg
     7321 gtaaacctgt aacgtctgat gtctgcttag aacgaacctc aagattttca taattaatct
     7381 ttaaaacgtc tgagatctta cgaaagccac tgcgattgct atgctcactg atatcaacca
     7441 aggccttctc agcacttgca ataatatcct ccgagtcaga tgctccttca taggctaagt
     7501 ttacagtctc tgtcaaccta ttgatgatat cgcgtagcat agccttttca gctactattt
     7561 tagcatagta ttctgcattg gcactggtag gtacactatt aaccagctca acaatataag
     7621 acaagccacc aatatgttga aggtcccctt gatcatcaag aatcgtcctt accgttgttg
     7681 catcaatagc atcatttcga tcactaagcc ttatcattgc cctgaaaatg accttatgag
     7741 aatacttata aaaatcctct ggaccgataa attctctaac ggtaatcaac ttgtctgggg
     7801 aaataaagat agagcctagt acagactgct ctgccaataa atcttggggt tgaactcgta
     7861 actcagcaac ttcaggcaaa ctcagcacct ccaaatcttt tttaggctga tgtgctatgc
     7921 ctcagcaatg tttagtttta tttcagctgt cacttcttta tgcagcttaa ctggcacttc
     7981 gataagacca atagcacgaa tagggtgatc taaaacaata tgacgcttgt caaccttgac
     8041 cttaaattgc ttttgcaatt cctcggaaat tttcttagct gtaattgagc caaaggtacg
     8101 cccatctggt ccaacctttt ccttaaactg gacacgagtt ttttcgtcat ctaagatttt
     8161 cttaacagcc ttagcctctg ctaggatttc agcctgggct ttttcctcag ctttttgctg
     8221 ccctcttagc tggccaattg cttgactgct agcttccttt gctaaatttt tcttaatcag
     8281 aaaattctga gcataaccag tgggaacctc cttgatttct cctttttttc cttttccttt
     8341 aacgtcaact aaaaaaatga ctttcatgac tctacctctc ttgtttcttt cattgtgtta
     8401 tcaattgttt ctagtaacag ctgcttagcc tcgctaagac tgatatgctt catctgacac
     8461 gctgctaagt tgaaatgtcc tccgccgcca agcttttcca tcattctttg gacattgatc
     8521 ttactacgac ttcttgctga tatagcaatc ttatcagctc ctgtctctac aataacaaag
     8581 ctagcctcaa tatgggccat tgatagtatg gtatctgctg ccttactagc aatgacatta
     8641 ctataatatt gcccagcaag cccagttgca acgataatgg agtcgctaag gcgctcacct
     8701 ctgagaatga tctcattaac ctgcttatag tcatcaaaat cagttgctga aatattttga
     8761 atttcgacgc tatcactacc tctgcttcgt aaataactgg caacatcaaa ggttctactg
     8821 gtgacacgtg ttgaaaaatt cttagtatcc agcataatac cagccatcaa aacacttgct
     8881 tgaatcttgt ttaagcgctt cttcgcattt tgaaactgga ttaattctgt cactagctct
     8941 gcggcactgc ttgcaccact ttcaataaag gtcaagatag cattatctgg aaaatcatca
     9001 tctcttcggt gatgatcaac gacaataaca tcttgaaatt gctcgtaaaa ttccttagac
     9061 aaggttaagg aaatcttaga gtggtccacc attactaaca gtgatctagg ggtcgtaagc
     9121 cccattgctt gagaaatact gataagacgt gtcttaccat cagcctgtaa gcgctcaata
     9181 gctctttcaa tgtctggact catctcatcc ggattataga cagcaaagct gttttcaata
     9241 atgttactag caaaaaattg catgccaaca gccgagccta aggcgtccat gtccagttta
     9301 cggtgaccta cgataaacac attatcaacc attttgatac ggtctgaaat agctgtcatc
     9361 atggcacgcg tcctagttct agagcgttta accgtagaaa cagagccgcc accaaaatag
     9421 accggatttg tatggtctgc attttcacga ataacaatct gatctccgcc tcggacaaga
     9481 gcaatattca gattctcaag agcaacctga ccaatttgac aatgattttc ctctccaaag
     9541 gaaatgccca tacttagggt caatggtagc tgcgcttctt gggcttcctt tcggaactgc
     9601 tctaaaatag aaaacttatc gtccatcagc ccttttaaga tcttatagtc tgtaaaaaag
     9661 taaaaacgat ccatattaac acgtcgataa aatacctgct tagactccat aaactcagct
     9721 atgaaattag ccacaaatga atttatcttt gacgtatcag catcagataa gtcatctgta
     9781 atgtcgtcat aattatccac agaaataata ccaataactg gctttagcaa gctagaatct
     9841 gctgattgtc tactaccaac agagctatca aaaaagtaaa aaatacctga tgccacatca
     9901 atataagacg tgtatcgatt gccagaaacc tcaaaggttt gagaaatatc acttttacgc
     9961 ttatcagtga gaagctgttg gatcatctgt tcctgtaaaa aaccggcctc atcagtgaaa
    10021 atcagctctg cgtaaggatt gtaccattca atagcattgg tttcttgatc aaactgaata
    10081 acaccaactg gcatgttatc cagtaatgtt tttaaattat tttctgtttg ttcgttcaat
    10141 agctcaatgt ggtctaaatc agacaattcg taaacctttt tttgatacca aagcaaggcc
    10201 gcaacaaaca acaacactaa aaaaatagct agtgtaatca gcatttttga ttgcatgatt
    10261 ctaacacata aggctagtaa gccgaataaa atcaactcca tcataattaa atgaatggtt
    10321 tcaaaacgaa atcttttcat ctttaacctc ttaatcccgt attataccat aaaacagccc
    10381 tgaaatacag agctgtcagt ggttttgaga ttacaatttg atgactatta tgttttacgg
    10441 cgagcctttc cattaccttc aaggtaaacc attaaaatgc taatatctgc cggatttaca
    10501 cctgaaatgc gactagcctg accaatggtt tctggattga ttttcttaaa tttttgcctt
    10561 gcctcagtag caattgagtc aatagcgtcc caatcaatgg tcttaggaat ccgcttttcc
    10621 tccatacgct tcattttagc aacctgatca agggcctttt tgatatagcc ttcgtatttg
    10681 atctcagttt ctagtagctc aatcagctta gcatctaatc cctcagcagc aggacctata
    10741 aatgacacta cagtggcata gtcaacctct ggtcgacgca taaattcctt agctgtcatt
    10801 gcgtccgtca aggacttaaa gccaagcttt tgaacacgag cattggtttc tttgattggc
    10861 tttaatttga tactatctag cctctttaat tcattgtcaa attgattttt cttgatttca
    10921 aaggcagacc aacgctcatc gtcaaccaag ccaatctgac gaccaatttc agtcaatcgc
    10981 atgtccgcat tatcatgacg aaggataaga cgatattctg cgcgtgatgt cagcaaacgg
    11041 taaggctcca aggttccttt ggttaccaaa tcatcaatca ttacaccaat ataagcgtcg
    11101 ctgcgcttta aaatgagctc aggcttaccc tgaaccttca aagcagcatt gataccagcg
    11161 acaaggcctt gaccagcagc ttcctcatag cctgaggttc cattggtttg cccagctgta
    11221 aaaagccctg aaatcatctt tgtttcaagg gtagcacgaa gctgatgagg taatacaatg
    11281 tcatactcaa tagcatagcc tgttctcatc atctcagcat tttcaagccc cttaatagag
    11341 tgaaccaatt ccttttggac gtcctcagga agacttgtgg atagaccttg aacatagacc
    11401 tcctcagtgt caaagccttc tggttctaaa aagagctgat gacgctcttt atcagcaaat
    11461 cgtacaatct tatcctcaat tgatggacaa tagcgtgggc ccactccctt gacgactcct
    11521 gaaaacatag gtgctcgata taggttttta gtgatgatat catgactaat ctgattagtg
    11581 taggtcagcc agcaaggaat ctgattagcc aaataatctt tgtccttaga cataaaggaa
    11641 aaatgatttg gagtcacatc accaggctga atctctgtca cctcataatc aatagaagaa
    11701 gccttgacac gtggtggggt tcctgtctta aagcggccaa tttcaagacc aagctttttc
    11761 aaattatcag ctagtgtcac tgaggccaag ctgttattcg ggccagacga atatttcaat
    11821 tctccaagga taatctcacc acgaagagct gtacctgttg ttatgatcac tgcctgagct
    11881 gcatattttt gccctgttgc tgtcagcact ccaacaaccc taccattttc tactaaaata
    11941 tcatcaatca tagactggcg aagagtgagg ttttcttgct tttcaacagt atgcttcatc
    12001 tcacgtgcat acaagctttt atctgcttga gctcgtaatg ctcgaactgc cggtccctta
    12061 cctgtattga gcattttcat ttggatatag gttttgtcaa tgtttttccc catctctcca
    12121 ccaagagcat caatttcgcg aacaacaata cccttagctg accctccaat agagggattg
    12181 catggcataa aagccagcat atcaagattt atcgttgcta ataaggtttt acaccccata
    12241 cggctagccg ctaagctggc ttcaacacct gcatgtcctg ctcctacaac gatgacatcg
    12301 taggattctg taaattcatg taccatatct actcctttat ctcaatatgt tttatatgct
    12361 gaggctgcct gtcccaatgc tttatagccc tttttaaaca actaggattg agccttatct
    12421 tatctagatc atcaagagca acccactcac aaaccctagt acaatcaccc tcaactacag
    12481 aagggctaga atcagataat agactcacaa tataatgaaa ctcaatctga tgaaagttca
    12541 ctccttctag acaaaattga ttttcaacca caaaggctaa ctgagcaact gaaacctcag
    12601 ctcctacctc ctctagaacc tcacgcttga cagcttcttc tgtgctttct ccaacatgaa
    12661 tagcaccacc taaaagataa tagtcctctt tgggtgattt ggcaagataa atatagccat
    12721 ccttaattat taacgctgaa gccctaacac caaagctatg gtctgctatc cttgttctaa
    12781 aatcctgaac catcttttct ccttgacact gtttttaagc tataaaaata gtcaaaacct
    12841 gagaaagctg taagccaaaa agacttacaa ttcccatgag ctttgaccat catcgttatt
    12901 gttaacctta ttctatcaaa atctgccagc ttgtcaagac ttatcagatg acaaaaccgt
    12961 caactttatt gacacatctg tcaattaaca tgtcaagcta aatatattga caaggctcgc
    13021 catctttata cgccatatca ataataccac caccaagaca ctcatgacca tcataaaaaa
    13081 cgactgcttg accaggtgta atcgcacgct gaggctcagc aaaaacaacc ttagctttgt
    13141 ctttcttgac atgaaccgtc accttagaat ctggctgacg atagcggaac tttgctgtgc
    13201 attctaaggt gaattcttca ggaacttctc ttgtaaactg aatgacagaa gcgtcaagac
    13261 tagttgacat taaggactcg tggtaaaagc cttgaccaac ataaaggata ttttgtgaaa
    13321 ggtcttttcc aacaacaaac caaggcttgt tatctccacc ctgctgacca ccaatgccaa
    13381 gtcccccacg ttggccaata gtataataca tcaagcctgc atgctctccc atatcacgac
    13441 catcaacagt catcatacgc cccttttgag ctggtaaata atggctaaga aaggtcttaa
    13501 aattcttctc actaataaaa caaatccctg ttgagtcttt tttctttgct gttgcaaggc
    13561 ctgcttgttc agcaatagca cgtacctctg atttttgcag gtgccccaag ggaaacatgg
    13621 ttttttggag ttgctcttgt gatagttggc ttaaaaaata ggtttgatcc ttacccttat
    13681 caagaccacg cagcatatgg actacaccat tctcatcacg tttgatttgg gcatagtgac
    13741 ctgttgccac ataatcagca cccaatgtca tcgcataatc aagaaaggct ttaaacttta
    13801 tctccttatt gcacatgaca tcaggatttg gggtgcgtcc tgaacggtat tctgctagga
    13861 aatactcaaa cactctatcc caatactctt tttcaaaatt aacagaatag taaggaatac
    13921 caatctgatc ggctacggct gccacatctt tataatcctc agtcgccgta caaacaccaa
    13981 attcatctgt atcgtcccaa ttcttcataa agacgccaat cacatcatat ccctgctcct
    14041 ttaacagcaa ggcagttaca gatgaatcaa caccgccact catgccaaca acaacacgtg
    14101 ttttcgagtt atctgtcatc atttattctc ccatcaatat aagatacaag gacatgagaa
    14161 aaagaataga acgaatcaac ttgcctaaac aagactctag caaatggttc atttctatat
    14221 tttttgtctt tgtccaagtg ttttctcaaa gctcgatttg aaggtcgatt tgaagcgccg
    14281 ctagacgcat gactattata acagtattgt ctcttatttc caacaatatc ttttttcata
    14341 acaaacgaca tttgattagc gatttgttat aataaaaagg ataaaaagag catggagcat
    14401 atatgaacac acaaaaattt caatcagttt ttgacatcat tggaccagtg atgattggac
    14461 catcgagcag tcataccgct ggtgctgtta gaatcggaaa ggttgtccac tccatttttg
    14521 gagaaattcc tgatgaggtg acctttcatc tatacaattc atttgctaag acctatcaag
    14581 gccatggtac cgacaaggca ctagtagctg gtattatggg catggatacg gataatccaa
    14641 acatcaagaa ttctcttgaa attgctcatc aaaagggcat taaaatttat tgggatattt
    14701 taaaggatag caatgctccc caccccaata ctgtaaagat tagtgtcaaa aaggctgata
    14761 aagcaatgag cattacaggt gtgtcaattg gaggaggaaa cattcaggtc acagagctaa
    14821 atggtttttc tgtttccttg tctatgaata ctccaacctt gattattgtc catcaagata
    14881 tccccggaat gattgctaag gttacagata tattgtcagc tagtgatatt aatatcgctc
    14941 aaatgactgt gactcgtgaa agtgcaggtg agaaagccat tatgattatt gaggttgatt
    15001 ctcgtgattg tcaagttgct gtcaagcaga ttgcaactat tcctaatctg cataatgtca
    15061 atttctttga ctagaaaggt atattatgtt ttacacaatt gaagagcttg tcaagcaggc
    15121 tgatgatagg tttgatggta atgtagcaga gctgatgatt gctacagagg ttgaaatgac
    15181 tggtcgaagc agggcagaaa tcctatccat catgtcacag catttacagg taatgaagga
    15241 ttctgttgtc agcggattga cagcaaccaa atctattagc ggattgactg gcggtgatgc
    15301 tcttaagatg gatcattaca tcaaaaaagg aaaggggctt tcagatcaaa ccattttaac
    15361 agctgtgaga aatgctatgg ctgtcaatga gctaaatgca aaaatgggac ttgtttgtgc
    15421 aaccccgact gctggaagtg caggctgtct acctgctgtc cttgctgttg ctattgataa
    15481 gctcaagcta tcagaaaagg aacagctgga ctttctcttt acagcaggtg cctttggctt
    15541 agtcattgga aataatgcct ctatctccgg agcagaagga ggctgtcaag ccgaggtggg
    15601 ctctgcctct gcaatgagtg ctgcagccct tgttaaggca gcaggtggta ccgcttatca
    15661 ggctagccaa gcggtagcct ttgtgatcaa aaatctattg ggattggttt gtgatcctgt
    15721 tgctggctta gtcgaagttc cctgtgttaa gcgtaatgca ttaggatcaa gctttgctct
    15781 tgttgctgct gatatggcat tagcgaatat tcagtcacaa attcctgtag atgaggttgt
    15841 tgatgctatg tatcaggttg gtgccgcaat gccaacagcc tttaaggaga cagctgaggg
    15901 aggattagca gcaaccccaa caggtagacg gtatagtaaa gaaattttcg gagactaata
    15961 taatcaagta acgatagact gaggagacgt catgaaagca atcctatttg acttagatgg
    16021 tactttggtg gattctagta taggaatact aaatgccttt gaatacacct ttcaaaaaat
    16081 gaaaatccct tgtcctgatc atagcatatt atcgtcttac atcggaccac ccttagaagc
    16141 gaccttttca gcatttttta ggaatcagca tgatgtcgag gttgctataa cacactttag
    16201 agatttttac agggaattag gcatttacca agcaaggctt tattctggaa tcacagagct
    16261 attagataat ctctcgcaag aaggtcttga cctctatgtg acaactagta aatatgaacc
    16321 tatggcaagg caaatgcttc aggatttaac gattagccat tatttcaaag ctatcctagg
    16381 ctctatttct aatcggtgtc acaagttgga tatcgtcaag gcatgcttac aagattttgc
    16441 tattaataaa aaagaagcta taattgttgg agataccaaa tttgacatga ttggtggtaa
    16501 acaagcaggc attacaagac ttggagttac ttggggattt ggttgtcaag aggatttaca
    16561 agcacatggc gcacaataca ttggacacac accccaagag gtgattgaga ttatccagtc
    16621 attgtaaaac gatactaaaa acctatcatc acacaagatg ataggttttt aacgctgtta
    16681 tctgttctta gtagccccaa gctgataagc cctgtgcacg ataggcattt aaggctgaat
    16741 ttacctgatc ctgaacggtt gcagttgatc cccagcctgg catggtttgg aataatcctg
    16801 aagcacctga aggattagct gcgttagggt ttccatttga ctcacgagcg ataatggctt
    16861 cccaagtagc ttgtggaaca ccagtagctg ccgccatttg agctgctgct tcactaccga
    16921 tagcccctgc ggtattgccg ttagaaagga ttactccatt gctataagcc actggtgtag
    16981 ctgcatactg agcttgagga gcagcctctt gcacagcagg actagctacc tcagaagcta
    17041 ctgattcctg agctggtgct gcatcagcag aggaaggctc tgcctgctca gctggctgct
    17101 ccttggttgc agcctttgct actgttgatt tttttgtttt atgatgtttc ttcacaacct
    17161 tagtatcaga agctttagca taggaatcag tgtttacatt ttcacttgaa aaagcaaaaa
    17221 ctactgcgag caaagcaata gcagctgcta caatgccaaa actaaaataa cgttgtttca
    17281 aaatgtcttg tttaaacatt aaataaatac ctcacttttc tctgttatcc atattaactg
    17341 ttaattatta cttgtctatt taagatatat taaaaatatt acagcaatat tgatattcca
    17401 agttttctag cctgatatca gtgttttttg agcttaagaa gctcaaaata aaaacaatgc
    17461 ctaagttcag acctgtgtaa cagatgattt aagcattgtt attattaata aattctagtt
    17521 gctacagcct aacaaagggg ctgctgtaat atagctaggt gagccttgag ggacttttta
    17581 gacagaaaag gaaaatcccc aaaatgacta ccaaaataat ggctagagtg tcttttaatt
    17641 gccagcttag caggcggtat tttgttcgac tgtcaccgcc ttgatagcct ctagcctcca
    17701 tagcgatcgc taaagcgtca gctcttttaa agcttgaagc aaaaagagga atcaaaatag
    17761 ggataatcga ctttaccttt tgaataagat tgccttctcc aaaatcaaca cctcgcgctt
    17821 tttgcgcatt cataatacga gttgtatcgt ccatcaaggt tggaacaaac cgtaagctca
    17881 aagataacat caaaccgatc tcatgggcag gtaccttaaa cctaactaaa ggcttcaaca
    17941 gcgcttcaac agcatcagat aagcttagtg gggtggtggt tagggttaac agcgtggaaa
    18001 agaaaataat caaaacaaat cgcatgaaaa tcaaaatggc ttgacttaat cccaagcttg
    18061 ttatcttaat tattccaagc tgaaaaagaa ctgatcctcc ctgtgtaaaa aaaacttgaa
    18121 aaagcgttgt aaataggata ataccaatca taggcttaac accattgaaa aagaaagacc
    18181 attttatctg tgacaagaaa atcagcagca agataaatgc taacagcaaa agattagtta
    18241 ccacattatt ggcccaaaaa ataatgataa tatagataat catagcaagc agcttgcttc
    18301 ttggatcaag ccgatgaata attgaattcc caggaatata gcgaccaaga atgagtttat
    18361 ccatgcttta atacctctct taattcctcc aaagtaatgg gtaaataggg taaatcaaag
    18421 ccttgcttag ccaggcgttg ggcaaaggct gtcaccttag ggacacctaa ttgtttttct
    18481 tttagcaaat caatgtgttg aaaaatagcc tttggctgac ctgataagat gattttacca
    18541 gcttcaagga cataaacaaa atcagcataa ttagcaacat cgtccatcag atgtgtcacc
    18601 agtacaatgg tcatgcctga ttgatggagc gatttaaaaa gactcattaa ttcctttcgc
    18661 cctttgggat caagcccagc agtaggctca tctaacacca aaatatccgg ctgcatcgca
    18721 agaatacccg caatagcaac cctgcgcatc tgcccaccag aaagctcaaa tggattttta
    18781 ccaaatagtt cctctgaaat ccctactagg gttaattttt cacgcgctaa agcttccgcc
    18841 tctttctgag aaacaccaaa attttgtggt ccaaaggcaa catccttcaa aaccgtttcc
    18901 tcaaaaagct ggctctcagg aaattgaaag actagaccaa cctgcttacg aataggctta
    18961 atatctttat tttttgactg actagttatc tccttgcctg ctaccgtaac cttgccggtg
    19021 gtcggcagat gcaagccatt taagagctgc ataatcgttg acttgcctga gccagtatga
    19081 ccaataaaag ccgtataaga gccgtctaca atatcaagat taacgtcaaa aagggcacgc
    19141 ccctcaaagg gtgtccctgc ttgatacgtg tagcttacat tttggaaatg aattgacata
    19201 gctgttcctc taattccttt tctgtgagat agattccctg tatagggtag ccgtcttttt
    19261 ttagcatatt aacaacagag gttgtaaaag gaatatctaa acctagattg atcaattgat
    19321 tgcccctagc aaatagctcc tgtggagtcg agacagactc aacacgccca ttgttcatca
    19381 ccaaagctcg atcactaaga gccacctcat caagatcatg tgtaatagat ataacagtta
    19441 gttggtattc ttgtctaata gattgaattg tccgaatcaa ctccagacgc ccctttggat
    19501 ccagcatact ggttgcttca tctaaaatga tgatcattgg ccgcatggca acagcacctg
    19561 caatagcaac ccgctgcttt tgaccacctg ataatctgga aggctcctta tccttaaaag
    19621 cctccatacc gaccagctgc aacgcctgat gaacacgctc tatcatctcc tgatgggaaa
    19681 cacctttgtt ttcaagacca aaagcaacgt catcttcgac agttgcacca acaaattggt
    19741 tatcaggatt ttgaaatacc atgccaattt tatgacgaat gtcccagaca ttgtcctctg
    19801 taagaagatc accatcaaca aaaatctggc cggcttctgc tttcaatagc ccatcaatta
    19861 acctaacaac ggttgacttg cctgagccat tatgcccaat gatagacaac cactcgcctt
    19921 gtttcacatg aaacgtcaca tcatctaggg tatatcgctc ctggtcctgc ttatacttaa
    19981 atgtaagatt cttaacttca ataatatttg acattgttat ttaaaggtat ccttaaaaag
    20041 aaagcttgct cctttgaaat aatcgtaacc tgaataaatc gtaaacaata gagcaatata
    20101 cagcaaaaca gtgcctaaaa cagtccaatg acacagtaaa aagatgatgg aaagcatctg
    20161 tgctactgtt ttgatcttac caggcatagc agctgctagg accttatctc cagtctcaac
    20221 caatagcaaa cgaagtcctg taacagctag ctcacgacag ataataaccg ctgacaccca
    20281 agccggtacc agctctaagc ccactaacat aataaaagca ctcatgacaa gcatcttgtc
    20341 tgccaatgga tcagcaaatt taccaaaatt agtaacaacc tgccacttac gtgcaaggta
    20401 accatctaaa taatcggtca ggcttgccac tgcaaaaata atcgctgcaa aggtatgcca
    20461 accgactgtc tttgaaaaag aggtgatcaa caaaaacaat ggaatcatga cgatacgggc
    20521 gagagttaac aaattgggaa tattttcttt tttgatcatg cttatacctt attattgtat
    20581 cttcagtgtg atatagctga tatcagtact tgtcattgct gataaatcta ggggctgacc
    20641 atcaattgct actgaaacac cctttgttac gcctagtgtc aacaaggatt ctgttgtctc
    20701 agcaggcaag gtagtagaat aagtcggatt gtcctttgtt agggtcatac cagcctcacc
    20761 aatttccgaa ttagtgaggg aaatccaact gctctcagca tcagtcagtg acactgtaac
    20821 atcaacagct tcttttgatt tagtaatatt agcaatcaag taattctctg cgccctctgt
    20881 tgtgatcacc gtcttaggct cagatgagct ggacgctgtt gagtgactgc tttgtgatga
    20941 cttaagaaaa gacatctcag cctcttttgc tttttgacct ttatcaaatt gcttccaaac
    21001 agcaaaacca ataacaccaa caatagccac agcaataaga cctagtaagg ctgatggaaa
    21061 ggctgatttt ttcgttttag cactatttcc ataacgactt agccttgaag cactggtctc
    21121 tctagtccgt ctatggtcag tagccttaaa gtgactagct gtaggagctg atttgcttga
    21181 ggatagtgac gtcttgacag gaatcactag ggtttctggt tgagtccttg aaggctctgg
    21241 ttgagctatt ttttcagaat agctattctc ttgtagcctt tttttgctga gcttttcttc
    21301 aacgatttgt gtgactgatg gtgtacctgt ttccttttta aagctcacct gcagctgata
    21361 caagcgtttt aagctatcaa agtctaagcc aacaatatca gcatattgct ttagaaaatg
    21421 accaaacttt tcttctggaa tgattttgaa ctggtcaagc tccattgcca atagataatg
    21481 cgaggaaatg ccagttttag cttcaatttc gtctaatgtt atgttttttc cgacacgtgt
    21541 ttctcttaat aattcaccga gacttgtttc tctcatacga gtacctcaaa aatattgtaa
    21601 taagaccatt ataacagatt ttaagctatt tgggaaagac tgtaaaatct gaagtagctg
    21661 catgctcaaa aaacaagctt cctatttcga taatatcctt taaagctagg gtctcaataa
    21721 tcctaggaat atcaaaatag gtctcttgct ctgataaatg aaggctaaat tggcttgcca
    21781 gctgatcaat agcgtctaag ctttgcataa aatccccata catttccttt ttcactagct
    21841 ctaagtgctc ctcattaacg tctcttgagc atctaaaatc ggaaatcttt tttctaatgc
    21901 tgttagacat tgcaataggc tgactagtat ctgaagaaat caatacaaat tggaaatccc
    21961 tttgaatgtc aacctctata tcaaaggagt cgtctatctt gcccttttca taccaatcct
    22021 gataggtttt tgacgtccag ccaaggagca ccgctaggag cagtctaaga gctacctgat
    22081 aggtgagtag agaatactcg cttgacatta gctgaccgcg aaagccgact gctaatttgg
    22141 cagtcgcaac gtccatatca atagatctag acttgatcac agggtagtag gtcaatggag
    22201 ctatctgtac atcatactgc gtctgacttg gttgactatc ttgaaaggct tcaatagctg
    22261 taaaggcttc ttcaatgtca atatcgccaa taatcgttaa gaccatgtta gaagggtgat
    22321 aaaaataagc atggctgtca gccaataaag agcctgtaat gtccctgata gactccttgg
    22381 tcccagcaat atcaacagct aagctggtat tgggaaagag gttctgtaag ataccactgt
    22441 aagcctgata atcaggatcg tcctgataca tctcaatttc ttgagtgata atatgttttt
    22501 cacgattaac cgactcctct gtaaagctag gagctgctac aaattcctgc aaaagtctca
    22561 gactttcttg ccattcattg acagttgaaa agaaatagct cgttttatca aaggttgtaa
    22621 aggcatttgt ttctgatcct aactgtgtaa atgtaagagc aatatcatta ccatctttat
    22681 cctcaaatag cttgtgctct aagaaatgag caacacctga cggcaagtca aacctttgac
    22741 aattgactgt aaagcttgtg tcaagagaac caaaacgagc agtcagcata gctgttttct
    22801 cagaatagcc ctctttcttt atcaaataaa cccttaaacc atttgccaat tgaccgtagt
    22861 gtaaggtctc tttaatgctg ggatagtctt ttttcagtag tgacgtcatc ttattttccc
    22921 tctaaaaaat atacagcttg cagcttgagt agattagctg tcctgacaat atctagcttg
    22981 ctaaccttgt caatctcgtc aagccaactt gacaaagtat aggaaggatc tatataagat
    23041 ctcatgtatt ccagctcaat caaggcttta ctattatcct cagatagcaa ggcgttattt
    23101 tttagcatta gctttgtttt cttgacaagg ctgcttgaaa agcgccccat cttgatgtca
    23161 ttgagctctt taaccattag ctgcagggct cttgtccggt gctgtctatc tatgccagca
    23221 taagcctcaa ataagcctgt gtaaacatca aatcgactac caatactata ggccagcccc
    23281 tccttctcac gaatttgggt aaagaagcga gagtgtgtaa aggctcctaa tagaccattt
    23341 aacacaacta aggcataata ctctgcttgc ccataaacca gcggaaaatg ataggctagc
    23401 tctaaaacag actgattaag ctgcttttgc tcgaccaatt cgttgacaac attgacaggc
    23461 tgctgtaaat aaaagaaatc tagctttttc ctgcgtccct caaagggaaa ttggtgtaac
    23521 aattgtacca tacgataatc atcaaaatca ccaagaataa aaatatcaat ctgatcctca
    23581 ttcaacattt tatgaaattc ttgatagctt gtgtaggctg tttctttagc aattaactca
    23641 gtattaccat attttgacag cttcaggcta tcattagcat aaaataattg cttggctttt
    23701 agggcactat aataaaagga atcctcctta tctgcctcga cataggtcat caaatgtctt
    23761 ttttcgatgt caaatagttt gggctggtac tgagccactg ataacaaagg agaaaaaagg
    23821 atatccttta gaaattgaat catttcgtct agaagcttct ctccataaaa agcatactga
    23881 tcctgaataa aggtaatgtc aatatccaca atatgaacca aacccttggt tgacacatga
    23941 gttgacaggc ttgctccata catttgtgct aatttttctc taaattgctt ggcagtagga
    24001 taggtatcgt tagccgttgc taacatttga gctactaaga ctcgctttgc taccgttttt
    24061 tgattcaaat cacctgaaaa gcgaaacgtt atctgattcg ttttaaatgt tttgtttttt
    24121 atcagatgaa gctgaactcc ctgaataagt ttcataatat ttccttatta ataaatgtgt
    24181 gatctctaga attataccat ttttatcgct attcgttgag tgttaacatc agtctggtag
    24241 cctattttga ctctttatca aaatgctatc ctgtggctat agtctagact ttagaaggtc
    24301 agcatttcag cattattatt tagtggcttt ttatgctata atgacttgaa tgacaaattg
    24361 gagatgacta tgacatacac actatttact gactttatta ccctacaagc tttattaaag
    24421 gagcaaggta ttatccaaag tggtggtgcc attaaaggtt ttttagctca aacagaggtt
    24481 tttttaaatg gtcaagagga acaacgacgt ggcaagaagc taagagtcgg tgacgtcatc
    24541 accattccat cacagcacat caagattgag cttgtagcgc ctagtcaggc cgaaaaaaca
    24601 gcctatgaag ctgaaaaggc agaaaaagag cgagttgcta agatggttaa acaaatgaat
    24661 caacaggcta aaaaagcaca gaccaagcaa gcagctacta ccaaaagcaa gcgtggtcaa
    24721 gctacctcag ctgtaaaagc taagtctaat caccaaaagc ctattcgctt cccaggattg
    24781 tagcatgtgg atcaaagaac taaacctcac ccattaccgt aattatcaac aagcctcagc
    24841 agccttttca ccgggcttga atgttttcat tggtgacaat gcgcagggca agacaaattt
    24901 tcttgaagct atttattttt tgtcagtaac aagaagtcat cgcaccaaat ctgataagga
    24961 cttaatctac tttgacgaaa gggattgctc tatatctgga actcttgagc gccttagtgg
    25021 tcgtgttcag ctagaaatac tgctgtctga taagggacgg atcaccaaga ttaacaccct
    25081 aaagcaagca aagctttctg attatatcgg agcaatgatg gtggtcctct ttgctcctga
    25141 ggatctacag ctggtcaaag gctctcctaa tcttagacga aaatttatgg acattgactt
    25201 aggtcagata aagcctgttt acttatcaga tttgtcacat tacaatcatg tcctaaagca
    25261 gcgaaatgcc tatctcaaaa gtgttcatca gcttgataat gactttttat ctgtgttaga
    25321 tgagcagctg gttacctacg ggagtcgtgt aatggcgcat cggttggcgt ttgttcaatc
    25381 actagcaaaa gaggcaaaca agcatcatca agctatctct aatggcctag agaagctttc
    25441 gatctcctat caagcctctg tgagctttga gcaccagcaa gagatttatc agcaattcat
    25501 gaaccagctc aaaaccactc atcaaagaga tttcttgaga aaaaatactg gtgttggccc
    25561 ccaccgcgat gatctggttt tttatattaa tgacatgaac gctaattttg ctagtcaagg
    25621 ccagcatcgt agcctgattt tatcactgaa aatggcagag gttagtctga tgaagcaatt
    25681 aacaggtgac aaccctattc ttctacttga tgatgttatg agtgagttag acaataccag
    25741 acaaacaaag cttctgggag ctgtcaagaa agaaaatgtt caaaccttta tcacaacaac
    25801 tagcttagag catttgtctc agctacctaa ggacattagt ctctttaagg ttaataaagg
    25861 aacaatagaa cgagattcta tcatgattga ttaactgagc aaactaaaaa aagggcacct
    25921 taatagtgac cctttttacg gttaaattag ttgatactct atgatttgac gatacctaag
    25981 aggatagcgc caacaataaa gcaaaggata cctgtaatga cccagcgcat ctcttttttg
    26041 gtttttgtct cacctaagaa taaaatacct ccgacaatag agataatagc gcccaattgt
    26101 gaaaagctaa aagcaatcgc cagaccagcc tttgaggctg ctagcagcat gaagatattt
    26161 ccaactcccc aaagcaagcc aacaacacta tttttgataa catactggtc aaacgatacc
    26221 ttaaacgaca taaacatggc tgcaccaagc accattccca ctgccatcgg taaaataacc
    26281 gacaacacat caaatttcat aatgttattg aacagcacag catacatcac atagccggtt
    26341 gtcgagtagg ttaaggctct aaagcccttt gaaaaatcat gcaattgatt acttgctgca
    26401 ttcgtctcgt cctgcttgct tgaaaaataa aaaccaacaa tcaaaagaag taaggcaatc
    26461 gtaccaacga caaattgaat aggcttggtc cactcatgaa agaccagcac accaatcagg
    26521 ctacctaaaa ctagctgaga accactagac aagggatttg ctactgaaac acccatatac
    26581 tgcatggcat gaaattgccc agtctgacca acagaccaga taataccacc taaaatccca
    26641 aaaatccaga gcttcataga catctcaggt ctgactacta accaaacaac tagagcaaat
    26701 agtaaagctc ctatggtcat tccaaaggtc tgctgtgagg gtttaccgcc aattttatta
    26761 ctaacaaagc caatacttcc ccatgcaaac attgggacaa gtgcaaataa aataccttcc
    26821 aaatttacat ctcctttaca ataagttgac acatgatgtt aacgataaaa gtgctttcat
    26881 acggagaatt attatagcct atttccttag aaaatacaat aacatgatgt aaaaaatcat
    26941 ctgctcacac gcttctccct aaaaaggtgt caaagtagct gacagagctt atttactgca
    27001 atgctagagg attatttaat gaaaaccgtt tgaccttatg gctggctcta gctggagctt
    27061 tgttagggac ttttgtgacc tgagttccaa agcaatcagc aactagctga ctgaaatagc
    27121 ctaagcgttt gaggagtaga gcaagatgat taaccatagc actagctgct tgaccggaca
    27181 tgcttgcttc tatggtagct ttgacaaagg atagctcaac gatgatttta tccagcagtc
    27241 tgccaaccat cttttgacta gtgatgatgt catctaaatc aagagcgctg taaactcctt
    27301 tttcgatcaa tcgactgaga tctccatgca agttttgaag ccgatgcctt gcggtattga
    27361 ctcgctgtat cgtatcagtc aatgccggta ctagaggaca tacctcagct ctggcagaag
    27421 caataccgga tcttatgcgg caaggatata aagcacccag atttccccaa tagctccttg
    27481 tcgttgtaga ggtttcatct ttgatttctg ttcgttcaac ataaacccta tctgaaaaac
    27541 gtctctctaa tactgtcacg atattcttaa agatattcac ctcagtagtc caataatcaa
    27601 gtgtatcaaa tagccttgaa aaggttgacg cataaacaga ggcaaccttt ctggaatagt
    27661 cccgactctt ttgttccacc tgctcatcaa aggcttggag aatatctctg acatcatcta
    27721 aaagacctgt tctttctagg taagcatcat agctgcttgg gacacagacg acatcagcac
    27781 ttccttgaaa ttgaccattt tttaggctgt tgcctagcca gttatctgta gctgtgacat
    27841 tttgtgatac ccctaggatc agctcactgg tattgattat cattttttcc agctctatga
    27901 tatcctgtaa ttccacgcta aatacctctt ttaaggaatc gctaataccg tcaactttac
    27961 tttcacgtaa acccgttcct tcaaaggtct tatcactctc cttcaatagc tgacgactgg
    28021 cctcatcaat aatctgccaa gatttcaaaa gtgtcgagcg accgataata ctatcaatcc
    28081 agcctgactt ttcatgctga gcagatgagg caagctgaag cgattttgtg tttaagctcg
    28141 ctaattctga atcatacatg gccagattga ggcgattatt attcacatat gggatctcat
    28201 cataggaaaa gggatagtct aggctagccg aatgagacag catatcaaac aagtcctgct
    28261 gaccaactaa tctctccaaa gaactttgca ggctattaaa agtatcggtt aggccatttg
    28321 tagcaagcag ggctttgatg ttttctgaaa ctcgcttttt cctctcttca aaggagtctt
    28381 ttatggcatc attttttgcc tgacattttt cagtaatgtg gcgaatcgtt tgcaggtcgc
    28441 ctgatataga ggattgaagg ttttgtgcaa ggttagtcag gacaccagca ttgatgacaa
    28501 tcgtttgctt atcagaaagc acaccgtacc gagccgatgt tgacgaatca aagtaatttc
    28561 taaagcctaa gtacagctcc tctaccttag tgtctaatcg gttatcgctg tcaatatcaa
    28621 taggcaacag gacattagca tgaacaaacc ggccatttac gtctgtcatg ttgccatatt
    28681 gatcatactg atagccatgc cacatatgct gtaagactat atcattgacc ttttttgtat
    28741 tgacaacaaa gacctgaccg actgctccct ccttttggtc aaagcccata ccaatgatgt
    28801 catgcggatc cacatagttg taaatgcggt catgcaagag ctttgcacgt tttctttgat
    28861 actcattaag cacacgatag gtgttggggc cattgtagat atagactcca gagatacgag
    28921 ataagttttt atcactaaca gaggtaacac cgtactgaac tgtcatggag cctagcgaat
    28981 gaccataaaa ctcaaatgtt gcgttagggt attgctttaa tgtcttattg gtaaaggttg
    29041 ctgcctttcg gagctgagct gtccctttag ttggtgtctg gtccggtaaa agaatgcgca
    29101 tagccatagg caaatcattg cctacccaat ctgcaaccac atctactggg tgtttctgcc
    29161 actggtctgg gccagtagag ccccggtaca gcatggtgac atgcttgacc tgagcatagt
    29221 ctgccttggt aggatgaggg ggaagcttga catctgtcac gacataggct tgaaaacctg
    29281 atatcgaatc ctctatctga gacacataac cgatggaaaa ctcagaatta tcatcatcaa
    29341 ttaaaactgg tgaacctact gtatgttttt catactcttc ctcagcaatc cgttgtctct
    29401 gttcgtctgt caggatcatc attttcactc tccttttagt agtttttcta acttttctga
    29461 gcgataatta ctagcgatct ctaaatttct ttctaaatca tatctactaa ggcgaaccct
    29521 taaataagta tctggatcat cattgataat caggtgaata gaaaaacctc ccattggatt
    29581 aata
//
LOCUS       DARYUW010000024        29509 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYUW010000024 DARYUW010000000
VERSION     DARYUW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29509
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            89..1360
                     /locus_tag="TVW11_000961"
     CDS             89..1360
                     /locus_tag="TVW11_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1365068.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            1454..2590
                     /gene="recA"
                     /locus_tag="TVW11_000962"
     CDS             1454..2590
                     /gene="recA"
                     /locus_tag="TVW11_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1365069.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            2966..3364
                     /gene="spx"
                     /locus_tag="TVW11_000963"
     CDS             2966..3364
                     /gene="spx"
                     /locus_tag="TVW11_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1365070.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            3477..3746
                     /locus_tag="TVW11_000964"
     CDS             3477..3746
                     /locus_tag="TVW11_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1365071.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            3743..4162
                     /gene="ruvX"
                     /locus_tag="TVW11_000965"
     CDS             3743..4162
                     /gene="ruvX"
                     /locus_tag="TVW11_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1365072.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            4172..4471
                     /locus_tag="TVW11_000966"
     CDS             4172..4471
                     /locus_tag="TVW11_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1365073.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            5019..6578
                     /locus_tag="TVW11_000967"
     CDS             5019..6578
                     /locus_tag="TVW11_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1365074.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            6675..8873
                     /gene="nrdD"
                     /locus_tag="TVW11_000968"
     CDS             6675..8873
                     /gene="nrdD"
                     /locus_tag="TVW11_000968"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1365075.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            8979..9125
                     /locus_tag="TVW11_000969"
     CDS             8979..9125
                     /locus_tag="TVW11_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365076.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            9153..10088
                     /locus_tag="TVW11_000970"
     CDS             9153..10088
                     /locus_tag="TVW11_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1365077.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            10101..10595
                     /locus_tag="TVW11_000971"
     CDS             10101..10595
                     /locus_tag="TVW11_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1365078.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            10605..11219
                     /gene="nrdG"
                     /locus_tag="TVW11_000972"
     CDS             10605..11219
                     /gene="nrdG"
                     /locus_tag="TVW11_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1365079.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(11677..12408)
                     /gene="yaaA"
                     /locus_tag="TVW11_000973"
     CDS             complement(11677..12408)
                     /gene="yaaA"
                     /locus_tag="TVW11_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1365080.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            12862..13065
                     /locus_tag="TVW11_000974"
     CDS             12862..13065
                     /locus_tag="TVW11_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365081.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            13067..13520
                     /locus_tag="TVW11_000975"
                     /pseudo
     CDS             13067..13520
                     /locus_tag="TVW11_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            13530..14204
                     /locus_tag="TVW11_000976"
     CDS             13530..14204
                     /locus_tag="TVW11_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1365082.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            14234..14671
                     /locus_tag="TVW11_000977"
     CDS             14234..14671
                     /locus_tag="TVW11_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365083.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(14894..15667)
                     /locus_tag="TVW11_000978"
     CDS             complement(14894..15667)
                     /locus_tag="TVW11_000978"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1365084.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(15751..16818)
                     /gene="pepA"
                     /locus_tag="TVW11_000979"
     CDS             complement(15751..16818)
                     /gene="pepA"
                     /locus_tag="TVW11_000979"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1365085.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPAHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            17163..17510
                     /locus_tag="TVW11_000980"
     CDS             17163..17510
                     /locus_tag="TVW11_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1365086.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            17507..17824
                     /locus_tag="TVW11_000981"
     CDS             17507..17824
                     /locus_tag="TVW11_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1365087.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            17839..18465
                     /locus_tag="TVW11_000982"
     CDS             17839..18465
                     /locus_tag="TVW11_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1365088.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(18768..19481)
                     /locus_tag="TVW11_000983"
     CDS             complement(18768..19481)
                     /locus_tag="TVW11_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1365089.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            19593..19988
                     /locus_tag="TVW11_000984"
     CDS             19593..19988
                     /locus_tag="TVW11_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1365090.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            20435..21409
                     /locus_tag="TVW11_000985"
     CDS             20435..21409
                     /locus_tag="TVW11_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1365091.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            21427..22389
                     /locus_tag="TVW11_000986"
     CDS             21427..22389
                     /locus_tag="TVW11_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1365092.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            22504..23388
                     /locus_tag="TVW11_000987"
     CDS             22504..23388
                     /locus_tag="TVW11_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365093.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICAAGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            23397..24200
                     /locus_tag="TVW11_000988"
     CDS             23397..24200
                     /locus_tag="TVW11_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1365094.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(24299..25303)
                     /locus_tag="TVW11_000989"
     CDS             complement(24299..25303)
                     /locus_tag="TVW11_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365095.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(25589..26230)
                     /locus_tag="TVW11_000990"
                     /pseudo
     CDS             complement(25589..26230)
                     /locus_tag="TVW11_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(26251..27228)
                     /gene="dusB"
                     /locus_tag="TVW11_000991"
     CDS             complement(26251..27228)
                     /gene="dusB"
                     /locus_tag="TVW11_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1365096.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(27215..28087)
                     /gene="hslO"
                     /locus_tag="TVW11_000992"
     CDS             complement(27215..28087)
                     /gene="hslO"
                     /locus_tag="TVW11_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1365097.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(28337..>29509)
                     /locus_tag="TVW11_000993"
     CDS             complement(28337..>29509)
                     /locus_tag="TVW11_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1365098.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILK
                     EKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT         8429 a         5363 c         6848 g         8869 t
ORIGIN      
        1 attcatctaa aattatttca atgcttcatg gatgattctt tttttgttaa aatgagattg
       61 aatgtcgaat agataagtag gtgggaaaat gaaagctgaa ctcattgcgg tgggaaccga
      121 gattctgact ggtcagattg tgaataccaa tgctcaattt ttatcagaaa aaatggcgga
      181 gcttggtatt gatgtttatt ttcaaacagc tgtaggagat aatgaagagc gtttgctttc
      241 tgttattgat attgctagcc agcgaagtga tttagtgatt ttatgtggtg gtcttggtcc
      301 aacagatgat gatctaacga agcagacctt agctaagtat ctgggaaaag ctttggtctt
      361 tgatgagcag gcaggtcaaa aattagatgc tttttttgca catcgtaagc aggctgctag
      421 gacaccaaat aaccaacgtc aggcgcagct gattgaaggc tctattgctt tgcaaaatca
      481 aacaggactt gcagtaggtg ggttaataac tgtagatagg gtaacctatg ttgtcttacc
      541 agggcctcca agtgagctaa agcctatggt aaaaaatgag ctggtgcccc ttctttcagc
      601 tagtcatgcc agtctatatt caagagtgct gcgttttttt ggcattggtg aaagtcaact
      661 ggtgactgct ctggaggatt tgattaagca tcaaacagat cctactattg ctccttatgc
      721 aaagaccggc gaggtaacac tgcgactatc cacaaaggct gacaaccaag cattagctga
      781 tgaaaggctg aatcgactag aggcgcagct cttatccata agaactgtag ataatcaacc
      841 cttacggcgt ttgctttatg gctatgggga ggataattcc ttggcgcgtg agacctttga
      901 gctattgaag cgaagtggta agacgataac agcagctgaa agcttaacag caggactgtt
      961 tcaagctcag ttaactgatt ttgcgggagc ttcacaggtg tttaacggtg gctttatcac
     1021 ctacagcatt gaagaaaaag caagaatgct tggcattcca ttgggtgagc tacaaaggca
     1081 tggtgttgtg agctctttta cagctgagca aatggctgca caggcacgct gcttgaccaa
     1141 ttcagatatc ggtattggtc taacaggtgt tgctggtcca gaggcactcg agggacagcc
     1201 agcaggaaca gttttcattg gccttgccac taagaataag gtagaatctc ttaaagttgt
     1261 tataggaggc cgtagccgtt tggacgtgcg gtatattgct gccctatatg cttttaatat
     1321 ggttcgtaaa actttattaa aatcagagaa tttgctataa ttaggatagt gtattttagg
     1381 aaattagtaa ctagacagat gtgaggttat gctgtttatt gcttgctagt cagcctaaat
     1441 agaggagaaa atattggcaa aaaaagttaa aaaaaatgaa gaaatcacca aaaaatttgg
     1501 tgatgaacgt cgtaaagcac ttgatgatgc gttaaagaac atcgaaaaag attttggtaa
     1561 gggtgcggtt atgcgccttg gtgagcgtgc agagcaaaag gttcaggtga tgagttcagg
     1621 cagtcttgct ttagacattg cgcttggagc aggtggctat cctaaagggc gtattattga
     1681 aatctatgga ccagagtctt ctggtaaaac aacagttgcc ctgcatgcag tagcgcaggc
     1741 tcaaaaagaa ggtggtattg cagccttcat tgatgcggag catgccttgg accctgctta
     1801 tgctgcggcg ctgggtgtta atattgatga gctgcttttg tcacagccgg attctggtga
     1861 gcaaggactt gagatagcag gtaaactgat tgattctggt gctgttgatt tggttgttgt
     1921 cgactctgtt gcagctctag tgcctcgtgc tgagattgat ggtgatattg gtgataacca
     1981 tgttggcttg caggctcgta tgatgagtca ggcgatgcgt aagctttcag cctcaatcaa
     2041 taaaaccaag acaattgcga tctttattaa ccagctgcgt gaaaaggtag gggttatgtt
     2101 tggtaatcca gagacgacac caggtggtcg tgctttgaaa ttctatgcct ctgtccgtct
     2161 ggatgttcgt ggaacaacac aaataaaagg aactggagat caaaaagaca gtagtattgg
     2221 taaggaaacc aagattaagg ttgttaagaa taaggttgct ccgccattta aggtggctga
     2281 ggttgaaatc atgtatggag aaggcatctc acgtacaggt gagctgatta aaattgcttc
     2341 agatttagac attattcaaa aggctggtgc ttggttctct tataacggtg aaaaaattgg
     2401 tcagggctct gaaaatgcca agagatattt ggctgatcac ccagagctgt ttgatgagat
     2461 tgaccataag gtgcgtgtta aatttggctt gcttgaagat actgaggaaa gtgcagctgc
     2521 agatacagtt gcagccaaag cagatgagtt ggttttagag ctagacgatg ccattgaaat
     2581 tgaggattag tgcttagtat tagattttca gataaaggtg ctaaaaaggg cttaacagcg
     2641 atcgtcaagc cctttttagc ttgtgtttaa tcaagctctg tattggtctg ctcaggagct
     2701 aggctgtacg cttggataat ttgttagctg agtttatgtt ttctttaggg attaactgtt
     2761 aagctataaa agccctagaa aaaagggact tcctacagac aagatagtgg catagtaagc
     2821 ttgcttgcaa ctagctcaat ataggatttt ggccttggtt aaagggatca taaaagaaaa
     2881 ctaaaaaata ggtccaaaga ccgatattga ttagaaaaaa actatgctac aatagaggta
     2941 tcacgagata gaaagtgaga acaacatgat aaaaatttac acgatttcaa gttgtacgag
     3001 ctgtaaaaag gctaaaacct ggctgaatgc ccataagctc ccatataaag aacagaattt
     3061 aggaaaagaa cctctttcaa gagaagaaat tttagctatt ttatcaaaga ctgaaaacgg
     3121 tgtggagagt attgtctctt ctaaaaatcg ttatgccaaa gccttaaatt gtgatattga
     3181 cgagttaagc gtaaatgagg ttattgattt gattcaggat aatccccgta ttttaaaaag
     3241 tccgattctt atcgatgaca agcgtcttca ggtgggctac aaggaagacg atattcgtgc
     3301 ctttttacct cgttctattc gtaatattga aaatgcagag gcgcgtttac gcgctgcctt
     3361 ataaaaagct ctgtcagagc tttttttaat atcctaacaa atctgaattc ttgtttattc
     3421 aataaaaata agctataata gagcgtagca cttaaagtta gaaagaaggt gtaagtatgg
     3481 gatttacaga tgaaacagtc cgctttaatt tagacgatgg tgataaaaag cagattagcg
     3541 aaacgctgac ggcagtttat cattcactag atgaaaaagg ctacaatccg attaatcaaa
     3601 ttgtaggtta tgtactaagc ggggacccag cttatgttcc tcgttacaat gatgctcgca
     3661 accaaattcg taaatatgag cgcgatgaga tcgtagaaga gcttgttcgc tattatttgc
     3721 aaggaaatgg aatagatatt agatgagaat aatgggactt gatgtcggtt ctaagaccgt
     3781 cggtgtggca attagtgatc cacttggttt tactgcccaa ggactagaga ttattaggat
     3841 caatgaagat aaacaggatt ttggctttga tagattagct gagcttgtta agcaatatca
     3901 ggttgatcga tttgtcattg gcttgccaaa gaatatgaat aacactagtg gcccacgtgt
     3961 tgaagcaagt aaggcttatg gagataagat tgaggagctc tttcacattc cggtttctta
     4021 tcaagatgag cgcttgacaa ctgttgaggc agagcgtatg ttgattgagc aggcagacat
     4081 cagtcgtggt aaacgtaaaa aagtaatcga taagctggct gcgcagctga ttttacagaa
     4141 ttatttagat tgtaactatt aaggagaaca gatgacacat aatcatgatc acgaacacga
     4201 agtcattaca cttgtcgatg agcaaggaaa tgaagcattg tttgaaattt tattaaccat
     4261 cgatggacgt gaagaattcg gtaaaaacta tgttttacta gttcctgctg gttcgcaaga
     4321 ggatgaatca ggagaggttg agattcaggc ctattcattt acagaaaatg aagacggaac
     4381 agagggtgat ttacagccaa ttccagagga ttcagacgct gagtgggata tgattgagga
     4441 agtctttaat agcttcttag acgaagagta acaacctgag gcattagctt taaaataata
     4501 aatagcctag aatcttggtg ctagcagcat gggttttagg ctatttttat ggtttatcag
     4561 acagtaggag tgatagctat ttctatgacc tctaaatagc ctactgttaa gagtgttttt
     4621 agggtcttgt agatgttgca atagcctgta atttcgttga agttacttgc tgttgtcttt
     4681 tttagtttaa gccttaacaa agcttatagg aaatgactca acttagcaca gcataagccg
     4741 cttattttga taagtaaaga aatagccaat agctactttt agcttaaagc tgatcattac
     4801 cagtaccctt agcttttctg ggtattattt cgaataatct taatgggggt gattttatca
     4861 aaagactcag tcaagaagaa aaaagctttc taaagcatta taggctaaag acactgcacc
     4921 gctttaaaga gctgctgact tatgccagca tttgtcataa attgactaaa taatagattt
     4981 tgctatactt gtaatatgac atgtcaagga gaaacacatt gagtcaatta catcaagaag
     5041 ttatgctgga aaaggtcaat tatttggtga aagaccaccc atcgtcacat acgactaagt
     5101 atgacatgaa ggtccctagt ttatataaat tttatatctt tttctttagc atcatagcga
     5161 gcttgcttac ggttgcggtt cctttttttg cagatactgc aaatagcgtt cagtcacaaa
     5221 atttatacat cggaatgatg ttgactaaag gtcagattcc atatagtgac ttgtttacaa
     5281 caggaggctt tctgtttttt gtgctcatag ctttgagcta tcacttggga acaacggtat
     5341 ggttggtact tgttcaagcg ctgtgctttt atttgacagg tgtttatttc tataaattaa
     5401 tccattatgt gacaggtatt cagaaggtgg ctttaggttt tacagctatc tattacctat
     5461 tgtctattag tcttggattt ggtggcttat atgcgatcca gcttgccctg ccttttgtct
     5521 tggtatcgct ttggttttta accaagtatt ttgctggctt ggtaaaggac gaggccttta
     5581 ttctctttgg ctttgcagcg gcaatagcca tgctaattga gcctaggacg cttctttttt
     5641 ggctgcttgc ctgcattgcg attattgctt ataatgtgtc tcaaaagcat ttcgctcgag
     5701 gcttttatca gctgttagca gctatttttg gaatgctttt ggtgttttat acagcaggct
     5761 attttatcct caatttacag attttgagtc cttatttgga gcaggcgctt gtttatccgt
     5821 ttagttattt tgtgacaggt gatttatcgc tgattctcgg tttaacagtc caattaggac
     5881 ttgttcttgg cttgggactg ttaacggggc tgctgacgtt tatgaagcag cctaagctag
     5941 agtctgatct tgctatgaaa tggctactag tctttgttgt gtttagctat gctggtattg
     6001 cggctatatc gcatgatttt catacttatc acctactgcc tttactgcct tatgctttga
     6061 tcttgctatc aagctctgtt ggccgacaat atgaggcagg acttaggatg gttagtcatc
     6121 gtcgtcgtaa ggggaaaaat ggtgcgagac gggttattgc tatttatcta aataagcatt
     6181 tctacgtgcc agcaatcata atgctaggag cggtttttgg cacagcttat cagtatgtga
     6241 ccagctctgc tattaatcaa gagcgttctc agattgctca ctatctaaga cagaggctaa
     6301 cggaggacca acccatctat gtatgggacg atacgtcaaa aatttacctg gaaacgcagg
     6361 ccaagtcagc ttcacagttt gcctcaccct ttgttaatct gaaaaaagag agtcatcaac
     6421 agatgttaga ggatgagcta ctacagaata aggcagtcta tattgtggtc aacaagcaaa
     6481 aagcattacc aaaggcagtc aagaaaatag tgacagctaa ttataaaatt gacagaaaga
     6541 ttgatgttaa gggctttagc ctatatcaga aaaaataaat aaaatcaata tattgtgttg
     6601 gtataaaaaa acttaacaca atatattgat ttttttgtgt ggcgtgatat aatagtcgag
     6661 taaggagata ggacatgata acattagaaa aagacaaagt tattgttcag ccagctatta
     6721 aggttattaa aagagatgga cgcttggtta attttgatgc aacaaagatc tacagtgcgc
     6781 tgttaaaagc aagcatgaag gtaacacgca tgtcaccgct cgttgaagca aagctagaag
     6841 ctatttctga acgcgttatt gcagaaatta tcgagcgatt tcctacaaat attaaaattt
     6901 atgaaattca aaatattgtt gagcatgagc tattagccgc taatgaatat gctattgcta
     6961 aggaatacat caattataga acccagcgtg actttgcccg ctcgcaggcg acagatatta
     7021 atttttctat tgataagctc attcacaagg atcagacagt agtcaatgag aatgccaata
     7081 aggatagtga tgttttcaat acccagcgcg atttgacagc tgggattgtt ggtaagtcta
     7141 tcggtttgaa gctgctgcca gcgcatgttg ctaatgccca ccaaaaaggt gatattcact
     7201 accatgattt agattatagt ccttatacgc caatgacaaa ctgttgtttg attgatttta
     7261 agggaatgct ggcaaatggc tttaaaattg ggaacgctga ggttgaaagt cctaagtcta
     7321 ttcaaacagc aacagctcaa atttcacaaa tcattgctaa tgtggcctcc agtcagtacg
     7381 gtggctgtac agccgatcgt attgatgagt ttttggcacc atatgctgag ctaaatttca
     7441 aaaagcatat ggctgacgct gaaaaatggg ttattgagga gctgcgggaa agttacgcct
     7501 ttgaaaaaac aaaaaaagac atttatgatg ccatgcagtc tctagagtat gagatcaaca
     7561 cgttatttac ctcaaacggt cagaccccct ttacctcatt gggatttggt ctagggacct
     7621 cttggtttga gcgtgagatt caaaaggcta ttttaacgat tagaattaat ggcttaggca
     7681 gcgagcaccg tacggcaatc ttccctaagc tcatctttac ggtcaagcgt gggctcaatt
     7741 tagagccaga ctcaccaaac tatgatatta agaccttagc cttggaatgt gccacaaagc
     7801 gcatgtatcc agatatgtta tcttatgata agattattga gctgacagga tcctttaagt
     7861 caccaatggg ctgtcgctct ttccttcaag gctggaagga tgaacagggg caagatgtta
     7921 cctcagggcg tatgaacctt ggggttgtaa ccatgaattt acctcgtatt gctatggaat
     7981 caaatggcga tatggataaa ttctgggagc tgtttaacga acgattacac atttgtaagg
     8041 acgctcttgt ttatcgtgta gagcgcgtta aggaggcaac gccagccaat gctcctattc
     8101 tttaccaata tggagccttt ggcaagcggc tagctaagac tggcaatgtt gatgagctct
     8161 ttaacaatcg ccgcgcaact gtatcattgg gttacattgg cttatatgag gtagcaaccg
     8221 tattttacgg tgggcaatgg gagcacaacc aagaggccaa agactttaca atcactattg
     8281 ttaaggaaat gaaaaaggct tgcgagactt ggtcagatga atatggctat catttctctg
     8341 tttactcaac accatcagaa agcttgacag atcgtttttg ccgcctagat actgacaaat
     8401 ttggcgttgt tgctgatatt acagataaag aatactatac taattcattc cactatgatg
     8461 ttcgtaaaaa tccaacacct tttgagaagc tagattttga aaaggcttat ccagcagccg
     8521 gtgcttcagg tggctttatc cattactgtg agtaccctgt tttgcagcaa aatcccaagg
     8581 ccttggaagc tgtttgggac tatgcttatg atcgtgtggg ctacctaggc acaaatacgc
     8641 caattgataa gtgctatgaa tgccattttg agggagattt caccccaaca gagcgaggct
     8701 ttacttgtcc aaattgtgga aacaatgacc ctaagacagt agatgtggtt aaaagaacct
     8761 gtggttattt aggaaaccct caggctcgtc caatggtcaa tggtcgtcat aaggaaatct
     8821 ctgctcgtgt caagcacatg aacggatcaa ccatcaagta tccggggata taagccttgg
     8881 agaataatct cattacacct atatcattgt aaaggattgc ttcatgcaag cagtccttta
     8941 gttatcaaga caggtctgta acaaagaaag ggagaaacat gggaaaatac cagttagatt
     9001 ataagggaat gcagcaagta gagaggtttc atgagaaaca ttctgttgca aaaacagaca
     9061 aaaagtctcg agtacagcag cttagagcac aatttttaga aaaagcaaag caatcaaaga
     9121 aataatggca cactcagtaa aggcggtgaa gaatgctaga tattggaatt gttgggttag
     9181 gcgctatttc acaaaaggcc tatttaccct atatgcgtca attaagagga atcaattggc
     9241 atttatctac tagaaatgcg ttagtccgcc aggaggtggg tcagcttttt ggttgcgcaa
     9301 ggctttacag cactgtcaat gagttacttg aggctaagtt agatggtgtg tttatccatg
     9361 cagccactaa ggctcattta gagctggcta gtttgttttt acaaaaagga attccagttt
     9421 acatggataa gcctttgacg gaggatttct ttagcacgca ggctctttat caattagcag
     9481 ataagcacaa tacctttttg atggcagact ttaatagacg ctttgcacct ggtgtcaaga
     9541 agttgtcaac cctgtcaacc aaacgtaaag ttgttgttga gaaaaatgat attaatagac
     9601 caggtgacaa acagtttaag ctttttgact tctttataca ccctttagat acagctttat
     9661 ttttagttga taggaggctt gttgcaggct attttcatta tcagctgact gataatgatt
     9721 tgctaagtca ggttagtgta accttaagga cagaacagac tattatttca gcagctatga
     9781 atctacagtc aggtagcagg cgtgaggtga tggaggttca gacacctaaa gagacctatc
     9841 acctagaaaa tctagagacc ttgcgagctt atcgaggggt tgatcaagag atcaagggat
     9901 ttagtgcttg ggatactacc ttatctaaac gaggctttga ggctattgtg gattcttttt
     9961 tacaggctgt caaggatggt gttaaccctg tcaagccaga gacaagtctg ttgagtcact
    10021 ggatttgtca ccaaatttgt caatctcatg aagctgatgg catattagat gtttctcttc
    10081 ccttataaag gagtgataat atgaagctac gaagacctaa aaagcaagat gaagcgtctg
    10141 ttttagaaat gatggcagag tttgaagact atcagtctcc tcatgatggt ggtttttgga
    10201 acgctgagca ttttgattat gaaaaatggt tggaatctaa tgctctgatg gaggctggct
    10261 tagctatccc tgagaattgg gtgcctgcca tacagctcgt tgcctttgct gatcaacagg
    10321 ctattggatt tgtcaatgta cgcttgagat taaacgaaca gctactggta aaaggtgggc
    10381 atattggtta ttctgttaga cctagccagc gtggaaaggg ctatgcaaag ctgatgctaa
    10441 aggaagcctt gcagcttgct cgtcaaaagg gcattcgtga ggttttagtg acttgtcatt
    10501 gcagcaatag tgctagtcgg tctgttattt tagctaatgg tggtcagctg aaggattgca
    10561 ataagggtat tgaacgctat tggataaaag cataagaggc aataatgaag gaaaactgtt
    10621 ggaattctcc caaaccaaaa gaatggacat cagaggcatt aagccaagga cgcgttattg
    10681 attataaggc atttaatttt gtagatgggg agggagtgcg aaactcactt tatgtttcag
    10741 gctgcatgtt ccattgtaag ggctgctata acgcagcaac ctggtctttt aaggcgggta
    10801 ttccttatac gaaagagctt gaggagcaaa ttatgactga tcttgcaaag ccctatgttc
    10861 aaggtttgac acttttgggc ggtgagccct ttttgaatac gggaatattg attcctttga
    10921 ttaagcgtat cagaaaagag ctgccagaaa aggatatttg gtcttggaca ggctatacct
    10981 gggaggaaat gatggaagaa acccaggata agctagagct gttaagcatg attgatattt
    11041 tagttgatgg ccgctttgat atcaccaaaa agaatctgat gctgcaattt cgtggatcca
    11101 gtaatcagcg tatcatcgat gttaaaaagt cactggctgc tggagaggtg gttatttggg
    11161 ataagctaaa tgatggtgat cagtcctttg agcaaatgag ccgcgatgat ttgatttagt
    11221 agagacttat caacatcact agacttgaaa gctaataatg aaagcatgat tttaggctcc
    11281 tgtggtcttg cttaaccaat ctaataaggg gttttcccca cattatcctc atacttatcc
    11341 acaggttgtg aataacctgt tggtttgtgg ataaaaaaga gaattaaggg gttctttaat
    11401 tctctaggcc tgaaaaaggg ttctttttga tgttttttct taaaagaaag agaggcaagt
    11461 gacctctctt gaaatagtat acttaggctt taagcctagc tttcaatatc tctgaatgtc
    11521 tgattttctt aggagtcagg cattttttaa tggcgatggg aagtacggct tgtgggtcgc
    11581 tttgtgtgct aagaggcttt ctgagctgct atatgtcaat gattggtgat gtgacagctg
    11641 aggcttgttc acattctgaa agcactgatg tttttcctag ctttcttttt tgatgtagta
    11701 gtaattagtt tcggttgata gctcctcatt atagcaaaag ccagcaaagc tcagctgctt
    11761 aagtgcttcc ttggtttgga cattgttttc tagacaggct gttagaaagg ctcctcgagc
    11821 tttttttgaa atggttgaat gcgtcttgag ctgtcctgat ctttcctcca taaatttggg
    11881 acttatccac agtttttgat attcctttga aaaaacatct ctaaactcgt tggataacag
    11941 agaaatgatt tgcttgtgat ctttagcaaa ctgatcgtag atagggcgcc aataatgctt
    12001 aaggctttgc ccattgatgg ttactttagt gtgaaaatca tgccggtgct ctgcgatttt
    12061 ctcatcagta gggataatgc cataaaaaga cgaggtaatg tagacctgct ttgagaggta
    12121 gtcttgctgg tctttagaga gattgtcgcg cttgagatga cggtacatga gcccattaaa
    12181 gagctgataa gcaggataag cagaactctg cccttgagct atggccttta gtctcttggc
    12241 ttccttgctt gctgcttcta tacggatgct gtaggccctt gctagctcct ctagggatag
    12301 ttcagccata gcctctaata tgggcaggct tttttgggga agctgatgtg gatagcaagg
    12361 tggaactggt ttcatttctt tagctgttgg aattaaaaaa gttaacataa gtttattgta
    12421 gtaaaggcgg caaccttctg tcaagagtgg gatacatttg gtggttatgt catatgaaac
    12481 taatttttat attttttaca ttttgattag tttttaaaaa tatagtgatt tagtgttgca
    12541 taacctctct aagtatgtta atatatactc aagtctattt gataaacaga agctcaggtc
    12601 aagtgagtgt tccacttaca ataacgcagt tgatgatggg gagactcaga ctcagactca
    12661 gactcagact cagagtcaag gaaaagaaat atagtcttgt aggattacct acagggcttt
    12721 tttctatttt gaattgagag atcaatataa ggtgatgtgc tgttttttat taccttaaac
    12781 atttggatat tggctattga caaaaagtgt aaaggaaact atactatatg tgtaaagtta
    12841 acttgacata ttggaggaac catggaaaat cggatacaag aactccgtaa gtcacgaggg
    12901 attagtcaag ctgatttggc agatatgatg tgtgtcacta ggcaaaccat tatctcctta
    12961 gagaaaggac gctataatgc gtcattagag ctggcctata aattagcgac atttttcaat
    13021 ctgactatag aagacgtttt cttgtttgaa gagaagggag aatgagatga tatttagtga
    13081 tttaagcgtc ctgctgactc aaaaaagcca gctagcctat gccaaaaggc tgaagtatat
    13141 gggctttttc gctctctgtt taggcggttt gtttttgttg ctggcctttg acgtgagact
    13201 gacgagcttt gctcagggaa tgctggtagg gcttggtagt ggtagcttat tattaggtgt
    13261 tcgtgctttt tcagattgcc tttaatcctc aaaggctgag agcctcttat attaaggctt
    13321 atgatgagcg tcatcaggta gttatcaagc tagctgctgt atcaacctta atcttattag
    13381 tggtgttgat tattggctgt ttgtgcttga atgttttttg gagtttggtt tttggcttta
    13441 gagtattttt agagatttgt ctgtatacga tcttgcttgg ttttttaggc atcaagctat
    13501 tgttagagca tatgatttag gaggcttcaa tggaaacaaa acattcagca gtaaaggtca
    13561 tcatcagtaa attaaaatgg tttggcttag ctcttcttgt gtttatgctt gagcaggctc
    13621 caacattttt gataacaaaa gaacagccaa tgtggcagac acttcttctt gtggtcattt
    13681 ttcttttgat tagtggaggt acttattacc tagctgtgaa gcttcacatt gtgggagatc
    13741 aagctattcc taagaatgac tatcgggcac tttggattgg tttgggagtg gtagctgtct
    13801 ttgttgtcaa gatgattggt ggtattctgt tgtttttgga gcatggtccg ggagccaata
    13861 cggtcaatca agctgcctta gaacaggcag gcttatctcc gattcttatg gttacgctag
    13921 ttgctattgt ggcaccaatt gtggaagaaa ttgcttttcg agggctgctt tatgggaagc
    13981 tctttggtgc agagtcttat ctgggcttga tttttagcag tatcatgttt ggcttgattc
    14041 atgtgccaac agattttggc agttggttta tctatggcgg tatggggctg gtgttaggct
    14101 ttgttttcca taaaacaaag aaggtcgaat acacgatatt gattcatttt ttgaataatg
    14161 cactagctgt tcttatcatg cttttgctgc cttatcttca gtagtactgc ttgagtaatg
    14221 aagggggtaa tgaatgaaaa atgatcgttg gattgacaaa aaatatcaac gttgggagaa
    14281 agtgtataag agacttggtc attctttact gacaatcggt gtgttggtag ggacttatgg
    14341 gatttttttg attattcaag ggaatcatca aacgggcttt ctccttttta tcctggggcc
    14401 tatactattg attgcgtcat gtctttgcta ttatgtgttt acagagccaa cgtctttacg
    14461 agaatatctg attaatagct atgatgagcg taaccgagct attcgtcaga aagcacaggc
    14521 ctactgcttt tgtctatttg cttttctctt tttgatgctt gcgatattct ttccaaatat
    14581 gacgatcaag gagctttttg ggtataatct tccgttgatt gttttcaatc tgtatgtcat
    14641 gattagagcc tgggttagta aacacatgta ggtcatgtta acacaaagga gtctagagca
    14701 agggctttga atgaaactat ttttctaaaa acgcaaaaaa tcgcgtgcag taacagatta
    14761 ggccatgtta ctgcatgcga ttttgttgtt tcaaacgtga gctcagaatg acatatcctt
    14821 tttagaaaga ataggtattt agggctgtct tgagctagtc ttaggtaatg agcttggagc
    14881 tcattggtga tggttaggat aggtctttag cttttttgat cgttgtgtca atggcagagc
    14941 agacagaatg tgtcaggcct gttttttcaa gatccatcaa gcctgcaatg gttgtgccgc
    15001 cgggactgca gatcttatca atcaaatcat ggggactatc tgtgctgact agcaggttct
    15061 tggcgctagc taggacagtt tgactaacga tactaagggc cttgtcttta ggcagtccat
    15121 ttttgactcc ggcctttgcc atagcttcga tgaaaaggta aagataagca ggacttgacc
    15181 ctgctagagc agtaaaggta tcaaaatcct tttcagctat ttcaaaggtt gttccaaagc
    15241 tgttggttag ctctttagca gtagctaata aatcagcagt tactaagtca ttaccagtca
    15301 aagcagtggt gctttggaga atttgagcat tcatatttgg catgatacgt aggagtggca
    15361 aatgagagct tgttaattga gctagtctgt ctaaggaaat accagcagcc attgacatga
    15421 taggctgttt gaactgtaga gggctaagaa cagtctcaaa gagctgtggc ttgatcccta
    15481 gaatgatgaa gtcaacctga tcgatcagct cttggtgaga ttgggcgtag cttaggtgca
    15541 attggccagc aatttcttta gagcgagcta aggatgagcc tgagatgatt agctcgtgtg
    15601 gtgtgtgtgt taggccttga atgatagcag ttgccatttt gccaacaccg ataaatccaa
    15661 ttttcataat aatgttccta aaaatgaata aaggctcaat aggctagagt gctcattgaa
    15721 ccttagattc gcattttagc cttatccttc ctagtatttc ttgattaaat caactgttga
    15781 gcggtcaagc tttttgacaa tggcttgcaa aaaggcctgt gcttctacga aatcatctaa
    15841 ggcgtacaag ctctgatgtg agtgaatgta gcgagcgcag acaccgattg tggttgaagg
    15901 gataccgcca tttttaaggt gagcagcacc ggcgtctgta ccgcctttac cacaataata
    15961 ttggaaggca accccagcct cctcagcggt ggttaatagg aagtctcgca tgttcttaag
    16021 catgatgtgt ccgggatcgt aaaagcgtag aagggttcca tcaccaatat gggcaggatt
    16081 gccataaata tcaccagcag gtgagcaatc aacagcaaag aaaagctcag gatcaaatgt
    16141 agtggctgac acatgggcac cacgaagccc gacttcttct tggacatttg ctccagcaat
    16201 aagggtgttg tgaagtgtct ggtcttttag ggcttctagc agctcagtga ccatgagaac
    16261 accatagcgg ttgtcccagg cctttgagat gatattcttt ttattggcag ttaaaatggt
    16321 ttcagactgc ggtacaataa tatctcctgg tgtgatgcca aagctttcgg cttcagtttt
    16381 gtctgtaaag ccaccatcaa aaacaatatc tgaaaccgct ggcagactag cagcaccatt
    16441 tgccccgcgc agaaaatggg gaggaactga gcctgaaata acaggaatgg cttggccagc
    16501 gcgagtgtat aaggtaaagc gctgtgagct aacaactagt ggattccagc cgccaatttc
    16561 aacaacccgc agtgttccat cagctttaat ctcgctcacc ataaagccaa cctcgtccat
    16621 gtgagccgca acaagaatgc gaggagcttg atccgccttg ctttctttta tcccaaatat
    16681 gccgccaagt ccatcaacct ccactcggtc aacaagcggc gtgatcttag cgcgtaagta
    16741 atcccgaaca gtgtgctcgt agccggcgat gccgtctaat tcagtaactt ctttaatttt
    16801 tgaaaataaa tcaatcattt gtatactcca tttgtcatgt aagattaaag gtatcacgtc
    16861 tgcctctatt ctatcatttt ttagtgaaga atgggaaaca gcttgagcat aggaaaagag
    16921 tttgggagat taggtgtgtc tttcttgctt gataagctgc ttattatcag tttgattcag
    16981 atgagataac tgctggtatt gatggaatga aacagctatg cacaacagcc ttgacaagga
    17041 tcgacaggcc tgagctgtct tatgctatca attgcactta ggtagagcag tagcctgata
    17101 ttgatgtgat tagttgctct tgtcaggtgg tttattagta tttcctaaag tgtcagctag
    17161 tcttggctga gattgttagc ttttgctcta gcctattatt ccctttttgt gataaaatga
    17221 aaggtatgaa tggaaaaaag acacgtattg tttcaggatt aattggactg ggtctgctag
    17281 ccggcttggg attgaggctt aaggaagtct atcaagaaag agagcgtcag agagtattgg
    17341 ttgaattgcg cgcctttttc tcagccttag gagagattga ggtcttgtac atcaactcct
    17401 ttagctcaaa gcgtgatgat gtcactggtg gccttgtcat gacagatggt aagacctata
    17461 cttaccatta ccacaaagga agtattgatt ttaaagagga tttgacatga ttattccaac
    17521 atctaaggaa gaacttgcta ggctaattga gacagagcct aggctggttt tgttttttac
    17581 agcagattgg tgtccggatt gccagtatat ctatcctgta atgcctgagc tagaggctga
    17641 aaacccggat atgacctttg tccgccttga tcgcgatgat tttatcgatt tagcgcagga
    17701 ttggcaaatt tttggcattc caagctttct tgttatggaa aaggggcagg agaagggccg
    17761 tttggtcaat agattacgaa aaacaaaggc tgagattagt gactttctag cagcctatca
    17821 ctaagaggag aaaatgagat gatttttgca tataataaag agcaggtcgg tgatgttttg
    17881 atggtgatac tagaggataa aaaagacatc aagcgacagg ttgagcgtaa ggggagagta
    17941 gcgcgtgttt ttgcagaaga gacagggcaa acccttgctt ggaatatttt tgaggcgtca
    18001 gccttaatcg ctgttgaggg aaatgggcag gttttcttgt ctgaggagga gttagcgatt
    18061 ttaaatgcgg agcttgctca agaagggttt actgaacgat tagaggctag cccagcccct
    18121 gtttttgttg tggggcaaat cattgagatg attcctcacc cagatagtga tcatttgaat
    18181 atctgtcagg tacagattgc tcctgataag gctgtgcaaa tcgttgcagg agcacctaat
    18241 gctgctgttg ggttaaaaac aattgttgcc ttgccaggtg ctatgatgcc aagtggcagc
    18301 cttatttttc caggaaagct tcgtgggaag gaaagctttg gtatgatgtg ttctccacgc
    18361 gaattggcct tgccaaatgc tccacaaaag cgtggtatta ttgagcttgg tgatgctgca
    18421 gcggttggtg aagcctttga tcctgctaag cattggcaga gctagcagga cttgatcagc
    18481 attaaaatgg tgtttagtcc ttcttttgct tggtgaaaag cctttggacc ttgagccatg
    18541 cagtgctttt tgctggtctg tgactgtctt tagcttcagg atcgaagcat tagagtagct
    18601 gcttaactta ttgtcagcgc tgttgattgc agtagcgcta tgcttgtgac aagtgaaggc
    18661 aaagcctatc aatgcccttg gctagggcta aaaattgtct ttagagtcac ttttgaggtg
    18721 agtagctcgc taatttcggt attgaacggt gcttaggtac cgttttttta agctttgctg
    18781 agtgtgacat gctgaaaaaa ggccatgtct ttatatggct tttggtcaca gatggctaat
    18841 tcaatcgtcc gcaacacttc cagccaatca ggcttagctt taacctcatt tggttgaagt
    18901 ccgtagcatg tccgcagtcc acgatagcct tggagcttca aatcggtctt tctgagtaag
    18961 tcatcaatac tgtaggtctg acctgctgca aaggataaac tttcaaaggc ttgtccattt
    19021 agcacattaa gtgccttgtc atagtcgtgt tcaaaaataa cagagtggag aacttttccg
    19081 acttgattgt gcttgatgag tgatagctgc cctttaggct tcaatagacg ttccatctga
    19141 gctaggtaga tcgcatgctc ttttggggcg atatattcta agacattgtg gcatatgatc
    19201 atatcaaagg cttgatcagg cagtttttct agcgcttcta atgaaccttt tattttatga
    19261 atgctttctt gcttttgggc aaataatagg tcaggatttg gctcaattgc agttacttca
    19321 ttctggacgg ctaatgcctc tgctgtgatg caaaagcctg ctccgaaatc taaaatagtc
    19381 ttgcctgcta tggggcctaa ttgggcaaag atcaaatcat acatgagctt tccccagggc
    19441 cttgtgagca tgtcttgata ggctttaaga ttaatagtca ttatctagtt ttcctttctt
    19501 tagctgctgt gagctattgg caggatttct aaacttcaca gcttgtcctt attttaccat
    19561 gttttacgaa taataagata aggaggtatg acatgtacaa taaagtaatc ttgataggcc
    19621 gtttagtggc caagccagaa ttaaacaaga cattaacgga taagcaggtc gttcgattta
    19681 ccttagcagt taatcgtcgg tttaagacga cgactggtga gcgtgaggtg gattttatca
    19741 atgctgttgc ttggggaggt ttggctgaaa ccttggcttc ctatgctagc aaggggagtc
    19801 tgctgtcact tgatggcgag cttcgcacac gaaaatatga caaggcgggt cagactcatt
    19861 ttgtgacaga ggttttgtgt cattcttttc aattgctgga aagtcgagcg caacgagcta
    19921 tacgtgaaaa caacgctgct aatgatttga ttgatttggc tttagaggag gaaaagcttc
    19981 ccttttaaag acagctgcta gcttactgtc gctaagggag tcagacacta gcattgtgta
    20041 tgctagagat ctcaacataa tctaaaaaat gacaacgatt ctaaaaaaaa tcttgacacg
    20101 tcttagaaaa aggtttacaa tgtatgacaa ttaaaatgaa agaaaacagg aggtgctggt
    20161 atggtagcag ttagcacagc tcagacgatg actaagcgtt attactttag cttctttaga
    20221 tagtgtttgt agacatgagc gcatggatac aaacacactg aacgttatgt ttgtatctat
    20281 ggggctaagg gctatttgag ttgtttgtcc acatagatga tatctcttct aagtggacac
    20341 catacagcat gtattttgtt atctcatgat acctgtatag gaccatttag attatctaga
    20401 tggtcttatt tttatgcaag aaagaggaaa tgacatgaga tttaaacagt tatccttaac
    20461 agcctttata gggcttttgg caatgctgct aacggcttgt cgacaagaaa ccaaccaaac
    20521 acatcaagct gctagagttg ggattattca atatgctgag cactcagccc tagatgctgc
    20581 gcgtgagggt tttattgagg cgcttgagca gggcggcttt agagagggga agaacctgac
    20641 cattacaacc aaaaatgcac agggtgatca ggctaacctg caaacaatgg tggagcagct
    20701 ggcgggtaag aacgatttgc agcttgcgat cgcaacgccg gcagcgcagg cgcttttaaa
    20761 tatggactca gagacaccag ctgtatttac agcggtaaca gatcctgtct cagcaggtct
    20821 ggttgataca ttagctaagc ctggtgggaa tatgacaggc tctacagatg cgactgatgt
    20881 tgagaatcag attgatttgt tgaccaaggc gctgcctcaa gctaggacag ttgggatttt
    20941 ctacaattca agcgaggtga attcggagat acaggctaag aaggccaaga gggagcttga
    21001 gaaaaaaggc ttaaaggtcc ttatgaaaac cgtaaccact actaatgatg tgcagcaggt
    21061 tatgacaagc ttggctagtc aggttgacgc tgtttacctg ccaacagata atacggttgc
    21121 ctcaacagct actactattg gggatatttt aaaggaggcc aaaattcctt caatgggaag
    21181 cgatgctgct tacctgagtg ctgttttgtt cacctcaggt gttgattacc atgctattgg
    21241 catgcaggct ggtcagcagg cggtagatat tttaaagggt aaaaaaccag caagcattca
    21301 ggttgctaag cctcaaaagg caagcattgc tgttaatgat gatatggcaa gacttctggg
    21361 cattgacccc gaggtgatca aggctcttgc aagtaacgga gccaactagc gttttaggag
    21421 gaaggtatga aaaaaggaag ctatttaata ctgttagtgc ttgcaggctt cgttttggtg
    21481 gcttgtcgtt cgacagctag tcctcgtaag gttaaccaat ctcatgttaa catcggtatt
    21541 ttacaataca tggaacatga ttcgctgacg gcagctcgtc gaggctttga agcgcaatta
    21601 aaggcagcgg gctatactaa gggagacaag ctgagccttc attatcaaaa tgcacagggc
    21661 gaccaagcta atttacagac gatttcagag cagctagtga agcaaaatga tttgatcttg
    21721 gcgattgcga caccggcagc gcaagcctta gcgaccgtct catcagatag accaattgtt
    21781 tttacagcag taacagatcc tatctcagca ggcttagtgg ataggatcaa aaagcctggt
    21841 ggcttgataa caggaacaag tgaccaggcg ccgattgcaa agcaaattga cttgttagcc
    21901 caagccttgc cagaggccaa aactattggc attttataca cagctagtga acgtaatgct
    21961 gaggtgcagg taaaggaagc tgaaacgcta ctgaccaagg ttggttatag ggttattaaa
    22021 aagggaattg ccacttcaaa tgatgtgcaa gatactgctg caagcttgat gagagcagta
    22081 gacgcgcttt ttgtaccgac agataatacc gttgcttcaa ccatgacaat gctgggtgag
    22141 ctgtcattgg ctaataaggt tccaattatt ggtggctcaa cggatatggt tgatgcaggt
    22201 gggctcttga cctatggtat cgactacgag agccttggta gacaggctgg agaaatggcc
    22261 attaagattt taagaggaca ggatccagca agcctagcag tggagtaccc aaaaacagtc
    22321 aagctacata tcaatcaagc aatggcagac aagctagcga ttgatacttc cacattatca
    22381 gttgactaaa ttgctaggtt aaaggctaaa tgactgatct ctagccagct ggctaaatga
    22441 caaagtctta accagttagc ttagcttact attaacgatt catatgacaa aaaaggagaa
    22501 atcatgtcac tcattttatc gagcttatca cagggcttat tgtggtctat tatggcaatt
    22561 ggtgtttacc tgacatttcg tattttagat attgccgatt taactgcaga aggttcctat
    22621 ccgcttgggg cagctatttg tgcagcgggt attgtatcag gtgtttctcc cttgctggct
    22681 acgtttttag cttttattgg aggcttgctg gcaggccttg tctcaggatt agttcacacc
    22741 aaattaaaaa taccagcctt actaacagga attatcactc tgacaggctt gtattctgtg
    22801 aatctaaagg tgctaggaag agccaatgtg gctttattac gtcaaagaac tttagttacc
    22861 cagctctatg atctaggctt taccaagctt gcagcggtgc taattatggg ctttgtcttt
    22921 gtgaccattg tgattttttt attagccctg ctgatgaaaa ctcagcttgg cctagctctg
    22981 cgatcgaccg gagacaataa tccaatgagt gaagccaatg gtatcaaaac agatcagatg
    23041 aaaatcatgg ggtatatgct atctaacggt ttgattgccc tatgtggtgc cttgctttgt
    23101 cagaataatg gctatgcaga tttaaatgct ggtgttggga caattgttat tgggctggct
    23161 tcgattatca ttgctgaggt gatgattagg cagctaagca ttggctggcg cttagcttcc
    23221 attgttttag gctctattgt ttatcgctta attattctag ctatcctagc cattcccggt
    23281 atggatgcag atttggttaa gcttttttca gccatgctat tggcagctgt tctttttgtg
    23341 ccagaattac agcaaaggct tcgccttcga aaaacaagtt taggatagga gaaatcatgt
    23401 cagcaatatt atcaattaag gctattcaca aaacatttga agcaggtacg attaacgaaa
    23461 atcatgtctt gagaggctta tctttggaca ttgaggaggg ggattttatc tcggttatcg
    23521 gtgggaatgg cgctggaaaa tccacattaa tgaatactct agcaggcact ctggcttttg
    23581 atcagggcga tattctttta gagggaaaat caatcaagca tttatcagcc gctaagcgtg
    23641 ccaaggacat cagtcgagtg tttcaagacc ctaagatggg aaccgcttca cgcttgacca
    23701 ttgaggaaaa tatggctatt gcttaccgcc gagggaaatc aagggggcta ggctggggcg
    23761 ttaaagaaag agagcgccag atctatcgtc aggccttgca ggaattaggc ctaaatctgg
    23821 aaaaccgtct taaggccgag acacagtttt tatcaggagg gcaaagacaa gccttgaccc
    23881 tgttaatggc ttccttagca aagcctaagg tcttgttgct agatgagcat accgcagctc
    23941 ttgatcctaa gaccagtaca atggtaatgg ctttgacaaa gcagcttgtt gagacacatg
    24001 gcttgacaac cctgatgatt acccataatt tggaaaatgc tattgcttat ggtaatcgtc
    24061 tggtcatgct ccatcaaggt aatattgtgg tggatattaa gagagaagag aaggccaagc
    24121 tgacggttga ccacttgatg gcactctttc accaaaatag tggtcatacg ctccttgatg
    24181 atgcacttgt tttgggatag gctaggtgag ggttagctct gttttcaaat agcagccata
    24241 atgaaaaggc ttaaagccaa cgcttctaga aacgctagct caagccttgt tataatactt
    24301 aggagatttt tctaagagtg ataaagccat gatgacgtct attgtagtca aaggatttgt
    24361 ttcggatgcg ataagcctca ttttccacaa tttcaattgc cttattcagc tgctgaatgg
    24421 taatcgcctc atcaatctca tgaaaagcag tgctataata atcctcacta acacgttgat
    24481 tgcggtcttt ataggtattt ttatgctctg ttaaaatggc cttagcctca gcacgttttg
    24541 caatggtatc tataatacct tgaccatatg ctctagcctc ttgaaggatt gacagcatat
    24601 tgtctagaga atatgcgttt gctaagcggc tgacaaagct atcagcgacc tcaggactta
    24661 aattaatacc atctaagtga taaatcatct ctgggtgtag ctttaggtaa tactgcaatt
    24721 cgcggaacaa aagcgctgga attttcgacg aatccctata tggattgagc tgaatctcct
    24781 gactatgtag cctattgata aaatcgtcct tgaactgctt aatagcatcg tagtctgatt
    24841 tttctagctc tgctttaata ttggctagaa tctgggcgtc tgaataacga cgatagcttg
    24901 atagtgaagc agcaggccta ctagtattgg aatttcgaga agcttctgct cttctagtct
    24961 ctttgcttgg tgtttgctgc ttatttgact gagtctcctg ctcggttagt cgtagctcag
    25021 ggtgtaaacg actaatattg ttaagaaatt ggttaacctc atattctgat gaaaacttta
    25081 gcctaggtct ggccttgacc ttctcaatag ccttgtcaat aatccttttc ccgtaccttt
    25141 tgagattact gtcagactgg atcaaataaa gattaacatg taagtgatct tgactatccg
    25201 ccttagataa gctgttacca aggccaaggc ttcctaagag cgtagctagt aacagcaggt
    25261 gttttactag actacgctga acaatattgt gacgactaag cataagttat tttcccattc
    25321 tattgtaata taccagaaaa tgttatcaaa ataaagataa gatgtcaatg tcattaatgg
    25381 tggttaatct ttaattaatg gtcgttaatc tagtatatca gagagctagc ttaggctggc
    25441 agtggtcatt ctgtgcgtct tggtacgaaa tgcccaagca gatgcagctc actagaatga
    25501 tcaatagcct caacacaaag ccccttacag cttgacacaa gctgtaaggg gctttgttgt
    25561 attaacagat aactcaaatc cttgcttttt ataataaatc taaggttttt agcttgtcat
    25621 caatcatgtg cagaacggtt gccaaatcct ctgggttttg cacgaaatca agcttgtttc
    25681 catcaatctt catcttaggt gaaacgtcat attgctcata ccagcttggg tattcaccat
    25741 gtacctgatg gtaataggct tctaagtcag gattgtcgtc aacctgctca aaacgtctgc
    25801 cgcgcttttc aatgcgctct agcatcttct caaaggagac atcaatataa atcagcagat
    25861 caggccgttt ttaaggcatt ccttcaagct cctctagcat attggctaag agctcttggt
    25921 aaatttcaag ctctgtcttg gtaacatttc catttttata gttaagtgtc aagaagagct
    25981 catcttcaaa gattgagcgg tcaagaatat tattgtctgc ctggtaggct tctttaatag
    26041 atttgaagcg cttgttcaaa aagaaaattt gtagtaaaaa ggcatatttt ttagggtctt
    26101 ggtaatacag atcaagaaca ggattgttat caacagcctc gtaaaatacc tctgttccta
    26161 aatgctcacc cagtgcagca gcaagggaac tcttgcctgc gccgattgtt ccagctaata
    26221 caatcaacat gtttctcctt ctatgtagtc ttagtgtatt tgtgcaaaaa tcgtttcaac
    26281 ctcagctaag gttttagcgc gtgaaacggc actgcgaatt ttggcagcgc ctgctgtccc
    26341 tcgcaggtaa tgaggggcta acccacgaaa ttcacgaaca gcaatagctt ctcccttgag
    26401 cctgatgagg cgcttgagat ggtctttagc aatatctagc tttttagcaa agggcagctc
    26461 tggcaaaacc tctcctgtct caaagaagtg attaatttgg gtgaagagat aagggttgtt
    26521 catagctgca cggccaatca tgaccgcatc tacaccaatc tcctcaatca tgaacctagc
    26581 gtcctgaaca gttctgacat ctccatttcc aataaatgga atcctggtaa tagctcttga
    26641 gacgcgtgca agggtttcat ggtcacaggt gccagtatac atctgctcac gagtacggcc
    26701 atgcatggca agagctgaca caccagcagc ttcagcagcc aaggcattct caacagctag
    26761 tgagctgtct gcccagccgg tacgcatttt gacagtcagt ggaatgtcta aaacagaggt
    26821 tacctcctga atgatatggt aaatcttatc aggatcgcga agccacttgg cacctgcttc
    26881 atttttaacc accttgttaa caggacagcc catattgatg tcaacaatgt cagccttggt
    26941 atggctctgg ataaaatcag ccgcacgctt tagtccttca gcgtcaccgc caaatagttg
    27001 gattgacatg gggtgctcat tgtcatcaat atgaagcata tgcagggttt tttcgttatt
    27061 atagagaagt cccttttcag aaatcatttc catgacaaca aggcctgcac caaattcctt
    27121 ggcaatcgtg cgaaaggccg aattggtcac accagccata ggtgcaagca ctgtacggtg
    27181 agggatttcc acatgaccaa tcctaaaggg tgagttaagc cttgtcattg atcagcacct
    27241 ccaaatcagt ttggtcaaat tggtacttgg tgccacaaaa ttggcaaaca atttcagccc
    27301 ccttatcctc gtttagcatt gtcaacaggt cagctttagg gaggctcatt agggctgacg
    27361 caaagcgctc tcttgagcag tcacactgaa agctcagctg ctcttcagct aatcgcttgt
    27421 aaggctcttc accataaata gctgctaaca gagcgtctat atgattttcc gacgctagaa
    27481 gggttgaaat cgcaggcatt tcctgaatgc gcttctcata gtggctaatc tcttcgacag
    27541 aagctccagg cagcacctgc agcataaagc cgccagcaac cttgaccttg tcctcttgat
    27601 ctagaagcac attaaggccg acagcagatg gtgtctgctc agactctgtc aagtagtagg
    27661 ccagatcctc accaatctca ccggtaatca agggtgttgt agaggtgtag ggattgcctg
    27721 ttccatagtc cgtaattgtc acaaagtgtc cctgtcccat aaaaggacca accagtactt
    27781 ctccagttgc tgtttttttg atatcaacac cgggattttg aatatagccc ttgacatgcc
    27841 cttttgtgtc agcaacagaa ataatatgcc caaaggagga atcgccaata accttgacag
    27901 taaccttact atctcctttt tggttggcag ctagaatctg attggcaatc aaggtacgac
    27961 caagtgcaac cgttgaagat gataaggtat gatgcctttc ctgagcatat cgaacagttt
    28021 cggtgcaatc caaaacatag gccctgaagg caccggaggc agaaattgtt ttaattagtt
    28081 tatccataat ttctattata gcataatgaa caaggcttgt gctggttgct ttagaggaaa
    28141 gctgcttgaa aatagagaaa cactatttgg ttaataatag cagctctata aagccactta
    28201 aaaacagagc agtgctaaca aatggtagta ttcttgtcct tagcacgcag taagctaatc
    28261 acctaagtca gtacaatcaa acaagcatca aaaaacagct ccgataggtt gattaaagga
    28321 agaaatgata aaagagttat ttcgtaatgc tttgctgata atgagcaagg taatcatgtg
    28381 gtgtcgtatc agtgtacttt ttgaaggttt tcaaaaaatg ggtggtatcg tagaaataaa
    28441 ggagcttagc cacttctcca gctggtactc ctcttcgtaa aagtagcttg gcttcttgta
    28501 ctttttcctt caaaatatag gtctgcaacg aaatagaaga atacatttta aaaacagctc
    28561 gtaaatgtga ctctgagata taaagatgct tagcaatatc tgataccttt aattttgaat
    28621 aaaggtgctt atcgacgtaa tataaaatac tattataaat ttgctgctta tcagaaacac
    28681 ttttgttagt caatgattct gagaggctaa taatagcagc tgctcttatt tgaagcacct
    28741 taaggagatc tgtagctttt tcagttaggt tcataaaatg cttaatgcgc tcgtagtttt
    28801 tggcaacatc agtattttca gtaaagctta gttcaagcag cttaataaaa taaataatag
    28861 aaagattttt ttcagctctt aatgcgggaa tagaagagga gacgacatct gatgaaggga
    28921 tacaattgat ttcgtgcttt aatagctctg tattacccag cttgactaaa tcaataatat
    28981 gattcaaata atttaagaca gctggcacat gaaatgacgg ggtattttcc aattcgagat
    29041 tagctataat atgaggatcc tcccagatta gctgggcttc ctccagtaaa tcattaatgc
    29101 tttgctggca gctcatttca aagttggtgt caaaaaaggc atcaacagct atcaaaaggc
    29161 ttcgaatatg agaagcagga aaatgaggaa tggtagagat atagccaact agctcttttt
    29221 ttgacttatc aggatagcgc ttcaagaagc tatcggctaa ttcctcctta tagctatcct
    29281 gaaagaaaga ggtgtaaaaa ggcccaatga aaataaactt gtcaccaata ggaaacatta
    29341 gagaggattc ctcaagcgtt ccctcataac aagtgagctc agtattacta ggaatatcta
    29401 atgttttaat taattcatag taggggaatc gacgctcctc gtcatcataa gcctgaagga
    29461 gctcaagatt ttgagaaagc actaaaacag gtaattgtga taggttatg
//
LOCUS       DARYUW010000025        28825 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYUW010000025 DARYUW010000000
VERSION     DARYUW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28825
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..600)
                     /locus_tag="TVW11_000994"
     CDS             complement(<1..600)
                     /locus_tag="TVW11_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1365099.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TVW11_000995"
     CDS             1005..1649
                     /locus_tag="TVW11_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365100.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TVW11_000996"
     CDS             1654..2403
                     /locus_tag="TVW11_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1365101.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TVW11_000997"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TVW11_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1365102.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TVW11_000998"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TVW11_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1365103.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TVW11_000999"
     CDS             3125..3955
                     /locus_tag="TVW11_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365104.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TVW11_001000"
     CDS             4015..5295
                     /locus_tag="TVW11_001000"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1365105.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TVW11_001001"
     CDS             complement(5500..6792)
                     /locus_tag="TVW11_001001"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1365106.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TVW11_001002"
     CDS             complement(6782..7498)
                     /locus_tag="TVW11_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365107.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TVW11_001003"
     CDS             7752..7976
                     /locus_tag="TVW11_001003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365108.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TVW11_001004"
     CDS             7987..8907
                     /locus_tag="TVW11_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365109.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TVW11_001005"
     CDS             8894..9634
                     /locus_tag="TVW11_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365110.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TVW11_001006"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TVW11_001006"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1365111.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TVW11_001007"
     CDS             11532..12479
                     /locus_tag="TVW11_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1365112.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TVW11_001008"
     CDS             12495..13376
                     /locus_tag="TVW11_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1365113.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TVW11_001009"
     CDS             13520..14434
                     /locus_tag="TVW11_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1365114.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TVW11_001010"
     CDS             14606..16000
                     /locus_tag="TVW11_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1365115.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TVW11_001011"
     CDS             complement(16048..17739)
                     /locus_tag="TVW11_001011"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1365116.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TVW11_001012"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TVW11_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1365117.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TVW11_001013"
     CDS             18455..18805
                     /locus_tag="TVW11_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1365118.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TVW11_001014"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TVW11_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1365119.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TVW11_001015"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TVW11_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1365120.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TVW11_001016"
     CDS             23487..24710
                     /locus_tag="TVW11_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1365121.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TVW11_001017"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TVW11_001017"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1365122.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TVW11_001018"
     CDS             25318..25869
                     /locus_tag="TVW11_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1365123.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..27150)
                     /locus_tag="TVW11_001019"
     CDS             complement(26305..27150)
                     /locus_tag="TVW11_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365124.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27447..28019
                     /locus_tag="TVW11_001020"
     CDS             27447..28019
                     /locus_tag="TVW11_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1365125.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            28013..28303
                     /locus_tag="TVW11_001021"
     CDS             28013..28303
                     /locus_tag="TVW11_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365126.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
BASE COUNT         8375 a         4950 c         6334 g         9166 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacgcat aaaacacctc taaaatgtta ctaaatgcta
    27181 caaaaaaata aaatctacaa tagtatttta taatagcatt tagaaagagt aaaggaggaa
    27241 aatttatgag gagacatcta aaggttgtat tattacttgc agcactattg gcatttattg
    27301 taaatgaggg taattttcca tggtggcctt ggggaccata gtacttaact gattactgtt
    27361 atgttgttgc cattagacta tctagattaa tcaaagagta aaatacaagt agcttagtga
    27421 aagacatttt aagaggagaa aagcatatga agaaacgttt agcatttata ttagttgctt
    27481 ttggtatttt gggatttagt ttaggaaatg aagttttagc tgcagatact gcacctgcaa
    27541 gtgcaactat ggcaacagat agtgatgtga gtttttacaa tggagaactg ttgaaaaaat
    27601 atttggtcca aagtggtgat agattgtatt ttgattatga caaagctatt caagataaag
    27661 tttctgatgg tgtaatagat atgggattcc ttgttgagac aattagtgag gactattcac
    27721 aacaaacgtt tacctctcga aagtatttca aggcaggatg gcagctttat ggtaattatt
    27781 gtggacctgg ccataacgga aatcatttta ctttacctgt tattgatgtt ttagatcaag
    27841 gctgtcaaaa tcatgacagt tgttatcgat ggggagctgg gattggtgca aattgtgaat
    27901 gcaatcgtca gttagtaaat tacattaaag tatatcgacg gtggatgcca gctcatgcct
    27961 tgggggttgc tgatgctatt agagtatatt ttgaaacggt aggtgctatt ggatgttaac
    28021 cttaaaaaat attatcaatc gatactacat gtattatgta ttccttattg ttgtgatctg
    28081 gattgggatg ttttttgtac gatgggatac tactgtggct ggtgtattac tctatccact
    28141 gattatgaag caggtattta tcgtactagg agtagttgcg atgataatgg ccattatttc
    28201 tagaaaaatt gttcttggaa tttttggttt actatgctgt gctgcttttt ggattaatct
    28261 tttcttagct ttctatctat tacctggact tttgggaaat tagcgattaa actgtttttg
    28321 atgttttgaa gatgagaaac agattgtttt tctgtaaggc ttcctgttac ttctcaaatg
    28381 ctttggagta tctctttatc atttgttcac tgttgacaac gttaaaaaga ttattccaaa
    28441 catgggaatt gctgcttcag ggtattcctt gttaatattg gattgattag ttgttattta
    28501 tgcaaaatcc ttagagcatt gctttctcat tcttggttca tttgaataaa atgtaactaa
    28561 aaaaactttg taatcaattc aaattgtcac aagtataaaa gtaaaaaagc gactttgtta
    28621 gtgatctgat attcggaagt cctatcattg ctcgcttttt gttttttgag gttgattttt
    28681 attccgaaat tgttgtgaat aagtgcaatt ttaagctaag aattacctaa aatcttttga
    28741 agattactgc ttagcttcta atacctattt atcggtgtgt tgataattgg agagatagcg
    28801 ggattgtcat atgaaataaa tttta
//
LOCUS       DARYUW010000026        28086 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYUW010000026 DARYUW010000000
VERSION     DARYUW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28086
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..545)
                     /locus_tag="TVW11_001022"
     CDS             complement(<1..545)
                     /locus_tag="TVW11_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1365127.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRG"
     gene            887..1570
                     /locus_tag="TVW11_001023"
     CDS             887..1570
                     /locus_tag="TVW11_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1365128.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            1572..2309
                     /locus_tag="TVW11_001024"
     CDS             1572..2309
                     /locus_tag="TVW11_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1365129.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            2753..4447
                     /locus_tag="TVW11_001025"
     CDS             2753..4447
                     /locus_tag="TVW11_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1365130.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            4559..5413
                     /locus_tag="TVW11_001026"
     CDS             4559..5413
                     /locus_tag="TVW11_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1365131.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            5410..6264
                     /locus_tag="TVW11_001027"
     CDS             5410..6264
                     /locus_tag="TVW11_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1365132.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            6548..7888
                     /locus_tag="TVW11_001028"
     CDS             6548..7888
                     /locus_tag="TVW11_001028"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1365133.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            7866..8081
                     /locus_tag="TVW11_001029"
     CDS             7866..8081
                     /locus_tag="TVW11_001029"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1365134.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            8081..8950
                     /locus_tag="TVW11_001030"
     CDS             8081..8950
                     /locus_tag="TVW11_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1365135.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            8943..9770
                     /locus_tag="TVW11_001031"
     CDS             8943..9770
                     /locus_tag="TVW11_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1365136.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            9757..10227
                     /locus_tag="TVW11_001032"
     CDS             9757..10227
                     /locus_tag="TVW11_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1365137.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            10245..11906
                     /gene="recN"
                     /locus_tag="TVW11_001033"
     CDS             10245..11906
                     /gene="recN"
                     /locus_tag="TVW11_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1365138.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVVAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            12127..12999
                     /locus_tag="TVW11_001034"
     CDS             12127..12999
                     /locus_tag="TVW11_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1365139.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            13137..13988
                     /locus_tag="TVW11_001035"
     CDS             13137..13988
                     /locus_tag="TVW11_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1365140.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            13981..14823
                     /locus_tag="TVW11_001036"
     CDS             13981..14823
                     /locus_tag="TVW11_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1365141.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            14801..15388
                     /locus_tag="TVW11_001037"
     CDS             14801..15388
                     /locus_tag="TVW11_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1365142.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            15486..15761
                     /locus_tag="TVW11_001038"
     CDS             15486..15761
                     /locus_tag="TVW11_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1365143.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(15822..16526)
                     /locus_tag="TVW11_001039"
     CDS             complement(15822..16526)
                     /locus_tag="TVW11_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1365144.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(16837..18045)
                     /locus_tag="TVW11_001040"
     CDS             complement(16837..18045)
                     /locus_tag="TVW11_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1365145.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(18100..18993)
                     /locus_tag="TVW11_001041"
     CDS             complement(18100..18993)
                     /locus_tag="TVW11_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1365146.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            19362..19535
                     /locus_tag="TVW11_001042"
     CDS             19362..19535
                     /locus_tag="TVW11_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365147.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(19580..20515)
                     /locus_tag="TVW11_001043"
     CDS             complement(19580..20515)
                     /locus_tag="TVW11_001043"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1365148.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            20758..21453
                     /locus_tag="TVW11_001044"
     CDS             20758..21453
                     /locus_tag="TVW11_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1365149.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            21562..22083
                     /locus_tag="TVW11_001045"
     CDS             21562..22083
                     /locus_tag="TVW11_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1365150.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            22478..23017
                     /locus_tag="TVW11_001046"
     CDS             22478..23017
                     /locus_tag="TVW11_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365151.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            23156..23926
                     /locus_tag="TVW11_001047"
     CDS             23156..23926
                     /locus_tag="TVW11_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1365152.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            24038..26092
                     /locus_tag="TVW11_001048"
     CDS             24038..26092
                     /locus_tag="TVW11_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1365153.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            26104..26700
                     /gene="recR"
                     /locus_tag="TVW11_001049"
     CDS             26104..26700
                     /gene="recR"
                     /locus_tag="TVW11_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1365154.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            26848..27894
                     /locus_tag="TVW11_001050"
     CDS             26848..27894
                     /locus_tag="TVW11_001050"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1365155.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT         7735 a         5191 c         6931 g         8229 t
ORIGIN      
        1 tcaccgcgtt gtccttgctc gcctttttca ccgcgttgtc cttgctcacc tttttcaccg
       61 cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cgcctttttc gccgcgttgt
      121 ccttgctcac ctttttcgcc gcgttcgcct ctgtcaccct tagggccggc tggtccttgt
      181 tcacctttag gacctgtttc tccggtttcg cctttatctc cacgtggtcc cataggccca
      241 acaggacctt gctctccgcg ttcccctcta ggtccggcag gccccacagg tccctgagga
      301 ccaccttttt tagcttgtag ttctaagttt tgtaagtagg tttgcatgaa ttgtcttaat
      361 gtatgtaggt atactcttac ttcgccatct ccgagtccgt ccctaattag ttcagctgga
      421 tctggatagg actctaatcg cgtataatct tcagctcggg catttccagc tgttcctagg
      481 ctggccattg ttgctagggc aatggctgct gagcagacgc tgtacttgcg tattgttttt
      541 ttcatctttc tctcctttga tgatagtatc attacttttt caaaattctt tcccgaagaa
      601 gagtttaaca tggtagcttg ctatgagaaa cagctaggcg ccactttgtc tccgtagttt
      661 ttttaattca atgctgaatc gtctgatttt atcagagggt tattgttttt aaaggcgagg
      721 agttgctttg ctcagctagt ctagcaagtt cacaggtcag cttatgtttc ttatcaagct
      781 tgtttgtttt tgagaatatt tttcgataaa aagatgttgt attaatattc atgttatagt
      841 ataattatat tcgttgccat gactttatga atgttaggag ataggaatgg attttacctt
      901 tttacccaaa tactgggctt atttcaatta tggtgtgctt gtaaccatga tgatttcagc
      961 ctgtgttgtc ttttttggca cgattatagg tcttttagtg accctgataa aacgcagtca
     1021 tatcaagcct ttgtcttggc ttgtcagtct ttatgtctgg atttttcgtg gaacgccgat
     1081 ggtggtacag atcatgattg cttttgcttg gctgcatttc aacgatctgc ccattgtagg
     1141 ctttggtgtg ttggatttgg atttttcaag actgcttcct ggtattatta ttatttcctt
     1201 gaatagcggt gcttacatat ctgaaatcgt cagggctggg attgaggcgg tgccaaaggg
     1261 gcagctggag gctgcttact ctcttggtat ccgtcctaag aacgccatgc gctatgtgat
     1321 tttgcctcag gcctttaaga atattttgcc ggccttgggc aatgaattga tcaccattat
     1381 caaggatagt gccttgcttc agacgattgg tgtgatggag ctttggaatg gagctcagtc
     1441 ggttgtgacg gcgacctatc tgcctattac acccttgctg tttgcggcct tttattactt
     1501 gatgataaca acaatattgt cgcaattatt aggctgcttg gagcgcaagc tagcacaggg
     1561 agggagataa gatgactgag acagtgattt cgattcgtca gttgcataag agctttggca
     1621 agcatgaggt gctaaaagga atagacctga ccattaatca gggtgaggtt gtggtgatta
     1681 ttgggccatc tggctcagga aagtccacgc tattgcgcac gatgaatttg cttgaggtgc
     1741 caacaaaggg acacatcagc tttgagggcg tcgatattac ggataaggca aatgatattt
     1801 tcaagatgcg tgagaagatg ggcatggttt ttcagcagtt taatctgttt cccaatatga
     1861 cagtgctgga aaacatcacc ctgtcaccca tcaaaacaaa aggaatgtca agggctggcg
     1921 cggagcagag agcttatgag ctgcttgagc gagttgggct gagagataag gctgctgcct
     1981 atccggcaag cttatccggt ggtcagcagc agcgcattgc gattgcgcgc ggcttggcaa
     2041 tggatcccga tgtgctgctc tttgatgagc cgacctcagc gcttgaccct gagatggtgg
     2101 gtgaggtttt ggctgttatg caggatttgg caaaatcagg catgacgatg gttattgtaa
     2161 cgcatgaaat gggctttgcc aaagaggtgg cggatcgcgt gatttttatg gacggtggtc
     2221 ttgtgattga agagggcagt ccagttcagg tatttgaagc tcctaaggag gagcggacca
     2281 aggacttttt gagcaaggta ttgtcatagc tggcgcagct aaagggcagc atgtcacctc
     2341 aaggtctggc tattagtcaa ttggctgttt gttttgggca ttttgtttgt aaaaggctta
     2401 gaaagtctgg ttggtgctgt agccatatct ggctttgcta cgcttgggct gctagctggt
     2461 cagtgggtat catagtgatt ggaggtgtgg tctctttatt ggtcaacatt gctgtggcag
     2521 gctagcacag gggctttgct tgttgtgctg ggtaaggggt ttcatttgca tgactgttaa
     2581 cattgcttaa ttgatgaatt aggttgactt ttgttttatt gtttgatact attcaggtaa
     2641 gtctgtcatt agaaagcgct ttgctttttt gatgatggaa atcatgatca tatgatcacg
     2701 tcttaggtaa tatgttgttg tcaacatggt ggtctgaaag taggaggata atatggacta
     2761 caaagctgtt tatcaggagt ggctgcacaa tgattttttc aatgaagaaa tcaaggcaga
     2821 tttagaggcg attaagcatg atgaggctga gattcaagac cgtttttata aggtgcttga
     2881 gtttgggaca gcaggactta gaggaaagct cggtgctggg accaaccgta tgaatattta
     2941 catggttggt aaggctgcgc aggctttagc taataccatt attgatcatg ggccagaggc
     3001 agtctcacgc gggattgcca tcagctatga tgtgcgctat aagtctaagg aattcgcaga
     3061 attgacctgc tcgatcatgg cagccaatgg gatcaagtct tatatctaca aggggattcg
     3121 tccgacaccg atgtgctctt atgcgattcg tgccttgaac tgtatctctg gtgtcatgat
     3181 tactgctagt cacaatcctc aggcctacaa tggctacaag gcttattggg aagaggggtc
     3241 acagatccta gatgacattg ctaatcagat agcggttcat atggacgcta ttgagcgctt
     3301 tgaggacgtt aagcagatac cctttgagga ggcattggca agtggtctga ccagctatat
     3361 tgatgatagt atagaggagg cctataagaa agaggtttta ggcttgacca tcaatgatac
     3421 tgatattgat aagtcagtgc gtgtggttta tacacctttg aatggcgttg gtaatttgcc
     3481 tgttcgtgag gtattgaaga gacgaggctt tgatcatgtc tttgtagtgc cggagcagga
     3541 aatgccagac ccagatttca caacagttgg ttatccaaat ccagaggtac caaaggcctt
     3601 tgcttattca gaaagactag ggcaagaagt aggagcagct attctgattg cgactgatcc
     3661 ggactgtgat cgtgtggcac tagaggttcg agctgctgac ggtagttatg tctttcttaa
     3721 tggtaataag attggtgctt tgttgtccta ctatatcttt tcacagcgtc atgctaggca
     3781 taatcttcct gacaatcctg tccttgtcaa atcaattgta acaggggatt tatcaaaagc
     3841 tattgccgct aaatatgacg ttgaaacggt tgagactctt acaggcttta aaaacatctg
     3901 tggtaaggct aatgactatg acatcacaaa ggagaagacc tacgtctttg gctatgagga
     3961 aagcattggt ttttgttacg gtacctttgt gcgtgataag gacgcggtta gcgcctcaat
     4021 gatggtggta gaaatggctg cctactacaa gcaaaggggt cagtcactct tagatgtgct
     4081 tcaagacatt tacaaggaat ttggctatta caatgagcgt caggtagcgc tagagctaga
     4141 gggtgttgag gggcagaagc gtattgcacg tatcatggag gactttagaa atgagcctat
     4201 tgagcatgca ggtgctatga gcttgaagac cattgtagac tttaaggacg gctaccttga
     4261 ttttccaaag caaaattgtt tgaaatatta ttttgatgat gggtcatggt atgcgctgag
     4321 accatctgga acagagccta agatcaagct ttacatctat actattggtg aaacagaggc
     4381 agacagcatt gctaagctag acgctattga gtcagcttgt caagcaaaga tggacagtgt
     4441 cagctaattg ttcaagctct gcaacagaaa atcagctaat caataagcaa aaaggaaaag
     4501 gaagtgacag tgcttccttt tttcgttata atagttaaaa aattagcaag gagtgcatat
     4561 ggtacagatt attgatggga aggccctagc acagaaaatg caggcagcat tggctaagaa
     4621 ggtagagagc ttaaaggcag aaaaaggaat tgttccaggc cttgttgtca ttctggtagg
     4681 agacaaccct gctagtcagg tttacgtccg taataaggaa cgcgctgcct tagcagcagg
     4741 ctttaaaagt gaaaccgttc gcttgtctga ttcagtctgt caggaagagt tgatagagct
     4801 cattgagcaa tataatcaag atgatacgat tcatggtatt ttagtgcagc ttcctcttcc
     4861 gcaccatatt aatgacaaaa gcattatcct tgctattgat cctaaaaagg acgtcgatgg
     4921 ctttcaccct atgaatacag gtcatctgtg gtcaggtcgt ccgaatatgg tcccttgtac
     4981 tccggcaggg attatggaga tgtttcatga ctatggtatc gaacttgaag ggaaaaatgc
     5041 tgttattgtc gggcgctcaa atattgttgg gaagcctatg gcgcagctac tgttggataa
     5101 aaatgctacg gtaacgctta cccattcgcg cacgcgccga ctggcagata tttgtcgtcg
     5161 tgctgatatc ttgattgttg ctattggtca ggggcatttt atcacaaagg agtttgttaa
     5221 agagggtgct gttgttatag atgttggtat gaatcgtgac gtcaatgggc gattgattgg
     5281 agacgtcgcc tttgatgagg tgtcagagct ggctagcatg attactcctg ttccgggtgg
     5341 tgttggaccg atgaccatta ctatgctttt ggagcaaacc tatcaagcag ctctaagaag
     5401 ggtgagtcaa tgattataga tcaatcgttt gttgctaggg ttgttgttcc gcggcaggct
     5461 gactcccata aggggagtta cggcagagta ctgttagtag gtggcttgta tccatacggt
     5521 ggtgctatta ttatggtagc gctggcctgt gttcatagtg gtgctggcct agtaactgtt
     5581 gcaactgata gagaaactat tgctgccttg catagtcatt tgccagaggc gatggctatt
     5641 gcggtagatg atgaggaatt actgttatct cagctaggta tggcagacct gattttgatt
     5701 ggtccggggc tgtcggagaa tagcagagca gctaggctgt ttgaattggt ccttgcacat
     5761 gtcgctgatc atcaggtatt ggtcattgat ggctctgcct taaggctttt agcgaaaagg
     5821 gcagctgatg ttaagcagct gaggtgccct cttgtgttaa cgccacacca aaaggaatgg
     5881 gaggcgctgt caggtttagc gattgatcag cagtatgatg ctgccaacca agcagctctc
     5941 aagcattttc caagggctac gattttggtt gctaaaagct cagcaaccaa gatttatcat
     6001 ggcaaccaga tctaccggct aagagtgggc ggaccttatc aggctacagg tggtatgggg
     6061 gataccttgg caggtatgat agcagggata gctgtccagt ttccagagtc aagcttggtg
     6121 gctaaggttg cttgtgcgac ctatctgcac tctgcgattg ctgatgagct ggcaaagact
     6181 gcctatgtgg ttttgccgac tgctattagc tatgagcttc ctagatggct aaaggcaatc
     6241 agcacaggcc agaagctagg ttgaggctgt gctgcgaggt cgtttgggaa aagcggttaa
     6301 ttggtaggca tgacagcagc tggtttcagt cgtttagcta ttttgagttt agagctgcta
     6361 gcttaagact gggtgctgct ttatgattca aggaagctat cattggaaaa acttgtgtca
     6421 agctgtagaa gccctagctg gcttcttttt ttgtctcttt tttgctcact atttatgtgg
     6481 aaacatgata taattgcatt agtatacagt tggagcagtt aggcttcatg aagtgaaagg
     6541 taaactgatg gcagactatt tatccgtcac tcagctgaca aaatatttaa aattgaaatt
     6601 tgatcgagac ccttatctgg agcgtgtcta tctcactggt caggtatcta atttcagaaa
     6661 aagaccaaat caccaatatt tttccttaaa ggacgaggga gcggtgattc aggccaccat
     6721 gtgggcagga gcttataaaa agcttggctt tgatttagaa gagggcatga agctcaatgt
     6781 ggttgggcgt attcagctct atgagccaaa tggctcgtat tcaatgatca ttgaaaaggc
     6841 tgagccagac ggtattggtg ctttggcgct gcaatttgag cagctcaggc aaaagctggc
     6901 tggtgaaggc ttctttgatg agaggcataa gcaggccctg ccgcaatttg tgacaaaggt
     6961 aggtattgtg acgagtccaa gtggggctgt gattcgtgat attatcacaa ccatctcaag
     7021 gcgttttcct ggggtgagta ttcttttgtt tccaacaaag gttcagggtg agggggcagc
     7081 tcaagaggtt gctgctaata ttactaaggc taaccagcgt gaggatctgg atttgttgat
     7141 tgttggacgc ggcggtggct cgattgagga cctgtgggct ttcaatgagg aaatcgttgt
     7201 tcaggctatt tttgagtctc gcctgcctgt tatttccagc gtaggacatg agacagatac
     7261 aaccttggct gattttgtgg ctgatcgcag agctgccacc ccaaccgcag ctgcagagct
     7321 ggcgacacct attacaaaaa cagatattgt ctcttggatt gctgagcagc agagccggtc
     7381 ctatcaagcc tgtctgcgct atatcagaca agggcaggag cgggtggata agctttctta
     7441 ttctgttatt ttcaggcagc cagagaggct ctatgatgct tatagtcaac gcttagatag
     7501 gcttacgacc tccttgatga ccacttttaa agagacatta tcaggagcta agcaggagca
     7561 cttgattttg gagcatcgtt tagcctctgt caatgtacag gcaaggcttg agcgttatca
     7621 ggatcgtctg gcaactgcgc atcgtctctt gatagccaat atgaccaatc aatatgacag
     7681 taagctagca ggctttgagc gagctcaagc tgccttgctg tcgcttgata cgagccgtat
     7741 cattgcccgc ggctatgccc tgttaaaaaa ggacggtgta gtagctgctt gtgttaagga
     7801 cattaaaaag ggagatcatc ttagtattat catgcgtgat ggtcaattag aagtagaggt
     7861 agaagatgtc aacgaaaaaa atatttgaag agcgtttaca agaattagag gccattgtga
     7921 cgaggctaga aaatggtgat gtgccactag aagaggccat ctctgaattt caaaagggta
     7981 tggtgctgtc caaggacctt caaaaaacct tacaagcagc tgaaaagaca cttgttaagg
     8041 tcatgcaggc agatggcaca gagctagaaa tggatgccta atggataagc taacaagaat
     8101 taatgccacg attcatcagt attatgacag gcagtctact gtttcagcag atctggagga
     8161 ggccatttta tattctgttg atggtggagg aaagaggctc cgtccactca tgttattgga
     8221 gctgctagag ggctttggtc ttgccttgac agacgctcat tacgcggttg ctgctgctgt
     8281 tgagatgatt catacaggaa gtttgattca cgatgatttg cctgctatgg ataacgatga
     8341 ttaccgtcgc gggcgactaa ctagccacaa gcaatttaat gaagcaactg ctattttggc
     8401 aggagatagt ctttttttgg acccttttgc tctaatcgca ggggcagatt tgccggctga
     8461 cctgctggtg caattgattc agcagttttc cttagcgtca ggaacctttg gcatggtcgg
     8521 tggtcagctc ttggacatga agggtgagca tcagctgctg gatattcagg agctatctga
     8581 tattcatgcc aataaaacag ggaaattgtt gacccttcct tttgtggctg cgggtatcat
     8641 agctgagcag tcagcagacg ttttgtcttg tctgtgggag gctggtaggc ttgttggaca
     8701 ggcctttcag ataagagatg atatattaga ccttacggct agctttgctg atcttggcaa
     8761 gacaccgcaa aaggaccttg ctgctgcaaa atcaacctat ccgagtctgc ttggtttaga
     8821 gcgctcaagg gctattttgg aggagtcttt gagtcaagcg ctagctattt ttagcagact
     8881 agaaagggaa gaaggctttg agtctcaggc tattatcaaa aggatcgagg ggttgcgact
     8941 aaatggctaa agaaagagta gatgtgctag cctatagaca gggacttttt gaaacgcgag
     9001 aacaggccaa gcgcggtgtg atggctgggc tagttatatc agctataagt ggcttacgct
     9061 ttgataagcc tggtgaaaag attgatgagg ggatcgaact aaggctcaag ggtgagaagc
     9121 ttaagtatgt cagccgaggg ggtctcaagc tggaaaaagc cttgcaggtc tttgggatct
     9181 ctgtgcagga taaggtgaca attgatattg gtgcttcaac aggtggcttt acagatgtta
     9241 tgctacaggc aggagctagg ctggtttacg ctgttgatgt tggaaccaat caattggtct
     9301 ggaagctcag gcaggatagt cgtgttcgaa gcatggagca gtacaatttt cgctatgcaa
     9361 agctagcaga tttttcagaa ggtcagccag cctttgccag cattgatgtg tcctttattt
     9421 ctcttagcct gatactgccg acattgcact gtattttgca ggaaggggca gaggctgttg
     9481 ctctgatcaa gccacagttt gaagcagggc gcgagcagat tggcaaaaaa gggattgtca
     9541 aggatagact gattcatgaa aaagtgatta agcaggtggc agatactgct cttaattgcg
     9601 gatttatcgt taaggggctt gatttttcgc ctatccaagg tggtcatggc aatattgaat
     9661 ttttggctca tttagtcaag ggaaagggct ccaaggctat tgatgatcag ctcatacaga
     9721 gcgttgttag cagtgcacat aaggaattta aacagcatga aaaagagtga acgattagat
     9781 ttaataaaaa aaatggtttt gtctcatgag attgagactc agcatgagct attaaagctc
     9841 ctagctgatt atgggctaga gctaactcag gccactattt caagagacat gaatgaaatt
     9901 ggcattgtca aaattccatc tggaactggg cgttatgtct atggcttgtc acaggatagt
     9961 ggcaagcggg tggtgcaaag gcctgcctct atcaaaaaaa cgattttgga aatgtctgaa
    10021 aaaacagcgg gcttggagca gcatattcac ctcaacgttg ttccaggcaa tagcaagcta
    10081 atcaaacgtt atttgatgac agacttttca ggtcaattgt ttagcctgat tgcagatgat
    10141 gatagtttgc tgttgattgc aaaatcagaa gcagacgctg atcatatccg tcaggaattg
    10201 tccctttgga tgcagggatt ggtctaaaaa atagagagaa gccgatgtta ttagaaattt
    10261 ccattaagaa ttttgctatc atagaggaaa tctctttaaa ctttgaaaac ggtatgaccg
    10321 tactgactgg ggagacaggg gcaggaaagt ccattatcat tgatgcgatg aacatgctgc
    10381 tgggtgcgcg cgcaagcact gaggtgattc gacatggtgc tgataaggca gagattgagg
    10441 gcttcttttc ggttgatgct aatcctcatt tagccgctgt gctggcagaa tcagggatta
    10501 gcatggaaga ggagttgatt cttcgtcgtg atatttttgc taacggtcgt agcgtcagcc
    10561 gtatcaatgg tcaaatggtc actgtcagca ccctaaaaaa acttgggcag tttttagtgg
    10621 atattcatgg tcagcatgat caggaggaat tgatgcgtcc acagctgcac cagcatattt
    10681 tggatagttt tggagatgag gcctttgacc agctcaagca gtcctatcag cagatttttg
    10741 atcgctataa ggctttgcga aggcaggctc ttgagaagca aaaaaatgaa aaagaacatc
    10801 aggcgcgcct tgacctgctg gcctttcaga taggggaaat tgaggcagca gatttggtta
    10861 gaggagaaga tgacctgctt aaccaagaaa ggcagcgatt gctcaatcac aaaaagattg
    10921 ctgatacctt aaccagtgcc tacctttcct tggataatga ggacttttcc agtctctcac
    10981 aggtccgctc tagcatgaat gagttgctgt ctattgagga ccttgcccca gagtatcagc
    11041 ttatatcagc tggtgtgtca gaggcttatt atattcttga ggaggtcaca aagcaattat
    11101 ctgataccat cgaccagctt gattttgatg caggcagatt gcaggacatt gagctgcgtt
    11161 tagacagcat taatagtctg acaagaaaat atggcggtgg tgtgaatgat gttttggact
    11221 actatgccaa tattaccaag gaataccagt tattaagcgg agatgaccgt tcctctgatg
    11281 agctagaaag ggaattaaag gtccttgaga agcaactggt gatgactgcc tcacagctaa
    11341 gtgacaagcg tcatgccctg gctctagagc tagaagccga catcaaagct gagctgagag
    11401 agctttatat ggaaaaggcg gactttaagg tccactttac aaggtcaaag tttaatcgag
    11461 aaggcaatga aagcttagaa ttttatatct caaccaatcc aggtgagggc tttaagccgc
    11521 tggttaaggt tgcttcaggt ggtgagcttt cccgcttgat gcttgctatc aaggctgcca
    11581 tttctaaaaa agaggacaag acgagtattg tctttgacga ggtggatact ggagtttcag
    11641 gacgtgtggc ccaggccatt gctaaaaaaa tatataaaat tggcagctat ggtcaggtat
    11701 tagcgatttc gcatttgcca caggtggttg ctattgcaga taaccagtat tttatttcca
    11761 aggaaagcaa ggaggagtcg acagtgtcta aggctaagct gttgacacag gaggagcgga
    11821 tcgaggagat tgcgaagatg attgcaggag ctgatgtcac agagacagca agaaatcaag
    11881 cgcgtgaatt gctaggtaag gactgagtat catagcaaaa gcagaacagt agctttagag
    11941 caagcttgcc tgctgcactt gtcgctacat gttcagaatg agccacctga aaggcaagca
    12001 agaaggctag ctcttatgcg tatgctatca gaagctaagt ctttttgtct cttgcattgg
    12061 cgagtgattg attgataata ttatgataaa tagaaggact aaaagaatac tgactgagga
    12121 ggtaaaatgc tgaaaaaaag aatgggcttg gctagtctgc tagtgttgat gacctttgtg
    12181 tatcagtgct gttcagttac tgctgagcag tattccgata ctgaggttga ggtgctgcag
    12241 attagcgagg agaaaagcca gatcatggaa aatcaagagg cgcttaaaga cctcaccacg
    12301 tcgtctgatc agctaaagaa ggaagcttta aagcctaaag aggcagctac caacaagagc
    12361 aagcaagagg cttcgacagt ttatttagct gaggacgatc ctgtaaccat tgatagctct
    12421 gacgaggaaa gcaatcaaga tatcatagcg gattctgttc ctgatttggt tattaaaggt
    12481 gatcaggtgg atgtatctga ggttatggtc tctgtaaagg aggattcatc gaaagttgct
    12541 aagcaaagaa ctgacgcagc gcagcggtac agtatagcca agcatcaatt gacccaaaag
    12601 cttgaggcct ttaatgcggc aacggaccaa ttgctgacca tgattgctaa aaaatctgat
    12661 ttgactggtc agtattatgt ggttgggcat tcgttgggag aaatgctggc tgctcaaaat
    12721 gagaaaaagc ttgctgagca attagtcatg caacaaaagc acaaaaaagg cttaggctca
    12781 tcagtcacta ttttagacga attaggacgt gtgatttctg acattagtgg tcataaaggc
    12841 atgcttcctt ttaatcgtaa gatcagcttt aaggtacatc aagtcagata cgatcttcca
    12901 ctaactggtg atcgaacagt gctacctgcc cagctggctg gcttactgct tttactaata
    12961 ggtcttatgc tgcctaaagt agctaacaag aaaagctaag atatggtctt ggctttttta
    13021 tcttttaaga gggtgagttt ttgacagatg ttttagctaa caccaagagc tagataccag
    13081 ctttgcttta tttttaaagg agtgataaaa taaagagacg ataaatgagg ttagaaatgg
    13141 aacttaagat gggaactatt aaaattgttg cagattcatc aatgacgatt gaaccagagc
    13201 taatcaaatc tcttgatatt acggttgtac cgctttctgt catgattgat agcaagctgt
    13261 attctgataa tgagctaaaa gaggaagggc aatttctaca gctgatgaga gctagtaagt
    13321 cattgccaaa aactagtcag ccaccggtag ggctttttgc agatatttat gagcgattgg
    13381 tcaaggaggg ggcgacagct attgttgcca ttcacctctc accagctctt tcaggaacaa
    13441 ttgaggcatc acgtcaggga gctgaaattg cagcagcacc agttacggta ttggactcag
    13501 gctttacaga tcaggctttg aagtttcagg tggttgaagc ggctagactg gctcaagctg
    13561 gcgctagcct tgaggaaatc cttgaggcgg tagaggatat taaacgaaag acagagcttt
    13621 atataggggt atcagcactt gagcacttgg ttaagggggg acgaatcggt cgtgtgacag
    13681 gcttgcttag ctccttgctg aatattcgtg tggtcatgga aatgaaaaat gataccctgc
    13741 aaacacttgt taaaggacgc ggcaataaga cctttactaa atggctggat agctatctag
    13801 cagaaaatag ccagcgacag atagctgagg tggccatttc ctatgctggt cagagggatt
    13861 ttgctgatag cctgaagaag acaatcgcta cggtctttga tgggccaatt actgttttgg
    13921 agactggctc aatcattcaa acacatactg gcgagggcgc ttttgcggtg atggttagat
    13981 atgaataagc gagggttttt gggaggcctt atcttctttt tcagtgtttt tgccttatca
    14041 tttgtgatat tagctgtcct tattccaaag tctgacccac agctgaagaa aagtgatttt
    14101 ctaaaaaata agaagataag cctcaattat attgctattg gagactcctt gacagaggga
    14161 gtgggtgatc tcaccaacca aggaggcttt gtgcccttat tgtctggtga tcttggagac
    14221 tactttaatg ctaccgttaa tactgaaaat tacggtgttt ccggtaatac cagccagcaa
    14281 attttaacga gaatgactga gaacaaggag atcacagagc agctcaaaaa agctaatctc
    14341 atgacattaa cggttggtgg caatgatgtc ttggctgtta ttcgcaagaa cttagctaat
    14401 cttaaggtat caagctttaa aaagccagca aggcaatacc aagagcgctt acgcaaaatc
    14461 cttgatttgg ccagaaagga taatcaggat ctgccgatct ttgttttagg tatctacaat
    14521 cctttttatt tgaattttca ggagctaaca gaaatgcaga cggtcattaa tgactggaac
    14581 aaaaaaacac aagaggttgt tgatgactat gaccatgttt actttgttcc aattaatgat
    14641 ctattgtaca aaggagtaga tggtaaagag ggcattgtcc agtcaacagg agagcaaaca
    14701 acgattgtga atgatgcttt gttttcaggg gatcattttc accccaataa cacaggctac
    14761 caaatcatgt cagacgcagt aatggagaca ataagaaaga atggaaaaga aattaaacct
    14821 taattggtgg aaatgggctt ttttgctatt attggctttt aatgcagcct ttttagcagt
    14881 tattggaagt cgtattatac aaataagaga gcctaagtct gagctgatca atcaaaaagc
    14941 agcaaagaat attaaaatag ggaccttaac aaccactaaa gagcaattaa atgaggcagt
    15001 cgttagctac ctaaaggatt ttcagacgga aaaaatgacc tataaggtgt atgccacctc
    15061 ctcgaccatt ctctttgaag gaacctatca gctcttagga tatgaggtgc cgttatacat
    15121 ttattttcag cctcatcgct taaccaatgg tgcgatacag ctgcaggttc tctccttttc
    15181 tgtggggacc ctttctttgc cggaaaagga cgttttgcaa tacttgaaat ccagctataa
    15241 gctgccaaaa ttcgttgaag tcttacctaa gcaatcggct attattatca atctacagca
    15301 attggaaaat gatgccaaca tctatttaaa ggctcaaaag attgatcttg tcaaggatga
    15361 tattcgattt gacatctata agaaatgagt ctaactaacg tttaatactt gacctgtggc
    15421 tgttttttag atatgataat atctgttaaa gcgttaagct tactaattat ttggaggatt
    15481 gttaaatggc taacaaacaa gatttaatcg caaaggttgc agaagcaact gagcttacaa
    15541 agaaagattc agcagcagca gttgacgctg tcttttctgc aatcgaagct tttcttgctg
    15601 aaggtgaaaa ggtacaatta attggttttg gtaactttga ggttcgtgaa cgcgctgctc
    15661 gtaaaggtcg caacccacaa actggtgaag aaattgaaat tgcagcttca aaggttccag
    15721 cattcaaggc tggtaaagct cttaaggacg ctgtaaaata ataaatcaaa aaaagcccta
    15781 tctcattaag ctgtttagcc tgtgagatag ggctttttcc attaaggaag gagtcttgtt
    15841 tcaataagta atcttgtgtg atcgtctgaa agattagcgc caataatttc taatgtgcac
    15901 tgtcttggga acaagagttc catttcataa ggataaaatg agtagggctg tacaaaagca
    15961 gcctggctgc cttgagggac ctgaattctt aattccactg agcgatgtgg catagcagca
    16021 tttttgatgg ctgtagtact cataaagcct tgctttgtat aatgagtgcc tggcttgatc
    16081 gctgatagga tctgcggatc aaaggtctta tcatggtagt aacgagcgag ttcctcttca
    16141 gaagtgccca attctgttaa gaatgtttca taaacatagc gatagacgat gatattccaa
    16201 gggatggtta gcttatgagt agcactatca agtaaggcta cagactgctg cagctgggca
    16261 tccaactggc tggtatctcc catcacctgt tctagggcta ggttaatagg gctggcagag
    16321 gcgtatgtat actgatacat catctttttt tctgcttctg taaaggctgt ttgagacctc
    16381 cagcgattgg tgataatgta tttggtaaca tcaggctcac taaatttata ataaggctta
    16441 aagctattcc catagggctc aaaaacaact gtttgtcctt catcataaga ctgtgccttg
    16501 atggttgaag gctgaacgac aagcaacgat aagaaaaatg taaacaagca tagtgtacga
    16561 atagctatcc tttgataaga taactttgcg ttatgatgtt gatgagtcat ttagcttttc
    16621 ctcctttaca gtagtgccaa gagtgtcatc acctaatgat gatgtctgtt gctaacagga
    16681 ttagccttag ttgaaatgat tacaaacttc cttaatgtaa caaacataat aaaaataaat
    16741 tattttttta ttatatatta gttaagctca gatgacaagc tatttgattt ttttctgaga
    16801 taatgttaca agggatttct aacaccaatg actaactcag atgaagggct ttttcttgga
    16861 ggattgccta tagttacaat agtaggcaag actggcagtc gccatgatac ctattccaat
    16921 aacagcaaag gttgctagat gaacagaggc tggtatacag gtcatgatgg tagttgccag
    16981 tggcattaag agaatagcag ttgtgacgat tgagctaaag actcgtccta gcaatgcctc
    17041 aggaactttt ttttgaacga tagaaaagaa gtgaatgtta aagattgtta aaaagcattc
    17101 aaaccataaa ttcccaaggg caatcacaat gactggaagc ttcaagagag ccatagctgt
    17161 tattagaagc atccctaggc cactaaggcc tagggatagg agtaagcttt gctgattatt
    17221 tttaaagagc ttgttagcca taaaagctcc taagatagcc cctaaagctc ccatcgaaag
    17281 aagactagca tagcttgatt ggctgcctag cagctgattc gaaaaaggaa ttaaataatt
    17341 gaaagcagca ataaagaaat tcacaagaga agcaataatc aacaaagaaa aaatgtcatt
    17401 gtcatggtag atgaattgca gcccctcctt aatatctgtt aaaagctgaa gcctattgcc
    17461 ttggctgctc tgtttagtga tgtgcctttc tttgtccttg attgtatata gacatagaaa
    17521 ggacaataga aagctaatgc tatctagagc caaggctgtt ttgatgccaa agcaatccat
    17581 cactaaaaaa gcaagcattg gtgaggaaat actgatgatt tgagatacga tttctagctg
    17641 agcattgaaa tgaacaagtc tttctgtttc aactagtgtg accacatagg ctcgaaaagc
    17701 agttccagag aaggcatacg atattgctaa aagagcatta acagtgataa gcccataaag
    17761 catgatagta gggttagcta tcagggctaa aagtccgcag ctgatagctc cgatagcatc
    17821 tgtccacaat aacaattgtc gtcgtttata acgatcagca atggcgccac cgataggatt
    17881 taagatgagt gaaataaggc cttcagctag ctgataataa cccaaatatt gtcggccagt
    17941 tgctccgagt ccagcaatcc cgctgctgtt gctgtagtcg taaacagtat tgcctatttt
    18001 gttaatagct cgacttgcga gcagctggta gtcgtttttg cgcatgataa aacctccaaa
    18061 agattatgtg gttttattat aaatcagttt tttagggtct tatgtttttt tgcaaataag
    18121 gctagaggag gctacaaatc tttcaaaatc cttttggtaa ttgtgcgcta ggtgaggaca
    18181 atccaggctc tcaaaaatgg aaatagcagt agtcatatcc ttaatgccag acaaacactg
    18241 tcctctttgg tagtcctcta agccctttaa aaataaaaag atggtttttt catatagctt
    18301 ggtttcatta ttgagtaggg ctagtatctg cttttgataa tagcgcgcat agtcaagctg
    18361 atgtcggtgg atacaggttt cccaaatatt gagaagggtg atggtaacca aatgcttatt
    18421 ggttgaaatg ctttcgtagt aggtatgatt gtttagaatt tcctttccca ttttatctaa
    18481 taagggaata tcaataaaaa gatagagatt tccaattaaa atcagctcat agatatgcca
    18541 gctttcagtc ctaaaaaggt agtcagtgac ctcatcaaga taagccttag gaaaaggaat
    18601 gctaggattg catttacaga taaagccttg gagtagaatg ctgtttaaat agtaacgatt
    18661 ggtatcagga tcagcttggt gctttgccaa ttcctgcttt tgcagctgct tgaatccctc
    18721 aatatcgcgt gcatattcca gcttgatcag ctgcgacatg aattgaattt gctctgtctg
    18781 tttgaagttg gcagctatgt ccataaattc gctgatttcc acttgcatgc tgtctaaagc
    18841 tgttaaaaac tttgttactg atagatcaga ttcgccgcgt tcaaagcggg ataactgaga
    18901 caaggacacg tctttactgg caagctgctg taaggtgata tttctgtttt gtctaatgct
    18961 gcgaaatgct tttcccaact gatgattagt catatttttt cctcctctaa tgagtatatc
    19021 atgtaaggct tctgttgctg tattttcccg tatgtgcaaa ccttgaaact tgtctgctgc
    19081 cgccacaaag gcatgaaaac atttacactt tttgatagct atttttatca ttgatgtagt
    19141 ctttttcgca acatttgtac gggatcatca gattaaaatt aagaaactga tgatgtgaca
    19201 ctgtaaacat gctaaaaata tgttgaacaa tgcctgtagc tggaaaatgg gtacatgtat
    19261 tttcttcatg cctgcgtcgt gacctgctgc tattaaagct tgcttgaaag ggaaaaagag
    19321 cttataatag cagtgagaac attaaaaatg aaagtagaga tatgccaata attgttatcc
    19381 ttggacttgc tatcttttcg gtggttaagg tcattatttt tctatgcttt tataaagcat
    19441 ttgagaaaaa acaactaaag aagctagaac aggatcaaaa agaaaccaag caggcgattg
    19501 accaagagga gtcaaaaaaa gcctttccct tttaacataa agctagaaaa agtctgagac
    19561 ctttcgtctc agactttttt taaggcttat attgtaattg accacgaaaa tcgtctagtg
    19621 tctggtagcc cttttcagcc ataatgtctt gtagctcctt agtgatacgc ttaaaaatag
    19681 ctggaccttc ctggtgcagt gctgttccaa tttgtaccat agctgcgccg cataggatat
    19741 gctcaaaggc atcacgtcct gttttgacac cgcctgtgcc aatgatctga atagaagagt
    19801 taagccgttg gtaaaaggca tgaacattag ccagggcagt tggcttgatg taatcaccac
    19861 caataccacc aaagccgttt ttaggcttga tgacgacctg ctcatcatca ataaccaagc
    19921 cattgccaat ggaattaaca cagttggcaa aggctaaggg gtattgattg aaaatggctg
    19981 cggcttggtc aaaatggaca atatcaaaat aaggaggtag cttgatgcct agaggcttgg
    20041 tgtaatagga aaagatcttt tttaggagct gatctgtggc ttcaaagtca taggccagct
    20101 gaggcttacc tgggacatta gggcacgaca ggtttagctc gacaagtcct tgataatcag
    20161 aggcctgaat agcttttagg atagtctcgg tttcttcagc agacatgccc acaacagata
    20221 aaaagtggtg cttgcttgct tgatcctttt gcatttctgt gacaatatct aaataatact
    20281 ggtagccatg attaggaagt cccattgaat tgattgagcc aagtgctgta tctgcatagc
    20341 gaggctcagg gttgccctgt cgaggggcta gagtacctgt ttttgtcaca aaggacccag
    20401 cctcagaggc ctcaatggct agcagctctt ccttggtcat gcaatacact ccagcagcgt
    20461 tcatcaggca attattaaag gcaaatgtag cgatttttgt ggcagtagaa accatgtttt
    20521 cctccatttt tagacaaatt ttttctattc tatcactagg gcatgagaat agcaaggcat
    20581 ttttgcaaaa tacttgcttg aaggctttct tttgtgaggt tttagcgttt ttcatgatat
    20641 taacaaaatg attttcaata aagagaggaa tagactagct tttttgacct attttttgta
    20701 aaataggagt tgtaaaaagg caagaagcct ttaaacttaa taaggagata ttaactaatg
    20761 gtaaaattgg ttttcgctcg tcatggtgag tcagaatgga acaaagcaaa ccttttcact
    20821 ggttgggctg acgttgattt gtccgaaaag ggaacacagc aggctattga tgctggaaaa
    20881 ttgatcaagg aagctggtat tgcatttgat cttgccttta catctgtgct taagcgtgct
    20941 atcaagacaa ctaatcttgc acttgagtat tctgatcagc tttgggtacc tgttgaaaaa
    21001 tcatggcgct tgaacgagcg tcactatggt ggcttgactg gtaaaaacaa ggcagaagca
    21061 gctgagcaat ttggtgatga gcaggttcat atctggcgcc gttcatacga tgtgttgcct
    21121 cctgatatgg ctaaagatga tgagcattca gcacatactg atcgtcgtta cgctcatctt
    21181 gatcattctg ttattccaga tgcagaaaac ctgaaggtaa cactagagcg tgcccttcct
    21241 ttctgggaag ataagattgc accagcctta gttgatggta aaaatgtttt tgttggagca
    21301 catggtaact ctattcgtgc ccttgtcaaa cacatcaagc aattatcaga tgacgagatt
    21361 atgaatgtgg aaatcccgaa cttcccaccg cttgtgtttg aatttgatga caagctaaat
    21421 cttactgctg agtactacct cggtggtgaa taatgctgtg aggccagacc tagctctggc
    21481 tttttttgtt atgtgataaa aaaggcgttt ccaacagaaa tgtgatatga tagttaaaaa
    21541 gtggtaaaag aagggaatct tatgaaagta aaggaacgcc gagaagctat tacagatagg
    21601 ttaagccaag cacaagaagc catctcagca actagcttag ccaaggcatt gggagttagt
    21661 cgtcaggtga ttgtcggaga cattgcctta cttagggcgc agcagcttga cattatttca
    21721 acaccaaagg gatatatcct gtcaaatgct ttgtttagtc atcactattc tgctagaatt
    21781 gtttgccagc atggacctga gcagacaagg caggagttgg agttgatatt agcacatgat
    21841 ggcattgtga ccaatgtgga ggtagagcac cctatttatg gcatgctgac agcaccgctt
    21901 aacattaaaa gctcagctga tatcaataac tttattgaaa agctcggagc ctctaaggca
    21961 gaattattgt cgtctttgac agagggtctg cacactcacc ttttgtcctg ccctgatcag
    22021 gaggcatttg aagagatcaa gagagatcta gcagctgcag gcattctcta tggtgaacaa
    22081 taatctgata gcagctggct tcacagggat ttagtcttgg cttgatagcc aatgtccctc
    22141 ttttgtcgta ggtgataggg accgcaggac agctcctaga tgctgaggcc aaagtcttgt
    22201 ggctgggcct caaatgaggt taaaagggaa ggaagctgct atggttatgg tgaaagggct
    22261 agatttaccc ttactttttt gctaggataa tcttttatgc tgttaggccg cagggcttgg
    22321 tgctgcaatg gctgagatgt gtctgtcttt tgtcttagct tttggtgctt gagaagggct
    22381 gggattgagc ttatgctgtg gttgtttttt gatttgctag gtgtcttgac atctgtcgcg
    22441 tttttggtta tactaacgac tagtaaaagg agatattatg accaaaaaac caacacaact
    22501 gattgcctac tcttctattt tggtggcctt tgccatcttg attccgatga taatgcccat
    22561 taagcttatt attggcccgg cttcctttac cctagctagt catctgccct tgtttttagc
    22621 catatttata tccattccgg tagcgatctt ggtggggata ggaacaggtc tgggcttttt
    22681 gctagcagga tttcctatga ttattgttat gcgagccttc tcacacgtgc tttttgcagc
    22741 tattgcggct tttatgctca aaaggcagcc taaatggctg gaaacaccgt taagaacctt
    22801 tgtttttggg attatagcaa atgtgattca tggcctagca gagtttttag tggtttatct
    22861 gatgacagca acagcagcaa ctgatctttc ttatttttgg tcaatgctaa tgcttgttgg
    22921 ctttgggtct ttgctgcatg gtatggtgga tttttatcta gccttattta tctggcgctt
    22981 cttaaggcag aagggtcatc tatcagtgac aagctaggat ttctgtgagt atttatgttt
    23041 tagtagccaa ggctgttaca ggctgaggct cttttttctg aaagcgcttg catttttttg
    23101 aaaaaatgct atactaaaga gtgcgtttgt aaatatacta acaaaaggag atgtcatgaa
    23161 aacaccagaa cagatattag ccgcgacgat tacgattggt gagcataagg ttgcaaagcc
    23221 ttttttggct aaggctattt taggctttat tggcggtgcg atgattagtt tgggctactt
    23281 attgtatgtt aggattgcag ctagtgggct ggagaccttt ggcgcttttt ctagtatttt
    23341 gggtgcttgt gcctttccga ttgggctgat cattattttg atggctggcg gtgaattgat
    23401 cacaggcaac atgatggcgg tgtcggcagc cttttttgca aaaaagatta aggccaagga
    23461 cttgatggcc aattggctgg tgattaccct ttttaatatt ttgggagcct tgttcgttgc
    23521 ctttgttttt ggtcattttc tgggtctgac agctactggc agctttaaag aagaggtcat
    23581 tgaggtggcc catgccaagc ttgctgcaac tcctctacag gctattgttt caggaattgg
    23641 ctgtaactgg tttgttggcc tggcgctttg gctgtgctat ggcgctagtg atgcgacagg
    23701 taagctcctt ggaacctggt ttcctgtgat gacctttgtt gcccttggtt ttcagcatag
    23761 tgtggccaat gcctttgtta ttccggcggc tatttttgag ggtggcgcca gctggatcga
    23821 ttttgcgact aattttgctc tcgtttatgt gggcaatgtc cttggcggtg ctatctttgt
    23881 tagtctcttt tattacaagg cttatgatca ctctaaggaa gcctgattag tgctgttata
    23941 tttttagact gggagacctt attctcagtc ttatttttat attttgtgat aaaataggaa
    24001 acgacgttta aaaaggagga gttgataagc atctaatatg gcatcatgga taaaaaagaa
    24061 aaaagcaagc attcctaggc gaattcatct cctttttttg gtgattgttt ttttgtttgt
    24121 tgccctgatt ttgagattgg cacaaatgca gatttatgag aaggattttt acaaggcaaa
    24181 gctgacagcg tcaaccgttt acaaagtaaa aagctctatg ccaaggggaa ccatttttga
    24241 ccgtaatggg aaggttctag tttctaatcg tatcaaggac gtggtaacct atacgagaag
    24301 tcccaaggct agtgctaagg acattaaggc tttggctcat cagctagctg cttatattag
    24361 ctatcctgag gctaaagtga cagtcagagc caaaaaggat tattatttgg cagatccaga
    24421 ggcttatgct aagacggttc aagccttacc ccaaaaggac aaggtggatc gctttggtaa
    24481 taaattagtc gaagcacaga tatatcaaaa tgcggcagcc tctcttaagg aaacagactt
    24541 gacctattca gaccaagagc taaaggttat tgctattttt aaccaaatga atgcagcagc
    24601 tgtttttagc actgtaaagc tcaaaacatc agccttatct gagcaggata ttgccatcat
    24661 tatggccaat aagtcaaaat taccaggtat ttcagttggg acagactggg agcgtcaggt
    24721 ggaggagaca agccttgctg ctattattgg aagggtctct agtgaggaag ccggtcttcc
    24781 aaaggaagaa gcaaaggctt atcttaaaaa gggctattcg cttaatgatc gtgttggaac
    24841 ctcttatctg gaaaagcaat acgaggaggt ccttcaagga aagcatgaaa tcagagaaat
    24901 caaaacgagc agatctggtg aggttatttc agataaaata gtcgaaaagg gtcagatggg
    24961 gcggaacctg aagttgagcg tgccacttga ttttcaacag ggcgttgagc agatcttgaa
    25021 tcagcacttc cagacagagc tcaaaaatgg tcaggctgct tactcagaag ggatctatgc
    25081 tgtggcgctt aaccctaata cgggagcgat tttagcgatg gcaggtctat cacacaatcc
    25141 caaaaccggt gagcttcaaa aggacgcttt agggactatt actgatgtgt ttacacctgg
    25201 gtctgttgtc aagggggcga ccttggctgc cggctggcag gctggagtga ttcaggggaa
    25261 tcaggtcttg attgatcagc cgattcaatt tggtggctcc cagccgatta attcttggtt
    25321 taccagcggt cagcacccta ttactgctag tcaggcgctg gaatattcat caaatactta
    25381 catggttcag gttgccttaa gaatgatggg gcaggattac gtgactggta tgaccttggc
    25441 caatactggt atgaaggaaa ccatgaaaaa attgcgggca gcctatgccg aatttggcat
    25501 gggagtggca actggcgttg atttgcctgg cgaatccagt ggctacctca tagatcaata
    25561 taatactgca aatgttttga cagaggcctt tggtcagttt gataactata caaccatgca
    25621 actggcccaa tatgtctcaa ctattgctaa tggcggcagt cgccttgcgc ctcacattgt
    25681 agaaggcatt tatcaggata atgaccagtc aggaccaggt aagctaagta aggctattga
    25741 gactaccttg ttaaacaagg tgcacttagc tgctgatagt ttagcgatta ttcaggacgg
    25801 tttttatcag gtggtcaata gcggtagtgg ctatgctaca ggtagggctc ttgcaggagg
    25861 tcctgttacc attagtgcta aaaccggtac cgcagaaacc tatgctaagg ataaaaatgg
    25921 tcaggcttta tctaccttta acttgaatgt tgttgcctat ggtccgagtg ctagtcctca
    25981 aattgctgtt gctgtcatgt atcctcatgc gacagactct ctagccaagg cacatcaata
    26041 cgtggctaag gatatcatta atttgtacat gaagatgtat aaaaaccaat aaaggagaaa
    26101 cgagtgcttt accctatacc aatcgcaaaa ttaattgaaa gctattctaa attaccaggg
    26161 attggtgtta aaacagcgac aagattggct ttttacacca ttggaatgtc tgatgaggat
    26221 gtgaatgatt ttgccaaaaa tttattagca gctaagcgag aattaaccta ttgctctatc
    26281 tgtggcaatt tgacagatga tgatccctgc catatttgca cagatagcag tcgggataaa
    26341 gagatcattt tagttgttga ggattccaag gacgtttctg ccatggaaaa aattcaagaa
    26401 tatcatggct attaccatgt gctgcatggc ttgatttctc ccatgaatgg ggttggccca
    26461 gatgacatca atctaaagag cctaatcacg cgtttgatgg ctggagaggc aacagaggtc
    26521 attgttgcaa cgaatgccac agcagatgga gaggcgactg cgatgtacat ctcacgtctc
    26581 ctaaagcctg ctggtatcaa ggtgacgcga ttggctagag gcttggcagt aggatcagac
    26641 attgaatatg ctgatgaggt aaccctgctg cgagcgattg aaaatcggac agaattatag
    26701 cttagcccat tttcagctct ctgtcattag cccttatgcc atgtgataag gccataaagg
    26761 aaggcagatt ttgtcagagt cttttgaaaa gcaagctcgt ttttgttata ataagtggta
    26821 gtctaattca gatagggaag gttatcaatg tctaaacaaa ccttaatttt attatacgga
    26881 gggcgttcgg cagagcgtga agtatcagtg ctttcagctg agagcgtgat gagagcagtt
    26941 gattacacca aattttttgt taaaacctat tttatcagcc agacaggtca gtttatcaag
    27001 acacaggaat tctctagtcg gccgacctta acagaaaggc tgatgaccaa cgacactatt
    27061 aggctagagc agcagataag gcctagtgat atctacgagg agggggctgt tgtttttcca
    27121 gtcttgcatg gccctatggg agaggacggt tctattcaag gctttttaga ggtgctaaaa
    27181 atgccttatg tgggaactaa tatcctctca tcaagtgttg caatggataa gattaccacc
    27241 aaaagggtcc tagagtcagc tggtatccca caggttgctt ataccgttta tattgagggg
    27301 caggatttag acaggtgtct ggcagagact gaggcagtct taagctaccc tgtgtttgtt
    27361 aagccggcca atatgggctc atctgttggt atttctaagg cagaatcaga ggaggagttg
    27421 cgtgcagcta tcctgttggc cttgacgtat gacagtcgta tcctgattga gcaaggggtt
    27481 ttggcaagag agattgaggt tggactgctt ggtaataccg atgtcaaatc aacccttcca
    27541 ggagaggtag tcaagaatgt tgacttttat gattatcagg ccaaatacat tgataatgag
    27601 atcacaatgg ctattccggc agctattgac gaatcagcta tgacaagcat gcgtacctac
    27661 gcagaaacag cctttaaggc tattggtgct tgtggcctgt cgcgttgtga tttcttcctt
    27721 ggtcaggacg gtcagatcta cctcaatgaa ttaaatacca tgcctggctt tacgcagtgg
    27781 tccatgtatc ccttgctctg ggagcatatg ggactgagct atgctgagct tattgaggag
    27841 ctagtcagat tagcacagga aatgtttgaa aagcgtgaag ggcatttaat ataagagaca
    27901 aaggacggaa ggagatatag caatcctctg tcctttcgtt tggcctgatt ggtagcgttt
    27961 tttggtcaga agcctttaaa gccctatcgt ctacggttgg ctgtgccagc tttagcctgt
    28021 ctatgaagga tcagcctgta ggcataaagt gaaatagaaa gaatattcct aatatgttat
    28081 gctata
//
LOCUS       DARYUW010000027        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYUW010000027 DARYUW010000000
VERSION     DARYUW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(298..813)
                     /locus_tag="TVW11_001051"
     CDS             complement(298..813)
                     /locus_tag="TVW11_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1365156.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TVW11_001052"
     CDS             complement(815..2326)
                     /locus_tag="TVW11_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1365157.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TVW11_001053"
     CDS             complement(2316..3041)
                     /locus_tag="TVW11_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1365158.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TVW11_001054"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TVW11_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TVW11_001055"
     CDS             complement(4136..4642)
                     /locus_tag="TVW11_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365159.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TVW11_001056"
     CDS             complement(4644..5570)
                     /locus_tag="TVW11_001056"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365160.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TVW11_001057"
     CDS             complement(5712..6134)
                     /locus_tag="TVW11_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365161.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TVW11_001058"
     CDS             complement(6457..6717)
                     /locus_tag="TVW11_001058"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365162.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TVW11_001059"
     CDS             complement(6732..8540)
                     /locus_tag="TVW11_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365163.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TVW11_001060"
     CDS             complement(9181..10080)
                     /locus_tag="TVW11_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1365164.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TVW11_001061"
     CDS             complement(10092..10901)
                     /locus_tag="TVW11_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1365165.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TVW11_001062"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TVW11_001062"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1365166.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TVW11_001063"
     CDS             complement(11736..12476)
                     /locus_tag="TVW11_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365167.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TVW11_001064"
     CDS             complement(12480..13778)
                     /locus_tag="TVW11_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1365168.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TVW11_001065"
     CDS             complement(13790..15136)
                     /locus_tag="TVW11_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1365169.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TVW11_001066"
     CDS             complement(15581..17026)
                     /locus_tag="TVW11_001066"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1365170.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TVW11_001067"
     CDS             complement(17628..18341)
                     /locus_tag="TVW11_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1365171.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TVW11_001068"
     CDS             complement(18469..18975)
                     /locus_tag="TVW11_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1365172.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TVW11_001069"
     CDS             19358..19636
                     /locus_tag="TVW11_001069"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365173.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TVW11_001070"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TVW11_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1365174.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TVW11_001071"
     CDS             complement(21225..21671)
                     /locus_tag="TVW11_001071"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1365175.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TVW11_001072"
     CDS             complement(21873..22640)
                     /locus_tag="TVW11_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1365176.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TVW11_001073"
     CDS             complement(22802..24598)
                     /locus_tag="TVW11_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365177.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TVW11_001074"
     CDS             complement(24598..26307)
                     /locus_tag="TVW11_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365178.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TVW11_001075"
     CDS             complement(26300..26749)
                     /locus_tag="TVW11_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1365179.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TVW11_001076"
     CDS             26959..27978
                     /locus_tag="TVW11_001076"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1365180.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8373 a         6755 c         5154 g         7751 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagatag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggc accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt ggagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYUW010000028        27682 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYUW010000028 DARYUW010000000
VERSION     DARYUW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27682
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(1..234)
                     /locus_tag="TVW11_001077"
     CDS             complement(1..234)
                     /locus_tag="TVW11_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1365181.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
     gene            403..1200
                     /locus_tag="TVW11_001078"
     CDS             403..1200
                     /locus_tag="TVW11_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1365182.1"
                     /translation="MQCSSTSNRLKQLMSERNLRQVDILEKSKPFQKQLGVKMGRSTL
                     SQYVSGKSVPAQRQLYLLSKTLNVSEAWLMGYDVAIERIPDEKRGATTEISNQPEIVS
                     IYNQLEQPRQEKVLDFAKEQLEEQKHEQNNLFEVTGISYAAAASGLGRGFDVDDYDTY
                     TVYTDEEPPRYDYAIGVRGDSMLPTYEAGDMLYLVDKGMSNYSGQLCVIAYNGQTYFK
                     KVYTEANGLRLVSLNKKYDDIFIDYPPAEDTYIKIFDVIGSFVPVEM"
     gene            1324..2769
                     /locus_tag="TVW11_001079"
     CDS             1324..2769
                     /locus_tag="TVW11_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1365183.1"
                     /translation="MFTTNKVAIYVRVSTTNQAEEGYSIEEQKDKLSSYCNIKDWSIY
                     NIYTDGGFSGSNTARPALENLIKDAKKKKFDTVLVYKLDRLSRSQKDTLYLIEEVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLAVFAQLEREQIKERMQLGKLGRAKSGKPMMWS
                     KPAYGYIYHKESGELIVNELEAIVVREIFKSYLEGMSITKLRDKVNEKYPKTPAWHYR
                     IIRGILANPVYCGYNQYKGQVFPGNHEPIISEEVFNKTQEELKIRQQTAAEKFNPRPF
                     QAKYMLSGIAQCGYCHAPLTIIMGMIRKDGTRFIRYECKQRYPRKTKGVTVYNNNEKC
                     HSGAYEKSDIEEYVLKEISKLQNDKDYLDEIFSDSNTETIDRESYQKQIEELSKKLSK
                     LNDLYIDDRITLEDLKKKSYEFTSMRTLLETELENDPALKKQKRKDDMKKILSAEDIF
                     SMDYEGQKIMVRGLINKVQVTADDVFIKWKI"
     gene            complement(2850..3836)
                     /locus_tag="TVW11_001080"
     CDS             complement(2850..3836)
                     /locus_tag="TVW11_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1365184.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(3817..4755)
                     /gene="tadA"
                     /locus_tag="TVW11_001081"
     CDS             complement(3817..4755)
                     /gene="tadA"
                     /locus_tag="TVW11_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1365185.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(4937..5584)
                     /locus_tag="TVW11_001082"
     CDS             complement(4937..5584)
                     /locus_tag="TVW11_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365186.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(5586..7589)
                     /locus_tag="TVW11_001083"
     CDS             complement(5586..7589)
                     /locus_tag="TVW11_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1365187.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(8126..8491)
                     /locus_tag="TVW11_001084"
     CDS             complement(8126..8491)
                     /locus_tag="TVW11_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1365188.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(8552..9598)
                     /locus_tag="TVW11_001085"
     CDS             complement(8552..9598)
                     /locus_tag="TVW11_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1365189.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(10162..10716)
                     /locus_tag="TVW11_001086"
     CDS             complement(10162..10716)
                     /locus_tag="TVW11_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365190.1"
                     /translation="MRLKKLIYSSIAALAILTYGTISANADASIPEIDQTEVITILKS
                     DGYLNIDEGTQEVTITEKYKQAVLSSIDLDRQEAIFTENSVTIRDIFSPRSFTGVNKI
                     VFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANA
                     AGRGVIVAFVGTFPRGVIHWVASQ"
     gene            10985..11195
                     /locus_tag="TVW11_001087"
                     /pseudo
     CDS             10985..11195
                     /locus_tag="TVW11_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11287..14922)
                     /gene="rpoC"
                     /locus_tag="TVW11_001088"
     CDS             complement(11287..14922)
                     /gene="rpoC"
                     /locus_tag="TVW11_001088"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1365191.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(15013..18579)
                     /gene="rpoB"
                     /locus_tag="TVW11_001089"
     CDS             complement(15013..18579)
                     /gene="rpoB"
                     /locus_tag="TVW11_001089"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1365192.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            complement(18841..21141)
                     /locus_tag="TVW11_001090"
     CDS             complement(18841..21141)
                     /locus_tag="TVW11_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1365193.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            21246..22502
                     /locus_tag="TVW11_001091"
     CDS             21246..22502
                     /locus_tag="TVW11_001091"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1365194.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(22537..23346)
                     /locus_tag="TVW11_001092"
     CDS             complement(22537..23346)
                     /locus_tag="TVW11_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1365195.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(23339..24058)
                     /locus_tag="TVW11_001093"
     CDS             complement(23339..24058)
                     /locus_tag="TVW11_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1365196.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKSRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(24061..24504)
                     /locus_tag="TVW11_001094"
     CDS             complement(24061..24504)
                     /locus_tag="TVW11_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1365197.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(24574..25425)
                     /locus_tag="TVW11_001095"
     CDS             complement(24574..25425)
                     /locus_tag="TVW11_001095"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1365198.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(25640..26164)
                     /locus_tag="TVW11_001096"
     CDS             complement(25640..26164)
                     /locus_tag="TVW11_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1365199.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(26658..>27682)
                     /locus_tag="TVW11_001097"
     CDS             complement(26658..>27682)
                     /locus_tag="TVW11_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1365200.1"
                     /translation="PVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGP
                     QGPVGPAGPRGERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQ
                     GPTGPTGKPGERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRG
                     EKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGE
                     QGQRGEKGEQGQRGEKGEQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVP
                     KTSEQQSASPKVPAPKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLT
                     LKRKNN"
BASE COUNT         8390 a         6519 c         5199 g         7574 t
ORIGIN      
        1 ttagttttgt tcatgaatat gaacattttg cttaaaaaaa tattctccta catcgttttc
       61 gttgatatct aactcttgac aagcttgcgc aatttctttg cttctccagt ctactttatt
      121 attaagtttt aaagatagcg agcgctcaga tagccctaaa gccaaggcaa agttgtactg
      181 tgtgccgaac ttctcaacga tccttccgct gagttttgaa taatcaaaaa ccataggaac
      241 ctcctttctt ttttgttcac gttcatgaac tttatgcttt tatgttacac tttgttttga
      301 actttgtcaa tacacaaagt tcattttttt gaattttttt attgaacttt tgttcaagat
      361 gttttataat taacctataa acatcgaaag gaatctactt ttatgcaatg tagttctact
      421 tcaaatagat taaaacaact gatgtcagaa agaaatttaa ggcaggttga tattttagaa
      481 aaatcaaaac cttttcagaa acaattgggg gtaaagatgg gcagaagtac tctttcgcaa
      541 tacgttagtg gcaaatctgt tccagctcaa cgacaactct atcttttatc taaaaccctt
      601 aacgtaagcg aggcatggct gatgggatat gatgtagcca tagagcgcat acctgatgaa
      661 aaacgtggag ctacgacaga aatatctaat caacctgaaa tcgtttctat ctacaaccaa
      721 ctagaacaac ctagacaaga aaaagtcctt gactttgcta aagagcagtt ggaagaacaa
      781 aagcatgaac aaaataacct ttttgaagta acaggtattt cctatgctgc ggctgcaagt
      841 gggctgggta gaggttttga tgttgatgac tacgatacct ataccgtcta tacagatgaa
      901 gaaccaccac gctatgatta tgctattggt gtccgcggtg acagtatgct accaacatac
      961 gaggctggcg atatgctcta tctcgttgat aagggcatgt caaattactc aggtcagctt
     1021 tgtgtaattg catacaacgg tcagacctat tttaaaaagg tttacaccga agctaatggt
     1081 ctacgcttag tctcacttaa taaaaaatat gatgatattt ttattgatta tccaccagca
     1141 gaagatacct acatcaagat ttttgatgtc attggtagct ttgtcccagt agaaatgtaa
     1201 aacaaaaagc cccacactct ccccgaccaa agtttgagtg tgaggtatct cgtacaataa
     1261 agaataggca ttaaatggcc ctctttactg tacccatttt atcaaaaaag aggtacaaaa
     1321 acaatgttta caacaaacaa ggtagcaatt tacgtcagag tttcgactac taaccaagct
     1381 gaggagggct actctattga ggagcaaaaa gacaagcttt ctagctactg caatatcaaa
     1441 gattggagca tttacaacat ttacacagac ggtggctttt cagggtcaaa tactgcgcgc
     1501 cctgccttgg aaaatctcat caaagacgct aaaaagaaga aatttgatac tgtccttgtc
     1561 tacaagctag accgtttgag ccgtagccaa aaggacacgc tctatttaat cgaagaggtt
     1621 tttataaaaa acggtataga atttttgagc ctacaagaaa attttgacac atctactccc
     1681 tttggcaaag ctatgatagg gctacttgca gtattcgctc agttggagcg tgaacaaata
     1741 aaggaacgta tgcaattagg taaactaggt agagccaaat ctggaaaacc aatgatgtgg
     1801 tctaaaccag catatggcta tatatatcac aaagaatctg gagaactcat tgtcaatgaa
     1861 ttagaggcta ttgtggtcag agagatattt aagtcctatc ttgagggaat gtctattacc
     1921 aagctcagag acaaagtaaa tgagaaatac cctaaaactc cagcatggca ctatagaatt
     1981 atcagaggca ttctagccaa tcctgtctac tgtggttaca accaatataa gggacaggtg
     2041 ttccctggta accatgaacc tattatctct gaggaagtct ttaacaagac tcaagaagaa
     2101 ctcaaaataa gacagcagac agcagctgag aaattcaacc ctagaccatt tcaggctaag
     2161 tatatgctct caggtattgc ccaatgtggt tactgccacg ctccgctcac aattattatg
     2221 ggcatgatta ggaaagatgg tacaaggttt ataagatatg aatgcaaaca aagataccca
     2281 agaaaaacaa aaggtgtaac agtctataac aataatgaaa aatgtcactc tggagcttat
     2341 gaaaaaagcg acatcgagga atatgtcctt aaagaaatca gcaagctaca aaatgacaaa
     2401 gactacctag atgagatatt ctcagactct aacactgaaa ctatcgatcg tgaaagttat
     2461 caaaagcaga tagaggagtt atcaaagaaa ctcagcaaac taaatgacct ctatatagat
     2521 gaccgtatca cactagaaga tttgaaaaag aaatcttatg aatttacaag catgaggaca
     2581 ttacttgaga cagagctaga aaacgatcca gcactcaaaa aacaaaaacg aaaagacgac
     2641 atgaagaaga tactcagtgc tgaagatatt ttttcaatgg actacgaggg tcaaaaaatt
     2701 atggttagag gtcttataaa caaagtacaa gtcactgctg atgatgtttt catcaagtgg
     2761 aaaatataaa caattttact atcctgtatt tccagtaaag tgaaggcctg aacaccttga
     2821 tcttttaaga ttgataatct cattttcatt taaaaaacat ctcccatctg ttgataaatt
     2881 ggtaataaaa tagcagcata aatcatcaca ataaccacag caaccactaa aaaaataatc
     2941 ggctggatcc attgtgttgc ccgattaagc tgactaaaaa aggtctccca gctttcttgg
     3001 gaatagatat ctaattcctg accaagcttt gatttgatgt caccatattc aatcattagg
     3061 cttagctcct ttttaaaaaa gggataagct gcaacccttt gatgaaagga ttggccagct
     3121 agtagactct gcttgatatc cttggcaagc tctcgcatga gctgtgactt ttcgtttgac
     3181 atcatctcta aaatggtgat taattctaag ccttgtccga tgaggttgcc ccattctcta
     3241 gcatagtagg ctgtcaaata ttgccgcaat aaggacccaa tgataggata atagctcagc
     3301 tgactaaata gttttagccg actacaggac ttggcatata ggtaaaaaga gccaattagc
     3361 aacagcacaa gcaaacaaaa acctaagaaa taatgaggca aatgaagcaa caagtcagtc
     3421 aaggtatttt gactctctag ctgagggatt aggtaatgac gcaagcctag catgataacc
     3481 actagaaaac ccaaaagtat aatcggataa gtgactgcct cgatggtctt tcgcttgatt
     3541 tggcgaaatt gactcagata gtcctgaatt ttttccaagg ttagcttgat attgccatgc
     3601 ttatctgcca gattaatttg tgtcataaca gcatcagagt aacctaaggc tgctagcatg
     3661 tcagcaaggc cgttgccctt taataggctt gcttccatac ttgtaacata gactggcagt
     3721 agcagctggc tttttctcaa aaaagcaatg acctctgtca aattaaagcc gttagacaat
     3781 aggttataga gcaattggat aagcttttcc tgctgcttac tggataattt tttcaagcct
     3841 tgcctgcctg gtattgagat gtccctccgc aagaagctga tcaatctgct gattccaccg
     3901 gttggcttga tgatgttcaa attccttttg tgcacaatca attaaagcac ctccactaat
     3961 aaatcgctgg taagcaacca ttgctagact attatccaat tctgccctag aaatgcctaa
     4021 ttctagcagt ctagcgtaaa cgcctgaaat actctttgca tggacggttg aaaagaccat
     4081 tgctcctgtt aggctagccc taataaccgc tctagcagtc tgtgtatctc taatttctcc
     4141 gataatcaac acatctggac gatgacgcaa ggaaagctta atcagattat cgtatgtcat
     4201 gccaatgcta tcgttaacct gtaattgcag gagctggtca ttttttattt ccacaggatc
     4261 ctcaatactg atcacctgaa gctccttgca atagtcagag actagctgat acatcagggt
     4321 tgtcttacct gatcccaccg gtccagaaaa gaggtaaagg cctctagctc caatagctga
     4381 tgtgactcgc tctaaaccat caaaccaata cctgagctgg cgttgatgat gatacaagag
     4441 acgaataacc aagctctcct gtccctgata atcacccaca gctgataatc gtagagacac
     4501 cttagtgtca tcaaggtcgt agtcacaagc accgagctga cagcgtcttt tttcgcccac
     4561 attcattcct gcaacgaact taaagtgact aataagatta gccatccgat cactttcaca
     4621 aacatctatt agcctcctat catcacctac cctcatcaaa agctcatagc ctgtccccct
     4681 tggtagtata taaatatcct gagcctgcaa ttcttcagcc tgcctgataa gccgcttggc
     4741 taattcttga atcattctta cctcctcact aagactattc gaaaaataaa aaaaatagcc
     4801 tcaagaaaaa ggccattttt tgataaatgt ttaacatcaa gtaaggaatt cagcacgcta
     4861 caaacagcgc agaatccttt tgcgatgcta tgatgacaag gtcaagcctt aatcacttag
     4921 ctagtccagg ctttatttag agcctggtga ggctgctaag ctgatcaaca gagatgacct
     4981 catctgccat ttcccaaatg cttgggctgt gggttgcgat gataattgtc cgatttttat
     5041 gccgaagtga cagcaaaata gccataattg ccttagaagc ctctggatca atagaagccg
     5101 taggctcatc agctaaaata aagggaggat cttttagcat caccttagct agggcaacac
     5161 gctggtattc accaccagac aattcaaaaa caggcttttc taagctcaga taatccaagc
     5221 caactgccct tagggcttct aattcccttt gccggccttc ctccttgctt attttttgac
     5281 caattagccc tagcttcaaa ttatcagcaa tcgtctgact ctccaacagc ccaaaatgct
     5341 gaaataggta gcccaattcg tgacggaaaa aatcgctgga tctgtatgtt ttcaagtttt
     5401 ttccacgaaa gaaaatctca ccctgataat cctcaagagc tgccagcata ttcatcaagg
     5461 ttgtcttacc actaccgctt gacccaatca gggcataaac ctttccagac tcaaaggtca
     5521 ttgacaaatc agaaaataag acacgatcac caaagcattt actaaccttt tctaatcgaa
     5581 tcatactaag ctcctttcaa aatcagcagc gacatcttat tttctattct catttgccga
     5641 tatagtagca atatggcatt ccctagaaat aggaagaaaa ccagcaggca cataagagga
     5701 ttctgtgtta acagggcact aatcaccaat ccaacaaaga aaacaagcag ctgcgacagc
     5761 aaataacgac gatgcagctc aaaaaatcta agaccagaga cgcgcttaat gaaaatatcc
     5821 cgtctaaatt cttcaaagta gagaaggttc attgtgttaa acatcaacat agaggtcgct
     5881 atccctaata tagctcctgc aatcatcaac caaatctccc tacgaagatt gttcaacaat
     5941 gtctcataaa tgcgatagcc agtttttagc tctcctaccc agttctcaat accgttttgc
     6001 ttgatgagcg tttgagtatc tgccaactga tcgaaaagga aataattttg taaagcaacc
     6061 tcccaaaagg cataggcttg ttcgccagtt gacttaggcg tcaaaacaac aataatggga
     6121 tcccttaaaa actgctgata ggatatcggt gttgtgttat aaagaaagcg ttcctggcct
     6181 gtctttgtat aagaaacagt agcagtcatc ggctgatgac cctcacctga agcaagccca
     6241 gttacagctg attcaaagac cgattggtac tgtgcagcct gtgttttcaa atgctctggt
     6301 aaaagaagga caaattctcc aagggacagc tgattgattt tttcactaat atcaggtgcc
     6361 acctcaactt tttggtgctt cacatattga ggcgttacaa gcagcacatt cccttgtgga
     6421 ctgtaatcat tccaactaga agaggctgtt agcatagaga ggcctgattg caggtcgcgc
     6481 tcgactaggt aatgacgaga caggatcgct ccatgctctg aaacagcctg atccataaca
     6541 tgaaaccaag tcttttgttt ggcaatagct tccttcgtat ttccaatatc taagccatca
     6601 cgtcctatta aaagagtaac cagcctatcc tcttgtagcc aagcagcctg cccctgcttc
     6661 tgctgtcttt cagcctggac ataaagaagg gtccggctag cgccaaagga aacaaccagc
     6721 actgccaaca attgggcaat taaaatcaag ctaatgatac ctctgacagg tatctgacct
     6781 ttaatcacct gcatcaaatg cactctttta atcccaatta caaataaacc agcaaagaaa
     6841 agggcaatag ctatcagcaa aagattatag caaacaagac ctatcccaat caggtaaaga
     6901 acaagcggtg aaaaagacat aagctgactc ataatagccg ccaggctaag gccaagtagt
     6961 aggcctagac agcaatagca cacatcagac ctgattggat aaagaaagat ctgccagcga
     7021 cgttcacctg aaatcaagcg gatacccact gctcgcagcg tgcgaatatg gccaatcaag
     7081 gtcaaagccc caaaggttag acagaatatc acaatcccta aagcctgaga accactgcta
     7141 aaaatcaaaa cgagagtccc taaaaatgaa ggcttcagcg ctgtcatttt ggtcataccg
     7201 agcccagcta atgtgtctct tagtcgctct acagtcaagc cgcctttaag aataaagtaa
     7261 ttattctcca cactaagcct tgatggttcc tcaataacct tttcagctag tccaccaggt
     7321 agctttccct tgccaaataa ggtataggtc acaataggtg taccttctgg ccctggctcc
     7381 tggtgctgca ttgcaattaa gctgtctgtt tcatctgcta gacgggttaa gcctgcttca
     7441 acctgattat agcttgcctt aggcgaagca tctaaaacaa caacagacgg ataataatga
     7501 gaaacaaagg tatctgacca gatcgtaaat acccaaacca aaaagaggct aactagtata
     7561 ttagacaata tgataaacag tctcttcata acccactcct taccttaaaa gggacggagt
     7621 ctctccgccc ctaataaaca cacactgacc tgcctatttc cctgcatcaa aggtcacgtg
     7681 ctctccaaaa ttagtattga taaaagcata ggagtagtaa ccagcaccag accatgcacg
     7741 cctctgatta tcacgtcctg agctctccac aaaggaccgg tgagaagagg tcagaaggtc
     7801 acctattgaa aacgccttca atcataaagg acatggcgat taccacaata ccactcaaat
     7861 cattaactat ttaacaaaaa tataccatat tctgttaacg tttacaatgt tatatttaat
     7921 ccatttttat aaaaaaataa cattatatca tgcctcaaat gattttatca taatgaggct
     7981 cgctatgttg ttttctctat cccaatcagg cactgctaga ttagacatct ttccagacaa
     8041 caaaaatagc ctaaggtcag ctctctaatt agctgatctt aggctatttg agtgataata
     8101 gatttgactg atagctgtaa gcctctcaga tgcttaattt acagctaagg gaggcttgtg
     8161 ggcagtcatt tctttgctca aaatatgact gataatgatg ctttggcaca atgtctctat
     8221 cctttagcaa taaaagagag tgatactgct gcagctcctc atcgcaatcc tcacaccatc
     8281 ttcgctcatc ttccctccaa aaggtagcca ataagctttt ttgactgtgg tagctgggat
     8341 agctcttttt catgcgctgc cattcttcct caaaataagc cagtgcagca ggccagctgt
     8401 caaacgattt ctcctgaaca atatcgtctt gccaaccatc tataaaccac caaggctccc
     8461 agtctccata catttcaatc acttgataca tgttctcatt tcctctattg cctattatag
     8521 ccgaagaaag atatttttaa aaaacatctg ctcactgcct tttaagatag gccttggcat
     8581 gagcttgaga acgtaccagc agcataaggg cctctgagca aagatgagta gctagcaggg
     8641 tcatgagaaa gaccagtttc ccttttgtgg ccggggcaag ctggtagggc cttagcagaa
     8701 atagcgaaca ttcgataaac attgggtgca agaaaaaata ataatagctt agctttttta
     8761 atttagctaa agaatattta gacagaaggc tgatacggac actggcattg aataaaaagg
     8821 tagtaaacag cgcagaaagc aagaagaaat ttttatccag accctgatga tggtaaataa
     8881 gcaggctttc caaggccaat aagatcaggc aaacagccgc ctttctcata tacctctgag
     8941 aaaaaagcga cgatgaaaag tgatcataga gcaagcagcc cgcacaaaga taagcagggg
     9001 tgtaaaaaat accattgcga cttgtttgaa aaatgtgcat gtagcctgtc agcaaaggct
     9061 caaaaggcgt cgagcttaaa aaatgagaat aggtttccat actccctagt aaatacaagc
     9121 ccgccactat gatgagcgtt accttcttac caaaggtctt cagagaaagc tgaacaagca
     9181 cccaccccag ccataaagca ggaatatacc acagatgata gcacatccca aaataactaa
     9241 gggctaaaca caagccaagg ggaagataat gcttaggcag acgaagcgac tcaaaaaagg
     9301 cataagcata agggaggtaa atcagagacc aaagcaaata ggtttttagt atttgcttga
     9361 agtactgctt ttcccgattc gcctctctaa ggcggcctct tagaaaaaag gcggtacaaa
     9421 tgagaaaata aggcaccgcc attcttccta aaaagctttt caaaaagaaa tgcagcggct
     9481 catactgaaa cagcctaccg ctatgaataa caataaccat tatggcaaaa cagtattgta
     9541 acaggcttac cacagaggta ttgaggctgt cagtgacttt ctggctctct tttgtcatca
     9601 attcaatcac tttcttttaa gagattaata tacgtataac ttttagtatt tatcgcattt
     9661 gtctctcatt ttgattaata ttgtttttat catagcgtaa tataaccaat taatctaatg
     9721 attttagcat aacaaaagga gctaaggcta gctcctgaac atcacaaaag agcagacgaa
     9781 cttcatctcc tctcgtgctt agatataagc cacccactac agttaacatg gagccataaa
     9841 acgaaggaat taactccttc gttttctttc aatttttctt ggaatatttt tatagacttt
     9901 tcttacggat atagtaagaa taactaccag caataatgac ataattcaat aaaagacata
     9961 attaatcaca acttgattgt ctttctaaca aatccattcc ctgcctggat cattagtata
    10021 cgaaaaaaat gataggtaaa actataccca ataggcagaa aaaaactttc caaaaaatag
    10081 tattattttt aaataattta tcaacaaaca ccaataatat caaattaatt gctaaacaca
    10141 gtatttttaa atataatgct atcattgtga agccacccaa tgtatcacac ctcttggaaa
    10201 agttcctaca aaggcaacaa ttactcctct tcctgcagca ttagcataag atattgatgc
    10261 agacacaact cctaaagcgg ctgcaagtac cttagatact atagggtctg gaataagacc
    10321 tgacaaagca gttgatcccc agcctagtgc agataatcta ttcgcattgg tactatctaa
    10381 ataaagatca tagcctttcc aagtaaaaac aattttattt accccagtaa atgatctagg
    10441 actaaatata tctcttatag taacagaatt ttcagtaaaa attgcttctt gtctatctaa
    10501 atcaatagaa gataaaactg cttgtttata tttttctgtt atagtaactt cttgagtacc
    10561 ttcatcaata tttaaatacc catcagattt taaaatagtt attacttcag tttgatcaat
    10621 ttctggaata gaggcatcag cattagccga aatagtaccg taagttaaaa ttgcaagcgc
    10681 agcgatacta gaataaataa gtttttttag tctcataatc tactcctttt taatctctaa
    10741 aattaaaaca aacaatcttt accggtaata gttaatttta ctactaaaaa taaactcctt
    10801 tctggtaaaa tgaaccacct aagaaaccta catgtacaga ataacatata ttttccttaa
    10861 aaataagact atattttaaa aaaacaaatg ataaaattaa attttggaag ctttttttat
    10921 aataaaataa tttatcgatt tttccactat taagttattt ttgattaaca tttttaaaat
    10981 agttttgtct atctacatac aatataaaga ctatatcact aatgccattg aactacctta
    11041 ttctaacgcc aagtttgaag cgactagcaa actgatcaaa gacatcaagc gcaatgcatt
    11101 tggattcaga aacgttgaca atttcaagaa acttatctat gcttgctttg aacatgacaa
    11161 aagagaagac gaccttcgtc tcctctcgtg cttagttatc agtcacctac tatagttgac
    11221 atggagccca attaatctaa tgattttagc atgataaaag gagctaaggc tagctccttt
    11281 tatttcttat tccttaataa ttgctggctc ttctgtagct tcagcttctt cgataacctc
    11341 aacctcattg atagcttgcg gttcaatgtt acggtaacga accataccag tacctgctgg
    11401 aatgatctta ccaatgataa cattttcctt aagccccaat agatggtctt ttttgcctcg
    11461 gatagcagcg tctgtcagca cgcgagtggt ttcctggaag gaagctgctg ataggaatga
    11521 gttagtctca agtgaggctt ttgtgattcc cataagcact ggacgagagg tcgcaggaat
    11581 acctccagag ataacaatct ccttattggc atctgtaaag tctgcaatat ccattaaggt
    11641 tcctggcaga agatctgtat cacctggatc catgacacgt accttgcgaa gcatttgacg
    11701 aaccataacc tcaacgtgct tgtctccgat ttctacccct tggctgcggt aaaccttttg
    11761 aacctcagca agcaagtagg tctcaactga caaggtatca cgaacctcaa ggaggtgctt
    11821 aggctggatt gacccttctg taagggcagc tccacgattg acctcatcac caacctcaac
    11881 cttcatacgc gctgtaaatg gcacaacata ttcacccatg cctgttttac cttgaacgta
    11941 gaccttctta gtacgagttg atgcgtcctc ttcaatctca ataacagtcc ccttaacctc
    12001 tgtgataact gcttcccctt tagggttgcg cgcttcaaag atttcttgga tacgaggaag
    12061 accctgtgtg atatcggtat tagaggcaac ccctcctgtg tggaaggtac gcatggtcag
    12121 ctgagtacca ggctcaccaa tagattgggc agcgatagta ccaacagcct caccaacctc
    12181 aaccgcatca cctgtcgcta ggttgatacc gtaacagtga cgacacactc catgacgagt
    12241 agcacaggta aatactgagc gaatggtaac ctcttcaaca ccagcatcaa caatcttgcg
    12301 agccatgtcc tcagtgatta attggtcagc accaatcaat acctcaccag tttcagggtg
    12361 cttgactgat ttacgagtgt atcgaccctg caagcgctcc tcaagtgttt cagtgacttc
    12421 cttgccatct gtgatagctc gaataagaag gcctcggtct gtaccacaat cgtcctcacg
    12481 aatgatgaca tcttgcgcaa catcaactaa acgacgtgtc agatagcctg agtcagctgt
    12541 cttaagagcc gtatcagtca tacccttacg agcaccatga gttgagaaga acatttccaa
    12601 aacagacaag ccttcgcgga agttagacag gataggaagc tccataatac ggccattagg
    12661 agcagccatc aagccacgca taccggcaag ctgcgagaag ttagagatgt taccacgcgc
    12721 tcctgagtcc atcatcataa cgattgggtt cttaggatcc tgtgtttcaa tcagacgctt
    12781 ctcaagggct tcttttgcct cgcgccatgt tgttgtgact gcaacatagc gatcatcatc
    12841 agtcatcaag cctcgacgga aggccttatt aatttcctca acacgatggt gagcagcctc
    12901 gatgatctca gccttgttgt caataaccgg aatatcagcg atcccaaccg tcaagcccgc
    12961 aagggttgaa tgatagtagc caaggtcctt caagcggtca agaaaggccg atgtttctgt
    13021 tgtacggaaa cgcttgaagg tttccgcaat gatgttacca agatttttct tcttgaaggg
    13081 cacattgatc ggtaagctat caataacctc ctgaatattc tgacctggct tcaagaaata
    13141 tttatctgga gtgccctctg tcaagttagc attatttggc tcttggaggt aaggaaggtc
    13201 ctctggcatg atgtcattaa acaagatctt accgaccgtt gtcaccatga ttttgtgtct
    13261 ttgactatcc ttccaaagct tgcttggcat actgtcaaca gcaataccaa cacgactatg
    13321 aaggtgaaca tagccattac ggtaagccat taccgcttcg tccttgtcct taaagaccat
    13381 accttcgcct tcacgaccag catcttccat tgttaggtag tagtttccta gcaccatatc
    13441 ctgagaaggt gttacaactg gcttaccgtc cttagggtta agaatatgct cagcagcaag
    13501 catcaacaaa cgagcctctg cctgtgcttc ctctgaaagc ggcacgtgaa tagccatttg
    13561 gtctccgtca aagtcggcat tgtaggcctc acacacaagc gggtgaagac gaagagcctt
    13621 accatcaata agcaccggct caaaggcctg aatccctaat ctgtgaaggg taggtgcgcg
    13681 gttaagcagg actggatgct ccttgataac ctcttctaga atatcccaga tacgctcatc
    13741 gccacgctca accatacgct tagctgcttt gacgttgccg gcaaattcgc gggcaacaat
    13801 ctcacgtatc acaaatggct tgaaaagctc aatagccatc tcacgtggta caccacattg
    13861 gtacattttt agcgttggac ccacagcaat aactgaacga cctgagaagt caacacgctt
    13921 cccaagcagg ttttgacgaa aacgcccttg ttttccttta agcatgtggc tcaaggattt
    13981 aagcggacga ctaccaggtc ctgtaatagg acgaccacga cgaccattat caatcaaagc
    14041 atcaaccgcc tcttgcagca tacgcttttc attttgcaca atgataccag gcgcattaag
    14101 ctccaacaaa cgtgctaaac gattattacg gttaatgaca cgacggtaaa ggtcattcaa
    14161 gtctgaggct gcaaagcggc caccgtccaa ttgcaccata ggacgaagat ctggtggaat
    14221 gaccggcaag atgttcagga tcatccattc tggcttattg cctgatttat gaaaggcatc
    14281 aagcacatct aaccgacgaa cagccttgat acgcttttgg cctgttgctg tttttaattc
    14341 ttcctttagc tcagcaattt ctgtgaccaa atcaacacgc tttaggaggt cttgaatagc
    14401 ctctgccccc attttagcaa tgaatgagcc atgtccatat tcttggattt tttcacgata
    14461 ttcacgctct gtcaatagtg attttggctc aagcggtgtg tcctttggat caataaccac
    14521 ataagccgca aaatagatta cctcctcaag agcacgagga ctcatatcaa gagtcaagcc
    14581 catacgagat gggattccct taaaatacca gatatgtgag acaggtgcct tcagctcaat
    14641 gtgtcccatg cgttcacgac gaacctttgc acgcgttacc tcgaccccac aacggtcaca
    14701 gacaatgccc ttatagcgaa tacgtttata tttgccacac gcacactccc aatccttggt
    14761 tggtccaaaa atgacttcgt caaaaagacc ctcacgttct ggttttaatg tacggtagtt
    14821 gattgtttca ggttttttaa cttcaccata ggaccatgaa cggaccttac ttggtgaagc
    14881 taatgtgatt tgcatacttt taaaacgatt tacgtcaacc actagtttta cctttctgcc
    14941 tttgatgact tactagcagc tagggcaaat agccctagtc tagtcattat ttctgttaca
    15001 aatgtttatg atttagttgt cttcagttga ttcagcaata tcttgagttt cctgagcctg
    15061 cttttcacgc gctttttcaa gatcgtcaac gtgcatcacg tcatcgtctt cgccttcatc
    15121 aagatcacga agctcaactt cattatcgtc ttcatcaagg acacgcatat caagaccaag
    15181 tgattgcaat tctttcacaa gaacgcggaa agattctggt acaccaggct ttggaattgg
    15241 cttacctttg gtaatcgcct cataagcttt caagcgacca ttcacatcgt ctgacttata
    15301 ggtcaagatt tcctgaagaa cgtttgaagc accataagcc tcaagagccc atacctccat
    15361 ctcaccaaaa cgttggccac caaactgagc tttacctcca agcggctgtt gggtaaccag
    15421 tgagtatggt cctacagaac gcgcgtgaag cttatcatca accatgtggt gaagcttaat
    15481 catatacatg acaccaactg acacacgatt atcaaacggc tcaccagtac ggccatcata
    15541 aagaacagtc ttagcatcgc tatccatacc tgcttcacga acagtttccc aaaggtcctc
    15601 agacgtagct ccgtcaaaga ccggtgttgc gatatggata cccaaattac gagcagccat
    15661 acctaggtga agctccataa cctgtccaat gttcatacga gacggcaccc caagagggtt
    15721 cagcatgatg tcaacagggg ttccgtctgg cagatatggc atatcctcaa ccggtacaat
    15781 acgtgagacg acacccttgt taccatgacg cccggccatt ttatctccga ccttgatttt
    15841 acgcttttga gcaatgtaaa cacgcaccag catattaaca cctgattgaa gctcatcacc
    15901 atttgcgcgt gtaaagatct tcacatcacg tacaatcccg tcaccaccat gaggaacacg
    15961 taacgaggta tcacgaacct cacgtgattt atcaccaaag atagcatgca ggagacgttc
    16021 ttcagcagaa aggtcttttt cacccttagg agttacctta ccaacaagaa tatcgccttc
    16081 cttgacctct gcaccgatac ggataatacc catttcatca aggtccttga gggcttcttc
    16141 accaacgttt ggcacttcac gtgtgatttc ctcaggtcca agctttgtgt cgcgtgtttc
    16201 tgattcaaac tcctccaagt gaacagaggt ataaacgtcc tccttcacaa gacgctcact
    16261 catgataacc gcgtcctcaa agttgtaccc ttcccaggtc atgtaagcaa cgattggatt
    16321 ttgaccaaga gccatctcac ctttttccat agaagggcca tcagcgataa agtcaccctt
    16381 ttcaacaata tcacctattt taacaagggt tcgttggttg taggcagtac cagagtttga
    16441 acggcggaat tttgtgatgt ggtaaacatc aagtgaaccg tcctcacgac gcacctctac
    16501 tctttcagca tctgaaaaga caaccttacc attatgctgg gcaattaccg cagcacctga
    16561 atcatgagct gcttgatatt ccatacccgt accaacataa ggagcctttg gatcaatcaa
    16621 tggcacagcc tgacgctgca tgttagctcc cattagggcg cggttggagt catcgttttc
    16681 aaggaaagga atacatgctg tcgcaacagc gactacctgc ttaggagaca cgtcaacaaa
    16741 gtcaacctga ctagcaggaa actcttggtt attaccttgg tgacgtccca tgacaatctc
    16801 ttcagcaaag gtaccgtctg gattgagctt agaattagcc tgagccactg taaactcatc
    16861 ctcttcatca gcagttagcc aaacaatctc attagtcact cggccaatca cacgatcaac
    16921 cttacggtaa ggggtttgaa taaagccgta tttgttcaga tgtccaaatg aagacaggtt
    16981 attaatcaaa ccgatatttg gcccttcagg tgtttcaatc ggacacatac gaccatagtg
    17041 agtgtagtgc acgtcacgca cctcatagcc agcacgatca cgtgtcaaac caccaggtcc
    17101 taaggcagac aaacgacgtt tgtgcgacaa ctcagacaat gggttgtgct gatccatgaa
    17161 ctgtgatagc tgtgaagaac caaagaattc tttgacagcc gccgttacag gacgaatgtt
    17221 aataatctgt tgtggagtca acacatcgtt atcctgtaca gacatacgct cgcggacatt
    17281 gcgctccata cgagcaagac caatacggaa ttggttagca agcaattcac caactgcacg
    17341 gatacgacga ttacctaagt ggtcaatgtc atcgaccttt ccaagacctt cagcaaggtt
    17401 aaggaaataa gacatctcag ccaaaatatc agccggagta agggcacgaa ccttatcatc
    17461 tgggttagca ttaccaacga tcgtcaccac acgatcagga tcaactggtg aaaccacctt
    17521 gaatttttgt aggatcacag gctctgtcac caccgcataa tcgtttggtg tgtagacaaa
    17581 cttgttcaaa tccccatcaa gctgctcttc gattgactca atcacactac gagtcatctc
    17641 tgttccagcc tcaaccagaa tctctccagt ctcactatct attagatttt cagcaataat
    17701 ttgattcaaa agacgtgtct tgatgttcag ctttttatta atcttataac ggccaactgc
    17761 tgccaagtca taacggcgag catcaaagaa acgagctgtc aaaaggctgc gtgagctatc
    17821 agctgtcttt ggctcacctg gtcttaagcg ttcataaatt tccttaagag cctcatctgt
    17881 acgtgaatcg ctttggtttt tatgaatatc cttttcaatg gtattgcgaa caagctcact
    17941 atcaccaaaa atatcaataa tttcgtcatc accagaaaaa ccaagtgcac gcactagcgt
    18001 tgtaaatggg attttacgcg tacggtcaat acgagtataa gcaatatcct ttgagtcagt
    18061 ttctagctct agccaagcac cacgattagg gataactgtt gagccataac caaccttacc
    18121 atttttatca accttgtcat tgaaataaac accaggagac cgaaccagct gagaaacaat
    18181 aatacgctct ccaccgttga tgataaaggt tcccatttca gtcataatcg gaaaatcacc
    18241 aaaaaagacc tcttgtgttt tgatttcgcc agtttcctta ttaatcaggc ggaaggtcac
    18301 aaagattggt gcagaatagc ttgcatcatg gatacgagcc tcttcaaggg tatatttagg
    18361 ctccttaaat tcgtaaccaa caaactcaag ctccatcgtg tctgtaaagt ttgagattgg
    18421 aagcacatct tcaaatactt ccttcaagcc tgaatctaag aaatcttgga atgaatcagt
    18481 ttgaatttca atcaaatttg gtaaatcaag aacctctttg attcttgaaa aactacgacg
    18541 ggtacgatgt ttcccgtatt gaacgtcatg tcctgccaag tttttagctc ctttttcttt
    18601 ttaagctttg ctatcaagca aacaattgca acatcaatat ttgtcttaag tggtattttt
    18661 agaatcttta aatttttgtt acaaaattga tttttatcta aaaataggca caaaaagagc
    18721 agctaaatcg gaccttatca gtgtgattta actgctgttc tttctagctg gacaatattt
    18781 cagctagatt agacgacaaa tagttataga tattatacac tatttgtctg gaaaatacaa
    18841 ctaatttctt ctaccactaa aacctcccca ggctttttga tagtctgcgt ctgttccacc
    18901 aatggcaaac ctataggtag ttgctccggg tcccttttga gcccaaaggc tggttgttag
    18961 ctctccaccg atggagatgg tttggccatt gatcgtcact gtacccggct ttagaccagt
    19021 ggccttcaag acagaagcct tgataacacc aggatccagt gaaaaccgct gaccaaggcc
    19081 aaaaagattg ggatcagcct gactgatggc attaaccaaa taagccatat aatttgaatt
    19141 attattgtat cccgtcagtg gtgcaagcga ggtattgtca tcatggcctg cccaaccacc
    19201 caaagtaacc cttggagtag ctaagaccag ccagacatcg gtataatttt cggttgttcc
    19261 tgttttacct atccagtcag cacctgcaag gcttgggttg atccctgcta atcggctttt
    19321 aaaagtggtt gttgccccag atgaaatcgg ccctctcaag agctcctgta aaatcgttgc
    19381 tgtcggagct gagaaaatac gaaccggctt ggcctcatgc tgataaacaa cggatccatc
    19441 actagctgtg atactagcca ccatatattg cttttgataa agaccattat tagcaatcat
    19501 ctgataagca ttggtctgct gggctaccga ggtctcaatc ccaccaccaa gtggcagact
    19561 ttcaatggaa taatcagcaa tccgatatcc cattttactc atatagtttt caacatcaac
    19621 gcccttatca cgcagcagct tttgagtcca aaaggctgga atattccatg aggtattaag
    19681 cgcctcctgc aggggcatca ttgctgttcc ttcactatcg acgtgcatga ttttttgacc
    19741 gctggaatag gtcgtcggat agttggatag gacactagca cttcccatta atccctgatc
    19801 aatggcaggt ccataagcaa taatcggctt aatgctagag cctggagagc gaacagtatt
    19861 aaaggcatga ttgttttgat tttgagcata gtctctccca ccaataaagc ccaaaacagc
    19921 acctgtagca ttgtccgtta ggacattgcc catctgcact gtcccagtgc catcatctaa
    19981 caagccacca aactgagctg ccgctttttg catcacctga tggattggct tattgattgt
    20041 tgttttgaca gtgtagccgc catgctgcag ctcagttaag gctcgctcct cataggcagc
    20101 cttagtctca tcatttttta aatctttagc aggcacctta tctcgcttaa tcagatagct
    20161 atacatggcc ttttgtgcct ctgccaagac agaatagtag aggtaatcat gagtattggc
    20221 agtgactgtt tcaggtttga taaaatcatt gctaatagga tatgccttat aatcacgata
    20281 ttctttttct gtcagcacac ctgttcgata catattgtag aggacatttt gctggcgctt
    20341 aatcccatag gccatatcat cggctgattt taactgccct gtcggcaaat acggcgaata
    20401 aacaatcggg ctttgcggaa gccctgccaa aaaggccgcc tgcggaaccg tcaaatcctt
    20461 ggcagagact ccaaaaatgc cacgcgcagc ctcctccaca cctgcaatgt tttgtccctt
    20521 attattacga ccaaaaggcg acacgtttaa ataatgtgat aaaatatcgt cctttgacat
    20581 gtaacgctct aaggccagtg catagataat ttcctttgat tttcgcctaa aggtcggatc
    20641 atcgcccaag acttgctgct taatcaactg ctgtgtcagc gtagagccac cacttgactc
    20701 cccaaagccc aaaacagagg ccagagtcgc acgaaaaatc gcctttggca caatgccatt
    20761 atggcgctga aagttgtcgt cctcagttga gacaatagcc tttttgatat tgtctgaaat
    20821 cgcatcatta gcaaccggtg tcctaagcag atccgtatca atgcctgaaa tcaagctatt
    20881 atctgaatag gtaatctgtg acatcatggt caatgattca acctgcttga caagactttc
    20941 cttacttgga atttttaccg agtcaatttg actggctaaa tagccaaagg ccataccagc
    21001 acccagcatg ccaaataaaa agacagctac ataaaaaaag ctcgacatga attttaatgt
    21061 gcgcaaaaag accgttccaa aatcaactaa ttctaatcgc tgatgatttt tgcttgtttg
    21121 attctttttc catttcacca taacgtacct caatcttcat tataccaaac tttgattaag
    21181 cttgcacagc cacagtcatt tttgatataa tgattcggaa atcataaaga aaatggagaa
    21241 agcctatgaa tatttttgaa gaactcaaag ctcgtggctt ggtctttcag acgaccgatg
    21301 aagaagccct tgtcaaagca ttaacagaag ggcaagtatc ctattacact ggctatgatc
    21361 caacagctga tagcctgcat cttggtcatc tcgttgccat tttgacatca cgtcgcttgc
    21421 agctagcagg acacaagccc tacgctcttg tcggtggggc aactgggctg attggtgatc
    21481 cgtcctttaa agacgctgag cgtatcctac aaaccaagga aaccgttctt gattggagcc
    21541 aaaagattaa agaacaactc tcttgctttc ttgactttga caacggtgaa aacaaggctg
    21601 agcttgtcaa caactatgac tggttctcac agattagctt tattgacttc cttcgtgatg
    21661 tcggcaagca cttcactatc aattacatga tgagcaagga ttcagtgaaa aaacgtatcg
    21721 aaaccggaat ttcctacacc gaatttgcat atcaggtcat gcaaggctac gatttttacg
    21781 agctaaatgc taagcacaat gtgacactgc aaatcggcgg ctctgaccag tggggtaata
    21841 tgacagcagg taccgaattg ctccgcaaaa aagctgacaa gactggacat gtgatgacag
    21901 tgccattgat tacagatgca acaggtaaaa aattcggcaa gtcagagggt aatgcgattt
    21961 ggcttgacgc taaaaaaaca tctccttacg agatgtacca gttctggtta aatgttatgg
    22021 acgatgatgc ggtacgcttc ctgaagatct tcaccttctt atcacttgat gagattgctg
    22081 ctattgagga gcagttcaac gcagcacgcc atgagcgcct tgctcaaaag acacttgcgc
    22141 gtgaggtggt gacactggtt catggagagg cagcctacca gcaagccctc aatattaccg
    22201 aacagctttt tgcaggagct atcaaaaacc tttcagcagc tgagcttaag caaggcttaa
    22261 gcaatgtccc taactatcag gttcaagcag aagacagcct aaatatcgtg gatatgttag
    22321 tcacagcagg catttcacca tcaaaacgtc aggcgcgtga ggatttacaa aatggcgcga
    22381 tctacctcaa tggagaacga cttcaggatc tggattacag cttatctaca gcagatcgca
    22441 ttgacaatca gttgaccgtc attcgccgcg gcaagaaaaa atacgctgta ctaacctact
    22501 aatcacagac agctaggaaa atcttgcttt ggatgattat ttttgacgta taaaggacag
    22561 caggttaacc acaaggaaga tcgcaataaa aatcatcgta atggtcgcac ttgccggcgt
    22621 ttcccaaaaa taggacaaga aaataccaga cagcatgcct gtaaagccaa tcataatccc
    22681 aagaaaaata actgatttaa agtttttccc aagccgcata gcaatacttg ctggcaaaac
    22741 cataatcgtt gataccaaaa gggcccctgc cgctgggatc gttagagcaa tagcaacacc
    22801 tgtcacaata ttaaacaaga cagacatgac acgcaccggc aagccatcga cgtaggctgt
    22861 gtcctcatcg aaggtcaaga tatacattgg acgaataaat aatatcgtca aggctaaaat
    22921 aatcaaagca atgacaaata aggcagcaac ctgctccgta ctaatagtaa tgatagagcc
    22981 aaaaaggtat tgctccaagc tcatactaga agagctagtt gacttactca tgataatcaa
    23041 ggaaatagcc agccccaagg acattaggat agctgtcgaa atctccatat agtgcttata
    23101 aaccacccta agatattcta gcaagatggc agctagcacc accacaataa tcgttgtgaa
    23161 ggttggcgaa acaccaagaa caacaccaaa ggccacacca gccagagaaa cgtggctaag
    23221 cgtatcactc aacaagcttt gacgacgcaa aatcaaaaag atacccaaaa tcggagcaaa
    23281 gatactgatc gccacaacag ccataacagc acgctgcata aaatcataag ataaaatctc
    23341 aagcatggaa tgaccctcct ttgctctcat cagcctcagc atcatgaatg ttgaagcaac
    23401 gccaaggaag ccgttgattt ctaatcaaat gaatattgcg atcagcataa gccttgacct
    23461 cctctgggtc atgtgtaatc atcaaaacag ccttaccatg tctatgagcg ctgtggtgca
    23521 tcaactcata aaaagtatct gttgttccac tatccattcc tgtggtcggc tcatcaagca
    23581 caaaaatatc ggggtcagaa gcaaacatac gcgcaataac cacacgctgc ttttgaccac
    23641 ctgatagact ccctattctc ttatgccgac tatcccacat gccaacagac tccaagcttg
    23701 tccgaacatg ctcctcatcg tgcttactta gtctggtaaa ccaaccactt ctaggatatc
    23761 tgcctgattt aacaaattca taaacagtcg acggaaagcc tgcattaaag ctggcaacct
    23821 gctgtggcaa gtaagcaatt ctcagctttt tcccatgaat gttctgttta gctatagtca
    23881 cctgcccagc ccttgacttt aaaatcccca aggtcgcctt gatcagggtt gacttggcag
    23941 caccattttc accagtcaat gtgacaaatt ctccactatc caaatgatag ctgattccct
    24001 ctaaaacagg ctcactgtca tactggaacg agagattttc caccgatatg tatctcatta
    24061 ttacccttct aactcctccg caaaagcagt gataaatttt tcaacaatca cctgctcctc
    24121 cgcagaaaaa tgtgccaaca aacgatgata aacagctagt gttttatcgt gatgatgtgt
    24181 atgctcctta gcgattggcc ttgctagatc agtcagttca aaataggtta ctcgagcatc
    24241 aacggtatcc tttgttcctg ctagcatttc ttgcttgatc aagcctttaa tcgctttagt
    24301 tactgctgct tgactgatat ttagcctttt tgccaaatct gtattggtta gcttttcctg
    24361 tgacaaaagc atcaaaatat gctcctgagt atttgttaat ttgacatcac tctgacaagc
    24421 cccaaagagc agctcatgct gattttcagc ctttaacaaa atacgattaa ccaaattatc
    24481 aagctttttt tctaaaattg tcatgatttc cctctcctca ttaaccagtt aattataaca
    24541 tgacgcccca aaagacgcaa cttcaaggct gatctacagc gttctaacct tgtagacttc
    24601 cttacaaaag cctttcaggc tattcaccac acgattggcc tgcttttctg tttgacatag
    24661 ggcaaatacc gttggaccac ttcctgtcat cagggcaatg tctgctcctg actgcagcat
    24721 tttatcctta accttttgaa taaacggccg tttagcaatg gaaatatcct ctaaggaatt
    24781 tcccatcgtt gcaagcaagc gctgataatc acctgcctca atggctgaaa ccagatcctc
    24841 aatcggcact cgagatatcg tctcacaatc aatatcccaa aaaatcgttc tagtagaaat
    24901 gccaaattct ggcttcacta gaaccaccca agaggacaag cggccattga ttggcttaac
    24961 cacctcgcct ttgccagtca cttgggcgca gcctgcaaaa agacaataag gcacatcgct
    25021 accaatctgc atgccaatgt caatcatctg acggggacta agctttagct gccacagctg
    25081 attcaatgct ctgattgctg cagccgcatc acttgagcca cctcccatac cagcacaaac
    25141 aggtaccctc ttatccaaga aaatagagac acctgttgag atttgaaatc gctctttcag
    25201 caaataagcc gccttgtaaa cgtcattgtg ctcattaata ggcaatctag ggcaattaga
    25261 ggtcaataaa atcctatcct cctctaaatg atccactgta atataatcac aaagatctac
    25321 actaactaga accatagata ggtcatgata gccatctggt cgcttgcctt gaatatctaa
    25381 gcctagattt atttttgcag gagctctctc aatgattgca gtcataatac tcctttattt
    25441 gatgtcatta tagtatcaaa tatacacaat cttcatgaaa aattcaaata aatacagtta
    25501 gtatctaatg atgcatagac agcgtgtttg tatcaaaaca gccaaccatt tgtccctact
    25561 agcgtgaggc ttcaccagat cagcagccaa aaaacgacaa ctactagcat agcaagcaaa
    25621 gctaagacag cagcagtctc tatgaccact tgatcgctcc atattgcccc actaactcaa
    25681 agcacatatc aatcttgctc ttaaagtagg gaataaaaat accagcatca atcatggcta
    25741 aaatctcatc acgactagcc catcgaacag cctgtacctc ctctgtctga agaactagct
    25801 tccttacatc aacagcctgc aaaatcaaaa aagtatcgtc aaagccatta tcaaaggtaa
    25861 ttgaaaaatg aggccttaca ccagctaaat caagagtaag tcctagctcc tccttcagtt
    25921 ctctcatcac tgcctcttgt gacgtctcac ctgcaagagc gctgccgcct accgttatat
    25981 cccaatagct gggccaaccc tctttatcct tttgccgctg ctgaatcagc atttctccct
    26041 tgtcattaaa gacacaggcg tgaaccacta aatgataagc accctctaca aaagcagctc
    26101 cacgctccat gagtctacca gtcttaagac gattcatcgt ataaatgtcc caatactcaa
    26161 ccatacaaac acacctcctg atacagctat taccagatcc agtatattaa tcatatcaca
    26221 ataagcatat ccaaaacaac caggtccaga caaaacaaca attaccaacc tagcttaatt
    26281 cttttttcta caattcccta ccttaaaatg cctcgcatag aaaatggaca aaaagatctg
    26341 ttttcccgag acgtatcaaa aagctcacca cgctaacaaa ctggtagtta agatccccaa
    26401 gcgtcttact cagttaacga tatggtgata cacacagctg acttgcctca tcatattagt
    26461 tacaaaaaac cttaaaggct caacccaaaa gcacaccaac tacatcaccc catgaaagag
    26521 gaagacaaaa catctactgc tgcaagcaaa aagagacccc attagggcct ctctagtgct
    26581 catatcagct tttaaactaa tcaatcgcct tcaagctaaa ggctatcatt tagtaggaga
    26641 aagttgcaaa agctaattta gttgtttttt ctttttagag ttagcaggcc tgcgctggca
    26701 atgacgccga gagctgcaag ggtgaagaat gggtgatttg tctctcctgt agctggtaat
    26761 ataccctttt gagctgctgg agccgctgat ttgcttggtg ctgacttagg cgctggtacc
    26821 ttaggactag ctgactgctg ctctgaagtc tttggtacct gtggagcagg agattgctcc
    26881 ggggcctttg gagctgatgg tttggtatcc tttccttgct cgcccttttc accgcgttgg
    26941 ctttgttcac ctttttcacc gcgttggcct tgttcacctt tttcgccacg ttggccttgc
    27001 tcgccttttt cgccacgttg gccttgctcg cccttttcac cgcgttggcc ttgttcacct
    27061 ttttcgccac gttggccttg ctcgcccttt tcgccacgtt ggccttgctc gcctttttcg
    27121 ccacgctggc cttgctcgcc cttttcaccg cgttggcctt gttcaccttt ttcgccacgt
    27181 tggccttgtt cacctttttc gccacgttgg ccttgctcgc ccttttcacc gcgttggcct
    27241 tgttcacctt tttcgccacg ttggccttgc tcgccctttt cgccacgctg gccttgctcg
    27301 cctttttcgc cgcgttcgcc tctgtcaccc ttagggccac gctctcctgg cttaccagta
    27361 ggaccggtcg gaccttgttc tcccctaggt ccaatttctc cagtttcacc cttgtcacca
    27421 cgaggccctt ggggtccaat aggccccgct gggccttgct cacctctttg gccctcagga
    27481 cctcggtctc ctttaggtcc tggttctccg cgttcacctc taggaccagc aggtcccaca
    27541 ggtccttgtg gccctccttt ttgagcttct tcttctaaac ttcctaaata aggtttcaaa
    27601 aactcatata attgattaag atactttcta gcttctctat cagtagttct tgttgaatta
    27661 tattgaataa tttctactgg at
//
LOCUS       DARYUW010000029        26831 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYUW010000029 DARYUW010000000
VERSION     DARYUW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26831
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            57..332
                     /locus_tag="TVW11_001098"
     CDS             57..332
                     /locus_tag="TVW11_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1365201.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
     gene            329..1651
                     /locus_tag="TVW11_001099"
     CDS             329..1651
                     /locus_tag="TVW11_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1365202.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWSTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICISMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKTTVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1652..1840
                     /locus_tag="TVW11_001100"
     CDS             1652..1840
                     /locus_tag="TVW11_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365203.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREMKNEQTKI"
     gene            1821..2048
                     /locus_tag="TVW11_001101"
     CDS             1821..2048
                     /locus_tag="TVW11_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365204.1"
                     /translation="MNKQKFEKLDKVKELLDELKMSEFMAPLLVGDQIMEIINDLHND
                     PGQFGAQVFLPSPDKKYKFVVRICREENLED"
     gene            2073..2258
                     /locus_tag="TVW11_001102"
     CDS             2073..2258
                     /locus_tag="TVW11_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365205.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFNRGTK"
     gene            2255..2548
                     /locus_tag="TVW11_001103"
     CDS             2255..2548
                     /locus_tag="TVW11_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365206.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            2545..3261
                     /locus_tag="TVW11_001104"
     CDS             2545..3261
                     /locus_tag="TVW11_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1365207.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVLQYVADWYEKHKDNLEYYIWEYIAEWDNQEKDDFFVFMNFSAFKPIQTL
                     VNMHQFGYTIKKEKLYTVEIPNPNAKQIALRLEKWVEGKVRIVATYSSNNFTDYMRLT
                     EREIRKDFDWAWQFAEEVTG"
     gene            3258..3674
                     /locus_tag="TVW11_001105"
     CDS             3258..3674
                     /locus_tag="TVW11_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1365208.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            3764..4216
                     /locus_tag="TVW11_001106"
     CDS             3764..4216
                     /locus_tag="TVW11_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1365209.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            4206..5483
                     /locus_tag="TVW11_001107"
     CDS             4206..5483
                     /locus_tag="TVW11_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1365210.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            5499..7031
                     /locus_tag="TVW11_001108"
     CDS             5499..7031
                     /locus_tag="TVW11_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1365211.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            6991..8439
                     /locus_tag="TVW11_001109"
     CDS             6991..8439
                     /locus_tag="TVW11_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1365212.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            8467..8655
                     /locus_tag="TVW11_001110"
     CDS             8467..8655
                     /locus_tag="TVW11_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365213.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            8660..8917
                     /locus_tag="TVW11_001111"
     CDS             8660..8917
                     /locus_tag="TVW11_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365214.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            9094..9663
                     /locus_tag="TVW11_001112"
     CDS             9094..9663
                     /locus_tag="TVW11_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1365215.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            9676..10563
                     /locus_tag="TVW11_001113"
     CDS             9676..10563
                     /locus_tag="TVW11_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1365216.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            10575..10931
                     /locus_tag="TVW11_001114"
     CDS             10575..10931
                     /locus_tag="TVW11_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1365217.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            10942..11220
                     /locus_tag="TVW11_001115"
     CDS             10942..11220
                     /locus_tag="TVW11_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365218.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            11217..11561
                     /locus_tag="TVW11_001116"
     CDS             11217..11561
                     /locus_tag="TVW11_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1365219.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            11565..11924
                     /locus_tag="TVW11_001117"
     CDS             11565..11924
                     /locus_tag="TVW11_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365220.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            11936..12535
                     /locus_tag="TVW11_001118"
     CDS             11936..12535
                     /locus_tag="TVW11_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1365221.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            12589..13044
                     /locus_tag="TVW11_001119"
     CDS             12589..13044
                     /locus_tag="TVW11_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365222.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            13119..13352
                     /locus_tag="TVW11_001120"
     CDS             13119..13352
                     /locus_tag="TVW11_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365223.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            13367..17749
                     /locus_tag="TVW11_001121"
     CDS             13367..17749
                     /locus_tag="TVW11_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1365224.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNTFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSVLSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            17761..18603
                     /locus_tag="TVW11_001122"
     CDS             17761..18603
                     /locus_tag="TVW11_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365225.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            18613..20595
                     /locus_tag="TVW11_001123"
     CDS             18613..20595
                     /locus_tag="TVW11_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365226.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            20595..21713
                     /locus_tag="TVW11_001124"
     CDS             20595..21713
                     /locus_tag="TVW11_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1365227.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            21728..23614
                     /locus_tag="TVW11_001125"
     CDS             21728..23614
                     /locus_tag="TVW11_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1365228.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            23626..24063
                     /locus_tag="TVW11_001126"
     CDS             23626..24063
                     /locus_tag="TVW11_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1365229.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            24060..24671
                     /locus_tag="TVW11_001127"
     CDS             24060..24671
                     /locus_tag="TVW11_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1365230.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            24683..24955
                     /locus_tag="TVW11_001128"
     CDS             24683..24955
                     /locus_tag="TVW11_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365231.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            24952..25179
                     /locus_tag="TVW11_001129"
     CDS             24952..25179
                     /locus_tag="TVW11_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1365232.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            25296..26630
                     /locus_tag="TVW11_001130"
     CDS             25296..26630
                     /locus_tag="TVW11_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1365233.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
BASE COUNT         8992 a         4675 c         5995 g         7169 t
ORIGIN      
        1 agaaaataag ttgaaaaaaa cggtaaccct gacctttatt gaccaaagga ggaaagatga
       61 ggactgaaaa agacattgaa aattatttga aaaagaaaac aaaagggctg tgtttaaaat
      121 ttgcaagtcc agggacgata ggagtgcctg acagaattgt tgtcatgaac acgggaacct
      181 tttttgtaga ggtcaaagca cctggtaaaa aaccaagacc cagccaagtt gccatgcaca
      241 aaaaaataaa agaggctggg cagcacgttt gggttgttga ctcctacgaa tcagtggaca
      301 tagccttaaa agaaatggag aactgggtgt gagactgcac gagtaccaag aatacgctaa
      361 gacatggata gtagagcacc cttattgtgg ccttttactt gacatgggtc ttggtaaaac
      421 gctgacaaca ctatcggcaa tagatgagat tcaaaatatt ttttccgagg atcataagat
      481 tttaatcgta gcccctaaaa aagtggcgga agaaacgtgg tcaacggaga ttgggaaatg
      541 gcattttgat ttcacctact ctaaagtttt agggagtgag ggaaaacgaa ttgaagcctt
      601 agaaacagaa gccgatatct atttgattaa tcgtgagaat gttacttggc ttgttgaata
      661 ctacaagact aaatggccgt ttacctttgt ggttattgat gagctgtcaa gctttaagtc
      721 tagtaagtca aaacggttta gggctttgcg aaaagttaga ccgaaagtcc aacgccttgt
      781 aggactaaca ggaaccccag cgcctaacag tttgattgat ttgtggccgc agatttatct
      841 gatggacaga ggcgccaggc ttgagacgag ccagactcga tttaaagaca agtattttgt
      901 tcctgataag cgtaatggcc taatcattta cagttgggca cttagggatg gtgcagaagc
      961 agaaatctat aacaagattg aggacatctg tatcagcatg aaagctaaag actatctcaa
     1021 gttaccgccg cgaaccgaca acgttgtatc agttaagtta tctaatatga aagcctacaa
     1081 acagcttgaa gctgatttgg tgttggagtt taaggataag gagatatctg cggctaactc
     1141 tgcggttttg gctaataaat tacttcaaat ggctaatggc gctatctatg atgatgataa
     1201 aacaacagtt gctatacacg acgacaaact tgacgcgctt gagaatgtcg ttgaagaaag
     1261 ccaaggccag ccaatcttag ttttttacca gtatcaacat gatcttgaaa ggcttaagaa
     1321 acgattccct caggctgaag agttgacgtc agttgacaag tggaattccg gaaaaatacc
     1381 aattcttctg tgtcacccac agtcagccgg gcatgggctt aatctgcaaa aaggagggca
     1441 tattattgtt tggtttgggc taacatggag tcttgaatat tatcaacaag ctaatgccag
     1501 attagacaga caagggcaga cagaacccgt tattgtgcac cacattgttg cagaaaatac
     1561 agttgatgaa aaagtactta ggattttaca aggcaaagaa aaaaatcaga acgccttact
     1621 tgaagcagtt aaggcgcagt taggggtcta gatgaaaaaa gaatatgtcg ttagaatcta
     1681 cacgggtaga gaaaagaatt ttgaggcaaa acctcagttt gaagagaaaa cctttacgcg
     1741 aaaagcagac atgctgaggt tttgggattc ttgcgaagca acagttaaag aaaaatatac
     1801 tagggagcgg gagatgaaaa atgaacaaac aaaaatttga aaaattagac aaagtaaaag
     1861 aactacttga cgaattgaaa atgtcagaat ttatggcgcc acttttagtt ggtgatcaga
     1921 ttatggaaat tatcaacgat ttgcacaatg atccaggaca atttggagcg caggtatttc
     1981 tgccatcgcc agacaaaaaa tataagtttg tagtgcgaat ttgtcgagaa gaaaatttag
     2041 aggattgagt taacgaaaat gagggtagga taatggctga aaataaaact ggaatgatga
     2101 ctttaccaat cgactatgca aacagagcat tagcaaaaga ggaaatactt gatgaacttg
     2161 ttgaaagaga aattgtagat gtagatctgt taatagagct tgcagaagat aatccgtttt
     2221 ggatgagtgc attgaatttt aaccgaggta caaaatgaac actaacgaaa aagtaatcga
     2281 tactatatgt cacatcagac attgcggtga cagatacgat atgtgccaag acatgcggtc
     2341 gtgggtagct gagagaaatg gattaatcca ggacttactc aaagcaaaaa aacaaattga
     2401 tcgcaatcgt atcgctaaac gtctggatcg tgcgcagaaa aacatcagtg acattatcac
     2461 aaaagtgaca ggcgacttat ggcaaggcag tgatcaagtc attgctgagc agtgtttttt
     2521 aaaagtatta gaggagatgc aaaaatgaac attaaagaag cgaaaatagg cgataaagtg
     2581 tgggttgaag gtattatcaa ttcgtccttt tcaaatggtg gagtacatgt aaatcatgct
     2641 ggtgttgacg ccttttatga tcttgagcga acaaaaataa aaccagacgg atacgcaggg
     2701 cagtcaccta aatatcttaa aaatattatt gctaaaatgc gagaactacc agagcacgac
     2761 agagccgtct ggattaaagg tatttttaag gaatttggta ttgagaacga cattagctat
     2821 tatcttggcc acaagcaagg cgtattacaa gcaaaggatt cgctaaaacc agaagtactg
     2881 cagtatgtgg cggattggta tgagaaacat aaagataatt tggaatatta catttgggaa
     2941 tatatagccg aatgggacaa tcaagaaaaa gatgattttt tcgtttttat gaattttagc
     3001 gcatttaagc ctatccagac gttagttaac atgcatcaat tcggatacac aatcaaaaaa
     3061 gaaaagctgt atacggtgga gatacctaat ccgaatgcta agcaaatagc tttgagactt
     3121 gaaaaatggg ttgaaggaaa agtaagaatt gttgcaactt actcatctaa taattttaca
     3181 gattacatgc gcttaacgga acgagaaatc cgaaaagatt ttgattgggc gtggcagttt
     3241 gcggaagagg taacgggatg agtagattat ctaatgcaca gctaaaggct tttgatgaat
     3301 ggttgtttga ttatcgtttt attgataaca agattgcact tcgaaaactt gagctacaaa
     3361 ctgacatgaa tacagaagta gataaaaata tcggtggagg aagagcaaat tttgtttcaa
     3421 aagttactga ggatgtggtt gcaaggtggg attcagatag ggaactaaag ggtctatcca
     3481 atttcaaaga agcagttatt gcaacgctaa atcttttgga tgaagaacta actgatattt
     3541 ttaatcttag gtggggcgtc ggttcaagta acacttggga agaaattgcc tatacaagac
     3601 atctgtcgcg taagtctatt taccgcaaaa gagagcggat tctagaaata ttttccaaaa
     3661 aaataggaat gtgacacaaa aatgtatgga attgtcatct ttttgatgat aaattggtag
     3721 tatgagtttg aaggtaaggc agatagtgtc ttgccttttt gctatgcttg gaggtgatgg
     3781 aaaattgagt aaattaaccc taaaacagaa gcgttttgca gatgagtaca tcatctcagc
     3841 taacgcgaca gcagcggcta ttaaagcagg gtatagtaaa aagacagcaa ggtcaatagg
     3901 tcaagaaaac ttgaccaaac ctgacattaa agcttatata gacgagcggc ttgaaaaact
     3961 tgaatctgaa aagattgcta cgcaagaaga agtcctacaa tatctcactt caattatgcg
     4021 aggagaccaa caagaaaaga cgctcattag cgttggagag tttggtcaga agatagttga
     4081 catcgatgtt ggtgccaagg atagaatcaa ggcagctgag ctactaggca aacggtacag
     4141 gttatttact gacaaggttg aaatggatgt cagctcagat gtaaccatta acgtaggtga
     4201 gtgggatgac gactaaacag cgccctaaaa ttaatatcgt gatcaagcat cctagcaaag
     4261 tttttaacaa acatatctac gacaaacttt acaactatag caacttcacg gaagttcatt
     4321 atggtggggc gtctagcgga aagtctcacg gtgtttttca aaagataatt ttaaaagcac
     4381 ttaaccctaa attcaaacat cccagaaaga tattagttct cagaaaagtc ggtgcaactg
     4441 ttagagactc tgtatttgct gatatcatgt ctaatttgtc gtatttcggc atcttggata
     4501 aatgtaagat aaatatgtcg gcttttagaa taacgctccc aaatggcgca gaattcattt
     4561 tcaagggtat ggacaaccca gagaagatta agtcaattaa gggtatatct gatgtggtta
     4621 tggaagaagc tagtgagttt acgcttgatg attatacgca gttgaccttg cgtttaagag
     4681 ataagaaaca tctagagaag caaatatact tgatgtttaa cccggtatca aaagtaaact
     4741 gggtttataa agccttcttc gttaagacac ctaagaatac agttgtctat caaacaactt
     4801 ataaagacaa ccgcttctta gatgatgtca cgagagaaaa tatcgaggaa ctagccaata
     4861 ggaatgaagc ttattacaaa atatatgctc ttggccagtt tgctacactt gataaactaa
     4921 tttttcccaa atatgacaag caaatattaa acaaagacaa gttatcacac ttgccttctt
     4981 tttttggttt ggactatgga tttatcaatg atccttcggc acttttgcat gttaaaatcg
     5041 atgacgcaaa caagaagtta tacatcttag aggaatatgt caggaagaat ttgaccaatg
     5101 acaaaatagc aaatgctata aaggacctcg gctacgccaa agaagaaatc agaggagatt
     5161 cggctgaaaa gaaatctaat caagagctga ggaatttagg tattcctaga atgattgatg
     5221 ttaccaaagg gcctggaacc gttatgcaag gaatacagta tttgcttcaa tatgattgga
     5281 ttgttgatga aaggtgtgtc aagactattg aagaactcga aaattacact tggaagaaag
     5341 acaagaagac taatgagtat accaacgaac cagttgacag ctataaccac tgcattgatg
     5401 ccataagata tgccgtacaa gacagaatat accagtcggc ggatagaagt aagcgcatga
     5461 aaaatgctaa atattatttt taggaatgag gtgaaacttt ggaagaaaaa caatttttag
     5521 caggaactcg ttttaatgag aatgctaata agcaatttat tatgctgcaa gaagactttg
     5581 aagcaattga ctatgaatca aaactttgga tagatcaact taagaattac atttcaaggt
     5641 ttaaagcaga acaattagag cgtttgaaag agttaaagcg atactatctt ggggataata
     5701 acatcaagta tagacctgct aaaacagata aatacgcagc ggataatcgt attgcaagtg
     5761 attttgctaa gtatattacg gtatttgagc aaggttatat gcttggcgtt cccgttgagt
     5821 acaaaaatga aaataaagac ctccaggcag ctattgacct tatgtcggtc agaaacaatg
     5881 aggactacca caacgtcaaa ataaaaacag atttatcaat ttatggaaga gcctacgagc
     5941 tgttaactgt tgagaaaata gatgacaaaa aaaccgaagt aaaactctac cagctcccgg
     6001 ccgagcaaac ttttgttatc tatgatgata cataccagcg aaattcgttg atggccgttc
     6061 atttctacga catagattac ggctcaggta aacgtaaaca gattatcaaa gcatatactt
     6121 ccgacacaat ttatacctac gaagactata accttgaaac aaaaggtatg cgattaaaag
     6181 attatgaagg acattttttt agaggtgtac cagtcaacga atacgctaat aacgaggagc
     6241 gaacgggggc ttatgagtct gtacttgata atattgacgc ctatgattta tctcaatcag
     6301 agcttgctaa ctttcaacaa gattcagtca atgcgttgct tgtaatagct ggtaatgctt
     6361 acacaggagc tgatgagaat gactacttag atgatggccg attaaatcct aatggtcgtt
     6421 tagcgatctc aattgggttt aaaaaagccc aagtgttaat tttagacgat aatcctaatc
     6481 caaatggcgt taaaccgcaa gcgtactttc tcaaaaaaga gtatgatacc gccggtagcg
     6541 aagcctacaa aaatagatta gttgcagaca ttttgaggtt tacttttacg ccagatacac
     6601 aagatatgaa attttcagga gttcaatctg gtgaatcaat gaagtataag cttatggctt
     6661 ctgacaacta tcgcgagaag caagagaggt tgtttaaaaa aggattaatg cgacgcttac
     6721 gcttagcagc taatatctgg gccatcaaag ggaatgaagc aactacatat agccttgtaa
     6781 atgatacgag tatagttttc acacctaatc ttcctcaaaa cgataatgaa attgttacag
     6841 ctgcacaaaa tctttatggc attgttagcg atcagactat ctttgaaatc ttaaatactg
     6901 tcacaggagt agatgctgaa gcagagcttg aacgcttgaa agaagaagct gataaaaagc
     6961 aatctttacc ggagcctaga ttggtaggtg atgctagtgg tcaagaagaa ccaacggcag
     7021 aaaagcctta attactggca aaagcgtcaa aaagatattc taagttattt agacagaact
     7081 gatttagatg tcttttcaga actgcagaag ttatataatg aacaggcttt tgagttacaa
     7141 aaggaattgt ttgattttta tactaagtat tctgaagaga acaaaatgac ttatcaggat
     7201 gtcgttaaaa aactacgtca tgaagattta tcagattacg tagctaatgc taacaagtat
     7261 cgtaaacaag ctgagaaaga tcctgagctg ctaaaacgac ttaatgagca gtatgtatca
     7321 gcaagagcta caaggatgga tgcattaaat cttgagcttg tttatcgtgc ggggatacta
     7381 aaaggtgtac ttgattcagc atttgaaaat catttaaaaa aagttgcctc atatgcttat
     7441 aaaaaagcaa tgggtggacg gtcagggaca atcaatggtc cagttttaga agaactggtt
     7501 agaaccccgt ttgatggtta taactattca gaacagttgt ggggcaatac tgacaatctt
     7561 gttaagaatc ttcaaaagag attaaaacaa ggttttgttc gtggcgagca tcctagagcg
     7621 atggccagag atttagctaa gcgatttaat gttgctaatc acagggctga aacactaatc
     7681 agaactgatg gaactatggt gattaataat gctaccgcta ggcgctactt gaatgcagga
     7741 cttaagtatt atcgtgattt agttagactt gatgacagga caactgagat atgccgtaca
     7801 attgctaaag aaaacaaaag aaagctatta tctgagctaa agcctggaat taatgtagca
     7861 ccctatcatt tcaactgcag aacaactatt attcctgatg aagatgagct aagtattgaa
     7921 gtagaaccaa ttgatgataa aagcactaag tattttaagg atgtcacctc agattggata
     7981 gatggaaatg agcataaacc acaactgtca ctactaaatg agtacgtaaa aaatggcact
     8041 ccttacaaag tagatggcca tagtgtcgtt cttgatcatt cgaattatga atatagagtt
     8101 gctaattggt tatccaaaaa gacaggattg caagttgaca tggtgccaag agttaattcc
     8161 cctgaacata tcaagactcc tgattattta gttgatggag ctccttttga tctaaaagaa
     8221 atcacaggtt cgggtaaaaa cgtcattgat ggcaatctac gaaaagcaaa aaagcaggca
     8281 actaatatca tttttgatat aacaaaaacc cctttatcat ttgaagagat aatggggcaa
     8341 ttagaacata tttatatgat agatcgtagg ggtcttgata tatcaattat caaaaataaa
     8401 gatgaggtat tagctgtatt agaaaaagaa ggaggatgac ccaccgcctc cacagtaaac
     8461 tgcttcatgg gcgttagacc atcatccttc tttatctcaa ttatacatca ccctattaaa
     8521 actatcaagg aggaaaatat gtttatttgg caaatggtat tagtggcact aggtgtattg
     8581 gtactcatat tgattgttgg cattgcagca atagcggtta agtcaattat tgcagaattg
     8641 aaaaaagaag gataaaacaa tgaataagcg cattaagaaa aaacgtaaat tggaaacagc
     8701 ggttgtgatg cttgttgcag agaatgccat gcaagcagaa gctattaaaa atcaaaacaa
     8761 acaaatcatg gagctaaaat caatcgttca acgaaacgct ctggcaacaa acgaagagtt
     8821 agcgactgtt aaagctgcta ctttagataa ccaatcagtt atcaaggcaa ttggtgacac
     8881 ggttgactat attaagaaaa actacaaacg gaagtagggg aaataaagtt taaccgtgtc
     8941 gaatttgacc tctttacaaa tctaaaccaa agtcgtagca atacggcttt ttattgtgtc
     9001 caaactttgt tgatgacact aaaagctaca ctgtttcgtc gcaggacgta aagctagact
     9061 atcggttggt ggcgtaacca ctaggagaaa gttatggcag aagaaaatgt aacaacagag
     9121 acaactgagc aagtcgacac tcaaaaagaa gctgttgaac atcctaagca tgaatatgag
     9181 cgaactttta ctcgcgcaga catctcaaaa atgatggctg ctgaacgcac taaatgggaa
     9241 tctgaacaat ccgcagctat tgaaaaagct cgtacagaag gtgaacgttt ggccaagttg
     9301 tcaaaagatg agcgcgctaa agaggaggaa caaaaacgtc tagatgctat cgcagagcgt
     9361 gaaaaagcag tagcagagcg tgagatgcgc attgagacgc attccctgct tgtggagaaa
     9421 ggattgccat tggattttat tgatattgtt ttagccacta ctgcagaaga ggttaaggcc
     9481 aatattgata atttacaaac tatttttgat aaagctgttg aaaaacgtgt taacgatcgt
     9541 ttaactcaga aaccgccacg aactggaaat ggctcggtcg gtatgactaa ggctgacatc
     9601 atggcgatag aggatgacga cgaacgtatg cgtttaattg ctgagaatcg taacttattt
     9661 taagagggga atattatggc tgaaaaaaac ttaaacacta tggcggactt aggagatatt
     9721 aaatcaattg attttgttaa caagttttcc aaaaatatta atgatttact aaaattgcta
     9781 ggggttactc gtcgtgaaac attaactaac gatctaaaaa ttcagaccta taagtgggaa
     9841 gtgactttag atcaaactga tcctggagaa ggggaaacaa tccctctgtc taaggttact
     9901 cgaactaaag ataaagacta tacagtgaag tggttcaaga aacgtcgtgc aactacagct
     9961 gaggcaattg ctcgccatgg tgcagctcgt gctattactg aagcagataa gcgcattatg
    10021 cgtgagcttc agaatggaat taaggatgca ttctttacat tcctcaaaac aaaaccaaca
    10081 aaagttaaag gcgttggcct tcaaaaagcg ctgtctgcat catgggctaa gctagctact
    10141 tttaatgagt ttgagggttc cccgcttgtt tcttttgtct ctcctttaga cgtagctaac
    10201 tatcttggag atactaaagt aggtgcggat gcctctaatg tttttggaat gacattgctt
    10261 aagaactttt tgggtatgca aaatgtgatt gttatgccat ctgtgccaga gggtaaaatc
    10321 tactcaacgg ctgtagaaaa tctagttttt gcatctttaa atgttaaagg gggagacttg
    10381 ggcggcttgt ttgctgattt tactgatgag acaggtttaa ttgctgcagc tcgtaatcgt
    10441 cagctttcta atcttaccta tgaatctgtt ttctttgggg cgaatgtact gtttgctgaa
    10501 attcctgaag gggttgtaga ggcaacaatc gaagctgctg ctgtacccgg cattggtggt
    10561 taaaggctat ttatatgggt gataaacaac ttattgacga tatcaaactc tttataggta
    10621 tttccaaggg tgatggtgcg caagatgagc tcatcaccct tgctatatat gaaagtaaag
    10681 agcgtgtgct agctaaactt aatgaatact cagaaactga aatcaccaaa attcctgata
    10741 gattgaggtt tattgtccgt gatgttgcta ttaaacggtt taataggatt aattcagaag
    10801 gagccgttga agatagcgaa gaaggaaaga cttttaagtg ggacagttac cttaaagagt
    10861 atgaatcaac actcagaagc gctgctattg ggaaggtata ttcaggcaaa ggggtagcaa
    10921 gatttattta ggagatacac aatgatctat aaagatagag taatcttagt gtatgtcgat
    10981 gaacaggacg attttctaga taaaagaact gttgaaaaac ctagcgggaa aatcccctgt
    11041 atggaaaata ctttcacaaa atctgaacag atggggctat ttggtaaata tgatttgaat
    11101 gcttttaagt tgcacttgca aggccattac gacggcttta gcaagattat ctacaaggga
    11161 aaatcgaggt tgataaaggg actagcacac cataaaaata gcacggttat ttatgtatga
    11221 gtcttattta tcggatgaga ggcctagata ggtttttacg cagcgttgag cgcaagcaga
    11281 agtcagtacg aatcgctgta gataaagagc ttagtaaatc agctgctagg attgagagac
    11341 aggctaaaat actagccccg gttgacactg gatggctgag agctcaaatc tacagtgagc
    11401 aacaacgact cttacactat agagtggttt ctcctgcttt atattctatt tatcttgaat
    11461 taggtactcg taaaatggaa gcacaatcgt ttttagaccc tgccctgaga aaagaatggc
    11521 ctgtgctaat ggctaatatc aaaaaaatgt ttaagaggtg atgcatggat tactcactgg
    11581 aaacactata tttaaaaaag gtaaaaaata gattgggagt tttagacata ccaatctatt
    11641 ttaaattgcc taaatcagac gttttagagc cttttattgt tgtaggtaca aatatatcag
    11701 acttgtcaaa aacagctcaa actggagcag ttattgatga ttttagcctg aatatcgatg
    11761 ctttcttacc tggcgatagt cgtttggatg cagaagagat aaaatctcgc atgcttagac
    11821 tgcttgggcg aaataaccaa ataaaggctc agattttggt agataattca ataggacgag
    11881 aagtctatag agttgctatc aacattacag aaacactatt ttaaagggga cctaaatggc
    11941 aaacacaaaa aaaggaacaa ctattgaaat tacaacaggt aaaccgattg taggaaaaaa
    12001 gattttttac tttatacaat cagttgatgc accaaagaaa agtcaggctc tgttgccagc
    12061 ctatcgtacc gatggtacta caaccatggg tggtgaatac attgatgagc aaacccaaca
    12121 aggtcgcgtt attgagaagg ctacagatga acactctatt gatttgacaa cgtactttgt
    12181 accgacagat ccatctgttg ctgtcatcga ggaagctaag aaaacaggta aatctatcaa
    12241 aatttgggaa gttattgccg acgaaagtgt caaagaacag attcaaattc ctgaatcgac
    12301 tggacccaag aaagatgttt accctgctaa gtttgggtac gccaagattg acgaaatcga
    12361 acgcggtact ggtatttcag acttagtaga aatgtcctac accgctaaca ttgtaggggc
    12421 cttacaagat ggtaaattcc ctctcacgaa agaagaaatt gaaatgctag aaaatgtata
    12481 cggctatcaa aatccgggtg atactactgg cgactacgat aatatcacta aatagcacac
    12541 aggggtggca actgctaccc cattttgatt taaaaaggag ataaaataat ggaatttaca
    12601 gcagcaaaac gaaatatcga tattaaattt gattttaaaa ctatgtttaa gatcaataat
    12661 aaactaggaa caattaaccc agaaacagga gagcgcaatg cagatggtgt gggtgctttg
    12721 tttttcaata tcttagagcg taatgaaagc gccattgttg accttgtgcg tttatctgcg
    12781 ggaagcggaa aaaaagcgct aactgaagat gaaattctag atgcaattgc agaagctgtt
    12841 gatgaagaag gaacaacaga agggttgttt gctgagattg aaaaagaaat ggttgattct
    12901 ggttttttca gagcgaagat tttgaaatat atcgaaaaca tggagaaatc agctcgttat
    12961 ctcaaagcga aggacgatat ggacgcaact caaatccaaa ttatcgaaga catgattgga
    13021 agaatgagca acgcagtatc ttagtaaatt gcgcacggct agggctcaca gacattgata
    13081 ctatctataa atgtactaag tgggagctag aggctattat ggaggggctt gagtataagc
    13141 agcttgctga gcgcgagaac ctctctgaat tgtctctaaa gcttagatat acattaaatg
    13201 ctaaaaaggt tgatgtaggt aagctcaaat acgataagca taggctaact atcaaaagat
    13261 cgtatcaaaa agctagccgt agccaagccg atagtgatag cagtattgtt gagagaatac
    13321 aaatgcttaa taatcatttt caaaatagat agataaggag gagtagatgc caggaacatt
    13381 tgatggttct attttcgctg atgttggtgc caacacaaag gactatgagc aggccatggc
    13441 tcgtattgtt agtacgactc agaatacttt cagaaaagcc caagatacag cggttaacag
    13501 tagtaataaa atggttcaaa tcattggaca aatcatggcc caactggcga acaacggcga
    13561 atcgctcggg aagagacttg gctctgccta cgctactggt ttaaaactga gcattggtga
    13621 aattcaacgc atagcagctt ccattggcga aaaaattccc gaacccataa agaatggttt
    13681 tcaaaaaatc attattccag ttgcaagtgt tattgacaaa atacggggta acttaaccgg
    13741 tttcattaat caaacaaaaa tgcaacttca gaatcttgtg ggtattggta agataagatc
    13801 tgcatttgcc aaggctgcga ctggagttga tatcttaact cagagggcaa gtagtaagct
    13861 taataactta tctgcaatat tcgaaacggt cgcaggcaag cttccgcgac cattcggaac
    13921 agcgtttaga aaaattgcct catccgtttc taccttgaat agctctatac agtctgttgg
    13981 agggaagatt tctaattcac ttggtcagca agtcttgaac ccagccttac agtcatggaa
    14041 taattttttt agttctgtat cagctaaggc gtctgctttc gcaaacaaag tgagtactag
    14101 tttgtttggt cggctgacct caagtttagc taatttatca agtaaaatag ggagcagtct
    14161 tagcaatggt tttagcagaa tgtctagttc tgcggctact tccttgaatg gaataagcca
    14221 gaaattcgcc aatacctctt ctgctggaga gagactcaaa agtacagtga tgagcatcgt
    14281 gcaggccttt agtttaatgg ctgttgctca aaaagctatg cacgctatta ctggggcaat
    14341 agacggggcg gttagtcgcg ttgataccat gaaccgcttt ccgaaaacga tggcgctatt
    14401 tgggtattct gctgaacaat ctaaggcatc aattgataag ctatcaaaag gaattgaagg
    14461 tctgccaact cctctagaca gtgctgtaaa aagcgctcaa cagctcgcca taaccacagg
    14521 aagtttagat aaagggacta gtttagccct cgccttcaat aacgcaatga tcggttacgg
    14581 ggcaacaact gaaggggctg agcaagcact caggcagttt aaccagtcgt tggggtctgg
    14641 aaaaattcaa gctgaagagt ttaactctgt atcagaagct gcgccaggtt taatgtctaa
    14701 aatggcggaa gccttcggtt ttggtaaaaa tggcgtacaa gatttaaaat cagtcttatc
    14761 tgatggcaaa atcactgcac aagagttcgc agataaaatg attgagctta acgatgccca
    14821 aggcggattt gcagagatgg cccaatcatc ggctggtgga atccgaactg catggaagaa
    14881 cgtacatacc gccgtcgtaa aaggcgtagc aggtatgatt tcagcctttg atgaagcggc
    14941 taaagctaat ggcatgaaga ccattgctga aacacttctt agtctgaagc cagcaataac
    15001 cagtgttttt gatacgatta attctcttat tccaaatgca gttgcagcat tcgctaggct
    15061 aaaacagtct atcaatattg actttagccc attaggcgcc agcgttaaag aggtgtttgc
    15121 tcttattaat attgtttttg gagattttgc acatactggt gaattatcag agcaggcttt
    15181 tgataatcta aaagcaaaaa tcacttcttt agctcctaaa gtcattgccc tttgggcagt
    15241 gatgaacccc gctagcgcta tatcaacgat aatgcctttg ctttctctat tcggaaaagt
    15301 tggtctagct ttaggaagct tagggacttc tgtcggggcg tttggcggca taatttctag
    15361 tgggatagct agtgccagcg gcgttgttgg tgcctttgcg gcaactctaa gcggattacc
    15421 tggcgttttt gctaccgcag cagggcgtgg gctatctgtg cttggaacta tgacaagcgc
    15481 aatgtccagt cttgtgagtt tagcactggc ggccatagga ccggccgcta ttctaggtct
    15541 tgtggtggca ggacttggtt tgattaatag tcagtttggc gcacaaatcg agcagctact
    15601 taacaccgca gttacaaaag gtcctggcat tattcaaggc cttgtaaaag gaattacttc
    15661 taaaatacca gttttgatag ctagtggcac tcaattgatt gctaaatttg caaatgctat
    15721 cgcagtgtta ttaccagtta taattcaagc tggcgttcag ctaattacga gtctcgtcca
    15781 aggtattgga caaaatgcaa cgaatttaat tagttcagca ataaaaatca ttggtagttt
    15841 tgttagttca attgcgagtg cattgccgca gcttatttct gttggaatgg agctattatt
    15901 aaatgttgtc aacggcatag ttcaaaatat acctcttatt atccagcaag cccagcaaat
    15961 tattgatagt tttgggaata gtttacaggc taaccttcct agtattatta gcaacggtat
    16021 agctattttg gtgaatcttg tacagggaat tactcaaatg ttgccaactg ttctgcagat
    16081 agctactcaa gtcattacga gttttgtatc tggaattgta cagtttttac cgcagttact
    16141 tcaaggtggc attcaaatca ttattagcct tgtgcagggg attattcaaa atctacccca
    16201 gattgcacaa tctgctgtac agattataca gtctttagct tctggactga cgcaagctct
    16261 acctcagatt atcgcagcag gcattcagct tgttgcgcaa ctagccgtag ccttgataaa
    16321 ggggcttcca cagattattt ctgcgggtat tcaattaatt atggggctcg gtaaagccat
    16381 gttaggggct atcccaaacg ctctttcagg agtttgggaa ggtattaaga gcggattcag
    16441 ttcgatgtgg gaccaaatca caggtaagag ttccacaagt acagctaaag tctctgcgga
    16501 cgccacggtc atggccatga atgttgggat gcaaacgaca gctatggcta atcaagctaa
    16561 tacagatacg acatctatgc ttaatagcat tagtcaaaat acagagcttg ctaatataaa
    16621 cgctacatca aatgccacac agatggctaa taacgttaat gctcagacag gaacgatgag
    16681 tcttcagggg ttgaatgatt cgatgtctct tgcgagtggc attagcacta atatgtctgt
    16741 cgctaatata aacgctacta ctcaggctcg agaaatggct tcaggggtta atggtgcgac
    16801 ttcttcaatg aatctagacg ccattaatca tacgctcagc ttagctagtg gtgttggtgc
    16861 gaacatggga gctgctagca caggtgcaac ttctcaggcg caagctatga gctcaggggt
    16921 gagtaacagc ctggcatcaa tgcagtcaaa ctcaactaaa gcagcctctg gtctgtctaa
    16981 tagtgtgaca agcgaaatgt cttctgcagc aacctctgca acctcaagcg ttaataggtt
    17041 gtcctcggcg gtcgagtctg gcttcaataa ggcgaagact tcagcaacaa cctcaatgaa
    17101 tgggatagcc aatgcggtta aaacaggatt tagtagcatt aacagtactg caaagcaatc
    17161 tatggcaaac cttgtaagtt cagtgacttc tgggatgtct cgtgcaaccg cggtgtctaa
    17221 taatgcttgt cagaagatcc tctcaatatt cagggctttg gcagggcaga tgtcttctgc
    17281 aggagcttat gcaggtcaag gttttgctaa tggtctagct agtagcgcag gcacaatcta
    17341 cgcaatagct aacagcattg ccgctaatgt agcagcaaca attagacgcg ctttagatat
    17401 tcactcacca tctcgtgtca ctaaaacact aggtgcattt actggagagg ggtttgccct
    17461 cggtatggca gagtggatag gtgagatcaa tagcctaggt aaagcatacg caacagcagt
    17521 tactgatcaa aactgggggg taaatagtac tgtttcaaca tctgctaaag ttaataatag
    17581 tggaatcaat acctctcttg ataatcttag cgaagaggtt aggcagtctc aattgtcaga
    17641 gcctatcttt gaagtgcata atgagattgt tggagataaa atttacacgg ctgttaaaga
    17701 aaaagaatca agagagcaat ctaaagattc ttattttgtt tttgactaga agggagtatt
    17761 ttggatttat taatagaaaa agagagtcag gcaactaggt tgtctgactt tggtatttat
    17821 aatattgcta ttgaagatag cgctccttta ctatctgtat cacaccgagc agtcaaagga
    17881 aggagtggtt acatctacga tggggctact tttacgacta aaacgcttaa ggtcaaagga
    17941 agagtgacgg taagcaacgt ggaaagactt ttggacaaac aggacgaact aaacgctctg
    18001 cttgttgttg acgaaccttt ctacgtgact aagatgtacc ctgaaaactc agatctattt
    18061 aactttgagc ttccagggga aagcacagga gacctgcaac ttattggctc tcctcataaa
    18121 ccttggaaat atagatttaa agtcatctta gacgacacta tcgcttatga atttatagga
    18181 aaaaccagtc aaggactaaa atataatctt tccttcgcgc taagaactgc tgaattacct
    18241 ttcggtgaga caaagccaaa ggacataact ctatcagggg gcagttttgc ctatgcagga
    18301 accgctaaag caagtcagct agagtggcct tttattatag agcttactcc ttctggaggt
    18361 cagactaatt tttatattga aattgatggc aggcgctttg agtttaagca gaatagccag
    18421 ctacaaaata gtgataaatt acttttgaca ggcatagcta ccacactaaa cggaaattat
    18481 gtcaatgcta aaacgaacta tgagtatttt atcttcaatc ctaatcctaa caagagaatt
    18541 acttacaaaa cggattttct tggcacgatt aggattttaa attttgtaga gttgtataaa
    18601 tagggaggtc taatgattac ttttttggat catcgtgaca ttgagtatgg ggtcattagt
    18661 gtcattaggc atactaatgc tgttaatggt gagcgctcag tgagcgggga aatttataca
    18721 aacagtgatg tcctcaataa tatcgataga gggtggcgac ttagatttga agatgagtat
    18781 tacgttgtta tttacgcaaa gcctgttgat gttggtcaaa aaacgcaagt ttcgtttgat
    18841 gccatacacc aatttttttg ggacttcagc aagagtagta tctatgaggg tctcggagat
    18901 gggtctcata ccattgatac ctatctagag acagtattta aaggtagtgg gtaccgctat
    18961 aagctagaag taggtgtgaa cgcatttaga aaacaatctt ttaattataa gtccaggtta
    19021 gatttattca atgagattat taaagcgacc ggacttgaat tttcagtcag cgggaaagtt
    19081 gttcggctat taaaaaacat aggtactgat ctgtcaacag tggtacgaaa aaatttcaac
    19141 atgaatgacc ttaccattga aaagaatatt gatagcttta ttacctatca gaaaggcttt
    19201 ggtgcatgga ccgacccaga ggaccactct aaggggagac ttgaggcgga atacgaaagt
    19261 cctcttgcca aggagtacgg tcgacttgaa ggggcgcctc tgacggatga gcgcttcacg
    19321 gtggcagata atctaaaaga agctttaaaa agtaatgttg aaaattcata taagatatca
    19381 gtaaaaattg atatggaaga tttaacgaga gctgggtata gatgtgagag gccggttgct
    19441 ggtgactaca ttatggcgat aaatgagact ttaggttttc aagagcgtat acggatagtt
    19501 tcttttacaa gctactacga cgcaactgga gctttagtaa aacatgaagt cacttgtaat
    19561 gatatcggat ctgtgaaaaa acaaagcgta ggaagtctgt ctataaacag tagaatcaat
    19621 cagatagatg cagatattgc ttctgcaatt gaagtagcaa cacaagcact agtatctgct
    19681 gacgggaaaa atactgttta cggtggcaca gaaatgccca aagatgaacc aaaaggaacc
    19741 ttaaaaaaag gagacatatt attcctaaaa gttggcgata ctactagaat gtatttctgg
    19801 aatggtgctg agtgggaaga acctgaggtt gtgaacgacc cagaacgatg gcgtgaagac
    19861 ctcgaaaaac aaatctctga ggcgatcgaa aaagccaaaa aagcacagga agaaatcaac
    19921 caacgcaccg ataaagagct tgaagaattt agagccgccc tcaaaaacct agcgttacca
    19981 gaggaagcga ttaaaaaaat cacagaggct ataaaagttg atgacatccc gtctattaaa
    20041 caaagctttg atgacctcaa aaatagagtg agtgagacaa gcgaagaatc tcgtttaact
    20101 gccgaaattt tagggaacaa cggtaagaca cgctacaaca aaaatttgct ggtcggtgag
    20161 cctaatcgtg ttaaaaaaat tgatgaggat tttatcgagg tagaagctaa tgatggtggt
    20221 ttcaagcgtg gcgagactta cacaatcagc tttagtcaga catgtgagcc gctcaaaaaa
    20281 gtggctatca cgctgatcca agctaataat aagggagtta aactggtact gacacctact
    20341 aaggcaaaaa tggagcctga gacttttact ctaattaagg acacagaggt catcaacgtc
    20401 tatcctttga gctactcagt cactttaagt ggtgactggt acaaatctaa gcaagtagat
    20461 ttaaatgcgt cggaggtgcg aaatatggct ctggggatga gttatagaga tgtggttgat
    20521 ggtaataatg ctgatttaat tttggactgg gcggaaaacc cagatattat ttttgacgga
    20581 aacggaggta tttaatgtca aaagaagttg catcagcaag gatacagcat agaggcatga
    20641 ccaaacaaga gtgggaatca agctccgata tcttaatgga gcgagaaatt ggaattgata
    20701 tgactacggg ttacccaaaa gttggtgatg gcaaaaataa gttcaaggac ttaaaagact
    20761 tgcgcggccc tatgggacct caaggtcctt caggagaaag aggcctaact ggcccaattg
    20821 gtcctcgggg ccctgctggc aagcctggaa cgacagatta taatcaactc caaaataaac
    20881 caaatctaga tgcgtttgca caaaaaaaag aaactaatag taaaatcacc aaattagaat
    20941 caagcaaagc agataaaagc gctgtttact caaaagcaga gtcaaaaata gagctagaca
    21001 aaaaattgag tttgacaggc ggcatagtga caggacaact acagtttaaa cctaataaaa
    21061 gtggtattaa accctcatct tccgtaggag gagcgattaa cattgatatg tctaaatcgg
    21121 aaggtgctgg tgttgttgtc tattctaaca atgataccag tgatgggccg ttaatgagct
    21181 tgcggacggg taaagagacc ttcaataaat cagcgctttt tgtcgattat aagggaacaa
    21241 caaatgccgt taatattgtg atgcgtcagc caaccacccc caatttttca tcggcgctta
    21301 atattactag cgacaatgaa aatggtagtg caatgcagct acgagggtca gaaaaagcgc
    21361 taggaacgct caaaatcaca cacgaaaacc caaacgttga ggcaaaatac gatgaaaacg
    21421 ctacagcgtt atctattgat atcgttaaaa aacagaaagg cggaaaaggt actgctgctc
    21481 aaggaatcta cattaactca acatcaggca cgacagggaa gttgcttagg attagaaacc
    21541 ttagtgatga taagttctac gtcaagtctg acggtggttt ttatgccaag gaaacttcgc
    21601 agattgatgg caacctgaaa ctcaaggacc ccacagcgaa tgatcatgcg gcaaccaaag
    21661 cttatgtaga taaagcaatt tctgagttaa aaaaactcat actaaaaaaa tagattaagg
    21721 aggataaatg agcagagacc caacacttat tttagacgag tcaaacctcg ttattggtaa
    21781 ggatggacgt gtgcattaca catttaccgc agaggacgac aacccaaaag tcagactagc
    21841 tagcaagtgt ctaggcacag cgcattttaa tcagctcatg attgagcgag gagaccaagc
    21901 tactagctat gttgcgccag tagtagttga gggtacaggt aatccgactg gactatttaa
    21961 agacctcaaa gagattagcc tagagctgac agatactgct aattcccagc tttggtcaaa
    22021 aatcaagctg actaaccgtg gtatgttgca ggaatactac gacggtaaga tcaagaccga
    22081 gatagtcaac tccgccagag gtgtcgctac acgtatcagc gaggatactg ataaaaagct
    22141 agcgctcatc aatgacacca ttgatggtat caggcgtgag tatcgagatg ctgataggaa
    22201 gctatccgca agctatcagg caggcatcga ggggctaaaa gccacaatgg ccaatgataa
    22261 aatcggttta caagctgaga ttaaagcctc agcacaaggg ctatcgcaaa agtatgatga
    22321 tgagttgcgc aagctatcgg ctaagatcac aacaacctca agcggcacta cagaggccta
    22381 cgagagtaag cttgcgggct tacgtgctga gtttactcgc tcaaatcaag gcacgaggac
    22441 agagctcgag tcacaaatta gcgggctaag agcggtacag cagtcaacag ctagccaaat
    22501 ctctcaagag attagagacc gtgaaggtgc tgtcagtcgt gtgcagcaga gtttggagag
    22561 ttaccaaagg cggatgcagg acgcagaaga aaactatagt agcttgaccc atacggttag
    22621 agggctacag agcgacgttg gatctccgac tggtaaaatc caatcgcgcc ttactcaact
    22681 agcaggacaa attgagcagc gggttactag agatggtgtc atgagtatta ttagtggcgc
    22741 tggagacagc attaaattag ctatccaaaa ggctggcggc attaatgcca aaatgtctgg
    22801 taatgagatt atctcagcaa ttaacctcaa ctcctacgga gtaacaatcg caggtaaaca
    22861 catcgctctc gatggcaata cgactgtcaa cggcaccttt accacaaaga tagcagaggc
    22921 tatcaagatt agggctgatc agattattgc aggcacgatt gacgctgcta ggattagagt
    22981 gattaacctt aacgcaagta gtatcgttgg tttagacgct aactttatca aagctaaaat
    23041 tggctatgct atcactgatt tgctcgaggg taaggtcatt aaggctcgta atggagcgat
    23101 gcttatcgac ttaaatacag ctaagatgga ctttaatagc gatgccacaa ttaattttaa
    23161 tagcaaaaac aatgccttag tacgtaaaga tggcacacat actgcctttg tacattttag
    23221 taatgcgacg cccaaaggtt atacagggtc agcgttgtat gcatcgatcg ggataacctc
    23281 atctggtgac ggtgttaact cggcttcttc cggtcgtttt gcagggctaa ggtcatttag
    23341 gtacgctacg ggatataatc atactgctgc agtcgaccaa accgagctat acggtgataa
    23401 tgtcttgatt gcagatgact ttagcatcaa tcgaggattt aaatttagac cagacaagat
    23461 gcaaaaaatg cttgacatga acgacttgta tgcggctgta gtagccttag gccgctgttg
    23521 ggggcacttg gctaacgtcg gctggaatac tgctcatagc aattttacaa gtgcggtcac
    23581 taacgagtta aataatcata tcaacaaaat ttaataggag aaacaatgga tttaacgctt
    23641 aaaaacaaag atttaaacac actatatagt gtactagaca aaatcaaagt cacgaacatg
    23701 cgagcaaacc gcggacgtgc taagctactc gcaaaagtag tcgataaatt caaagagtac
    23761 gccaaggatg agggtgacct tattgatctg tatgctcaaa aagacaaaga tggcaagttt
    23821 gtcattgatg agcacaaaaa catcaagcta gcagaccccg ctaaactcga cgagttcaac
    23881 ggcctactca acgagctagc tgatgaagaa attgtgatta aagggggtga gtactccaag
    23941 cgatttattg actttttaaa ctttttagaa gagtgtgaag atgaatttac atcatctgaa
    24001 atcattctta tcgacaacat tttggaacaa tttgaagaaa gtaaaaaagg agaaaaacca
    24061 tgagaaattg gaaagtgaca ggaaaatacc cacaatttga cagcacagga gcagtcgcaa
    24121 gcacacatat tattatcact gctgaggatg gctcagtcat ctctcaacca atcaagcagg
    24181 gcttaacttc aactaatgac acagagatta tcaaagctac tttggaagaa tttaaaaaat
    24241 ctgaatacgt cgaaatcgct atgggcgaag ccgtgcaaaa agtagacgac cttgaaaaaa
    24301 tctcacagga aaccgctaag accgctaaaa cagcccaaac agccgcagga ttagctaagg
    24361 tgtccgcaga gcgtacacag cggatgatta acttgcaaac catccacgta ttgacaagtg
    24421 gtgggaaagt tgaacccgat atctacaaag gtatgttaga gcttattgaa cctgctaaac
    24481 aaggcgagta tcaggcttat gacgtgttta ctgttgtaga tgagtcgcac gaagatcaag
    24541 cgggagaagg taatcttgtc tttgtacacg ttaacgagcc gtttacttat gacaaacaga
    24601 cgcttaaaga gctagaggaa gaggataaag tcacagtcat taagtatgcg gacttagtta
    24661 agcaggatta gcgaggtaag ctatggcaac agagttgata tttggtcttg gtggctttat
    24721 tttagctatc gtcacgactt acaatatttt taatgcaaaa tccatcaagc atgcgacaga
    24781 tattactttg ttgcagtctg aagtagagca tttaaaaatt gttacacgcc aaaatgctcg
    24841 gcgtcttgag gagcatgatg agcaaaacaa aacgctcatc acaatgacag agcaaattaa
    24901 aaacctcaat cgtgaggtaa gagaacttaa agatattatg agaggtgaag catgatcaat
    24961 ttaaaattac gactacaaaa caaagtaacc ttgatggcta ttttaggagc tatcttttta
    25021 ctggcacagc aattaggtat taaactacca tcaaacatcg cggatattgc aaacacagct
    25081 gtaacgcttt tggtattgct cggtgttgtc acagatccaa ccacgaaagg cctgtcagac
    25141 agtgagcaag ctttgactta ccacgaacca aaacaatagg aggggacatg cgggcaatca
    25201 cacgattagc attagttata gcaatagcaa tactgtatgt gccattatct gttgttgctt
    25261 tgattttaag cccattttta gataaggagg gataaatggc tacatatcag gaatataaaa
    25321 gtcgttcaaa tggcaatgct tacgatattg atggatcgct tggtgcgcaa tgttgggatg
    25381 gctacgcaga ctactgtaag tatctaggac tgccatacgc aaactgtaca aatacaggat
    25441 atgcaaggga tatatgggaa caacgtcaca aaaatggtat tttaaactac tttgacgaag
    25501 tagagactat gcaagctgga gatgtcgcaa tttttatggt agttgcaggt gttacaccgt
    25561 atagccatgt ggctattttt gatagtgatg caggtagtgg atacggatgg tttttaggtc
    25621 aaaaccaggg tggagcaaac ggagcatata atttagtaaa aataccatat tcaacgactt
    25681 atcctactgc atttagacca aaagttttta aaaatgcagt tactgttata ggtaatatag
    25741 gactaaataa aggcgattat tttattgatg tatcagctta tcaacaagca gacttaaccg
    25801 ctacttgtca gcaagctggc actactaaaa cgattatcaa agtatccgag tcactcgctt
    25861 ggctgtctga taggcatcag caacaagcta atactagtga ccctattggt tattatcact
    25921 ttggacgatt tggaggagat agcaacttag cgcaacgaga agcagattta tttctgtcca
    25981 atttaccaac caaaaaagtc tcttacttag tcattgatta tgaagactct gcaagtgccg
    26041 acaaagaagc taacactaat gcagttattg cgtttatgga taaaattgca aacgctggat
    26101 ataagcctgt ttattacagc tataaaccat ttacgcttaa taatattgat tatcagcaaa
    26161 ttatcgctaa gtacccaaac agcatttgga tagctggtta tccagactac gaagtacgaa
    26221 cagagccact ttgggagttc ttcccttcaa tggatggtgt gcgctggtgg cagttcacaa
    26281 gtgtaggagt agcaggtggt ttagataaaa atattgtatt attagcagat gatagtagca
    26341 aagtggatat acctaagatt gacaaaccac aaagccagct tacttttaat caaaagctag
    26401 atactaacac taaattagac aactcgaatg taccttacta cgaagcaacc cttagcacag
    26461 actattatgt agagtctaag ccaaacgcaa gtagcgctga taaagaattt atcaaggcag
    26521 gaactcgtgt aagagtctat gaaaaagtga atggatggtc acgtattaac gcttctcagt
    26581 ctgaccagtg ggtcgaagat aagtatttat ctaatgcaac acaagtataa aataggaggt
    26641 aaagctcctt tagataagac aaatgccctc gcttttgcgg gggctgtttt tgttataaag
    26701 attttaattg ttatttaagc attttcgttg atttttttct tttttgtgct aaaatatttt
    26761 gtgatttctt attattaaag aagaataggg tacacttata agtgagaaaa attgtaaatg
    26821 ttaattttaa a
//
LOCUS       DARYUW010000030        25366 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYUW010000030 DARYUW010000000
VERSION     DARYUW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25366
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVW11_001131"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVW11_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1365234.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TVW11_001132"
     CDS             complement(1584..2021)
                     /locus_tag="TVW11_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1365235.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TVW11_001133"
     CDS             complement(2008..3234)
                     /locus_tag="TVW11_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1365236.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVW11_001134"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVW11_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1365237.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVW11_001135"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVW11_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1365238.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TVW11_001136"
     CDS             complement(5505..6662)
                     /locus_tag="TVW11_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1365239.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVW11_001137"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVW11_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1365240.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TVW11_001138"
     CDS             complement(7553..8392)
                     /locus_tag="TVW11_001138"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1365241.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TVW11_001139"
     CDS             8708..10276
                     /locus_tag="TVW11_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1365242.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TVW11_001140"
     CDS             10269..11009
                     /locus_tag="TVW11_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1365243.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TVW11_001141"
     CDS             11357..11473
                     /locus_tag="TVW11_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1365244.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TVW11_001142"
     CDS             complement(11997..12887)
                     /locus_tag="TVW11_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1365245.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TVW11_001143"
     CDS             complement(13150..14814)
                     /locus_tag="TVW11_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1365246.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TVW11_001144"
     CDS             complement(14814..15179)
                     /locus_tag="TVW11_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1365247.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TVW11_001145"
     CDS             complement(15331..15519)
                     /locus_tag="TVW11_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1365248.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TVW11_001146"
     CDS             complement(15979..16344)
                     /locus_tag="TVW11_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365249.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TVW11_001147"
     CDS             complement(16934..17815)
                     /locus_tag="TVW11_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1365250.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TVW11_001148"
     tRNA            complement(18018..18103)
                     /locus_tag="TVW11_001148"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TVW11_001149"
     CDS             complement(18158..19084)
                     /locus_tag="TVW11_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1365251.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TVW11_001150"
     CDS             complement(19444..21057)
                     /locus_tag="TVW11_001150"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1365252.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TVW11_001151"
     CDS             complement(21331..21897)
                     /locus_tag="TVW11_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1365253.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TVW11_001152"
     CDS             complement(22164..23447)
                     /locus_tag="TVW11_001152"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1365254.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TVW11_001153"
     CDS             complement(23796..25205)
                     /locus_tag="TVW11_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1365255.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
BASE COUNT         7500 a         6056 c         4642 g         7168 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat gctgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggtgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat tttttt
//
LOCUS       DARYUW010000031        24289 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYUW010000031 DARYUW010000000
VERSION     DARYUW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24289
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(230..1909)
                     /locus_tag="TVW11_001154"
     CDS             complement(230..1909)
                     /locus_tag="TVW11_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365256.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(2084..6988)
                     /locus_tag="TVW11_001155"
     CDS             complement(2084..6988)
                     /locus_tag="TVW11_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1365257.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            7341..8168
                     /locus_tag="TVW11_001156"
     CDS             7341..8168
                     /locus_tag="TVW11_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1365258.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(8244..8597)
                     /locus_tag="TVW11_001157"
     CDS             complement(8244..8597)
                     /locus_tag="TVW11_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1365259.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(8601..9113)
                     /locus_tag="TVW11_001158"
     CDS             complement(8601..9113)
                     /locus_tag="TVW11_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1365260.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(9570..10124)
                     /locus_tag="TVW11_001159"
     CDS             complement(9570..10124)
                     /locus_tag="TVW11_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1365261.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            10335..10964
                     /locus_tag="TVW11_001160"
     CDS             10335..10964
                     /locus_tag="TVW11_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1365262.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            11423..12508
                     /locus_tag="TVW11_001161"
     CDS             11423..12508
                     /locus_tag="TVW11_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365263.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            12694..13932
                     /locus_tag="TVW11_001162"
     CDS             12694..13932
                     /locus_tag="TVW11_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1365264.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPQGERGEQGPRGENPTPTPDPMPQPMPD
                     PAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVL
                     GTGLLSLLGLGFLTRRKRKQ"
     gene            14250..15545
                     /locus_tag="TVW11_001163"
     CDS             14250..15545
                     /locus_tag="TVW11_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1365265.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPDPQPKPEPKPQPEPKPEPKPQPVPKPDPEPMPDPEPKP
                     QPEPKPEPQPEPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQ
                     SSGKGLPRTNEAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(15678..16796)
                     /locus_tag="TVW11_001164"
     CDS             complement(15678..16796)
                     /locus_tag="TVW11_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365266.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(16793..17920)
                     /locus_tag="TVW11_001165"
     CDS             complement(16793..17920)
                     /locus_tag="TVW11_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365267.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(17929..18852)
                     /locus_tag="TVW11_001166"
     CDS             complement(17929..18852)
                     /locus_tag="TVW11_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365268.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(18875..19561)
                     /locus_tag="TVW11_001167"
     CDS             complement(18875..19561)
                     /locus_tag="TVW11_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1365269.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(19558..20229)
                     /locus_tag="TVW11_001168"
     CDS             complement(19558..20229)
                     /locus_tag="TVW11_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1365270.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(20204..21562)
                     /locus_tag="TVW11_001169"
     CDS             complement(20204..21562)
                     /locus_tag="TVW11_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1365271.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(21575..22639)
                     /locus_tag="TVW11_001170"
     CDS             complement(21575..22639)
                     /locus_tag="TVW11_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1365272.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(22636..23586)
                     /locus_tag="TVW11_001171"
     CDS             complement(22636..23586)
                     /locus_tag="TVW11_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1365273.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(23814..23978)
                     /locus_tag="TVW11_001172"
     CDS             complement(23814..23978)
                     /locus_tag="TVW11_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1365274.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
BASE COUNT         7381 a         5671 c         4717 g         6520 t
ORIGIN      
        1 attttaaaag gcaaacaaaa accatgccac attgcaatga catggttttc ttcaagaaag
       61 gagcgagctt tggtttggta ctttctacaa ctgatctcca atagcagctg ctcctcgtta
      121 gtccctgagc cacaggtgac tgagctttcc tgcggctact ctgatagtac cagctactct
      181 tacaactgca taaagcagtg gctgccagcc aagctaaagc taaacaatat tactctgtta
      241 tagcttggtc tgctgacgag ctctcaatgg tcatgtgatt gaggtagttg tcatcagcca
      301 gctgagcctt aaactggtct ccgaccttta ggaaaggcag acggtcacta gtttcactgc
      361 ttgccttgat tttataaatc tgacccttgg aggaaatgta ataaaccgtt gttcctgaga
      421 taatctggct ggccaattgc tccacctgcc cagtaatcat cttgaccttc tgatcattgg
      481 tgtctgacac tgacagcgag cttgtgtcct tatctgtgaa ttgtgagatt aaggtctgaa
      541 tgtcattatt cactgttacc tgctgataat cctctgcatc aaccaaggca taggatttta
      601 tcagaccagc cccgtccttc aatgagataa ggtaataagc cttgtcattt aacttgacta
      661 gggttggtgc agttgcagtg tatttcttct cttgaacttc gccctcggct gatttcatgg
      721 cagaggcctc tgttgcagaa ggcagcttat agttagtgac ctctctggta cgcatgttaa
      781 ccaaaataaa gccgagattt gacgaatcag ctgttgctga ggtgattcct gtatagaggt
      841 aaatgtctga gccgatggta atgtagttat agctgtctgt tgtttgcttg acatctgtct
      901 ggctaaagac agtgttccaa tagccctttt gataggtgta atagtcatta accctctcca
      961 aaacattgtc agcagaatag acacgatcaa cccattttgg aacgtccttt agctcatagt
     1021 attgagactt gccgctaacc gcgtctaaca ggatcacacc cgtcggctcc tgagaggaca
     1081 ggccaaattt tggggcgtag gttgttgcga catagtaagg gttaccatcg tcatcaacct
     1141 caaatgacgg gtctgaaaaa atggtcatcg ggtactggaa gcgcaaatgc ctcatggtgt
     1201 ctctaaacat aaattccgaa tgagaatact tcataggctg atttaacttg actagctctg
     1261 ccttaccagt tgtctgattg accttgacat aatagccaat gccgtcctta cgattggtta
     1321 gccatttcca gaaggatttg tactccaagg gagaaacacg ataagggagc ttgccgatcg
     1381 taatctgacg gtactcatca gaaataccaa actgcgatac cttatcaatg gtcccaagat
     1441 aagtatctcc aatcttttca gccgaatctc gatccagcaa tgccaaggct gacagatcag
     1501 tgtctggaaa atccttgtta aaatcagcgt cctttacctt aatcacatga gcataggact
     1561 tagcacgaaa cattctagta ttaacagcta acagcaagga caagccagca atgataacag
     1621 caagggcaag accaagccac tttatgccac cggttaattg cttgagtgaa agacctgagg
     1681 tcacgtcctt gcggccagac ttttgcgtga aaaagctggt cactgttttt ttcaacccaa
     1741 acaaggacag gataaaaaga ctcaccatcg ccaagataag cgcaagaatc acgaaaaacc
     1801 aaaattctaa gctcatcacg ttcattggcg gcaaataaat ccagtaaaag ccagccagga
     1861 tcaagctgtc taagccaatc agcaccaaag aagcaacttt ttttgtcata ctaatctcct
     1921 cgtcacaccc taaggctatc aggggtattc aatatcttct caccgctatt gtaccacatt
     1981 tcccctcaaa agatgacatc tcagccagac atttttatca gctcttagag cacctcagct
     2041 agaatgatca atacagctga caggctacgc tcatagagct tgcttagtac ttcttttgac
     2101 gctggcaaga gcctgctgct ccaagactga gcaagcctag caggactaga ttgaccgctg
     2161 cttgctcacc cgttgatggt aggacttggg cttttttaac tgcttgtgct gttagggcag
     2221 agctagtgat tgatgagccg gtataatgag tcaagcctcc agcctgatgt tctagctgag
     2281 gctgcttagc tttgataacc tcaaaggtaa gctcaatcac gccattatgt gatacctcta
     2341 gacctccttg accgattagc tgatagccct ccggtagctc aacgaggacc tcatagcttc
     2401 cttgtcgcag tgttttacca taggcacttg gaacatagag agacggagct agagaaatca
     2461 actgaccatt tgctgctttc aggctgaccc tgctgccttc tggcaagact tggttaaaca
     2521 agagccaaac agaagccaca ataggccttg tcatctcaaa ggcaactgaa gcaagccttg
     2581 tatccgcatc tagactaaag ctaaccaagt tgtcagacct tagctcaaac agatgattat
     2641 cataagccaa gagctcaacg gtgtagcgtc caaatggcaa tatcaagcta ttagctgagc
     2701 tattgaaata gtccaactgc tcgattggct tgccctgctc atcacgaata agataagtaa
     2761 aggctggctc ttttttgttc tcaagcacat caagtgccaa ggcaacggac actactccct
     2821 tgtctggtcc tacagctcgc aaagcagcta agctcatata agcaatctga cctgcctcgt
     2881 cttccactag ataataataa tctgcttctg caacgccttc aaccttagga atggtgtagg
     2941 tgccgtctgc attttgagca atcatcacct tattatcctt gaatctgatc agctgatctt
     3001 cgacagttag atcaaacttg cgtccatctt tcttgacaag gtagaagacc tcttctctaa
     3061 caatacctat tggactttgt cccttgcttg gtcccggacg aaagacctca gtagcaccat
     3121 cagcttggaa gctagctggc gtaatgactg gcttttgatg gctaactgtc accgcatagg
     3181 cctctgcttg aggcatacca ttagcgtcta gataagaaac aacatagcga taatgtcctg
     3241 acatcaccct agctcctgag gctcttgtgc cataccaagc ggtgctgtca acattagcca
     3301 cgcttgcacc tggttggcta gaccagattg ggcttgtcat agctgtatcc tcctgggcaa
     3361 agaccgttac ctttagatct tgatatactt gatgtggcaa gcccttgaat gccacaaaat
     3421 ccttgtttcc atcatcattc ggcgagatga cagcagtttg acctaattta gccaaacgac
     3481 tctgtggtct attgcggcta ataatgagaa gctctgcttc atttgtcacc agtcctgtat
     3541 ctgcagcagt catgttgagg ttatcactgt agctcagctg atgctgagca ttaatatcag
     3601 ttagggtcaa tgccagctca gcctgaccga ttttttctgg caagtgattt cccagcttag
     3661 caatggcaac attgcctgca aaatcctcga ccatgtaata aaaatcacca agcgccacct
     3721 gatcaactgg caggacaaaa gagccatctg ctaagcgctc aacaaactgc ttattgtctg
     3781 atacggtcac atactttaag ccatcattaa tggtaatcgt ataaggcttg tcatcctttg
     3841 tttccaagta aaaaacacta tctcgaagaa caccagcctg accgcgatca agccactgag
     3901 acggtctgaa gcgatgggtc acagggttat agcttgctgt tcctagctcc ggcgtttgac
     3961 gatccacaat cacctcaaag accatttctt gacgtttcgc tcctaccaca tctggataat
     4021 aagaaaccac ataatggtat ttgccatctg gtaggtcagc tccggtcagc gatttaccac
     4081 taaagcctgt ttctaacagc gttgttgact tggcaaagcg aatatcactg ttaaagtttt
     4141 tatccccttg aagggctgat gggctcgtcc agagcaactc cttacggtct gtatctgttc
     4201 ccttatagac cctggcttgc aggccttggt atttacgtaa gaacacccct ttgaaggcag
     4261 caaagtcttg attgttgtcg ccatttggag agatagccaa cacaggatag ccaactgcat
     4321 ttcgctccaa cacaaattta ccgtctttat tacgaaaggt tcctagtgtg tgcaagccat
     4381 tgtcagcaat agtagtcata gagacattgg tatctgtacc aacagtcacc agcccagtaa
     4441 aatgattgcc gacataaatc tcgtccttta gccctgagct gtcaaaataa aagccagttt
     4501 ttccttgagc ctttagctca taaatagagg cttcaacaac aggtaggttt tcaaaggctc
     4561 ccttaaagcc aacaaatgga atgttgatgt tatccttgtg ctcgtccttg ctatccacaa
     4621 agcgaacaaa gccctctaga taatagccat ttggcatttg cttagagagt tcctctgtaa
     4681 agtttgaggc atctagggta atggtaatgg tcttgtgtcc ttgagcaggt acgtcaacct
     4741 gttctccctg ataggttttc agagatcttg aacgtaaggc aaaacgtcct tccttagtat
     4801 ccacctgatc agtcaacaat tctgtctggt agcgcagcga cttagcctga ttagacaagt
     4861 tatggattgt cacctcaaag cttatctgat cagtcacatt tccaagagaa atactgccat
     4921 agttgtcttt acctgtcagg tacagaccac tggttaccgc ggtctctata ttcaagagcc
     4981 ctgctccctg ctggcgtggc gatgtggtgg tattggtctt agggttgatg tggatctgag
     5041 cattactcat cagtatattt ttgaccagat ctgctagctt atccttggca agctgtggtt
     5101 gaagcgcttc tagatattgc ttgaccaaaa ggcttgcccc tgcaatgtgt ggggttgcca
     5161 tactagttcc tgactggctg ccatagtgat catcgttgaa ggtcgagtaa atatctccac
     5221 ctggagcagt gatgtcaggc ttcaaatagc catctgaggt caagccccag ttagagaaat
     5281 agttcatctc atttcccttt tggctaatgg ccttagagac ctcagcatca aaggtcagag
     5341 tgcctgttcc attgccattt aaagcagcca ttgccatgcc aaattcatga gagataaagg
     5401 cagatggcag caccatcccc tttgaactca gacgcatggt gcggttagcc ttgcctggct
     5461 cattgttaaa aatcaagacc ccagctgccc cgtactgctt ggcctctgct ataatatcgt
     5521 cgtatttccg attaggatca cgctgcacca agacaatctt gccactcact tcgcgttctt
     5581 ggtagccttc ttttgtcaaa gctttgacat aaacaaatga gtatggtaca tcaaagccaa
     5641 gactagtctt aatgtccttg aaatcaacag attccaaata gatagccttt ccatgattta
     5701 agtcagccct atctttcaag ccctccaccg tcatcagacg ctctataatc actttgttat
     5761 taatagacgc aactgaggta ggagtccggc ctgctgatgg agcccccact aagccataat
     5821 caggatttgt caccaacggg tctgcatgat ctgacccaaa ggcacgctca ttacctgcag
     5881 caacgaccac agagacacca gcctgccttg ccttttcgat agctgccatc agggcacgat
     5941 tcccattcaa ttgagaccca ttggccgagc ccagacttaa attaatcaca tcagcgccca
     6001 atgccacagc atcttcgatg gctttaataa ataaggggtc cccagttccc atcaaatcat
     6061 gggtaaaaac ccgcataaac atgacctgag cctcaggagc aatgcctaaa aagcgttcgc
     6121 cagctgctgc cgccttgagc ccatttccag ctgcaatgcc tgtcacatgc atgccatgcg
     6181 attcatattt gctgtcatca tctgtatctt gccagtcaat gatagttcct cctgatgtgt
     6241 catcaagctt gatgaccgtt tcctgaggtg cctctattga ctgcggacgg ttcctcctaa
     6301 tatcaatctg ctgcacaatc acatcaaaat ccaagtcgtc aaggccctca aacggatcgt
     6361 cctttatctc ctttacctta tcattgtttt ccacatagtt gtgggcaaag actaccttat
     6421 cgcttagcca gacaccgtac tgaatgcctg ctgctttttt gcgctggtca atatctgcct
     6481 ttgatgtaaa cttagcagct gctggatttg taatgcgcat ggcatggtga ctagcgtcaa
     6541 taccagtatc aataacagca ataaccttac cttgaccctt atagcctcta ttccaagctc
     6601 cttctgtttt tatccagcgg tgagtatcca tatttactgg aggtagctcg cgcgattctt
     6661 cttgctgctt gactgattgg ttagattccg ttagcgcttc catttcggaa gaaactaatc
     6721 cagtcgccat tgcctcctct gtcttttcct ctgctttact tgactggctg tcgatgtcct
     6781 gagcattaac agcagctccc tcactagcct gagagacaga caatacctcc cttgattctt
     6841 gatgttgtcc tgctgacacg tgagctgagc taactccctg ctcctcagcc acaactgatc
     6901 ccatccctgt cagaaaaagg attccgatca acacagaaac cattcctgat ttatatttcc
     6961 tcagtgagaa gcgttctttt ttctccactt gatgtcctcc tagatttatt aaaaaaggtt
     7021 attttaaaca aatgattcat ttatgtttta atcaataatg tctaagctat ttaaccattt
     7081 tttaatcaca aaagcaataa gactagaagc tctcagttta tgtcattttt taatcattca
     7141 actcactgaa atgaggcctc tcagaacctg tctcatcaac agataaggct aaactcagcc
     7201 gctagacttc aaaaatgtca caccattttt agacattacc tgtcctcata cctataacag
     7261 aaccaagctt ccacagtcgc cttggcctta tttttttgtt acaatatagg ttaagattat
     7321 catttagaaa gcgaagaaaa atgaaactca tctcatggaa cattgattct ttaaatgctg
     7381 cgctcactgg tgaatctcct agagccctct tatcacgcgc tgtacttgat actctcgtgg
     7441 cacaggacgc tgatattatt gcaattcaag agacaaagct atctgccaaa ggccctacca
     7501 aaaagcacct tgagagcttg cttggctact ttcctaatca tctcaatgtt tggcgttcat
     7561 ctgttgagcc cgccagaaaa ggctatgccg gaaccatgtt cctctataaa aaagagctca
     7621 atcccattgt cacattccca gatatcggag ctcctaccac tatggacgct gaagggcgta
     7681 tcatcaccct agaatttaac gatttctttg tcacacaggt ctacacccca aatgccggtg
     7741 atgggcttag acgcttggaa gagcgccagc tctgggacca aaaatatgcc gactacctag
     7801 cccagctcga tgcccaaaag cctgttttgg ctactggtga ttacaacgtt gcccacaagg
     7861 aaatcgacct ggctaaccca gctagcaacc accgctctcc gggctttaca gatgaggagc
     7921 ggcttggctt tacgaacctg cttaaccgag ggtttacaga tacctttcgc tttattcatg
     7981 gcgatattcc aaacgtttat agctggtggg cacagcgcag caagaccagt aaattgaaca
     8041 ataccggctg gagaattgat tactggctca cgtcaaatcg gttgattgat aaggttagtc
     8101 gctcagagat gatttcctca ggagaacgtc aggatcacac accgatttta ttagaaattg
     8161 atctatagac tagaagcatt cggacaaatc aacccagaca ttaaaaaaaa atggctctgc
     8221 aagagaaccg tttttttaat cgcttaaaga cctagatcct tataggctgt tcgataccct
     8281 acctgcaaga cctgattatc ctgtaagagg atcggccgct taatcagcat gccatctgtt
     8341 gccaaaagct ccgctgcctc ctcaacgctc agtgaattaa ccttatcttt aagcccaagc
     8401 tcacgataac gcataccact ggtattgaaa aagcttttga ggctataatc tgaatgctct
     8461 agccattgtt tcagctgctc agctttaggg ggattggcct taatatcaat gatatcaacc
     8521 tcagaaacca gggtctttag ctcagcaagg gctttttgac aggtactaca ctttgggtat
     8581 tggtaaatgg taatcattag ctactcctta ttaacactaa tttgctcgtg cctgagcaac
     8641 caggccttct tttcaagtcc tccagcatag ccaatcaagc gaccatcagc agccagtaca
     8701 cgatgacagg gaataaaaat acttaaagga ttacgtccta tggcaccacc aacagcctga
     8761 gccgaacgac actgcaggcg cttggcaagc tcaccatagc tcaaggtctc tccccatctt
     8821 atcgtctgca attctcgcca gacagctcgc tgaaaatcag taccctgtgg agataagcaa
     8881 tcaagcatgg gatagggctt cctctcaaag taagcgtcaa gccacaaaca ggctcttttt
     8941 aacagggcat gctgctcctg ccagatgggc tgcactttaa tcccagcctg aaaatacctt
     9001 tgaccttcaa accaggctcc tatcaaagca acatcagtcg caaccaagga tatttttcct
     9061 aagggcgatt gatacacaca ctcgtacaat ggcaagatct gacctcccca cataatagct
     9121 tattcccttg actatttatt ataagaaaaa gcctagctaa aggcaagaag gagccctctg
     9181 acaccacaac aaacgcatga aaaaacaata gcggctcttt caatgctgcc atacaatcgt
     9241 tagtgtcaaa agtcgcttac tatacagctg ccccccttga aaaacgaagc tggaaagaca
     9301 caacatgcta aagctgtttc acgcgctggt gcctgattag atgttcttct aattaaaggc
     9361 caatgttctg attaaaaagt catttcatgc gctgatacct actcaaataa aaacacatag
     9421 cgtggggcta gaccaatccc tcacaagtca tcaatagttc gtctatgagc tacactttat
     9481 cacattggga taggcagaca tatttgccgg ctcagttgta cttgcctgat agctaaccaa
     9541 aagcccgata agctttttcc gatcctatat caatagctgt agcggctatc ctcgctaatc
     9601 tcctgataag cggctctttc atggcttttc ttaatttttt gataggctaa gcgctcgcca
     9661 tcaattggta ccttgccaca gtaaacaaag cctaactttt caatgatatg ccgcatgacc
     9721 tgattatgct catgagtatc tatccgaaaa tctggtccat gctgcccctc aatgagccct
     9781 tgcaaaaagg tctgagcaat tccctgacca gtcctatcac tcagcaccgc cacacgatga
     9841 aaggtcacat aacggtggtg attatgctgc cacctgccat cataaatctt gtcgtaggcg
     9901 tcctcttggc catcaataac agccgcataa gcaacaatct gcccctcaag caaagccaca
     9961 tagccctgcc cttgcaacac atcagcagca atatcctgat aagcaggata cccatctgct
    10021 ttctgccatt ggctggagcc tgattgggct aaggcagact tagctgaatt gatcactgtc
    10081 atgatctgac taagctcatt aggaaaagca agtctaatct ccatcgttca cactcacaat
    10141 ctattctgat ttgatgatgc tatgctaccg caaaaagcct tacaccttgt cactctgcta
    10201 gggacacctc atagcggtat gcctgcttct catctcagct gagtatagca caatagtcat
    10261 catttgacaa aaagcctctt caaggattgc cagcaatcat gctataataa agtaaatcac
    10321 aaaggagaac cattatgatt aaagaatttt gtgctgaaaa cctaaccatg ctaaaccaat
    10381 tgaccagcca gtcggtcaat cgtgttgagc tctgcgacaa tcttgcagtc ggtggcacca
    10441 caccctctta tggtgtcatc aaggaagcct gcgacctcct acatgacaag cagattagtg
    10501 tcgcaacaat gatccgccca agaggaggtg attttgtcta taacgacctt gaattgcgtg
    10561 ctatggaagc agatatctta aaggctatcg aagcaggaac tgatgccttg gtcataggct
    10621 tactcactaa ggacaaccag cttgacaccg atgctatcga acagctccta ccagctacac
    10681 aaggactccc tctggttttt cacatggcct ttgacctgat tgctcgcgac caacaaatcg
    10741 caagcctaga gcagctcatt gactatggct ttgtacgaat cctgcttcat ggctcaagcg
    10801 ataccagatc catctatgaa aacattgacc atatcaagca gttagtcaag gctgctcagc
    10861 accgaatcga aatcatgatt ggtggaggtg tcacagctga taactgccaa gagctaagtc
    10921 aactaacagg aacagctatt gtgcatggca caaaaatcat ctaactatca gctcaaataa
    10981 aggaaaagtc actccctaca aggaggtaaa taatagcagc ccttctcgtt gaaggccata
    11041 cctgagccct tagactaggc tcctagcaaa ctaatagtat aggaccttcg ctgcctttac
    11101 atcaaaaagg ctgccgtcca gaaaaagaga aagccacaca ttgatagaaa accatagctg
    11161 gctctactac tatcagtatc tatcatcagc ttctgagctg cctaaaagtt tcggtgatca
    11221 ttaacaagta cagactattt gtttctaaat tagatcataa aacagacaat tataggaagc
    11281 gacaagtgaa tcattattca ttttttattg attactatga tactataagt aaggatagcg
    11341 ctttcttttt gtctttgctt tgcctgacta ttaggctcta gatttatttt ttaccatact
    11401 aatataagaa tcggaataaa taatgacaac aaggtatttt tataagctat tgctaacgat
    11461 gttgacacta gcattaggag gattttccct atctgcttgc cactccaaga ttagtaagcc
    11521 ctatcaagtc gctatttttg acaaggatca tgttaggacc tttatggaaa aagctgacag
    11581 tctggtgcct gttgagacca tctctcgaac acagcacaag ctatttgagc gagaaagctt
    11641 taagcaggcc aagcaagggt attttgcaaa gacaagagaa ggaaatgacc tcaaggttct
    11701 gttaactcac attgatcaag caagcctaga agaaaaagtc cttcatgctg atggcaatga
    11761 cgcctacacc tctacaactg atggtgatta cttttacaca acagctgtct ttgccgatcg
    11821 tattgactgc tacaagtatg accgccactt gaaaaaacag gctcacaagt ctattctaaa
    11881 tcaagacacc attaatgcca gcaatcagtt tctggtgatt gatgacgctc tgtacctgct
    11941 tgtcagcgct gtagacatca agagtcagca gcccaaaact gagctatgga aaatggacaa
    12001 atcctttact atcactgatc ggatagatct ggacgaaagc actgcctatc tgcgcatggt
    12061 caacgtcgga cgaacccttt acattaccca ggctgctgat ggcattttag aaactggaga
    12121 acctagacct ggtaacaagg tgatgaccta tgacttagat agcggtcaaa agtcctatct
    12181 catgcttcat gtcaatagtc ctagagccat ttaccaccat gccaaaacca atgagcttat
    12241 catcgaaaat gatcagcatt ataatcctga ctttgcatgg accatctacc agctagatac
    12301 cggagaggag agaaccattc gctttgagga gctagccggt caggagacaa gctctcccta
    12361 ctttatgatg acctcaagca actactactt cctctttcca aaaaggcttt accgatacga
    12421 ttgtagtaac catcagatga cctgcatcaa cctagatcag tacggagtga cgcacgccca
    12481 tgccttgatc gctaagccca caccataaat cacaacaggc ctaatcacca ctcattcatc
    12541 tacaccccaa tgcttagaca aagcagtgta ctgaccccca aaagttggac acgacatatt
    12601 agtgaaagga tttagttctg tattgcacag ggctaagtcc tttcactaat atgtcgtgtc
    12661 caacttttgg gggtcagtac actttgggaa agtatgtatg aatctccaga aaaaatacct
    12721 tatcaactac ctctatatga caagtatgag ggaaataata gtttatttag agataatgcc
    12781 tcaccaaatt ttagggcgga tgtcaaagat attacagcta ctttagtggc tgttttaagt
    12841 aatggttatc caaccgggaa aagcagtttt tgtaaagact actgtcccga tgaaatcagg
    12901 gcaagacaat taacccaatt agctatttgg tattttacag atggtatttc tgaagaaacg
    12961 ttgaaatcaa attatagtct aaatgatctt gaatttcaag gattaaagta tttaatacag
    13021 gctggcaaaa ctgctgggac tagtaacaat cgaactttag atatctatat atctaaagat
    13081 agaaattcaa aatttcaaaa tcttttaggt tctaccttag tagttaaaac tccagaaaac
    13141 aaagagaact gtcaatgtac taaaatttat atagaagaaa atggaaaaga tggttattat
    13201 ctttacatct atgaggatac gaataaaaac gataaatatg acaaaaacaa agataaacta
    13261 ctacagaaaa aatacataaa aaatgggaaa gacggcaagc ctggcctaaa tggtcaacgt
    13321 gggcctcagg gcgaacctgg gaaacaagga ccacaaggtc ctagaggtga taaaggggaa
    13381 accggagaaa aaggacaaga tggtaaaccg ggcaaacaag gtgatcgtgg tccggctgga
    13441 cctcaggggc ctagaggtga caaaggggaa actggagaaa aaggagaccc tggacgtaat
    13501 ggtaaagacg gtaaaccagg tgaaaaaggg gatcctgggc aacaaggcat tcctgggcct
    13561 aagggtgatc ctggaaaaga tggagaaaaa ggtgaacgtg gagagcaagg acctcaaggc
    13621 gaacgtgggg agcaaggacc tcgtggagaa aatcccactc ctaccccaga tccaatgcca
    13681 caaccaatgc ctgaccctgc acctaaacca gaatccaagc cagaacctaa gccgatacct
    13741 caaccagagg ttaagcctca gccagagaca aaacctcaac aaccaaacaa gccatcaacc
    13801 attactagcc aacctagcgg caaagcacta ccaaaaacaa acgacacagg cagcttgata
    13861 acagtattgg gaacaggctt gctctctctt cttggactgg gcttcttaac tagacgcaaa
    13921 agaaaacaat aattaaagca ctatctatag ctttttaatc attggctatc aaacaaatca
    13981 caaaaaagct tatcgtttta ctcctaacga taagcttttt cgtattctct attacttggt
    14041 cccaatacta tttttccagc tttaggctgg ttttgttaat ccaaaataat atcagacaat
    14101 ttccgtttta attaaaaaaa aaaaaaaaaa acgaaactgc ggaagctaat tatcagaaaa
    14161 tgattcacag cttagagtca ccatgttaag ctattctacg gagaagaaag gtttgggaat
    14221 gactatttct aaactcaaag gagagaaaca tgagaaaaac aatgaagaag atgctagcag
    14281 cctcgacagt ctgcatcatc atgtcgggca gctttatcgg aggcgcggca agagtactgg
    14341 cagagcagta ctatggctat gatgatggaa caaaagacgg tggagactgg ccagtatttt
    14401 tatatgtaac accaacaaat caccccgaaa gaaaaaccga taaagagcac tgtgtctatt
    14461 gctttaacag gttaaatagt tcacctgagc tctgggaatc tcaatttaaa gatccaagta
    14521 agctaggtat aaaactccct atctatgaaa agaaagaagg agatgaaagc cttttaagag
    14581 ctaaatctca gaagcccagt gataacttaa cttcaaaatt agttactgtt ctttcaaatg
    14641 gctatcctaa taagacatta ggtaatttaa gtgaagatca aagtcgccga ttaacacagc
    14701 tagctatttg gcactttact gatggatacg ctacaaatca tttcaaagat ggttatcatc
    14761 taaacaaaga tgaagattca gaattaaaaa agttaattga aactgctgaa aaaaacttcc
    14821 aaactacagc acatacctat agcttaaatc tttatgtaac ttcatcatat aattatagta
    14881 caggtaaatt ttatcaacat cttcttggtt ccactttaac accaaaactt ccgaacccaa
    14941 atccaggacc taaaccacca ggtgggaaca atccacatca tttaccaggt gaaaatggtc
    15001 aaactaaata tccagaagga gaaagcggtg aggcaggagc tcctaaaaag cccgagccta
    15061 aaccagagcc taagccggaa ccaatgccta agccagagcc taagccacaa cctgagccta
    15121 tgccagaacc taagccagat cctcagccta agccagagcc taaaccacaa cctgagccta
    15181 agccagagcc taaaccacaa cctgtgccta agccagatcc tgagcctatg ccagatcctg
    15241 agcctaagcc acaacctgag cctaaaccgg aacctcagcc agaaccaatg cctaagccag
    15301 agcctaagcc acaacctgag cctatgccag aacctaagcc taaaccggaa cctcagccta
    15361 aaccagcgcc tcaaccagag gttaagcctc aaaaaccaac caagccatca aacactacta
    15421 gccagtctag cggcaaggga ctaccaagaa caaatgaagc aggcagtcta atgacaggac
    15481 ttggaacagg cttactctct cttctcggat taggcttcct aacaagacgc aaaagaaaag
    15541 actaagacac taaaagatta tctatagtcg tttagttgat cagtatctag tctaatacaa
    15601 cacaaaagcc ttatcgcgcc ataaatggaa cgataaggct ttttaagctt ggttcaaaaa
    15661 gggtaagaca acttagtcta gcgatgtaaa ggcttcatca gcacgcttgc tagtaccatt
    15721 aaggtcatgg ctgctacaaa caaggccaag aaataaggcc aagcctcacc tagattaccg
    15781 ccattttgga aagtgctgat gatggttaac acccaatgtt gtgggagtag ctttccaatc
    15841 gcctgcatat aaggcggcgt aatactaagc ggccacaaac aacccgccag catagaggtt
    15901 ggcatcacaa tcagattagc caattgactg ctttgttgcg catttttaga aaccgcacca
    15961 atcattaagc caaagcctat agctaacaaa ctataaagaa agaaagtcaa caaaacaatg
    16021 gctgttggaa tgtaaaagct gacatttgct accctgagta atcccagcat aatcactatt
    16081 tgtatcgcaa aggcaacaat accaacacag acatagctca gcatgtattg aaggcttgat
    16141 agccttgata agactaagcg attgtagatt tgactggact tatcaagcaa gataccaccg
    16201 tacaagacac tggtgctgcc tagcattagg atcaataaaa agccagttgt tgtcgaggaa
    16261 acagacttac tttgggaacg atcagctagg gtgatttctt tgaccttgta ggatagcttc
    16321 gtgttatgag ctgaaatctt cttgaaaacc tcttgattgc ctgctgccgc atcaccaatg
    16381 atattgtaat tctccaagag ataattagcc tgcgccttaa accattctgt tatttgacta
    16441 tcagcaatcg aacgtagagc gatcttttga gtgtctcctt ttagaacctt ctcaccaaag
    16501 cccggctcaa tggtcagcac agcctccagt gtcttggcct ttaggtattg atcaatagcc
    16561 ttttcctcta gcctagtata tatctgatat tttttattgt gctttaattg cgacacaaac
    16621 tgcttggaaa cctgactctt atccttatct aagatcccaa tcttagcttg acttccccct
    16681 gtaaagctca aggacaaggc cagcattgtt gttagcatag gcaacaggat aaaggtgata
    16741 tagcttgttt ttttacgtct aattttgata aataaggctt taataaaagg aatcatgctg
    16801 ccacctgctt tctcattctg accaaagcaa agaggataaa ggctgttcct ataccaagat
    16861 taaccattaa ggtaaccggt atgggattgg actgcccacc aaaaataaga taaaacaaac
    16921 tatcattgac ccattttatc ggggaaatat tagacagctg attaatcaag gcgctattta
    16981 aggttgacaa aggaatatag cttcctccca aaaaggcaaa gacaggaatg actgcattag
    17041 acgctaccgt caaaaaggat tgatttctaa taccagtcgc aagcccgata ccgatggcaa
    17101 cagacaaata aactagcgag gccgtcacac cgataatctg ccagtcatta gtcccccaat
    17161 taacacgtaa cacaaatcgg gtaaagacat aaagaatggt tagctggact gctgttgcta
    17221 gcataccacc aattaatttt ccaagcaaaa tagcactatt tgagacccct gtcaaataaa
    17281 tgcggctagc caccccttgc tgacgatctg atagcaccag attcatcgct gacataatgc
    17341 tataaaaggt aatcatggta aacatggaaa tagcatagta atccgctgag ctcatgcctt
    17401 tactggtttg cacagagcta gaggcgatat agtctatttt tcttttcttg atgttgctaa
    17461 tggcttctgg ataaaggtta gcaatcgaat cataggtctt ggcgttatcc acatagatat
    17521 tgacaagcat attaatcaaa tcagcattct gttggttaat gctgttggtg gtcacctcaa
    17581 tgttttggtc gctcttaacc tctagagctg ccgtcaaggc gccctcgctg accttttgct
    17641 tagccttagc gatatccttg gtttctttag cttctaaatg aagctcttta tttaacagct
    17701 ttaaaaacgt gataaagttc ttttgatact ctgtttcctt gccctcaagc tgataacgaa
    17761 ccgtcaattt aggaacagta gctgctgtat taaagctgga cttaaaagca aagcttaaaa
    17821 tcagaatcat caagatagga aaaaccacca tcatcaacaa agcagtccga tccctaaaaa
    17881 tctgtaagct ttcttttttg attaaatgaa ataagatcat aacaacccct aatctcttag
    17941 cttcttacca gtcaaatgca ggaagatttc ttctaaattc aaatgcttat gcctaatctc
    18001 actaaaagca atatgagcat ctgtcagctg acgaacaacc gagccaatgt cttcatgttc
    18061 aatcaggaga actgcttcaa gctcgttatc catcagtctc caattgggct tattagagag
    18121 atcgattgct tggtcagctg cgactgtcac catgatttgc tttgtgaaat cagactcata
    18181 gcgtctttct agctcggcct gactgccctc ttcaatcacc tgaccatgat ccataatgta
    18241 aatgtaatca cataaggcct caacctcttc catgtagtgg gtcgtgtaaa taacagtagc
    18301 tccttgctca tttaacaagc gaatagactc taaaatatga ttacgagact gtgggtcaat
    18361 ccctaccgtc ggctcatcaa agatgattag cttaggagaa tgcaccaaag cacaggcaat
    18421 gtttaaccgt cttttcatac ctcctgaaaa ctggcttgga aactggcttg cctgtgattt
    18481 taaccctacg aactccaagc tttttaaaac ctgctccttg agctcacttc cctttaagcc
    18541 atagagagag ccgaaaagct caacattctc ataggctgtt aaatcaggat aaacagcaat
    18601 atcctgaggg acatagccaa tcttggaact aatttttcga atagatttat aagattgctg
    18661 taaaacagtc acttcgccag cattcaaagg gattaaccct aaaatagcat tgattaaggt
    18721 tgacttacca gcgccattag gccctaaaag gccgtagatt ctcccttcct caattgtcag
    18781 tgagacatga tctattgcct ttttgccgcc tcgatagacc ttgacaacat cttttaactc
    18841 tacaaaactc atatattatt ccttctttcc aactctaacg ctgctcttta aaactaatta
    18901 acagataagt taaggtcaat aaaagcgaac caatcaacca accatataat aaggctgctg
    18961 tcacacacca gacaccaatc acactaaaga ggcatagggc tagtagctgc tgtagccagc
    19021 ctgagtaacg acaggccttg accaaggcat agcccaaaac cacaagcgta agacctgcca
    19081 ctgaatcttt tcctaaaaag agacatagac ctaagtaaca aaaagcatca accagtgtga
    19141 caagacttaa caaaagaaag ctagctgctg ccctatctgg tttaaaggct agccaagtca
    19201 tttttcctaa gagcaggcga ctgtcctttt tcagcataag atcaaaaagc aagaccaaaa
    19261 ccaacagggt cagctctacc aaggctatgc tatacaatag cacataacaa atgatttccc
    19321 agccaaagga tacgcgaccc aaaaaggtca gcaaaccatc aagagctaaa gcatcagaaa
    19381 ataatagaca aacaagcact agaccaagct ggattagacc aagcaataga tcaagccatt
    19441 gctgatagga cattgccctg atgtgcctta aatgccatct gactaagcgc cgtcttttat
    19501 gacttgttag aaaaagggtc actaggatta aaaaggatag caatgctagt attatgatca
    19561 tcgtaccacc ttcttatgca ttgattgaag atgactcaag ccttcaaccc ataaattgcc
    19621 tccaacatga acaagcaaca ccagccataa gctctgacta acataataaa tacttccgta
    19681 aataagacca gtcagtattt tggcgtaaaa aatggatctg cccatcagga aatggtttag
    19741 ggcatagcac aggctggtga tcaacaagac aagagcaatt ggcaatcgcc attgaagcca
    19801 caagatgtta aaccaaatca aacgataggt gatttcctca cagcaggcca aaaccaaggg
    19861 atagcctatc tgtggccatt tttgtgtcgt tccgacaaat gataggacta agggaagcca
    19921 ctcttttttt tgccagcagc ggctaagatg taaaaaagca acctcaacaa agagcacaac
    19981 aaagctcaag ataaaaccaa tgatcaaaag acgaccatca ctatgaccta agggcgcttt
    20041 aataggaggt gacagcaggt aaatccctgt taagactagg gcataataaa ccagtacagc
    20101 tcttaaaaaa cctattagat taaagctata gctatcacga ccctggccaa aaatagcctg
    20161 cattgcgatc gaaggacaaa aggtagccat taaaaagcat aggttaaggc attgggtgta
    20221 caaaggcatt tgtcacacct ccaaactgtc tcatgcgtgg atgattagca aatggaaagg
    20281 caggaatgca catctcaaga agctcaggag tgaggacacg tgtcacgtac cagccttttt
    20341 ctgaggcctc aggaggagta atgtctaaaa agacagcatt aggacttact tttttagtgt
    20401 aggctagtag tgtctttaaa tcctcttttt tatctttccc agcatggttt gtcaggtcac
    20461 taagacgaac ctctcctgaa atcaagggct caaaggcctt ccatttaagc tcctgatcct
    20521 ttggatgagc atagtaaaag acgttactat ctaggtctaa aaacaaggga gagtcactct
    20581 cagcattttg tgttgacgtt ggattataaa acaaattata gtaatagcta tagctaatag
    20641 ctgaagcttc catgattcct cttaacaggg tatgcttagg atccaagccc gcctgaaccc
    20701 caaataagag ataaggacct tcattggact tgtttttaag gataatacca aaggtataaa
    20761 gcggattatc ttctccaaca gtcatgtcaa tagggataat ctcataaaga ctgtccttac
    20821 caagtctagc ctcttccaaa agagctagaa tttccggatc atcaataatc actctgggac
    20881 aaggcttttt agtatgccag ctaagcatca tagagtcgat ttgaatatac tcaatcaagc
    20941 tattacacat ggctgcttcc agcgttgtat gagaggctgt ccccgttgaa aagcctggaa
    21001 tgatgtgctt ttcgcctaca gcctgattgg tcttatagcc aacgcaaagc atttgggcag
    21061 gcacatacat ctccttatct tcaaaaaaca tcggacactt aacccagccc aagacatcgt
    21121 cttgcgtcac cattttatca cacatgatca tgtgcaaatc atggcaacgg tcaatttgtt
    21181 cctgcgtaaa aacctgcaaa tactctaagg gcatgacagg atccgtctgg ctcaattcct
    21241 tataagaagc ataaacaatc cggtctgata ataattcccc agcaataaca gtggcataac
    21301 gctcaatgct ttcacctaag tatttgatca aggcttcctc ataatgactg ccataaccaa
    21361 tgatatgata gctcacctga ctcagctcac caataaattg cttgtggtag tcaggcatct
    21421 gtcctgtcac actctttaag taaacatcat gaggatggtt acaaatagga acctgagatt
    21481 gatttaagat accagttcgg ttaccactaa ggccctttag cttatcaaga atatggttga
    21541 acgaagggta ataatgtagc atccttagac ctccttatga ctcttcttga aggagttttt
    21601 taacaatctc acgtgttgaa atctgttgat cctcatacct taattttgtc agagcccctt
    21661 gtgtctgaga attagacatt ttcaaaatat cctgcacctg aatctcaagc gttggcaaat
    21721 agacacttaa caaacgccct tcaaattttg agcttcctgt ttgagcaata ataaaggcct
    21781 cactgacaac cagattcatt aacacattta acaaaggtac ataagaggag ctaacaggct
    21841 gtgttggcgg caactgctga cttgcaaagc gctgataaag cgtgtgatcc tgtaaacgtg
    21901 ccagcaccct tctctccaag ctatcaaaat cagcactatg aggaggattt aaggtacaag
    21961 catggataaa cggcccatca acaaagccaa gcaccaattg ttttttcaag gccacactga
    22021 tttcattaag gtgacgcagc atcataatat tcaaccggcc ttgacaaata acaatactct
    22081 gatagtctgc gagcttctca gataagcact tcatgttgcg atggtgctcc agagcatcta
    22141 agcgagaggt aacatctgtt tcttgaatga gcatttttag ctcatcgcta gccacctgaa
    22201 ggtttaagtt caggtgcttg gccagcagct cagcagattc attgacatag cttgaatcac
    22261 tgataaataa gacaggtgca gtatccttag cctgtcctga ttcagctatg aaatgataat
    22321 tgcctgttaa gaccttcatg atattttctt caagagcata agcgtcttca agcatcaata
    22381 ggtcgttata atacaaggct gtgatgacct ctgacaattt tgcaaataag tcagactcta
    22441 gtgttttttc gtaggtatca gtatcaataa ctttcccgtt aaaccaatcg gagatgatac
    22501 tgtagtaggc ttcttttaag gcttgtggct cttgtgcaat gtctaaaaca gcttcattaa
    22561 aatcccatag gccttttcta aagcaaaacg tatcgtcaaa ttgcacaatg cgaacattgc
    22621 tatttaattg atatttcatt gagactcctt atttccaata atcgtcatgt gaatcacatg
    22681 ctgggtcaag ccatccaagc ctagcttttc ttggaggtat tccttattgt accctccaat
    22741 atcaacactt ccatatacca aagctgttga gaccaattga acattttgag caatctctcc
    22801 agcttcaata aaggcataag cagtagcttg atttccatat ttacgtgtgt ttttgatgta
    22861 ctgataaaca tagataagaa tgacattgca gttttcggca gtgatcggtc cgtattcggc
    22921 aaaggctcta atatcctcct gatcactaag atgatgacac ctcagcgcgt gctgataagg
    22981 aaggtattca taaaaaccgt ccttgagtgt ttctacgttt cttgcataga aaaataaggt
    23041 gatggggtac agacccccac cagaagcaca atttcttaag gctactgtct tagtcatgcc
    23101 ttctttgatg attgcctgag agctgacacc acaagcataa taaagcaaat cagccaaatc
    23161 ctgcaaaggc atctcctcat ctataaactg cctatgactt ctccggttgg tgatacaggt
    23221 tgatagggct gctgagacct tcttagcttt aggaagtgct atcgtgtttg ccctatcctc
    23281 aaaatagtca ctatttgaaa aggtggtcac tgcagaatcc gtaaaaaact cagccacact
    23341 ggtcttaaac cctaggtaat tgttattagc cttgtaattc atcaaaaacc gttggctaag
    23401 attgtctgtt tcatcaggca tcaaatgctg tgccacaagc tgttttgatg tttttaatac
    23461 cgtttgatga tgataggttg ataacgataa gtgattggta ttaaattcaa ataactgtcg
    23521 tgcttcttct cttgttaggt cactttggtt atccgaacgt tgtttttcct tagaaaaaaa
    23581 tggcataact gtcttcctgt aatatattaa taaataatag taattagcag gtaccgacta
    23641 gtacctgcta attactacaa gacgttgaca tcaagctgat tgtcttcgtc tcttgtcatg
    23701 taacacccct atccaacacc agctaacacc atcaattaca aactgtaacc ttagtcgcta
    23761 gcaaactaat gattgtgacc tagctattaa ctattaaata gaagtattaa agtttacgct
    23821 tttggctcag ctgcaccata attgttgttt atggtagtat tgccccatga agctgagacg
    23881 cagcaacaac aagaacagca acagcagcaa ccaccaggag caacttgagt tgtttctgct
    23941 acactagtag ctaaaatatt tgaagcaaat tgtaacataa tgcttacctc cttatatcgc
    24001 ctgatcggta aaacaaaaca ctgataagag ttaaatgaga atacctctca actgatagca
    24061 aaagcaatca tgagcaggta tccagcaaca caaggctagc tattttgtat cgcccttgtt
    24121 aaagtgacca ttcaattctt accaactata ttatattaaa attcaagaca tatgtaaata
    24181 ctttctttaa tattttctta caaaaatgtc attatttttc cagaaaggtt agcttattga
    24241 gcttgacaaa gtcttaagcc tatctcttta atggcattta taaactatc
//
LOCUS       DARYUW010000032        22985 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYUW010000032 DARYUW010000000
VERSION     DARYUW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22985
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            85..366
                     /locus_tag="TVW11_001173"
     CDS             85..366
                     /locus_tag="TVW11_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1365275.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TVW11_001174"
     CDS             complement(492..917)
                     /locus_tag="TVW11_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1365276.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TVW11_001175"
     CDS             complement(914..1318)
                     /locus_tag="TVW11_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1365277.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TVW11_001176"
     CDS             complement(1340..2119)
                     /locus_tag="TVW11_001176"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1365278.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TVW11_001177"
     CDS             complement(2116..3048)
                     /locus_tag="TVW11_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1365279.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TVW11_001178"
     CDS             complement(3326..3598)
                     /locus_tag="TVW11_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1365280.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TVW11_001179"
     CDS             complement(3662..4099)
                     /locus_tag="TVW11_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1365281.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TVW11_001180"
     CDS             complement(4086..6218)
                     /locus_tag="TVW11_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1365282.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TVW11_001181"
     CDS             complement(6386..6712)
                     /locus_tag="TVW11_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365283.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TVW11_001182"
     CDS             complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TVW11_001182"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1365284.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TVW11_001183"
     CDS             complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TVW11_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1365285.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TVW11_001184"
     CDS             complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TVW11_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1365286.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(9483..10355)
                     /locus_tag="TVW11_001185"
     CDS             complement(9483..10355)
                     /locus_tag="TVW11_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1365287.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(10514..11839)
                     /locus_tag="TVW11_001186"
     CDS             complement(10514..11839)
                     /locus_tag="TVW11_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1365288.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(11823..12545)
                     /locus_tag="TVW11_001187"
     CDS             complement(11823..12545)
                     /locus_tag="TVW11_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365289.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            12717..12872
                     /locus_tag="TVW11_001188"
     CDS             12717..12872
                     /locus_tag="TVW11_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365290.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            12913..13815
                     /locus_tag="TVW11_001189"
     CDS             12913..13815
                     /locus_tag="TVW11_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1365291.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            13815..14630
                     /locus_tag="TVW11_001190"
     CDS             13815..14630
                     /locus_tag="TVW11_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1365292.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(14815..16236)
                     /locus_tag="TVW11_001191"
     CDS             complement(14815..16236)
                     /locus_tag="TVW11_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1365293.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(16263..18125)
                     /locus_tag="TVW11_001192"
     CDS             complement(16263..18125)
                     /locus_tag="TVW11_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1365294.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(18130..18969)
                     /locus_tag="TVW11_001193"
     CDS             complement(18130..18969)
                     /locus_tag="TVW11_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1365295.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TVW11_001194"
     CDS             complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TVW11_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1365296.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(20715..21542)
                     /locus_tag="TVW11_001195"
     CDS             complement(20715..21542)
                     /locus_tag="TVW11_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1365297.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(21543..22340)
                     /locus_tag="TVW11_001196"
     CDS             complement(21543..22340)
                     /locus_tag="TVW11_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1365298.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
BASE COUNT         6608 a         5484 c         4356 g         6537 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttttatgt agttattata taatattaat aagattatag tttactaata
     6781 tatatatata tatatttcta ataccagtaa cctttgtctg aaaatagcta gatcgtgctt
     6841 atcaaagaaa gcaaaaaagc ttcactctac aggaagtaag agagaagctt ccacgctaat
     6901 aggatactga tctgacatca tcaaaacacc aattgaggag agatttagcc ctcattccaa
     6961 ttgctctttc atcgcctagt ccttttctta tccgaagcgt ccggaaatat aatcctctgt
     7021 acgcttgtcc tttggctttg taaatagttc agctgtatcg ccaaattcac aaatatctcc
     7081 tgtgaggaaa aaggctgttt tatctgacat gcgtgaagcc tgctgcatgt tgtgggtaac
     7141 gatgataatc gtgtaatcct gctttaattg ctgaaccaag tcctcaattt ttaaggtaga
     7201 aatgggatca agagcagagg taggctcgtc catgagcaac acatcaggtg ctacagcaag
     7261 cgctcttgca atgcaaagcc gctgctgctg tccacctgat agggacatgg cactcttttt
     7321 taagctgtct ttgacctcgt cccaaatggc tgctcctctc aaggactgct ctaccagctg
     7381 atctagagtt ttcttgtcct taaggccatg tgtcctagga ccataagcca cattatcata
     7441 aatagacatg gcaaatgggt tgggctgctg aaagaccata ccaacacgct tacgcagact
     7501 gttgaggttt attgctttag catagatgtc ttgattgtct aagagaacct ctccttcgat
     7561 acgacaggaa ggaatcaagt cattcatgcg atttagggtt tttaaaaagg ttgatttgcc
     7621 acagccagag ggacctatca gggctgtgat ctgattttct ggtatgtcaa tggagatatc
     7681 ctttaaggcc tgaaatgctc cataaaagac attaagctgc ttggttgaaa aagctcccat
     7741 tttagacgac tcctttcact aatcggcgtg ataataagct tgatagggca ttgatcagca
     7801 agacagttat gagtaagata acacccgttg cataagcttc cttgacatgt agcccttcgc
     7861 tagacagcat gtacatgtga agagctagtg agcgtcctga tgacatgagg ctggttggcg
     7921 tattggtaga ggtgcctagg gtatacatca gggctgctgt ctcacccaca acacgtccaa
     7981 tcgctaggat taccccggct agaataccag gcattgcagc cggcagcact attttaaaaa
     8041 tcgtccttag cttacctgct cctaagccaa ggctagcctg acgcaagtga tcactaacag
     8101 agaggagcgc ttcttctgtt gatcgaatga taactggcaa caccatgatt acagacgtca
     8161 gaatacctga taaaagagaa tattgcaggc cgaaaaaaac cacaaagaac agcatgccaa
     8221 aaagaccaaa aacaatcgaa ggaatccctg atagcgtatc agctgcaaga cgtattgccc
     8281 ttacccatag tgagtcctgc ttagcgtatt ccacaagata gaagccagca aagacaccaa
     8341 tgggcaaggc tagcactaag gtgcctaaaa ctagactaac agttgagata atcgacggca
     8401 ttagagaaac attgtcagag gtataggtcc atgaaaataa ggataacgac agactaggca
     8461 agccttttat cagcataaag gcaataatca aaaataagga gccaaaggtc aatagcgaca
     8521 aaagatagac cagggctttt agtaaatagt tagtcatgag ctgattttcc tttcacataa
     8581 gcaaagcaag cattaatgat gagaataaag ccaaagagga cagccgatgt tgcaatcaag
     8641 gcctctctat gctgaccaga agcatatgcc atctctagga caatatttgt cgtcatggtt
     8701 cttgtgccct caaataatcc tgatggcagc acaggctggt ttcctgctac caaaataact
     8761 gccatcgtct caccaatggc acgaccaaat cctaaaataa gagcggaaaa aaggccggat
     8821 ttggctgctg gcaggatcac tcgaaaaata ctcctttcat gactggctcc cagtgcaaga
     8881 ctagctgaat aataagcctt tggaacagct ctgatagcag actctgaaag actgataagc
     8941 gttggcaaaa tcatgattcc taagagcaag gaggcagtca gcacactcat gccattacca
     9001 gcaaagctcc taatccaagg cactagcact tgaagaccaa aaaagccata aacgatagac
     9061 ggaatggctg ccatcagatt aacagctgac tttaaaaagc catagcatgc tttaggacaa
     9121 tagtaaacca taaaaactga ggtcaatata cctgttggca caccaatcac cattgcacca
     9181 agtgtgatga caaaagaccc tgcaatcatc ggcaaaatac catagcttgc cggctgattt
     9241 gacggtgacc aatcatttcc tagcaaaaag gctctcatac catacttagc aataaaggga
     9301 aggccattac taaaaataaa gatacagatt aaacaaatag caataattgc catcgctgca
     9361 ctgagaaaga agataacttt aaaaaaatcc tctttaaagg cttgtttatt cactgatgat
     9421 cctttctaag aaaggaaagc aagaacaaaa cacctcttct ttgccttcct tctaatcgtt
     9481 ctttatttga ctttgtccca gcttgttagc ttgccgctaa agacatcagc cagcacatct
     9541 atgccaatat tacttacctt attgtccttg tgaacaatca ctacgatacc atcaagggca
     9601 atcgcatcat caattaagcc cttgctctcc tcagttgtta ggtcacgaga aaccataccg
     9661 atgtctgctg ttttttcctt gacggcggtg atacctgctg atgagccatt tgaggtaata
     9721 tcaatgctaa tggctggatt ttctttcttg tatgcttctg ctaatttttc catcaagggt
     9781 gaaactgagg ttgagcctac aattgacagc ttgcctgata agcccttact gctataggct
     9841 ggcgcgtctg tttttgcttc gatcaatcga ttgtctctaa caatctcctg cccctgcttt
     9901 gagtcaataa aggtgataaa atccttacca actcctgata ggtctgagga ccatacaata
     9961 ttaaagggac gctgcagagg gtatttcccc tctaaaatag tctcacgact agcctttacg
    10021 ccatttacct ttagggctgc aacgtcgcta tttaaggacc ctagcgagat gtagccaatg
    10081 gcacgactat ttcccttaac agaggagatg accccttctg tgctattttg gataatagct
    10141 gtttttgctg tttggtcaat ctctttgtca ccgtcctttt ttagaatgcc tgtcatttcg
    10201 gtaaaggctc cacgagtacc tgagccattt tctcgagaaa caaggtcaat cctgtctgct
    10261 gcttttccag catcagcact gttattgcca caggctgcaa gacctaagcc tgataagcca
    10321 atagctgcca tgatcagcat ttttttgatt gtcataagaa tcacccttat cttttatgat
    10381 attgtgttgt aggcttgcta cacctatagc ttatcaggtc tttgtaaagg tttatccctg
    10441 attaatgtaa agattttgta aaacctaaaa cagccactac caaggctggc cttaagtagc
    10501 tggtagtgac tgtttacttg ttgatagctt ctggtaagaa taaggtaaat tggctgccct
    10561 ctcctagctg acttgtgact gttatctgac cgccaagaag ctgactcagc tcctttacaa
    10621 tggctaggcc taggcctgtt ccaccacttt gcctgctacg tcccttgtta acacgataaa
    10681 agcgctcaaa aatacgatct agctcaattt ggctaatgcc aatcccagta tctgcaactg
    10741 taatggcaac accaccagca accctttgac tggatagctg aattctgccc ccattgtctg
    10801 tatactgtat cgcatttgat aagagattta acatgatctg cgataagagg tattgatcag
    10861 atgtcacaac aatcgaatcc tccaatgcat agcttagctc aagctgcttt tgctctagct
    10921 gtggtctcat gctctgacct gtatacagca ggaagttcct gagctgaaac tctgtcaggt
    10981 caagtggtgt cttgttagcc ttggataagg tcagcaggtg ctcaacaata cgttctagac
    11041 gcaagctttc attgtagata atgtctaaaa agtcttcttt taggcttgtt tcatcgtcag
    11101 gcatttcctt aatcgtttca gcaaagccct tgatcgatgt aaccggtgtt cttaattcgt
    11161 gagaagcatt agcaataaac tccaaattta gcctctcata atgacgaatg gccgtcagat
    11221 catataagag cactaaaatc tccttgacaa catgcgactg gttaaagata ggcacaaggg
    11281 taacctccaa gatcaaatca ccatcatgta ggcctgttaa ttccttcttt aatgtctgct
    11341 tttggtcaaa gacttgatta actaaggcta tcagatccat tcgtttaaga tcctccaaga
    11401 ccacaaaagg tggcttagcc tctggaaaat aagccggtaa ggatttgctg gtcagcaaca
    11461 gctccctttg attggagact aaaagcatgc ccatcgtgag atgagaggtt acagcctcca
    11521 cattttttga taaggctttt agccttgctt ccttttgtaa taggtcactt tttagctctg
    11581 tcagctgctt agcataagca cttaaatcag cctgccccac taggagaaaa tggtcactag
    11641 ctgtcaaaag atggtggtgc aaggctctga attcacgctc ccatctaaat agcatgctca
    11701 agacataaaa gctagctacg agaccagtac acagcactac tagagtcagc acctgatgcg
    11761 gcccttgcca aatcagacca agagcagcca gcaagcaaag ccctagcagc atgctcaaac
    11821 gcctaagatg tcctatcatt ctttagctcc ttaaatttgt agccatagcc gcgaatggtt
    11881 tgaatatact gaggcgcctt aggattgtcc tcgatttttt ctctgagctt gccaatatga
    11941 acgtctacca gacgtgtttc ttggccaaag tcataacccc agatacgctc taatagccgc
    12001 tcacgcgtca gggtcatatt agggtgcttc atgagataga gcagtagctc atattccttt
    12061 ggggttaacg gcaatagctc cttgtcctta tagacctcat gtcgctctgg gtacagacgc
    12121 aattgactca tcgtataaaa aggctcacga cgctcttcac catcaccaga aatctctgct
    12181 tcagtacgcc ttaaaatagc cttgacacgc gctaataatt ctctaggact aaagggcttg
    12241 gtcacataat catctgcccc cagctccaaa gccaaaacct tgtcaaattc atcactttta
    12301 gcagaaacca tcataattgg ggttttgctt cccttagcac gaagcctttt gcagacctcg
    12361 ataccgtcta attgcggcag cataatatct aacacaataa aatcataagg ttctctttca
    12421 gctaatgcca aggcagtacg gccatctgtt accatctctg tcacaaagcc ctccttggcc
    12481 aagtgataat ccagtagcct taagataggc tcctcatcat ctactaataa tactcgtttt
    12541 gtcatttcat agctcccatc agccacatta tatcatattt gtcagtcaat ctaatgacac
    12601 actgcttgac ggcctgaagc ctaaaatcaa tcagaagata aaaagatgtt ttagctttgg
    12661 ctttaccgtc aaatgattgt ataatagagc tatattgatt gaaagaaggt atacctatgg
    12721 caattactca taagaaaaat gaccagctcg aaaagatgat ggcaggcttt gcgtctatcc
    12781 cagattttga taagccttta gagcttaacc aagatggaaa gctagtcact gaaaaaccaa
    12841 agccacaagt caagacagct aagcaggact agcccttatt ggcgtcgtta acatatagaa
    12901 aggatacggt gaatgtcgct tttttcaaat ctgccaccca gcgtgcttca atggtttgcg
    12961 atttttctat ccattatcat tgaagccctg ccttttgtat ttttagggac tattttatct
    13021 ggctgtattg aggttttcgt cacgcctgat ttagttcaaa gatacctccc tcaaaataag
    13081 tggctaagaa ttttatttgg tacctttatt ggctttgttt ttccttcctg tgaatgtggt
    13141 atcattccta ttattaatcg ttttttagaa aagaaggtgc ctagctacac tgctgttccc
    13201 tttttagcaa ccgctccaat tattaatccg attgttttat ttgctaccta ctctgccttt
    13261 gggaattcgc tgcgctttct catgctaagg cttttaggcg ccattttagt ggctgtcagc
    13321 cttggcatca tgctagcctt cattgttgat gagaacattc tcaaggaatc aacccagccg
    13381 gtgcattgtc atacttacag tcacgaaagc ctgccaaaac ggctttactt ggcactggct
    13441 cacgctattg acgaattttt tgatacagga aggtatctag tctttgggac cctgattgct
    13501 tcagccatgc agatttatct gccaacaaag gtgctgacag cgatcggaca tagccctttg
    13561 acagccatct tagtcatgat gctcttagcc tttatcttat ctctttgcag tgaggctgac
    13621 gcctttattg gagcttcgtt attgtcaacc tttggagttg ctcctgtttt agcctttctc
    13681 ttaatcggcc ctatggttga catcaaaaac ctcatgatga tgctcaattc ctttaaggga
    13741 gcctttattg ttcaatttat cagtgtatca gctgtgatga ttaccatata ttgcttactt
    13801 gtgggggtgc tgtgatgatt cgctttttaa ttttagcagg ctattttgag ttgaccatgt
    13861 atctagagct atctggcaag ctaaatcaat atatcaatat tcgttacgct tacttagcct
    13921 atatttctat ggttctatcc tttatccttg cattggtgca gctatacact tggactaaaa
    13981 acatcaagct acacagtcat ttaaaaggta aggtcgctca gctgaccagt ccccttatcc
    14041 tggtctttcc tgttttggtt ggcttgttag tacctacagt cagcttggat tcgacgaccg
    14101 ttgccgccaa gggctatacc tttccattag ccgcaggcgc ttcaaaaaca ggggtcagtg
    14161 atgatggtac tactattcaa tacctaaagc cagacaccag cctgtacttt accaaatccg
    14221 cctatcaaaa ggaaatgctc aatgaactga aaaaatacca aggcaaatca gccatcacca
    14281 ttaccactga caattatatg gaggtaatgg aattaatcta cctttaccca gacgaattcg
    14341 ttgatcgtac gattcagtac actggctttg tctataatga gccaggacat gacagctatc
    14401 aattcctctt tagatttggg attatccatt gtatcgctga ttccggtgtg tatgggcttc
    14461 tgaccactgg taatcaagaa agctatgcca ataacacttg gctgaccgtc aagggccagc
    14521 tgcacatgga atatgacaag accctagagc agcagcttcc tgtccttcaa atcgaggaag
    14581 cacaccaagc cccagagcct gataaccctt atgtctatag ggtattttaa caagcattaa
    14641 gcctccacac ctatgacaca ggtctatgga ggctttttgt taggggacag tacaaagacg
    14701 taattgagtt cgttccattt aaatgaaatg gctaaaagcc gtatagcatc agccttttaa
    14761 aagacgtgtg ctatacggct ttgctattgt tggtaaagcc tttgaggcta ctttctagct
    14821 ctcctcagac aggctacgcc cattggtctc aatgaccctt tgataccaag caaaggattt
    14881 tttcttgtag cgtgtcaaat gaccactgcc atcatcatgt cggtcgacat aaataaagcc
    14941 ataacgctta cttagctgag cagtcgacat agaaacacaa tcaatacagc cccaggaggt
    15001 atagcccata atgtcaacac cgtcctcaat agccttagca acctgcaata aatgctgcct
    15061 catgtaatca atccgataat cgtcctgaac tgtccagtga ccatcctttg tctgtactag
    15121 cttatctttg gcgccaagcc cattttctac aataaagaga ggaatttggt acctatcata
    15181 gtaatcattc aaggttatgc gaaggccaat tggatcaatt tgccagcccc attccgaaga
    15241 gggcagatga ggattaacca agccacctaa aatattgccc tcccctcgtt gataatgatc
    15301 cgggtgatga gactgagtca cactcatgta atagctaaag gataaaaagt caaccgtatg
    15361 ctgcgccaaa agctcactgt cgcccggttc aaattgaatg tcaatgtgct gctccttaaa
    15421 aaaggatttg gcataggaag ggtattttcc tctgacctga atatctgaga acaggagatt
    15481 acgttgctca aactgcttcg cagctaaaat atccctcgga tcagaggtca ttggataggc
    15541 tggcatagcc aaaatcatac agcctatttt aaaagcaggg ttaatcaatc tagcaagcct
    15601 tgtcacacta gcagacgcta ctaattcatg gtgaatcgct tgataaagct cctgcggagt
    15661 cagcttttcc tttggtgtca tgatagcacc actggtaaaa ggcatatgca ggattgaatt
    15721 aacctcattg aaggttaacc aatacttaac cttgttcttg tagcgctgca tgacagttgt
    15781 cgcaaaacgt tcaaagaagc caaccatacg acggtcagtc cagccattat agaccttagc
    15841 tagatgcagt ggggtttcgt agtgagatag ggtcactaaa ggctctatgc catgtgctat
    15901 cagctcatca aacaaatcgt cataaaattg tagccctgct tcgttaggct ctgtctcatc
    15961 gccctgagga aaaatacgag accaagcaat tgatgtccgg aaaaccttaa agcccatttc
    16021 tgcaaagagc gccacgtcct ccttgtagcg gtgataaaaa tcgatggcct ctagcttcaa
    16081 attagctgct gttggctcag ctgtatagtc tcctaagccc ccttctggta aaacatcctg
    16141 aaccgacaag cctttgccat ctgttaaata agctccctca acctgattgg cagcaactgc
    16201 ccctccccac aagaaatcct ttggaaaaca aaccatatta tctcctcctt caattcatct
    16261 ctttagagaa taacgagagc aacatcatgc tgagtgatat gctccttgtt gtcattaaca
    16321 atgatttcga gctgctcaga gctattggtc accacaaatg gagtcactaa agaatagccc
    16381 ttagagccaa tcaattcaag atctatacgt agcagcggct gcccctgctt aacagtatca
    16441 ccagccttaa ccagctgctc aaagccctgt ccttttagct caaccgtatc aataccaaca
    16501 tgaattaaga cgtcaactcc cttggcgttc tttaaagcaa tagcatgctt tgttggaaaa
    16561 agggtgataa cctcgccatc aaatggggca tagacatatt cctcattagg taaaatagcc
    16621 agcccctctc ctaaaagctt agacgaaaag gtttcatctg gcacctctga taatggaagc
    16681 actgtgccaa ccatcggagc ataaatagat tgctttgctg ataagccact ttttactggc
    16741 gtgctatccg agtcagctga cccctcctgg tcaacctcct catcaatgcc aaaaaaccag
    16801 gttaatgtaa aggttagagc aattgttaag cccgctgcaa ttaaggcatt ggtaaaatta
    16861 gcagagctag tcgggctaat gtattgtggc aatccaatta gtgatggcac cacaaaagta
    16921 taagaggcta tattaacaaa gccaatatag gcgcccacaa ggccaccaga aatcattgca
    16981 gcatagagcg gctttttaaa ctttagagta atgccataaa gagcaggctc tgtaattcct
    17041 gccaataaag ctgataagcc tgctgctaag gcaacctgac gggtttgctt ttgctttgat
    17101 tgacatgcta cagccaccgc tgctgatccc tgagctaggt tagaggctag cattgctggg
    17161 aggattaaaa catctggagt tgctacagag gccgccagaa aaataggagc aaaggcccaa
    17221 tgcatacccg tcataacaac aagcggcata attgcaccta aaatagcaag agccagccaa
    17281 ggagcaatat ggtaaatcgc tagcaggcta ttagacaagc cctgtcctat aataacaccc
    17341 agaggtccaa taacaactaa ggctagaaag cctgaaataa aaataatcaa ggtcggctgc
    17401 aggaagctct tcatcacact cggtacaaaa cggttaacct ctcgctcaat gtattgcatc
    17461 aggtaaacca taattaaaat cggaataact gacgcaccat agctagcagg tgtcaccggc
    17521 gctccaaaca aagccatagg tttacctgta gctaccatcg taacaaaagc tgggtgtagt
    17581 aaaatccctg caacagttgc tgctaataca ggtgtgacct taaagcgtgc cgcagctgaa
    17641 tatgcaatca tgattggcat aaaataataa gcagcatctc caaaaaaatt aataaaagca
    17701 actgtttgag agtccgtacc tgctagacca agcataggca ccaagatccc aaccaccttt
    17761 aacataccgc ctcccagtaa ggcaggtatc agtggagtaa tcacactagc tatcgtttca
    17821 atcaaccctt caatcataga ctgcttttga ccagcgctag agctcatatc agtttcatga
    17881 aactgtccta gggtcataaa tgccttataa taattgttaa catcgtttcc taaaataatt
    17941 tgatactgac cgttttggcg catgactcca atcacattag gaataagttt gattttttga
    18001 tctaccactt gtttatcatc tttcaaaacc aagcgtaacc gcgtgatgca gtgggttacc
    18061 tcttgaatat tctgctcacc accaactgct tcaaaaatgg ccttggctgt ttcttgataa
    18121 gtcatttcat tactccttca catttttgac taaacgtttg atatgaaccg ttaaatacaa
    18181 aagctcacta gagctaagct gataatggta tgcttttttc atgtgatggc taatttgcct
    18241 aacacagtga tattcctctg ggtatttatc cttaaccatc agcagcaaat cagtctcgtc
    18301 atcatcataa gccatgcctg ataacacgcg ctgagcaaat agcttcacat gagtgataaa
    18361 gcgataataa tcaatagaga cttcatcaag ctctgtctta aaatcagcct tgaccttctg
    18421 ttcaatgtaa gacacaattt ctgtcattcg atgaggctcc ttgaaaggat tatcaaggct
    18481 cgcgttgaca aagtgcatcg caataaacga agcttcatct acagccagag cgactcctag
    18541 ctcactggca atgacctcta aggccttaac gccaatcgca tattcatcag gataataccg
    18601 tctaatctcc cagcgcaagg gatcactaat gatcatcccc tgcttatgtc tttcaatagc
    18661 tgaatgaata tggtctgtca aattgatata gagtatttca tctaaatttt tacccagctt
    18721 aattttccct agattaataa gcctctctga gcaagcaacc acctcttgcg gaacagcaat
    18781 aaataattca gtaaaacggt tcatattgtc actatttttt aaaacaaatg acgcttcgat
    18841 agcttcacta tcgatatggt caccaattct tttcttaaaa gcaatcccct ttcccatcaa
    18901 aagaatatct agcccctgat ggttggtcga aatcgctgca ttatggttta aaacgcgttt
    18961 aataatcata aaagtcctag tccctcattg cttcacaata aaaaatgacc tatccacagc
    19021 atgctaaaag gccacactgg aataggtccc tgctcacaaa actgtgataa catcctttaa
    19081 tattctgatt catttgtcat tagcacgctt accctaagta atcacatcta ataacgtttt
    19141 cattttatca tctcctaaag gtcctgtcaa gcgttttcaa aaggctgttt gacatttgcc
    19201 tctaaacgaa ccccctcatt ctctttggcc aacagccgat aatctgaggc tttcctctta
    19261 aagtatgcct tctaatagtc ccttcataaa gtcctcagag tgaaattcac cgatatcatc
    19321 aatagcctca ccaaagccaa tcagcttcac tgggatatcc aattcctgac gaatagctag
    19381 gacaattccc cccttagctg taccgtcaat cttagttaaa atcaagcctg tgagcggtgt
    19441 gatttttgaa aactccttag cctgactcag agcattttgc cccgttgagg catcgagcgc
    19501 tagcagggtt tcgtgtgggg catcaggtat gacacgctta atgattcgtc ctattttttc
    19561 aagctctgcc attaggttgt ccttattttg caggcggcct gcggtatcaa tcaggagaat
    19621 atctgccctt tcagcaacag ccctctcaac gccatcaaag accacagagg ccggatctgc
    19681 tttttcaggg cctgtaatga ccggcacatc aacccgtcgt ccccattcaa ccagctgggc
    19741 aaccgcgcct gctcggaagg tatcagctgc aacaagcata accttttttc cctcttgctt
    19801 ataccgataa gctagctttc caattgatgt tgtcttacca acgccattca ccccaacaaa
    19861 gagcataacg gtcaagccag gctgataatg aatcgcttca ttgtagcggc catccccctc
    19921 ataaatagcc actagcttat caatgataag acgctttaga gcctctggct ttttagcatt
    19981 ttcaagctta gcctcatagc gcaattcttc agtcaaggtt gtggcaacat gaacaccaac
    20041 atctgagaga atcaaaagct cctctaagtc ctcaaagaag tcctcgtcaa cacgtctaaa
    20101 gttagcaaag aagctgttca agcgtgctga aaagcctgta cgggttttct ttaagctgcg
    20161 cttgtatttt tcctgatcag attcagctga tagggtctct tgcttttggc cttcctcagc
    20221 tggctgatca gctgaaccag caggtgcttg agctgctact tgatactcag catttgtctc
    20281 tgcctgatct tctgttgatg cgtctgcgct ctcgttacta tgctctgact tagccctatc
    20341 atgcttagcc tcctccatag cctcgtgctg gcttaggctc tcacctgcct gatccaaggt
    20401 cttgtcatca gtagctgcta actctagctc cggctctctt tctaaaagaa aagctcctct
    20461 agctgctgga tcaagccctt cagcttgctc tgaagcagcc tcgtctgaga gctcagcctg
    20521 tttgctagtg tcatcggtcc tagagaccac atcagctgcc actgcatgag catttgtatc
    20581 tgataaggcc tccttttcag actcaatcgt atcctttgac gttatgtcct ccgacaatac
    20641 ctctgtagtg gcagcctctt gctcagcaac cttagtctta tccttttttc caaataagcg
    20701 ttcaaataat cccattagcc ttcctcattt aaaatatatt tccaaatagc ctcagccaca
    20761 cctgattggt cattggttag ggtagtcact gcatctgcca cttccttagc ctgatcaacc
    20821 gcattggcca tagccacacc aagacctgcc cattgtagca tgctaaagtc attggcctca
    20881 tctcccatcg ccatgacatg cttggcctcc aagcccaagt gctgacaaag caggtccaaa
    20941 ccaaatgcct tatgaatccc cttaggcata atctcaaaga tgatgtctcg tgatttaaag
    21001 gcctcaaaat cctcaaagat agtctttgga agccttgcaa gctgctgatc caagaccttt
    21061 ggatccgtca ccgtaacaat tttattgtat gtgatgtcct ttggcagctc agcaaatgat
    21121 ttaaggctaa caaagttcag caagggactt gccaagtgat actgagagcg tctgccatca
    21181 ttgcctgata gactataaac agtaccatca ctgataacat cagtaggtaa gccaaccgct
    21241 gccaactgct gatgaatgtc ataaacctca gcaaggctta gagcgctttt atctaaaata
    21301 tgaccagtat ttcgttgaac cagaccgcca ttaaaggtaa tgctatagtt ctcttcacct
    21361 agcaaatcca gctcctcaag caaatttccg atagccttaa gaggacgtcc ggttgtgata
    21421 acaaccttaa ctcctttttc cttagctgct gctagagctt ttttgttctc atcactaacg
    21481 attttttcgg tattatagag agtcccatct aaatctagag ctaaaagctt tatacgcgtc
    21541 atttacacca atccctccaa ataagttaac actgctgagt cattacaatg accaataacc
    21601 tgatcagaaa tcgctttgat ttcaggcctt gcattttcag tagcaatagc ctgccctgca
    21661 aaggacagca tttgataatc atttagatta tcgccaaagg caatggtctt ttccggtaaa
    21721 atgcctaggt gctgacacag ctgatccatg ccaaagccct tatgaacctc ttttaggata
    21781 atatcaatcg aatcaaagcc agtcgtcacc gcagaagcat aggacagctc ctgatttagc
    21841 cagtcactgc cagctaagac tgtttctcct gtaaaggtcg ttgaggcttt aaaaacagtg
    21901 tcatcaacaa tatcctgcag acaatcaata agctgaacat tttcataata ataatgcatt
    21961 ttttggatat aatcctccgt agctcctttg agcacatagg ctgccttttg ccctgaaaag
    22021 aggatcccag actgattgta ataaggattg gcaagaattt tctctacaat gtcatgacac
    22081 tgctgcttgg tcatgacatc agcaaaaaga atgtccctct tgtattgcac cacagaccca
    22141 ttctcagcga taatggcaat gtcatctaaa aaaggctcaa acaagtgatc aatggctaaa
    22201 agcgaacgcc cactagaaac tgtaaagaga atcccttttt ctcttagctt aggcaacaga
    22261 gctgccaagc gctccttgtc ataagttccg tcctctctta aaaaggttcc gtccatatct
    22321 gttgctatca atttaaccat acaatttaac catttccttt ttagggagat actgattcag
    22381 ctattcagct ctcccaaaaa tctctttttc cattatacca tatctaaaca aaaagggcgt
    22441 gcctgtccta acacgtcctt gttttaaggc tttataattt ctgtagtggg taactccact
    22501 gtggagatta ttgagccctt attccaaggc tttctttatg ttctattgta tcaatttcct
    22561 tattccaatt tctgttgcaa ttaactttaa catacaatct aaccatttca ctttcaaggg
    22621 agtgcaaaac ccgagtgggg tgtgcaactc aaatcccagt ataactcctt tcgttatacc
    22681 acaggtagac caaaaaaggg cgtgccatct gacataccct tgttttaaca gtcaatctga
    22741 gctccgtttt taaaggctaa acttctttat ctccatactc tcaacgctta tttgccataa
    22801 ttcttaattg aagcccgtca ctaagttttc ttgttactaa agagttgagt aatgaatcta
    22861 tctagactga tgatttttct ccttaaaagc ttcatatagt tttttatata acgctttctt
    22921 ttcttttttc tgagcattaa actctttttt accgtaatca aaatttgcta ccacaaaccc
    22981 cttgt
//
LOCUS       DARYUW010000033        22573 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYUW010000033 DARYUW010000000
VERSION     DARYUW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22573
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            380..1864
                     /locus_tag="TVW11_001197"
     CDS             380..1864
                     /locus_tag="TVW11_001197"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1365299.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            1904..3205
                     /locus_tag="TVW11_001198"
     CDS             1904..3205
                     /locus_tag="TVW11_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1365300.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3585..3893
                     /gene="rpsJ"
                     /locus_tag="TVW11_001199"
     CDS             3585..3893
                     /gene="rpsJ"
                     /locus_tag="TVW11_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1365301.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPFPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4191..4817
                     /gene="rplC"
                     /locus_tag="TVW11_001200"
     CDS             4191..4817
                     /gene="rplC"
                     /locus_tag="TVW11_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1365302.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4842..5465
                     /gene="rplD"
                     /locus_tag="TVW11_001201"
     CDS             4842..5465
                     /gene="rplD"
                     /locus_tag="TVW11_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1365303.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5465..5761
                     /locus_tag="TVW11_001202"
     CDS             5465..5761
                     /locus_tag="TVW11_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1365304.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5779..6612
                     /gene="rplB"
                     /locus_tag="TVW11_001203"
     CDS             5779..6612
                     /gene="rplB"
                     /locus_tag="TVW11_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1365305.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6724..7002
                     /gene="rpsS"
                     /locus_tag="TVW11_001204"
     CDS             6724..7002
                     /gene="rpsS"
                     /locus_tag="TVW11_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1365306.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7018..7362
                     /gene="rplV"
                     /locus_tag="TVW11_001205"
     CDS             7018..7362
                     /gene="rplV"
                     /locus_tag="TVW11_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1365307.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7375..8028
                     /gene="rpsC"
                     /locus_tag="TVW11_001206"
     CDS             7375..8028
                     /gene="rpsC"
                     /locus_tag="TVW11_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1365308.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8032..8445
                     /gene="rplP"
                     /locus_tag="TVW11_001207"
     CDS             8032..8445
                     /gene="rplP"
                     /locus_tag="TVW11_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1365309.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8455..8661
                     /locus_tag="TVW11_001208"
     CDS             8455..8661
                     /locus_tag="TVW11_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1365310.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8686..8949
                     /gene="rpsQ"
                     /locus_tag="TVW11_001209"
     CDS             8686..8949
                     /gene="rpsQ"
                     /locus_tag="TVW11_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1365311.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            8974..9342
                     /gene="rplN"
                     /locus_tag="TVW11_001210"
     CDS             8974..9342
                     /gene="rplN"
                     /locus_tag="TVW11_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1365312.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9426..9731
                     /gene="rplX"
                     /locus_tag="TVW11_001211"
     CDS             9426..9731
                     /gene="rplX"
                     /locus_tag="TVW11_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1365313.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9755..10297
                     /gene="rplE"
                     /locus_tag="TVW11_001212"
     CDS             9755..10297
                     /gene="rplE"
                     /locus_tag="TVW11_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1365314.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10313..10498
                     /locus_tag="TVW11_001213"
     CDS             10313..10498
                     /locus_tag="TVW11_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1365315.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10831..11229
                     /gene="rpsH"
                     /locus_tag="TVW11_001214"
     CDS             10831..11229
                     /gene="rpsH"
                     /locus_tag="TVW11_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1365316.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11551..12087
                     /gene="rplF"
                     /locus_tag="TVW11_001215"
     CDS             11551..12087
                     /gene="rplF"
                     /locus_tag="TVW11_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1365317.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTSRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12190..12546
                     /gene="rplR"
                     /locus_tag="TVW11_001216"
     CDS             12190..12546
                     /gene="rplR"
                     /locus_tag="TVW11_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1365318.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12565..13059
                     /gene="rpsE"
                     /locus_tag="TVW11_001217"
     CDS             12565..13059
                     /gene="rpsE"
                     /locus_tag="TVW11_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1365319.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13074..13256
                     /gene="rpmD"
                     /locus_tag="TVW11_001218"
     CDS             13074..13256
                     /gene="rpmD"
                     /locus_tag="TVW11_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1365320.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13458..13898
                     /gene="rplO"
                     /locus_tag="TVW11_001219"
     CDS             13458..13898
                     /gene="rplO"
                     /locus_tag="TVW11_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1365321.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            13915..15219
                     /gene="secY"
                     /locus_tag="TVW11_001220"
     CDS             13915..15219
                     /gene="secY"
                     /locus_tag="TVW11_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1365322.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15371..16012
                     /locus_tag="TVW11_001221"
     CDS             15371..16012
                     /locus_tag="TVW11_001221"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1365323.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16130..16348
                     /gene="infA"
                     /locus_tag="TVW11_001222"
     CDS             16130..16348
                     /gene="infA"
                     /locus_tag="TVW11_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1365324.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16374..16490
                     /gene="rpmJ"
                     /locus_tag="TVW11_001223"
     CDS             16374..16490
                     /gene="rpmJ"
                     /locus_tag="TVW11_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1365325.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16508..16873
                     /gene="rpsM"
                     /locus_tag="TVW11_001224"
     CDS             16508..16873
                     /gene="rpsM"
                     /locus_tag="TVW11_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1365326.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            16891..17274
                     /gene="rpsK"
                     /locus_tag="TVW11_001225"
     CDS             16891..17274
                     /gene="rpsK"
                     /locus_tag="TVW11_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1365327.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17321..18259
                     /locus_tag="TVW11_001226"
     CDS             17321..18259
                     /locus_tag="TVW11_001226"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1365328.1"
                     /translation="MIECEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18274..18660
                     /gene="rplQ"
                     /locus_tag="TVW11_001227"
     CDS             18274..18660
                     /gene="rplQ"
                     /locus_tag="TVW11_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1365329.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(18878..19109)
                     /locus_tag="TVW11_001228"
                     /pseudo
     CDS             complement(18878..19109)
                     /locus_tag="TVW11_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            19965..21215
                     /locus_tag="TVW11_001229"
     CDS             19965..21215
                     /locus_tag="TVW11_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365330.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21205..22080
                     /locus_tag="TVW11_001230"
                     /pseudo
     CDS             21205..22080
                     /locus_tag="TVW11_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22101..22394
                     /locus_tag="TVW11_001231"
     CDS             22101..22394
                     /locus_tag="TVW11_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1365331.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         6951 a         4056 c         5021 g         6545 t
ORIGIN      
        1 tttttagttt agaagctttg agtttagacc tcaaaactta gatatggaat tcgaaaggca
       61 gtcactgctg tcaacattac tttgggaaag ttcctataag agacttttca ttagactgaa
      121 gtagcttcaa tagctctaaa actacctaga ctcaagtaac aacaagtcct tagaattgat
      181 tttctaaggg cttttttgct gcctcaaggt aaagacatgt tcagcaacaa attgactggc
      241 tagaccagtc ctttatttat gctgatggct tgagactgct gggttattag cacagaaaat
      301 ggctgtctcc aaatcctaga aggcttatga ttggaatatg atataatagt caaaagaaat
      361 gatgaggtga tgtgaagcaa tgccaatgat gtaccaatca acaagaaatg cagctaataa
      421 ggtaacagct agtcaagcga ttttaagtgg cctagcagat gatggtggct tgtttactcc
      481 tacaagcatg ccagtgctgg atctagattt tgaggagcta aagaccaagt cctatcaaga
      541 ggttgccaag cttattttat cagccttttt tgatgactat actgaagcag aattagatgc
      601 ttgtatctct tctgcctatg atgataagtt tgatacagca gtgatagcac ctctagctac
      661 gttaaaggat tatcataatt tggagctatt tcatggctca accatcgcat ttaaggacat
      721 ggctctatct attttgcctt atctcttgac aactgctgct aaaaagcaag gtgtggagcg
      781 aaaaattgcg attttaaccg ctacctcagg tgatactggt aaggcagcaa tggcaggctt
      841 tgttgatgtt ccgggaacgg atattattgt cttttatcct aagtcaggcg ttagcaggat
      901 tcaggagctg cagatgatca cacaggccgg tcacaatacc catgttgtgg cgattgaagg
      961 caattttgat gatgctcaaa cagaggtcaa gcgcctgttt aatgaccctg atttgcgtga
     1021 gcggctagca gctcaacaga tacagctgtc ttcggccaat tcgatgaata ttggtcgttt
     1081 gattcctcag gttgtctatt atatttatgc ttatgcccag ttggtaaggc atcagcgact
     1141 tgaagctgga gagacgatta acatagtagt gccgacagga aattttggca atctactggt
     1201 tgcctactac gccaaagaaa ttggacttcc tgttgccaaa ttcatctgtg cttccaatga
     1261 aaacaatgtc ttgacagatt tctttgctag tggtaggtat gataaaaagc gtcccttcaa
     1321 ggtgactact agtccatcaa tggatatttt ggtgtcttca aatttagagc gcttggtttt
     1381 ttatttacta ggcaatgatg cccaaaagac agcagtatta atgaagagct tggcagaaac
     1441 aggtcagtat cagctagctg atgcagatca gtctatcctt gatttatttg cggcaggctt
     1501 tgcaacagag caagagactg ctaaagagat caaaacgata tttgagtctg atcattatgt
     1561 gcttgaccca catacagctg tagcttcagc tgtttatcgt gcttatcggg agcaatcagg
     1621 tgactctaga ccgactattg ttgcgtcaac tgctagtcct tataagtttc cgcgggtagt
     1681 tgtggaagct attagtggtc agcaggttgc cagtgatttt gaggcgcttg agcagttggc
     1741 tgatatatca ggtgtagtcg tgccacaagc ggtcaatggc ttacaggagg cgcccattcg
     1801 tcatagcctt ttagtgacag tagcagatat gcagcaggca gtagaggctt atcttggagt
     1861 ataggaggca taaaggagct ccctttcaat tgatatgaat ataatgactc acaatagaaa
     1921 aaagatactg tccttggccc ttccatcaat ggcagaaaat atattgcaaa tgctgatggg
     1981 aatgatagac aattatttgg ctgctcaaat tggacttacg gctgtttcag gcattgcgat
     2041 tgctaataat attctgacga tttatcaggc cctttttatc gcattaggtg ctgcagtctc
     2101 cagtctcatt gctagaagcg taggagagca aaaccattct aaagaaatcg actacatggc
     2161 aaatgctatc ttagtaacgg gggctctatc agttcttcta ggcttgatgt ccgtagtggg
     2221 acataaaagc atattagcct ttctgggagc agctagtctg gtagctagac ttggtgggca
     2281 gtatttagcc attgtcggtg gaatgattct tagtcttggt cttttcacga gcttaggtgc
     2341 gattattcgt gctaagggcc agcctagcat tcccatgaag gtcagccttt taactaattt
     2401 gctaaacgct gtattttcag ccctttctct ttacatatgg ggatttggag tgatagggat
     2461 tgcttggtca actgttgcat cacgtctcat tggagttgtt attctatgtc actttcttcc
     2521 tattaaagaa attattaaac gttttgctaa tcccttagat aaagagatct ttagcctctc
     2581 tcttccagcg gctggtgagc ggctcatgat gcgagctggt gatgtgctga ttgttactat
     2641 tattgttaga tttggaacag aggccttggc aggcaatgcg attggagaaa ccttaactca
     2701 atttaattat atgccgggac ttgctatgtc aactgcgaca gtcattttag ttgccaatca
     2761 gttgggcagt ggcaaagggg ctacaatagc gaaaactgta aaagaaacct ttttgttagc
     2821 caccctgatg atgcttgtta tgggcttgat cacttatttg ctaggcccta atctactgcc
     2881 cttatttaca gcagatgcca aggctcagca ggctggtatg gttgtcttag tcttttctct
     2941 tttgggggta ccagcaacag ccgggacctt ggtttataca gcagcctggc agggtatcgg
     3001 acaagctaag cttccctttt atgcaacaac gattggtatg tggctggttc ggatttcttt
     3061 gggctacttt attggagtaa ccttaaatta tggagtaata ggtgtttggc ttgcgactat
     3121 tttggacaat gctaccagat ggctcattct tgcagtggct tttaagaagc agcaaaggca
     3181 gcttttttcg gactgtcata gctaaacttt gtatttaggt ctcaagactt ctgagtggtg
     3241 actttccttt tgggagtcag ccactgtcat cagaatgtaa agtacgcctg aggctctgtt
     3301 tgctaatagc ttctcttatc tgcggaagat caaagaggat tgctggaaca gctgaggttt
     3361 gtcttcaatc tggcttgccc tttcttaggg caagtttttt tgaaaaaatc ccctgaaagg
     3421 cttgcaatgc cttattaatt ctgctattat attatggtgc tgtaaaaata cagctttagc
     3481 tgtgatacga gaggttgcga cacgctcggt tgcattgcca cgtgacaggt gtcggttttc
     3541 tcgaggagct agcctattat cgtaaataga cgagaggaga aaagatggca aacaaaaaaa
     3601 tccgtatccg cttgaaagcg tacgaacacc gtacacttga tacagcggca gaaaaaatcg
     3661 ttgaaactgc aactcgtaca ggtgcaacag tagctggacc agttccattt ccaactgaac
     3721 gtagtcttta caccattatt cgtgcgactc acaagtataa agattctcgc gaacaatttg
     3781 aaatgcgtac acacaaacgt cttattgata ttgtgaaccc aacgcaaaag actgttgatg
     3841 cacttatgaa attggacctt ccaagtggtg tcaacgtaga aatcaagctt taattgtttg
     3901 aaacatgagt gaggaacgag ttcatatcta attgaacaca ggctaaactc tgtgtgaaaa
     3961 agagacacag ccgttctaat tttaattaga ttacggatgt ggctacctgt aggtgtaaat
     4021 cttcctagaa acagaagttt cttcgtcaga tttcctattt tcactgtgag tttgacgcct
     4081 taagtatctt gctttgagca taaaaaacgc tcgtaaaaaa cttttttgag cataaaaaac
     4141 gctcactaaa aactttttga aatattatta agaaaaggaa ttattttctc atgacaaaag
     4201 gaatcttagg ggaaaaagtg ggaatgactc aaatcttcac tgaatccggt gaatttatcc
     4261 ctgttactgt catcgaagca actccaaacg ttgtgcttca agttaagact gttgaaacag
     4321 acggttacga agcaattcaa gttggttttg atgataaacg tgaagtattg agcaacaaac
     4381 ctgccaaagg ccatgtagca aaagctaaca cagctcctaa gcgcttcatt cgtgaattca
     4441 aaaacattga aggcttagaa gtaggtgcag aaatcactgt ggatatcttc gcagctgggg
     4501 atgttgttga tgtaactggt acttcaaaag gtaaaggctt ccaaggtgtt atcaaacgcc
     4561 atggtcaatc acgtggtccg atggcccatg gttctcgtta ccatcgtcgt ccaggttcta
     4621 tgggacctgt ttcaccaaac cgcgttttca aaaacaaaca tttggcagga cgcatgggtg
     4681 gcaatcgtgt aactattcaa aatcttgaaa ttgtacaagt tatcccagaa aagaacgtta
     4741 ttcttattaa aggtaacgta ccaggtgcta agaaatctct tatcaccatc aaatcagcag
     4801 ttaaagctgc taaataataa gaaaggagaa aacagttaaa aatggcaaac gtaaaactat
     4861 ttgaccaaac tggtaaagaa gttagcacag ttgaattaaa tgatgatatc tttggtatcg
     4921 aaccaaacga atcagttgtt tttgatgttg taatcagcca acgtgctagc cttcgccaag
     4981 gtactcatgc ggttaaaaac cgttcagcag tatcaggtgg tggacgtaaa ccttggcgtc
     5041 aaaaaggaac tggacgtgct cgtcaaggtt ctatccgctc accacaatgg cgtggtggtg
     5101 gtgttgtctt tggaccaact ccacgttcat atggatacaa acttccacaa aaagttcgtc
     5161 gccttgcttt gaaatcagtt tactcagcaa aagttgctga agataaattt gtagctgtag
     5221 aaagcctttc atttgcagca ccaaaaacag ctgaatttgc aaaggtgctt tcagctctta
     5281 gcattgatac aaaagtactt gttcttgttg aagaaggaaa tgaatttgca gcactttctg
     5341 cacgtaacct tccaaacgta gctgtggcaa cagcagcgac tgcaagtgtt cttgatatcg
     5401 taaacgcaga caaacttctt gtaacgaaag aagcaatctc tacaattgag gaggttcttg
     5461 cataatgaat ttgtacgacg taatcaaaaa accagttatt actgaaaaat caatgtatgc
     5521 ccttgaagaa ggtaaataca catttgaagt tgacacacgt gcgcacaaac tgttaatcaa
     5581 gcaagctgtt gaagctgcat ttgacggagt taaggttgca agcgtcaata ctgttaacgt
     5641 taaaccaaag gctaagcgtg ttggtcgtta cacaggtttt acttcaaaaa ctaaaaaggc
     5701 tatcatcact cttacagctg attctaaagc aatcgagttg ttcgcagttg aagctgaata
     5761 atctaaggag gaaataacgt gggtattaaa gtttataaac caacgacaaa tggccgtcgt
     5821 aacatgactt ctttggattt cgctgaaatc acaacaagca cacctgagaa atcattgctt
     5881 gtttctctta aaaacaaagc tggtcgtaac aacaatggtc gcattacagt tcgtcaccaa
     5941 ggtggtggac acaaacgcca ttaccgtttg attgacttca agcgtaacaa agatggtgtt
     6001 gaagcagttg ttaaaacaat cgaatacgat ccaaaccgta ctgcaaacat tgcacttgta
     6061 cattacactg acggagttaa ggcttacatc atcgctccta agggtcttga agtaggtcaa
     6121 cgtattgttt ctggaccaga tgcagatatt aaggttggta atgcacttcc attagtaaac
     6181 attcctgttg gtacagttgt tcacaacatt gagcttaagc ctggtaaggg tggagagctt
     6241 gtacgtgctg ctggagcttc tgctcaagta cttggtcaag aaggcaaata cgttcttgtt
     6301 cgtcttcaat caggtgaagt tcgtatgatt cttggaacat gtcgtgcaac tgttggtaca
     6361 gttggtaacg agcaacaatc acttgttaac attggtaaag caggacgtag ccgttggaaa
     6421 ggtatccgcc caacagttcg tggttctgta atgaacccta acgatcaccc acatggtggt
     6481 ggtgaaggta aagcaccagt tggacgtaaa gcgccatcta ctccttgggg taaaccagcg
     6541 cttggtctta aaacacgtaa caaaaaagct aaatctaaca agcttcttgt tcgtcgtcgt
     6601 aacgaaaaat aagcggcaaa tctagcataa gcttattcaa tcattccgcc agctcggtag
     6661 agtttgagct tgctctcatg ctcaagccgc tgtggtacat tatttaaagg agaaaactac
     6721 aaaatgggac gtagtcttaa aaaaggacct ttcgtcgatg agcatttgat gaaaaaagtt
     6781 gaagctcaag ctaatgacga aaagaaaaaa gtaatcaaaa cttggtcacg tcgttcaacg
     6841 attttcccaa gtttcatcgg atatacaatc gcagtttatg atggccgcaa gcatgtacct
     6901 gtgtacattc aagaagacat ggtaggtcac aagcttggtg aatttgcacc aactcgtacc
     6961 tacaagggtc acgcagctga cgacaagaaa acacgtcgtt aataggagga ggacacaatg
     7021 gcagaaatta cttcagctaa agcaatggct cgtacagtgc gtgtttcacc tcgtaaaaca
     7081 cgtttagtac ttgatcttat ccgcggtaag aaagttgctg atgcaatcgc aatcttaaaa
     7141 ttcactccaa acaaagcagc tcgtgttatt gagaaaactc ttaactcagc aattgctaac
     7201 gcagaaaata actttggttt ggaaaaagct aacttggtag tatctgaaac atttgcaaac
     7261 gaaggaccaa caatgaaacg tttccgtcca cgtgcaaagg gctcagcgtc accaatcaac
     7321 aagcgaacaa ctcacgttac agtagttgta tcagaaaaat aaggaggtaa aatcgtgggt
     7381 caaaaagtac atccaattgg tatgcgtgtc ggaatcattc gtgactggga tgcaaaatgg
     7441 tatgctgaaa aagaatacgc ggattacctt catgaagatc ttgcaatccg taaattcatt
     7501 aacaaagaat tggcagaggc ttcagtttca acaattgaaa ttgagcgtgc tgtaaataaa
     7561 gttattgttt cacttcacac tgcaaagcct ggtatggtta tcggtaaagg tggagcaaat
     7621 gttgacgctc ttcgcgctca gcttaacaaa ttaactggaa aacaagtaca catcaacatc
     7681 atcgaaatca aacagcctga tcttgatgcc caccttgttg gtgaaaacat tgctcgtcag
     7741 cttgagcaac gtgttgcttt ccgtcgtgct caaaaacaag ctattcaacg tacaatgcgt
     7801 gctggagcta agggaatcaa aactcaagtt tcaggtcgct tgaacggtgc agatatcgcg
     7861 cgtagcgaag gctactcaga aggaactgtt cctcttcaca cacttcgtgc agatattgac
     7921 tatgcttggg aagaagcaga tactacatac ggtaaacttg gtgttaaagt ttggatttat
     7981 cgtggtgaag ttcttccagc tcgcaaaaac actaaaggag gcaaataaca gatgttagta
     8041 cctaaacgtg ttaaacaccg tcgtgagttt cgtggaaaaa tgcgcggtga agcaaaaggt
     8101 ggaaaagaag tatcattcgg tgaatatggt cttcaagcta ctactagctc atggatcact
     8161 aaccgccaaa tcgaagctgc tcgtatcgct atgactcgtt acatgaagcg tggtggtaaa
     8221 gtttggatta aaatcttccc tcacaaatct tatacagcta aagctatcgg ggttcgtatg
     8281 ggttctggta agggtgcacc tgaaggttgg gtagcaccag ttaagcgtgg caaggttatg
     8341 tttgaggttg ctggtgtttc tgaagaaatc gctcgtgaag cacttcgtct tgctagccac
     8401 aagctaccag ttaaatgtaa attcgtaaaa cgtgaagcag aataaggaga agacatgaaa
     8461 cttgaagaaa tcaaaaagtt tgttgctgag cttcgtggct tgtctcaaga agagcttgct
     8521 aagaaagaaa acgaactcaa aaaagaactt ttcgaccttc gttttcaagc tgcagcaggt
     8581 caactagatc aaactgctcg tttgaacgaa gttaaaaaac aaattgcacg tgtaaagact
     8641 gtgcaatctg aaatgaaata atagattggg aaaggagtat tctaaataat ggaacgtaat
     8701 caacgtaaaa cccttgttgg acgtgttgta tctgacaaga tggacaaaac aatcactgtt
     8761 atagttgaaa caaagcgtaa ccacccagtc tatggtaaac gtatcaacta ttctaaaaaa
     8821 tacaaagcac atgacgaaaa gaaccttgct aaagaaggcg atatcgttcg tatcatggaa
     8881 actcgtccac tttcagctac aaaacgcttc cgtcttgtag aaatcgtgga agaagctgtt
     8941 attatctaat caaactaaaa ggagacaatt gaaatgattc aacaagaaac tcgcttgaaa
     9001 gttgctgata atagcggtgc tcgtgagatc ttgactatca aggttcttgg tggttcaggg
     9061 cgtaagtttg ctaacatcgg tgacgtcatc gttgcatctg taaaacaagc tactcctggt
     9121 ggagcagtta aaaagggtga tgttgttaag gctgttattg ttcgtacaaa gagtggtgct
     9181 cgtcgtccag acggttcata catcaaattt gatgacaatg cggctgtcat tattcgtgat
     9241 gacaagactc ctcgtgggac tcgtatcttt gggcctgttg cacgtgaatt gcgtgagggt
     9301 ggctacatga agatcgtatc acttgcacca gaagtacttt aattttaatc attaaacaaa
     9361 ctaagtcccc taggctagcc tagggtgccc ataggggcgt aagaaaataa taggagaaac
     9421 ccataatgtt tgtaaaaaaa ggcgacaagg ttcgcgttat tgctggtaag gacaaaggtg
     9481 ttgaagctgt tgttcttaaa gcacttccaa aagtaaacaa agttattgtt gaaggcgtag
     9541 ccatcatcaa aaagcatcaa aaaccaaaca gcgaaaatcc tcaaggtgct atcgttgaaa
     9601 aagaagcacc aatccatgca tcaaacgttc aagttcttga taaaaatggt gttgctggac
     9661 gcgttggtta caagtttgta gacggcaaaa aagttcgtta caacaaaaaa tcaggcgaag
     9721 tgcttgatta atcacgaagg aaaggagaag cataatggca aatcgtttaa aagaaaaata
     9781 tactaacgaa gtaattcctg cgttgacaga gaagtttaat tacacatcag ttatggctgt
     9841 gccaaaggtt gagaaaatcg ttcttaacat gggtgtgggt gacgctgtat caaacgctaa
     9901 aaaccttgaa aaagctgctg cagaattggc gcttatctca ggtcaaaaac cacttattac
     9961 taaagctaag aaatcaatcg ctggcttccg tcttcgtgaa ggtgttgcta tcggtgcgaa
    10021 ggtgacactt cgtggcgaac gcatgtacga attcctagac aagctagtta gcgtttcact
    10081 tcctcgtgtt cgtgacttcc atggtgttcc aacaaaatca tttgatggtc gtggtaacta
    10141 cactcttggt gtgaaagaac agcttatctt cccagaaatc aactttgatg atgttgataa
    10201 agtgcgtggt cttgatattg ttatcgtaac aactgctaac actgacgaag aatcacgtga
    10261 attgcttaaa ggtcttggaa tgccttttgc aaaataatag ggggtaacta aattggctaa
    10321 aaaatctatg attgctaaaa acaaacgtcc tgcgaagtat tctacacaag cttacactcg
    10381 ttgtgaaaaa tgtggacgtc cacattctgt ttaccgcaag tttaagcttt gccgcgtttg
    10441 cttccgcgag ttggcttaca aaggccaaat cccaggtgtt gttaaagcgt cttggtaaaa
    10501 tgatgatgtg agagcgttaa gctacctaag caaaaatagg aaaattgacg aagagtctaa
    10561 atactctagg aaattttgca cctaaaggta gtagcttgaa ctcagttcaa atgaacaaat
    10621 aatactatca gatattatgt ctgattcgat gcaaaggcaa agtgtcaatt tgaacacggg
    10681 cgaaagccgg tgtcaaaaag ataaacattc cttggaggtt ttccctcctg cggaagtttc
    10741 ctattttgac tttggctttt agcgcccttt gtatcatcga ttaactagca agtgcagctt
    10801 gcaaactact agtaagagga gaataataaa atggttatga ctgacccaat tgcagacttt
    10861 ttgacacgta ttcgtaatgc taatcaagta aagcatgaag tgttagaagt acctgcatca
    10921 aatattaaaa aagggattgc agaaatcctt aagcgtgaag gctttatcaa aaacgttgaa
    10981 gttattgaag atggcaaaca aggaattatt cgcgtatttc ttaagtacgg tcaaaatggt
    11041 gaacgtgtca tcactaactt aaaacgtgtt tcaaaaccag gtcttcgtat ttattctaag
    11101 cgtgaggatg ttccaaaggt tcttaatgga ctaggaattg caattatttc aacttcagaa
    11161 ggtcttttga ctgataaaga agctcgtcaa aagaacgttg gtggagaagt tatcgcatac
    11221 gtttggtaat ttaagagaca aaagccgtaa cgaacaatct aaaattagaa aattattgtg
    11281 gcttgcttgc aaacaaaata gtttgtctat tttagatggc agttcgtcgg ctgtgctcaa
    11341 atgatgaaca ctatcaacat agcaaacgta aaagaactaa ttgaacatgg gctaaagtct
    11401 gtgtgaaaaa gataaatttt tctagaaacc ttggtttcat agtaatgttt cctattttca
    11461 ctttgccttt tacgccctaa gtatcttagt tcaccccgtg aaaactcgtc gcgtaagcgg
    11521 cctgataatt taacaggaga aaaaattaat atgtcacgta ttggtaataa ggttattatt
    11581 atccctgcag gcgttgaaat cattaacaac gacaatgttg ttactgtaaa ggggcctaaa
    11641 ggagagctca ctcgtgagtt taacaaaaat attgaaatca aagtcgaagg aaacgaaatg
    11701 actcttgtac gtcctgacga ctcaaaagaa atgaaaacaa ttcatggtac aagtcgtgca
    11761 aacttgaata acatggttgt tggagtttca gaaggtttca aaaaagagct tgaaatgaag
    11821 ggtgtcggat atcgtgcaca gcttcaaggc tctaagcttg ttctttcagt aggtaaatct
    11881 caccaagatg aggtggaagc tccagaaggg attacattta ctgtagctaa tccaacatca
    11941 atttcagttg agggtatcaa caaagaagtt gttggtcaaa ctgccgctta cattcgtagc
    12001 ctacgttcac cagagcctta caaaggtaaa ggtattcgtt acgttggtga gtatgtacgc
    12061 cttaaagaag gtaaaacagg taaataatgt tcttagtgga atatggcata ggcttgctta
    12121 tgtcatgctc tacaagctca attgataatt tgtcggaaag acaaacttaa atattaagag
    12181 gtgaaaattg tgatttcgaa accagataaa aacaaaatcc gccaaaaacg ccatcgtcgc
    12241 gttcgcggta aactctctgg aactgctgat cgcccacgtt tgaacgtatt ccgttctaat
    12301 acaggcatct acgctcaagt tattgatgac gtagcgggtg taacgctcgc aagtgcatca
    12361 actcttgata aagaagtttc taaaggaaca aaaactgaac aagctgttgt agtcggcaaa
    12421 cttgttgctg aacgtgcggt ggctaaaggt atttctgaag tggtgtttga ccgcggtgga
    12481 tatctctatc atggacgtgt taaagctttg gctgatgcag ctcgtgaaaa cggattgaaa
    12541 ttctaatagg gaggacacaa aataatggca tttaaagata atgcagttga acttgaagaa
    12601 cgcgttgttg ctattaaccg cgttacaaaa gttgttaaag gtggacgtcg tcttcgtttt
    12661 gcagctcttg tagttgttgg tgatggaaac ggacatgttg gattcggtac tggtaaagct
    12721 caggaagtac cagaagctat tcgcaaggca gttgaagctg ctaaaaagag catgattgaa
    12781 gtgccaatgg ttggcacaac aattcctcac gaggtttaca ctaactttgg tggagctaaa
    12841 gtattgttga agccagctgt agaaggttct ggagttgctg ctggtggtgc ggtacgtgcc
    12901 gtcatcgaat tagcaggtat tgctgatatt acttcaaaat ctcttggttc aaacactcca
    12961 atcaacatcg ttcgtgcaac tgttgaagga ttaaaacagc ttaaacgtgc agaagaagtt
    13021 gccgcacttc gtggcatctc agtttctgac ttagcttaag aaaggggatc atcatggctc
    13081 aaattaaaat tactttgact aagtctccaa tcggacgtaa gccagaacaa cgtaaaacgg
    13141 ttgttgccct tggacttggt aaattaaact cttcagttat caaggaagat aatgctgcta
    13201 ttcgtggtat ggtgacagca atttctcact tggtgacagt tgaagatgtc aaataaagag
    13261 ttagctagaa atctctgatt tcttgcatta gcatgcagaa ccggcttttg tgagttattc
    13321 ctttgaatga caagcagtgg tcggttggtg catatagcat caggctatga catagcttga
    13381 tcatgtatag gcgagtttct atggagagtc ctttcccttc atagaggcgc tagcatttta
    13441 caaaaaaagg agaaaaaatg aaacttcatg aattgaagcc tgccaaaggc tctcgtaaag
    13501 tccgcaatcg tgttggacgc ggtacttcat caggcaatgg taaaacatct ggacgcggtc
    13561 aaaaaggtca aaaggctcgt agtggtggtg gcgtacgtct aggctttgaa ggtggacaaa
    13621 cacccttgtt ccgtcgtatt ccaaagcgtg gatttacaaa tatcaacact aaagagtatg
    13681 ctcttgttaa ccttgatcaa ttaaacgctt ttgaagatgg cacagaagta actccagttg
    13741 ttcttaagga agctggaatc gttcgtgctg aaaagtcagg cgttaaaatt cttggtaacg
    13801 gcgaattgac taaaaaattg actgttaaag cagcgaaatt ttcaaaatct gctgaagcag
    13861 ccattactgc taagggtggt tcaatagaag tcatctaatg aggggatact cattatgttc
    13921 ttaaaaatac tcaaagacgc attgaagata aagaatgtta gaaataaaat attttttaca
    13981 atctttatta tccttatatt ccgtattgga acacatatca ctgttcctgg tgtaaatgca
    14041 aaaagcttag agcagctgag tgagcttccc ttcctaaata tgttgaactt ggtcagcggt
    14101 aatgcaatga gaaacttttc agttttctca atgggtgtta gtccctatat tacagcctca
    14161 atcgttgttc agctattgca gatggatatt ttgccgaagt ttgttgagtg gggaaaacaa
    14221 ggtgaggttg gccgtcgtaa gctaaaccaa gcgacgcgct atatttccct tgtcttagcc
    14281 tttgctcaat ctatcggtat tacagcgggt tttaacacct tatcaagtgt ggccctagtc
    14341 aaaacaccag atgtaagaac ctatttactg attggagctt tactgacaac aggtagtgtg
    14401 attgtgacct ggcttggtga acagattacc gataaaggct ttggtaatgg ggtgtctatg
    14461 attatctttg caggtatcat ttcctctatt ccaaatgcta ttgcaaccat tcgtgaggat
    14521 tattttgtca atgtgaagtc aggtgaccta cagtcatctt atatcgttgt tggtattctc
    14581 attcttgcag tgcttgctat cgtctttttc acaacgtatg ttcagcaggc ggaatataaa
    14641 attccaatcc aatatacaaa gcttgttcag ggtgcgccta caagctcata ccttccctta
    14701 aaagtaaatc cagctggtgt tattcccgtt atctttgcca gctcgattac aacaattcca
    14761 agtacgatta tcccgttctt tcaaaatggc agagatattc catggttgac aactttgcaa
    14821 ggaattttta actatcaatc tccaacagga atgattgttt atgccttgtt aattatcctg
    14881 ttttcattct tctatacctt tgttcaagta aatcctgaga aaacagctga aaatctacag
    14941 aagaattcgt cctatattcc aagtgttaga cctggacgag aaacagaaga atttatgtca
    15001 tccttgctaa agaaattggc aactgtgggt gctatcttcc tagcatttat atctcttgtt
    15061 ccaattgcgg cacaacaagc tcttaaccta tcttctagta ttgcattagg tggaactagc
    15121 ttgctgattt tgatttcgac aggtatcgaa ggtatgaagc agcttgaagg ttaccttctc
    15181 aagagaaaat atgtcggatt tatgaatatt acagaataga atatgggttg acactgtcaa
    15241 ccttctattt tgtttttaaa tgacaataag atttacagag ccttggttcc tatcttctta
    15301 ttgccatttg aaaacaaaaa caaggaaaac taaatttcct attatcttta tgtcaaaaga
    15361 ggagaaaaag atgaatcttt taatcatggg cttacctggt gccggtaagg gtacacaggc
    15421 tgcaaagatt gttgaaacct ttgagcttat tcatatttca acaggagata tgttccgcgc
    15481 tgcaatggct aatcagactg aaatgggagt tcttgcgaaa tcttatatcg ataagggtga
    15541 tttggtgcca gatgaggtaa ccaatggtat cgttaaagaa cgcttagcac aagctgatat
    15601 taaagaaaag ggatttcttt tagatggcta tcctcgtacc attgagcagg cacatgcctt
    15661 agatgaaacc ttaaaagcat tgggacttac gttagatggt gtgatcaaca ttgaggttga
    15721 ccctgcgtca ctcattgaca ggcttagcgg tcgtatcatc aacaaaaaaa caggggaaac
    15781 cttccataag atctttaacc caccagtggg agactataag gaagaggact tttatcaacg
    15841 tgaagatgat aagcctgaaa cagttaagcg tcgcttagat gttaatattg cacaaggtga
    15901 gcctattatc aagcattatc gtcaagcagg cattgttcgt gacattgacg gaaacaagga
    15961 catttctgag gtctttgctg acataaaaaa ggtcatcgaa aacctgaaat aaattccaga
    16021 aaatcgcttg cgaaagtgat tttatcgtga tatactagac tagtctgact tataattgtt
    16081 acctctgtgc tcagaggaca tcaaatcgaa atttaggggg tacttttgcg tggcaaaaga
    16141 agacgtgatt gaaattgaag gtaaagttgt cgaaactatg ccaaatgcaa tgtttactgt
    16201 tgaattggaa aatggacatc agattttagc aaccgtatca ggaaagatcc gcaaaaatta
    16261 cattcgtatt ttagtgggtg atcgtgttac tgtagagatg agtccttacg acttgacacg
    16321 tggacgtatc acataccgct ttaaatagtc gaaataattg gagggattaa aacatgaagg
    16381 taagaccatc ggttaaacca atttgcgaat actgcaaggt tattcgtcgt aacggtcgtg
    16441 ttatggtaat ttgtccgaca aatccaaaac acaagcaacg tcaaggataa gatagaaagg
    16501 agaaaaaatg gctcgtattg ctggagttga tattccaaat gataagcgtg tagtaatttc
    16561 acttacctat gtgtatggaa ttggtcttgc aacatctaaa aaaatcttag cagcagcagg
    16621 tgtctctgag gacattcgtg ttaaagattt gacatcagat caagaagacg ctatccgtcg
    16681 cgaagtggat acaattaaag ttgaaggtga tcttcgtcgt gaagtaaacc taaatatcaa
    16741 gcgtttgatg gaaatcggtt catatcgtgg aattcgtcac cgtcgtggac ttcctgtacg
    16801 tggacaaaac acaaaaaaca atgctcgtac tcgtaaaggt aaagctgttg cgattgcagg
    16861 taagaaaaaa taaaatagga ggtaaaaaaa ttggctaaac caacacgtaa gcgtcgtgtg
    16921 aaaaagaaca tcgaatctgg tgttgcacat attcacgcta catttaataa cactattgtt
    16981 atgattacag atgtgcacgg taatgcttta gcatggtcat cagccggtgc tcttggtttt
    17041 aagggttctc gtaagtcaac tccttttgct gctcaaatgg ctgcagaggc tgctgcgaaa
    17101 tctgcacaag aacatggttt aaaaactgtt gaagttactg taaaaggtcc tggttcaggt
    17161 cgtgaatcag ctattcgtgc cctagctgct gccggtcttg aagtaactgc cattcgtgat
    17221 gtgactcctg taccgcataa tggtgctcgt cctccaaaac gtcgtcgtgt ataatcacag
    17281 taacaaatag tacacaagtt tcgtttcgag gggtgaaaga atgattgagt gtgaaaaacc
    17341 aataataaca aaaattgatg aaaataaaga ttacggtaga tttgtaatcg aaccacttga
    17401 acgtggatat ggtacaactc taggtaattc acttcgtcgt gtactcttgt cttcacttcc
    17461 aggtgcagct gttacatcaa tcagaattga tggagtacta cacgaatttg atacaatccc
    17521 aggtgtacgt gaagatgtca tgcaaattat ccttaatgtt aagggacttg ctgtgaaatc
    17581 atacgtcgaa gacgaaaaga ttatcgagct tgatgtagaa ggtccagcag aggtaacagc
    17641 tggagatatt ctcacagata gcgatatcga acttgttaac cctgatcatt atctttttac
    17701 tattgctgat ggttatacat tgaaggcttc aatgactgtc gctaaaaaac gcggctatgt
    17761 accagcagag ggtaataaaa aagatgatgc acctgtgggg acgttggcag tagattcaat
    17821 ctatacgcca gtaaaaaagg ttaattatca agttgagcct gctcgtgtag gtagtaatga
    17881 cggctttgat aaattgacta ttgaaatcat gacaaacgga acaattattc ccgaagatgc
    17941 cttaggttta tctgctcgag ttttaatcga acacttgaat ttatttactg atttaacaga
    18001 tgttgcaaag gcaactgaag tgatgaagga agctgaaaaa gtgaacgatg aaaaggtact
    18061 tgatcgcact attgaggaac ttgatttgtc cgtacgctca tataactgct tgaaacgtgc
    18121 cggtattaat actgtcttcg atttaacaga aaaatctgag cctgaaatga tgaaggtccg
    18181 taaccttgga cgtaagagtc ttgaggaagt aaaggtcaag cttgctgact taggtttggg
    18241 actaaaaaac gataaataac ataggaggat aaaatggctt accgtaaact aggacgcact
    18301 agctcacaac gtaaagcaat gcttcgtgac ttaacgacag atcttttgat taacgaatca
    18361 attgtaacga cagaagcacg tgcaaaggaa atccgtaaaa cagttgaaaa aatgattact
    18421 cttggtaaac gtggtgatct tcatgctcgt cgccaagcag ctgcatacgt tcgtaacgaa
    18481 atcgcatcag aaaactatga tgaagctact gataaataca catcaacaac agctcttcaa
    18541 aaacttttct ctgaaattgc gcctcgttat gcagaacgca acggtggata cactcgtatc
    18601 cttaaaacag aaccacgccg cggagatgct gctccaatgg cgattattga attagtttaa
    18661 tttttatcaa ttttgttgag tgttatgatg atggagcagt tcctttaagc tgttcttagt
    18721 ctagctctgg tctaccgcta ggacctttcc tagcggtaac actcaccatg ttgagaataa
    18781 gtaacgcttg tttacgaaag gtctctaagc tgtaggtgcc cttcgtaagc aggcgttttg
    18841 ttgtgactcc atgttaactg tagtagatga ctaatatcta atatctagag aggatcagct
    18901 tggtgctctc ttttctgata ttaaaagcat tgggaatctt ggttttgaag ttcttaaagc
    18961 tcctaaagcc aaagtctttc gcttgatgtc tttggtcatc ttgttagtgg tctccggctt
    19021 agcattggaa taaggtagtt caaagcattg gtgatgtaag atctatactt cctgaaggtc
    19081 ttgaaaaccg ttttgaaggt gtgattgacc tgtagcggga gtagattaga tcaatggcgt
    19141 ttggctgctt tgaaaattta ggtgacaatt gtttttgtat ctttgtttaa aaatggtata
    19201 atattaaaac attaaacaaa atgtacataa aaaagccata taaaagaatg atattaagat
    19261 aatgtgatca atagttttag aaaatgaatg tgtaaggtta aggtatgccc ccttgatata
    19321 atgctagttt tacgaagagg cattctgtac agacataatg cactcttaca aatgatacgg
    19381 taattgctca acaaggcgca acagccttgg caaatgtaat atttgcctta gctagcagcg
    19441 aattagttac gcttgataca tagacaaggg tttctggcat acagcagcag atggtgtgcc
    19501 tgtctcagag agtggctgct tggcttatcc tattcatgtt ttaaaactta caggaggtgt
    19561 tatgtggcct ttggtcgatg gatatttagc taggtgaaca gctattagct gtaaatatga
    19621 ggtaggagct ttagtttgca tgatgttaaa tgaattgaaa cagacttagg aaagcttggc
    19681 ttagcaacta tcacgcaagt tcttaacaac gataaagatc gtatgggaaa atatgatcaa
    19741 gcatcaacgg acatgagatg tgttttatga agaaaccatt atacttttat aagacttatt
    19801 tagttgtttt tctttgcgga cttgtttgag gagtagtcta cataggcaat aggctcaggc
    19861 ttacagcact taggagacat tagagcatga gaagcactaa ctggctagtg atagaaaagt
    19921 aatagcacag tgtttttata actaacaaga ggagtagaca ttctatgagt attgacatgt
    19981 atttgagctt atctgaagag caggcacaga gtgtagaggc tgtcttagct aggcgacaaa
    20041 cagcctatca atccttacag gagaccttga tccaattgat ttctaacagt cctgatttat
    20101 cagggcggac ctatgattct gctaaggctt atagtagtca agtgctaatt cctttgttaa
    20161 aggggtgtat gcttttagat gaggcgatta taacagcctg taagaggcta cctagtgagt
    20221 accgtagtca ggtagaccaa attgatttga aggagagtga tctggttgag cgtattgccc
    20281 agttcgatca tgtgattggt cggtacatgg atttgattag tattgaatac agtagagagg
    20341 agcctagcta ttcttatatc tctcatttaa gatcagctga gcagctccat cgggccgtta
    20401 agcggcgtct tgaggagata ttgcgaaggc taaggcattt tgataccaac tcagttcacc
    20461 ttttttcgac tattcagact ttggcagcag cggtacaaat aggcatgcgt caagctagga
    20521 cctcgtggca tgcaggaagt caggtatttg tgatttcaga ggatatggca tgggccgata
    20581 cgattaattc taagtggtca aaaagtaaag ggttaagcta tcttagtgat tatgtttacg
    20641 acccagatgt gctctctaag agagcagcta ttaatcactc ttggattaaa acaggctata
    20701 ctatgtctaa aaattttggc aaagctgttt caaaagatta tacaaaagca agctttttga
    20761 gctatggtaa ggcagccaag gcgactggct ggacttctat ggcagtagat actggaataa
    20821 ctagtgtaag ggaatacaat aagaaaaata gtagagccta tggcagtgag ggcaaggcgc
    20881 ttattcatgc tagtgtggct caaatcaaga gcatgggacc tatagaaggg gcgataattg
    20941 gcagtaaagc tggaccttgg ggagcattaa tggggtttgt tacaggaggc attaatgtta
    21001 cttggggagt agtgcatcca gagtctaagg acaacatgtt tttatggata caagataaaa
    21061 tggatgatgt ttacgattcg attgttcaga cagatcttgg caaagggacg caccatgcta
    21121 aagaaagtgt caaaggtcat atcggtcgag ctattgtaag gacatgggac tttgtcagtc
    21181 aatcatttgg taaaggagtg ggctatgaca tttaaagatc agctttttag tgggacgttt
    21241 gagcaatcaa aaaagattgt gtctaaaagt atattgacag aagaaggtgc gcagattgga
    21301 gtattctcat ctatgagtct atggaagaga ataacaggct tgatgatgtt gccattattt
    21361 gctatttcat atggagtagg agttgtgtta cctgaacact ttcaataatc aacagaagga
    21421 gttcaagcta tttcattggc tgcaatagag attattgcca gattaggaca gttcagtcga
    21481 tactttatca tttgttttat ttgtatgtct gttggattaa ttattagtaa tatccttcca
    21541 aagcctaact aggcttatca attattatat ggcaatgcta ctcttattat acttagtatt
    21601 acaactatta tctcagcctt ccctttaact gctggcctta caattgcagc ttttggctgg
    21661 atcggttttt tgcttcagct attgctttgc ctttatttgt ggaaggtttg tgtcatagat
    21721 aagtgtcaac agctacgcac agcaatttat caagaaagca ccatagcacc tgattggggc
    21781 agtaagctag taagctttat taagtcttat ggtggtatct tattaggcct ctctgttctc
    21841 aaccgctgga ctctcaatct aggagagcta gtcaaggaaa gccctggttt gttgagtttt
    21901 ctgtacggct ggatttttct attgttcatg tttttgatgc tatttgcact gggtcaagcg
    21961 ttaaaaaata ccatcatagc ctattatttt tttagatatc aaaaagaata ccgcaagcat
    22021 tttaatataa gcgatgagca gtggtacggt aaatggcgtt taaaaatatt attaaaataa
    22081 acgatataag gagtaatcat atgcaaaaag aattattacc gttaggaagt gttgtctatc
    22141 tagagggagc aacaagcaag ctaatgattg tcggacgtgg tcctatattt gaatctaatg
    22201 gccaaaatgt ctacagtgat tatgttggag taatgtatcc agaagggatc aatccagaag
    22261 acgcgatttt tttcaaccat gaagatattg caaaaacagt ctttgaaggc ttcaaggacg
    22321 aagaagaaca acgcttttta gaagtgtatt ctgattggga gagtacttta gaaatttcca
    22381 aaataaagct atagatgaac tgtagcagat atatttgtca gtagattgtc atgattatat
    22441 tgaaagatta tgactttctc tggcttaaat acctctaaag ttccaaagtt tagaaaaggc
    22501 tttaaaatga gtgttataat agcatttatg ctcattaaat aaaggtagca tttcaataga
    22561 atcggtaaaa aaa
//
LOCUS       DARYUW010000034        22469 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYUW010000034 DARYUW010000000
VERSION     DARYUW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22469
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(93..563)
                     /locus_tag="TVW11_001232"
     CDS             complement(93..563)
                     /locus_tag="TVW11_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1365332.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            784..1634
                     /locus_tag="TVW11_001233"
                     /pseudo
     CDS             784..1634
                     /locus_tag="TVW11_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1970..2260
                     /locus_tag="TVW11_001234"
     CDS             1970..2260
                     /locus_tag="TVW11_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1365333.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2274..3413
                     /locus_tag="TVW11_001235"
     CDS             2274..3413
                     /locus_tag="TVW11_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365334.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3410..3892
                     /locus_tag="TVW11_001236"
     CDS             3410..3892
                     /locus_tag="TVW11_001236"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1365335.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3889..4476
                     /locus_tag="TVW11_001237"
     CDS             3889..4476
                     /locus_tag="TVW11_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1365336.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4473..4955
                     /locus_tag="TVW11_001238"
     CDS             4473..4955
                     /locus_tag="TVW11_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365337.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4980..5495
                     /locus_tag="TVW11_001239"
     CDS             4980..5495
                     /locus_tag="TVW11_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365338.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6129..7763
                     /locus_tag="TVW11_001240"
     CDS             6129..7763
                     /locus_tag="TVW11_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365339.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7904..8797)
                     /locus_tag="TVW11_001241"
     CDS             complement(7904..8797)
                     /locus_tag="TVW11_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1365340.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8781..8972)
                     /locus_tag="TVW11_001242"
     CDS             complement(8781..8972)
                     /locus_tag="TVW11_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365341.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9207..10961
                     /locus_tag="TVW11_001243"
     CDS             9207..10961
                     /locus_tag="TVW11_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1365342.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11102..11482
                     /locus_tag="TVW11_001244"
     CDS             11102..11482
                     /locus_tag="TVW11_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1365343.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11520..13853
                     /locus_tag="TVW11_001245"
     CDS             11520..13853
                     /locus_tag="TVW11_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1365344.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13902..14054
                     /gene="rpmG"
                     /locus_tag="TVW11_001246"
     CDS             13902..14054
                     /gene="rpmG"
                     /locus_tag="TVW11_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1365345.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14066..14242
                     /gene="secE"
                     /locus_tag="TVW11_001247"
     CDS             14066..14242
                     /gene="secE"
                     /locus_tag="TVW11_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1365346.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14633..15178
                     /gene="nusG"
                     /locus_tag="TVW11_001248"
     CDS             14633..15178
                     /gene="nusG"
                     /locus_tag="TVW11_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1365347.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            16221..17738
                     /locus_tag="TVW11_001249"
     CDS             16221..17738
                     /locus_tag="TVW11_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1365348.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            18020..18883
                     /locus_tag="TVW11_001250"
                     /pseudo
     CDS             18020..18883
                     /locus_tag="TVW11_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            19472..21973
                     /locus_tag="TVW11_001251"
     CDS             19472..21973
                     /locus_tag="TVW11_001251"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1365349.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            22160..>22469
                     /locus_tag="TVW11_001252"
     CDS             22160..>22469
                     /locus_tag="TVW11_001252"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365350.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     S"
BASE COUNT         6576 a         4115 c         5002 g         6776 t
ORIGIN      
        1 atcaaggctt ttgcaggaga tttatgaaaa agaaaaattt aggatagtgt aagtataagc
       61 tagtttcctt aagaaaagct taactgaagc aattaatcgt agagatgggt gattgttttg
      121 acgacttttt tctccttgtc agaccaataa tgaaggcgtt caaaagatcc ttgtcgccag
      181 tagagtggta gcctttgtcg aatatcctct tgcatgtcta gcttatctag atcagcaata
      241 gcatgccatt gtggtaggcc ctctcgtgat ttagttagca gcttgccttc aaaatcttcg
      301 caaagaaagt cataataaac atagcgctca ggcttatcag gattggtaaa gcctgagatt
      361 ccctttaatt gcagatttaa ggcggttaag ccggtctcct cctttagctc acgcactgcc
      421 gcttcaaaaa aggattctga ggtgttaacc ttgccacccg gttggatcca gccaggaaaa
      481 tcgtcatgct ggcggttgag aagtaggatc ttgtcgccct ccttgacaca gatattaacc
      541 caatttttga tgacttcaag cattagttac ctcgttttta gttttatttt atcaaaaaaa
      601 gatcagtatg aatagctgag agatttattg atatggtcat aatggcttca gatagtttta
      661 ctgctgcttt agccatctgc ataaataata taaaaatacc atttcacatc attatttaat
      721 agatttatta tcatattaat ggtataatta tgtgaaatta gaactatgtg tagagagagt
      781 ataatgaata gtacagattt gatgagactg ggagagcttt ataaggagct tcgtattgct
      841 cgtggactta ggctaaagga cgttgctaga gacaatttat cagtttcaca gctatctaag
      901 tttgaaaatg gccagagcat gctggcagct gacaaactac tattagctat ttcaggaatc
      961 catatgacat tcgctgaatt tggtcatgct gtaaatgggt ataaagtcag cgattttttt
     1021 cagttaggca ccaaggttgc cgagctacaa acagcatcag atatagatgg attgaaggag
     1081 cttctgagcc aatataaggg tgatgacatt ttttctgttt ataatagatt aaatgaatta
     1141 atcattaaaa gtgctatcta ctcacttgat ccaaatgtta aaattgaaga atcagacaag
     1201 caattgttga cagaatacct ttatagtatt gaagagtgga cggagtatga gctatacatt
     1261 tttggcggtt gtttggctat tttatctgat gaggatatga tttttttggg aaaagcattt
     1321 atcgaacgag ataagatttt cctttctctt ccacaacata gaaaggcagc tcacatcact
     1381 ctcttaaata ttatcatgac aaggcagctt tttatgttga tttttttatt aaaaagctgg
     1441 aggagttgat tatctatcaa gatatgttca ctatagtgag cttaaatttt tttaagaaaa
     1501 tatataccta cttaaatgaa gaaagtaagc ataagagcga cattgaagat tatattaatc
     1561 ttgttaaaca gcttggcaac cctcagtttg cccaaattct acatcggacg ctatcagtga
     1621 ttctagatag ttaatactaa aaaagtagcc caatcgtttg gtggctacag tggccaaggc
     1681 caccaaatag acaaaagggc taataagaaa ataaaagctt ttcgcataat atctcacctc
     1741 cttgataagg atattataca aaggggaagc ttcaatctca aacattcgca aatatgaaaa
     1801 tattaacaaa agcatcatca tatttgcgaa tatcgagaat atgataattg tcgtgatata
     1861 attactgtgt taatgattta gctaggcatt aataaatcta aatatagact acaggcaggt
     1921 cgctcgttat actagtttga gggccaatgg tctgggtagg aggaagcgta tggcgacatt
     1981 agagcgacat cataaaatgt tattattgtc aatggcatta ggggcagcga gctggttagc
     2041 actcggattg attagcttgc caaatcttgc aggtgcttta ggaataagta ctgctaatgc
     2101 caatactaca gttaatttgt tgagtgctta tagtacagtt tctagcgttg ttgcaatcgt
     2161 tggtgctgtt acgggtgtag ggtctattgg agctggaatt gcagctaccg ttttatacct
     2221 tatcaaacaa aaaggaaagg ctgctgctgc tctctggtag ttaattgtct gatatgaagc
     2281 atgttttcaa atatcataaa ggcgacattt tagggtatct caatattgtt gggtttaccc
     2341 ttttgtttta tggctcagtg ataggtatga taatgttcag ggattatttg acctatgatg
     2401 gagctggttc tctaatatcg acctttattc tggtatcagg aacctatcat tctgtgaaat
     2461 caacatttcc atatgaaggg aagcgtcatc caacttttat attaacaccc tattatctat
     2521 ttaagcatct attgctttca gttacaaagg tttatgcttt ccagatccga gtggttacta
     2581 taggaatcat ctgtttagca atagcctttc cggagcagct tgtttggata gccttgtctg
     2641 tgctagcagt atttatatat tggctatcgc ttccgctagt agccattttt cgagtagctg
     2701 gacgactcct gaatcttctc atgatttatg gtatgtatct taatcaggag ctgctggtca
     2761 ttgcttgtct ttgtttaaat gtggttattc ttgtgcttag tgttacgatt aatgtacatt
     2821 atccctacca atggctggcg gtgagagcta ggaaggaaga aaaaacaatt accttgttaa
     2881 agcttgttat caatacgata acagatcatt tagctttaat ggttctgttt agtattttct
     2941 gtatagctgt gacctatttc acgcaaaggc tgctgctaag ttttgattat tctagcttta
     3001 gcataccagt ttttttctta tctgcttcta cctatatcgc gttactagag gttatggtcg
     3061 gtaaaaatat taaggagctt gagttagacc ggggcttggc tgttttacag tttctgaata
     3121 gggatatcag tgtttacaaa gcttatcgca acagccaatt cttgctttct gctcacatct
     3181 tagctgttat tcatacagga tgtgccatag gcttactacc atttttacta aatggtcaag
     3241 ctgctctttt tctgtctaac ctagtgatga tccccttcat ctactttata tcattttgct
     3301 atttcgtgaa atcactaaaa atagttgctg gtgatttgtc agtgtttagg tgggttattc
     3361 tggttttgta ttttatacta gtggtcattg caatggtagg tagtcgttta tgataatgag
     3421 gaaattttta agatattata tcagttttat tattttctca atagcaattg ggattttaat
     3481 cggtttgctg atcaccagtg atactgtcat attatctaag ccagagcggg gctgggattt
     3541 tactctggag gttttgaaga ataatagcaa taattttttg tcctatattt tcctcttctt
     3601 tttgtcccca gccttgcaat tgattgattt ggtatcagtt gttatacaaa ttactctagg
     3661 aatgaggaag tctggatttc taataactgc cttgggtttg tttccgcatg gtttgctgga
     3721 gatccctaat tttctctttt atcaaggctt gagtcaatat atgctatgga ctgttttgac
     3781 tgaaaaaagc atgacgtcct tcttagaaag agaaagaaga tatgtaaggt actatcttat
     3841 atcgtattat gttttgttaa ttgctggtat tatggaaggg ttactcggat gaaaatagta
     3901 aatgaaagca agtcattttc aaacagaaaa atcttaaatc acatatcctt tgactttagt
     3961 aaagggctgt ataaggttga agggaataat ggtagtggta aaaccacttt tttgcgcttg
     4021 ttagcaggct tagaacggtt tgatagcggc catcgcttac agcataaggg agatattcta
     4081 tatcttgata ctaatgctat cggtgtagtt cccttaacta ttgaagacaa tctgacatta
     4141 ttatggaaaa cctttaatgc ctctcctgat gaggagacct tgtctgtgat taatcagttc
     4201 tttggagaac ggttactaga tcattatctg acggcttctg taggaacaaa ggctaaggtg
     4261 ggcttatcct tgctttttgt aaaggattgg gattatattt tcatagacga agccctatca
     4321 acgcttgatg ggtttagtct tgatatggtt gcaggaagat tattagcatt aaaagaaaag
     4381 gctactgttt tttacgtttc tcataatcta tcacaccagc agctattgtc agaatcacag
     4441 gtgatttatc ttaatggaaa aggagaaatc tattgaaagg taatcctttt aatcgtaatc
     4501 tttcttggtt aatagcctat gtgctattac tttcttgtta tgtattcata ttagtagatg
     4561 gtggtttttt aaaaaacagc gttcaagaat tggaagtcct gctcggccaa acatcactag
     4621 ctataaagct gtttttgatg gtgatatcaa tagcttttag catcatatct ttactggttg
     4681 agtatttttt aagcaaattt ttagtgctgc tttttattga agctggcatc gtttctttaa
     4741 atgatgttct tactgctaaa tcagtgactt tagtgatcca tttatctgct ttgctattga
     4801 agctatctcc ctctccactt tttcagtttg tagtgaatgc tttagggatt gtgatcatgt
     4861 atggattgag tatcaagaga caaggaaata ggacaactgc tcttttgttt tgtttaccct
     4921 ttacactgga tattctagca acattgttgc tttagtgatt ttgagttgga ggaaaagtaa
     4981 tgaaaaaaat cttatattta tcagtacttt taggaacgtc aattctagca acattgatta
     5041 aaatttataa cacttttttt gcaaagctaa aggcttcatc aggtcattca actgggaata
     5101 tagagattga tgccctttta tctgagtcta gactagtgtt ggaaaggcag catgccttca
     5161 caacaaatgg aatcaacaag ctattcgtta tgatgatgag tctaatgctg ttattagcct
     5221 tatactatct gataaaaaag gatttgaagg ccgtctatag ttatttgctt tacctggtgt
     5281 taaccttggt tcatgcaatt tatagcttct tttcgttaag tcccttggca aagctttatt
     5341 ctgatgatat gctgggggct acaatccaga cgggagagaa agctaaattg attttttcag
     5401 tggttctttt tcttctttat ctgcttattg ttgtggccaa taatagagta aaatctagtg
     5461 tagaacccgc ttcatctatt gggatagatg tgtaatacct ttcatattat gacctttaaa
     5521 gccttttagc ttctctaatt ttcagagtaa ctaggaggct gtttgtgacg ctctgagcgt
     5581 tttttcgttt ctatcaaagt ttagctgcgt taatgctatc tatttccgta gctgagatac
     5641 aagatattat aatatgtgtt gtcataccat aaaaacacct tacaggatat tttatgatca
     5701 atcctccttg aattaagctt tctttaagca agggtgtgta tactagccgt aatcctaaat
     5761 aattggttac ctaatgataa ctaatttttt cataacctcc ttcctaaaaa cgatgtcagg
     5821 gcagtcagga ttgattgctg ttatggcatc gtttttgttg tactttgata ggggatctag
     5881 ctgtatgtta aatagcctat caggattgag tggcgaagat gatcaggagt ctcttggctc
     5941 taggttatgc tgctgtttca tgagaaacag ctcttgatga tcaatttagg tagtattagt
     6001 ggtggtcatc ttagcctttt aggctttgag ctgctttatg tttgctcatt tttaatatgt
     6061 tagtgtttac acaaataatt ctcatttttt gatataatag aaaaggtaag gaagggtagg
     6121 agataaggat gacaagattt tttcaaaaaa aacaggccaa aagcttagcc attggttttg
     6181 tgagcttgtt tgctgtgctc attgggtatg gagcttttca ctattctaag gccagtcgta
     6241 tcaatgccta tctacaagca aggtcatcag gctctgggca ggtgcttgaa aatatcaagg
     6301 aatacctcgt gtgggcagat accaatgagc agctgaccaa tgatcaagca agatacacca
     6361 gctttaagag atacagtaag gcagagctag taagcaagcg tcagcagctg caaacagcaa
     6421 ctgcagctga tgatatgtat gtcaaatcgg ttggtcgcaa atttttgatt ttccctgatt
     6481 atcgcatagc agtgaagcct gtagccttga caatcaagac caatgtgcca aatgttgata
     6541 tcttgttgaa ccataaaaag attgctgtat cacagtcaga ggattttagc acaactattg
     6601 aaagactgcc ggctgctgat tataaggcga gtattaatgg ctattataag gatcgtaaga
     6661 ttaaagtcag caaggcctat gatggcaaga accatacact agatttgagg gttaccttta
     6721 agacatttac ggtaaccagc aatgtcagag atggcgagct ttatattgat ggcgagcgcg
     6781 tggaaacttt gaaggctggg cagcttcagc tggaagaata ccctgtgaca gaaatcgcaa
     6841 aggcctatat taaaaagacc tttcctgatg gcgagctaac ctccagcaag cattcccttg
     6901 ctcctgttgc tgagggctcc cagctagaga ttaacattga tcacctcttg actgaggaac
     6961 aggcgggaca ggtgttggtg gcagcctttg atcaattgct cacctatctc aatcaagggc
     7021 aggatccagc aggtctttca actgtttttg agcaaggggc taataatgct ttttacaaag
     7081 gcttgaagga ttccatcaaa gcaaaatttc aaactgatac cagaaaggct tctcggttaa
     7141 gcattccgtc tattttgtta agtaagctaa ctcaaattgg taagcagtct tatctagtgg
     7201 actttacagc tgtttatgat tttgtttacg ataaggaaac tgatcctgaa aaaggcacct
     7261 cagggaatgt tcgtcaagac ttgactggta agctgaccct gaaaaaatct ggggatagct
     7321 accttgttag tcagtctggt cctaaaaata ttacagttgc cagcgaaaaa aatcaggtca
     7381 agccgtctat tttcccagag gggctagtgg gaacctggat aggacatcgt tcggacatga
     7441 cctttacgat gatattggct aaggacggca gcatcacaac aaccattgga aacaaaaatg
     7501 ggaatggctc acagaccact aagtctgcta aaattaccaa ggtagaggaa aaaggagatg
     7561 gcttgttcct ctacactgta gctccagatg ctgatatagc agctcttgtt ccaggaggtg
     7621 gattgggtgg tgtcaatgtc aaatacgctt ttggtgtcaa atggagtgga gatgtcgcta
     7681 cgatagtggt ttggcagaca gcaaataatg cggcatttga ttacagtaag ccaatgcttg
     7741 gccctgacat gaaaaagcaa taagtacttt accctacaag ttggtctagc atttattgct
     7801 aggaggaatc agcataaaga aaaagcctct cttttaatct tttgtggtta agaagagagg
     7861 ctttttagta tagggctgac tgtatgagga gcaaccgatg taatcaattt agctgctgta
     7921 gtccttcttt aaagctttta gacggggcag tgaccctaat catctcttga gccaaggggt
     7981 gtctaagggt tagctgatga gcgtgcagca tgagacgctc cgctttttgc ctgctataga
     8041 ggggatcacc aattagaggg tgtttatgat gagcgagatg tactctgatt tgatgtgttc
     8101 gtcctgtctc taggcgacag ttgactaggc aggtctgatc aaaggcttgt aataaggcta
     8161 gatgggtgat tgcctcttgc ccatgcttac tatcaaccac acgcttgcgc ctatcgtggc
     8221 ggtgacgtcc gattggatcg cgataggtta ctgtttgctg ctctagctga ccttcgatta
     8281 gggcccaata atctcgctta atgtctcgat gctccaatag gcgatttaag atcggaagga
     8341 taaagggatt tttagcaaag agaatcgctc cactagtctc catgtctaag cgatgaacca
     8401 catagcaggt cttgccagta taggcagaga catggttgag caaggcgagc tcagtgggct
     8461 cattgccatg tgttttcatg ccctcgggct tgttgacaat gatgaggtgt tcgtcctgat
     8521 acaggcaatc cactaggcca ggcttaccca ttaagatgcc tttatcaggg tagtcttctt
     8581 ggtcaaattg tagcttgatg tgatcaccct gcttgacagg gctctgccag ttaatcagct
     8641 catcattgac ccaaacatgc tttttgatgc gcaagaaatg tctgatttta cggggaatca
     8701 atagcctatc ttctaataac tccttgacag ttgtcgcttg ataggggtta atgaaggaga
     8761 tctgaaagcc catctcaggc ttatttgctg ttgtcattga gccagtcatg gtatttttca
     8821 atcaaattga tggccatttg ggttgcaaga gttacagaga aagcctcggt tccctcgcgc
     8881 tcgtcactgg caacctctaa gcgtgtctca tcatagacag ccttgaggct ctctgctgac
     8941 agggtttctt taaaagcttg aaatttgttc atgatcatgt cctacctttc taaatgtttg
     9001 tgacaatgct attatagcat atttttcatc aaagctaatc atttgctcga tgatttgtgc
     9061 tgcgctaaca gcgtgattct tttgagaaaa aataagatta gctattgtga aattgtctgt
     9121 cttttattat actaagaata gtctgataaa tatattattt aaggacacga taacattggg
     9181 attatgaatc atttaggaga atactattga acaagccatt gataaaatcc tgtttgcttg
     9241 ctctattgac cttggccggc ttgaccagta tggcagcaca ggctgatgtc aacacttaca
     9301 accaaggtag gacatataac gatacaccct attattctgc ttatcatcac tactatgacc
     9361 acacgaggga tactgctgac aatggtattg ataattgggg tcgtctgaca cgctatcact
     9421 attacagaga gacctattat cagcttgagg ccgagcgtca gcagcttgtt aggacttact
     9481 tggagttgaa ggcttcatat gatgatcagg tggctcttag cagtcaacga ctacagcagt
     9541 accagtctgg ctggtctgat ctccaatcac gctttgagca gctcaggaaa accaatcctg
     9601 ttgtaggcgg tgattatcgg attgttgagc tagagggcaa ttttcaaagc tatcagacct
     9661 tgctgcagca gctttctatg gctgattttg tcagccagta caaagatagg ctggatacct
     9721 tgactagact tgatacagag cgagctaggc tcattgacac ctggtgggaa agtgatagca
     9781 attactcaga tctcaatacc aatctaacac tagtcaatgg ctatatcaag gagctgaatc
     9841 aggctttaca ggagcttctt aaggaccatc aaggtaaaat gacatcagat ctgcagacct
     9901 tgggtgaccg acaggccgag cttgctagac ggctgacaga tatagaaagc aggcctaaga
     9961 gacaggctac cagtcaacct cgtggttcac agacacattg gcgatcagcc cctagagctg
    10021 atgttgcctt gtggaatgaa ttgcgaaacg aaggagatta tgcttctgct acgacagaca
    10081 atgctttgcc attgcagcct tatcgagcgg acttaacagc tgttcatgat ctagaagcct
    10141 tgcaagcaca atctgataga gcacaccgct tgcgggcaaa ggaaattgtc tttacactgc
    10201 agcgttctaa cattagtcgt cagggcgata tagatttgtc aggagccatt acagcattta
    10261 tcaaagaaaa gcttctcgtc actccaaatg cgcgtggggt atcatctggc tttaggtggc
    10321 aaatgcaaac ctatgacaat gagcgcttaa ccatcactct aatgcctcaa tattatatga
    10381 ctgatgatca gtacaaggag tattacgacc atctcaaggc ttggacagct cagcatatcc
    10441 agtctaccga tacagaggtt gagaaaattg ataagattca agactatatc atgacaaact
    10501 accactatgc gaccggcaag gttggaggag tgacccgtac tggcatttct gtgcagacgc
    10561 catatgcctt tatcaaggac aaggaggctg tttgtcaggc ctatgcacag atgtttaagg
    10621 acatgggacg actagctgga cttgatgttc attatattca aggctatgga gacccagttg
    10681 gcggcttatc aagtctacat gcttggaata tcgtcaaggt tgatggtcaa tattatcata
    10741 ttgacctgac ttggaatgat actattgaca gcaccaatca caatcatacc tacaccctgc
    10801 gaggcaatga ttttatgagc aaaacacatt tgtggaatgc tgcctatgcg atctcagata
    10861 gtgactatgc tgcttatcct aggaggagct tcctgagata tgggacctat gcgactaact
    10921 attcaagaaa tacattttat ccaggataca gttatgctta ataatagcta ataccatcaa
    10981 aagccctaga aagcttgctt gattctttca gggctttttg atatgtcatg gtttttggta
    11041 taggattttg aaagaaattg ttataatagg ataaaatgct tatgtaacag gagaaaataa
    11101 aatgaagagt attagacgct atgatgtcaa tgaagagtgg gcacatactg gcttagtaga
    11161 ggcaggcgat ttttattttt taaattattg tgtaggaaat gtcggtcaag atattgaggc
    11221 tcaaattaac ggtgcctttg atgaaatgga gcgtcgtttg gggctggtag ggctgacgct
    11281 agaggtcgtt gttcaaatgg attgcttgtt tagagacatt tggaatgtgc cagttatgga
    11341 aaaaatcatc aaggagcgat ttaatggcaa atacccggct cgtaaatttc ttcaaacagc
    11401 ctttgctcat cagggtggtc cggacggctt gctatttcag gtagatgggg ttgcttattc
    11461 aaagcatatc tccgtatcct aaacaatatg acttggaggc ttagtagtat cataaggcta
    11521 tgacattttt agaattatta caaaagaaat tttttccaaa aaaataccaa gaaaaacagg
    11581 ccttaaagga aagggcagcc cagcatatgg ctgacaaaga ggctactact caggctactg
    11641 ccactgcttt ggccgatcag gaggcacagg cagggcagac tgagaggcaa tcagtccttc
    11701 aacgcagcaa gtcctatggg gtcaaaagga aaaatcggcc gatctggctt caaaggctgg
    11761 aggcgatttt gccatcgcag caaggtccta ttcgccgctt tcttcgtcgt taccatgttg
    11821 gtaaaatcct gctgattttg atgggtacct ttgtcttgct gctggggtct tacctttttt
    11881 acctttcaaa gacagctaag gtttctgact tgcaggacgc tcttaaggcg acgacagtca
    11941 tctatgaccg caagggagaa tatgcaggca gtctttctgg tcaaaagggg acctatgtgg
    12001 agcttgacgc tatttcagat gatttggaaa aggcggttat tgccacagag gaccgtacct
    12061 tttataccaa caatggtatt aatttcaagc gctttttatt ggctattgtg accgcaggac
    12121 gctttggtgg aggctcgacc attactcagc agttggctaa aaatgcttat ttgtcccagg
    12181 agcagagcat taaaagaaag gcgcgtgagt ttttcttagc acttgaattg accaagaaat
    12241 acagtaaaaa tgacattttg accatgtatc tcaataattc ctattttgga aatggtattt
    12301 ggggtgttga ggacgccagt caaaaatatt ttggtacctc agcagctaat ctaaccttgg
    12361 acgaggcagc aacccttgcc ggtatgctca agggacctga aatttacaat ccctattact
    12421 caatcgaaaa ggcaaccaac cgtagagata ctgttttgtc agccatggtt gacgctggaa
    12481 aaatcagcaa gcagcaggca caagaggccc aagctattgg tatggggaac cgtttagcag
    12541 acacctatgt cggcaagaca gatgattatc agtacccatc ttattttgat gctgttatca
    12601 atgaggctat ctcgcgctat ggcatctcag aaaaggatat tgtcaatgat ggctacaaga
    12661 tttacacaga gttggaccaa aattaccaag caggcatgca gaccaccttt aatgaggata
    12721 gcctatttcc tgtgtctgag tttgacggca gctcagctga ggcggctagt gtggctctag
    12781 atcctaaaac cggagctgtc agggggcttg ttggtcgtgt caatagcaca gaaaaccagc
    12841 cctttagaag ctttaactat gctactcaag ccaagcgtag ccctgcttca acgatcaagc
    12901 ccctagttgt ttatactcct gctgttgcag caggctggtc actggagcac gaactgccaa
    12961 acagcgttca ggattttggc ggttatcagc cgcataatta tggcaattac gaatcagaaa
    13021 caattcctat gtatcaggct ttggctaatt cctacaatat tcctgctgtt tcaattctgg
    13081 atcagttggg ggtggataag gcctttagct atggtgaaaa atttggtttg aagatgagtg
    13141 aaaccaaaaa ggagcttgga gtggcgcttg gtagtggtgt caccaccaat ccgcttgaga
    13201 tggcacaggc ctatgcagtc tttgccaatg gtggtgtcaa gcatattgcc cacctgatta
    13261 ccagaattga aaatgctaag ggcaaggtta tcaagacctt tacagacaaa accaagcggg
    13321 ttatcagtca atcagtggct gataagatga ctagcatgat gcttggaacc ttttctaatg
    13381 gtacagctgt taatgccaat gtctatggct atactctggc tggtaaaaca gggaccacag
    13441 aaactgactt taacccggac ctttccggtg atcagtgggt cattggctac acgccagacg
    13501 ttgttatcag tcaatgggtt ggcttcaatc aaaccgatga gcatcattat ttatcagatt
    13561 caagtgcggg cactgcctca gcaattttta gcacccaagc ctcttatata ttgccatata
    13621 ccaaaggaag ccaattcaag gtcgataacg cttacgctca aaacggtatt tcagcggttt
    13681 atgggattaa tgagaccaat acgcaagcag gtattgattc tcaatccatc attgatagtc
    13741 ttagaaagtc agccgaggaa gcttcaaagt ctatttcaga ggcagttgat caatctggtc
    13801 tcagagaaaa ggcgcaaagt atctggaaga gtattgttga ctactttaga tagcttgcga
    13861 aaatatctaa atcgtgttag aataatcact acggaggcgt tatggcacag aaaaaagcaa
    13921 gcctagcgtg tgtagaatgt ggcagccgca attattctat cgggattagt agcacgccta
    13981 gaccaacacg actagaagtc aataagtttt gcaaatattg taaagcatac accttacaca
    14041 aagaaacacg ttagaggaga gcctgatggg attcattagt gggattttta agcttttaag
    14101 ggatacaact tggccggatc gtaagcagcg ctggaaggac tttatttctg tccttgagta
    14161 tacagcattc tttacggtaa tcatctttat ctttgaccag ttgctatcaa aaggcatttt
    14221 atcattgatt aatttattct aagtcattgc aatgatgaga cctgttatga ttaaaattgc
    14281 ttggaaaagc ctaggctgaa acaatcgttt cggccttttt gagtgcgatg ggcaggttgt
    14341 actctgatag atgcaagacc aatagaccac ctactatgcg ggtgcgtaaa ggggttgata
    14401 gctaccgata gttaagggct atagcaagta gaaaggcttg cagctcagct gatccgctgt
    14461 tatgactaaa ggcattgacc agaaaggttc gttggcagcc aacaaagtgc tcttaccctg
    14521 ctatgagggg ctattaatgc gttgacagcc aatccttctt ctattataat gaaagtgtga
    14581 taacagcaat gcaaaggcca gcagaggctt ttttataatg aaaggaagta acatgttaga
    14641 ttcttttgat aagggctggt ttgtccttca aacttactca ggctatgaaa ataaagtaaa
    14701 agaaaacctt ttgcagcgtg ctcaaaccta taacatgcta gacaatattc tccgcgttga
    14761 gattcctacc caaacggtaa atgttgaaaa aaatggtcag gtcaaagagg ttgaggaaaa
    14821 ccgcttccca ggatatgttt tggttgagat ggttatgact gatgacgctt ggtttgttgt
    14881 tcgtaacaca ccaaatgtga caggctttgt cggatcgcat gggaaccgct caaaaccaac
    14941 ccctctactt gaagaggaga ttcgtgctat cctgttgtca atgggacaaa ctgttgatgt
    15001 ctttgatacc aacattaaag agggcgatat ggttcaaatc attgatggcg cctttatcgg
    15061 gcaagagggt cgtgtcgtag aaattgaaaa caacaaggtc aagctcatgc ttaatatgtt
    15121 tggctcagaa accttagcag aggtcgagct ttaccaaatc gcagagctat cgtcctgata
    15181 ggctcctaaa gctattattc ataccataaa aaataaaagg ctggcatcgg ctctctaaaa
    15241 taccgatgtt aggccttttt tgttggtctt ctacaaccaa gactcaaatt aaccaaaccc
    15301 taaaaagagt catttttcct tcgcttttta agtctctaac tgatcgccct agcttatttt
    15361 taatctagta atcgcaacag gtcaagagtt aaatgatatc gcgccgttat tgattggtat
    15421 agacaaaaat acgctcaaaa aaagaaaaaa ggataggtaa tatagtcctg gtttgcttga
    15481 tagatggtgg ttggcaacca accattcgag tactttcctt aactataaac tcctaatcaa
    15541 ttctagcgtt taaaaaataa gattattctt ggagggaagc aaagagcttc tctccttttt
    15601 gagttgtagc attcttgatc ctgatcttat aagcagagtc ctgtttgccg ggctgttgag
    15661 atgaataagg gcatttctat agtgattata tagtgttgca gatgtgtgta tggtttaagg
    15721 tctaaatacc cttcaagctt agttcttggg tagtcagttc ggattggctg gctgattttt
    15781 aagcctttaa tggcttagtg gtaagacaaa ccagattaca tttgctaaaa agtccctaag
    15841 gctacaatca ttttttgtga ctaatataaa aactagacct tttgggattt gtaataattt
    15901 agattattgt ttttaaaatt agcaaatatt aaacgctttt ttattgaaga tacagatgat
    15961 agtaatggca gagctaaaaa ataagagaaa ataaaaaaag tctacaattt ataatgtaat
    16021 aaaaaaatga gttgactgtt gtgttttaaa ggcttttgtc tatttgtaat cggttaattt
    16081 gcaaacaatt ctaaggtatt tctggctaat agtatgctat aatgtaatac tgttctacaa
    16141 ccgacattaa gagttaatga aatagtgttg tgttgtggta agtttttaat caggaagagt
    16201 atatttagga gctagatacc atgtctatag agaatctctt taccaagcag cagtggcgag
    16261 agcttgagtt gattacttta ttaagtgaaa cgaaaaatcc attatattat aaagatgctt
    16321 gtcagatgct ggattgttcg gttttaacgc tgcaatcgtg tatcacgaat tctgttttta
    16381 tggaagattt aggcaagctg ttctacaagg attctcaatt tcatattcat tacaatcatc
    16441 aaagtggctt aaaggaggtt tatcggagag ccttgctaga gtctccttct cttcagttga
    16501 tgtcggcctt gttttttgat gattttgcgt cattagatga tcttgcagag gcacttttta
    16561 ttagcttgtc aaccttaaag cgcttgattc gtaaaaccaa tctctattta aaagagcatt
    16621 ttgatattat catttcggct aagcccattc gtgtagttgg agatgaatac aatattagac
    16681 tgttttacat caagtatttt tcagaagcat ataccttttc tgaatggcct tttgcttctc
    16741 tacttaatga aaaccaccat gagcaatttg ttcaattaat ggcatctttg atagaggtta
    16801 agattgattt tgcgattttt cgtcaactca agctattaag tgcggttaat ctcattcgct
    16861 acctcaaagg ctttaaaatt gggaagcata aagcactgag tagtctttca ttggagttgt
    16921 tacaggattc tcaggagatg aaaaagctgt cgcatttgtt tgtgcttaaa ttttcagtac
    16981 cgcttgatga gcttgtcttg tcagaaatgt tttccaatta tttagatgat gatttggtat
    17041 tagaaaaatc cttgcaggta gataaggtta aggaggaggt tccgggtcct cagtccttgc
    17101 tgagctggat agatttgctt agtgaaatgg agggagctac aggtattgta ttgccaaata
    17161 aatatgaggt tgccagatat cttcatgcca ctgttatttt aggagtggag gatattagtg
    17221 aaagctttct gatttacgat tataaaaagg attacttggc cttctttaag gagcattata
    17281 cctatgttta ttttaggttt accgattatg tgaagaggct atttaaggac ggggatatgg
    17341 agcttgctac taatttgctc aacaatttgg tttattcctt gctgatagcc tgggagaatt
    17401 tctttttaac catgtgtgaa ttgatgaaaa aaccaaagct cttgattata gaaagaagtc
    17461 atggcagtac gggaagcttt ttgaaaaaat acattggtga attttttgag attaccattt
    17521 ttgataaatt aaccatagaa gccttgtgtc tacagcatga ctatgacgtc attattactg
    17581 atacggtcat taggggctgt gagcatgctg atatcttttt ctttagtcga tttgtgccaa
    17641 ccgttatagt cgccaagctt aaccattatc taagaaaacg aatgggtagt atctttgaaa
    17701 cgaaaacaac taacaagctt gggaacatcg gctattgata gatatcggta tatttcatta
    17761 aaatagccac aacttgtcat ggtgtaaaat tagtgagctt tgttaatcca ataaaattag
    17821 gtagaatata gctataggcc aacgtgtaat tcccttaggg agtaggtgct ttggtctggg
    17881 aaagagaaaa ataaaaagga gaaacaaaca acatgaagag ttgtaaatca accctagttt
    17941 agataaaaag attaattctt ctattggtat caaaggaagt aattttattt cctcaaaact
    18001 tttagcgaat ttaaagactc gcatcgactc tgaagctact ttgaaagcag aaacaactca
    18061 attgaaagcc gatatagaaa gagaaaaact tacttctaaa gaattaagca ctaaactgga
    18121 agaggtaaca tcagatcgtg ataatgctct cagtgaatct gccgatcttg ccaacaaact
    18181 ctcagtagct caagcagaag cagatcgttt aagtcaggct gttgatagtc tgggtcgatt
    18241 gactaactct gctaagcgtg agctcacaga gaagcttgct gagattgatc aattaacaca
    18301 ggacaaggtt aaagcagaga ctgaccttga aactgctaat gctaacatca caacacttca
    18361 agaggagctg gcaggtgcta aggctaatgt tgataagctt gcaaaggaaa aagctgcggc
    18421 agatcaggca cttgctgaag ctaatgcaag agtatcaaat cttgggcaag aggtagcagc
    18481 agctaataat agagtggctg accttgaagc gcaattagct gaaaaaacag ccgagcttga
    18541 tgtggttaag gcagacaagg cagagcttga ggctaaggtt aaggagcttc aaagcctgct
    18601 tgagcaaaag gatcgtagca atgctgatct tcaagctaac attgagcgct tgaagcagga
    18661 gcttgctgac aagtttaagg atcaggcaca gcctcgttct aagactcctc aggcatcgaa
    18721 ctcggttgca aagcaaaaag caagtaagcc agccgcaaaa ccagcaggcc agctaccatc
    18781 aacaggtgaa gctactgcaa atccattttt cactgctgct gcagttgcga ttatgacaag
    18841 tgcaggccta gtaacagtca tgccaaaacg ccaaaaaaat taagctattc tcaattctct
    18901 cccctttaac tattgtttta tagcatttta ctaatggaca ttggcattcc tataaactct
    18961 attgagcttc ttatctgata gcaaggataa ggggcttttt agtagcttag caagcactcc
    19021 ttggtcaagc tcaatacctc tttgagagct taaaactaga gctagaccag atctaaaacc
    19081 aagtgagatg atagcggata tttggctgtt ttatgagttg gctcgtaagg cttgagctta
    19141 tgcgtcgcag agacgcgcta tctagtctaa agggctttag caatgtcgtg acaaacgcat
    19201 gaagacagtt acactttctc atagcgagtt tttatcatca gtatagtttt tttggcaata
    19261 tgttatgaaa tagtcaaata gcaatcgaga aactggtgat attgcaatgc aaaaccgctg
    19321 aacatagatt aaaaaaatgc atgcagctag aaaatggtta catgcatttt tgtgatgccg
    19381 acgtcgtggc agcaatattg cttgcccatt cctaaaagtc tgatatcgtg ctataataag
    19441 aagactagac tttttacatg ggagaattca catgacattt tacaatcaca aagccattga
    19501 gcctaagtgg caggcctttt gggctgataa tcataccttt aaaacgggga cagatgcctc
    19561 aaagcctaaa ttttatgctt tagatatgtt tccttatcct tccggtgcag gtcttcatgt
    19621 tgggcatcct gagggttaca ctgcaactga tattttaagc cgcttcaagc gtgcacaggg
    19681 ttataatgtc ctccacccaa tgggctggga tgcctttggt ctgcctgctg agcaatacgc
    19741 gatggatact ggtaatgacc ctgctgagtt tacagcagaa aacattgcca actttaaacg
    19801 tcagatcaat gctcttggct tctcgtatga ctgggatcgt gagatcaata caactgatcc
    19861 tagttactac aaatggacac agtggatttt cacaaaattg tatgaaaaag gcctagccta
    19921 tgaagctgag gtgcctgtta actgggttga agagctggga acagctattg cgaatgagga
    19981 ggttctccct gatggcacat cagagcgtgg aggctatcca gttgtccgta agcccatgcg
    20041 ccaatggatg ctcaaaatca cagcctacgc agagcgcttg ctagcagatc tggaggaagt
    20101 ggattggcca gagtcgatca aggatatgca gcgcaactgg attggtaaat caacaggggc
    20161 taatgtaacc ttcaaggtca aagataccga taaagacttc accgtcttta ccacacgacc
    20221 tgataccctg tttggtgcaa cctatgctgt tttggcacca gaacacgcct tagtagatag
    20281 cattactaca gcagagcaag cgcaggctgt tgctgagtac aaacgccaag cgagcctcaa
    20341 atctgacctt gctcgtaccg atcttgccaa ggaaaaaaca ggtgtctgga caggagccta
    20401 tgcgatcaac ccggtcaatg gcaaagaaat gcctatctgg attgcggatt atgtgcttgc
    20461 aagctacggt acaggtgcta tcatggcagt gccagcgcat gatgagcgtg actgggcatt
    20521 tgcaaagcaa ttcaatcttg agattattcc agtgcttgaa gggggcaatg ttgatgaggc
    20581 tgcctacaca gaggacggta ttcacattaa ttctgacttc ctagatggtc ttgataaggc
    20641 ttgtgccatt gctaaaatgg tggcgtggct ggaggagact ggtgtcggtc atgaaaaggt
    20701 ctcttatcgc ctacgtgact ggctgttcag tcgtcagcgc tactggggtg agccaatccc
    20761 aatcattcat tgggaggacg gtacctcgac agcggttcct gagcaggacc taccacttgt
    20821 tttgccagtg accaaggata ttcgcccatc tggtacagga gaatcaccac tagctaactt
    20881 gactgactgg cttgaggtga cccgcgagga tggggtcaaa gggcgtcgtg agaccaacac
    20941 catgccacag tgggctggct caagctggta ttaccttcgc tatattgacc cacacaatga
    21001 tgagcaatta gctgataagg acctgttaaa gcaatggctg ccagtagata tttacattgg
    21061 tggtgctgag cacgcagtgc ttcatctgct ttatgcacgc ttctggcaca aggtactcta
    21121 tgatctgggt gtagtgccaa ccaaggagcc cttccaaaag ctctttaatc aaggcatgat
    21181 tttgggaacc agctatcgcg accatcgtgg ggccttggtc gcaacggata aggttgacaa
    21241 gcgtgatggt agcttcttcc acatggaaac aggcgaggag cttgagcagg cccctgctaa
    21301 gatgtctaaa tcactgaaaa acgttgtcaa cccagacgat gtggtggagc agtacggagc
    21361 agataccctg cgtgtgtatg aaatgtttat ggggccactt gatgcgtcca ttgcttggtc
    21421 tgaagaaggc cttgagggag cacgcaagtt cctagatcgt gtttaccgtt tgatcacgac
    21481 aaaggaaatt gttgcagaaa atagcggagc tttagataag gcttaccatg agactgttaa
    21541 ggcagtcaca gaacaaatcg aaggcatgaa attcaatact gctattgccc agctcatgat
    21601 ttttgtcaat gcagccaata aagaggacga gctttatgtg gcatacgcca aaggcttcgt
    21661 tcaattgcta gccccatttg ccccacacct aggtgaagaa ttatggcaga tcctgacagc
    21721 ttcaggtcaa tccatctcgt atgttgcatg gccaacccat gacgatagta agctcgttga
    21781 aaatgatgtt gaaatcgttg ttcaaattaa aggaaaggtc aaggctaagc ttgtcgtggc
    21841 aaaagacctc tcaagagaag agctagaaaa agtagcccta gcacatgata aaatacaggc
    21901 tgaaattgca ggcaaggaag tggcaaaggt catcgttgtt cctaataagc tcgttaatat
    21961 tgtggtgaaa taaagaccct agcaaaaaat gccttcctta taattttgag cccaatacta
    22021 taaaaagctg ataaccactc gtttacatga gtggttattc ttgttttgta acacgctatt
    22081 aaaactgata ttgaagaagc ttgaagataa tagtaaaata aaaccctaaa cttatttaat
    22141 aaatggagga tttttcaacg tgaaaaaatt agttttagcc agtgcagcag cacttgtatt
    22201 agcaggagca actgtaagta caggaacagt aagtgcgaat agttcaagat ataattatac
    22261 cggttggaat caaggtgggt actcatggaa atatttgcgc ctaagaaata aaaatcctta
    22321 ttcacgtcgt acccttacag aagactattc tgatcaaaga aagaatgaag caaaagatag
    22381 tattaaagaa ttgagtaagc ttagtgataa agagaaaaag aattttgctg atagaattga
    22441 tgctttgact gacacctatg caatcagct
//
LOCUS       DARYUW010000035        21536 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYUW010000035 DARYUW010000000
VERSION     DARYUW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21536
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            173..400
                     /locus_tag="TVW11_001253"
     CDS             173..400
                     /locus_tag="TVW11_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365351.1"
                     /translation="MTKDDFLTGFVLILLAACIFAVGFAIGHDYSSEHYEQKITDLQI
                     QLVSTQQQLKQSREQNQSQTKRIANLTGNGG"
     gene            411..1100
                     /locus_tag="TVW11_001254"
     CDS             411..1100
                     /locus_tag="TVW11_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1365352.1"
                     /translation="MEIKCGNCLELLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGADLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLAVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVSGAEKTQH
                     PTQKPVALMRDIITRHTTKRAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAN
                     KRIAELTGNGG"
     gene            1102..1893
                     /locus_tag="TVW11_001255"
     CDS             1102..1893
                     /locus_tag="TVW11_001255"
                     /inference="COORDINATES: protein motif:HMM:TIGR00675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1365353.1"
                     /translation="MLRVFEAFAGIGTQRMALRNLGIPHEVVAIAEIDKFAIKSYEAI
                     HGPVNNLGDISKINPDTIPDHDLFTYSFPCQDISVAGKQAGLDIDSGTRSGLLWECQK
                     VIVAKKPKYLLMENVKNLVGKKHKPNFDKWLDWLESQGYTNDWQVLNAKDYGVPQNRE
                     RVFCVSILGEHKPYIFPEKQELTIRLKDILEDDVDEKYYLTTNKANELLATIVRENDV
                     SERVVVDSTIKKPKIKNVMNAVIGRYDAGIRNQQSVGGAVIELIE"
     gene            1835..2380
                     /locus_tag="TVW11_001256"
     CDS             1835..2380
                     /locus_tag="TVW11_001256"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1365354.1"
                     /translation="MQASEINNRLEVLSLSLLNKNATKKGYLVADDGDGIDTAYPDSK
                     TRKGRVQKNMSHTITTDDSKAFLIGASRGRDPENPNDRSAGNQNLQQRLEINKNGTSN
                     TITSVQKDNYAVEFPDYRIRKLTPLECWRLMGCSDEDFEKAQSVNSNSQLYKQAGNAI
                     VVDVLEAILKQLFLTEAQNEH"
     gene            2370..2888
                     /locus_tag="TVW11_001257"
     CDS             2370..2888
                     /locus_tag="TVW11_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1365355.1"
                     /translation="MNIEEAKQKLHNMAYRDLQTKPYDLKLADVIQILNQIKLDKPQP
                     EIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFEKQETFVNAFLYGYTIEKE
                     KLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSHIHLRDDLRLTESEIRKDFDW
                     AWREEFPKEVTE"
     gene            2915..3214
                     /locus_tag="TVW11_001258"
     CDS             2915..3214
                     /locus_tag="TVW11_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365356.1"
                     /translation="MNYDKKKSDLKKRLIIGFTLLPISIVLSGFVIKYGWNNILSTID
                     GVPPINLPQAIAIDVLVSFIIAKTNAEGDFATEVGRAFISPLMTLLLFWVVTLFM"
     gene            3231..3404
                     /locus_tag="TVW11_001259"
     CDS             3231..3404
                     /locus_tag="TVW11_001259"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365357.1"
                     /translation="MTEELGVLLDKEGVEYVKMVFDDGFVWTIRNPLNAALLKRQDAE
                     QFPQFTWVPLTDL"
     gene            3741..4181
                     /locus_tag="TVW11_001260"
     CDS             3741..4181
                     /locus_tag="TVW11_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1365358.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALMSFSELYKEGMLLVEKMEKSWN"
     gene            complement(4579..4956)
                     /locus_tag="TVW11_001261"
     CDS             complement(4579..4956)
                     /locus_tag="TVW11_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1365359.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(5008..5193)
                     /locus_tag="TVW11_001262"
     CDS             complement(5008..5193)
                     /locus_tag="TVW11_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1365360.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            5309..5644
                     /locus_tag="TVW11_001263"
     CDS             5309..5644
                     /locus_tag="TVW11_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1365361.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            5807..6274
                     /locus_tag="TVW11_001264"
     CDS             5807..6274
                     /locus_tag="TVW11_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1365362.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            6289..8043
                     /locus_tag="TVW11_001265"
     CDS             6289..8043
                     /locus_tag="TVW11_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1365363.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKKVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            8040..8210
                     /locus_tag="TVW11_001266"
     CDS             8040..8210
                     /locus_tag="TVW11_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365364.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            8203..8469
                     /locus_tag="TVW11_001267"
     CDS             8203..8469
                     /locus_tag="TVW11_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365365.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEALRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            8503..9723
                     /locus_tag="TVW11_001268"
     CDS             8503..9723
                     /locus_tag="TVW11_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1365366.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAHISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            9701..10366
                     /locus_tag="TVW11_001269"
     CDS             9701..10366
                     /locus_tag="TVW11_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1365367.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            10391..11578
                     /locus_tag="TVW11_001270"
     CDS             10391..11578
                     /locus_tag="TVW11_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1365368.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVAPDTDGIKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSASGKVFLGKPVFVLSDDVIGKD
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            11723..12025
                     /locus_tag="TVW11_001271"
     CDS             11723..12025
                     /locus_tag="TVW11_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1365369.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            12022..12369
                     /locus_tag="TVW11_001272"
     CDS             12022..12369
                     /locus_tag="TVW11_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1365370.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            12366..12743
                     /locus_tag="TVW11_001273"
     CDS             12366..12743
                     /locus_tag="TVW11_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1365371.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            12740..13165
                     /locus_tag="TVW11_001274"
     CDS             12740..13165
                     /locus_tag="TVW11_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365372.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLINVRKYRYFDFY"
     gene            13181..13771
                     /locus_tag="TVW11_001275"
     CDS             13181..13771
                     /locus_tag="TVW11_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365373.1"
                     /translation="MGKVKFGLRDFQYAVLGDDDQLKTKTGGIKSLPGMKSAKLDITN
                     ELVTVAADDGPYVVLSGGITETKLEIEVLDLTSDARKDFFGIKEEDGIEKYNKELTPN
                     DVACMFRTSDENGKAIWIGLLKGKFNIPGMEMQTKEGAPDPKSDTVTGNFVSRGKEGD
                     VIVIGRESASGFKLEKFKEFVFAGATDIKKGENFEM"
     gene            13823..14149
                     /locus_tag="TVW11_001276"
     CDS             13823..14149
                     /locus_tag="TVW11_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365374.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            14197..14346
                     /locus_tag="TVW11_001277"
     CDS             14197..14346
                     /locus_tag="TVW11_001277"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365375.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            14359..18018
                     /locus_tag="TVW11_001278"
     CDS             14359..18018
                     /locus_tag="TVW11_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1365376.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRSLATETSVFTRFGKAAERIGGKMKSFGDSVAGVDAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIYLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDDLGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIVKWGLIAAAAGPALSIFGKGVGIIGGTIQAMGKMSRGLGTLSGWLRTFRTGA
                     VAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGIKVSQVQANELQRFKNKVDEANLAMTTFGVRSANNLDKIKTSFKALADEIEALQNK
                     KLKKDLKLAEKLGLSQETIEEIRRQADQTVATVRGMSDKVVDIYRRAKEERRSLTEEE
                     KTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKKAQEVAQKMIES
                     ENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTAKMESLGERYLKI
                     RKKLLEDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTKISMQDMTSSF
                     RASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALTPQQKELLAK
                     NLTQDPTLSAQQAIDNVKQRVPADVKASDKTAPDVASADRAVNRPKQKGPAIIRAQDN
                     ASSVASGVIGWLNSIPRTVTSTITTIVRKITGHKTGTDYHPGGLAMVNDQKGPLYREL
                     ITLPTGESFIPEGRNVILPLPRGSKVLRASRTKQLFSHYANGIGFNDTKIASLTTRLK
                     SVQDKGQVIVNTDPQLAELIKLLKDRDNRNVTNNYTLNATNRSNSDDMFNQENMRRLL
                     RELAYYTNGEKGRLA"
     gene            18018..18725
                     /locus_tag="TVW11_001279"
     CDS             18018..18725
                     /locus_tag="TVW11_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365377.1"
                     /translation="MRYIEFNGKKSDSFGLLLERERSIKSTSNDVDLIEVDGRDGVLL
                     KDNGRLKAIEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGGTLQNLGNVQSKPILKIKGTGN
                     GVLTINGFETGLENVQGELIIDMERHLVYKDILSAWDNIVRTERHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            18722..20863
                     /locus_tag="TVW11_001280"
     CDS             18722..20863
                     /locus_tag="TVW11_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365378.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVRVTRERNGNYSLYIKYP
                     LDGVFASVFKEELKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEQEQPEEQLVTLPEFILDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIDQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQRELDERNQKELEEFRETLKNLSL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDPNRVKKIDEDFIEVEANDGGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKL
                     VLIPTKAKMEAQTFNLSKDKEVISVYPLSYRAVLTGDWYKSKQIELNAAEVQNLALEM
                     SYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            20863..>21536
                     /locus_tag="TVW11_001281"
     CDS             20863..>21536
                     /locus_tag="TVW11_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1365379.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPQGLSGDRGPIGQTGPQGKQGVSVQSASVDSEGYLTVLL
                     DNGQSFKSDSSLKGSKGDTGPKGADGKMTFEQLTPEQKQQLKGDKGDPGPKGDIGPRG
                     ATGPQGPKGEPGINGMDGPRGATGPRGLQGPLGKDAVLPDDVVRRGELAAYLLRSEYK
                     AKGSGSG"
BASE COUNT         7286 a         3595 c         4917 g         5738 t
ORIGIN      
        1 ttagtttatt ttgacaatat gttggacgaa gaatataagt ttaaaacaga aaaagatgca
       61 tcgaaatgcc atgatcaatt gcgaaggaaa taccaaggtc agcgtttata taaggtaaaa
      121 atggaggagg tggaagaaga ggtaatcata actaacttca gggaggttga tcatgactaa
      181 agacgacttt ttaacaggtt ttgtacttat acttttagct gcttgcattt ttgctgtggg
      241 atttgcgatt gggcatgatt atagcagtga gcactacgag caaaaaatca cagatttaca
      301 aatacagctg gtaagcacgc agcagcagct taagcaatct cgtgagcaaa atcagagcca
      361 gactaaaagg attgcgaatc tgaccgggaa tggaggataa aaaacactac atggaaataa
      421 aatgtggaaa ttgcttagaa ttactaacag agttaactga tggatcaatt gatatggtga
      481 taacagaccc gccatataac atatcagtaa aaaataactt tgctacaatg gggcggacag
      541 gtatagattt tggtgattgg gataaaggtg cggacttatt aagttggatt gatattgcaa
      601 gtcgaaaatt aactaaaaat ggtggaatgg tgatctttaa tgattggaaa aatttaggag
      661 atattgcaag acattgcgaa aaaacaggct tagcagtaaa agatattttc cgttgggtaa
      721 aagataaccc tatgccaaga aatcgagata ggagatacat tacagatagc gagtacggga
      781 tatgggtcgt ccgaaaaaat tccaagtggg tatttaatcg taaatcggaa aaatatgata
      841 ggccagaata tcgctatcct attgtatcag gagcagagaa aacacagcac cctactcaaa
      901 agccggtagc cctgatgagg gacatcatta cgcgacacac aacaaaaagg gctgttgttt
      961 tagacccttt tatgggcagc ggatcaactg gagtagcttg tctactgacg gagagagact
     1021 ttattggata tgagctaaat aaagattact ttaatatcgc aaacaaaagg attgctgagt
     1081 tgactgggaa tggtggatga gatgttaaga gtatttgaag cttttgcagg tattggtacg
     1141 caacgcatgg cattgcgaaa cctcgggata ccacacgaag tagtagctat tgccgagatc
     1201 gacaaatttg ccattaaaag ttatgaggca attcatggcc cagtaaataa tctaggtgat
     1261 attagcaaga ttaatcctga cactattcct gatcacgact tatttactta tagctttcct
     1321 tgtcaagaca tttctgtggc agggaagcaa gctggtcttg atattgatag cggtacacgc
     1381 tcaggattgc tctgggaatg ccaaaaagtt atagtggcta aaaaaccgaa atatctatta
     1441 atggaaaatg taaaaaatct cgtaggcaaa aagcataagc caaattttga taaatggctt
     1501 gattggctag agagtcaagg ctacacgaat gactggcaag tgctaaatgc aaaggattac
     1561 ggtgtcccgc aaaatagaga gcgtgtgttt tgtgtgtcga ttttaggtga gcataaacct
     1621 tatattttcc cagaaaaaca ggaattgacc atcagactaa aggacatttt ggaagatgat
     1681 gttgatgaaa agtattattt aacaacaaac aaagcaaatg aattattggc cacgattgtc
     1741 cgagaaaatg atgtttctga aagagttgtt gtagatagta cgataaaaaa accaaaaata
     1801 aaaaatgtaa tgaacgctgt aataggaaga tatgatgcag gcatccgaaa tcaacaatcg
     1861 gttggaggtg ctgtcattga gcttattgaa taaaaatgca acaaaaaaag gctacttagt
     1921 agccgatgat ggggacggaa tagatactgc ttatccagat agcaaaacga ggaaagggag
     1981 agtgcaaaaa aacatgagcc atacgataac gacagatgat agtaaggcct ttttgattgg
     2041 cgcaagtcgt gggagagacc ccgaaaaccc aaacgatagg tcagctggaa accaaaacct
     2101 acaacaaaga cttgaaatca acaaaaatgg cacaagcaat acaattacaa gtgtccaaaa
     2161 agataactat gcggttgaat tcccagatta ccgcatccgc aagctaacac cgctagaatg
     2221 ttggcggttg atggggtgta gtgatgagga ttttgaaaaa gcacagtctg tcaatagcaa
     2281 tagtcagctt tacaaacagg caggaaacgc aattgtggtt gatgtgctag aggcaatatt
     2341 aaagcaatta tttttaaccg aggcgcaaaa tgaacattga agaagcgaag caaaaattac
     2401 ataacatggc atatagagat ttacaaacta agccgtatga tttgaaactt gctgatgtta
     2461 ttcagattct taatcaaatt aaactcgaca aacctcaacc agaaattcca cagtttgtcg
     2521 ctgactacat agatgatatg cacaaaaacg cacgtacatt gagatacgct tttaaataca
     2581 tggaaagtaa cataaaaatg cacaaatggt gtgttttcga aaagcaagaa acgtttgtta
     2641 atgctttttt atacggatat acaattgaaa aagagaaact gtacactgtt gagataccaa
     2701 atccgaaaaa cggtattgcg cataggcaca taatgctggt taagacaact gacggaagag
     2761 tagttttgtc tgaagtagta gactcacaca tacatttgag agatgattta agactcaccg
     2821 agtcagaaat ccgcaaagac ttcgattggg cttggagaga ggagtttcct aaagaggtga
     2881 cggaatgatg aatgaaagag aattaaataa attgatgaat tacgacaaaa agaaaagtga
     2941 tttaaaaaaa cgcctgatta taggatttac cctattgcca atcagcatcg tattgtctgg
     3001 atttgttatt aaatacggtt ggaataatat tttgtcaaca attgatggcg tcccacctat
     3061 caatttacca caagcgatag caattgatgt gctagtaagt tttatcattg ccaagacaaa
     3121 cgcagaagga gattttgcca cagaagttgg cagagctttt atttcgccgt taatgacgtt
     3181 gttattgttt tgggtagtga ctttgtttat gtaatgttta gaggtaacag atgactgaag
     3241 aattaggagt gttgcttgac aaggaaggag ttgaatacgt aaaaatggta tttgatgatg
     3301 gctttgtctg gacgatacgc aacccactaa acgctgcgtt gcttaaacgc caagatgcag
     3361 agcagttccc gcagtttacg tgggtgccac tgacagattt ataaccccac gcaatggctc
     3421 tgtgggatta cgtgccagga accacgttga aagcgactta gacaccttca tttttatcag
     3481 ccttgcggat tgtcaaaggt tcgtaaggtg tagaccgaaa ttaaacacag aaggatgtga
     3541 tgacaatctc cttacaccca aaaaatctaa cgctggttac cggtcaccag ctattatcca
     3601 aggcgctaat actgacatcg tgcgcctgtg tcaaaataaa aaaaggaaga gagggctttt
     3661 ctccacaaaa aaagacgtcc atgcgaacgc ctccttggtt atatctgtta acaccattat
     3721 accacactga gggggctttt atgacgtttt ttcccgagat tgatatccaa aaaacaaaat
     3781 ccaatgccaa gcgtaaattg aaagagtatc cacgctggcg gcggatagct aacgatgtag
     3841 atactcaaaa agttacagct acttactcat ttgagccaag gcaacctcat ggagtcccta
     3901 gcaagcctgt tgagagacta gcacttaatc gtgtatcagc ggaacaggaa ctggatgcga
     3961 ttgagagagc ggtcaacggg atatttgatc cagagtatag attgatactg attgacaagt
     4021 atttgctcac atatccaaag actgattgtg atatttatac aaaacttggt tacgagaaaa
     4081 gtcagtacta caacatgcta gataatgctt taatgtcttt ttctgaacta tacaaagagg
     4141 ggatgttgct tgtcgaaaaa atggaaaaaa gctggaatta atatggaata attatgtact
     4201 ttatatataa atattcatgt tattatagta ctatgaaata acaagaagag ataaccattt
     4261 taccaactga ctatttattt agtcgctgac tttaactacg atcaaacttg ttattttatg
     4321 tatgtgggac gtgcgggttc gaatcctgcc gtctcaatca gcgcccagaa gaggcgcgac
     4381 cccatacccc tttaaaggca gacacgttct gatgtgtggg tttttatgat taaccgcaag
     4441 ttcaaaaaca agggtcgcaa ccttgcttgt ggttagtagg gacaacggtt gtaagtcggt
     4501 tcgattccga ctgttcctgt gctagtcatc acatcgtgat ggctttttat tatgcaaaaa
     4561 agaaccacta agtggctctt atgcttgtag ttttaattca agtgcctctg tgaggacttg
     4621 cgagaaattg agattttcat cttcggctgc tttgtttaac cactcaggga tagtcacgtt
     4681 cttacgtact tttttagagt ggtatttttt catgtaggca atcatatcga tgccgattaa
     4741 agcaatatca gaatcacgat actgttcttt taagtcggaa acggagctag cctttggata
     4801 gtcagtatag tcttcaagag caaagcctaa gacttcgaca gccatttcgt aagcttcttg
     4861 aaagtcttta ccttgagtaa ttgcttcagg tacatctgga aatgtaacca tgatatagtc
     4921 tgtgtcttgt gtgaatgtag ctggatagat taacataatg attctccttc gatcactgtg
     4981 agataagcaa accatctggc aagcggatta ttttaaaccc gcctgcttta gaatggtatc
     5041 ttcaaggcct tttccgaggt ctttgttgtg tagaggaaca atggtttgat gtccgttatt
     5101 atctcggaat tttttgtgac ttccgttttg actgacttca tagaacccat tcttttttag
     5161 cagttttatc atctgctttg gggtcattgg catattgctt acctcacttt ctatacttat
     5221 attatacacg caataaacat ggttgtcaat aggtatgcgc aaaaaatgcg tatttttgtt
     5281 ttctattttt tattatggag gttagggtat gaggccgcag aagttaacaa ttgcgggtgg
     5341 cagacgaacg actgttgact acgatgatag gtcagctgag tatcgtgact ataatcgtaa
     5401 cagatggaag tatgatagga agactaagca gttttataac tctaagattt ggagagagac
     5461 aagtaagcaa gtcttattgc aaagtgatta tatctgtgca atgtgtggtg gagaagcaac
     5521 gatgactgat cacattgtct cagttaagaa agattggaat aaaagattag attggaataa
     5581 cttgcaagca agttgtaaag cttgtaacga ttgtaaagca ataagagaga gacggaaaac
     5641 ctaaacgtac ataaaaagta acatacgcaa tcattgttcg ggaaataccc cgcctatttt
     5701 ttaacggggc tatattgttc ggaaacttaa gaacgcgccc ttttctgtgc aaaaaaatcc
     5761 ctttttgaaa tttttgaaac tgtaaagttt gtgtaaagga ggtcttatgg gaagaaattt
     5821 aaagctagtt gaaacgacaa aaaagcatct tacgaaagaa gaaaaaatag tgcgagaaac
     5881 cgcgcaaaat aaggcgtctg acggtcttaa aaagttgcaa aagacacctc ctgaacactt
     5941 taataatgta gctaagtacg agtataggag aatcatagaa gacctccaaa acctacccct
     6001 aagaaatctc gatagagggc tattagagtt atattgcaca tggtatgcta tctacaaaga
     6061 aacaagtaga aaactagatg aggttggtta ttttacgaat gatccagaca aaggcattat
     6121 tcctagtccg cttattttaa cattggaaaa agccactgcg aatattagaa gtagtgccag
     6181 tcaattagga ctaacggtag atagtcgcat gaagatgttt attccgaagg aagaagaaaa
     6241 acctaagagt atatttgata aatttggagg atagagagaa agggggtcat gacaatagaa
     6301 tacgattatt cagcaatcgg cgacatctat aaagatgacg ctttttatta tgcaaaaaag
     6361 gtcgttgatg aagagattaa agcaagtaag aaggtcttta aagcttgtct aagacatttg
     6421 aatgacctta aaaaaataga tgatgataat tttaaattta tctatttacc aaaaaaagca
     6481 attgacccca taatttttat tgagctattg ccagacgtta agacgggaaa gccttatcct
     6541 ttagcgatgt ttcagaagtt tattatcggg aatttatacg gatggcgaaa gaaaacagat
     6601 cattccttaa gacgctttag aaaagctatg atttcggttg ctcgtaaaaa tggcaaaaca
     6661 attctgatag ctggtatctt gctttatgaa tttttgtttg ggcataatcc atctatgagt
     6721 agacaattgt tttgtacagc taatgaccgt acacaggcta aaattgcttg ggacatggca
     6781 aagaagcaac tctcatcttt aagagcaaag gacgctgatg tcagaaaagc cacgaaaatt
     6841 gttcgtgatg agctgaaaaa cttacatgat gaatcttata ttagggctct tagtcgagat
     6901 actggggcag tcgatgggtt cgagccttac gttggcgttt tagatgagtt tgcggcatca
     6961 aagacaaacg aaatgttaga gcttttagaa tccggtcaag gtcagcttga taatccgttt
     7021 atcttgatta tctcaacagc tggtatggat ttgaatgtcc ccatgcacac aattgagtat
     7081 ccgtacatca ctaaaatttt agacgaagaa attgtagatg atggctattt tggatatgtc
     7141 gcagagcaag acaacgaagg tgaaattaaa gatgaatcaa attggataaa atcaaatcca
     7201 atcctcgagg ttgaagcttt gcacgataag ctaatggatt acctgagaac gcgtcgtaga
     7261 gtgtctcttg aaacaggtga aattaacaag gtacttatca aaaactttaa catgtggcgg
     7321 cagtcgagtg aggaatcata tattgataag caatcttggg aacttgctcg tattgataaa
     7381 cccgacacac ataaacgaag ggtctggcta ggtgtggacg tcggtcgtgt tagtgactta
     7441 tttgctatta caccagttat tatgatggac gatttttggt atattgacag tttttctttt
     7501 gttgcgacaa agtatgggtt aacggctaaa gaaaagcgtg atggtgtgtc ttacagtaat
     7561 ttagaacgtc aaggctattg cgagataaca acattagaaa gtggggttat tgatgatgag
     7621 agagttttag aaaaaataga ggagatggtc tattcgaatg actgggaagt taacggaatc
     7681 tgttttgacc cttaccaatt tggaacgctg cttacgatga ttgagaaaag gcacccagaa
     7741 tggcctctca tagaggtttc gcaaacgaca atggttttga acatgccaac aaagcaattt
     7801 cgtgatgatc tcaagaatgg caaaataaag cactctggca atccattgct aacaatggct
     7861 gttaataacg cttatatcaa gactgataac aatggcatga ggattgataa gaataagaat
     7921 agcaataaga tagaccctct ggacgctgct ttagacgggt atgcagtttg ttacttagag
     7981 ccatttgacg gctctggtta ctggacaagt gagaaaattt taggaggaga gacactgttt
     8041 tgattggttt tattttaaaa aacatacata cattaatctt gttagctgga ctaggtttat
     8101 tgatgtatgg gttgtttttg tttggtgata aagttggttt tatcgctagt ggtcttattt
     8161 taattttttt agctatctat gtagatagcg taggaggaaa acatgaataa acgcattaag
     8221 aaaaaacgta aattggaaac agcggttgtg atgcttgttg cagaaaatgc tatgcaagct
     8281 gaagcactca ggaatcaaaa cagacaaatt gcagagctga gatcgattat acaacaaaac
     8341 gcccaagcga caaatagaga gtttgcagca gttaaatcag cgacgctaga caaccaagca
     8401 gccattaaga aaattgggga tgaggtttat tatatcaagc aaaattataa gcgcaagtgg
     8461 cggaaataga tgttaatggt ttagaaagga ggtgagaaat cgatgagttt ttttcaacct
     8521 ttgggcagtt caaaggtgtc ctatgatgac tatgtatcat ctgttttagc tggcgatgtc
     8581 tcccaaaaat acttaggagt gtcggctttg aagaatagcg atattttaac agcaacgtct
     8641 attatagctg gggatattgc taggtttccg cttgttaaaa aggatgttaa tggggacatt
     8701 atccatgatg aggatattaa ttatctttta aatgttaaat ccacaaaaaa tgcgagcgct
     8761 aggacctgga agtttgctat ggcagtaaat gccattttga ctggtaattc tttttcgcgt
     8821 attttgagag atccaaagac taaccaagct ttgcaattcc aattttacag gccgtcagaa
     8881 acgactgttg aggagacaga taaccacgag atagtttata cgtttactga tatgttgaca
     8941 gcaaaacagg ttaaatgttt tgcccatgac gttatccact ggaagttttt tagtcacgat
     9001 acaattttgg gaaggtcccc gctactgtct ttaggtgatg agattgattt gcaaaccggc
     9061 ggcatcaata ccttaattaa attcttcaaa gatggttttt ctagtggcat cttaaaaatg
     9121 aaaggtgctc atataagcgg tgaagcacgt aagagagcca gagttgaatt tgaaaaaatg
     9181 cgcgagggtg caattggtgg tagtccttta gtattcgatg atacgcaaga atacacgccg
     9241 cttgaaatcg atactaacgt attgcaatta attacaagta acaatttttc aacggcgcaa
     9301 atcgcaaaag ctttgcgggt tcccagctac aagcttggtg ttaatagtcc aaatcaatct
     9361 gttgcccagt tgatggaaga ttatgtcacg aatgatttgc cattttattt tgatgctatc
     9421 acaagtgagt taggacttaa gacgctaagt gataaggata ggcgtttgta tcgtatcgag
     9481 tttgatacac gaagcgtcac aggtcgcaat gttgatgaga ttgtcaaatt ggttaataac
     9541 caaatcttga cgcctaacca aggcctcgta gagcttggta agcaaaaatc aacagatcca
     9601 aacatggata ggtaccagtc tagtctaaac tacgtctttt tagacaaaaa agaagaatat
     9661 caagacaagg ttggtatcaa agggaaagga ggtgaggtaa atgccaaaga ggataaatct
     9721 taaaggacca ctaattgcaa ataactctca agaagtttac gactattacg gaatggaagc
     9781 agcaagtgct aaaagtatca ttgagcaatt tcctgaagat aatagcgata ttgttttgga
     9841 agttaattca aacggtggac ttgtgacagt tgggagtgaa atctataccg ctttacgaaa
     9901 ttacaaagga aaagtaactg cagaaattac tggcatggct gcaagtgcag catctgtggc
     9961 tgttatgggt gcggataagg ttgtcatgag tcctacagct caaatgatgg tgcataaagc
    10021 actctttaaa tgggtgtctg gtaatagtga tgacctagac aaagcttcta atgccttaaa
    10081 atcaagtgat aaagctattg tgagtgccta tgtcgcaaaa acagggttat cagaagatgc
    10141 aatcatggat ttaatgcgaa atgaaacgtt tatgtccgct caagatgccg tagaaaaagg
    10201 ttttgcggac gaagttatgt cttttgaagc agttgctagc attgataatt ccatgttgcc
    10261 gcaagctgtt attgatgact attacagaag taggaacaaa cgaaaacaag agattagcaa
    10321 catgttacta gaaattgaaa aagaagaaat tttacgaggg ctataagctc tttttttatt
    10381 ggaggaattt atgttcgaag aaaaaatcaa agaaattaaa gcgaatatcg ctaatttaaa
    10441 ccaagctatt gctactaaaa caacagaagt aaaaaatgct ttggaatcag atgaccttga
    10501 aactgctcgc tcaattaaag cagaaattga agaagctaaa gcaaacctag cagaagcaga
    10561 aaatgacttg aaattgtatg aagctagcat tgaaaaaggc ggtgcagaaa atactggagg
    10621 aaaagaagtg ccacaagaaa ctaaaacata ccgcgaaagc gttaacgaat ttattcgttc
    10681 aaaaggaaca gtaactaatg aagctttgcg ttttgaagga aaagatgaag ttcttattcc
    10741 gcttaatcag acaacaccag tcgctcctga cacagatgga attaaaaaga cagacgtgaa
    10801 acctgtttct agcgaagaaa ttctatacac accagctcgt gaagttaaga cagttgttga
    10861 tttgaaacaa tttactagca tccacccagc taagaaagca tctggtaaat ggccggtatt
    10921 gcaacgtgct acagaaaaaa tggtaagcgt tgaagaattg gaaaaaaatc caaaactagg
    10981 caaaccacaa tttaaaaacg tggagtggga agttaaaact tatcgtggag ctatcccgtt
    11041 atcccaagag tcaattgatg atgcagatgt agatttggtt ggtattgttg ctgaaacaat
    11101 cggtcaaatg aaagttaata caactaatga tgcaattgct aaagtcctaa aaacatttga
    11161 ggctaaagct ggtgtcaaaa cattagatga catcaaaaaa atcctaaatg tagatttaga
    11221 tccagcttac aatgtgtcat ttattgtatc tcaaagcttt taccagtcca tggatacttt
    11281 aaaagacgaa aatggccgtt acctacttca agattcaatc acttctgcgt ctggcaaagt
    11341 gtttcttgga aaaccggtat ttgtcctatc tgatgacgta attggtaaag actcagcttt
    11401 tgtcggagat tttaagcgcg gcgtgttatt tgctgatcgt aaagatttag ggcttcgttg
    11461 ggcagataac gaaatttacg gtcaatactt gcaagctgtc cttcgctttg gtgtcgctaa
    11521 ggtagatgac aaagctggat actatgtgac attcaaacca gaacaattgc cctcataagg
    11581 ccactgaaga agtggcgaaa ccaactagca aaagcactgt cgaggagatt aagcgctatt
    11641 taacaagcaa gggaattgac tttaatggga aaacattaaa atctgattta ttaaaacttg
    11701 caggcgttga agaggtatag ctatggctgt atcaaaagag ttattagaca gtgtaaaact
    11761 ctattgtaaa attgactttg attttgatga cgacatcatc aaagaaatga ttgaatctgc
    11821 tcaagaacaa atctgttttg caatagaaga cggttctact cctgaaaagt tcaaaggtca
    11881 cgctaaattt aatttagctg tcaaaaagca agtcaaggaa gagtatgacc atcgcggttt
    11941 gtctgcggat agttttcgct atccgttggc aaatggtgtt ttaaacatta tccatcaatt
    12001 gcgattgaga ggtgatgatt cgtgattaca cgcaagatga acgtcaggat aacgattttt
    12061 agccaatcag gcgggcaaaa tgaagatggt gaagtagtat ctgctgtcag aaaggacttg
    12121 tatacttgtt gggcagaagt gctaaaaacg cagttgagag attttaatta tcaatcaaag
    12181 tatcaaaacg ctagcaattt gccaacaaat aaggatacta aggttttttt aattaggtat
    12241 aaccctgaat tatctataga taacacgatg tttgttgagt ttggcaagcg catttataag
    12301 atagataaaa tcgaatctga cgaatctggc aaagatatta tcatgataag tggagtaagc
    12361 atgtcatgac aaaaggttta gatgaaatat tggctaatct gacaaagctt gaagtaaaag
    12421 caccaaaaac cgcaaaagca gcagtaactg aagttgccaa agaatttgaa aaagcactta
    12481 aagcaaatac ccctgtttat gagattgaaa cagatgagcg gctacaggaa gataccgtta
    12541 tcagtggttt taaaggagct aatgttggaa ttgtatccaa ggaaattggc tatggcaaag
    12601 cgactggttg gcgtgcgcac tatcctaacg atgggaccat ttaccaacgc ggacaagact
    12661 ttaaggaaaa aaccatcaat cagatgacac caaaagctaa acaaatctac gcagcaaaag
    12721 ttaaggaggg actaggactt tgattgctga aacagcagct tataaattat taagtaacga
    12781 taagacgcta aatgagttgt tggataggct cagaggcggt ccttttaaaa atgggtttaa
    12841 gcaaggcata tttacttatg atattccaga taacccagtt gacttgcgta aggtagattt
    12901 agcgcctttt atgcgaatca acacaacatt agacggtcct gctgattatg cagatgatga
    12961 gatactgtgt aacgagcaac ggatcaccat caatttttgg tgcaaaacag cttctgaagc
    13021 tgaccaaatt agcaaatgta tagatgatat tttaaaaaaa ggcggttttg aaagatacac
    13081 cgcaaacgaa aaaccaagat ataaagatag cgatattgac ttactgataa atgtaaggaa
    13141 ataccgctat tttgattttt attaaaagaa agaggaaaaa atgggaaaag taaaatttgg
    13201 actacgtgac ttccaatacg cagtactcgg agatgatgat caattaaaaa caaaaacggg
    13261 aggtatcaaa tcactacctg gcatgaaatc agcaaagctt gatattacaa acgaattagt
    13321 gacggtagct gctgatgatg gtccatacgt agttttatct ggaggtatta cagaaacaaa
    13381 acttgaaatc gaggtgttag acttaacatc tgacgcacga aaagacttct tcggaattaa
    13441 ggaagaagac ggaatcgaaa aatacaataa ggagctgacc cctaacgatg ttgcttgtat
    13501 gttccgaaca agcgatgaaa acgggaaagc catctggatt ggattgctaa aaggtaagtt
    13561 taacattccg ggtatggaaa tgcagactaa agagggagcg ccagacccta aatctgatac
    13621 tgtaacaggc aactttgtgt ctcgtggaaa agaaggagat gttattgtta tcggtcgcga
    13681 aagtgctagt ggttttaaat tagagaagtt taaagaattt gtgtttgctg gtgcgacaga
    13741 tattaaaaaa ggcgaaaact tcgaaatgta acaatcaggt tggatttaaa atccaacctt
    13801 ttatttttga taaggagtag atatgtacga aattacctta aaaaaaggtg gtgtagataa
    13861 agttttttca aaggacttta ttaacgttga ggataatttg ttggctgttg agcatcaagt
    13921 tagacaaagc gctgtgttta gcgatgagaa aagacgctta gattctaaag cgcatagaaa
    13981 acttaacgaa tcttacttgc aaatgtttgt tgatatgtac gcaggtcaat ttacagtcga
    14041 tgatttaaag caatctgaca tgagtgtttt aaatacactt aatgacctgt acattgcagc
    14101 actcggtgga gagcaagagg aagacgaaag cgaaaaaaag gaacaataac cccacaagag
    14161 gctaaagaaa acttactctt gtggatacag agccttttga aaaacggtta taccatttta
    14221 gatattaaaa aaatgcgctt atctgatatt gaattgatgg tacaagcgct agaaattgaa
    14281 actgtcgaaa aagaagaagt gattgaaacg accttggata aggcattccc attccttttc
    14341 ggctagaaag gaggataaat ggggaatata ggtgatttag tagcaacggc tacactagac
    14401 atatcaccat ttatgtcaaa cacaagaaac ctaaaaacct acatgaaagg cttagataac
    14461 tcgttaaaag cagttgaaaa gagctttcaa gggcatggcg ggcggatcaa aggtcttaaa
    14521 gcggtctatg ctgaaacagg tagtgcatta aaaggttacc aagaattact aaaaactcag
    14581 tcgcaaaaat atagcgacct aaaaaaagag ataggtgatg ttaataacgc tactgctgag
    14641 caaaagcaaa aattgattgg cgctaaatca gccatgttgg agactgctgc gaaagtcaca
    14701 gaattgcaaa acagattacg atcgttagcc actgaaacta gcgtttttac aagatttggt
    14761 aaagctgctg aaagaatcgg cgggaagatg aagtcattcg gcgattcggt agctggagtt
    14821 gatgctgcat ttacaagagg agtcaccgct ccgattgtag cgggcgctgg ttatgctatt
    14881 aaagcagctg ttgactatga aactgcattt gctggtgtta aaaagacagt tgatgagacg
    14941 gcgacagtat cttatgcgaa gctatcacag ggtattagac aaatggccaa agagttgcca
    15001 gccagtgctg ttgaaatcgc tcatgtcgcg gaggcggcag gtcaattagg agttaagaca
    15061 ggagatattc ttagtttctc tcgtacaatg atttatttag gagagtccac caatttatcg
    15121 gcagaagaag cggcgacgtc tattgctaaa attgcaaaca ttacaggtct ggcttcatcg
    15181 gagtattctc gctttggtag tgctgttgtc gcgttgggta ataacttcgc aacaactgaa
    15241 agagacatcg tagcgatgac taatcgcatt gctgcgtctg gtaagcttgc gggattaacc
    15301 aatcaagaga tgttagcttt agcaacagca atgtcaagcg ttggtataga ggcagaagct
    15361 ggtggtacag caatgactca atcattgtca gctattgaac gtgcagttgc atctggagga
    15421 gataatttaa ataaatttgc tcaaattgcc aatatgtcat ctgctgattt cgcgagagca
    15481 tggaaagaga agccaattgt tgcattgcaa gagtttatta aggggcttgg ccagcttgat
    15541 aaaaaaggtg aaagtgctac aaaagtgctt gacgacctcg gattaagcgg tatccgccag
    15601 tctaacatgt tgaaatcttt aggattagca tctgagactt taggcaaggc tctagatacc
    15661 tcaaacaaag cttggcaaga aaacactgct ttaactgacg aagctaataa acgctatgag
    15721 acaacagagt ctaagctaaa aatgcttaag aatgaagtta atgatgtagc tattgaattt
    15781 ggtggccctt tggttgacgc tctaagaaat gggctcgaag caggaaaacc aattattcaa
    15841 atggcagcag atttagctaa gcaatttaac tcgcttgaca aagagcaaca acaacaaatt
    15901 gttaagtggg ggcttattgc agccgcagct ggtccagctt tatctatctt tggtaaaggc
    15961 gttggcatta tcggaggaac cattcaagct atgggcaaaa tgagtcgagg gttaggcact
    16021 ttatcaggct ggttgaggac attcagaact ggagcagtag cagctagtgc aggagccgaa
    16081 gctgccacag cttctatggg cggaatggct ggcgcggttg ccttattaag taatcctgta
    16141 acttggggtg tgctgttagg tggtgcagcc attgtgggta taggtttaat tgctgatagc
    16201 atgtataaag cccaaaaacg cacagaagag tggggaatta aagtgagtca agtgcaagcc
    16261 aatgaattgc aaagatttaa aaacaaagtt gacgaagcta acctcgcaat gacaacattt
    16321 ggagtcagga gtgctaataa tctcgataaa atcaagacat cttttaaagc actggcagac
    16381 gaaatagagg ctttacaaaa caaaaaactt aagaaggatc taaaactagc cgaaaagtta
    16441 ggtcttagtc aagagacaat cgaggagatt aggcgtcaag ctgaccaaac tgtggcaaca
    16501 gttagaggta tgtctgacaa agttgtagac atttaccgaa gagccaaaga agaaagaaga
    16561 agtttgactg aagaagaaaa gactgttgtc actaaaaatt tgaatgacat gatccagact
    16621 gagttatctt tgatgaacta ctctaaaaaa gaaaagatcg ccattttgaa ggcgatgaat
    16681 ggagagattg aaacgcttaa ttatgagcaa cttaaaaaag ctcaagaagt tgctcaaaag
    16741 atgatagaga gcgaaaacaa gacttataaa aagagacgaa gtaatctcaa agaaatgtat
    16801 gacaatatca aaggagactc tgaaactgct gtgagagcca gagaggagat tcacagacag
    16861 ctggagacct tggaagatag tcatacagca aaaatggaga gtttaggaga aagatactta
    16921 aaaattcgta aaaaacttct ggaagaccca gctttagatc cacgagttaa gcaggctatg
    16981 attgatagct tagacaagga atttgaaaaa ttaggattat ctttcgaaaa gttatctaaa
    17041 aggagtgaag aggctagctc taagaccaaa ataagcatgc aagacatgac aagctcattc
    17101 agagcatcga taggcgaagc cattagttca ttgcaagggt gggacaatct tacgccgcag
    17161 gaaaaacaat tgttgataga tgggaataag gctgtcagtg agatcctaaa tagtaaaact
    17221 ttacttgagc aatggcaagc gctgacccct cagcaaaaag aactgttagc taaaaatcta
    17281 actcaagacc caacgttatc agctcaacaa gcaatcgata atgttaagca gcgagtgcca
    17341 gctgatgtta aagcctcgga caagactgct ccagatgtcg cttctgccga tagagccgtt
    17401 aacaggccta agcaaaaagg tccagctatt attagagcac aggataatgc tagtagtgtt
    17461 gctagtggag ttattgggtg gctaaatagt atacctcgta cagtgacatc gacaataact
    17521 acaattgttc gtaaaataac cggccataag acgggaactg attaccaccc tggcggttta
    17581 gcgatggtta atgaccaaaa aggtcctttg tatagggaat tgatcacttt accgacggga
    17641 gaatccttta tcccggaagg aagaaatgtc attcttcctt tgccaagggg gtcaaaagtt
    17701 cttagagcaa gtcgtacaaa acaattattc tcgcattatg caaacggaat aggttttaat
    17761 gataccaaaa tcgctagctt aacaactcgt cttaaatctg tgcaagataa aggacaagtg
    17821 attgtcaata ccgatcctca acttgcggag ttgattaaac tacttaaaga tagagataac
    17881 agaaatgtca caaacaacta cacacttaac gctacaaaca ggagtaactc tgatgatatg
    17941 tttaatcaag aaaacatgag acgtctccta agagaacttg catactatac aaatggagag
    18001 aaagggaggt tggcttaatg cgatacattg aatttaatgg taagaaaagt gatagctttg
    18061 gtcttttgct agagcgtgaa cgatctatta agtcaacgag taacgatgtt gatttaatag
    18121 aagtcgatgg acgcgacggt gtactcttaa aagacaatgg tcgtttgaaa gctattgagc
    18181 aagactttcc tttttctttg gttggtgacg tggctgtcaa tcagcaaaaa ataagtgaat
    18241 ggttacatgt caagggttgg cacgacttag ctttgtcttg ggacaaggac tatatctatc
    18301 gggctagtgt tgtcaatctt tttgaaatag acgagatact taagcaattt ggtagattaa
    18361 aggttaattt cttaatccac cctatcaaat acctaaaaac tggtaagcaa gaggtgtctc
    18421 tcgttaatgg tggcactcta caaaaccttg gtaatgtgca gtctaaacct atcttaaaaa
    18481 tcaaagggac aggcaacggt gttttaacca ttaatggttt tgagacgggc ctcgaaaacg
    18541 tccaaggaga gctcatcata gatatggaga ggcaccttgt ctataaagat atcctgtctg
    18601 cttgggataa cattgtgcgg acagaacgcc accgcatgcc actatttgat attggtcaaa
    18661 acaaaatctc atggactggt aactttacta tcaccgcagt gccaaactgg ggggttaaag
    18721 tatgatacca gttttatacg aggccaaaga aaccaaattt aggacttttg gccttggtga
    18781 gatcgcagac gcttatgagg taagagttac tcgtgagcgc aacggtaatt actcgctata
    18841 tatcaaatat ccacttgatg gtgtttttgc ctcggtcttt aaggaggagc ttaagattaa
    18901 gtctgatgcc ggccgaagga caaaatggca aacttttgag atcaatcggg tgttgcgaaa
    18961 cagtaaagac cacatcgaga tttttgcaag gcatatctca atgcgcacac aggacatcgc
    19021 tttaaaacca tttgtgagcg ggtctagcat tgacgcagag tcggcactgg aggtttggcg
    19081 ggataatctt gtcggtgatg atacctttga tgttaaaagc gacattttaa cactaggcag
    19141 ctttaactgg gaagttgaca agataggcaa tgcaagaggc gctctcgggg gtgttgctgg
    19201 ctctatctta gatgtttacg gtggtgagta cgagtttgac aatcgcacaa tcatcttaca
    19261 taaacaaatg gggcgtaagg cccctacggt tttggagtat ggccgcaata tcgtcagcgt
    19321 ggaagaggag cgtttgcttg atggcaatta tacctcaatc tatccttacg taagatatac
    19381 gccacaacca aagccgcaag aggaagcctc tggtaagccg cacatcggtg agcaggagca
    19441 gcccgaagaa caactggtga cgctgcctga atttatccta gatggtcagt atcttgactt
    19501 atatgcccaa cgcagaatac agatggttga tttatctagt cattttaatg atgacaaaaa
    19561 agagccgaca gtcgaagaaa tcagaaagct ggctcagaaa tatcttaaag ataacaatgt
    19621 tggcgcacct aaaatcagta tagaggttga ttatatcgac ctgtcacaga cgcttgacta
    19681 tcaagatttt agagttatgg aggaggtcga gctttgcgat attgtaccgc tttactatcc
    19741 aaagtttggt atcacaaccg agaccgaaaa agtcgttgag attgtctatg acgtctatac
    19801 agatagcaat cacacaataa agcttggcac gattgaccaa tctatctcta agagtctgac
    19861 aggtggtgtt acgcagcgga ttgagacgct ggaaaacaac caaaaggtta ttactaataa
    19921 tcaacagcaa tttgagctta atttacccaa atacctcaac gatctaaacg gtaccaagat
    19981 atggtacgaa aaaccagatg acaacgttga gcacaagata ggcgattttt ggtttgagaa
    20041 aaacggtaaa tatcagcgta cctgggtttg ggacgggaat caatgggtaa aaatcattga
    20101 tactgaggat ttaaatccta atcagcgagc ttttgatgag gctatggccg agattgaaaa
    20161 gctaaagcag caccagcgag aactcgacga acgcaaccaa aaagagctcg aagagtttag
    20221 agaaaccctc aaaaatctgt cgctgcccga ggaagccatc aaaaagataa cagaggctat
    20281 caaagttgat gatataccgt caattaaaca gtcgtttgac gacctcaaaa acaaagtcag
    20341 tgagacgagc gagaccgcac gattaaacgc tgagattatc gggacagatg gcaagacccg
    20401 ctacaacaaa aacttattgg ttggcgaccc taatcgtgtc aaaaaaattg atgaggattt
    20461 tatcgaggta gaagccaacg atggtggctt tagacgcggt gagacttaca ccatcagctt
    20521 tagccaaact tgcgagctgc tcaaaaaagt ggctatcacg ttgacgcaag ctaataataa
    20581 gggtgttaaa ttagtgttga taccgactaa agctaagatg gaggcgcaga cctttaatct
    20641 aagtaaagat aaggaggtca tcagcgtcta tcctttgagc tacagggctg ttttgacagg
    20701 tgactggtat aaatctaagc agattgagtt aaatgcggca gaggtccaaa atttggctct
    20761 ggagatgtct tatagagacg tagttgatag caataatgct agtttgattt tggattggtc
    20821 cccaaatcca gatgttattt ttgatggaaa tggaggtagt taatgtcaga gactatatca
    20881 gctatagttg tgcataaaag catgacaaaa aacgagtggg agtctagtga catcattttg
    20941 ccacaaggcc agctcgtcta tgagtctgac acaggccata gtaaatttgg cgacggtaaa
    21001 aatagatatg cagatttgat ctatcaaggt gggccacctg gaccacaagg tccacaagga
    21061 ctaagtggcg accgcggtcc cataggacaa acgggtccac aaggtaaaca aggtgtcagt
    21121 gtccaaagtg catcagtaga tagtgagggc tatttaactg ttttgttaga taacggacag
    21181 tcctttaaat ctgatagcag cttaaaagga tctaaaggag atactggtcc taaaggtgct
    21241 gacggtaaaa tgacttttga gcaattgacg ccagagcaaa agcaacaact aaaaggcgac
    21301 aaaggtgatc caggtcctaa aggggacatt ggtcctagag gcgcaacggg gccccaaggt
    21361 cctaaaggag agccagggat aaatggtatg gacggtccaa gaggtgcaac aggtccccga
    21421 ggactgcaag gcccactagg aaaagatgcg gttttgcccg acgacgttgt tagacgtggt
    21481 gagctagcag cttatctgct acggtcggaa tacaaagcta aaggctcagg atcagg
//
LOCUS       DARYUW010000036        20405 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYUW010000036 DARYUW010000000
VERSION     DARYUW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20405
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(85..1350)
                     /locus_tag="TVW11_001282"
     CDS             complement(85..1350)
                     /locus_tag="TVW11_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1365380.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TVW11_001283"
     CDS             complement(1364..2221)
                     /locus_tag="TVW11_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365381.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TVW11_001284"
     CDS             2564..3856
                     /locus_tag="TVW11_001284"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1365382.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TVW11_001285"
     CDS             complement(3971..4744)
                     /locus_tag="TVW11_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1365383.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TVW11_001286"
     CDS             4869..5615
                     /locus_tag="TVW11_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1365384.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TVW11_001287"
     CDS             5630..6610
                     /locus_tag="TVW11_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1365385.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TVW11_001288"
     CDS             6849..7169
                     /locus_tag="TVW11_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1365386.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TVW11_001289"
     CDS             7194..7502
                     /locus_tag="TVW11_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1365387.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TVW11_001290"
     CDS             7513..8817
                     /locus_tag="TVW11_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1365388.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TVW11_001291"
     CDS             9098..11515
                     /locus_tag="TVW11_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1365389.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TVW11_001292"
     CDS             11530..12198
                     /locus_tag="TVW11_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1365390.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TVW11_001293"
     CDS             12323..13414
                     /locus_tag="TVW11_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1365391.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TVW11_001294"
     CDS             13921..14973
                     /locus_tag="TVW11_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1365392.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TVW11_001295"
     CDS             15002..15580
                     /locus_tag="TVW11_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1365393.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TVW11_001296"
     CDS             15779..16687
                     /locus_tag="TVW11_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1365394.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TVW11_001297"
     CDS             complement(16923..18269)
                     /locus_tag="TVW11_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1365395.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19309..19413)
                     /locus_tag="TVW11_001298"
     CDS             complement(19309..19413)
                     /locus_tag="TVW11_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1365396.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19793..20308)
                     /locus_tag="TVW11_001299"
     CDS             complement(19793..20308)
                     /locus_tag="TVW11_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL1365397.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5781 a         4095 c         4555 g         5974 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggcaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aataactcct tataactatt attcatttta
    18301 attaattaac cagttaacta tatcaatcta tcaaaaaaaa tatagtatgt caacctctta
    18361 aagtgattta atcagaacaa acgtatgaag aaaatcattt ggtgaaaaag aagcttattt
    18421 tagctgaaat agatccatta taaaagaggt gtcgtgaagt aactcaatat tcacctattt
    18481 ttgtcgcaag tattctaata ggaatagaaa aagggcagtt gcttgcaaca actacccaat
    18541 gtaaaaccgt taaagacggt gacagaaaat aactgttaac tgaactacct caaaagttaa
    18601 accaaagatc taaccgttgg atgttggttt gtagagcggt tattttttta ttgttatgtt
    18661 tacaacgact aagctcatca gtgtaaggga aagggacttc catattaaga agtatatata
    18721 catcctagat gagacgtgta atgaatgggt tgaacaaata gttgcttaat tttgggataa
    18781 gggttataat aaaaatagaa aaagggcagt tgcttgcaac aactacccaa tgcagaaccg
    18841 tttgagacgg tggctggttt tatagttaaa agataaccgt taactcgcca aagttaagga
    18901 cggttatttt ttattgtcat ctttgaagat ttgatagcac aagctgataa gcgcaatagt
    18961 aaagctacta aagcctaaaa ggatttatac cacttcaaaa gctgtcaatg ctttgactca
    19021 tcctttctgt tagattttga tgaactgccc ataggcctca cctacctttc agaaataaga
    19081 gccaccgtct taacctttct gctttatcat tatagcatat tgttattaag gttgactatt
    19141 cagactcgtc taaagaagtg taatagttgc ttaattttgg gataagggtt ataatgaaaa
    19201 tagaaaaagg tagttgctcg acacaactac ccatgcagaa ccgtttaaga cggtggcatg
    19261 ttttatgtta ttaaaaaata accgttaact cgccaaagtt aaagacggtt attttttatt
    19321 gtcatctttg aagatttgat agcacaagct gataagcgca atagtaaagc tactaaagcc
    19381 taaaaggatt tgtaccactt caaaagctgt caatgctttg gctcctcctt tctgttagat
    19441 tgtgatgaac tgcccatagg cctcacctac ctttcagaaa taagagccac cgtcttaact
    19501 tttctgcctt tttattatag cataccctat ctctgattga ctagcttaag aaggagggga
    19561 tgtgatttgg atacaaattt ttgttaactt ttttaaagtc tccaaatgat ttaaaaaaat
    19621 gatattaatg ctctaagtaa gaatattaat aatatggttt taccacttat tgtatgaggt
    19681 atcatttcta aagagttatt tttcagacag aaggcttgtt aaagcaaaca gaagcaatac
    19741 taaaggcatt agatgataat caaggccttt ttcatgtctt aaaatgagta tactagctgt
    19801 cgtgttggat agaattcata taatgattta actgcttttg attttttaaa acgattgttt
    19861 tatgaggata ttgtttaata actgctttat agttatttaa attatttttt gagcgtccgt
    19921 ctaacagaat ccatttcata aattcaacat caaatttttc attacagttt tcagccatat
    19981 caggacgtgt ttgtccccta tattttaaat atcgcttaaa agctcggtaa aaacaattaa
    20041 atctattaaa gttaaaatat ataatgtgat cagcctctct catacgctct tcataaagac
    20101 agcttgaata attaccttca ataatccaat gtttttgtga cataaatgtt gatatatcag
    20161 agaccatttg actaactgtt cgctcttgcc agtttgatgc aaaatgaatt ttgtctaaat
    20221 gaagtacagc acaattgtag tgttgaccta aaacatttgc taaagtcgac tttccagaac
    20281 cactatagcc aattattaca attttcaatc tttgtctcct ttgtcaatgc tgtactttga
    20341 cttatattat agcataaaga atatattttg gggacaaatc ctctttagac aagcaaaaaa
    20401 gcctt
//
LOCUS       DARYUW010000037        18397 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYUW010000037 DARYUW010000000
VERSION     DARYUW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18397
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            174..554
                     /locus_tag="TVW11_001300"
     CDS             174..554
                     /locus_tag="TVW11_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1365398.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            554..1402
                     /locus_tag="TVW11_001301"
     CDS             554..1402
                     /locus_tag="TVW11_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1365399.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1502..2713
                     /locus_tag="TVW11_001302"
     CDS             1502..2713
                     /locus_tag="TVW11_001302"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1365400.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2706..4573
                     /locus_tag="TVW11_001303"
                     /pseudo
     CDS             2706..4573
                     /locus_tag="TVW11_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4678..6423
                     /locus_tag="TVW11_001304"
     CDS             4678..6423
                     /locus_tag="TVW11_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365401.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6423..8199
                     /locus_tag="TVW11_001305"
                     /pseudo
     CDS             6423..8199
                     /locus_tag="TVW11_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8340..9689
                     /gene="gdhA"
                     /locus_tag="TVW11_001306"
     CDS             8340..9689
                     /gene="gdhA"
                     /locus_tag="TVW11_001306"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1365402.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9821..10231
                     /locus_tag="TVW11_001307"
     CDS             9821..10231
                     /locus_tag="TVW11_001307"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1365403.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10422..12428)
                     /locus_tag="TVW11_001308"
     CDS             complement(10422..12428)
                     /locus_tag="TVW11_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1365404.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12877..14598
                     /locus_tag="TVW11_001309"
     CDS             12877..14598
                     /locus_tag="TVW11_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365405.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14600..15763
                     /locus_tag="TVW11_001310"
                     /pseudo
     CDS             14600..15763
                     /locus_tag="TVW11_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15915..16691
                     /locus_tag="TVW11_001311"
     CDS             15915..16691
                     /locus_tag="TVW11_001311"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1365406.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            16684..17649
                     /locus_tag="TVW11_001312"
     CDS             16684..17649
                     /locus_tag="TVW11_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1365407.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            17745..>18397
                     /locus_tag="TVW11_001313"
     CDS             17745..>18397
                     /locus_tag="TVW11_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL1365408.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEAT
                     "
BASE COUNT         5472 a         3258 c         4300 g         5367 t
ORIGIN      
        1 cttggggtgt ttttttgttg taggagattg attggttgat agaaggcagg tttatattta
       61 ttgaagtgac aaggtctgga aaaaaattat ccaaaatact ggtttaagtc tactttaata
      121 ttcgtcaaat ctatgctata atgggtcata tcgccattaa ggagaacgaa atcatgcaat
      181 tagtacgtga aaaagaattt gtcaatcagt accattatga cgccagaaat ttagaatggg
      241 aaaaagaaaa tggaacaccg gaaacaaact ttgaagtaac ctttcagttg attaataaag
      301 atgtggaaaa taaagagacg gctattgttt ctgttttaca atttgtcatt gtcaaggaag
      361 agtttgtgat tagtggtgtg atttcacaga tggttcgtat tttaggacgc ttggtggata
      421 agcctagtga atttacacaa gaggaggtcg aatccttggc tgctccatta ttagacatgg
      481 tgaagcgctt gacctacgaa gtgacagaaa ttgccttgga tcgtcctggt attaatttgg
      541 agtttaaaag ttaatgaagt tagcaataat aactgataat acagctcacc ttccagagca
      601 gttagcggag catgccgata tttttgtatt agacatacct gtaatcatag atggtcaaag
      661 ctatgtcgaa ggacaaaacc tgaccattga agccttttac caaagcatga gagaatctca
      721 agagctgcca aaaaccagtc agcccagcct ctctgaatta gatgatttac tagggcgtct
      781 gtcaactgag cactatactc atgtgattgg cttgttcttg gctagtggta tttcaggatt
      841 ttggcaaaat attcaatttc tcatcgagga gcaccctgag ttgaccattg cttttccaga
      901 tagtaaaatc acctcagcac cattaggcag catggttaga aatgctttag agtggtctca
      961 gcaaggcttg agctttgcag agattatgga taagctagaa gagcaaatcg ctggaaccac
     1021 agcctttatc atggttgatg atttgaatca tttggtcaag ggaggacgct tatcaaacgg
     1081 ttctgctttg ctgggaaatt tgctcagcat caagccaatt cttcgctttg atagtgaagg
     1141 aaagattgtc gtctatgaaa aggttagaac ggaaaaaaag gccatgaagc gcttggttga
     1201 tatcttaaag gaattgacag ctagtggtca gtacgaggta tcaattatcc atgctagagc
     1261 gcaggataag gctgatatct taaagcagct cttgttggat aatggctata cctgccctgt
     1321 tgaggaggtt cattttggtg cagtgattgc agcccatctt ggagaaggag ctgttgcctt
     1381 tggcataacg cctcttgtct aaagaggctt gcccatgacc aatctgagct tgatatgaca
     1441 gcctttaacg ggaagcatat gacaaggctc taggagcttt taggtggtag attaaaacat
     1501 gataacatta atgacaatgc cttctgaatt tcagaaggct ttaccaatag tgaaaaaaat
     1561 caagcaggct ggctttgagg cctattttgt tggtggaagt gtgagggata gcttattaaa
     1621 caggcctatt catgatgttg atatagctgc tagctgctat ccagaggaga caaaggctat
     1681 tttcttaaga acaattgatg ttgggattga gcatggcaca gtgcttgttt tagaaaatgg
     1741 cagtgaatat gagatcacaa cgtttcgaac tgaggacgtt tatgtggatt ataggcgccc
     1801 tagtcaggta tcctttgttc ggtccttgga agaggattta aaacgaaggg attttactgt
     1861 caatgctctt gccttagatg aggacggaca ggttattgat atctttaatg gcttagagga
     1921 cctaaagcat aagcttctaa gagctgttgg aaggcctcag gagcgctttg aggaggatgc
     1981 cctgcggatt atgcgaggct ttcggtttgc tgccagctta gattttgata ttgaggctga
     2041 gacctttgaa gcaatgaaaa gccatgctcc cttgctggag aagatttcta ttgagcgctc
     2101 ttttattgag cttgataagc ttttaatggc cccaaaatgg cgtaaaggta tcttagctat
     2161 ggtggcatgt caggccttta actatttgcc aggcttagtg ggcaaggaag aagccctgca
     2221 aaagtacctg aaaaccttag cagcggatta tgtgtttcag gacaatcatc aggcttgggc
     2281 ctatttgctg gttatgctgg agcttgatca gcctaaagcc tttttaaagg cttggaaaac
     2341 ctctaatgat tttcagcgta gggttacgat gatggcctct ctttatcaga ttcgccaaga
     2401 aagacagcta gaaaaatggg atatttactc gtttggcaag gacttggctt tactcgttga
     2461 cgatttacga caggcacagg gcttggtcag tgaggccaag cgtgttgaga gcttgtatca
     2521 ggagctgacg atccatgata agcatgatat tgtggtcaat ggctcttatc tgattcgtga
     2581 gcttggaatg aagccaggac cacagctggg aatgctttta aatcagattg agcaggccat
     2641 tgtagagggg cgtctcgtca atcaaagaga acacattgag gcttttgtta gaagggaact
     2701 actaaatgag tgattttatc gttgaacatc tgacgaagtc tgttggagat aagaccgttt
     2761 ttcaggatat ttcctttatt attcatgctg gtgatcgcat tggcattatt ggtgtcaatg
     2821 ggacaggaaa aacaaccttg cttgatgtta tttctgaaaa agtgggcttt gatggtgacc
     2881 gctcaccttt ttcaaaggca aatgactatc gtatatctta tttaacacag gagccggact
     2941 ttgatgatga tcagtctgtt ttagatactg ttctgtccct agaattaaag gaaatgcagc
     3001 tgattcgcca atatgagctg ttgatggctg actattcaga tagcaatcag gaaaagctag
     3061 cagaggtgat gactgagatg gatcgattag atgtttggtc gatcgaaagt gaggttaaga
     3121 cggtcttatc aaagcttggt attgtcaatc tggatcagag agtgggtgac ctgtccggtg
     3181 gtatgagacg tcgggtacag ctggctcagg tcttgcttgg agccagtgat ttgttgctgc
     3241 tagatgagcc gaccaatcat ttggatattg ataccatcgc ttggttaagt cattacttaa
     3301 ggacctctaa aaggactgtt ctatttatta cacatgatcg ctattttttg gatagtatag
     3361 ccacacgtat ctttgaattg gataaggctc atgtgactga atatcagggc aattaccagg
     3421 attatgtgcg tctgaaggct gagcaagacg agcgcgaagc agctcatttg cataagaaaa
     3481 agcagctcta taaacaggag ctggcttgga tgaggacaca gccacaggcg cgtgcgacca
     3541 agcagcaggc cagaattaac cgctttgaac agttaaaaaa ggaccttcat caggaaaggc
     3601 ctatagatca attagatatg gcctttgaag ccagtcgtat tggcaagaag gtcattaatt
     3661 tcaaggaggt ttcctttgct tatggtgatc aggccattat tgagcatttt aacctgatca
     3721 ttcaaaataa ggaccgtatc ggcattgttg gagctaacgg tgctggaaag accaccctgc
     3781 ttagcttgat gactggtgac ttaaaaccaa cagctggtca gctagagatt ggcgagacga
     3841 tccgtattgg ttatttttca cagcaaatca aggatatgga cggcagcaag cgcgtgatta
     3901 gctatttgca ggaggtggca gatgaggtca agaccagtgt tggcaccact agcatcagtg
     3961 agcttttgga gcaatttctt tttccgcgtt ctagtcatgg ctccttaatc gctaagctat
     4021 caggcgggga gaaaaaagac tgtatttgct aaagctcttg atcgaaaagc ccaacgtcct
     4081 gctgctggat gagccgacca atgatttgga tattgcaacc ttgacagtgt tggagcattt
     4141 tttagctcaa tttgctggtc cggtcattac agtgagtcat gatcggtatt tcttggataa
     4201 ggttgcaaca aaagtattgg cttttgagca tggagctatc agagaatact atggtaacta
     4261 tagcgactat ttagatgaaa aggcttttga agcagaggtc atagagcctg ctgtcagtga
     4321 gcaaaaagct ggcactgacc atcaggtcac ctctaaaaag agaatgtcct atcttgagaa
     4381 aaaggaatgg gcagctattg aagaaaagct agctgctatc gagcaacaaa tagctactat
     4441 tgaggagcaa atgctcagag cggcaagtga ttacgaccaa ttggcacaat atcaaaagga
     4501 gctggatcag cggaatcttg agctgcttga agcctatgag cgctttgatt acctaagcga
     4561 attagaagaa taattaatta tgtgtcaatt tcatattttt gtgttaaact agttatagac
     4621 aaaaagaagt gctagcttgc gcttcttttc atatcactat tatttgggag gaaatgaatg
     4681 gctttaattt ggtcctattt aaaaacaaga cctaaatgga tttgtttcga tattgtgggt
     4741 ggcttgttat ttgttctggt caatctgggg ctaccaacaa tattggctcg tatgattgat
     4801 caaggcgtta tgcagcagga tcaaagggct ctttattttt gggctctgat gatgtttatt
     4861 atcgtacttt taggtgtcat tggacgggtg attttatcct atgcttcggg taagctaacc
     4921 accaacatga tcaaggattt acgtaatgac atgtatagct gcttgcagga ttattcgcat
     4981 tcggaatatg aaaaaattgg catagcctcc ctggttactc ggataacaaa tgatgccttt
     5041 gttttgatgc aatttgctga aatgtccttg aggctgggtg tcgtaactcc tttgatgatg
     5101 atcttttcag tggtgatgat ctttttaacc agtccatcat tggcttggat tgtggctgtt
     5161 gccatgcctt ttttagttat tgtggtgctt tatgttgcga taaagacaag acccttatca
     5221 gaaaagcagc aggagagcct tgatcgtatt aaccaattgg tgcgtgaaaa cctgacaggt
     5281 ctgagagtta ttcgagcctt tgcaagagaa gactttcaag aagagcgctt caataagcgc
     5341 aatgatcact attctggaat ctcaaagcga ctatttacct tgacaggctt aacagagccc
     5401 ttatttgtgc aaattatcat tgctatgatt gtggggatcg tctggtttgc cttggatccc
     5461 ttggcaaggg ggcagtttaa gattggtgat ttggtggcct ttatcgaata tagctttcat
     5521 gctctttttt catttttaat gtttgccaac ctctttacca tgtaccctaa aacagcagtg
     5581 tcaagcaagc gtatcaagga agtgctggat atgccgattt cgatttctaa aaatgaagat
     5641 ggtataacag cgttcacaac acgtggttat ctagaatttg ataacgtgac ctttgcctat
     5701 ccgggtgaaa cggaaagtcc agttttacat aacatctcat ttaagactag gcctggagag
     5761 accattgctt ttatcggctc gacaggttca ggaaaatcat ctttggttaa tctgatccca
     5821 cgattttatg acgtgacctt agggagaatc ttggttgatg gcattgatgt cagggattat
     5881 caattaaaag cgctgcgttc taaaatcggc tttattcctc aaaaagccct gctatttaca
     5941 ggaaccattg aggaaaacct aaaatatggt aagtcagatg ccagccacag tgagcttgag
     6001 caggcaacag aggtttccca agcgaaggac tttattacca gtcgtgaaaa gggctatcaa
     6061 acccatctag ctgaggccgg cagtaatcta tcaggagggc aaaagcagcg cctgtctatt
     6121 gccagagcag tggtcaagca gccagacatc tatatctttg acgattcctt ttctgcccta
     6181 gattacaaga cagatgctga attacgcaga cggctgaaag aggtgacaca agatgcaacg
     6241 gtcttaattg tggctcaaag ggtgggcacg attatggatg ctgatcaaat cattgtcttg
     6301 gatcagggag aaattgttgg ccgaggtaca catgaggaat tgcttacaag caatgccatc
     6361 tatcgtgaaa ttgccaattc tcagctaaac aaggaagaca tgacaaaaga ggagggggat
     6421 taatgactga aaagcatgtg tttagaagaa tttggaccta ccttagtgcc tataggctct
     6481 cactaataac tgccattatt ttaaaaatag tcagtgctgt gatgagtgtc ttagagccct
     6541 ttgttcttgg cttggtgata acagagctat ctgcaaacct attagacata gcaaagggag
     6601 tctctggtgc aggcattaat aaaacctata tcgcctttct tttagctctc tatatcatta
     6661 gggcccttgt ttacgagtta ggctcttatg gttcaaacta ttttatgaca agggctgtgc
     6721 aatcaagcat ttgtgatctt cgtcgagacc tcagtcaaaa aattaatcgt atccctgtgt
     6781 cttattttga taagcatcag ttcggcgata tgctaggccg gtttacctct gatgttgaga
     6841 cagtctctaa tgccttacag cagtcctttt tacagattgt taacgccttt tttaccctta
     6901 ttttggtggt tggcatggtc ttgtatatta atgcccccct agcctctgtt gtgattatcg
     6961 ctatcccgtt gatatatgct gcttctcgat ttgttttaaa aaaatcacag ccttatttta
     7021 aagcgcaggc taatattttg ggagaaatga atggctttgt gcaggaaaat ttgaccggct
     7081 ttaatatttt aaaactgtat ggtcgtgaag aagcctcaaa ggaggaattt caccagatca
     7141 ctgagcgatt acaagaagta ggctttaagg ccagctttat ttctgggatc atgatgccag
     7201 ttctgcattt tatttcagat tctgtttaca tgattgttgc cttaatcgct ggcttacagg
     7261 tgatagcagg ccgcctgaca atcgggaaca aacatgcaag cctttgttca gtacatttgg
     7321 caaatcagtc agcctattca gaccataaca cagctggctg gtccactgca aagtgccaag
     7381 tcatccttag aacgtatctt tgcagtgctt gatgaggcag atgaattgac tattgcccaa
     7441 gagcatttag aacatgattt aacaggtcag gtgtccttta atcaggttga ttttagctat
     7501 acagcagaca atcctctgat tagaaatttc aatttagagg ttaagcctgg tgagatggta
     7561 gctatcgttg gtccgacagg agccggcaag accaccctga ttaatttatt aatgcggttt
     7621 tatgatgtga atgagggctc tatcacagtt gatggtcagg acattcgtca gttgtcacgt
     7681 caagcctata ggcgtcagtt tggtatggtg ctgcaggacg cttggctctt tgagggcagc
     7741 attcaggaaa acttgcgctt tggtcattta gaggcgactg atgaacaaat aattgaggct
     7801 gctaaggctg ccaatgttga tcatttcatt aggacattgc caggtggcta tcatatggtg
     7861 atgaatcagg aatctagcaa tatttccctg gggcaaaagc agctgctgac cattgctcga
     7921 gctctcttag cagatccaaa gctgctaatc ctagatgagg ccacctcgtc tgttgataca
     7981 cgtttagagc ttttgattca aaaggcgatg aagcgattaa tggttggcag gactagcttt
     8041 gttattgctc accgcttatc aaccattcaa gaggcggata agattttagt tctaaaagat
     8101 ggtcagatta tcgagcaggg gaatcatgac agcctattag ctgctaaggg cttctattat
     8161 gagctttatc atagccaatt taagaccagt cagtcttaaa aagcttaggg tcttggaatg
     8221 aatcgttcca aggctctttt aatttgcttt agatcatagt aaaagcttga catcaaaatt
     8281 cagaaaattt ataatattga ctatacttaa aatagaatga agaagcgaga ggatatataa
     8341 tggtatcagc aaaagactat gtagccagtg tttttgataa ggtcaaaagg gataatccgc
     8401 atgagactga atttcttcag gcggtcaagg aggtatttga ttccttgatt cctgtttttg
     8461 aaaaataccc taattatatt gaggaaaatc tattagagcg cttggttgag cctgagcgtg
     8521 tgatttcctt tagggtgcct tgggttgatg accagggcag ggtccaagtt aatcgtggct
     8581 accgcgtgca attttcatca gctatcggtc catataaggg agggcttcgc tttcaccctt
     8641 ctgttaacca gtctatagtt aaatttcttg gctttgagca gattttcaaa aatgctctga
     8701 ctggtcagcc tattggagga ggaaaaggag gatcaaattt tgatcctaaa ggcaaatcag
     8761 acctagaaat catgcgcttc acacaaagct ttatgacaga gctgcaaagg catattggac
     8821 ctgaccttga tgttcctgct ggtgatattg gtgtaggggc tcgcgaaatt ggctatttat
     8881 ttgggcaata taagcgtctt aatggcttta agaatggtgt gttgacagga aaaggcttag
     8941 cttatggtgg ctctttggct cgcacagagg ccacaggcta tggtgtggtt tattttgctc
     9001 agcaaatgct ggcggctaag gggcaggact tggctggtaa aacagctatt gtatctggat
     9061 caggaaatgt tgccatttac gcaacggaaa aattgcaggc cttaggtgtt aaggtattag
     9121 cagtgtcgga ttcctctggt tacgtttatg atgataaggg cattgatctt gagaccctaa
     9181 agcaaatcaa ggaagtgaag cgtgagcgta tcaagaccta tctagagagt cacccggctg
     9241 ctgtgtttac accggctggt gagggatcca tctggactat taaggcagac cttgcctttc
     9301 catgtgcgac tcaaaatgag ctacaagagg cagatgctaa agccttgatt gagcatgggg
     9361 ttaaagctgt tgtcgaaggg gctaacatgc cctcaacctt agaggctatt gagcaatttc
     9421 agcaggctgg ggttcttttt ggacctgcta aagcagcaaa tgctggcggt gtagcagttt
     9481 ctgcgctgga aatggcacaa aatagcggac gtaccgcatg gacctttgaa gaggtggatc
     9541 atcgattgta tgacatcatg aaggctattt atcaaaaagc agccgctgcc gccaaggaat
     9601 gtggtcaaga aggcaaccta gtggtgggag ctaatattgc aggctttctc aaagttgctc
     9661 aggccatgtc agcacaggga atcgtttaag agctgtggct ggtatatgct gaatatatca
     9721 gtagggttag cacattaatc ttagctcaat gacgttaaga tatacgatcg gtcatctaga
     9781 caatgcatgc cgattagagc aatgaatcaa ggagaagctg atgatcaaaa aaatcgtgaa
     9841 ggacaccttt ttcttgcagc aaaaagcaca gccagcaacg aaaaaggacc tttggattgg
     9901 tcaagacctg caggatacct tagcttatta tcgtgatagc tgcctggggc tggctgctaa
     9961 tatgataggg gaaaacaaga gggttattat tattagcatg ggctttgtgg atttggtgat
    10021 gtttaatcct gtattaattg ctaagcgtga agcgtttgag gcagaggaat cctgcctatc
    10081 actaatcggc caacgtaaga caaagcgtta tcaggagatc aaggttgatt accttgatgc
    10141 acattggcac aagaaatccc tgagattgac aggcctgcct gcacaaatct gccagcatga
    10201 gctggatcat ctggagggca tattgattta aatcatgacc acccgttagt gaactgcacc
    10261 ccaaaagtta gacagaaaat ctaacgaatg agggcagtcc atagatgggt ggtttatttg
    10321 tcttgctcaa caggtgcgaa acaaataaac gtcacataaa tcagaaaacc ggctgtatgc
    10381 ttaagataca gtcggttatt gctgttatgg ctaggacgat tttattggcc ttcctttttc
    10441 ttgaaaaggc tagtaccagt taaggttagt agtcctagga ttgtcatggc agcagcagaa
    10501 tgctggcttg ttcctgttgc tggtaaggca gcattagctt gctttttagc tgctagaggc
    10561 ttgatgcttg tggcaggatt agcattttga gcaggcgtaa ataggtcaga gacaagctca
    10621 gtagcaagca ccttgccctc acgattctta aagacgcggt tgatgatctc gtgcttgccg
    10681 gtatgatcac tttgagtaga gccttcaaga ctggcagtga cataggtttt cacaccgtta
    10741 ataccagcac ttacagtctt tccagctgct tcaaggtcct tgatgtattc gataaagacc
    10801 tcagtatcag gattaatggc tcctagtagc ttagcgtcct taaagacgga gaagccatca
    10861 ccaccgccat ataggaagtc gttgatgatt agggtgtatt gagctgctgg atcaatttct
    10921 tcaccattat ctttataagc ctttactacc ttaaacggtg ttgaaggatc gttagcctca
    10981 ttagctgtat aagtgtattt gagtccagac atttgaagga agtatttttg gtcttcatcg
    11041 tattgttggt tcaagacatc atagatttgt tggccagtca tttgaacgac ctgaagaata
    11101 ttgccaaatg gttgaacagc ctgtgcagct ccccaggtaa tggtttgatc ctctttgacc
    11161 accaagtcag cgcgaatacc gccattattt gtcatggcaa aatcaacatg agggaaggtt
    11221 tttctaccaa tggttaattg ggcagttgtt atcaaattgc caacaggaga ttccttgtct
    11281 tcgttttctg ttttagaaat cgttgaagag gtagctgctg taccgatctt tagctcggta
    11341 acggttttga caatgtcatt ggcttgatca acaatggctt gaatgtcggc attgcctgtt
    11401 tttatgccag gagcaacggc aatgaccttt gcttcaggag tggctacaaa atcattgagg
    11461 tcagtgtcta gtgttccacg aacatctgca taggctttcc cctgtgaaac agcctgaacg
    11521 acacgtgttg tgccaatggt accgttggtg tattggtggt tgtgaccagc aaagacaata
    11581 tccacactat gctcaggata aagctggtta accttttcca taactgctgc catctcatca
    11641 tgaactaccc cgttatcact tgttgctggg atatgagcta ggacaacaat cgcattgacc
    11701 tgctgctctt ggagctcttt agcatattta acgatggttt ctgcagagtc taggtaatca
    11761 tattgttcat aattttgttt taggacaagg tttggaattt ctgttgtcac aacaccgata
    11821 aagcccacct tgactgactt atcattaact gggacttctt tgacagcata aggcttccag
    11881 ccaaaaggaa tcgtgttggt ctccttgtca acgacatttg caatgacaag ggtttgattt
    11941 gaagcttcat gctcgtattg cttagtaatg tcgttgatag ctgagtcttc agcaggtgca
    12001 gtgcctgtca tgatacggtt gaattcagct aagccctcat cgaattcgtg attcccaagg
    12061 gttccgtatt caaagcccat ctggttgaat accttaaccg ttggctcgtc ctgtaatagt
    12121 ccagaattag caggactagc tccgaccata tctcctggtt gaacacgaat gcttgtccca
    12181 tctgggcttg tttgcttaaa gtcagcctct gcatcgtcca gataagcagc taattgtgct
    12241 gcggtaccag cgttagatac ctttccttct ggcatgtagg cagagccggt tgtgtctaag
    12301 gcaccatgaa agtcattgac accaagaaat tgcacgtcta cctgatcggc ctgcacgccg
    12361 gttactagca tagaaactcc ggcaaagaca ccaagaacac tactttttaa aacaaaatgc
    12421 tttttcataa acgctcctaa aagtttaaag tattgtcaca agttaagtgt actattattt
    12481 aaatgagaat tcaacaaaaa ttaataaaaa agctaacaaa aattcaacga tagcgtttgc
    12541 taatcactga aaacgtttaa aatgcaaaca ttggaagcgt tttttgtaaa aaaatagaag
    12601 aactatccaa aaaaggcttt acaagcccag tattctatga taagatgtta ggcagattaa
    12661 aagaaaggag aaattaataa tgatccgttt cattcaacta tttaaccatt attacgatag
    12721 tctcctttct aaccaaaaca gttagtttct tttagtttca ctaaatagaa atagtagagc
    12781 ccgcggtagg aaggatatct tattgcgggc tttttgtgtg caaaaatcct attttaagac
    12841 agcttgaaat aggttagttc agaaatggag gatatgatgc tgaccttaat tgttcaacat
    12901 attaagcaaa agaaatggat ttatatcctt attgcaatga ctttagtgat atatgatgcc
    12961 tcacttgtga taccaacaag ggttattcaa gacttggttg atttgatgtc aaggcatcag
    13021 ctaagctcag gggcattggt gaggcatgtt atcattcttt tggctacggc agtagtgtct
    13081 tatggggttg cttatttgtg gcatcttcat ttatttcagg aggcagttca ttttaagttt
    13141 gatattcagc agcgtgcctt tcgaaagctt gtttttatga gaacgccttt ttatgagaaa
    13201 tttcgctcag gtgacatgat cacgcgtttt tcaacagatg tcgaagcact tatggacctt
    13261 atcggctatg gcttgatgat tatcctatat gctggtggta tgattgcttt tattattccg
    13321 accatgtttt tgatttcttg gaaaatgacc ttgataggaa tagtaccgat tttgcttatg
    13381 atggtgatga tctatggtgt gacgaaaaag caagagcatt tggttgaaga ggcgcgtgag
    13441 gcgatttcaa gccttagtga tgaggtacta gaaaccgttg agggcattag agtgatgcgt
    13501 gcttacagta aaaaagatta tttggcactt cattttgctc aaaagactca gaatttggca
    13561 gataaatgga atcaggtggc caagtatcgt gccttgtact ttcctcttta cagcgtcatg
    13621 attgccatta gtacagtaat cattttaatg gtaggcctac agctcatagc aagctcagag
    13681 gtaacacttg gtcaagtcat tgcgctgcag ctttatctgg tgtctttggt ggagcccttt
    13741 ggcatgctgt cagactttat tttggtttat cagacaggaa agacctcttt tggtaagatt
    13801 aatgaactca tcgaaacaag tgatgatatg gagcctgatg gccagcttga gttagagagc
    13861 tttgatcaga ttgcttttat agactatagc tttacctatg ccaatagttc taggcctagc
    13921 ttagaaaaga tcaatttaac cctgaaaaag ggacaaacct tagggattgt tggtaaaaca
    13981 ggctctggta aaacaaccct tgtcaggcag tttttgagac aataccctct tgggcagggg
    14041 cagctgatga ttaatcatcg tagtgtcttg gattataagc gtcaatcact tgagcgtcaa
    14101 attggctatg tgccacagga gcatatcctg ttttcaaaaa cggttgctca aaacattgcg
    14161 atggggaaaa aggcagctac aactgaggaa atcttggagg cgattgaaac tgcggccttt
    14221 acgcgtgatg ttcaaggaat ggcaaagggc ttggatactg agattggaga gcgtggtctg
    14281 tctatttcag gaggtcaaaa gcagcgtatt tcgattgcca gagccttttt gtcccagcca
    14341 gatttgctga ttttagatga ttccctgtcg gcagttgatg ctagaacaga gactgatatt
    14401 attcgacaca ttcaagacga aagaaaggga aagacaacac ttattgttag ccatcgcttg
    14461 tctgcgattc agcatgccga ttgggttatt gttctggatc aggggcagat agtagaggaa
    14521 ggtcagcccc aacaactttt agctcagaag ggctggtatt atgaacagta ccagcgtcag
    14581 caggctcagg aggtttaaga tgaccctatt tataaaatta ataaaagaaa ttaaagctgt
    14641 gaccttggct ttttccctgg caataggctt tttgctagtg gcaacagctg gaggtcagat
    14701 ggctccctta ttgttgcaac aaacgattga tcattacttg actccgatag ctagaggaaa
    14761 agaggtaccg attgaaggct ttcagcgctt gctcctgctg tatttgctgt taattgtgat
    14821 aacagcagtt ttgcgttata tctcttatcg aatgctggtt tattcctcta ataggatcgt
    14881 tgctaatctt cgtaatcgag cctttgatgt catgcagagg ctgccgatag cttattttga
    14941 tcatcagcct gcaggaaaga ttgcaactag gattgttaat gatactgaaa ccctgaagaa
    15001 tcaattttat gataaccttt tgtctcaaat tattgtcagt ctttcacaaa ttatttttat
    15061 ttatgtggtg atgatttacc ttgatgtgaa gtcaggcttg ctgttgctgc ttattatgcc
    15121 actcttttat ggcatgcaat ggctgtataa aagcttgact gaccagccaa tgaaggattt
    15181 ttatcaggct aggagcgctg tcaacacaca agtcaacgaa accatgaatg gtgtttctat
    15241 tattcagctt tatcatcaag aggatacgat cttagaggaa tttgaagagc agatccacca
    15301 gatgaaaaca gctgatgata ggattatttt tgcagagtca gttgcttcat ggaccctgac
    15361 ggaattggta aagtatggca tgattgccgc tattttggct gttattggtt accagttctt
    15421 gcaggggaga tcaggcatca cagttggtaa gctctttatt tacgtcaatt atttgctgcg
    15481 cttgtttgat ttattaagta tgctggttag gcagctacct aatattcagc gctcaacagc
    15541 gacaggaacg cgcctaatga agctgcttga ggcgcagaca gagccggata aagcacgagc
    15601 aattgagcta acagatggta ctgtggattt taccaaggtg tattttgctt acgaaaatgg
    15661 caagacagtt ttatctgata ttaccattca tgctgataaa ggggagacgg ttgccctagt
    15721 agggcatact ggctctgggg acaatgctat aatgatgata gtacaataaa tccaagtaaa
    15781 atcaatggtt aaaggcttcc gcaaaacttt taaacttgat gatggattga ggctatcatc
    15841 tttttttata tctaaaatta tataaaagta tagcataaaa tgaaatctct gtatagagaa
    15901 gaaggaggga ctttatggca gaagtgataa ccatagccaa tcgaaaaggc ggagttggaa
    15961 aaacaactac aactctaaac cttgcctatt cactaaaaga actggggaaa aaagtattag
    16021 tcattgacct tgatccacaa gctaatctta caagatgttt tgatatggga aatacagaaa
    16081 atataaaaac catagggcat ttgttaatgg tagaactgga ggaagaagaa agctatttgg
    16141 tagagggcta taccaaatct tatgatgaga tagatattat cccctcaagc attttcttat
    16201 ccgccgttga aacacaaatg agagcagaaa caggaagtga acgtatatta tcggaaatta
    16261 ttaggagggt aaaagagaat tatgactata ttctcataga tacatcacca tcacttagtg
    16321 ttttgactat aaatgctctt tgtgcctcag acagtgtcct tatagtagcg gatacacagc
    16381 tgttcgcagt tgttggaatc aatgaacttt taaaaactgt tcaaaaaata aaaaagagag
    16441 tgaatccgaa actgaaagtg caggggattt tactaaccat gtgtgagaat agaaccaatc
    16501 tgtccaaaac actgatggag caagtagaag aaatgttcca aaagaaaatc aaggtctttc
    16561 aaaccaaaat tccgaaaaca gttaaagttg gggaagccat ctatagcggg caaagcataa
    16621 aaaaatatgc aaaaggcagt agtgtagaca ttgcctatga caatctggca aaggagatct
    16681 gctatgagta aaaaacttct aaagagagaa atcaccgatg ccgtagattt tttgcttgat
    16741 gatggaaatg ccttggaaca aggaaatata cagaatatag aacttgattt gcttgaaaat
    16801 tatcataatc atccgtttac tttatataca ggtaagagat tagacgatat ggtagagagc
    16861 attaaggaaa acggagttct taatccaatt atcgtcttga aaaaagataa caactatgaa
    16921 atactttccg gacacaatag agtaaatgca gcaagaatta caaaaataaa aagtattcct
    16981 tgtattgtta aagaaaatct aacggataaa gaagcctata cctatgtaat tgaaacaaac
    17041 cttatacagc gttctttctc cgatttactg ccgacggaaa aagcccttgt tcttaaaatg
    17101 agatatgaaa aaatagcaag tcagggcaag agaaatgatt tgcaaaagga gataaacaat
    17161 ttagatcagg gaattataga aaaggaaagt aaagaggaag ataaaataga cagcagaaaa
    17221 acacttggaa aagaatataa tctttcaggg gcatctattg caaggtacct aagattaaat
    17281 gaattatcta agtcttggaa aaaagatgtg gatgaagata aaataggttt gacgatggca
    17341 gtagatttat cctatctttc caaagaaata caggaatatc tgtatcagaa gtgcgaagaa
    17401 ttggaactaa gtttaaaacc aagcgatgcc aaagcactcc atctgatgaa cagacaagaa
    17461 gatctgaatc aagagatggt tataacatac ttgctgaact tgaaaaaaac gaaggtaaaa
    17521 aagtatcaga atatcaaact atctcagagt gtctataaaa agttttttca tgatgaaagg
    17581 aaagaagatg tagaagaaat tatagaaaaa gcattggaaa tttactttaa ggaatatatt
    17641 ggtcagtgaa aagacaaaat tataaattta aggtataata taaggtatta aaaagggaaa
    17701 agacctgttt aacaggataa gatataaaag aggcaggtgt cagaatggac gaaataaaat
    17761 tgtatgaaaa taaagagata cgctccattt gggacgaaga aaaagaagag tggtattttt
    17821 cagtagtcga tgtagttgga gttttgacag aacaagaaaa cgtaagaggt gctagtacct
    17881 attgggctgt actaaaaaag agattaaaag aagaaggaaa tgaactgctt acaatttgta
    17941 agcagttgaa aatgaaagca acagatggaa aaatgcgttt aactgatgta gcagatatgc
    18001 aaggaatatt ccgtattatc cagtccatcc catcccctaa agcagaacct tttaagttat
    18061 ggcttgctga ggttggaaaa gaacgaattg atgaaattat cgatcctgaa cttacgattg
    18121 acagagcctt agaaacttat ctaaagaagg gatatacacg tgagtggata aatcaaagac
    18181 ttcaagccat tcaggtaaga aaagaactga ctgatgcttg ggatgaccat gggatacaaa
    18241 aaggcaaaga atacgcaatt cttactgatg aaatcaccaa agcatggtcc ggaatgacaa
    18301 caagaggtta taaaaatctg aagggtttga aaaaggaaaa tctaagggat aatatgacca
    18361 ctcttgaaat agttcttaat atgcttgcag aagccac
//
LOCUS       DARYUW010000038        18226 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYUW010000038 DARYUW010000000
VERSION     DARYUW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18226
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            310..2454
                     /gene="pnp"
                     /locus_tag="TVW11_001314"
     CDS             310..2454
                     /gene="pnp"
                     /locus_tag="TVW11_001314"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1365409.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2447..3199
                     /locus_tag="TVW11_001315"
     CDS             2447..3199
                     /locus_tag="TVW11_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1365410.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3211..3747
                     /gene="cysE"
                     /locus_tag="TVW11_001316"
     CDS             3211..3747
                     /gene="cysE"
                     /locus_tag="TVW11_001316"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1365411.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3865..5208
                     /locus_tag="TVW11_001317"
     CDS             3865..5208
                     /locus_tag="TVW11_001317"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1365412.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5201..5608
                     /locus_tag="TVW11_001318"
     CDS             5201..5608
                     /locus_tag="TVW11_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1365413.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5825..6613
                     /locus_tag="TVW11_001319"
     CDS             5825..6613
                     /locus_tag="TVW11_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365414.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6662..7408
                     /gene="rlmB"
                     /locus_tag="TVW11_001320"
     CDS             6662..7408
                     /gene="rlmB"
                     /locus_tag="TVW11_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1365415.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7409..7927
                     /locus_tag="TVW11_001321"
     CDS             7409..7927
                     /locus_tag="TVW11_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1365416.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8111..8971
                     /locus_tag="TVW11_001322"
     CDS             8111..8971
                     /locus_tag="TVW11_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1365417.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9510..9956
                     /gene="rplM"
                     /locus_tag="TVW11_001323"
     CDS             9510..9956
                     /gene="rplM"
                     /locus_tag="TVW11_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1365418.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9976..10368
                     /gene="rpsI"
                     /locus_tag="TVW11_001324"
     CDS             9976..10368
                     /gene="rpsI"
                     /locus_tag="TVW11_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1365419.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10483..11574)
                     /locus_tag="TVW11_001325"
                     /pseudo
     CDS             complement(10483..11574)
                     /locus_tag="TVW11_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11628..12146)
                     /locus_tag="TVW11_001326"
     CDS             complement(11628..12146)
                     /locus_tag="TVW11_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365420.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12299..12583
                     /locus_tag="TVW11_001327"
     CDS             12299..12583
                     /locus_tag="TVW11_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1365421.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12592..13077
                     /locus_tag="TVW11_001328"
                     /pseudo
     CDS             12592..13077
                     /locus_tag="TVW11_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13129..13416
                     /locus_tag="TVW11_001329"
     CDS             13129..13416
                     /locus_tag="TVW11_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1365422.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13431..13721
                     /locus_tag="TVW11_001330"
     CDS             13431..13721
                     /locus_tag="TVW11_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365423.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13714..14076
                     /locus_tag="TVW11_001331"
     CDS             13714..14076
                     /locus_tag="TVW11_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1365424.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14076..14432
                     /locus_tag="TVW11_001332"
     CDS             14076..14432
                     /locus_tag="TVW11_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1365425.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14776..16320
                     /locus_tag="TVW11_001333"
     CDS             14776..16320
                     /locus_tag="TVW11_001333"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1365426.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16322..17578
                     /locus_tag="TVW11_001334"
     CDS             16322..17578
                     /locus_tag="TVW11_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1365427.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQTRPN"
     gene            17583..18188
                     /locus_tag="TVW11_001335"
     CDS             17583..18188
                     /locus_tag="TVW11_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1365428.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
BASE COUNT         5482 a         3305 c         4175 g         5264 t
ORIGIN      
        1 gcaggtcttt ttttgctgcg tcatcagcgg cttagcgtgc ttggctgtag ggctatagtg
       61 ataaaagaga gtgctgctgg tattgacagc cctttcaaac tttttctagg aatgcctttt
      121 agggtcgtga atttttaact attttatggt aaaatgtagc agatacgtcg tttgatacaa
      181 agaggagtgt gtaattcctt acagattgct ctttgtagca aaacaacgta tagccataaa
      241 aaataaaagg ctagcaagct ttggtcgggt caaacggcta tggtaggcta gctcgttcaa
      301 ggagaaagaa tgtcaaaaca aacatttaca acaacctttg caggcaaacc acttgttgtt
      361 gaggtcggtc aagtagccaa gcgagcaaat ggtgccactg tcgttcgtta tggggagtct
      421 acagtgctaa ctgctgctgt catgtctaag aagatgtcaa caggagactt tttcccgctt
      481 caagtcaatt atgaagaaaa aatgtatgcc gcaggtaaat ttcccggtgg ctggatgaag
      541 cgtgagggac gtccgtcaac agatgcgacc ttaaccgctc gcttgattga ccgccctatc
      601 cgtcctatgt ttgctgaggg ctttcgtaat gaggtccagg tgattaatac tgtcctgtct
      661 tatgacgaag atgctagtgc ccctatggct gctatgcttg gtagctcatt agccctatcg
      721 atttcagata ttccttttaa tgggccgatt gctggtgttc aggtggccta tgttgagggt
      781 gaatttatca tcaatcctga taaggcccag caggaggctt cattattaga gttaaccgta
      841 gcaggaacaa aagatgcgat caatatggtt gaatctggtg ctaaggaatt gccagaggct
      901 attatgctag aagcactttt ggttggccat aaggctatac aggagttgat tgcttttcaa
      961 gaagagattg ttgcagcggt gggcaaggaa aaggctgagg tagagctatt acaggttgct
     1021 gctgatttgc aggctgagat catagagact tacaatgctg atttgcagca ggctattcag
     1081 gttgaggaga aaaaagcacg tgaagccgca accgaggctg tcaaggagcg tgtcatagct
     1141 gcatacgagg agcgttatgc agcagacgaa gagcatgacc gtatcatgcg tgatgtggct
     1201 gaaattttgg agcaaatgga gcatgctgag gttcgtcgcc tcatcactga ggataaggtt
     1261 cgtcctgatg gtcgtcgtgt tgatgagatt cgtccgcttg ctgctgagat tgatttctta
     1321 ccaagggtgc atggctcagg cctctttacg cgcggtcaaa ctcaagcttt gtctgtcttg
     1381 actctagccc caatgggaga tactcaaatt attgatgggc ttgagcctga gtacaaaaaa
     1441 cgcttcttgc accactataa tttccctcaa tattctgttg gtgagacagg ccgctacggt
     1501 gcagcagggc gtcgtgaaat tgggcatggt gctttaggcg agcgcgctct tgcacaagtc
     1561 cttccaagcc ttgaggcatt tccatatgct attcgtctag tggctgaggt attggaatca
     1621 aacggttctt cctcgcaggc ctctatctgt gcagggacgc ttgctttgat ggctggtggt
     1681 gtgccgatca aggcaccggt tgcgggtatt gctatgggac ttatctctga tgggaccaat
     1741 tatactgttt taacagacat tcaggggtta gaggatcatt ttggcgacat ggacttcaag
     1801 gttgctggga cacgccaagg gattacagca ctgcaaatgg atatcaagat cgaaggtatc
     1861 acccctcaaa tcctagaaga agccttggcg caggctaaaa aggctcgctt tgaaattctt
     1921 gacttgattg aggcaaccat tgctgagcct cgtccagaat tggcaccaac agcaccaaag
     1981 attgatacca tcaagattga tgttgataag attaaggtgg ttattggtaa gggtggcgaa
     2041 accattgata agattattgc tgagacaggt gttaagattg acattgatga ggaaggaaat
     2101 gtttcaatct actcaagtga tcaggacgct atcaatcgtg ctaaggaaat cattgctagc
     2161 ctagtacgtg aggctaaggt aggagaggtc taccatgcta aggttgtccg tattgaaaaa
     2221 tttggtgcct ttgttaacct ctttgacaag acagatgcgc tggtgcatat ctctgaaatt
     2281 gcttggagcc gcactaccaa tgtctcagat gttcttgaaa tcggtgaaga ggttgacgtt
     2341 aaggttatta aggttgatga taagggacgt attgacgcat caatgaaagc cttggtgcca
     2401 cgcccgccaa agccagaaaa atcagaagca aaaaaagaag gcaaacatga ctaatacaaa
     2461 tgaactagat attcgtttaa gagcctttat caatgcccct gataattttt tagatagcgt
     2521 ggccttggtt aatgcttttc accagtatcc ggtgtgggca gcaaaaaagc cctatgctat
     2581 tgagattgaa ggggtaagga tttttcctgt attcacagat aaggacgaca tggcgacctt
     2641 taaagaggag caaaagagtg cacaagctca gtattgggta gagcgctctg ctcttactgt
     2701 cttggaggag gctgttcatg caggtgctgc tgggctaggc tttaatctca agaaaaaggg
     2761 agattttggc aattctacag tgttcaagtc tgctgatatg attcagttta tgaacaatta
     2821 cacaacgatt ttgaatacct tgatgagtga tgacaatagc gcagcagata ccctggatag
     2881 gctttatctg gtgccggcct ttgtttaccc taaggaagag gagcattact atgacaggct
     2941 ttttccaacc atgtcaactc cagaggggaa gcgttatgtt cctgcctttt caaatcttca
     3001 gagcttcgct aaatggtaca atcaagagga gtttggcggc ctttttagga aatcaggtgg
     3061 tgttatctta acatggaaga tagcagacat ttatcagcca agaaatggca ataatgacat
     3121 agacgagacc tttggggttg ctattgaccc ctttgatgat cagcagattc ttgttgattg
     3181 gtctgatatt gacacataaa aggagtttaa atgggctggt ggaaggacaa tattgatatt
     3241 gtaaagcaac tagatcctgc tgcacgtagc accctagagg ttatcctaac ctaccctgga
     3301 ttaaaggcct tggcagcgca caggctgtca cattttttgt ggcagcatgg ctttaagctg
     3361 ctggctcgaa tgcatagcca gttttggcga ttttggacac agattgaaat ccacccagga
     3421 gctaggattg cttcaggtgt tttcattgac catggggctg gcttggtgat tggtgagacg
     3481 gccattgttg aaaaaggagc catgctttat catggagtga cgcttggtgg aactggaaaa
     3541 gatcgaggga agcggcaccc tactgttcgt gagggggcac tgatttctgc ccatgctcaa
     3601 attatcggtc ctgtcgagat tgggaaatcg gctaaggttg gagctgcagc tgttgtgttg
     3661 actgatgtac ctgctggcgt gacggtcgtt ggcattccag cccaaattgt tcgagtgcat
     3721 gagaaaaagc cctcaaggca ggattaatag ttttctctag aggcagtcag ccaaaaaacg
     3781 ggagagttag agccctatgc ttacctcagt tgctgacagc ttgcgcagtc taggagaaaa
     3841 ggataaaaac aaaagggaaa agtgatgata aaaatctatg ataccatgac cagaagtctg
     3901 cgagagtttg taccaataac tgataaggtg gtcaatatgt atgtctgcgg gccaacggtt
     3961 tacaattata ttcacattgg caatgcacgt tcggctgtgg cctttgatac gattcgtcgc
     4021 tactttgaat acgcaggcta tacagtcaat tacatttcaa attttacaga tgtagacgat
     4081 aagattatca aggcagccaa ggaatcaggt gtatcaccca aggaattggc ggacagattt
     4141 attgctgcct ttatggagga taccaaggca ctcggtgtga agccggccac caaaaatcca
     4201 cgcgtcatgg actatatgga cgagatcatt gcctttatcg ctgctttaat caaaaaaggc
     4261 tatgcctatg agtcggcagg tgatatttat ttccgcgtgg caaaggcatc aaattatgcc
     4321 agactggcta ataaaacgat tgctgatttg gaggctggtg ctagtggtcg tacagatacc
     4381 gaaactgctc tcaaggaaga tcctttggac tttgccctat ggaaatcagc aaagctaggc
     4441 gagatttctt gggcaagtcc ttggagcgcc ggtcgtcctg gctggcatat cgagtgctct
     4501 gtaatggcaa ccgagctttt gggagatacc attgatattc atggtggtgg cgcagacctg
     4561 gaattcccac accataccaa tgaaattgct caatcagaag caaaaactag caaaactttt
     4621 gccaattact ggatgcataa tggctttgtt aatgttgaca acgaaaaaat gtctaagtca
     4681 ctgggcaact ttgtgactgt tcatgatctg ctaaagacgg tggatgggca aacgctacgc
     4741 tttttcttgg ctactcagca ttatcgtaag ccgattaatt ttactgaaaa agctattcat
     4801 gatgctggag ttaacctcaa atacttgaaa aacacgcttc agcagcccac agtagccact
     4861 gcagatgcta gccagcttgc tgcctttatc actgccttca aagcagccat gaatgatgat
     4921 tttaatacag caaatgggat tacagtctta tttgacatgg caaaatggat taactccggc
     4981 gcctattctg aggctgtcaa atcagcattt gaagagatgc tagctgtttt tggcattgtc
     5041 tttgaagcag aaagcctaga cacagagatt gagcagctga ttgctgagcg tcaggaggca
     5101 cgtgccaatc gagattttgc aagggcagat gctattcggg atcagttggc agctcagggg
     5161 atcaagctgt tggatacaaa agaaggtgtg aggtggatac gtggctaatt cagttgatgt
     5221 caatttgatt aatggcattg cccttgcctt tgttggtgat gctgtttatt cttactatat
     5281 tcgtcgtcat ctgattttcc aaggccagac caagccaaat aagctccact accttgcaac
     5341 aaaatatgtt tctgcaaagg cacaggcttc tctgattcag gccatgctag aagcacaact
     5401 attgaccgaa aaagaaaaag acatctacaa acgaggccgc aataccaaca gccataccaa
     5461 ggctaaaaat gctgatgtag taacctatcg tatgtcaaca ggctttgaag ctattatggg
     5521 ctaccttgat atgacaggtc agacagaacg gctagaactg ttgatccagt ggtgtatcaa
     5581 gcaggtggag aacagtcctc aatcataatg atgaatcatc taaaacattc tctgtgtcac
     5641 tagcgatctg ccatcgctca aagtcatgag agtgttttta tgttgtgttt aaaagttatg
     5701 tcacaatata gatacacacg aaacataaaa taaatatttg taacaaaaac gtaacaaaac
     5761 tattgaaaaa ttttccgaat agtttataat gaaagagtca taataaaatg ataggagaat
     5821 gtctatgaaa ccaatgagaa acgtagcctt agttatttca gcaatgttac tgttaagctc
     5881 acaggccttt gtatcagcag tagcagcaca ggacaatcaa ccaaccatag cagttcaagc
     5941 acaggcagca gctgaggcca atgtcagtgc tcgtatgcgt tcagatcagc ccgttattga
     6001 agctaacatt gctaccagtc agccagttag ccaaagcact gaggctacta ttttactaaa
     6061 ggatgccaaa ggcaacgcga ttaatagcac agcctatacc atgcaggctg gtcaaagccg
     6121 gttttcagta tggtttgacc ttacgaacct aaaggttagt gattatagta tatcagtgag
     6181 tgttcctgat aaagaaaagg cctttagtgg tagctcagca cctattcatt ttgatggaaa
     6241 gccaaccaaa aataccccag agacagaaca gaaaaacagc aatccagtac cagctaataa
     6301 ccagcctaaa cccgctgcta gcggcagggt gacaagcact gagcaacccc aaaatgtgcc
     6361 tagcgcgact gctagcgcca atcatatgac aagaaccaat catcgatctg ataaggtcct
     6421 aaaggcaagc tcaagcaaca caccatcagc tgccaaatca atagactctg ctgagaaagg
     6481 caagggcatg ctttctgata gcacagccca agataaagag caaaaaggct ttccttggct
     6541 gctatcatct ctaattgcaa ttacagcagc tgctttactt gctcttgtca tcaaagctgt
     6601 tcacaggaaa taaaaagagc agcaagagct attttattgc tttcgtggta taataaaaac
     6661 catgaaagct aaagaaatca atgaaaccaa ggatattgtt tatggcgtcc atgccgttac
     6721 cgaaagccta ctagccaata ctggaaataa gctttacatt caagaggatc tgtgtggtaa
     6781 gcatgttgat cacatcaagg atttagccac tagtaagaag gtgtctatct cttggacaaa
     6841 aaagaaagct ttgaccgaaa tgacagcagg agctgttcat cagggctttg cgcttcgagt
     6901 gtcagccttt gcttatactg agctagatga gctgctagag ctggcacagc aggaggataa
     6961 tcccttgctg ctcatcctag atgggctgac agatcctcat aattttgggt ctattttaag
     7021 aacagccgac gcaacaggtg tttgtggtgt gattatccct aagcatcgtg ctgttggtgt
     7081 gacaccagtg gttgctaaga cctcaacagg agctgttgag catgttccaa ttgctcgcgt
     7141 gacaaatctt agccaagcat tggatcagct aaaagcaaat ggcttttggg tcttcgggac
     7201 agatgtaact ggtacaccat catacaagtg gaatacctca ggcaagctgg ctttgattat
     7261 tggcaatgag ggtaagggca tttcagctaa catcaaaaaa caggtagatg aaatgattac
     7321 cattcctatg atgggtcatg ttcagagctt aaatgctagc gttgcagctg ctattttgat
     7381 gtatgaagta tttagaaata aattatagat gaaaaaaaga ctattgctgg ttgatggcta
     7441 taacatgatt gccttttggg aatcaactcg tcagtttttt aagacaaacc aattggatca
     7501 agctagaagg atcttgctaa ataagctgaa caactatgcg cattttgatg atagtgacat
     7561 tatttgcgta tttgatgctc agtatgttcc aggacttaga cagcgttatg accaatatag
     7621 gatttctgtt atttttaccg aagaggaaga aacagctgat agctatattg agcggactgc
     7681 tgctgagcta aacaccgctc taaccatggt agaggtggct actagtgatc tgaatgaaca
     7741 gtggacgatc ttttcccaag gcgccttgcg tgtcactgct aaagagcttg agcagcgtgt
     7801 taatgctgtt aagtcggatt tagataagct gtcacaggat attgatctta aaaagcctag
     7861 actgggtccc tttgatcaag ggcagcttaa tcagctcaag gactttatga atcgattaga
     7921 tgattaataa gcttatcttg ctagcttttc taggtatgat tctccaggct gctagagcag
     7981 ctcatacgat ctaacggtga tcatttctga ggcagctggt tcttattgct ttcttagctg
     8041 atattttttt gttatactat gagaaaatca tttgattatt aaacgataat gacgttactt
     8101 gggagttcag atgacatttg tattgatgac agattcaaca gcggatttag attctttttg
     8161 ggcaaaggag cataacatcg atatagtagg cctaactgtt gaatgtgatg gcaaggttta
     8221 caagacggtt ggtccagata gattaacgag tgatgctttg ctagctatga tgaaaagtgg
     8281 gagccagccc aaaacaagcc agataaatgt tggtcagttt gaagagattt ttcgacatta
     8341 cgcagctgat aaccaagctc ttttatatat cgccttttct tcagtcctat caggtaccta
     8401 tcaaagtgct gtcatggcac gtgagctggt tttggaggac tatccggacg ctgtaattga
     8461 gattgttgat agcttggctg cagcaggagg agagggctat ttgaccatgc tagcctcgga
     8521 ggcgcgtgat aatggaaaaa gcctattaga aaccaaagcg ataatagaag gtattttgcc
     8581 tcgcttacgc acctatttct tagtagatga tctttttcat cttgtgcgag gaggacgctt
     8641 gtcaaaaggc tctgctttta taggcagcct agtgaatatt aagcctctct tatggattga
     8701 tgccagcgga aaattagttc ctattgccaa gattcgtggc cgtaaaaagg ccattaagga
     8761 aattgctgac agagccacaa aagatattgc tgattcaact gttgttgtgt cctatactag
     8821 tgatcagact ggggcagatg acctacgaga acagctatta gcacatgaag gtatcagtga
     8881 tgtctttatg ctgccgctcg gaccggtgat tgctgctcat acaggtccag ataccttagc
     8941 ggtctttgtc atcggcaagg aaaaaagata aaaagaaaag gattgaagcg cttgtttcaa
     9001 ttcttttttg tcgactatag cttgttttag ctgtgatgcc gcttaagagt atgggtgttc
     9061 gcatttttta tttttaatca aaagttagaa tgaattgttt gacaatgaag gtgcgcgtgc
     9121 aggtaaggaa ctagcataac agaacagggc tttttgattt gccagaagtc agatgtcaaa
     9181 tgttttagca gttgacagga gctttggtca ttccaccact aatctttgta ttgttatttg
     9241 cataggagct aacaggaact gagcggattt tttggaggga agtcaaggct aatagtccag
     9301 ctcaaaagca agcctgttct tcttgtgaaa aagcaaaaat aatcaaagaa atagagctaa
     9361 accacttgac tatcagttaa gaagtttgat actatagtag acggtattgt ttaccccatt
     9421 tgaaaggccc cggaaccttc caaatacctt cgatggaccg gaacatccat cactaatgta
     9481 aacaaaaacg aattcgtata ggagaaatca tgaacaaaac aactttcatg gctaaaccag
     9541 gccaagttga acgcaaatgg tacgttgttg acgcaacaga tgtgccactt ggacgccttt
     9601 ctgcagtagt tgctagcgta cttcgcggaa agaacaagcc aactttcaca ccgcacactg
     9661 atacaggtga ctttgttatt gttatcaatg ctgagaaggt taaattaact ggtaaaaaag
     9721 caactgataa ggtttattac actcactcaa tgtacccagg tggcttgaaa tcaatcactg
     9781 ctggtgagct tcgctctaaa aatgccgttc gtttgattga aaagtcagta aaaggcatgc
     9841 ttccacacaa cactcttgga cgtgcacaag gtatgaaatt aaaggtcttt gttggcggtg
     9901 agcacactca tgctgcacaa caaccagaag tacttgatat ttcaggactt atctaagaga
     9961 aaggagcatt aaataatggc acaagcacaa tatgcaggta ctggtcgtcg taaaaacgct
    10021 gttgcacgcg ttcgtttagt tccaggtact ggtaaaatca ctgttaataa aaaagatgtt
    10081 gaagaataca tcccacatgc tgacctacgt ttagtcatta atcagccttt tgcagtgact
    10141 tcaactgaag gctcatacga cgtttttgtt aacgttgtag gtggtggtta tgctggtcaa
    10201 tcaggtgcga ttcgtcatgg tatcgctcgt gcgcttcttc aagtggaccc agatttccgt
    10261 gactcactaa agcgcgctgg tcttcttaca cgtgacgcac gtatggttga acgtaaaaaa
    10321 ccaggtctta aaaaagcccg taaagctagc cagttctcaa aacgttaata tccagttata
    10381 ccaacgtttc agagcacttt gcgaagtttt cgcaaggtgc ttttttgttg aaaaaagcac
    10441 cttggtaatc tgttgagacc tagttttaag agaggttaag ttagaatgac tataagtatc
    10501 taaagtcatc tggctgctag catgacctag acgcttagcg gtattaactg ggtcaattcc
    10561 catttcaatc atcaaggttg cgtgagtgtg cctaaaccca tgtgggctaa tctttttaag
    10621 attatgcttt cgtataatgc gttttagaat attgttgata tagtcagcgt gtaagggttc
    10681 tatctcacca tctctgttgc agtatgtaaa cataaattct ttgtcgagag aaaggggctg
    10741 tactgataat tgcccctttt ctttgctagt ttcctgtttc catttgttga ggatagaaca
    10801 ggtttcatca tcaagataga tagagcgtac tgagaatgta tttttagttc ctttttcaat
    10861 ggcatgacca tctattcttc ctaaactttt gctgactgtt aatagttgat tctcagaatc
    10921 aaaatcttcc catttgaggg cgtagagctc tccttttcgt aacccgctgt atgctagtaa
    10981 tcgaaataga gcataatgtt tataaggttc attttctaaa atgattgtca aaaaatgatg
    11041 caactcgtta actgtccagt agttctcact gacagttttt ttgagtttag gcataataac
    11101 tttgctcata ggattacgtt caatatgatt catattgatg gcaaattcaa aggttttaga
    11161 ggtgtatgac ttgatttgct tcatgttctt gaatgatttc gctttatctg tgataaaggt
    11221 ttggcagtct agcggactga tttttgaaat ctttttctct ccaaaggttg gaagaatatg
    11281 aaggcgatat aaatcggccg ttttagctgc agtagttgtt tcaacggtat ctttgtaagc
    11341 ttcataccac ctttgatata gttcttggta agtataggtt gtttgagcag taagatgggc
    11401 aaaagttcca ctattcagct gatgattaac agcagtttca tgagctttgg cagctttacg
    11461 cgtcttgaat cctcgtttag tgtaatattt tttcttaccg tagtcgttta gaccaaggta
    11521 aactttaaca aaataggtaa ttccttttgt agattggtat ttgtgtacag acataacagt
    11581 tctccgtttc taagttttcg gagcttatgt aattgagaaa tattagtcta ttttctgtca
    11641 cgatctgctc gtctaatttg aaactcttcg gtttgtatcc atgttttcca aatatccgat
    11701 ttttggcctt ggttattcat aaacttaatt aagtctttga taaaggtttc ttcataatcc
    11761 attaagtagt tagaaagaat acgtctaaag tcatctgaga aaacctcgtt taagggcata
    11821 gacaaatgaa tctctcctag ttcgattcct ttcttaagct tctccatatc gcttttaaaa
    11881 ggtgttacag aagtaatttc agatgtcttg aaactatcag tgacgatttt taaatttgac
    11941 ggagcgtact tttcttcgtc aattccaagg atgtatgcca ctgagacacc aaaataatcc
    12001 gctaactttt gagcattctc ttttttaggt tttcgtattc cttggttata gctagatagt
    12061 gttgggtagg atatatctag cgcttcactg atacttttta tttttttgcc actttcttct
    12121 ataagtttag ctatattatt agtcatagat tcctcctaat tgatattcta ccacatttaa
    12181 tacaaaaagt ataataccac ttgacaagaa tacaaaaagt atttataatt taaaatgtat
    12241 aataaaatat acaaatttcg gagtttattt aattgagaaa tggaaacgag gtaatgatat
    12301 gtctgaagaa gcgactttag ttgttcaact tcccaaagtt ttggaaaaac aattaagggc
    12361 acattatgat gaaatggttt ctacagctat tgaaagagcg ctagaggata aagaattata
    12421 taaacctatg gttcggatgg cagccctttc tagatggctt gatgtgtcaa cgacaacact
    12481 tcaaaagtgg acgcgagaag gaatgcctac aatggttatt gatggtgtga ctctgtacga
    12541 taaacgtgcg gttacacgtt ggttgaagca atatgaaaga tgaggtaaag aatggctaat
    12601 agacgaatgt tgagtaaaac ggtggtgcag atacaacgat ttttacgcct accacttgaa
    12661 gcgcaggcgc tttactgtca cttggtagtc aatgcagatg atgatggtat tgttgaagct
    12721 tttcctgtta tgcggatgat taatgctaat gaggacagtt tgaatttatt aactcttaag
    12781 cagtatttac tcttgttaaa caatgaaatg gtttacttta tcaaggattt ctttgagcag
    12841 aataccatca aagcagatcg ttacacaccg agtagtcatc gtcaacttct tatagattat
    12901 ctgaaggata atcagttgtt ggagtgtcta aatctaggac cacgcttgat taattatctt
    12961 caaaatactc ggctccaagt tggagccagt ctggatccag atgggaaccg caatataatt
    13021 aaagataaga taagtaaaga taggataggt aaagataagt taagtcaaga taagatagga
    13081 ttagataatg atccaatctc atcacaactg actgatgaca tctggttaat ggaaacacta
    13141 tggcatcgag aattaaccca acaggagaaa gtattattag aaggattcgc ggttaatgat
    13201 tctttattgc agttagctat tcagaaaaca gaggagcttg agccaaagaa acaaaacatg
    13261 agttatgtca aagggatact aatgaattgg gaagctagag ggtttataac tgttgaccaa
    13321 gtgatagcat ctgaagaaga ctaccgtcca ttagaaattg caaatgtaga agtttcagaa
    13381 gatttcttag cagctatgga tatatggaaa gactagggga ataatgagtt atgacagtat
    13441 attatcaatt agaaaatatg ttagtggctg ggtttaagtc acaagatgag tacgaccgct
    13501 atcaggctct caagagggac tatgaagggg agtcagagga ctatagcttt tcaatcagag
    13561 aaatcacaaa tcaacttgaa atcatttgtc agacctcaga gaatgatttt ccgaacttat
    13621 cagaagcatt aatgattgat tatttagaac tggtaggaga gttgaaacga tatgatacta
    13681 atcaggcaga caggtattta gggatggttc gtcatgtctg aacgtatcag aactatttta
    13741 aagaagtttt atgtgacgga attgcagaat gaagtactta atcaactagt aaatgataca
    13801 ggcttgcaaa cattctctaa ttatgctcgt cggatgcttt ttaaggaaac atcactcttt
    13861 atgcgatttg atgaatctca gtttgatgag ttgatttatt ctttaaggcg tattcaaaat
    13921 aatttaaggc agttatctaa aattgcagag cagtctcaag atagtcaagc ctacagagct
    13981 atggactata gcagaaggtt agtttcacat tatgaaaagc agttaacgcg ttaccacaag
    14041 aaaaagaaac ggaaattatt atctaaggga gcttaatgga taaaaggaga attaggaacg
    14101 taattaaaca agtctttttg tctgaagaag aaaatcaaaa actgttagag aaaatgaagc
    14161 aagatggctt cacaaacttt tctctttttg ctagaaagca attattaaaa cctgattttg
    14221 aaacttggct agttagtttt ccagaatatc agccgctgac tggcaggtta ctatctgttg
    14281 gtagaacaat taatggcatc gctaaaagcg caacacagtt tggaaaaatt tcccaacatg
    14341 atttgatgga attaggtcag ttgatggagg aacttgtaga actggtagag aaacaagtga
    14401 aggaagacaa gcaacgaata gccaagaagt gatagtcgtt cagtcatttt ggtagaatag
    14461 ttttaaataa aacaacaaaa acgctgatgg tagtcagcgt tttttagcat gtaattgtaa
    14521 aaaatccttg tacggacaat gtgcggcacc gtataaagta cgggaaatca ctaaaaatgg
    14581 agttaggtct ttgcgagctc agatagtgta tacacactat cgtaaaaata gaaccatcag
    14641 taaaggtcag actgacactt tttgattgat gcttatattt tattttgggg caaagcccca
    14701 aaccccttga gaaaacgtgt gagaagtagg gaaaaatggt ataatagaaa tattaaagac
    14761 tgtgaggatt tgaagatgtc agaacaagca caaaggcaag agttgcaccg caaaatctgg
    14821 gcaatcgcag atgatgtccg tggtgcggta gatggttggg atttcaaaca atatattttg
    14881 ggaatccttt tttaccgttt tatcagtgaa aatttcaaga cttatatcga gggtggtgag
    14941 gacttcaact atgaggagat tccggatgaa gtaatcacac ctgaggttaa ggatgatgcg
    15001 attaagacaa aggggtactt tattatgcct gcgcagcttt tttccaatgt tgtgaaaaca
    15061 gctcgtagta atgacaactt aaatacggaa ctcaaggata tttttgatgc cattgaggcg
    15121 agtgctatgg gttatgccag tgaaaatgat attaaaggtc tttttgatga cgtagacacc
    15181 agaagtaata agctaggaag taccgtccca gagcgtaatg aacgcttagc ccttatccta
    15241 gaaggtattg ccagccttga ttttggtagt ttcgaggaca atcatatcga cctttttggc
    15301 gatgcctatg agtttctgat ttctaactac gcttctaacg ccgggaaatc aggcggagag
    15361 tttttcacac cgcagagcgt gtcacggctc ctagcacgta tcgtcatgtt aggcaaggat
    15421 gaaaagaaca aaatcaataa gatttatgac cctgcttgtg gttctggttc tctcttgctt
    15481 caagccaaaa aacaatttac ggagcatatt atcgaggatg gtttttatgg tcaggaaatc
    15541 aacatgacca cctacaactt ggctcggatg aatatgttcc ttcataatat caactacgac
    15601 aagtttagca ttgagcgtgg caatacgctg ctggacccta agcatggcaa tgataagccc
    15661 tttgatgcta tcgtgtccaa cccgccttat tcaatcaagt gggttggtag cgatgacccg
    15721 acgctaatta atgatgaccg ttttgcacca gcggggattc tggcacccaa gtctaaagcg
    15781 gattttgctt ttatcatgca tagcctttct tatttgtcca ataaaggcag agcggctatt
    15841 gtgaccttcc ctgggatttt ttatcgtggt ggagcggagc aaaagattcg tcagtatttg
    15901 gtagacggaa actttgtcga aactgttatc caattgccgg ataatctcct ttttgggacg
    15961 tctatcgcta cctgtatcct tattcttgct aagaataagc cgacaacaga tgttctcttc
    16021 attgacgcta gccagcagtt caaaaaagaa accaataaca atgtcttgac agaagagaac
    16081 atcgagaaaa ttctgaaaag tgttgagcat aagaataatg aagagtattt tgctcagctc
    16141 atttcccaag aaaaaattgt ggaagctgac tacaatctct ctgtatctac ctacgtggaa
    16201 aaagaggata cgcgtgagaa gattaatatt gatgtattaa acaaagaaat tgctgagacc
    16261 gtgaaaaata ttgaccgatt gcgggcagag attgataaga ttgtcgagga gttgagctga
    16321 tatgacctac attgatgaga tgattaaaga gctttgtcct gacggagtgg agtggaaaga
    16381 gttgggtgaa gtcgttgact acgaacagcc aacaaagtat atcgtaaaat ctaaggaata
    16441 cagcgatgat tattccattc cagttttgac agcaggtcag acatttattc ttggatacac
    16501 aaatgaagta actggtattt atccagcaag taaggaacat ccagttatta ttttcgatga
    16561 ctttacgaca gctagaaagt gggtggattt tgaatttaaa gttaagtcct cggcgatgaa
    16621 actactctct atcaagtcag accgtcaaga tgatgtttca ataaggtatg tttggcacta
    16681 tttaggaaca ataaaataca caccagaaca gcacgcacga cagtggatag ggactttttc
    16741 taaatttaaa atcccccttc ccccactaga aattcaaggg gagatagtta aaatacttga
    16801 caaattcacg gaacatgtta cagaattgac cgcagaattg accgcagaat tgacctttcg
    16861 acagaaacaa tattcttatt ttagagataa gctcctaagt tttgatgatg aaagtatggg
    16921 aggggcgaac gataaggttt acactgtcca gtggaaaacg ctgggggagg tggtgaattt
    16981 taggagaggg tctttccctc agccttacac agatatgtcg ttctatggtg gagaagatgc
    17041 ccaaccattt gttcaagttg tagatgttgc tgatgaagga tttagactga atactaaaac
    17101 gaaaaaaaca atttctcaaa aagctattcc aaaaagtgtt tttgtaccta agggaaccgt
    17161 tatcgttacc ttgcaaggca ccctaggaag ggtagcggtt acccagtatg atgcttatgt
    17221 cgatagaacg ttagcaattt ttgacggtta taagcaagaa gttgataaac gctatttcgc
    17281 acaccaattg aagtttattt ttgacagaga aaaagaattt gctagaggaa gtactctgaa
    17341 aacaataaca aaacaagaat tctcgaattt caaaatccca gtccctcctc tggatattca
    17401 gcgtcgtatt gtccaagttt tggataattt tgatacggtt tgtaatgacc taaatatcgg
    17461 gctacctaag gagattgagc ttcatcagaa acagtatgcc tattttagag acaaactctt
    17521 gaccttcacc gccgaaggcg tgtatactga cagtacagta cagacaagac ctaattaggc
    17581 tcttgacttg ggtttttgga ccgattaagg ttgagttggg ggctgtctgc gatgtggtgc
    17641 gtgggaatgg tttgcaaaag aaggattttg ttaatgaggg ttatcctgtt attcattatg
    17701 gacaaatcta taccttctat ggattgagtg ctcgcgtgac gaaatctttt gtgtcaccag
    17761 aagttggtca aaaattgaaa aaagctaaaa ctggtgatgt gattgtagct actacttctg
    17821 aaaatattga agatgttggt aaagcacttg tttgggaagg tgctgaagat gtttgtattg
    17881 gtggacactc ttgtgtattg cacacggaac aaaactcgaa gtacttgctt tattattttc
    17941 agacaactgt gtttcaaaag caaaaggaaa agttagtgat aggaactaaa gtgattgaac
    18001 tgtatcctaa aaatttagaa aaggcgatta ttattctccc acctgtatac gaacaagggc
    18061 gtatcgtctc cattcttgac aaatttgata cactaacttc tgaccttacc caaggtcttc
    18121 cgaaagaaat tgagcaacga cagaaacagt atgagtattg gcgggattta ctacttaact
    18181 ttccgtagga ggaagaatag atatgggaaa tgatatcaaa tttgaa
//
LOCUS       DARYUW010000039        17960 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYUW010000039 DARYUW010000000
VERSION     DARYUW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17960
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            23..1681
                     /locus_tag="TVW11_001336"
     CDS             23..1681
                     /locus_tag="TVW11_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1365429.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            1850..2764
                     /locus_tag="TVW11_001337"
     CDS             1850..2764
                     /locus_tag="TVW11_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365430.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            2774..3805
                     /locus_tag="TVW11_001338"
     CDS             2774..3805
                     /locus_tag="TVW11_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365431.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            3817..4863
                     /locus_tag="TVW11_001339"
     CDS             3817..4863
                     /locus_tag="TVW11_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365432.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            4863..5798
                     /locus_tag="TVW11_001340"
     CDS             4863..5798
                     /locus_tag="TVW11_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1365433.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(6427..8109)
                     /locus_tag="TVW11_001341"
     CDS             complement(6427..8109)
                     /locus_tag="TVW11_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1365434.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(8111..8341)
                     /locus_tag="TVW11_001342"
     CDS             complement(8111..8341)
                     /locus_tag="TVW11_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1365435.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            8627..9325
                     /gene="tsaB"
                     /locus_tag="TVW11_001343"
     CDS             8627..9325
                     /gene="tsaB"
                     /locus_tag="TVW11_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1365436.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            9328..9753
                     /gene="rimI"
                     /locus_tag="TVW11_001344"
     CDS             9328..9753
                     /gene="rimI"
                     /locus_tag="TVW11_001344"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1365437.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            9743..10759
                     /gene="tsaD"
                     /locus_tag="TVW11_001345"
     CDS             9743..10759
                     /gene="tsaD"
                     /locus_tag="TVW11_001345"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1365438.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            10781..11809
                     /locus_tag="TVW11_001346"
     CDS             10781..11809
                     /locus_tag="TVW11_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1365439.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(12204..12473)
                     /gene="rpsN"
                     /locus_tag="TVW11_001347"
     CDS             complement(12204..12473)
                     /gene="rpsN"
                     /locus_tag="TVW11_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1365440.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(12667..13839)
                     /locus_tag="TVW11_001348"
     CDS             complement(12667..13839)
                     /locus_tag="TVW11_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1365441.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            13965..14495
                     /locus_tag="TVW11_001349"
     CDS             13965..14495
                     /locus_tag="TVW11_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1365442.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            14540..15127
                     /locus_tag="TVW11_001350"
     CDS             14540..15127
                     /locus_tag="TVW11_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1365443.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            15231..15953
                     /locus_tag="TVW11_001351"
     CDS             15231..15953
                     /locus_tag="TVW11_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1365444.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(15995..16294)
                     /locus_tag="TVW11_001352"
     CDS             complement(15995..16294)
                     /locus_tag="TVW11_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1365445.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            16692..17279
                     /locus_tag="TVW11_001353"
     CDS             16692..17279
                     /locus_tag="TVW11_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365446.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            17418..>17960
                     /locus_tag="TVW11_001354"
     CDS             17418..>17960
                     /locus_tag="TVW11_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365447.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT         4967 a         3627 c         4205 g         5161 t
ORIGIN      
        1 attttgttag gaggaaggtt atatgacagt actaggaaca aaagcatgta agcgtctggg
       61 cttagcggca gttacgctag cctctgttgc tgccttgatg gcttgtggaa ataagcaatc
      121 agcgtcaaca gacaaaaaga gtgagattaa ttggtatacg ccaactgaga tcatcacact
      181 tgatatctca aaaaatacag atacctattc tgctttggct attggtaatt ctggcagtaa
      241 ccttttgcgt gctgatgcta aggggaaatt acagcctgat ttggctgaaa aggttgatgt
      301 gtcagaggac ggcttgacct atacagcaac cctgcgagat ggcttgaaat ggtctgatgg
      361 tagtgatcta acagcagagg actttgtgta cagctggcag cgaatggtcg atcctaagac
      421 agcctcagag tacgcttact tggcaactga gtcacatctg aaaaacgcag aggacattaa
      481 tagcgggaaa aatcctgatc tagactctct aggggtaaag gctgatggga ataaggttat
      541 ttttacctta acggagccag caccacaatt taagagcttg ctgtccttct ctaactttgt
      601 tcctcaaaaa gaatcctttg tcaaggacgc tggcaaggac tatgggacaa catcagaaaa
      661 acaaatttat tctggtcctt atattgtcaa ggactggaat ggcactagcg gaacctttaa
      721 gctagtaaag aataaaaact attgggacgc caaaaacgtc aaaactgaga cagttaatgt
      781 tcaaacggtt aaaaagccag atacagctgt tcaaatgtac aagcaaggta agctagactt
      841 tgcaaatatt tctggtacct cagctattta caatgctaat aaaaagcata aggacgttgt
      901 tccggttctt gaggcaacaa cagcctatat cgtatataac cagacaggag ctattgaagg
      961 cttgaacagt cttaaaattc gtcaagcctt gaatttggca acagaccgta agggaattgt
     1021 atctgcggct gttgatacag gctcaaagcc ggctacagcg ctggttccta caggtcttgc
     1081 taaattatct gacggaacag atctaacaga gcatgtggca cctggctata aatacgatga
     1141 caaggaagct gcaaagctct tcaaggaagg cttggcagag ctgggcaagg atgccttgac
     1201 aatcaccatc acagctgatg ctgatgcgcc ggctgccaag tctgcagtgg attacatcaa
     1261 ggaaacctgg gaaacagctc ttcctggctt gaccgttgaa gagaaatttg ttcctttcaa
     1321 gcaacgtctt gaggatacta aaaaccaaaa ctttgaggtt gcagttgttc tttggggtgg
     1381 tgattatcca aaagggtcta ccttctatgg cttgtttaaa tcagggtctg cttataacta
     1441 tggtaaattt acgaatgcag actatgatgc ggcctacaac aaggctctaa caacagatgc
     1501 cttgaataca gatgcggctg ctgatgatta taaggcggca gaaaaagccc tttatgacaa
     1561 tgccctttac aatccccttt acttccgtag cggtgaaggc ctgcaaaatc caagcatcaa
     1621 aggtcttatc cgtaattcaa ctggtctaaa tgttgacttt acttacgctt ataaggacta
     1681 gcaataatat tattgtaagc ctatactgac ctagcaaggc cacagctcct tgatgggaag
     1741 tgtttaagag aagcttaggg ctagctagga gtgtctatcc tgtaggcctt ggcaagcata
     1801 ttgcaagaat tggtcttaac cagttcttgc ttttggttag aggaaaaata tgattaaata
     1861 tcttttgaag cgagtggcta ttttagtagt gacactctgg gtggtgatta ccctgtcctt
     1921 ctttttgatg caggtgatgc ctggaacacc ctataacagt cctaaattaa ctgatgacat
     1981 gattgctatg ctgaatcagc agtacggctt agataagcct ctttggcagc aatatttgaa
     2041 gtatttgttt gatattcttc atggtgactt tggcaccagc tatcagtcga ttaatcaatc
     2101 agtgacaacc ctgatctcgc agcgtctggg ggtatctgtg cacttaggag tacaggcgct
     2161 tattgttggt attagctctg gcttagctgt tggtgctgtc tcagcgcgga ataaaaataa
     2221 tagcattgat gccattttaa gtgttatctc aacgcttggt atttccatgc cgtcctttat
     2281 cattggcttg ctgctgctgg attatttggg ctttaaatgg aatttacttc ccttgtctgg
     2341 ctggggaagc tttgggcaaa cgattttgcc gacgcttgct ttagctattc cggtctttgc
     2401 tcaggtgacc cgttttttcc gcagcgagat gatcgagacc ttatcgacag attatattca
     2461 gctagctagg gcgaagggct tgactaagcg tcaggtgact cgtcggcatg cttaccgcaa
     2521 ttcgatgatt cctgtgttaa ccttggttgg tccgatggct gctggtattt tgacgggatc
     2581 agccctgatt gagcagattt tttccattcc ggggattggg cagcagtttg tgacctctat
     2641 tcccaccaag gattacccag tgattatggg aacaacgatt gtctatgcgc taatgctgat
     2701 ggttgctatt ttggcaactg atatgatcat tagtatcgca gatccacgtg ttcgtttggg
     2761 ataggagagt gctatgctag aagaaacaaa atcatttaag cttgttggag caggtagctt
     2821 agcgacacaa gaaaaaattg aaaagccggc gctttccttt cttcaggacg cttggcgtag
     2881 gctaaagcac aataaactag ctgttattgc gatggggttt ttagctgtgc tgcttttgtt
     2941 ttctattggt tctttatttg ttgtatctac agatgatgcc aatagcttta acagtaagga
     3001 ggtaagcata taccgtaacc tgccgccaaa gctaagcagc agcttgccat tttggaatgg
     3061 gaccattacc tacgctggta atacagagcc caatgacgct tatgcggatc aaggggtccc
     3121 agaggacaag gccttcttac tcgggacgga taatctgggg cgcagtattg gaaaacgtat
     3181 tacggtaggg attcgtattt ctcttttgat tgctattgtc gcaaccctga tcgatctagt
     3241 gattggggta acctatggct tggtctcagg ctttgttggt ggcaagactg acatggtgat
     3301 gcagcggatc attgagatta tctcctctat tccaaacctt gttattgtga ccatgcttgg
     3361 tcttttgctt ggcaatggtg tgacttcaat tattatttca attgcgattg taggctggac
     3421 ctcaatggct aggcaggtcc gcaacctaac cctgtcttat cgagagcgtg atttcgtcct
     3481 tgcttctcgt gccttgggag aaagtaatat caggattgcc tttaagcatg tattgccaaa
     3541 tatttcaggg attattattg ttcaaatcat gatgactgtt ccgagtgcta tcatgtatga
     3601 gtcagtttta tctgcgatta atttaggcgt taagccaccg acagcttcga ttggttcatt
     3661 gattactgat gcacaagaaa gcctgcaata ttatccttat caggtgctgc tgccggcttt
     3721 tgccttggtg ttaatttcgc tagcctttat tttgttgggt gatggcttgc gtgacgcttt
     3781 tgatccaaaa tcaagtgatg aataggggga aataaaatga cgaatgaaac cattttaagt
     3841 gtcaaaaacc tccatgttga ttttaaaacc tacgctggag atgttaaggc gattcgtgat
     3901 atcagctttg agctaaaaaa gggagagact cttgcgattg tgggagaatc aggctcaggg
     3961 aaatctgtaa ccactcgcac gctgatgggg ttaaatgcta agaatgcaag tatttcaggg
     4021 aatatttgct ttaagggcaa gcagctcaat gagctgaagg aggaggaatg ggtcaaggtg
     4081 cgtggcaatg aaattgcaat gatcttccag gatccgatga ccagccttga tcctaccatg
     4141 acaattggca tgcagattgc agaggcaata atgattcatc aaagcattca taagacagaa
     4201 gccttgaagc gtgctttaga cctgatgcgt caggttggta tcccaaatgc tgaggagcac
     4261 cttaaggatt acccacatca gtggtctggg ggcatgcggc aacgggctgt tattgccatt
     4321 gctctagctg ccaatcctga tattttgatt gcagatgagc cgacaacagc tcttgatgtt
     4381 accattcagg cccagatttt gaagctgatg aaggatattc agtctcagac cgcatcatcg
     4441 attatcttta ttacgcatga ccttggtgtt gttgctggaa tggtagatcg cgttgctgtc
     4501 atgtatgctg gaaagattgt cgaatatgga acggttgacg aggtatttta tcatccgcag
     4561 cacccttata cctggggctt gctcaattcg atgccaacaa cagctactgc agcaggtagc
     4621 ttgaggtcta ttcccggaac gccgccagat ttattaaacc ctccaaaggg agatgctttt
     4681 gctgcccgta atgagtttgc cctagacatt gaccatatca aagagcctcc aatgttcaag
     4741 gtaagtgaca gccactacgc agcaacctgg ttgctagatg agcgtgctcc taaaataacc
     4801 cctccattcc caatccgcaa gcgttgggca aaatggcagg aaatggaaga gaggaaggct
     4861 taatgacaga agctcgtaaa aaattaatcg aagtaaagaa tgtttcctta acctttaaca
     4921 aggggaagaa aaacgaggtt aaggctattg atcgccttag ctttgacatt tatgaggggg
     4981 aagtatttgg ccttgttggg gaatcaggct caggcaagac gacagttggt cgagctattt
     5041 tgaaactgta tgacattagt gatggtgaga ttatctttaa cggagaaaat gtctcccaat
     5101 taaaagggaa aaagctgcat agctttcgta agcatgcaca aatgatcttc caagatcctc
     5161 aggctagttt gaacggccgt atgaaaatta gagacattgt tgcagagggc ttagacattc
     5221 atggcttgac agcctcaaag gcagagcgtg aagcaagagt ccaggagctg ttaaagcttg
     5281 ttgggctcaa tcagaaccat ttgacgcgct acccacatga attttccggt ggtcaacgcc
     5341 agcgaattgg cattgcgcgt gccttggctg tgaagccgac ctttattatc gcagatgagc
     5401 cgatttcagc gcttgatgtg tcgattcaag cacaggtagt gagtctcatg cagcaattgc
     5461 aaaaaaagcg tggcttgacc tatctcttta tcgctcacga tttgtctatg gtcaaataca
     5521 tttcagaccg tattggtgtg atgcattggg gcaaaatgct tgagattggg acatctgatg
     5581 aggtttacaa tcacccgatt cacccttata cgaaaagctt gatctcggcc attcctgagc
     5641 cggatcctga aaaggagcgt aagcgtattg cagaggttta tgatcctagc caggagctag
     5701 atggccaaga gcgacaaatg catgaaatca ctcctgggca ttttgtctta gcgactcagg
     5761 ccgaagccga gcagtaccga gcagagtgtg gcctttaaga gactagcata acagcaattt
     5821 cctaaaaagg ctgatgtgat agttttttag gtatgacaga ccaaaagtcg tatgaccttt
     5881 gccgatcaaa agcaggtgcc atgcgatttt ggtggtatgg tggagctttg tcagccaacc
     5941 tagactgcac aaaaagctcc ttatgataga atttgtagca tgaggttgcg acacaagtct
     6001 accctaaaat aaaacaaaat aaaacaaccg aacaggtcta gctttctgag atttcaaaag
     6061 ccagacctgt tcggttttta atgaatgaga ctaggtcata aagtatctta gttaagattg
     6121 tctaaagtgc agctcttttt gctgtgcttg ctgctgtttt tataaaatga ctcgtgggaa
     6181 tcaatcagcc tgtagtcaaa tgttatcgct ctctttttga gatgtggctt gacaggtttg
     6241 ctaagctcag caggctattt ttagtagtat agctagacaa aggcccttaa gctagctcag
     6301 cacgtcactc tgttaagctt agctaacagc acgtgttggg caagtagtat gcctcatagc
     6361 cttgtacgtc agtcattgac gttgacgcaa caaaaaaaca cgagtctcta agctcgtgtc
     6421 aaagatctat tggctatcag gcgttagaac catcggaatg ataataggct cgcgctctgt
     6481 cttttcgtaa aggaagggac gaagcgcatt aacgatagca ccattgacag actggatact
     6541 agcgtcctta tttttcagag cgatacgaat cgcattgaaa agcacgcgct gactctctct
     6601 gatgagctcg cctgactcgc gcatgtagat aaagccgcgg ctgagaatat ctggtccggc
     6661 taagatcatc tgtgtctcaa aatcaacagt cgccactgca aggacaaccc cgtcctctga
     6721 aagatcacga cgatcgcgaa ggactgctgt cccaatatct ccaatgccat tgccatctac
     6781 ataaatgtcc tgagcattga aatgaccggc tatacgagcg ctatcactgg tcaaggccaa
     6841 tacgtcacca ttttccatga taaagatatt ttcctctgga atcccaatat caacagcaag
     6901 cccagcatga accttctgca tacggtattc accatggaca ggcataaagt attttggctt
     6961 aataaggcta agcattagct tttgctcctg ctggccacca tgaccggagg tgtggatatt
     7021 gttgaccttt ccatgaataa cgtcaactcc agcctcctga atcgtattga ttagcttatt
     7081 gacgctgacg gtattaccag gaattggact tgatgaaaag atgacagtgt ctccaggctg
     7141 taagctgacc tgtctgtggg taccattggc aatcctagca agggcggcca tagactcccc
     7201 ttgactgccg gtacacatga tcaaaatctc actagcgtgg taatgtttaa tctcattagg
     7261 ctcaataaag gttccctttg ggaccttgat gtagccaagc tcaataccgt taacaatagc
     7321 cttttccatt gaacgaccaa atacagcaat cttacgccct gtcttaacag cggcttctgc
     7381 agcctgctgc aagcggtaga tatttgaagc aaaggaagca aaaatgatac gtccatgaat
     7441 gccttcaata atgttcatga ttgactggcc aacgaccttt tcagaattcg taaaggttgg
     7501 tatctcggca tttgtcgaat cggacaatag acaaagaacc ccgtccttac caagagcagc
     7561 catgcgatgt agatcagccg gatcaccaac aggtgtaaag tcaaacttga agtcgccagt
     7621 acagatgact ttcccttgtg gggtgtggat aacaatccca agtggctctg gaatagagtg
     7681 agttgtttta aagaaggtaa cgctcatatg cttaaaggtg agctcggtat tgtgattaat
     7741 ctcatagagc acagcatcgc gtaagagacc gtgctcctcc agctttcctc ggataagagc
     7801 tagagctaag gggcctgcat atataggcac attagcttgc tttagtaaaa aaggaatacc
     7861 gccaatatga tcctcatgac catgagtaat cacaagagcc ttgacgcgct ccaaattgtc
     7921 aacaatataa gagtaatcgg ggataacata gtcaatccct agcagatcgt cctctgggaa
     7981 tttgataccg gcatcgacaa tgatgatttc atcttgatac tcaataccgt aggtgttttt
     8041 gccgatctct cccagaccac caatcgcata aaccccaacc tcattaggcc ttaaactgat
     8101 atttgtcatg ttaaaactcc gttaatgtga aaacaccagt ttctttttcg tagtctaggt
     8161 gcttgtctga gagcagctcg atgaattcga cattgtaatc ggtgtgctct tcaaccatct
     8221 tgcgggcttt gatacgcccc tcaagctcac ttgcagcgtc tatatctagg tatagggcct
     8281 gtgtgttttc acgacgcgga ctgcgttcct ttgtttcttg gtagaaaact ttataaatca
     8341 ttgatgatat cttcctttca tgatgaatcg attatccaaa caataacaaa taggtcaaaa
     8401 cgagaaggcc tctgttttga cgattaccta tcatgtgatt attgtgtaat agatttaaac
     8461 ctgattctgt gcaattacta agattatacc atactatcgg cttttagtaa aaagtttcga
     8521 taaaattatt ctcttgaccg gtgatgaggc tgtggctgtc tccttttcca tgacctttat
     8581 tttatgttat aattgtggaa tagaaatgac ttgagaaggg cttagtatga agacacttgc
     8641 atttgacaca tcaaataagg cattatctgt tgctctatta gacgatggca cattattggc
     8701 tgatcttacg attaatgtta agaagaatca cagtattagt ctgatgccgg ctattgattt
     8761 tttaatgtcc tcagctgacc tgaagccaaa ggatcttgat cggatcgtag tagcagaagg
     8821 gccgggctcc tatactggct tgcgtgttgc tactgctaca gcaaaaatgc ttgcttatag
     8881 cctaagtatt gacctcgttg gcgtatcaag cctatatgcc ctagcggctt ctacttgccg
     8941 agaaaaccct gatagcttgg ttgtcccttt gattgatgct agacgacgcc atgtttatgt
     9001 gggctattat caccatcaaa aagctgtgaa acaggataag tacgcgtcct ttgatgctgt
     9061 tttagcagaa ctggtctctt gtgaccatgt gatttttgtt ggagaagtgg agggctttgc
     9121 agaggacatt cgatcagcct tgccagaggc caagataaag ccaagtctgc catcggcttt
     9181 tgaggttggt ttgctaggca gcagcctttc agctgacaat gtagcagcct ttgtcccaca
     9241 atatttgaag cgggtcgagg cagaggaaaa ctggctcaaa actcatgctg ccggtgatga
     9301 cagccagtat gtcaagcgag tttagcgatg atgtctatcc aagaaaaagc agcagctgtc
     9361 tatcaggtgc taaaagaggt ctatggtcaa tccccttgga ccttaaagca gatagtgtct
     9421 gatatgcagc aggagcatgt tgattatttt accttttatc atcaggagac cctgctaggt
     9481 tttttagcga ttcaacagct gccaggagaa atggaaatca ctaatctagc tgttttgcca
     9541 agctatcagg ggcaagggat tgcctcttgg ctcatgggac agctagatgg ctttgaggga
     9601 gtgatatttc ttgaggttag agcgtcaaac catagggcgc agcagcttta ccttaagcat
     9661 ggctttgagg tggtaggcca gcgtagcaat tattatcatg atccaataga agcagccttg
     9721 atcatgaggc gggaaggaaa gaatgacaga tagatatatt ttagcagtgg agagctcttg
     9781 tgatgagaca agtgttgcta tcttaaaaaa cgacaacgtc ttattgacca atattattgc
     9841 tagtcaggtt gaaagtcaca agcgttttgg tggagtggtt cctgaagtgg ctagtcgtca
     9901 tcatgtggag gtgattacga cttgctttga tgacgcactc aaggaggccc agcttgaggc
     9961 ttctgacttg actgcggttg cggttaccta tggaccaggt ctggtggggg ccttgctagt
    10021 tggcctagca gcagccaagg cctttgcttg ggctaatgat ttgcccttga ttccagtcaa
    10081 tcatatggca gggcacctga tggcggcacg cgagcaagga gagctggaat accctcttat
    10141 ggctctcttg gtttctggtg ggcatacaga gcttgtctat gtgaccgagc caggagaata
    10201 tcatattgtt ggagaaacac gtgatgacgc agttggtgag gcctatgata aggtaggacg
    10261 tgtgatgggc ttgccctatc ctgctggtcg tgagattgat cagctagctc accaagggac
    10321 agatacctat cattttcctc gtgccatgat gaaagaggat catttagaat tttctttttc
    10381 aggcctaaaa tcagccttta tcaacctgca ccataatgcg cagcaaaagg gtgaggagct
    10441 tgtgcttgag gatctctgtg cttcctttca ggctgcggtg ttagatatat tgttagcaaa
    10501 aacgaagaag gcactcaagc agtatccatc aaaaatgcta gtcgttgcag gtggagtggc
    10561 agctaatcag ggacttcgtg agcgtttagc tgaggaaata actgatatag ctgttgtgat
    10621 accacctcta agattgtgtg gagataatgc tggtatgatt gcgttggcgg cggtggttga
    10681 gtacgagaaa gggcatgtgg caggcttgga tctaaatgct aagccgagtc tagcctttga
    10741 tagctttcat cagcagtagt attagtatga ggagattgtc atgttttatt tattgcttcc
    10801 cccattgatt tgcagtgtgg tatttttggc tgtctatatt aaggagccaa gaacgctgtg
    10861 gctaggagct agctttgtga cgaccctagg tgttagtctc ttgtgtgcta tgatttacat
    10921 tttttcaatc gaagaaaagc ttcagggagt tggtatccta gtgctaggtg ttattgggtt
    10981 tcttgcgatt gtatggttga tgtctagtcc ctttatcctc ttgctctttc taagctttaa
    11041 tggcattagg ctcatcaaaa gagaggggct ttcctttcgg aatttattgc tgattggctc
    11101 agcggtgcta ttgtttgtac atccttttat cagcagacta ttgttagaga gtatcggtga
    11161 ttcaaagctt ttaaggatca tgtatgaaac gagtgacctc ttaatccttt acctcttgtt
    11221 aatcgtatca gtctacacca tctcaagcat gctgaatacc ttttacttca gaaaaaccaa
    11281 ggaggattat attattgtgc tgggcagcgg cttaaatgga gaccaggtca cccccttgct
    11341 agctagccgc attaataagg gcattcagat ttaccagaaa aatcctggca gcaagctgat
    11401 catgtctggt ggcaaagggg ctgatgagct aatagctgag ggtgaggcga tgtgtcgcta
    11461 tgcaatccag caaggaatca aaagtgaaga tatattagtt gaaaaccaat ccagaaacac
    11521 cagagaaaat attctgttgt ctaagcaatt aataccatct ggagcttcct tttgcttggt
    11581 gaccaatcgt taccacctgt ttagagcctt attactggct aaggagctag ccttgccttg
    11641 caggtgctat ggggcaaaaa caaagctcta ctttagtatg aatgccttta tcagagagat
    11701 tgttggctat ctccaattaa agaaaaagca gcacctgctg gcaatgctca tcttaacagt
    11761 aggctatata gccataagag tggtgatgat ctatatgctg cacatttgat gtcattggca
    11821 aaaaagctaa ggctagtcac ctcgtcttgg gctgaaaaag tctctcttag gtccttttct
    11881 cagatgatat gagcaagcag cctttttaaa aaggctacat ctaggatttt atggagcctt
    11941 agagcttgtt gtgtggtgat gttcaatgga accaatcaca attgttacag caaaaagcag
    12001 gcctttagga acgtttgctt tgctggtaag tccttttact tgcagaggct ggctacacca
    12061 gccaaaggct aaggcaagtg atttagcttg tgatgatcaa ggagttttaa gacgtaaaaa
    12121 aatagctcgg tatcttggca taccgagcta tcatgataaa ttggcttcta tgattactaa
    12181 atcttaaaca aggtgagtca agcttaccag ctagccttag tgattcctgg tagttggcct
    12241 ttgtgagcta gctcacgaaa attgatacgg ctgacaccaa acttacgcat gtaagcatgg
    12301 ggacggccat caattctatc acgatttttc aagcgatttg gatttgaatc acgtggcaat
    12361 ttgcgcagtg cttcataatc accctttgct ttaagctcgc gacgaaggtc agcatactgt
    12421 tcaatcagtt ggagctgctt atggtattta gcaatttttg acttctttgc cattgctttc
    12481 tccttcttaa tatttaataa tctcagagcg ttatcagcac cctgaatttc ctcaaccagt
    12541 cattaatcag ttaagaaaac atagctctat tatacactaa tttcaatcaa atgcaagaaa
    12601 aatagataac tgattaacca gttgaggcaa aaacagcctg ccagtgagtc tactgacaag
    12661 cctagcttag ctttgcgagc ttcctgccac ccagccagag cagagggcag ctgtaatgtt
    12721 aaagccacct gtatgagcat taacatctaa gacctcacca gcaaagtaaa gtcccgcgac
    12781 ctttttgctt tctagggtct tagggttgat ttcttttaag tcaatgccac ccttggttac
    12841 aaaggatttg gccagagata tttttcctgt gattggaatc ggtaattgct taatcctgtt
    12901 gacgagctcc tgagtctgtg tgggagttaa ctgctttcct ttttctggat agccctttgc
    12961 taaaaaatca gcgactcgct caggcatcaa agtcttgagc gcatttttaa gggccttttc
    13021 ccggtgctgc gctagatagc tgagcagctc agctgcggag gtttgtggca gcaggtcaag
    13081 ctctgcgatg tcacctccct taacaaagga ggaaagcctg agagcagcgg ggcctgacaa
    13141 cccaaaatgg gtaaaaagca aatcgtgagt gatctgatgt ttcccacagc taagggtcac
    13201 atcagcaagt gaaatcccct gcagagcctt atgtggaaag tctgttaata aggggctttc
    13261 cgcagcctct agctcggtga cagctatgtt aaagtggcga gcaatatcat agccaaagcc
    13321 tgtcgatcca gtagatgggt aggacttgcc tcctgttgcc acgataagcc tctcgcagct
    13381 gaaggtttga tcaactgatt tgaggtaaaa aaggttattc cgctttttga ccgagacaat
    13441 ctcggtactg atcagcacct gagctcctag tgacttgatt ttttgctcca gcgcattgat
    13501 aatcgtcttt gattgatcgg tcgtaggaaa catgcgtcca tgatcctctt ccttgagggt
    13561 caccccattt tccttgaaaa aggcaatgat gtcatgatta tcaaattggg aaaagacgct
    13621 atagagaaag cgcccgttac cgggaatgcc cgcgattagc tcatcatggc ttccgctatt
    13681 ggtgacattg cagcgtcctc ctccagtccc tgctagcttt ttgcctaggc gcttgttttt
    13741 gtcaagtagg agtgtcttgt agccatagta gctactagag atggctgcca tcataccagc
    13801 aggaccacct ccaataataa tcgtgtcgta tagtatcatg tgcttatttt agcataacat
    13861 caagcgattt aacagtaatg taaactaggc taaattgaca gaattctggt attgtgttac
    13921 tatttttaat aagaatattc agttacagta ataaagagga aattatggca atagaaaaga
    13981 cagttagtga actagctgac attttgggag tgagccgcca ggctgtcaat aatcgtgtca
    14041 agtccttacc agaggaggac cttgataaaa atgataaagg ggtcactgtc gttaagcgta
    14101 gtggcttggt taagctggag gaaatctaca agaaaaccat ttttgatgat gagccaatta
    14161 gtgaagagac caagcagcgt gagctcttag agattctggt tgacgaaaaa aacactgaaa
    14221 tcactcgctt atatgagcag ctaaaggcaa aggatagcca gctggctgct aaggacgagc
    14281 agatgcgtat taaggacgtt cagattgccg agaaggacaa gcagctggat cagcagcagc
    14341 agctgacagc taaggctatg gcagacaaag agaccttgaa gctggagctt gaggaagcaa
    14401 aggctgaggc tgatcaggta cgactgcaag cagaggagat acagtctgaa atgggaccta
    14461 aaaaaggttt tttaaatcgt ttatttggta aataacagta taccaagacc ctctaagggt
    14521 cttttttgag gagagaagaa tgaaacaatt agaagcatat attgcctttg atatggaatt
    14581 taatactgtc aatgaggtta gtcatatcat tcagctttca gcggtcaaat ggcacaagca
    14641 tcaggaggtt gacagctttg acagctatgt ttacactgct gttcccctgc aaagctttat
    14701 caatggcctg acaggcatta cctcagataa gatcgtatca gcacccaagg ttgatgaggt
    14761 gcttgatgcc tttaagcaat ttgtcggtga cacgcctttg ataggctata atgcacaaaa
    14821 gtctgatttg cctattttag cagcaaatgg cttggatctg tcagcgcaat atgcagtcga
    14881 tgtctttgat gaagcctatg agagacgaag cagcgaccta aacgggattg ctaatcttcg
    14941 cctgcaaaca gttgctgatt ttttagggat aaaaggaaga ggacataata gcttagagga
    15001 cgctcgtatg acagcgcgtg tctatgaagc gtttgtggaa tttgacgaca ataagtctta
    15061 cctaaacaaa caaaaagaag cgattgcaga taaccccttt gcagctctgg gagggctttt
    15121 tgactagcag cgctagtcat ttctctgaaa aagaaaaatg acctaaggtc agggcttgct
    15181 tgtgaccttg ggtcatattc tataatgagg acagaaagga ggtgaaggac atgtctgata
    15241 tttactcaac tggtgagcta gcaaaagcag caggtgtcac tgtcaggaca gtgcaatatt
    15301 acgataagcg tgggattttg ttgccttccc agcttactga aggtggacgg cggatttaca
    15361 ccgagtcaga tttggagcga ttgaaaatca tttgcttctt acgggaccta gatttttcca
    15421 ttgagcagat taagcgcgtg ctagcagaag acaatgttat ggcggtgctt gacctcttgc
    15481 tggtggatca tatccaacag ctggaacaag acttaaggac gaaaaagcat cagcttgaca
    15541 cagctgtcaa gcttttgtca ggtattcgct gctcatctag tcactctatc aaaaacctat
    15601 cagacatgtc acttaccatg aacaatcaaa aagcttggcg tcgtttgcag ttgaaaatgt
    15661 ttagtaatat tgccctagca atattggttc atgtgatgtt agtgttacta actagctatt
    15721 ttcatctatc ttggttggta tggatagagg ctccactatg gataatcttt tttactttat
    15781 tgatcgttta ttttcgtaaa caatttgagt acctatgtcc aaattgtcat actatttttg
    15841 aaccagactt taaagagttt gccttggcag gtcacacacc aaggacccgc aggctgacct
    15901 gtcctcattg ccatcaaaaa tcttactgcc ttgaattggc caaggaaaaa taatggaaaa
    15961 tctccgctgg atacccagtg gagatttctt gctattagaa tggtagcttg ccagcaaagg
    16021 ctcctagagt tttcttagtc gcctcatcaa tttgagcgag ggctgcattg atggcctgag
    16081 cagtcatatc ctgaagtgtc tctatatcct ctgggtcaac gactgcttcc ttgaaatcaa
    16141 tgctaaccaa ttgcttatca cctgtaaagg ttgcagtgac cagctcctga gctgactttc
    16201 ctgtaaattg catagctgct aggtcagcct gcttttgttc catttgcttt tgaagctttt
    16261 gcgcttgctt catcatgttt tgcatgttca tcataagttc caattctcct aagttttgat
    16321 acttaactat tataacatat cagacaagac ttcaaacatg tgatctttta aagttaatga
    16381 aaaggccctg ctagcctgca atgctttgat gtgctagcga ctaacgaaca ggtcgtttcc
    16441 tttaaataga gttttcttgt tgagctttat agctggtgct tgtttttgtg atgagcttgt
    16501 gtgaggctgt cgttagtgtt gttttaggtg gtttgacatc aggagcgatt aaaaaagtta
    16561 tcagtttaca tttttataat aataacttaa gaattaattt aactttagat taatcttact
    16621 ttatatttga ttgctatact tagtccataa cataaataac caaaaagaaa gaggtaatcg
    16681 ttatgacaac aatgactaca acaaaacaat caaagacaac tctagcagct cgttatttga
    16741 agcttggtct tacttcagca atgtttgctg gaggagcctt tctagctcta ggctcagcac
    16801 cggctgtctc tgcttctacc catgctggta atgatcagcc agcgactcaa cgcttaactg
    16861 atcaggagat ctacgaacgt gctcaaaagc tagacttgcc agactatgtg agaggctcaa
    16921 tctacggtat tctcaaccaa aactcaagtg ttacttatcc aaaggatata gcaggtctag
    16981 agcagtcaga agctccacaa ccccctgcag ctccacagct cactgaccaa gatgctcaaa
    17041 agctggactt gccagactat gtgagaggct caatctacgg tattctcaac caaaattcaa
    17101 gtgttactta tccaaaggat atagccggtt tagagcagtc agaggctcca caaccccctg
    17161 cagctccaca gctcactgac caagatgctc aacagctaga cttgccagac tatgtgagag
    17221 gctcaatcta cggtattctc aatcaaaact caagcattac ttatccgcgc gattattaag
    17281 catctaagat gattaaggtg cacaatcgac gattaaaatg attgatgagt taatgagatt
    17341 agaattattt ggctaagtta agaattagtg ttatacttga gagagtgtag cactaatttt
    17401 ttaatcaagg aggaagcatg acctacaaga tattattggt ggatgatgaa ttggaaatta
    17461 ttgatattaa cgaacgttat ttgcaacagg cagggtatcg tgttaccact gcaagcgatg
    17521 gtagtcaagc cttggagctt tttcataagg atcagtacga tttgattatc agtgatgtta
    17581 tgatgcccaa tatggatggc tatgatttta ttggggaggt tttactggaa aagccagatc
    17641 agccctttct ctttatcact gcaaaaacat ctgagcctga caagatttat tccttgagct
    17701 tgggagcaga tgattttatt tccaagccct ttagtccacg tgaattagtc ttacgggtca
    17761 aaaatatttt gaatcggatt tatggtaagg ctaaccaagc tgactcctta gttattgggg
    17821 atttggtcat ggatcacagc actcgaaggg ttacagtggc aaatcaagat ctgaatctga
    17881 ccaacaaggc ttttgatttg ttgtggattt tggccaatca tttgaatcat gtcttttcaa
    17941 aaacagagct ttatgagcgt
//
LOCUS       DARYUW010000040        17668 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYUW010000040 DARYUW010000000
VERSION     DARYUW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17668
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..1230
                     /locus_tag="TVW11_001355"
     CDS             <1..1230
                     /locus_tag="TVW11_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1365448.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TVW11_001356"
     CDS             1242..2744
                     /locus_tag="TVW11_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1365449.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TVW11_001357"
     CDS             2725..4302
                     /locus_tag="TVW11_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1365450.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TVW11_001358"
     CDS             4304..4510
                     /locus_tag="TVW11_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365451.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TVW11_001359"
     CDS             4507..4926
                     /locus_tag="TVW11_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1365452.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TVW11_001360"
     CDS             5123..5392
                     /locus_tag="TVW11_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365453.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TVW11_001361"
     CDS             5428..5595
                     /locus_tag="TVW11_001361"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365454.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TVW11_001362"
     CDS             5777..6400
                     /locus_tag="TVW11_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1365455.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TVW11_001363"
     CDS             6411..6791
                     /locus_tag="TVW11_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1365456.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TVW11_001364"
     CDS             6794..7843
                     /locus_tag="TVW11_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1365457.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TVW11_001365"
     CDS             7854..8120
                     /locus_tag="TVW11_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365458.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TVW11_001366"
     CDS             8130..8483
                     /locus_tag="TVW11_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1365459.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TVW11_001367"
     CDS             8480..8788
                     /locus_tag="TVW11_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365460.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TVW11_001368"
     CDS             8769..9134
                     /locus_tag="TVW11_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1365461.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TVW11_001369"
     CDS             9131..9520
                     /locus_tag="TVW11_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1365462.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TVW11_001370"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TVW11_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TVW11_001371"
     CDS             10183..10542
                     /locus_tag="TVW11_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1365463.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TVW11_001372"
     CDS             10584..10913
                     /locus_tag="TVW11_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365464.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TVW11_001373"
     CDS             10930..14184
                     /locus_tag="TVW11_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1365465.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TVW11_001374"
     CDS             14216..14995
                     /locus_tag="TVW11_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1365466.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TVW11_001375"
     CDS             14992..17049
                     /locus_tag="TVW11_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1365467.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..>17668
                     /locus_tag="TVW11_001376"
     CDS             17049..>17668
                     /locus_tag="TVW11_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1365468.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSG"
BASE COUNT         6001 a         3027 c         3941 g         4699 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgg
//
LOCUS       DARYUW010000041        17630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYUW010000041 DARYUW010000000
VERSION     DARYUW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            71..1321
                     /locus_tag="TVW11_001377"
     CDS             71..1321
                     /locus_tag="TVW11_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1365469.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1430..2311
                     /gene="truB"
                     /locus_tag="TVW11_001378"
     CDS             1430..2311
                     /gene="truB"
                     /locus_tag="TVW11_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1365470.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2325..3257
                     /locus_tag="TVW11_001379"
     CDS             2325..3257
                     /locus_tag="TVW11_001379"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1365471.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3300..3704
                     /locus_tag="TVW11_001380"
     CDS             3300..3704
                     /locus_tag="TVW11_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1365472.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3706..3984
                     /locus_tag="TVW11_001381"
     CDS             3706..3984
                     /locus_tag="TVW11_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1365473.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            3974..4750
                     /locus_tag="TVW11_001382"
     CDS             3974..4750
                     /locus_tag="TVW11_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1365474.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4767..6074
                     /locus_tag="TVW11_001383"
     CDS             4767..6074
                     /locus_tag="TVW11_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1365475.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6212..7078
                     /locus_tag="TVW11_001384"
     CDS             6212..7078
                     /locus_tag="TVW11_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1365476.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7089..8024
                     /gene="pstC"
                     /locus_tag="TVW11_001385"
     CDS             7089..8024
                     /gene="pstC"
                     /locus_tag="TVW11_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1365477.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8014..8901
                     /gene="pstA"
                     /locus_tag="TVW11_001386"
     CDS             8014..8901
                     /gene="pstA"
                     /locus_tag="TVW11_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1365478.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8918..9721
                     /gene="pstB"
                     /locus_tag="TVW11_001387"
     CDS             8918..9721
                     /gene="pstB"
                     /locus_tag="TVW11_001387"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1365479.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9735..10493
                     /gene="pstB"
                     /locus_tag="TVW11_001388"
     CDS             9735..10493
                     /gene="pstB"
                     /locus_tag="TVW11_001388"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1365480.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10564..11217
                     /gene="phoU"
                     /locus_tag="TVW11_001389"
     CDS             10564..11217
                     /gene="phoU"
                     /locus_tag="TVW11_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1365481.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11451..13988
                     /locus_tag="TVW11_001390"
     CDS             11451..13988
                     /locus_tag="TVW11_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1365482.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14407..15081
                     /locus_tag="TVW11_001391"
     CDS             14407..15081
                     /locus_tag="TVW11_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365483.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELSADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKEFDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15074..16384
                     /locus_tag="TVW11_001392"
     CDS             15074..16384
                     /locus_tag="TVW11_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1365484.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVGQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16769..17188
                     /locus_tag="TVW11_001393"
     CDS             16769..17188
                     /locus_tag="TVW11_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365485.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17185..>17630
                     /locus_tag="TVW11_001394"
     CDS             17185..>17630
                     /locus_tag="TVW11_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365486.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT         5296 a         3234 c         3944 g         5156 t
ORIGIN      
        1 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
       61 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      121 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      181 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      241 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      301 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      361 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      421 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      481 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      541 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      601 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      661 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      721 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      781 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      841 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      901 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
      961 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1021 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1081 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1141 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1201 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1261 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1321 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1381 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1441 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1501 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1561 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1621 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1681 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1741 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1801 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1861 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1921 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     1981 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2041 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2101 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2161 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2221 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2281 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2341 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2401 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2461 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2521 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2581 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2641 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2701 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2761 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2821 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2881 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     2941 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3001 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3061 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3121 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3181 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3241 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3301 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3361 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3421 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3481 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3541 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3601 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3661 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3721 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3781 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3841 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3901 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     3961 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4021 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4081 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4141 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4201 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4261 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4321 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4381 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4441 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4501 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4561 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4621 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4681 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4741 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4801 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4861 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4921 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     4981 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5041 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5101 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5161 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5221 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5281 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5341 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5401 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5461 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5521 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5581 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5641 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5701 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5761 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5821 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5881 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     5941 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6001 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6061 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaatttaaat aaaacttctt
     6121 ccaaagcatt gttagatatg ttaatataaa gaatatgctg aagcttaatt cttcgctata
     6181 aacctttatt tttatgaata ggaatagaat aatgaaatcg aaaaagaaat tctttttgtt
     6241 aagtctttta gccttgtcgg ctttcttttt gtcagcctgc tcaagctgga ttgataaggg
     6301 agaatccata acagcggtag gctcaacagc attacagccc ttagtagaag ccgcagctga
     6361 tgagtttgga agcaataacc tcggaaaatc tgttaatgtt caaggaggcg gctctggcac
     6421 tggcttatca caggtgcagt caggtgctgt tcaggtaggc aatagtgatg tctttgcaga
     6481 agaaaaggac gggattgatg ctgctaagct tgttgatcac caggttgccg tagcaggact
     6541 tgctgtcatt gccaatccta aggtcaaggt atctaatctc acaagcaagc agctacaaaa
     6601 gattttctca ggtgaatata ccaactggaa gcaggttggt ggacaggatc ttgctatttc
     6661 agtgattaat cgagcggcaa gctcaggctc acgtgctacc tttgatagtg tcatcatgaa
     6721 gggtgttact gctaagcaaa gtcaagagca ggattctaac ggtatggtta aatcaattgt
     6781 gtctcagaca ccgggggcca tttcttactt atcctttgcc tatgtggatt cgtctgtaaa
     6841 atcattacga ttgaatggct ttaaggccaa tgccaaaaat gtagcaacca atgattggcc
     6901 catctggtcc tatgagcata tgtataccaa aggcaagcca gacggcttaa ccaaggaatt
     6961 tttggattat gtgctatcag atgaggtcca aaaaaccatt gtgacacata tgggttatat
     7021 tgctatcact gatatgaagg tcgtcaaatc ctatgatgga aaagttacag ataaataatg
     7081 ggggaattat gaaaaatcag gaattagcta agcaattagc ctcaccatca aaaaattcac
     7141 gacttgaagc atttggtcgt acgattacct ttttttgcct cgccttaatt gtttttatcg
     7201 ttgcaatgat tttacttttt gtggctcaaa agggcttgtc tacctttttt gtaaacaagg
     7261 ttaatctttt tgatttccta tttggtacag agtggcagcc tagcgttaaa aatgctgccg
     7321 gtgttcctta tcttggagct cttccgatga ttgctggatc gtttttagtc acgattttat
     7381 cagccttggt ggcaacacca tttgccattg gggcagcagt atttatgact gaaatttcac
     7441 ccaagtacgg ggcaaaacta ttacagccag cagttgaatt gcttgtaggt atcccgtcag
     7501 ttgtttatgg ctttattggc ttgcaggttg ttgttccttt tattcgttct atttttggtg
     7561 gaacaggctt tggtatccta tcaggggtct gtgtcttgtt tgtcatgatt ttaccgacgg
     7621 ttacctttat gacaacagat agtctgcgcg ctgttcctcg tcattatcgt gaggcttcta
     7681 tggctatggg ggctacacgt tggcaaacca tttggcgagt ggttttaaat gcggctcgtc
     7741 ctggtatttt tactgctgtt atttttggta tggctagagc ctttggtgag gccttagcca
     7801 ttcaaatggt tgtgggaaat tcagcagtca tgccggcttc actaaccact ccagcggcta
     7861 cattgacctc tgtattgact atgggaattg gtaatacagt tatgggaact gttcaaaata
     7921 atgtgctatg gtcattagcc cttgtcttat tgctgatgag tctagctttt aattcccttg
     7981 tcaaattaat tacgaaagag agaaagagaa attatgaacg ctaaaaaggt tgataaagta
     8041 gcaactggta gcttgtatac tattgctgga attattgtag ctattttagc ttccctaatt
     8101 ctgtttattc ttgtgcgtgg cctacctcac atcagctggt cgtttttaac agggaaatca
     8161 tcgtcctatg aagctggtgg aggtattggg attcagcttt ataattcatt tttcttgctg
     8221 gtagtaacct tgattatttc cattccccta tcaacaggtg ctggcattta tttggccgaa
     8281 tacgctaaaa aaggacctgt gacaaatgtg attagaacct gtattgaaat cctatcctca
     8341 ttgccatctg ttgtggttgg attgtttggc taccttattt ttgttgtaca gtttgaatat
     8401 ggcttttcta ttatatcagg tgcccttgct ttgacggtat ttaatcttcc gcaaatgaca
     8461 agaaacgttg aggatagctt gctgcatgtg catcatactc aaagagaggc agggctagcc
     8521 cttgggcttt cacgctggga aacggttttt catgtggtta ttccagaggc cttgccaagt
     8581 attgtgacag gtattgtttt ggcttcaggt cgtatctttg gtgaagcagc tgctcttatc
     8641 tatactgcgg gtcagtctgc cccagcgctt gattggtcaa attggaaccc tttgagcgtg
     8701 acaagcccta tttcaatttt ccgtcaatct gaaaccctag ctgttcatat ttggaaggtc
     8761 aatagtgaag ggacaatccc tgatgcaaca cttgtttctg ctggtagtgc agcggtgttg
     8821 ttgattttta tccttatttt caatctatca gctcgcttta ttggcaagcg tattcatgct
     8881 aagatgacag cagcaaaata agacattgga gagattcatg acagaatata attggaacga
     8941 acgtcatatc attacatttc cagaagaaac gattgcccta gctactaagg atctgcatgt
     9001 ttattatggt agcaaggagg caatcaaggg gattgatatg caattcgaaa aaaataaaat
     9061 tacagcccta attggaccct caggctgtgg caagtcaacc tatctgcgca gcctcaatcg
     9121 catgaatgac accattgata ttgctagagt aacaggtgaa attttgtatc aaggcattga
     9181 tgtcaatcga aaggacatga atgtgtatga aatccgtaag cacctaggaa tggtctttca
     9241 aaggccaaat ccatttgcca agtctattta taaaaacatc acctttgctc atgaaagagc
     9301 aggagtgaga gataaaaggg ttttagatga gattgtcgaa acctccctca agcaggctgc
     9361 actatgggat caggtcaagg acgatcttca taaatcagcc tttacccttt caggaggtca
     9421 gcagcagcgc ttgtgtattg ctagggctat ttcggttaag ccggatatct tgttgatgga
     9481 cgaaccagct tcagcccttg atcctattgc aaccatgcag ctagaagaaa ccatgtttga
     9541 gttgaagaag gattacacca ttattatcgt tactcataac atgcagcagg ccgctagagc
     9601 aagtgattac actgctttct tctatttggg tgacttaatt gaatacgata aaacgcgtaa
     9661 cattttccaa aacgctacct gtcagtccac aaatgattac gtctcagggc actttggtta
     9721 gaaagaagga tatgatggca gaacctattt tacaaatcag agatctttct gtttactata
     9781 ataaaaagaa aaccttaaag gacgtgtcct tagattttta cccaaatgaa atcacagcac
     9841 tcattggccc ttcagggtct gggaaatcaa cacttttgcg ttccatcaat cgcatgaatg
     9901 acctgaatcc agaggtaacc attacggggt caatcgttta taatggacat aacatttaca
     9961 gtccaagaac agacactgtt gatttgcgaa aagaaattgg tatggtcttt cagcagccca
    10021 atccctttcc aatgtctatc tatgaaaacg ttgtctatgg cttgcgccta aagggcatta
    10081 gagataaggc tgttttagat cacgctgttg aatcctctct caaaggagcc tccatctgga
    10141 gtgaggtcaa ggataggctt catgattcag ctgttggact atcaggaggt caacagcagc
    10201 gtgtctgcat agcaagggtt ctggcaacca gccctaaaat cattttgtta gatgagccaa
    10261 catcggcttt agatcccatt tcagccggca aaatcgaaga gaccctgttc tcactaaaaa
    10321 aggattatac gatggttatc gttacccgct ccatgcagca ggcctcgcgc ttgtcagacc
    10381 ggacaggctt cttcttagag ggagaccttc ttgagtttgg tcctactaag gcaatgttta
    10441 tgaaccctaa gaggaaggaa acagaagatt atatttcggg taaatttggc taagggatct
    10501 tgtttgtagt ctaggtatcc gctctgttta ggataataaa tgaatcaata gaaagaaaaa
    10561 atgatgttaa gaactaaatt tgaagaagaa ttagacaagc tacacaatca gttttactct
    10621 atgggaacag aagtcttgtc tcaaatcaat aaaaccgttc gtgcctttgt cagtcatgac
    10681 cgcgaattgg ccaaagaggt gattgaggaa gacgatacca tcaatggatt tgaaacaaaa
    10741 ttagaaaaaa agtctcttga aattatcgcc ttacagcagc ctgtttcaaa cgatttgcga
    10801 acagttatta ctgttttgaa ggcctcaagt gatattgagc gtatgggaga tcacgctgcc
    10861 tctatcgcta aagcaaccat tcgcatgaaa ggagaagagc gtatcccgat tgttgaggag
    10921 catatcaact tgatggggaa ggcagtcaag cagatggttg aagaggcgct aaatgcttat
    10981 attaatgcag atgatgccaa ggcctatgaa attgctgctt cagacgaaat cattgataat
    11041 tatttccgcg aaatccaatc tctagctgtc gaagaaattc gcaagacacc agatgccgtc
    11101 tttgctggca aggaatactt ccaggttctc atgtatttag agcgtatcgg tgactatgct
    11161 cgtaatattt gtgaatggat tgtctattta aaaactggaa aaattattga attataagaa
    11221 agtatggtat aatgggggct gggtgaactt ctcagttcct cgttttatta tagcgattaa
    11281 aaggttttag aggctggagc ttcagctgag ctgactatca gctgtcaagc ttctagacaa
    11341 aatgaaagat aacaataagc tagtcgtcta agggactaga cggcaggatt gattatatta
    11401 agaatgtgac cttgtcccat cactaattta atgacatatt aaggagttgt atgaaaaaag
    11461 tagaacatct tattgaaaag tttattcctg aaaattataa tattttctta gacattaatc
    11521 gcagcacaaa aaccttcaca ggtaatgttg caatcaatgg tgaagcatta gataatcaag
    11581 tgtcatttca ccaaaaggac ttggcaatca atgccatttt acttgacaat gaagctgtta
    11641 gctatcatgt tgacgatgac aatgagcttg tgcgtgttga gctgccagag actggtatga
    11701 tgacgcttgt cattgaattt tcaggtaata ttactgacaa tatgactggt atttacccgt
    11761 cctattacac aaaagatggt gaaaaacagg aggttatttc aacgcagttt gaaagccatt
    11821 ttgcgcgtga ggcctttcca tgtattgacg agcctgaagc aaaggctacc tttgacttaa
    11881 gcttgacatt tgaccaagca gagggcgaga ttgctctatc aaatatgcct gaggtcaatg
    11941 ctgagcgccg caaggagacc ggtctttgga cctttgagac aactcctaga atgtcttctt
    12001 atctgctggc ctttgcctta ggagacttgc atggcaaaac aacaaaaagt aaaaacggga
    12061 caacagttgg tgtttatgca accaaggctc acccactgac ctcgctagat ttttcattgg
    12121 atattgctgt acgtgtcatt gatttttacg aagactactt tggggttcgc tatcctattc
    12181 cgcaatctct aaatattgct cttcctgatt tttcatctgg agcgatggaa aactggggct
    12241 tgattaccta tcgtgaaatt tacctgttgg ttgatggcaa ttcaacagcc cgcagcagac
    12301 aaaatgttgc tcttgttgtg gcacacgaga ttgcccatca atggtttggt aatcttgtaa
    12361 ccatgaaatg gtgggacgat ctttggctaa atgaaagctt tgccaatatg atggaatatg
    12421 tagccatcaa tgctattgag ccgtcatggc gtatttttga ggatttccaa acaacaggtg
    12481 tgccgctggc tcttaagcgt gatgcaacag acggtgttca atcagtccat gttgctgtta
    12541 atcacccaga tgagattaat accctgtttg atccagctat tgtctatgcc aaaggtagcc
    12601 gcttaatgca tatgcttcgt cgctggattg gcgataagga ttttgcggca ggtctgcgcc
    12661 tttactttga aaagcatcaa taccgtaata ctgtaggacg tgatttgtgg caggctcttt
    12721 cagaagcttc tggtaaagat gttgctgcgt ttatggacgc ttggctagag cagccaggct
    12781 atcctgtctt aacggccaga gttgacaatg atcagttgat tctcagccaa aagcagttct
    12841 ttattggtga ggcaagcgac caaaagagac tatggccaat tccactaaat gcgaactgga
    12901 aaggtcttcc tgacgtactg acagaggagt ccatcgttat ttcaggcttt agtcaattag
    12961 ccgcccaaaa taaaggaaca cttcgcttta atacagaaaa tacagcgcat tacattacag
    13021 attatcaggg acagctcttt catagcttag ttgatgattt gaagcatctt gacaacacct
    13081 ctgcccttca agtgattcaa gagcgccgct tgctggctga tagcggtctg atttcttatg
    13141 cagagctggt tgacttaatc gctcagctag atgacaaaaa atcctatatg gttgctgcag
    13201 ctgttcagca ggttattaga ggcttagagc agttcattga tgaaggaacc tcagcagagc
    13261 agtccttcaa tcgattgatt tcttctattt tccaagagga cttcaggcag cttggatttg
    13321 aaaagagggc aaatgaatct gatgaagatg aaatggttcg tcaaattgct ttacatcacc
    13381 tgttggttgg aggcaatcgt gatgtgatca agcaggccaa gactatcttt gaagcttatg
    13441 caaatcgtat cgaagccatt ccagcagcca ttcgccgctc ggtattggtg agtcagatca
    13501 agtattttga aatagctgac ttggttgatg cttattttga tgcttatgtt gcaaccaagg
    13561 acaacaatct tcgagctgat ttgagcgccg ccttagcaac aacagctaat ccatcaactc
    13621 ttaagcgcat tcagtacagc ttaaaggata aggatattat taagccacag gacttagcag
    13681 cttggtacag ctttttgctt gatcaggcct ctgcacaaga aagcatttgg cgttgggcta
    13741 gagaaaattg gaagtggatt aaggcttcac tgggtggtga tatgagcttt gacaagttta
    13801 ttatttaccc tgctaaccat tttaaaacag cagagcgttt agctgaatat aaggccttct
    13861 ttgagccaca gcttgatgat atggcgatta gtcgcaatat ttcgatgggg ataaatgaaa
    13921 tttcagctcg agttgccctc attgatagtg aaaaggaagc tatcgctaat gctttaagtc
    13981 agtactaatg atatcacaaa ggagctgggg accatcctca actcctttat tggtgtcaaa
    14041 gctactatct ttaagtaaca tttagatcaa agggtaattg ctgtagctta gtggcactgc
    14101 ctgtcagctt ttggcaaatg aggaggcttc aatcataagc agtggttaat cttagcgccg
    14161 taaattacta gttgatcaga gtcagagctt aggacggata ggtcatagag acaattcttt
    14221 gtctgtcagt tttataactt aagtaggtct ccagactaac tgtatgctta tgacctgtca
    14281 tgagcaatag tttagcaaag cttaagcttt ttgtgttatc gttagattag agaattcatt
    14341 tagtaaggta atccctaaag actacttgag cgaggctgtt agtctttaga gaattgaggt
    14401 atcataatga taaaactatt attagtagaa gacgatttaa gcttgtcaaa ttctatcttt
    14461 gattttttag atgactttgc tgatgtgacg caggtttttg atggtgacga aggactctat
    14521 gaggcagaaa gcggtattta tgatttgatt ctgttagatt tgatgctgcc tgaaaaggat
    14581 ggctttcaag tgttaaaagc cttacgtgaa aaagacatca aaattcccgt cttgatcatg
    14641 actgccaaag aaagcatcga tgacaaaggg catggctttg agcttagtgc tgatgactat
    14701 ttaaccaagc ccttttacct agaagaatta aaaatgcgga ttcaggcctt gcttaagcgc
    14761 gtaggaaagt ttaatgacaa gagccttaaa tttggcaacc tgactgtaga tactacccgt
    14821 aaagaggtac aggtcaatgg gcaggccata gagctattag gcaaggagtt tgatttacta
    14881 atctatatcc ttcaaaatca aaatgttatt ttgccaaaat cacaaatttt tgatcgtatc
    14941 tggggctttg atagtgatac cactatctct gttgtagagg tctatgtctc taaaattcgt
    15001 aagaagctta aggggacaga ctttgttaat catcttcaaa ccttgagaag tgtaggatat
    15061 atcttaaaag ctaatgaata aactaaaaaa aggattattg tccgataatt atacgcattt
    15121 ttttcatttc tttgctattt ttacaggcat ttttgttgtc atgaccatca ttattttaca
    15181 aatcatgagg tttagtgtct attccacagt agacagcagt ctcatttcgg tcggtcaaaa
    15241 tgccagcaac tatgctaata ggaccatggc gagaatatct tccttttatt ttgatgcaga
    15301 aaataacctt attcaggctc ttcctgaact ggaagcgtca aaatcacttg gctcctccac
    15361 cactaatatg gatattattt tatttagtgc taatgggacg atattgaact cctttgacgc
    15421 tttctctaat taccaaagct ttcgtttaga caaaagccag ctcaataaca ttgtcaccac
    15481 acagctgatg aatttttatg ggcaaaagga gaaataccat accctaaccg ttaaggttca
    15541 cattaaaaac tatccagcag tggcttatat gatggcagtg gttaatgttc agcagctgga
    15601 tactgctaat gagcgctatg aacagattat tatcatggtt atgattgtct tttggttaat
    15661 ttcgattttg gccagtattt atttggctaa gtggagcaga aagccaatta tggagagcta
    15721 tgccaagcaa aaaatgtttg tagaaaatgc cagtcatgag cttaggactc ctttagcggt
    15781 gctgcaaaat cgtttggaat cgctgtttag aaagcctaac gaaaccattt tagacaatag
    15841 cgagcatatt gcgtcaagcc tagatgaggt tcgtaatatg agaatattaa caactaatct
    15901 gttaaattta gccagaagtg atgatgggat caagccgcag ctagttgatg ttgatgcagc
    15961 cttttttgat actgtttttg aaaattatca attagttgca gaagagtcag gcaagcagtt
    16021 tatctcagtt aatcagatca ataggccctt aaagacggat aaggctttgc tcaagcagct
    16081 gatgaccatt ttgtttgata atgcgatcaa atacactgat cataacggtg tggttgaggt
    16141 caaggttaga acgaccgata agcatttatt gatttctgtt attgataatg gcccagggat
    16201 caaggatgat gataagaaaa agatttttga tcgcttttac cgagtggata aggcaagggc
    16261 acgccaaaaa ggagggtttg gactcggatt ggccttagcg cagcagatcg ttacctcatt
    16321 aaaaggaacg attaccgtca gtgataataa gcctaccggc gccatctttg aagtaaaatt
    16381 atagcactga gttcttgcta gcccataatc agtatgaaaa taacagtcac tagatcaaga
    16441 agtctagtga ctttttttat tgtcttcttt ttgctgttga ccaagcagtt gacaagaaaa
    16501 ttccaataga tagtttaaag ccaataaaac cattattagg cttgcattac aggcaggtat
    16561 caaacaaaga tatagaaaaa tataccataa aaaatctcat aaaagtgtca aaatggtaaa
    16621 aaattgccaa caatatgtcg atattatacc attattatag tataatattt ataatcgtat
    16681 cataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ttgcaacacc
    16741 ttatgataaa gcataaagga atacaagcat gatagtctac ctaaagcaac acaaaaatta
    16801 ctggaaatta gtcagcatag ccgctttaat cattatttta ggaggaatac taacaatgaa
    16861 ttggcttaat ggcgaagagc taaaaaagaa aaagtacaga caagagcagg atagggtagt
    16921 gaaatacata ggagagcata tagagctatg taatggtcag cctataacaa aaattgagtt
    16981 tatagaattt cagttagaaa ctgcaaccac cggaacttgg tcaataacaa caattgttaa
    17041 tgagaaatat ctgattcatt tttcagaaga tagattaggt gaagaaatac ggacttccta
    17101 ttattctcca aaagaattta agcaatacag tgaaaagatg aggaataata tgactaatgt
    17161 tgaaacaatt tattacgagg agaaatgatg attgatagag attataaaaa tatttcagag
    17221 gatgtgtata aggttgattc tggtaaagaa agagatccga ttcaagaagg atatccggtt
    17281 gccaatggaa aataccgcgt tcttgaagcc gaagataacc ccgacaatgg tatgcaggct
    17341 atggctgttg tgccaataaa agatggcaaa gaggatagaa gtcatatcgt cattgcctat
    17401 gccgggacaa atagcagtga tatacgcgat attgacaccg atattcaatc cgttgttttt
    17461 ggagatgatc aatacctgtg tacccatgag gagcctgatt cttttaaagt agtcaagagt
    17521 cagctaagta ctgctaaagc cttttccgac tacattagga caagctaccc taacgctgcc
    17581 atctcctata ccggacactc tctgggaggc tatctggcac tcatcacagc
//
LOCUS       DARYUW010000042        17213 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYUW010000042 DARYUW010000000
VERSION     DARYUW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17213
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            12..1622
                     /gene="nikA"
                     /locus_tag="TVW11_001395"
     CDS             12..1622
                     /gene="nikA"
                     /locus_tag="TVW11_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1365487.1"
                     /translation="MNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDVNPHR
                     YNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDGSDFN
                     AQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYDLSMI
                     RPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEKPKLK
                     EVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMSTRLL
                     LLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGLVPYE
                     YNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEWKKLG
                     IDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPENIALE
                     SLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYRKGDF
                     KTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            1700..2641
                     /locus_tag="TVW11_001396"
     CDS             1700..2641
                     /locus_tag="TVW11_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365488.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            2626..3432
                     /locus_tag="TVW11_001397"
     CDS             2626..3432
                     /locus_tag="TVW11_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365489.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            3420..4208
                     /locus_tag="TVW11_001398"
     CDS             3420..4208
                     /locus_tag="TVW11_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365490.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            4195..4875
                     /locus_tag="TVW11_001399"
     CDS             4195..4875
                     /locus_tag="TVW11_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365491.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            5174..5902
                     /locus_tag="TVW11_001400"
     CDS             5174..5902
                     /locus_tag="TVW11_001400"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1365492.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            5939..6496
                     /gene="frr"
                     /locus_tag="TVW11_001401"
     CDS             5939..6496
                     /gene="frr"
                     /locus_tag="TVW11_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1365493.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            6630..7487
                     /gene="cvfB"
                     /locus_tag="TVW11_001402"
     CDS             6630..7487
                     /gene="cvfB"
                     /locus_tag="TVW11_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1365494.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            7825..8334
                     /gene="msrA"
                     /locus_tag="TVW11_001403"
     CDS             7825..8334
                     /gene="msrA"
                     /locus_tag="TVW11_001403"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1365495.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            8331..8546
                     /locus_tag="TVW11_001404"
     CDS             8331..8546
                     /locus_tag="TVW11_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1365496.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            8649..9749
                     /locus_tag="TVW11_001405"
     CDS             8649..9749
                     /locus_tag="TVW11_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1365497.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            9796..10371
                     /locus_tag="TVW11_001406"
     CDS             9796..10371
                     /locus_tag="TVW11_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1365498.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQVPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            10426..11052
                     /locus_tag="TVW11_001407"
     CDS             10426..11052
                     /locus_tag="TVW11_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1365499.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            11401..11898
                     /gene="ybeY"
                     /locus_tag="TVW11_001408"
     CDS             11401..11898
                     /gene="ybeY"
                     /locus_tag="TVW11_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1365500.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            11879..12280
                     /locus_tag="TVW11_001409"
     CDS             11879..12280
                     /locus_tag="TVW11_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1365501.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            12416..13312
                     /gene="era"
                     /locus_tag="TVW11_001410"
     CDS             12416..13312
                     /gene="era"
                     /locus_tag="TVW11_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1365502.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGAFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            13551..13715
                     /locus_tag="TVW11_001411"
     CDS             13551..13715
                     /locus_tag="TVW11_001411"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365503.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            14319..14645
                     /locus_tag="TVW11_001412"
     CDS             14319..14645
                     /locus_tag="TVW11_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1365504.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            14656..15519
                     /locus_tag="TVW11_001413"
     CDS             14656..15519
                     /locus_tag="TVW11_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365505.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            15516..16658
                     /locus_tag="TVW11_001414"
     CDS             15516..16658
                     /locus_tag="TVW11_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365506.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
BASE COUNT         4773 a         3030 c         4145 g         5265 t
ORIGIN      
        1 tgaaaactaa attgaatgtg ctattgttat tcttttttgc tttgctgctg acggcctgtc
       61 aaaatgctaa gcaggcctct taccgtacgg atcagttgag gattgcttgg ggtgaggatt
      121 ttggtgatgt caatcctcat cgctacaatc ctgatcagtt tgttattcaa gacatggttt
      181 atgagggctt ggttcgatat ggtgacaagg gtaatattga gccggcgtta gcagagagct
      241 ggacgattag cccagatggc aaaacctata cctttaacct gagacaggct aaattttcag
      301 atggttctga ttttaatgct caaaatgtta aacggaattt tgattcgatt ttctctgagc
      361 agaataaggg caatcataat tggtttcact ttaccaatca attggatagc tacaaggctt
      421 tagatgatca tacctttgag attaagctaa aggaggctta tagcgctacc ttgtatgatt
      481 tgtcaatgat cagaccgatt aggtttttgg ctgatgctgg ttttcctgat ggcgatgaca
      541 ccaataagca caatgttaaa aagccgattg gtacaggtca atgggttgtt aaagagaaaa
      601 aggcaaatga gtacattacc tttacacgtc atgagagcta ttggggagaa aaaccaaagc
      661 taaaggaagt aaccatcaag attatgcctg atgctgagac aagagcctta gcatttgagg
      721 ctggggatat tgatttgatc tatggaaatg gtctgattag tcttgatacc tttgtgcagt
      781 atgctaagga caagaagtat gttactgatg tttctcagcc catgtcgact cgtttattgc
      841 tgttaaatgc taagcagtca gtgtttcagg acaagcgggt tcgtcaggca atgaaccatg
      901 cggttgacaa aaaggctatt gctaagcaca cctttagagg aacagagaca gcagcagata
      961 ccattttttc aaaaacaaca ccgcatgctg atgcgggctt agttccttat gaatacaatc
     1021 tccaaaaggc taaggacatg ctgacagccg ctggctggaa ggaaaaccaa gaagggatta
     1081 gggaaaaaga tggtcagcag ttgcgtttac aggtgcctta tatttcaact aaagcgacag
     1141 acaaggattt ggttgaatat ttccaaggcg agtggaaaaa gcttgggatt gatgtggtct
     1201 tgacagctat ggaggaggat gactactggg ctaatgccaa gacagggcag tttgatatga
     1261 tgctgaccta ttcatgggga gctccttggg atcctcatgc ttggatgaca gccttaacgg
     1321 caaaagcgga tcatggtcac ccagaaaata ttgccttgga gagtttgcca tcaaaggctg
     1381 agattgatcg cctgattaaa tctgttttga ttgagccaga tggggataag gtagacaagg
     1441 gctataagca ggtattgtca ttgttgcatg atgaggctgt ttatattcca ctcacctatc
     1501 agtcagttgt ttcagtatat cgcaagggag attttaagac aatgcgcttt gcaccagagg
     1561 aaaatgccct tccattgcgt tacattgaaa aaagtgctgc tgataaggca gtcaagaatt
     1621 gatagagcag aggaactggt tgtgagtgac tatcctgaca attcttgtct gatgtcttag
     1681 tgaagggttg agagaaaata tgatgaagaa gcttatttct acctttggcg ccttgctaat
     1741 gatttcgata gtgacctttg ttctggttaa gctatcctcc gctaacccgg cagagcagta
     1801 tttgcgccta tctaagatca gtattacacc agaagctctt cacaatgcta ggctctattt
     1861 gggcttagac aagcctttat gggagcagta tgtgacctgg ttatctgaca ttcttgtagg
     1921 aaattttggg acctcttacg tgttaaaggt ccctgtcctg cctttggtgg tggagcgctt
     1981 tttagcaacg ctaatgctaa gcttgacctc ttttttactg gtacttgtga ttgcctttcc
     2041 tttgggggta ggcagtggtt tgtttgagca ttccttgttt gatcggctgg tgcgtttatt
     2101 cagctttgtc gctgtgtcaa tgcctagctt ttggttgggc tatctcttga ttatagcctt
     2161 ttctgttaag ctaaatctcc tgcctgtgtc aggcaaggcg ggtgccagca gcctcatttt
     2221 gccgagtatt acgcttagct tttccttgat tgggcaatat actgccttga tacgaaaggc
     2281 aatcagtgag cagctaacga gtctgcatgt tgaaaatgcc aggctaagag gggttaagac
     2341 ctattatatt gttaagcatc acctgattag aaatgccttt cctgctattg caacaggctt
     2401 gagcttgacc tttgtttatt tgatgacggg ctctattatt gttgaggata ttttctcatg
     2461 gaatggtatt ggcagtctat ttgttatgag tctgaaagca gcagatattc cggttattca
     2521 ggcctgtatg ctcttatttg gtgctttgtt tttactacac catgtgataa ctcaagagct
     2581 agtgtctttt attgaccctc gtctgcgcaa gacaaaggag gaagcatgcc caaatacgta
     2641 attggttcag ctgttatgct attgctgttg tttatctgtg tcttgtttgc tccttatctt
     2701 gctccctttg atcctcatgc tgttgatgtt gctagtaagc tcatgccacc tagtcagcag
     2761 cacttattag gaactgacca attgggaaga gatgtgctgt cgcgcttgtt atatggggct
     2821 aagtattcct tgcttttggc ggttactatt agtttgttag agctatctat tggtgctgtg
     2881 gttggtttgg ttgtaggctg gtatcaagga aggctcgagg cagcttttct gtggctagct
     2941 gatgttgttt ctgcctttcc tagcttttta ctatcgctag ctacaatggg gatacttggg
     3001 cagggcatag gcaacatgat cctagctatt gttctggtag agtggctgta ttatgctagg
     3061 ctgatggtca cgatggtcaa aagcgctaag gcagagccat atgtcattag tgcgcagaca
     3121 atgggcttat ctgtgcggca tatcttaaaa aagcatatcc tgccatttgt ttatcggccg
     3181 attgtagtgt tggctttgat gaatattggc aatattattc tcatgatctc aagcttttct
     3241 tttttgggta tcggtgttca gcccaatgtg acagaatggg gaatgatgct gcatgatgca
     3301 aggagctatt ttaggacagc tctgtggctc atgatgtcac cagggcttgc cattttagtg
     3361 actgtgctag cttttaacag cctaggtgat tacgctgatg ctaaggggtg gaggaaaaca
     3421 tggaacggtt aattgttaat gatttatcgg cttataatgg ctctgatgtg ctattaagta
     3481 agctcaatct tgagttgccc ttggggagct ccttggtgat tgttggcagg agtggttcgg
     3541 gcaagaccct cttgactaag ctattaattg gtcaatgccc gtcgaatgta cagatgacag
     3601 ggaggattac ctgtcaagat atgagactag atcaattaga tgctaagcaa tggcagagca
     3661 ttagagggcg ccacatggcc tatatggtcc aaaatcctat ggcgatgttc aatccctttc
     3721 agaccattga ggctcatctc cttgaaacca tccgaagcca tgagagactt tcaaaaaggg
     3781 cctgtctaaa aagggctctg cctttcatgc gagagctcta tctagagcag ccagaggagc
     3841 tgctgaggaa gtaccccttt gagctaagtg gtggtatgct acagcgggta atgctagcta
     3901 ttttgttgtg cttagaccca cagattatca ttttagatga gcctacctct gctttagatg
     3961 atgccaatcg ttctaatatc atacggatgc tgaagttatt gcaggacaag ggaaaaacca
     4021 ttattacagt gacgcatgat taccaattgg cacagacttt gggagggcaa ctactggtga
     4081 tgagtaaggg aaaaatcatc gaacagggaa gtgttgagtc gatttttcat cggccaagtc
     4141 aggctgccac caaggagttg cttttgcaaa atcattatga tcggctgata cgctatgata
     4201 gagtttagac atgtttataa gagctttcat caaaagccag tgctaacaga ttgtcatttt
     4261 caaatggaaa agggtgagag ccttgggatt atgggagaaa gtggtagtgg caagacaacg
     4321 cttgctaggt taatcattgg gctagagcag ccgacagctg gtcaggtgct ctttcatggt
     4381 cagccctatt ctgtaaaagt atgtggacct cggattttac ttgtctttca ggatgcgcta
     4441 agatcagtca atcccctctt tactattcaa gagatattga cagaggccct ttctaaggac
     4501 tttgccttag aggaggttgt tcaaatacta gctgcggtcg gtcttgacgc cactcatctg
     4561 ggtaaaaagg ccagagagct gagtggtggt cagctacagc gtgtttgtat agcgagagct
     4621 cttttgttaa ggccggaggt gatcattttt gatgaggctt tgagtggctt ggaccctatt
     4681 acccaagggc agctattgga cttgctctat gagttaaagc aggagtatca actgacttat
     4741 atttttattg cgcatgatgc taatatctgt caggccattt gtcatcgtgt tctgctgctg
     4801 gagcagggga ggctagttgc tgtcagagat aaggagcctc agacttcttg tggcggcatt
     4861 gggctagata actaaaacaa atcatctctc aatatagcac gacttagaat ctagtctggc
     4921 ttgaggcttg attttaagtc ttttttacgg cgttttttgt catagttgtt ctggtttttg
     4981 tcgtattaat aggttataac tgtgctattc ggatacgata atgctctttt tataatgact
     5041 catctttttt gctgctcaaa gggatcttga taaaaggatc gtcaaaaatt tcgctttcct
     5101 ctcttgcatt ggtctattaa atttttttgt tttgtggtag aatggtaggg acaaaataag
     5161 gagatcataa atagtgaaac ctaaatatca acgtatttta atcaaattgt ctggcgaggc
     5221 cttggctggt gataagggtg ttggcattga cataacaacg gttcagtcga ttgctaaaga
     5281 gatcgcagaa gttcacaatt caggtgttga aattgctctt gttattggtg gtggtaatct
     5341 ctggcgcggt gagcctgctg cagaggctgg tatggatcgt gtgcaggctg attacacagg
     5401 catgcttgga accgttatga atgctctagt aatggctgat agccttcagc attatggcgt
     5461 tgatactcgt gtgcagacag ctattcccat gcaaaacgtt gcagagcctt atattcgagg
     5521 tcgtgcgctt cgtcatctgg aaaaggggcg cattgttgtt ttcggtgctg gtattgggtc
     5581 accttatttt tcaacagata cgacagcggc cttacgtgct gctgagattg aggcagatgc
     5641 tatcttgatg gctaaaaatg gtgttgatgg tgtctacaat gctgacccaa gaaaggacgc
     5701 aaacgctgtt aagtttgatg aattgactca tggggaggtt atcaagcgcg gtctcaagat
     5761 tatggacgcg acagcttcaa ccttgtcaat ggataatgat attgatttgg ttgtctttaa
     5821 tatgaatgaa gcaggaaata tcaagcgtgt ggtctttgga gagcatattg gcacaacggt
     5881 atcaaataag gcctgcgatt aggattttag agctaaagga ttaaggagaa aaacaatcat
     5941 ggcaaatgca attattgaaa ctgcgaaaga acgttttaca cagtcacatc actcactagc
     6001 acgcgagtat gcaagcattc gtgcaggtcg tgctaatgct agccttttgg atcgtattca
     6061 ggtggattat tatggtgcac caacgccgtt gaaccaattg gcttctatta cagtaccaga
     6121 ggcgcgtgtg cttttgattt caccatttga caaatcatca atcaaggata ttgagcgtgc
     6181 cttgaatgct tctgatttgg gcattacacc agctaacgat ggctctgtca tccgcttggt
     6241 tattccagcg cttacagaag aaacacgtaa ggaattagcc aaggaagtga aaaaggttgg
     6301 tgagactgcg aaggtttcga ttcgcaatat tcgtcgtgat gctatggacg aggctaaaaa
     6361 gcaggagaag gctaaggaaa tcactgaaga tgagttaaaa gccttggaaa aggatattca
     6421 aaaagcaaca gatgaggctg tcaaagagat tgaccgaatg actgctgaca aagaaaagga
     6481 attactttca gtttaagcgg cttatctgat cattaagcta gatcagctgc gtaacctaat
     6541 acacatcagg cataacagga taggtgacaa ggctaaaaag cagctgcttt ggacttgtcc
     6601 ctatttttta aaagaaagaa caaaaagata tgaatcattt attagcaaca gttatcactg
     6661 gcttagtaaa agaagaaaat agtcagtttt atcttgtcca aaaggagggg ctgagctttg
     6721 ctctagctaa ggaggaaggc agtcatagat taggagatat ggttaagggc tttgtctata
     6781 cagatatgaa gcaaagacta cgcttgacca cgaagcctat tgacgcaagg cgtgatcatt
     6841 atggctgggg cgaggtgacc actgtccgtc gtgatcttgg ggtgtttgtt gatactggta
     6901 ttccagataa ggagattgtg gtttccttag atgttttgcc ggagctaaag gatctttggc
     6961 ctaaaaaagg agacaggctt tatcttaagc ttgtggttga caaaaaagat cgtatctggg
     7021 gtttgccagc tgagccagag atatttcaaa ggcttgctag tccagcctat gataacatgc
     7081 aaaatcaaag cctgcctgct attgtctatc gcttgaagct atcagggacc tttgtttacc
     7141 tgccagaaaa taatatgctg ggctttatcc accctagcga gcgttatacg gagcctcgtt
     7201 tggggcaggt tttgaccgct cgggtgattg gctttagaga acgtgaccgt accctcaacc
     7261 tttcgctaaa gccgcgttcc tttgaaatgc tggaaaacga tgcccagatg attctgacct
     7321 atctcaagtc taatggtggc tacatgactc ttaatgataa gtcaagccca gaggatatca
     7381 aggcaacctt tgggatttcc aagggtcaat ttaaaaaggc cttaggtggt ttgatgaagg
     7441 ctaacaagat caagcaggac gtgacaggaa ctgagctgat atcataggga gctgtctgtc
     7501 tcttagccta taatcataag ctggatcggt gttgctaaga cttatccttt atcagtatag
     7561 ctagcttcct tattttgagt gtggagctta gctgatagcc tgttttaaag cgccaatcat
     7621 ttttgttgtc gaaaaagctc tgtgtggccc tcttgatcta gtagtggctg cttgacagta
     7681 ctgcttagtg ctaggcacta gttgggctga ggagtcttgt tactttgagt ctgtgacttg
     7741 ttttatatta agctttgcct ctggcaaggt tttttgttac aatgaaaatc actaatgtaa
     7801 ggacaaagaa agtggagatt aggtatggaa agagcaattt ttgcaggagg ctgtttttgg
     7861 tgtatggtgc agccttttga ggagcaggca ggtattttat cagtgagaag tggctacaca
     7921 ggagggcatg ttcacaatcc aagctatgag caggtttgct caaagacgac aggccatact
     7981 gaagctgttg agattatctt tgatccgagt ctgatcagct attcagattt ggtagagctt
     8041 tactgggctc agacagaccc gaccgatgcc tttgggcaat ttgaggatag aggagacaac
     8101 tatcggccgg tgatttacta tactgatgag cggcagcggg aaattgcaga gcggtccaag
     8161 cagaccctgc aggcctcagg gcgctttgac cagcccattg tgacaagcat tgaaccggca
     8221 gagccttttt atctagcaga ggactatcat cagggctttt atcaaaagaa tccagagcgt
     8281 tatgcacaaa gtagtgctat tcgtcatcaa tttttggagg agcattggca atgagaaagg
     8341 cgttttacac ttggctgatg gctcagcgca actcgacatc taataagcct gctgctttat
     8401 tagctgattt ggtttttgag gacccgacct ttccaaagca tacagatgat tttgagacca
     8461 tcagtcgtta ccttgaagag gaagcgagct tttcattcaa tctggggcag tttgaccaga
     8521 tttgggagga ttaccttagc cactagccat aggctagctc ttttaggctt taaagctggg
     8581 tcttattccc gatttatagc aaaatttgtt ataatagagt tacttataga tggaaaagga
     8641 agacaaattt gcattattcg actgacatta gcttgaatca cccagatgat ctgttagctc
     8701 tttttggtag caatgagcgc catttgaaga tgatagaatc tcacctcaat gttgtgattc
     8761 atgctagaac tgagcgagtt cagattattg gtgatgatga gcgggctgtt gagctagcgc
     8821 gtttgacgat acaagccctt ttagttttgg tggggcgtgg catggttatc aatacctctg
     8881 atgtggtgac tgcgctgtct atggcggatt cagataggct tgatcaattt gttgctcttt
     8941 atgaggaaga gattatcaag gacttttata gcaagccaat tcgtgttaag acgctagggc
     9001 aaaaggccta tgttgatagt atcaagcatc atgatgtggt atttggtatt ggtccggctg
     9061 gaacaggaaa gaccttttta gcagttacgc tagcagttac tgctttaaag cgtggtcagg
     9121 ttaagcggat cattctcaca cgcccagctg ttgaagcagg agaaagctta ggctttttac
     9181 caggggattt gaaggaaaag gttgatcctt accttagacc agtctacgat gccctttatc
     9241 agattcttgg taaagagcag actactcggt taatggagcg tgatattatt gagattgctc
     9301 ccttggctta tatgcgtggt cggaccttag atgatgcctt tgtgatttta gatgaggcgc
     9361 aaaacacgac catcatgcag atgaagatgt ttttaaccag acttggtttt cagtctaaaa
     9421 tgattgttaa tggggacatt agtcagattg atttgccgcg tcatatcaca tcaggcttga
     9481 ttgatgcagc tcaaaaattg caggccatca agcagattga ttttgtgcat ttttcagcca
     9541 aggacgtggt gcgtcaccct gttgttgctg agattattaa ggcctatgaa actgtaggtt
     9601 caaaagcaga gtcattaaaa agcagcccta atcagctgca acatcagact aaggctccag
     9661 atcggcctaa aacagagacg ggtcagtcta cgtcaggctt aacaacctat gaggtcattg
     9721 gagagctgcc taaagaagac aaatcgtaaa aaagagctct tcacctgaag agccttttat
     9781 gaaagtgagg gtatcatgac agagctattg caagcgatta tggctgatcc tgccaatcgt
     9841 gactatacca aaaaaggtat cgaaccactt tatgcagctc ctcagaccgc tcggatagtc
     9901 attgttggtc aggtgcctgg tattgtagct caggagacgc gtctgtactg gaatgatcgt
     9961 agcggagttc gcttgagagc ttggctgggt gttgatgaca ggacctttta tcagtcgggc
    10021 ttgtttggcg ttcttcctat ggatttttat tatcccggta agggaaaatc aggtgattta
    10081 ccaccgcgaa agggctttgc tgccaagtgg catggtccgt taatggcctt gatgcctcag
    10141 gttgaattgg tggtgctggt cggacagtat gcccagcaat attaccttgg tgaaggttgt
    10201 agacgcaatc ttaccgaaac ggtgcagcat tttgaggact atcttccgga ttattttccc
    10261 cttgttcacc catctcctag aaatcagctt tggttggcta aaaatgcttg gtttgaagag
    10321 gagctggttc ctgttttaaa ggataaggtg aggcagattt tacgcggcta gggcaggcag
    10381 tcatgctgtt aggtgagtta gatttttagg aaagggagag tagtagtggc aagctttttt
    10441 gaaaaactag cagagcatag gtatcttgag acagagcgtc tatgcctgcg tccagtgacc
    10501 ttggatgatg ccaaagccat gtttgattat gcttctgatg aagagactgt caggtatagc
    10561 tttccagcca atcagacaat tgaggagacc cgtcaagtca ttgcttctgt ctatctggct
    10621 agtccacttg gacggtgggg gattgtgtta aaggaaacag gagactttat tgggacgctt
    10681 gatcttcatc atatacagct ggatttaggt agagctgaga ttggctattg tcttcataag
    10741 catcactggg gaagaggcta tgcgacagag gctgtcaagg ctgtactggt cttgtgtttt
    10801 gaagctttag gcatgaattg tgtgattgct aagcatgata aagccaatcc ggctttggga
    10861 cgtgttatgg ctaaaagcgg catgtgcttt tcacatgaag agccatatgc taagcgtgat
    10921 caccttgatt ccaaccgttt tgtgacagtg ctgcactatt atttaaccaa agaagattat
    10981 gacaagcaga aatcactggc gtcagccaat aagccagatc gttacctcca caatagcttt
    11041 gagagcagct agtggtatct aagggaaagc cgtttaggat tagtttttag gcgatggaag
    11101 tggtctaaag gcttatctac tattgtaatc ctaggagtcc cagctatcta agaggactgt
    11161 attctgcgca gcaggctctg ggtattccag aaacagcagc tgctggggta tcaacgatct
    11221 tgtcattatt ccggcttctt ttggagcagg ctagactaat gcctgctttt tcttttttct
    11281 tgtggtataa tggaaagaaa gtactgaaat gatgttgaaa ggataagagg tatcaagctt
    11341 tttgacctag cagtgtggtg tttgtttgga cctgtcttgc taggacctct tcatataatg
    11401 atgtatatag agatgattga tgaaactaag caggtttctc aagagatgat ggagcaaacc
    11461 attgatttgc tcaattttgc tgccaaaaca attggtaaag aggacaagga aatggcggtt
    11521 acctttgtga ccaatgatag aagccacgcc ttgaatcttg aatatcgtga tactgatcgt
    11581 ccgactgatg tgatttctct ggagtacaag ccagagcttc cgatcgcctt tagccaagag
    11641 gatttggagc ttgatcctga cttggcaggt atgatacagg agtttgatgc ttatattggg
    11701 gagctgttta tttctgttga caaagcccat gagcaggcag aagcctatgg gcattccttt
    11761 gagcgtgaga tgggcttctt ggctgttcat ggttttttgc atattaatgg ttatgatcat
    11821 tacactcctg aggaagaaaa agagatgttt acgttacagg aagagatttt gactgcttat
    11881 ggcctcacaa gacaataata aacgcaaatg gaaaaacaga acagtaattg ccagcttaga
    11941 atttgctttg acaggggttc tgacagcctt taaggaggag cgtaacctaa gaagtcatct
    12001 tttgtcagcc ctgttagcct ctttggctgg gattgttttt ggtatttctg ctatagaatg
    12061 gctgttttta ttgctggcta tttttttggt gattacctta gagattgtca attcagctat
    12121 tgaaaatgtg gttgacttgg caagtgatta ccatttctcc atgctggcta agcatgccaa
    12181 ggatatggct gcaggtgctg tcctggtcat ttcaggctat gctgttttga cggggctgat
    12241 tatctttgtt cccaaaattt ggcgaatgtt atgccattaa aaaaatgaaa ggaaatgggc
    12301 tatcctgtgc gatagtgcag cgcaggaaag gagtataagc tttaggaaag caatcaggtg
    12361 aatagcctgc tgcttgattc ttaccttgac tgatccttta ggcccttagt agcttatgtt
    12421 taaatcaggc tttgttgcca ttcttggccg accaaatgtc ggcaaatcaa cgtttttgaa
    12481 tcatgtcatg ggacaaaaaa tcgccgttat gagcgataag gcgcagacaa cccgtaataa
    12541 aattatggga atctatacca cagagacaga gcaaattgtt tttattgaca cgccaggcat
    12601 tcataagcct aagacagcct taggtgcttt tatggtggaa tcagcctata gtaccctgcg
    12661 tgaggttgag acggttcttt ttatggtgcc tgctgatgaa aagcgtggta agggtgatga
    12721 tatgattatc gaacgcctca aggctgctcg tattccggtt attttggtga tcaacaaaat
    12781 tgacaaggtt cacccagacc aattattgga gcagattgat gatttccgta gtcagatgga
    12841 ctttaaggaa attgttccta tttcagcact tcaaggaaac aacgtcgaaa cgctcgttca
    12901 gctcttaaag gataaccttg aagagggctt ccagtatttc ccagaggatc aaatcactga
    12961 tcacccagag cgctttcttg tttctgagat ggttcgtgaa aaggtgcttc acttgacaca
    13021 gcaggaggtg cctcattcag ttgctgttgt ggtcgattcg atgaagcgtg atgaggtgac
    13081 tgacaaggtg catatccgag ttaccatcat ggtagagcgt gacagccaaa aaggcattat
    13141 tattggaaaa caaggcgcca tgctcaaaaa aatcggtaag ctggcaaggc gtgatattga
    13201 gctaatgcta ggcgataagg tctatctgga gacctgggtc aaggttaaga aaaactggcg
    13261 tgacaaaaag cttgatttag ctgactttgg ctataatcag aaggagtatt gatcgctcaa
    13321 agcaggctat gtcagcagag ctggttagca acccttatac tgattgccct tgtttggtaa
    13381 gctgcattat tggtagcaat aaggctgtct tgtcattaga tcgaatcctc atttaatata
    13441 taagattgct tatatgagaa catttaaaag gtgttctctt tttttgtttt caggaggtaa
    13501 ggctaaatat agaagaacaa taatcacaac acatcgtggt gtgttatctt atggatagca
    13561 tgactgttga tgctgaaaaa gcaagtcaat tggatttagg tatagaaaat gcagggtggt
    13621 ttcactttaa actaactacg gctataaaac tgaaacaggt tgagaaggtt tttctgttca
    13681 cagcaatttt taatagagta gatgagttta tatgagtaca aaatgagaag actagaaata
    13741 tttgttaaag caatcagtaa gccctctggt tattctttga acaggtaatc atgaatttgg
    13801 ttttggatac atttaaacga tttattagcg gttgtgtcga tgataccaaa cacacgataa
    13861 tgatttctga aaatgtcgtc gtaattaata tggcttccaa taagaataat agagtcatga
    13921 gaataacttt aaagtgcttg tacatttgat tagatgataa aaagaatgat tttatgataa
    13981 aataagtgtg agatttatac ctatagccta tttgtttgcc actgacaatt ttagcagctt
    14041 taaaaaggtg tctgttgaag tagtaattaa tatagacgct aataccatat cccaagagag
    14101 gtttatgtaa gatttgaatg attaccatgg ttctccgaac taatacaata tcatatgatc
    14161 aaaaaacgaa aggaaaacag gttacatttc tcaaatgcct ctatgacatc ttaaacagct
    14221 actgtgatac cattcaggat atgatagata ccatttgaga ctttaccgtc tcaatgcttg
    14281 tacttgtatt aagatataaa tagagaagga ggacgtcaat gaaatatgtt attttatata
    14341 agaataggtc agttgttaaa ttaccaatct ctgaaaccta tgatgtgaca acacattcat
    14401 ctaagcctca cacagtagta tttgttaccc taaaagggga atttggggca gctacgtcac
    14461 tgagacagat tgagggagaa agtgctggga aattaaaaag gtgtcatcgt caatatttca
    14521 ttaatgaatc gaaaatctct ggatttgatt atgctacgag aataataaag gttacagaca
    14581 gcaggatttc gtacaggaga agtctactga gtactgagtt acaggtgctc agtagactca
    14641 tttaaggagg gttctatgtt attagaatta aatcaattga gtaagagcta cggatcgaaa
    14701 aatattttgc gaaggattac tactcaattc accccaggcc tttacggact tttaggggct
    14761 aatgggacgg ggaaaacgac cttgctcaat ctcattagtc attttacgac tcctgatgaa
    14821 ggagagattt tactggatca caaacctcaa tcagaggaat tttatcagca tattggtttt
    14881 ttgcctcaac agtttagtta ttatggtcgt ttttctggtc gagactttct tctttatatg
    14941 gcagccttaa aaggaatacc taaacataaa gccaagcaag aaacggatga attgttaaaa
    15001 cttgtggatc tatatgatgt ccgtctgaag cggattgcct cttattctgg tggtatgaag
    15061 caacgtctcg gtattgccca ggccttactc aatgacccta aaatcttgat tttagatgag
    15121 ccgacagttg gattagaccc aaaagaaagg gtgaagtttc gcaatattat tagcgaattg
    15181 tcggccaaca aaattattat cttatcaact catattgtct ctgatgttga ggctattgct
    15241 aaggagatta tcattttaaa aaatggtcaa tttatccata agagtagtag tcaagaattg
    15301 ttgaaaacca tctttggcaa ggtctgggag ttttctgtct ctgatggttc gccgttacca
    15361 aggcatggtc agtatgctgt agtcaatgag aaactagttt catctagtcg tgtttttcgt
    15421 gtggttagtg atgagaaacc aaatcagttg gctcaactag tgtcaccaac cttagaagac
    15481 ttatacattt atcactttag agaggaacag gtgttatgaa agctctctta ccatttgaat
    15541 taaaaaaact gatccgaacc aaatcagttt tgggaatgtt tattgttagc ttattagcaa
    15601 tctttgggtt attttatatc aactttttta atggacaaat cagtggttct tcgatagata
    15661 aaattcatgg aagagatgct gttgagataa acaagcgatt tgcggaagaa cataccggtc
    15721 aattgtccaa tgagttatta attagaacaa tcaaagatta tactctaggt ggcagctcaa
    15781 aaaatcctgt cttcaatgtg tatggctact atgtaactag ccattttgat ccaaaattta
    15841 gagattatta ttttaatttg aaaaaagaag agactattga tttcagtaag atcaccccaa
    15901 aatctcaaac ggctcttggc tcttatcttc cctttaaaga gctgaagttg ggtaattttg
    15961 caccctggaa tcagcttttt ctggtcataa atagtgctta tatccttctt cttcttttgt
    16021 ctgtttactt catcgctcct gttttttccg gtgatactgc taaaaatatg aatcctattt
    16081 tattgacaac taggtatggt cgtaataaac ttacgatagc caagataata agtagttact
    16141 tgataagcac ctcagtgttt gttacttttt acgccataat attagcggtc tttgtttggt
    16201 attttggatt aagtggttgg gacacgagtg ttcaactcaa tctgtattgg attaacagca
    16261 atgtgaatat aatggctttt ccagaaaaaa tgactctttt gggaacattt atcaatctag
    16321 tcacctatca gtttattggg cttatcctga ttacggctat cactatcctt atttcaagta
    16381 aggttaagtc tccattgaca ggttttgcct tgtctgcggc tagtgttttt gtaccaagtt
    16441 ttcttatgga tattttccaa gcaggaatac ctcataaggt gttgagtatt ttatctgtat
    16501 caactgcgag tacaccaaac ataatgctta agcttgctta tgacggcttt tttggcagtt
    16561 tttgggttga tggattagtt attgtcatga ttagattagc ttttgcattt ctttgcttat
    16621 atttagcata cttatcaata aagagggtaa gtcagtaaca tcaatagcat cgttatctaa
    16681 actattttta ttgtcgttac tgcaaaagtt aagggcattc aatgaattct tgcaaggtag
    16741 ataggattga gaaagctatt ttgtgatcta gaacacctaa aggtatagaa attagctttt
    16801 ttctaagatg ataagggaag tggcatcaat tgagacgatg atatatcgtt aagaagcagg
    16861 aactagatga caaagtagcc tatgtagagg agagtcttca ggtggtaaaa ataacgaatc
    16921 atcaagtgag cagggcttaa caagagaaat agtagaagct catgttaaga aaattaccgc
    16981 agcctgtctg ggcttcttta aggctgttta tagataaaaa gaaaagggac tcggtattca
    17041 agtctctttc tggcttttag aaaatgtgat caacatacta gtaaaaaaga atgatcttta
    17101 aacgatattg ttatagagca tcatgtaaaa atcaattaga gcttggtgac tccagctctt
    17161 tttatatggc attgtttaga aaatttagat aggttattga tgattttaaa aat
//
LOCUS       DARYUW010000043        17087 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYUW010000043 DARYUW010000000
VERSION     DARYUW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17087
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(27..998)
                     /locus_tag="TVW11_001415"
     CDS             complement(27..998)
                     /locus_tag="TVW11_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1365507.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(1311..1751)
                     /locus_tag="TVW11_001416"
     CDS             complement(1311..1751)
                     /locus_tag="TVW11_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1365508.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(1748..2683)
                     /locus_tag="TVW11_001417"
     CDS             complement(1748..2683)
                     /locus_tag="TVW11_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1365509.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(3121..3534)
                     /locus_tag="TVW11_001418"
     CDS             complement(3121..3534)
                     /locus_tag="TVW11_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1365510.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(3632..4387)
                     /locus_tag="TVW11_001419"
     CDS             complement(3632..4387)
                     /locus_tag="TVW11_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1365511.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(4392..6887)
                     /gene="gyrA"
                     /locus_tag="TVW11_001420"
     CDS             complement(4392..6887)
                     /gene="gyrA"
                     /locus_tag="TVW11_001420"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1365512.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            7079..8062
                     /locus_tag="TVW11_001421"
     CDS             7079..8062
                     /locus_tag="TVW11_001421"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1365513.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(8267..9634)
                     /locus_tag="TVW11_001422"
     CDS             complement(8267..9634)
                     /locus_tag="TVW11_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1365514.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYGVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(9884..10486)
                     /locus_tag="TVW11_001423"
     CDS             complement(9884..10486)
                     /locus_tag="TVW11_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1365515.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(10487..11464)
                     /locus_tag="TVW11_001424"
     CDS             complement(10487..11464)
                     /locus_tag="TVW11_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1365516.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(11467..12726)
                     /locus_tag="TVW11_001425"
     CDS             complement(11467..12726)
                     /locus_tag="TVW11_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1365517.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(12738..13169)
                     /locus_tag="TVW11_001426"
     CDS             complement(12738..13169)
                     /locus_tag="TVW11_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1365518.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(13183..13776)
                     /locus_tag="TVW11_001427"
     CDS             complement(13183..13776)
                     /locus_tag="TVW11_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1365519.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(13748..14596)
                     /gene="prmC"
                     /locus_tag="TVW11_001428"
     CDS             complement(13748..14596)
                     /gene="prmC"
                     /locus_tag="TVW11_001428"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1365520.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(14593..15675)
                     /gene="prfA"
                     /locus_tag="TVW11_001429"
     CDS             complement(14593..15675)
                     /gene="prfA"
                     /locus_tag="TVW11_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1365521.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(15717..16286)
                     /locus_tag="TVW11_001430"
     CDS             complement(15717..16286)
                     /locus_tag="TVW11_001430"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1365522.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            16473..16658
                     /locus_tag="TVW11_001431"
     CDS             16473..16658
                     /locus_tag="TVW11_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1365523.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            16713..>17087
                     /locus_tag="TVW11_001432"
     CDS             16713..>17087
                     /locus_tag="TVW11_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1365524.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         4804 a         3754 c         3261 g         5268 t
ORIGIN      
        1 ttagtcctac tacttttatc tatttatcag ttacccatta ggctgtcaat caatcctcta
       61 aagaaatcaa taatttgctg aaggattccc tgtccagtct ttaaggcttc agtagcatca
      121 aagttcacgt tgatattttt aaaggtagat ccggcctttt caacaatact atcctttaaa
      181 gcattcagcg ttttggtgaa gttttcattg gaaatcacgc cactatttga gaggttaagc
      241 gcgaaattga taataaggtt aatctgatca ggtgttactg ccttggttaa cccataatga
      301 tctaaggttt ctgttacaat ttggcgcacc ttttcctcat taaccccttc tccagccttt
      361 gcgacagcag ctttaatatc agtaagcgca acatttagct tatctgcatc atagcctgtt
      421 ttacctgcat tttcggtatt gatattagat agggttgata gctcctcttg tgccagcttc
      481 ttgttttcct ctgggacttt ggcaccattt ttttcgagtg aataataaat accggctaaa
      541 gctgattctc cagtaactgg gattggtgca gctacagtaa tattggcatg ctcaatgccc
      601 aaggtcacag cggcgttacg atacatatct tgcgtcacct tagtgatatt ttcaggtgtt
      661 acaatagtta ccttaagcgt ttctttagct cccagctttt gaatcctaac tgaggaataa
      721 agctgtaggc tcggatcatc tgctacattc atgatactag cataggcagt tgtatttagg
      781 gtgcttaatt tgttatcaga agcactattg tagtgaagca aggccaaggt ttgctctctt
      841 tgctcagcag acagtgaata gcctaaaacg taatcaggct gaacataggt ttcatcaatt
      901 acctgttgaa cattattagc tgcagcgtgt actgtttgaa gcataaatac cgaagccaaa
      961 gccatactgg ctgctattaa tttcttttga taagtcattt ttctacctct tttgtgttat
     1021 aaattttcct ttacgagaat cctccagaaa agacgattaa agccaaagta tctaggtgcc
     1081 tagtaagacc gttttactta gctctgcaaa gggcaatatt cctagtcttt ttcaaaatct
     1141 aacgcctcta ttgtagcatt tttacctcaa taagacgatt aaaaagctga aacaaagcat
     1201 agctagaatg gccaagcact atttttacaa caaaaaaact agtgcataat ggcagcttag
     1261 atgtagctac tatcactagt ccaatgatta tcttatgcag caaccagtct ttatgatctg
     1321 aggttttctt gatggttatt gtcctttaaa tagaaataat aatgatcatc agttttgatg
     1381 acatagccat ttttaacctc attaatcacg tccttttgat caaactggta gtccttaggc
     1441 ggtaataact ctgaggaaaa aaggctatca taaggcacct caccattgta aaaatggtaa
     1501 tggtcaccat gagaggtaac aaaaccatca tccgagatag acacaataat ttgctctgct
     1561 gctatcccct cttccttgct aacttcatta ggacttttgt cagtctcttt ctttaaggct
     1621 ttgcaccttt tttccaattg atgagatgat tttagcttct tgcctgtgct atcttgggct
     1681 ttaaagtcac aagcggacaa aggaaataat agtaagatag tgaataacga taaataagct
     1741 tttttggtca tgtttcactc tccaatacac gatatagtgt ttctaaattc atttttaaat
     1801 gctctagata agttttttga tcagctggaa ccacctcaag cgggcttagg atatcaattg
     1861 ctacaccgtt actttgagcc aaggttttgg ctagcttatc tgaagcattt tcttcgacga
     1921 aaatcgtctt cacatcatat tttttgataa agcggtcaat ttgagctaat tggcgaggac
     1981 taggctcttg ctcaggagat atccctgcaa ttcccaattg ctttagatca aatctcttag
     2041 ctaggtagga aaaggctgta tgctgtgtca caaaggtttt cctacctaga gattcaaact
     2101 tttccttata ggtcttcact aatttttgag ccttagcctt aaaacgctta gcattttgca
     2161 aataaactgc cttgtgagca ggatcttttt gactcaataa agctgcaatc tgctctgcct
     2221 cttgactagc taagatagga tcagtccaag tgtgaggatc atacaaggca tcggtattca
     2281 ttcctttttt tatggtgaag tgctccaagc cttgaacctt gtctaatgtt agatgtgatg
     2341 tcccctccat gactgctaat cccttttttt ccagctgtgg tgccaaatcc gcagcccaag
     2401 cttctaatat cttggaatgg taaataaaga catctccatc gtaaacctta gcaacaactg
     2461 tcggacttgg ctcatacgag tgtatgctag tgttttgggc aatgacctga acatcattta
     2521 aatccccgca aatctccttt gtcatagcat aaataggata aaagcttgtt tttatgacca
     2581 aaccggcctt cctactgcta gagctctgat gacaggctga tagacccaaa agtactgcta
     2641 atagtcctac tgcgacaatt gttttcttga atcctctaat catatctact ctcttaacta
     2701 gttaatgacc taaaaaggat accatgattt aactgaaatg tcaatatttt atcattttag
     2761 cgcacgacgt acacgcatga agaaaatgca tgtaagcctt ttttagcccc atgcattttt
     2821 taatctattt ctagcgtttt gacattgcaa tatcatcagt ttgtcaattt caatgtgatg
     2881 acttcatcac attttgctaa aaaggccata gtgatgataa aaaaccgcta ccagaaagcg
     2941 taaatgtctt cttgcttttg tcgtgatttt agtgaaccgc ctaccaactg aactgatgct
     3001 ggcttaacca tttcctggcc accatcaaaa gcctgcctct caattaacaa gcttactcaa
     3061 ggaagaggtg actgagccat gcatccgtct tagttatgac taacagctta tcttggcatt
     3121 tcattcatgt aattccagtg gcaggccatc aggatcaaaa aagaaggtca tcttcttacc
     3181 agtataatca tcatacctaa gaggctcgac agcaatgccc ttagccatta attgttcaat
     3241 ataagcttca ataggcttaa catgaaaagc taaatgacga agcccacagg cctctttgtc
     3301 atattcgggc ctaccgatac gcttaggcgg tgcctgataa gctggatcag tctttttatt
     3361 gccaaaaatc tctaattcaa tggctccaca ttttaaatcc aatttgtaat catgtctatc
     3421 aggccggtga ttttcacgaa taatctcaaa gccaagctta ttgacataaa aatccttaga
     3481 gacctcataa tccgaaacaa tgatagcaat atgatgaata gccttaagct ccatatgatt
     3541 tagttccttt attaaataaa aaaagtgaaa caaagcaatg ccaagattac tttgtttcac
     3601 ccctcgtagc gacccctcgc ctagattagg cttaggttga catctgattg taagagtgat
     3661 taaaggcctt caaaacatcg tcaggtgctt tgttaaactc atactcgttt ttgattgctc
     3721 ctttgacaat gattcgctct gttgcctcat aatccgtaca ggtgaccaag gttacctcct
     3781 ttagccctgg tgtgtcattg ataacatcta ttctctcagg tgtgaccgta aagacggcat
     3841 tgatctcgta ctcgtaaata cgctccttat ctgtaaggta aatagacatc ccttcttttg
     3901 ctctttcaag cggtgagaat aacatttcag aagagcctgt tagtccaaaa atatgatgac
     3961 tggctaagga gtaattgttt tctcctccca taacctggtc ctctttcatg gtaccagcac
     4021 cgtatataag ctctgtgttg ccaagccctt taaagattgg taggttaata ccaagctctg
     4081 gtatggcaat acctcctatt actggaagct gctgggcgtc catttgagcc tgtaagacac
     4141 tttcggtgct aactggctga actgcttgaa aatcaaagct tgactttgct tccttattct
     4201 ttttaatcgt cttttttgaa acctttgtaa cttgatattt attagaattc caagcaatca
     4261 gggtgtttct aatgggcttg ttaaataaca aggctaagcc tatgattaac aataagacga
     4321 ctagaatacc tctagcaaag gacatctttc ttcgtttttg tcttctcctg tgggttcttt
     4381 ttgccattca tttactcctt gctagaattt attggtgctt ctgttaaagc tgtatcagtc
     4441 tgagcgattg ctgttggatc gttgtcttca gcctgtacca aggtaaaggt aacaatctta
     4501 gaatctgtat ctagcctcat aaccttaaca ccaagtgttg aacggccagt ctgagaaata
     4561 cttgaaacat tggtacgaat aatcacaccc ttcgttgtga tcaccataat atcctcactg
     4621 ccatcaacag tcatcaggcc agccaactgg ccattttttg cggtgatatt agctgttttg
     4681 attccttttc cacctcgacc cttagttggg tattcggctg cactggtacg cttaccatag
     4741 ccattttcgg tgatgactaa gacctcttgc ttgtcattga tacgagaagc tccgacaacc
     4801 caatcttcct cacgaagctt gacaccacga acacccgtag cgctacgccc catgcctcga
     4861 atggtagctt cattaaagcg aacagaataa cctgatcttg ttccaatgat aatatcttcc
     4921 tgaccatttg tcaagagaac attaatcagc tcatctcctt ccttgagatt aagggctcgt
     4981 agaccattct gacgaatatt gctaaactct gatacctcag ttcgtttgac aatcccttgc
     5041 tttgttgtaa agaagaaata tttatcaaga atgtcttctt ttttagcatt gataattgtt
     5101 tgaatggttt caccatcatc tagctttagt agattgataa caggaagtcc ttttgcagca
     5161 cgtccatatt ctggaatctc ataggccttt aagcgataga cgcgcccaaa attggtaaag
     5221 aaaagcaatg tgtcatgtgt acttgttgag acaagctcac gaacaaagtc atcgtcattg
     5281 acacctgttc cctgtacacc acgaccacca cgcttttgag atcgaaactc gtcttgagca
     5341 aggcgcttaa tgtagccatt gtttgatagg gtgatcaaaa catcttcttc ctcgatcaaa
     5401 tcctcatctt ctaatgacaa tacctcacca atcatcaatt ctgtgcggcg aggattagcg
     5461 tacttgcgct tgatctcctc catttcttcc ttgatgatgg cttcgatacg ctctggcctt
     5521 gccaaaatat ctgccaaatc tgcaatcaaa gccagtaggt catcgtattc tgattgaatt
     5581 ttatcacgtt ccaagccggt caaacggcga agacgcatgt ctaaaatagc ctgactttgg
     5641 cgttcagaca agtcaaaacg agacatcaat tctgcttgtg cgataatatc tgtctcgcta
     5701 ttgcggataa tggcaataac ctcatctaga tggtcaagag cgataagtaa gccctctaaa
     5761 atgtgtgccc tagcttctgc cttgtccttg tcaaattgag tcctgcgtgt aatgacgtcc
     5821 ttttgatgta gaatataatt atcaataatc tgtctcagtg acaagatttt aggaatcccg
     5881 ccttcaatgg ctagcatatt gaagctaaag tttgtctgga gacttgtcaa tttgaatagg
     5941 ttatttaaaa tcacattagc agatgcatcg cgacggactt caatgacaaa tcgtacccct
     6001 tgtcggcttg attcgtcacg aacagctgta atgccctcaa tacgcttttc ttgggctaag
     6061 cgaacaatat gctcatggac ctttgtttta ttaatgccat aagggaattc tgtgacgaca
     6121 atccgctccc gtcctgtact agtggtttca atctcggtgc gtgaacgcaa aacgattgat
     6181 cccttaccag tctcataagc cttatgaatt cctgaacgtc ccatcaccaa ggcacctgta
     6241 ggaaaatccg gccctggaag aacctccatt aaatctctgg tagtgcagtc aggattttcc
     6301 atgaccatct taacagcgtc tatggcctca gctaaattat gaggtggaat attggtagcc
     6361 ataccaactg cgattccggt ggcaccattg accaataaat tggggaagcg agccggtaag
     6421 actaagggtt ctctttcatt accatcgtag ttatcctgaa agtcaacagt atttttatta
     6481 atatccttta agagctctag cgcgattttg ctcatacgag cctcagtata acgctgagcc
     6541 gcagcaccgt caccgtccat agaaccaaag tttccatgac catcgacaag catgtgacga
     6601 tagctccacc actgggccat acggaccatc gcttcataga tggacgaatc cccatgtggg
     6661 tggtacttac ccatgacatc accggtaata cgagcagatt ttttatgtgg cttatcaggt
     6721 gtgacgccta gctcattcat gccataaagg atacgacgat gaacaggctt taagccatct
     6781 cgtacatctg gaagtgctct tgctacaata acgctcatag cataatcaat gaaactcgtt
     6841 ttcatctcac ttgtcagatt gacgtcaact aaatgtttat cttgcattta aggaatgctc
     6901 cttttctagt caatactctt ttaattatac cataaaatcc ttattttttc tgattggaaa
     6961 cgctgtccga aaacaatttt cataatttgg tcgaatatca tgacaaagac attaaaatgt
     7021 gttaaaataa gatcgtatga gcaatttgct ctaactaaaa tgaaggagat gtttagaaat
     7081 gactgcaact aaacaacata aaaaagtcat cttggttggc gatggtgctg taggctcttc
     7141 ttatgccttt gcactagtaa cccaaaatat tgcccaagag cttggtatta ttgatatttt
     7201 taaagaaaaa actcaaggag atgctgagga tttaagccat gcgcttgcct ttacctcccc
     7261 taaaaagatc tatgctgctg attatgctga ctgtcacgat gctgacctag ttgttttaac
     7321 agctggcgct cctcaaaagc caggtgagac tcgtcttgac cttgttgaga aaaatctacg
     7381 tattaataaa gaagtggtta ctcaaattgt ggcctcaggc tttaagggaa ttttccttgt
     7441 tgctgctaat ccggtggata ttttgaccta ttcaacctgg aaattctcag gtttccctaa
     7501 ggaacgcgtt atcggttctg gaacatcact tgactcagca cgcttccgtc aggcacttgc
     7561 tgccaaaatt ggtgtagacg cacgttctgt tcatgcctac atcatgggtg agcatggaga
     7621 ttcagaattt gctgtttggt cacatgctaa tgttgcaggg gttggattgt acgactggct
     7681 tcaagctaat cgtgacgttg atgaacaagg cttggtagac ctctttatct ctgtacgtga
     7741 cgcagcttac tctatcatca ataaaaaggg tgctaccttc tatggtattg cagtcgccct
     7801 agcacgtatt acaaaagcta tccttgatga tgaaaatgca gttcttccac tttctgtttt
     7861 ccaagaaggc caatacgaag gcgttgagga ttgctatatc ggtcagcctg ctattgttgg
     7921 tgcctatggt attgttcgtc cagtcaatat cccattgaat gacgctgagc ttcaaaaaat
     7981 gcaagcttca gcaaaccaat tgaagactat tatcgacgaa gccttctcta aagaagagtt
     8041 tgcgtctgct gctaaaaact aattaaaaaa tgaatgtgtt agatcttgct ctaacgtttt
     8101 ggaatcacta caaaaagcct aatccaatcg gataggcttt tttcatgcgt ctaacagcga
     8161 ggtgcaagac aaagcacgct ttcattaagc atcgtgtgtg ctatgcttat agtcttaagt
     8221 cacaaaaaag acaaccagct ttatgagctg gctgcttatt agcttgttat tcagcaccaa
     8281 gtgctgccat tgtaatgtag ttatatggct tgttaaagtg cggtaagaag aaaatatcag
     8341 tcaaagctaa tttctcaatg gtcactcctt cttggatagc aagtgagaac atatgaattc
     8401 ccattgaaat atcttcatgt gaggccattt gagcacctag aatacgacgt gattctttat
     8461 cgtagacaat cttaatggtt acttggaagt taccatgctc gataaattct ggtttttgat
     8521 tgtcagtgta ttctgttact gctgcatcaa agccaaggca ttttgctttc tcaagagtta
     8581 agccagttga taccatgtgc aagccgtaga tagagatacc atttgatccc tgcacaccaa
     8641 taccctcaag agctgtgcca caagcgttat gagctgcgac aatccctgta cgaacagcat
     8701 ttgaagcaag ggcaatataa ttggtatcgc gagttgcgtt gtcatagatg gttgcacaat
     8761 caccgattgc ataaatccct ggaatagatg tttcttggtg tttgttaaca aggaaggcac
     8821 cattacggaa aagctcaatc ttgccagcac caagagctgt atttggacgg aagccaactg
     8881 caaggataac catatcaaca ccatattcat tcttatcagt gattagcttt tcaaccttgc
     8941 catcaccagc aacctctttg acagtttccc caaaggccaa ctgaatacca tgctcttcta
     9001 ggtttttaga catgacatct gtcaaatcac gatcatagta gcctgctaga caagtatccg
     9061 caacatcaat cagaataacc tctttgccct tacgttggaa ggcttctgca agctctacac
     9121 caatgtagcc tgcaccaacg actgcaacgc gcttaatgtc tttgttttct aatttcgaaa
     9181 tgacatctgc tgaattttgg tacaatttaa cgaattgaag attttcaagt gttgcttcaa
     9241 actctaatga gccctctttg atttctgcac ctttaattgg tggcaagata ggctgtgaac
     9301 cagttgcaaa aattaatttg tcatatgact caacatgctc tttgccatca acaagggctg
     9361 tcactgtttt agcatcgtag tcaatagatt gaactggtga ttccatgtaa accttagcac
     9421 caagggactc tagctcttcc ttatttgagt agaataagcc ctctgggcca gaaatttgtt
     9481 cgccaatcca aagtgccata ccacagccta agaatgaaat atttgagttt tggtcaaata
     9541 caacaatctc attagcatca ccatagtttg ttaacatagt cttgatacat gccgtacctg
     9601 cgtggtttgc accgataaca acgattttac tcatatgatt atgttcctca tttcacaatt
     9661 tatattaggt ctctattata acacagggaa aaagcgcttc caactaaaat gctcattttt
     9721 cttgcttttt tataccgttt tttagtcaat aaataagaca gcctatcatt tgttgaaggg
     9781 tcgtacaaag accggtttgc ttcagttaag tcaagacgac attcttattc aactattttc
     9841 ccaaattcat tacatgatta agaccatttt ttgtcgttaa cttctaaaaa agactcataa
     9901 gctcaatcag gtaaagattg acatgtacct cttgagcata ataaatattg ccgccgttgc
     9961 aataaagctt tccaccagag aggagggcta aggggtggta ataaaaatag gtttttccag
    10021 tagtatttcc taggctgggt gcaacgacag ttctagaata gttagtggct agttcaattg
    10081 tatgctgacc gccattttta gcaacgtaat caatataggc ggttccaaaa ttgtaagctt
    10141 gaacagctgt ccaagggtct acgccggctt tttctgctaa agctaaattg tgagatagca
    10201 atctgacacc atactcaatg ctagattgac tatcggtgat cgaatccctt atgccagagc
    10261 tgctttcgct tgactgcata acgtcagctt ctcctccctt agtttccgtg tatatcatgg
    10321 ctagtaccag atcgacgtct gctttgttac cgttttctgc taaaatacgc tctactgttg
    10381 gcttgtattg taggactctg tgcacattct tatgaatggt aactgcttcg tacaggcaaa
    10441 aaatgaggac ggctaatcct aagatacgct ttaacactct aaacatttag ttatttttga
    10501 tatcctctat attttttatc aatatggaat aggttccgtt gtcattcaag ataaactcta
    10561 ctgactcagc atcttgataa actgcattag ggacaagaag ctcaattcca tttgacagcg
    10621 acagcttttg cgtctctagc ttttttagct gtctagaatg atcaatatca ctgacctgaa
    10681 ttggttcggg aatcatttcc ttgacctgat ccacaaaggt taaccttgca gtcaggttct
    10741 ggtcaaataa ttgatctgct agcttttctg gagatagagc tgtttcttct tctagatttt
    10801 tagccagtgc tactttcatc tttgattgaa aagcaaagtc atcttggtta aaattctcgg
    10861 caaccttttg agcggtctgc tcaagcattt gaatagattt tttgacagat tgctcaggtg
    10921 ttacctttag cagcttctca gaaaagtaat gagcaaagct tccattgtgc ttcatgcgtt
    10981 tttcgattaa gtagtaatag cctgtttgac ggttaatgac caaggcttca tcaggtgcct
    11041 gagtagggct tggcaaatta ttttgcgtga tcgtaatagg attttcatga tcgtctgata
    11101 gatgggcaaa atgctctttt agggcaatgc gtaaaaaggc cagataaggc actccttcct
    11161 tatcaaactg aataaaaacc aaatcgtttg tcttttgatg ttcagaagcg acaaattctt
    11221 ccttccaaag cttggcaatt gttactgatg tttccaaaag ctctgtaccg attgtggtaa
    11281 aaaaagcatg atcagcttct aattgcccac gtttagcgtc gtcagaaaaa accttggcta
    11341 attttttgcg aaaatactca tcaattcttg gtgttatagc tactaaagca tctgataaga
    11401 tcagctcggt atcgtttggt gtgaattggt ggatcacaat tccttttata taaatatcta
    11461 gcattgttag ttcttcttgt ataatgggaa ggcgtcagtc aatcggcgaa cctcataacg
    11521 gacctcttca aggatttcag gctgctggtg gttaaccaag gccttgataa ttaaatgagc
    11581 aatagtccta ctttcgtcta ctcccattcc acgactggta atggcagcgc agcctatgcg
    11641 aatgcctgat gttttaaagg gagatagggt ctcaaaagga atagcatttt tgttaagggt
    11701 aatattaacc tcatcaagca aggcttgagc aagcttgcca ttttcaatca ccttagtcac
    11761 atcaacaagg aaaagatggt tatctgtacc gcctgagatc agacgaaaac gatcatcctt
    11821 ggcaaaaacc tctgccattg ctgctgtatt tgctataaca gcccttgcat agtctgtaaa
    11881 ggcaggatca agcgcctcct taaacgcaac agccttcgct gctatgacat gctccaaagg
    11941 cccaccctgt agaccaggga aaatagctgc attcattttc cttgaaattg cttcatcatt
    12001 tgtcaaaagc aggccaccac gaggaccacg aagggtttta tgagtggttg aggtcacaat
    12061 atgagcataa ggtactggat tttgatgcag acctgctgca accaagcctg caatgtgtgc
    12121 catatccacc atcaaatagg atcccacctg gtctgcaata aaacgaaatt gctcaaaatc
    12181 aatctgccga gaataggctg aggcacctgc aacaatcaac ttaggctgaa cagccttagc
    12241 ttgctttagg atagctgcgt agtccagctt ttcagtttcc ttatcgacag tgtagccgac
    12301 aaattgatag gtttttccag aaaaattgac aggtgagcca tgtgtcaagt gacctccagc
    12361 tgccaaatcc ataccaagca cagtgtcacc agcattaatc agtgccatat aagcagcagc
    12421 attggcctga ctaccagaat gaggctgaac gttggcatag gctgcaccaa agagcttttt
    12481 ggcacgctca atagcaaggc tttcaacaat atcaacatac tctgtgccgc cataataacg
    12541 cttgcttgga tagccctcag cgtatttgtt ggtcaagaca gagccttgtg cttgcataac
    12601 agcctttgag accatatttt cagaagcaat tagctcaata ttatgctctt gcctgtcctc
    12661 ctcggcctga atagcctccc aaagctcctg atcatagtct ttgtagttct cgttgttaaa
    12721 catcattatt gtctcctcta taatagcttc ataaatcgta attgtgtctt atcatctaca
    12781 tagctcagct tacggtaaaa ggcatgtgcc tcggtcctgt gactagcaga attaagccga
    12841 ataaagctta ctttctcctg cttagccttc tcctctaaag cagctagtaa gcgacgaccg
    12901 atacctctac cttgatggtc cagcctcact gctaaggcca aaatattaaa gcctttttcc
    12961 gagtaaagcg actcgtagca ttcagcatgc agatagccta agagcagatt ggtcttagta
    13021 tcagcatagc ccagcaaata atgatgctta tcggatctta gtttttccaa ttggcttttt
    13081 gtcaattcaa gagaaacctt gtaccccaag gattgatcat taatgtcaca aatagcttga
    13141 caatctgttt gatctagtgg tcttagcata gccttacctc ctctaaaatg gcagctctgg
    13201 aaccttagct aataattgct ccttagtaat agcaccttgt cgtaaaatac tgaccttagg
    13261 tgacgataaa tccaaaatag tagaatcctt ccctgtcaaa taggcatcat cagcataacc
    13321 atcaaccttt ccatcaaatg ccttgacaat gtcattaaag cattttccac tctttgagcc
    13381 tgacaggtta gcagatggcc caatcaaggg acccgttgct ctgataattt tagctgtgag
    13441 agggtgactg ggtagtcgaa agccaactgt ttttagccca gaattaatcc aatagggtgt
    13501 ctgggcattg gcttttagga taatcgtaag tggaccaggt aaaaaagcct cgtacagctt
    13561 gttaagatag gcaggctgct gcttagaaaa agccaaaata ctctcaaaat cagccacatt
    13621 aaggttcata gccttgtcgc gaggcctttt tttgagacga taaacagcat taacagcctc
    13681 ttcatttaag gcctgagcaa aaagaccata aactgtctca gttggtaaaa taagagctcc
    13741 accagcctta attgtctcta tcaaatgtgt tatcatcaac aaccaccatt ctttctttac
    13801 ccagcatatc cttaagcact ctgatacgct tttgagggaa acgcttggat aagagccttt
    13861 ttaagccttc tccctgcttg tagcctattt caaaatagag cttaccactt gtcgtcagat
    13921 aagcactagc ttgttcgata atgcgtcggt aaatagaaaa gccattttct gcagcaaata
    13981 aggccaaatg cggctcagat tgataaacat tcaagccaac ctcgtcctta tcctcatagg
    14041 caatataggg agggttagaa acaatgatgt caaactgccc tgatagcttg ctaaaaaggt
    14101 ctgactgctc aaaggctatc tctacatgat gatctaaagc gtttgagtaa gcaaggctca
    14161 aggcatcagc tgaaatatca gaggctgtga cctgccagtt aggtcttgct ttttttaaag
    14221 caattgcaat agcaccactg cctgttccaa tgtctaaaac ggatttgcga gtagcgtcat
    14281 tttccttcaa gataagctca actaattctt ccgtctctgg tcttgggatt agcacgcgcg
    14341 aatccactgc aagcaccaga tctctaaaat aagccctgcc tgtgatatat tgtggcgata
    14401 catgctggct aagcgctaaa aaaatccgct ctaataaggc ttgatcctct gaagtgacct
    14461 cttgattttg atgaagcaaa aagtcaaggc ttgtccactg ctttaattct ttaaaaacat
    14521 aggcgaggtt ttcacgatcc tcacctatgt tttctagcct gtcttcgtag gctcttagtt
    14581 gcttagcata gttcattggt tatttagcga ttctaatttc tgagtttgat catatagcac
    14641 taaagcgtca acaatctcgt ctaactttcc agacaaaatg gtgtctaatt tttgcagggt
    14701 tagaccgata cggtgatctg tcacacgatt ttgtgggaaa ttataggtcc gaatccgttc
    14761 agaacgatca cccgtaccga tagttgattt acgctctgcg tcctgctcgt cctgtgcgat
    14821 ctgtgcaaaa tgatctgcta cacgtgcccg aataatcttc atagccttgt cacgattctt
    14881 ttgctgcgtt ctttcctctt gcatctcaac cttgatgttt gttgggagat ggacgatacg
    14941 aacagcggtt gccaccttgt tgacattttg tccgccagca ccagaagcat ggtaaatatc
    15001 aatacgaagg tcctttggat caatgtcgta ctcaacttct tctacctctg gcatgactaa
    15061 gacagtcgca gttgaagtat gcacgcgccc ttggctttct gttacaggaa cacgctgtac
    15121 gcgatgagca cctgattcgt attttagctt ggaataaaca gattgtcctg aaaccatagc
    15181 aacaacctct ttaatccctc caacaccatt ataggaagcc tccattacct caaagcgcca
    15241 gccttggctt tcggcaaatt tttggtacat ggctaagaga tcaccggcaa atagagcagc
    15301 ctcatcacca cctgcggcac cacgaatttc caagataata tttttatcat catttggatc
    15361 tttgggaagc agcaaaagct ttaacttgtc ctcataggct tccttggcag acttggcctc
    15421 ttttagctcc tccttggcca tctcttcaat gtcaggatcg ccgccggctt ccttaatcat
    15481 ctcctcagcg tcatcaatgg attggataat agccttatac tgacgataag ctgctactgt
    15541 ttctcgtgtg ctagcctctt cctttgacag agccataaaa cgtttggtgt cagaaacaac
    15601 ctccggatca cttaataatt cgcctaattc ttcataacgg tcctcaacag cctgtaattg
    15661 atcataaata ttcattaggg ggtattctct cctcttttta cttgttttag ttgttattag
    15721 attggtgggt gaaaataatg cttgcgacaa actggaatat aggtctcatt gccaccaatt
    15781 tgaatctgtg ctccctcata aacgggctta ccatgttctg ttcgcaatac catagttgct
    15841 tttttgctgc aatattgaca gatggttttt atctcatcaa tcttatcagc taacagtaac
    15901 aggtatttgg agccttcaaa caattcattt tgaaaatcat tttttaagcc aaaggccatc
    15961 actggaacat ttagctcatc aaccacacgt gctaaatcat agacattttg cttgcttaaa
    16021 aattgacatt cgtcaatcaa gacgcaatag ggcttctcct gcaattcagc aataaatgca
    16081 aaaatatcca tatcattcga aattggtaca gcctcacgac gcatgccaat ccgactagaa
    16141 acaatgccaa agccatcacg tgtgtctagc gcacttgtca taatcacaac aggcttcccc
    16201 tgttcttcat aattgtgtgc taccttcaag atttcaatgg tctttcctga attcattgtt
    16261 ccatatttgt aatataattg agccaaaatg gagattccta ccttcttctt ttgtcctact
    16321 tattctatca tatttgtccc tatttggcga ttgccttatc tgaaaatctt attttcacaa
    16381 cagctaaatc ctgtgctgtt gagctaaggt taggcttttt gaagctgaca tgctacaata
    16441 gaggtatcat taaaaaaagg agattgacta ttatgccatt tgtaacgatt gacctgtttg
    16501 aggggcgtag ccaagaacaa aaaattgccc tagcgcgtga ggtgacagag gttgtttctc
    16561 gtatcgcaca ggctccaaaa gaagcgattc atgttgtaat caatgacatg cctgagggga
    16621 cctatttccc gcatggtgag atgaaaacca aagcctaatg cctaagtccc acttatctag
    16681 gtgggctttt cctatttgaa aaggagggcc tgatgatagc tactgatcag atcaagatga
    16741 tgggaacaat cattgatatt tgcattgact catcaaaagc aaagcagcaa gcagctacta
    16801 tccgagagct actaaccctt tacaatcacc gtttttcggc cagtgacgac agctctgaat
    16861 taatggcaat caaccatatg gcaggtattc agccagtgcg tgtgcattca gatttgtttg
    16921 acttaatctc aatcggaaaa gagcatagct tggcttatcc aagcaacctt aatatcacac
    16981 ttggtccttt agtgcaaagc tggcgcatcg gcttttcaga cgctaagctt ccagatgaag
    17041 caactattga tcgcagacta agactaacca atcctaatca tatcatc
//
LOCUS       DARYUW010000044        16701 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYUW010000044 DARYUW010000000
VERSION     DARYUW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16701
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..902)
                     /locus_tag="TVW11_001433"
     CDS             complement(<1..902)
                     /locus_tag="TVW11_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1365525.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..2391)
                     /locus_tag="TVW11_001434"
     CDS             complement(895..2391)
                     /locus_tag="TVW11_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1365526.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLS
                     WISKNTSLKIEYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANE
                     ALSMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVV
                     LKHIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEAS
                     YDMVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRND
                     AEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRR
                     LQCGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNG
                     STQVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
     gene            complement(2375..2590)
                     /locus_tag="TVW11_001435"
     CDS             complement(2375..2590)
                     /locus_tag="TVW11_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365527.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            complement(2740..3399)
                     /locus_tag="TVW11_001436"
     CDS             complement(2740..3399)
                     /locus_tag="TVW11_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1365528.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            complement(3443..5353)
                     /locus_tag="TVW11_001437"
                     /pseudo
     CDS             complement(3443..5353)
                     /locus_tag="TVW11_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(5461..7226)
                     /locus_tag="TVW11_001438"
                     /pseudo
     CDS             complement(5461..7226)
                     /locus_tag="TVW11_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            complement(7736..14566)
                     /locus_tag="TVW11_001439"
                     /pseudo
     CDS             complement(7736..14566)
                     /locus_tag="TVW11_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(14738..16165)
                     /locus_tag="TVW11_001440"
     CDS             complement(14738..16165)
                     /locus_tag="TVW11_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1365529.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            complement(16184..16363)
                     /locus_tag="TVW11_001441"
     CDS             complement(16184..16363)
                     /locus_tag="TVW11_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1365530.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            complement(16447..>16701)
                     /locus_tag="TVW11_001442"
     CDS             complement(16447..>16701)
                     /locus_tag="TVW11_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1365531.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
BASE COUNT         4514 a         3676 c         2353 g         6158 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat tgttatattc aagtgtttga cttgttatat agttatcttt
     2041 aatcactttg tattcaattt ttagtgatgt attcttactt atccacgata aatttgcatt
     2101 taacagctct aaaatatcat cattggtttc ataacaagta atttttatgg cttcaatctt
     2161 atcagtatca ataattcttt gaataagagc tgccgtaagt attcctgaac ccgctcccgg
     2221 atcgagtata gaaatttctt ttgaaaatga tgataaatca aataatgatg ccatgaaaag
     2281 agctgtttct ttacttgtga aaaattgccc atttttcttg cgaatttctt ttggcatctg
     2341 tttaatatat ttatttgtag attcaattac ataatcaatt attttcatca tccaccaact
     2401 ccataatttc atttacacca cagttcaaac tatcacatat tctgacaatc acatcagtag
     2461 taatattctc actgttcttc attttataaa aagtactccg gctaacttct gctttttcca
     2521 ttagctcaga atttttcata tctaaatcta tcattttttt aaatagcttt ttataactta
     2581 ttttcgacac gattgtcctc ccatgcatat gattttgttt ttatcattat atcatattta
     2641 ttcacttttt tcactacaaa cttcctttta cacaaacaca cgacatttag atagacaaaa
     2701 aagagtcggt gcagtcctaa gaccacaccg accatatatt tatctctcag cttctttgct
     2761 tgcgtctctc ttttcttttg gtttttcctt atcttcagac tgatatttct tgatagctcc
     2821 aagaacagat tctttctttt cttcttgtcc tttcatttgt tcctttgcct ttaagagctt
     2881 tgaagaaagt atccttacat tgctatgctc cttgccatta tcatcaatgg aagttctgat
     2941 ttgtccaaag agctttacaa aatctccctg cttaaagtct tttggaatat cactcttttc
     3001 tccataagcg gagcaattat gataaacctt atttccctca tcatctttag atacaacaga
     3061 gaaatttgcc accttaaagg cttctccatt cttgttttct ctttcagcta catcaacctt
     3121 tcctacaata tttccaacga tattgataag attatctttc tcttcctgaa catagggcag
     3181 gtcttttatt tgcccctgtt ctcgtaaatc ttcaatcatg tagtcaaatt cctcatgcag
     3241 taaattcaga ctgtcattgt ccatataagc gtcatagagc ttgtccaaag cactttcatc
     3301 attgatacct ttctccacgc ttataatcgc ttttacaaag tccttgtggt tatcatttgc
     3361 catatcttct atttgatttc tcattgtttt gtaatccatg ttttttatct cctttcatag
     3421 taaaagggag gttaccctcc ccttatctta aaaattcctg ttcttttgta gtttgttttt
     3481 cttctgtttt actttcttcc tgataggctc ttatctgtcc taaaatagat ggcttatcct
     3541 ctgatttttg tgaactttct tctttgctat gaaaattatc ctccacatca tatgttgatt
     3601 caaaatagtc gctgtcctta aagtcattat cgtaacggtc agtaattccg tcattatcaa
     3661 ggtctttaga aagcggatca tagaagttac cttcgtcatc aatatcaagt cccgttgctg
     3721 ctttcaaatc ttctgaatcc acataaacca gatcttcaaa agaggatagc tcaatctcat
     3781 ttttcatatt tcttagagtt tcattctctc ctttgttctc atagtcaaag ctctcagttt
     3841 ttatagatat atcatcaata tactgtgtcc atatcttatc ctctaaatta agctcatatt
     3901 gaatgctgtg tctttcatcc ggcgtgttgg tataggcaat tcctatatgc tttaagtcag
     3961 gatatagagc atcaaactca tcgtagctat gattttcttc atattctctg ttacagaaat
     4021 caataattgc ccttttaaca tcttctacaa ggggattatc atttctcttt tcttccacat
     4081 cacccatatc aagtagctta tttagttcag ccaagcgaag caccttactc tttaattcat
     4141 cagctttttc aaacggcttt tttaattcct ctttggcatt ttcaagctgc tctttggtgc
     4201 ttatgagctt ttcttcaagc ctctttaatt tctcaggcat tttctcaaga gcgttatcaa
     4261 gtcttgtaat attaccgtca gcacttgtgc caagctctcc tgaatgcttt gcaacaccgt
     4321 ttaagctgaa attatgagaa ttagtaaaga agttataact tgcttccaag tccatatttc
     4381 tgtacttacc gattacctta ctttcattga ttttaacctt tgaaatagct tcaagcaatc
     4441 tttctcctgc taatttctta tcggtaatct ttgctcctgc gatagtaata gaagtaaact
     4501 tttcctctcc gtccgcttta ggctctacat cagatatatc tttcttgaca gcttctatga
     4561 gcttttcagt tcttgcgatt tcttcaggat agtttttcgc cactttatcc tctaatctgt
     4621 aacggttgga cttatagttt gcttcaagca ttttaagttt cgtaacctca ttatccaaat
     4681 ccatcttttc tttaatcttc ggatcacctg tggcaagggc tttaatttct gcatagttaa
     4741 gtgaactttc atccacatct tctgccactc tgacaggtgt tttacttgtc ataatctgag
     4801 aaatgaactt ctgcttattc tctattgtct gccacaaata cgcatcaaag gtgttctccg
     4861 taacataacg atagatattt acttccttgt tttcattgcc ctgtcttaca attctgcccg
     4921 cacgctgctc taaatcggca ggacgccaag gaacatccaa atcatgaagg gcaatcagtt
     4981 tgttttgtac attcgtgccg gctcccattt tctgagtaga accaagtaat atcctcacat
     5041 ctcctttacg cacctttgca aagagttcgt ccttttgttt atcggaattc gcttcgtgga
     5101 taaaggcgat ttcttctttt ggtattccca ttgctacaag tttttctcta atatcatcat
     5161 agatgttaaa ttctccatcg ccttttggtg tagacatatc agaaaatagt agctgtgttg
     5221 acttatcttc ttttgtctta tcccatatac taaagacatt tttcacacag acattgacct
     5281 tactgtcagg attgtcaggt agcagaggat taattaaacg ctgatctaag gcaagttttt
     5341 taccatcatt agtgtagggt aggatactag cgaggtagtc attgcgaccc cttttccatt
     5401 atccccccac cgaaccggac atgatacttt cgcatcatcc ggctctccag taatttcatt
     5461 tcataaacgt gtatttattg aaccattatg tattgcatgg tgacaatccc gacaagtcac
     5521 tagcattttt cgacgtcttg ctgacatgat ttctttccac tttggaacta atttcccatt
     5581 gtgtttgttc aagtctgcta attttctgat atgatgtacc tctatgttct cctcacttcc
     5641 acatagctca cacttatttg cgagtaatcg cttgataagc tctgttcgac caccataaac
     5701 ttgatacgga gcatcttcta ttacagcttt ctttttatgc caccccacgt tgcaactaga
     5761 ggaggtttat cttctcgaga cacaactacc tgtaaacacg gcaccgttcg gccattcgtg
     5821 ctagttgtgg tagtcttata tttagctaac attttattaa tggatgactc atgtttaaat
     5881 gctaatgttt taaggagtga tgtttccata taccaataga cttttgagaa ccatgacaaa
     5941 ttttgtgcca atatataata ttgaactagc cctctatatt cttgttggta agtttgaacg
     6001 atactaaagt catcatcatg caataagtta ttacgatgaa tagctttacc atttttcatg
     6061 tattggcggc atttgctttc aataactgat gcaggtacaa ataatgcgat aacaccattg
     6121 gcactctgtc tccctttgtt atcaatataa tcattgacac gttgtgcttt tatctcatat
     6181 cccagaaatt tagctgattc tccagtcgca tgggtaatca aagtcttttc ttgagaaagt
     6241 tccaaagata acttagtatt taaaaagtct ccaatttgct tctttatagc ctttgcctca
     6301 gcttttgaac ctgtaaagcc tagaataaag tcatccgcat accgaacata tcttaatctc
     6361 cgatagctgg tatcataagt atcaactgaa gggagatttc ttctctcaac aattaactga
     6421 tgagcttttt tataatctcc tttatcctga tagcatttaa ttcttctact caaacgatta
     6481 taggctgagt ttgctttctg ctttttacct cttgtatatt gaggtatcag ctcttcaccg
     6541 acccacttat caaattgatg taaatagata ttagctaata aaggactaat aactccacct
     6601 tgcggtgttc cactaatagt cttgtgaaac ttccaatcat caagatatcc tgcctcaagc
     6661 atatttttga taagcctaat aaaccgacca tcctgaattt gtctagacaa catagtgatt
     6721 aatacatcgt ggtcaatcgt gtcaaaataa ctagagatat ctccttctat gaaccaacgt
     6781 gtccctttcc aagtctgaat ttcttgtaaa gctgtatgac accctctttt tggtctaaaa
     6841 ccatgagaat gttcactaaa ttgtggctca taataggctt ctaatatcat gcgaatcact
     6901 tcctgaagaa gtttatcact ccatactggt attcccaaag gacggtgttt tccattcttt
     6961 ttaggaatgt actctctcct agctggtctc cagtaatagg tttcttgtct taattgttca
     7021 ataatcatat ctattttttg aatagacatt ccatcaatcg tttcctctgt aacacccttt
     7081 gtcattgctc cattattcgg gtataacttt gcataggcta tcagatagag ttcacgatta
     7141 aatagtaact tataaaccct ttcgagtggt ttatcttgtt ttccacgttc atgaatgacc
     7201 gttaaaatag ttttggctgt acgcatccca cgcacctaat cctttctaac taatcgaaat
     7261 tacctgtcac ccttcgccat gtacaaggat ttcccttgct cggactacta cggtgactcc
     7321 gttaccataa gggtcccccc tcttaggcaa tcctgctatt cgttaaaaat gtacgttcta
     7381 gtaaccctta ggttcctcac tcattccttt attcatactt atcgtatgct cttttactgt
     7441 agaaagttat tcgtccaaaa tcacaacaac gaatatacag taacatcggt ctcagttact
     7501 ttccgatggg cgatgctttg cacctagtca gaattgaggt tcaagcagtt tagccttaac
     7561 cataggttac ggaacttgcg gcacatcaaa gcgttgtaac tcactcctta tccgctttac
     7621 taacatgcta ttgtcccctt tgggtttccc cgctaggtta gttagttgtt cctattattt
     7681 actttcaata atatccctct gtgagggaga tacattttta cgcttaacag cgcacaattt
     7741 ttagcatatt atctttgtca ggctctacca ccctatttct cacatcatct gctctttcag
     7801 aaaggctctt tagaatttcc ttttgctcct cacttggcaa ggtcttaatt acttcataat
     7861 gtgcctcagg tgttggaaga tttaacatat ccgctgtttg aatgtcagcg acttccttaa
     7921 acatagacat tagttcaggc aagttataga acttggaaaa tcttgtcttt actctgtatc
     7981 ctgttccctc cggagaaagc tcaaaagcag actgcgtttc cccaaaagta gaagcccagc
     8041 tatcaaaatg ctccagatta tttttcttta agctctcata ctgaagataa cgctgcatag
     8101 tgtaaagctc agtcatggag tttgatacag gcgttcccgt tgcaaagaca atgccttttc
     8161 cgtttgtcat ttcatccata tagcgacact tcataaacat atcggaggac ttaaaggctt
     8221 cactttgacc gattcctgca acattacgca tttttgtata aagatagaga tttttgtagt
     8281 tgtgtgcttc atcaacaaag agcttatcaa ctcctaattc ctcaaaggta atgacatcat
     8341 ctttcttaaa atcgtcattt aatttctcaa gccttgtttc cagttttttc tttgtctttt
     8401 caagctgttt tactgtaaag ttctgatttc tgtcatgctt gtattcttct acatagttta
     8461 cgatttcatc aatctgatct tggatatgct tctcctgata ttccttagac ataggaattt
     8521 tttcaaactg cgtatgcccg ataacaacgg catcgtattc tcctgtggca attcgaccga
     8581 taaaacgctt acggttcttc ggctcaaaat ctttcttatc tgccaccatg atatttgccg
     8641 acggatatag ctgcataaac tcacgaccga tttgtcctgt taagtgattg ggtacaacaa
     8701 acaaggactt actacacatt ccaagtcttt tactttccat tgcggaagcc accatttcaa
     8761 aggtctttcc actgcccacc acatgagcaa gcagggtgtt gcctccataa agacttcttg
     8821 ctatggcatt tctctgatga ggtcttaaat ctattttagt attcattccc tcaaaggaaa
     8881 gattacttcc gtcatattct ctgtttcgga tagagttaaa acgctcatta tacagtttta
     8941 caagacggtt tcttctctcc tgatcattaa atatccagtt cttaaattct tcttttagta
     9001 gttcctgctt ttgccctgca agcatggttt cttttttatt tagtacagaa gttttagagc
     9061 cgtccggatt tacaatctgg tcaaatacct ttgtttcttt caggtttaag gcatcttcaa
     9121 tcagcttata ggcatttacc cttgatgtac cgtaagtcat ttcagcgagg tcatttcctc
     9181 tatccctact tttaccttct atattccact cacttgtcag gtttgaaaac ttaaccttaa
     9241 tatcccatct tgcatatccc ggagttttca gcgtttcaaa aataaatttt tcaatatctt
     9301 taatcggtat ccaagtcgca ccaagacgaa cacttatctc acttgcttca agctcctttg
     9361 gtagaacttt tgtaagctca gccttttggt attccaaacg attcatctca tagctaatca
     9421 gctctttttc tttaccatct tctgcatagc caagatgagg taactctctt tccgtctgtc
     9481 tgagctttga tagatagcta tctactatgg caatcttgtc cctgatattc ccacttaaat
     9541 attcatcctt tgttacatag ccgtatttgt aggaattact gccattggca caggcaaaag
     9601 gcaaatctcc atcttcgggg ttaaaggata gaggtctata aaagttttgt tcttccctaa
     9661 tatttaagta gatttcccct cgaagctcct caatcaaagt cggtctgtct tttcctgtaa
     9721 gaccttccat atagtcaaag tccacatatc ctttttcaga taccgataag acaagggctt
     9781 ctaaagaagt atccacatga tctatgactt tagcctttgt aatagttctt ttggagaaaa
     9841 tatctccctt tgccttaaag ttttcttcat caaggatttc aatggaggaa acaagcggga
     9901 agttgctatc ctcttttaaa gctcttgtat tgcttaaatt atttacaaag ccatgcttat
     9961 tagaaaaacg gtcatagact tcatttagtt tttcctgtga agccttgatt tcttcctcac
    10021 taaaaccttc tttctgcttg taaatcacat tttttaaggc agcattcagc tcaagataat
    10081 ccttgatttt ttctttgttt ttatcggtta cttccttttt gataaacagt gagttttctc
    10141 tgtaatagac ttcatcatca ataatggtat aggaaaagtt cttaacatca tccgttgcag
    10201 ggattgaagt gatttcatca tctaaaagct ctatttcttc atacttggca tcttttgaaa
    10261 ttctttctcc tgcaatctcg atacgatcct ttaatgaagc catatttagc tctgtgccta
    10321 aataagatat cggttcacaa gttagagttt ttccaaatct tccgcttact tcacgcattg
    10381 agccaagtac ctgttcagga tgatcaacaa agtatttgtt atatacaaga ccgttttcat
    10441 cttccgcaag gtgtatccaa tcttcatcac gctctaatac gctatctctt ttctttaaga
    10501 agataatatc tgaggttact tctgtgccgg cagtaccctt aaaggtgtca ttaggaagtc
    10561 tgatagctcc taaaaactct gctcttgctg caagatagcg tcttacactt tcatcctttt
    10621 tatccattgt tccacttgat gtaataaagg cgataacccc gccgtttcta accttatcaa
    10681 tggacttggc aaagaaatag tcatgaataa ggaagttatt acgattgtat tccctgtcat
    10741 ttactttgta ttctccaaag ggaacattgc cgattgcaac atcaaaaaag ttattggaaa
    10801 aagaagtttc ttcaagtcct ttaatctgta tatcactttc agggtataaa agttttccaa
    10861 tcctaccgct tatactgtca agctctacac cataaaactt tgacttgttc atttcatcag
    10921 gaagatttcc tataaagttt ccgatgccca ttgatggctc aaggatattt ccgctcttaa
    10981 atcccatatc ggaaagtgtc ttatatacgc cgtcaataac agttttcggt gtgtaaaagc
    11041 tcgttagggt agattctctt gcagcttcat attctgcctg agataagttt tcctttagaa
    11101 agctcctcgc ttctttccac tgtccgcctt tttcttcatc gaatacatca gcaagtccac
    11161 cccagcctac ataccttgct aaaacttcct gagctgtact gtcaaactct ctttgtccac
    11221 tttcgatgcg actcagcata gagatggctt caaggttatt atttagcctt tcacttggag
    11281 ataacttgtc aggtaatgtt tcttccgtaa tcttgaagtt atgagcttct gctttcttta
    11341 tttcactttc tttagcaata gtttcaggct ttttatatgt cagattttca aataccctct
    11401 caagatcgct ttcaagacga taaggaatta catctgagcc tgttatcata ccgccaagat
    11461 attcggtatt atccttaacc gttaccgtct ttagattatt tcccatatcg tcaaagcgtg
    11521 tgatggtata gtctttatcc ttgtatttaa tttcatctcc aacgataaac gcaggtcttt
    11581 cagggcttac ttgtcttaat aaatcttcat tatctgtaaa ggctacaata gggatttgat
    11641 ggtttccact tcttcccgga tcaagccata agtcatatct ttctgtgatt ttattttcag
    11701 caatttccct tacagtatat tcttcatgat taaaatagac ggtatcgccc tctttaactg
    11761 caaattcatc tgaaatactt ttcttttctt cgttaagctc tacttcttcc ttctccttca
    11821 gataatcaaa tagtgtttcc tgaacaggtg ttgcagctac tctttcttcc acttcttcag
    11881 atatttcaag ttcttcttta tcttcaaagc taagttctcc gttaaagact gattgaagtt
    11941 cctgttcatc catctgcttt gcaagttctg tatctttaag ctctctaaaa gtctttggaa
    12001 aatcctctaa aataagcctt tgagcattta attctttcaa ttcttcaaga ttgaaatatc
    12061 cccattcagg ttcaaatcct aacacaagtc caaaggcatc accgctttcc ctatcatatt
    12121 ccgtcatata ccaagtccag ttagaacgga aaggaataat atatgctgca tgaacctctt
    12181 tatccgctaa agctacatct tcctgtgcgt aaagctcagg cactctttca agcatttcat
    12241 cagtcattaa gttttcagga ttatctttag aataatattg tagctctttt gattcttcta
    12301 cctctgactt actttctatt ttcttttctt catacagatt tttagaaagc agctcctcta
    12361 tacgctttgc cacacttgac caagtaagaa aaacatcatt acaattattc ttctgtaatt
    12421 taagcccctt tgcatcatgc cattcatcac ttcccattgc ccccgatact gcatgacttc
    12481 taccacctat gccatattcg tcttttagga aattagcttt ttcctgcaag gtatgatttt
    12541 ctttgaaaaa ctttgtaatt cgctcttttc ctctatcgac gccacttcct cttgaaagac
    12601 tttcaaggac ttcatcttct gtaatgaagg actttacctt cggaagctct gttagattgg
    12661 tactatattc ctttcgtgac agctcaagtt cctgtaacct ctgacaaagg ctatctacct
    12721 tgtgatagtg aaaccttaat acatttctgt tttctttgta tccttctaaa aacctgctgt
    12781 attctttgat cgtttccttt aggtagtcgg gattttttaa tgcttcagac aatctttttg
    12841 tttcttccgg aaagcctctt ccacttgttt tcaatagttc aaaatatcct tgtccttctt
    12901 cgcttaaatc atgcattaga taccataagg actctgaaat cttatctctt tcataatcag
    12961 gagcctcaga aatctctaca tttgtagcaa actcaccatt atcaagaagc tcatttatcc
    13021 tctttgcagc atcgctccag cttaaaattt gcgtagtatc ttctcttgca gatgtcccgt
    13081 aggctaaatg aatgccttta tccgaatacc aggaagatac ttctctttca tcaatgtaaa
    13141 atccattacc gcctctaaat atatctttta ggtattctcc taattcttca ttactttttc
    13201 ctttagaaaa ctcagcgata acaggaagtc tacttccatc gtgatttcct ccgttaataa
    13261 ggacagtatc tatatccctc tgagttaatg gaatggtaag tctcatctgt ccatatgaat
    13321 tttcgggtaa agaaaaagaa gccttttcag cttctcttat ctctatctca gtattatctt
    13381 ttaaattttt aatacttcct tgattgtcat ttccttcaga gctgaaatca tcgccccata
    13441 ctgcggatcg ttctcgtcct ctatcttcca agctaccatc aatttcggct tctctgtcct
    13501 cataaagtct atcgcctgtt tctgaatatc catcaggtgt cctgttagct tcctctcctt
    13561 gtatagatcc actaacatct cgaagtggct ctgctcctcg ctctctgaaa ggtaatccag
    13621 cctcattact gcgtaggtcg gattcggata ctcccttatg aagtccgtct gttcctccaa
    13681 gctgtttagt gtattctccc tgattttctc tattatctcg tccgtactct ccatttcgga
    13741 gaactcgctc attttcattt ctttcctgat catctcgtcg aagtacatca ttatctcctt
    13801 tctcaatttt ttctttaatc ctattatatc ctgcttcttt tcctcttaaa acttcttttt
    13861 gaagctcaag ctctttgctt ttttgaatgg tttcatcaat aatctttcca ctaatatccg
    13921 atacgatttc accaagactc ataagggaaa tgctatcaag cattgcaaag ttttccttta
    13981 gaagctcatt atccatagga tagtctacat taaatcttga agctactgca taactcactg
    14041 agtccctcac aaacttggta aaagatattc tatcctcatc agctattcta agctcattca
    14101 taaggctgtc tatcttttca tcaccgtaga gtctacttaa agaaaagata ttttctaagg
    14161 tgctttcact ttcctcatag ccctcgtttt ttatcatttc ctttaagaca tccctatgag
    14221 cttctttatc aaatctccaa agattgacct cattgacatc cctatttctt gaaaccgtct
    14281 gacttatatc aaagatatat gccacttttt tgtatgtgcc gtagtcctct aaaatgggga
    14341 tacctttttg tcctctcata acagtacggt taaagcgttc cctccaatag tcgaacttgg
    14401 cacaggctgt cgcttcagaa tttctatcat aaatacttaa ctgacttcta aagtcatatc
    14461 tttgattgtt tccgacaacc tttaggagct tcaggtattc tgcttcactt tgcaaaatat
    14521 tttgttttac aagctccaaa atgttatgaa aatcatttat tcgcattttt acctccttct
    14581 ttttccaaac aaaaaaggcg gttagatttt actctaatca ccttttgatt ctgtgtattg
    14641 caacttgctg caacttaaat ttcctactac aaatcctcat tttatggtat tcatagcacc
    14701 ctcttattta taaaaatctt tgttttgcaa cttaatttta ttcattcagt tcccagtgtc
    14761 cgctattacc acttcctaca tacttcagat tatctatttc ctttatagct ctttcgatag
    14821 tctttacgct aactccagct tcatctgcaa tagcctttct tgtaatccta tcattgcttc
    14881 tcactttttc tttaataaac tctgcgagag ctatcttatc gtgagcgaca tcgtgagcga
    14941 caccctgagc gacatcgtga gcgacattgt cgcctccaac cttttgtgtc gctatcttct
    15001 ttagaggaat aatcgttctg aatatatctc cctcctcaaa tagcgggttt tgtcctgaat
    15061 aaagctgtgt gtatttgtag gtatttcgca ttcctgaacc aagttcatcc gcaagaccta
    15121 tttctctaaa aactttagat atagcaggat ttttaggaaa tggctcaaac ttctgtaaat
    15181 ctaaagctcc catcccatga gccaagttgc tgttttcaac tgtaatcctc tcatcgtcaa
    15241 taatcatctt tgcaggaaaa ccacttgaat aatctctatg agccagcgta ttggaaacta
    15301 tttctctgag tatcctgtct cttgcattga cattgacaat tccgtccaag acaaataaat
    15361 cattcaagtg cttttgtcca aattctatca gtctgtcata gctgtcaatc agatttgtta
    15421 tgacaacatc tctatcatca tatctatcct tattttcaac cctgaatata gcatcagttt
    15481 tgtgttgcgg aagaacggac ataatagagt tatcttttcc aaataacaaa atagcagcta
    15541 atgtgattcc ttcacgcttt gtttccggat ctgtcagtat caaattggca cttctaagaa
    15601 gctcctcatt actcatattt tcccaaacat gatttttatt tcggaaaaca gccattttct
    15661 tagctttatc aatgacagaa gcatcaagaa aatcaatatc aagattcgga tataccttat
    15721 taacaaaata gcttccttgt tttcttgcat atagcttata tacaagctct gaatgatctg
    15781 tgatattgat gtccccttca taagacctat cccaaattct tccgttatgt ctgcatacct
    15841 gataaccttc aggaactctt atataaataa cttgtttccc ctcaatttca aaagtttccg
    15901 gcagcaaata aagtggtgga tacatctttt gcggattgtt gattgccgta gtaaattcct
    15961 taatcacttt atctacttta tcttcactaa caccaacgat ctctctttta tcatttgcac
    16021 caagtaaaat atgtccgcca tttctattgt tgaaagagca tactgtatca aagacatctt
    16081 tggttaaagc gttcttggat tctttaaatt cgacatctat tttttctccg gcttgaatta
    16141 acttcttaat ttcatctatc gtcatctgtt tatttcacca cctttatttc ttaatgtttt
    16201 cttcgataaa aacattggaa ttttgaattt caactctatc tttattaact acaaaagtaa
    16261 catagtctcc attttctaaa ttcaaaagtt ccctaatcct ctttggaata gtaacctgtc
    16321 cttttgacat aactttagca gtatctataa atgtatcttt catgactaat ccctttcgcc
    16381 ctacttttcc tacaaaagat tatagcactt ttaagatatt ttttctactc tgaaattagt
    16441 gtcatcttac ttactataag ttgaaaccgc ttcttttatc tcattttcaa tcgcttctaa
    16501 aaattcttcc tttgaagatt tcccttgagc aatatcggat aattccattt cccattttgc
    16561 ggtagtttct gccgacttaa agttatcagc tacaatcgct acaaggctta ttcctttatg
    16621 tgtggctata aggtttttct tatctctttc tacaaatccc ttaaagatta agttttcaat
    16681 aatccctgcc cttgtgaact g
//
LOCUS       DARYUW010000045        15705 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYUW010000045 DARYUW010000000
VERSION     DARYUW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15705
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(461..2872)
                     /locus_tag="TVW11_001443"
     CDS             complement(461..2872)
                     /locus_tag="TVW11_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1365532.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVKEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2887..3810)
                     /locus_tag="TVW11_001444"
     CDS             complement(2887..3810)
                     /locus_tag="TVW11_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1365533.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4137..5684)
                     /locus_tag="TVW11_001445"
     CDS             complement(4137..5684)
                     /locus_tag="TVW11_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1365534.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6309..7190)
                     /locus_tag="TVW11_001446"
     CDS             complement(6309..7190)
                     /locus_tag="TVW11_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1365535.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7355..8356)
                     /locus_tag="TVW11_001447"
     CDS             complement(7355..8356)
                     /locus_tag="TVW11_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1365536.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8497..9669
                     /locus_tag="TVW11_001448"
     CDS             8497..9669
                     /locus_tag="TVW11_001448"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1365537.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9673..11157
                     /gene="galT"
                     /locus_tag="TVW11_001449"
     CDS             9673..11157
                     /gene="galT"
                     /locus_tag="TVW11_001449"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1365538.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11167..12177
                     /gene="galE"
                     /locus_tag="TVW11_001450"
     CDS             11167..12177
                     /gene="galE"
                     /locus_tag="TVW11_001450"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1365539.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12254..13297
                     /locus_tag="TVW11_001451"
     CDS             12254..13297
                     /locus_tag="TVW11_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1365540.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13598..13741
                     /locus_tag="TVW11_001452"
     CDS             13598..13741
                     /locus_tag="TVW11_001452"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1365541.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14355..14516
                     /locus_tag="TVW11_001453"
     CDS             14355..14516
                     /locus_tag="TVW11_001453"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1365542.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(15108..15446)
                     /locus_tag="TVW11_001454"
     CDS             complement(15108..15446)
                     /locus_tag="TVW11_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1365543.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(15436..>15705)
                     /locus_tag="TVW11_001455"
     CDS             complement(15436..>15705)
                     /locus_tag="TVW11_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1365544.1"
                     /translation="DRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERVVEEKDL
                     PIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
BASE COUNT         4549 a         3513 c         3099 g         4544 t
ORIGIN      
        1 tagttttgga catttagttt cttctttctt gcgaatgggt acaattgtac ggctgctaac
       61 ctttttccta acccttttag acaccaaaaa actcccctta tcgtttttag tgattgtttt
      121 tcactgtcca ctttaaaggg gaggtctagc tattaaaggc taggcggttt tgactggagg
      181 actattaggt gtgaggttaa ttggtaaaaa ctctttctgt gctgccctcc ttaggtcata
      241 tagactttct tggaaccaaa acccacatat agcctacaga gatccaatgc tttaaaagct
      301 atgaggtgct aagctgctga tcaagtcagc ttctctgact gttgctgcaa gcaaaagcct
      361 actaagcgat cttaggctgt gaggcgtaag aacaggtcat cataccaata gctttttggg
      421 gataagctgt gatttgtatg ccttagctat tttatagtgt ttatttgatt tgttgcaatg
      481 ttgtcacatc ataaagcatt aggtgtcctt tttggtcata gaatttgaca ccctctggca
      541 cgaaaataag atactccggt ttaatgcctg ctatttcagc taactgattg atctgacgtt
      601 caagagttgc ccgatctaaa ccataattag gaatatcgtc aaataaagac ttggtctgct
      661 ctatgccatc tgcggcagta tcttgcgctg acggttcctg gtctttggtt ggcttaatag
      721 tgctttcagc tgcgtctgag gtcttattgc ctaataattc ttgaaccttt tgccattcat
      781 catgagataa ctcatcttta gtaatggttc ttaaagagcg tccaccaact ctaggaatgc
      841 taaaggaatc attacgccaa acaaaggttc cttcagcaag aacgtcctta ggatcaaaaa
      901 tatagccatc tggagctgcg taccgacctg ccttgatagc tgcttggacc tcttcggcag
      961 agtgaataat ttgccagttt tccattgaag tacgttgatc agctggtgtg acattagcaa
     1021 tgactcctcc agcttcatca tgatttgggt tagaccaaac atcaggacga gtattagggt
     1081 gctgcatgac atatttgatg gtcgcaatct gatccttagt tagccatgaa taaggtacaa
     1141 catggatatg atcgatgtga ggaatgacaa aagatgtcca tgtatcatag gttgcattac
     1201 cagcatgcat cggtaggctg gatacctcta cagctagctt tggctgaacg cctgtatcaa
     1261 caatgtcata aatatagtgt tgcttatcct taagcatgag ctcttgctct gcaaaggcaa
     1321 tttgtgttag gtctaaatgc tcacgatcat agaaatactc tttgccatct tttgtcatca
     1381 tgtaaccaac cttaccgcca ttggttacct tgcgactgac atgcttagcg tcaaaggaca
     1441 tgtctttacc gtctgattga actaatgccc ttgcaatctc atctgcttga ccatgctcct
     1501 gcagccattg tgcaacctgg tcaagctcct cttgctctag ctcaccaaag cccatgtaat
     1561 ggaaatgctc ctcatgctta gctgtgatgc ctgccttatc aacagaggaa atagatgcct
     1621 tactaaagac ataatgatca ctcgtgtcat aaggcttgcc atctaagcct ttaccataag
     1681 ccttaatctg atggccaagg aattgatgtg taacctcttt tgcagtctgg tcttgagtag
     1741 ctggctttgg cttagctatt ggactgccct gcgtttgacc tgctaggtaa cgatcagcca
     1801 aggttatttc aagggctgac aattgctcac gaggaataat atggtagtga tctccatgag
     1861 gaataacata gccaaaggca ttggcaaggg tcacctgagt tggctcaaaa atgagaccat
     1921 cttccttgac gtgcctgtat ttcttatcca agccatgcaa ttgatccaac aattctccaa
     1981 aggttttatc tgcaaatgat aggcttggat ctcctactga cggcaaattc ccagctgggt
     2041 ggtgaatcgg gttaacagga atatcatatg gtctaggctg atctccttga cctggtaaag
     2101 gctgaccgcc aataacactt ggttttccgc cttgcttgtt attccaatag gcctgcgctg
     2161 ctactagctc acttggggat aagtcctttt taggaatata gtggaagtga ctgccatggg
     2221 gcactaaaaa ggcatctccc atgtctccaa taacatctgt cgggctaaag atatagccat
     2281 catcagttgt atagcgtcct tgacttcttg cttcgttaac agctgccacc tctgccttac
     2341 tcaagtgggc aaccttagcc aagccttttt ccttagcttc ctttgttccc ttttcaacct
     2401 gctcagcaat ttgctgcttg gtacgaatat ttttacgctt gcttcctggc tttagataaa
     2461 cataatactt gccatcaacc ttgataatat agccatctag aatctcgtta acaacatcag
     2521 actgtttaaa ctgataattg gggtccgtca ttaatagctc ttcactaaga atagcatcat
     2581 agggaacctt accattgtag aaatggaaat gatcaccatg tgaggttaca tagccttgat
     2641 ctgtgatttt aacaacgatt tgctctgcag agatcccctc ttctgcgctg atttgatcca
     2701 ttgttttttc tttggggagg gcttttttgc catcctttga atcaatatag gcaatgctat
     2761 tatctttaga tgaggaattt agagccttat gcattccaaa ctgatatgaa gcagcattag
     2821 tagccaataa aatggccaca gctgatccta aaacaatatg cttctttttc acgttttcat
     2881 ctccctttat tttaagcttt ggtaaagagc ttccaaatta gctctcaaat tgtctagata
     2941 ggacttgttg tttttgggcg ctgcctctag tggactgagc agcttgacct ttgctcctgc
     3001 tgttttagct atcgccttag caattttagg attaacatta tcctctgcaa aaatcgtttt
     3061 taccttatat tctttaacaa agtcttgaat ttcagttagt tggcgaggag taggctcttg
     3121 ctctggcgaa ataccagaaa tacctaactg ctttaagcca aagcgttttg ctagataaga
     3181 aaaggctgtg tgctgtgtga caaaggtttt agatgatgtc tttttaaact ttttagtgta
     3241 ctcatcagcc agctcttttg cttccttttg gaatgcttga gcattctcag tgtaaatggc
     3301 ctcatgctta ggatctaaac gactgagctc cttagcaata gcgagtgctt cttcacctgc
     3361 taaaatagga tctgtccagg tatgaggatc atacagggta gcagggtcaa tgccatctgt
     3421 cacctcaata tcctccaaac cagtaacacg atctaaggtt aaagatttgg aagcttcaaa
     3481 aacagcaacc tttgatttct tcaaattagg atccaaatca tcagcccagg cctctagggt
     3541 gtgagagtga taaacaaata aatcagcatc gtaaatggca gcaacgtcat ttacagatgg
     3601 ctcaaaggaa tgaatacctg cccctgactg aatcatccga acatcgttta gctcaccaga
     3661 taccgccttt gtcatggcgt aaataggata aaagctagtg acgatcgtca tgcctcttga
     3721 ctgcttgctt tgctccttgg gcttgctaca ggcaacaaga cctgaaaaaa gagcaagcaa
     3781 cagtgttaaa tgtatccatt ttcttttcat ataatctcct ttgctcatta accagttatg
     3841 aaccggttaa ttttaacagc tttagatgta tttgtcaaat tttttaataa aaaataaaag
     3901 ccattaaaac gatggcttaa tcagccccta acctgcttaa cctttataag aagccatagc
     3961 tctatgataa actgtggtct gtgacgcatg acctcactgt ctgttatctt actgttgcat
     4021 gatacgttta aaaaagattt agccttcttt ttttagattg tagaacggcg ctgaacaatc
     4081 acttaaccgt caaaaaaacg ccttgatagc tgcaagacgt ttttacttat ttggttttag
     4141 ctagagcgac gttttgtcac aagaccgatg acagctgcaa ggcctattaa tagaactccc
     4201 atgaacgcta ccatcggcgc tgctgattca ccagatcttg gcaaagcctt agtctctttt
     4261 ttaccttctt taggggctac attacggttt gacgaggact tggtttctgg cttagcgaca
     4321 ttcttatcct tttcaggatc ctttggctcc ttgcctaagg gctttgtgtc tttagaatgg
     4381 cgctcagact cgctgagttt attatcggtt ctgatttgag ctttggttaa aaagccgctg
     4441 acatcactac cggtagaggc ttttttaggt atcttgaccc cgttgataac aatctcataa
     4501 aacataccgt ccatgagctg attcacaaag gttgccttac ctgattgatc agttttgcct
     4561 attgccctga tagctccgta tcgatttttc agcacaacct cttgccctgc caacttattt
     4621 ccattggcat cataaacagt tactatggct ggtgtcttag agtaaacaac aggctttgtt
     4681 cctttaccgt cgacataaaa agcagcagcc ttatgctcat tagactcact cgtgcgaaca
     4741 gtatagccct gtagcttacc atcaattgag acactgatat tacgtgatag tggtagtttg
     4801 gtaaagactg cttgaccatc agcatttgtc tttgctgaag caattgtcgt cttagcaccg
     4861 tctatcagag cagtcaagct tacctccttg cctgcaacaa ccctatcctc tttatctagg
     4921 gcagtgacaa caaaatgaaa gccttcctct agcggacttg actttccatc ctcctgctta
     4981 ggagtgtcct tggactgagg tgacgtacct gatgacgagc ttgatgaggt atcaaggtaa
     5041 gcattaacag acatttttgt catgacctgc cctatatact taccattaag ctcataatga
     5101 taaaaggttc cgtccaacaa acgatccttg aaggttacct ttccattttt atctgagaca
     5161 agacttccca ccagttgacc ctgacgtatt tttagggtga ctgtttgccc ttctaagggc
     5221 tcactatctt gatttcggac cgtaatatca atgacatttt tactataaag aggctccttt
     5281 gtccctgctc ccttagcgac aaagcttgct gcctctttag atccagcaag actggttctc
     5341 actgtatagc ccttggtttc cccgtcaaca gaaacactca aattaatgtt taagggtaat
     5401 tgagtaaaaa tagcctgacc attgctgtta gagacagcag aagctacctg cttagcggga
     5461 ttagctgtcg tgtctaacaa gacaactgtt tttccttcaa gagcacgacc gttgctatca
     5521 agtatcgtgg caacaaaatc aaaaccctca gccgcttgcg acgtcgcagt gacaacgttg
     5581 tctctggcat aagtcgtata ggtattggca ttggctgcca aggccaagct agatataaca
     5641 gtaaccgtta aaagactgac ttttttcaat gactgtttct tcataaaaaa gctcctttat
     5701 tttgattaac tagcctagtt ttaatgggaa atatcccctt gatacccttt ctgaggtgat
     5761 aggaacagca gcaatctctc ttagcctatg atgcctaagc tttaaagcta agttttcaaa
     5821 gtccacctaa ggggctacat gccacaacaa aaagcatcag atgaacagac atctagaggc
     5881 aacagccgat ctaagataat agttagtagc cattttagct actctcaagg ctgtcgccgc
     5941 agtgatgatg tgattgtcta tgctttttaa taaaacttaa ctagttaaga tttttgtgct
     6001 gctatcctat caaataaccc ccgccaagtc aacaacaatg ctcataccac agcaagcaaa
     6061 gcattttgat gatgactgaa cagccaaatc agccaagccc caggcagcaa aaaagaggat
     6121 tcaaaccaaa tcctctctct actaagcctg ctgctgttaa cgtatcatgc taaaggcaaa
     6181 tggtatagcc acgctgatat gaaggtctga ttaacagcta cgacggacac gcttgttaag
     6241 gctaccattg ctaatcacac taggtcatat cctccaccgt ataagaatga ctaacttcat
     6301 tattcagatt aacgatatac ctgcaggtgc tgaggaagta ccttgacagt gattggtaag
     6361 gcctcaccct catcaccgtc cacattgata gatagctgtc cttccttcat ggcaatagtg
     6421 gcctccttga aggtttgata gccaagtgtt tgatctgaag cctcaactcc cttcaatagg
     6481 ctaggaaggg ccttcaccgt ttctaataga ttgctatcct tcagatagat aaggtgcagc
     6541 aaaccatcgt ccacacgtgc ctctggcaaa atccgctcaa agcccccgat tgaattggtc
     6601 aagccaatca agagtgttgt gctgttgatt tcttttgttt tgccatcaat atctagctgg
     6661 aaggtatagc ttttattttt gatcagctgc ttaaagcctg acataaaata agccattttc
     6721 ccaaaggtcg tcttctcctc aggggcaaca tcattgatcg cctctgggag cgtccctatg
     6781 gcaacaacat tcataaagta agcatcgttg accttaccaa tatccagagg actggttgtc
     6841 tcaaagctta tctgattaat cgcttcctct gggtctaacg acatgcccaa ggcacgtgcc
     6901 aaatcattga ctgttcctag aggaaaaaag ccaaacttag ggcgatagtc ctgctctgca
     6961 agcccgctga tcccttcatt gactgttcca tcacctccca tgacaaagac actgtccagc
     7021 cgctgctggg ctgcctcatg agcaaaccgt ttggcatctc ctcctttttc agtgtgctta
     7081 acgtcaacat catcaaaata cgaagctagt ttatcatagg ctaaggcttc atattccttg
     7141 gctttctcac cacctgagct agggttaaca atcaataggg cttttttcat ttatgatatc
     7201 ctacattttc tattatattt cacgactatt ataatcatta ttcaaaacat cgtcaaataa
     7261 tactcactat gtcattagtc agtcttaaag cttctaatat ggttgccgtc tagtgtttca
     7321 ttttactgaa ctctttaccc agctagctca atgcctaacc aatcgtgctg tctcttaagg
     7381 tcaactctgt cgccaatatc gtcatggtct tgacacgttc tgggttaagg atattcctat
     7441 taagcacatc aacagccata cgtcccatat cctctgtaaa tacagtcaca ctagaaagcg
     7501 caggaaagac ctgtcttgtt aaaggagtat cgttaaagga gataagctca acacgctcag
     7561 gcaccgcaag ccctctttct tggagagctc ttagagcacc tattgcaagg gtatcattag
     7621 caataaaaaa tgctttaggc aaatcatcac ctagctcctc aattgcctgt gtcataagct
     7681 catagccaga ttgtgctgaa aaaggaccga tatagacata cctcggctga taaatcccat
     7741 gctcagaggc ataattttta taggtgcgaa agcgctggtc cactaaagct tctctaccgt
     7801 cagttgtctt ttcctcacca gcaatcatgc caatgctata aatccctttg ctcataaaat
     7861 aatcaagaac tttcagcact gcattgtcaa agtcagttgt gacacagggg tggcccaatt
     7921 caagcgtgtc actatcaaca aacaccaaat gctgggataa ggcttcaagc tccttgattt
     7981 gacaagcgct aaactttcca atagcaataa tcccggcatg gtcatctgaa accctcaaaa
     8041 tgtcattgtt gaaataacga acaatatcat aatccaattc ataagctctt ttttcaatgc
     8101 caatgcggat cgcataatag tagaggtcat tgagctcctc ttcttgagaa taccattgaa
     8161 caatagctat ttttagcttt gatttagggc tattcgtcgc ttttaaatgc ttttggtagc
     8221 ccagctcatc agcaattgtg agaatgcggt gctttgtctc ttgaccaaca gacaagcttt
     8281 ggtccttatt taaaactcta gaaacagttg caggagaaac ctttgccaga gctgcaatat
     8341 ccttaagcgt taccatatca aaccttcttt ctgatttctt ctagtatatc acaagcattt
     8401 tcaaaagcaa tatttagtaa aattttagta aaaatgttga cgagcagctt agcgaagcgt
     8461 aaaatcaagc tatcaacatc gttaaaggag ccgctaatgg atatcgcgca acttaagcaa
     8521 agctttactg acgtttttgg caaggagcca gatgctgtct ttttctcacc gggtcgcatc
     8581 aacctcattg gtgagcacac tgattacaat ggtggacatg tctttccagc tgctatcagt
     8641 ctgggaacct atgggctggc ccgcaagcgt gaggatcagc agctgcgctt tttctcagca
     8701 aattttgaag aggctgggat tattgaggtt gacttaaatc agctgacctt tgatcaggct
     8761 gacctttggg ctaattaccc taagggagtt ctctcctttt tgcaaaaagc tgggcacctt
     8821 attgatacgg gctttgagct ttacgttttt ggcaacattc caaatgggtc tggtctgtcc
     8881 tcctcggcat cactggagct tttgacaggt attgtggcac aagagctgtt tgggcttgat
     8941 gtggaacggt tagatctgat taaaatcggt cagcaagctg aaaatcactt tatcggggtg
     9001 aattcaggta tcatggacca atttgccata ggcatgggag ctgataagca ggctctatac
     9061 cttgatacca acaccttagc ctatgaggct gttccgcttg accttggtga tcacgtgatt
     9121 gtcatcatga ataccaacaa gcgccgagag ctagccgatt caaagtataa tgaacgccga
     9181 gcagagtgtg aacaagccct tgaggaatta aatgcccttc tggatattaa agcactgggg
     9241 gaattagacg ctcagcgctt tgatgagtac agctacctta tcaaagatgg taaacgtctc
     9301 aaacgcgctc gccacgctgt tttggaaaat caacgaacac tccaagcaag acaggccctt
     9361 gaagcaggag cattggagca atttggtcgt ctgatgaatg cttctcatgt atccttggag
     9421 catgattatg aggtcacagg ccctgagctg gacacactgg tccacaccgc ttgggagcaa
     9481 gaaggggtcc taggggctcg catgacagga gcaggctttg gaggctgtgg cattgctatc
     9541 gtggctaagg ataaggtaga tagctttatc gaaacagttg gcaaggccta tactaaggtc
     9601 attggctatg ctccagcctt ttatctggct gagattgctc agggagcacg actactttca
     9661 aggaaataag atatggcaag cttaatagac acctttgtaa ggaaggtgat tgaacacagc
     9721 gactacacat cagaggacgc tatttatatc cgcaatcggg ttttagcatt ggttggtgag
     9781 aaccatgtct ggcaagaaac ctccttaaca gccttaatag ctctcaaaga agcattggtt
     9841 gagctagctg ctgaaaatgg caaaataggc aggcttcctg aagaaaagga ctgcttagga
     9901 gctgaattaa tgaacatgat aacccctatt ccaagtgtgg ttaatcgtcg cttctgggat
     9961 acctatgcac aatctcctca acaggctatc tcagattttt accagcttag tcagctaaat
    10021 gactacatca aaacagcagc aattgccaaa aacatctcct ttacagtgcc ttctcaatat
    10081 ggtgatatgg ctattaccat taacctatca aagcctgaaa aggaccctaa ggccattgca
    10141 gccgctaaga aggctaaggc atcctcttat ccaaaatgcc agctttgtat ggaaaacgaa
    10201 ggttatcaag gacggattaa ccacccagcc cgagctaatc atcgcattat ccgtatgagc
    10261 ttaggcaatg aggcttgggg attccagtat tcaccctacg cttattttaa tgagcacagt
    10321 attattttta atactgagca tgtgccaatg acaatcagta caagcacctt tagacagctc
    10381 cttgatattg ttgatatcct gccagactat tttgtcggct ctaatgctga tctgcctatt
    10441 gttggcggct ctattttgac ccacaaccat tatcaggccg gtcggcacgt ttttccgatg
    10501 gaaatcgcaa aacaagacaa acgctttacc tttaaaggat ttccagacat acaggctgcc
    10561 actctcaact ggcctatgtc agttatccga ctgcgcagca gcaacaaaga tcagctagtt
    10621 caattagcag acacgattcg actggcttgg cgtcattatt ctgacgacag tgttgatatc
    10681 gtcgcttata ccaaccaaga gcctcaccat accatcacac ctattgccag aaaaaaagaa
    10741 gggcagtttg aattagactt ggttctacgt gataaccata cctctgagca atttccagac
    10801 ggtgtttacc acccacatgc cgatgtgcaa cacattaaga aagaaaacat cggccttatt
    10861 gaggttatgg ggctagctat tttaccaccg cgcctcaaag aggaattggt tgaggtcaaa
    10921 aaatatatcc tcaatcaagc caatcaaatc gcagactacc acaaggactg ggctgatcag
    10981 atcacattac gaccagatct ctcagcgata actgttgatg acattatcca agaagaggtc
    11041 ggctctgtct ttgttcgtgt ccttgaggac gctggcgtct acaaacgtga tcaagaaggt
    11101 caagcagcct ttatgcgttt tcttaagagc attggcattg aagcaattga agaataggag
    11161 gaaaaaatga ctgttctagt tttaggcggt gcaggctaca ttggatcaca tacagtggac
    11221 tggctaatat cacagagaga agaaaaagtc attgttgttg atagcttggt gacagggcac
    11281 cgtaaagccg ttcacccaga ggctctgttt tacaaaggag acttagcaga caaagccttt
    11341 atgcgtcaag tctttaggga caatccagac atagacactg tgattcactt tgctgcctct
    11401 tccttggtcg cagaatcaat ggcagaccct ctgaaatact ttgacaataa cacagcaggt
    11461 atgattaagc tgcttgaggt catgagagaa gccaaggtta agcgcattgt cttttcatca
    11521 acagcagccg tctatggcat tccaaaaaca gtccccatct tagagtcagc gcctaaatgc
    11581 ccaatcaatc cttatggcca aagcaagctt atgatggaaa cgataatgac ctgggccgac
    11641 aaagcctatg gcatcacatt tgtggccctt cgctacttca atgttgccgg agcaaagcca
    11701 gatggctcca tcggtgaaga ccacgagcca gaaacacatt tattacccat tatcctacag
    11761 actgcacagg gagtgcgtga gcaggtgatg atttttggtg atgattatga cacaccagat
    11821 ggtactaacg ttcgagatta cgtccatcct atcgatttag ctgatgcaca cattttagcg
    11881 atggcatacc tgcgtcaggg caaaccatca caggtcttta atctagggtc tcaaacaggc
    11941 ttttccaatc gtcaactgct tgaagccgct cgtcgggtaa caggacaagc cataccagcc
    12001 aaaaaagctg caagacgtcc cggtgatcca gacaccttaa ttgcgtcatc agaaaaagca
    12061 cgcaaggttc tcaattggaa gccaagctat gacgatattg acaagataat cgcatcagcc
    12121 tgggcctggc ataccaagca tccaaaagga tatgacgata aagcaagtgg cagctagtcc
    12181 ctcaagacag ctaccacagc aagtagtcag cctcccttaa ttcatacacc tatactaata
    12241 ggagaaacaa actgtgaaca tttatcaaga catcattgaa tacatcgatc aagtgccagt
    12301 cacccagcta agactgatta atactaacgg tgttgaggct cacctattga cactaggagc
    12361 cactctacag gcctttctag tgtcaaatga aaagcagcca aaaaatatca ttttgggaca
    12421 tgaccgacca agtgactacc taaaaaatcc tctttgtgca gggcaaacca ttggccgagt
    12481 agcaggtcgc ataaagagag gaagctttca gctagagcag caaagggttt gtgttgacac
    12541 caatgaaaat gggcattgcc tgcatggagg cttcaagggc tttcataagc ttcattggcc
    12601 ttatgatacc cgccaaacag ttgattacct tgaagtaacc tttaaaaggg atattttaga
    12661 agcagatgac catttcccag gtgacctgac cgtaagcatt acctaccgtc tagacaacca
    12721 taatcgttta agcattcact ttaaggctca tagcatgaga ggcactagcc tattcaatcc
    12781 aaccaaccat gtttatttta atttagggca aacacaagac ttaaccaatc acaacctata
    12841 catcgcagca tcacatagga ttgaaacaga taatgagcta atcccaacag gtcaaaagct
    12901 agcagttgac cagacggtct atgattttag atcaataaag tccctctatc ctgctattgt
    12961 cgaaaataat ggctttgata ctgcctttga aattgatcag caggctattg gaacaaccaa
    13021 acctattgct gtcttacaag acagcgtcag ccatgaccaa atcagcatct actctgaccg
    13081 aaacgcactc gtcatttata ccatggacag tatccaagat ggcttgtatt ttggaagaga
    13141 tcagggcaag gagggactgg ctcgtgaggg gatcgctatg gaagcacaaa ccctgcctga
    13201 tgctattcac cacaaccagt ttggtgacat tatcctcaaa gaaggaggca ccaaaagcta
    13261 cactatctgc ctagcctatg agcatctgcc agattaacat aagtacagcc aagctttaat
    13321 gaaataacaa gaccttgatt tttttgaatt gcaccccaac cgttagccaa aaactctaac
    13381 aagcgaggat cagttcattc atcaaggtct tttcctcttt ttatctatag gcgttacaaa
    13441 gtagatatag gaacatcata ccaaatatgt ggaatgctaa gagcttatca tcacaaagcg
    13501 aatacatgtt ccgactacat ctatgcatta gtaagtcttt ttcctaaacg aagtgttgcc
    13561 agctttatga gatacttaaa agtataagag cagcctaatc atttttgaca aagacaccaa
    13621 ccttaagcat aaacataggc atcagaaatt ttggtatatg ggctattatg gagacacagc
    13681 tggtaaaaat ctaaaaacga tagccaaata tatttcaaat cactatagga agatagggta
    13741 gcaaaccaac tgacatcatt tgagaccatt gatccattta caggccaacc aaataagaaa
    13801 aagtaacctt ttgattgaac tcccgctcgg aaaagtggag cgcgagtatt caatgacctc
    13861 gttatcctcg accgatgaga gcagcttata gtcacagtat aaagaggctg gaacagacaa
    13921 cctcttttga ttgacaataa gtgtttgata gcattgtatg ggattacttt cacatcattc
    13981 agcacctggg tcgagctttg atgaccgcca gaattgatag ccattatgaa gggctttgag
    14041 cagccatttc tgctttatcg aaccataaaa tatcattgat gactgctcca aaaggacagt
    14101 cataaactgt ctgatcagcg cttctagtca cgaaccttta agcaaacctt aatactcaaa
    14161 aaaggtaagt cagaaaatac ttgatttctc agatgagctg tggaattacc acgaccttta
    14221 ccagctcttg ctctttcatt ttcaaaaagt gggtaaccga gtttttcggg ctgattgaag
    14281 agctttaagc ttggtcaatc atcacgtttt aaccgtcctc aaaatctttt tgaaatacaa
    14341 accctacatc acaaatgcct tattccaatg ctaaattgga gcccactaac aagactatta
    14401 aggacatgaa agagcaagcc tttggattta ggaactttaa gaacttcaaa gtcaagattc
    14461 ccaatgcttt aaacatcaca aaagaagaga caaaatttat ctcttctcgt gcttagctat
    14521 cagtcaccca ctgcagttga cattgagcca aattatagag ccattttcgt agaaagcaca
    14581 gaaaaaacac ccatgaggta aactcttgag tgctttgaaa cgttgatata atgcgatata
    14641 ttaacgtttt gaggcacgga gactgcgtct cctttgcagc cgtattcgta agcgactaaa
    14701 gccgcaacga ctacgtcaat tgcgtcgcca gttctttcaa aaaagaaaat accccatggt
    14761 aacccatgaa gtattgttct gctgtattgt agctggttct taacgttttg agaactgact
    14821 agctttacga gctttcttaa gacctggttt tgggtgacaa aaaccaaata tctgtaaaag
    14881 cttatcaaat caagctttca aaactcattt tcattaaata taagcacttt taacccaatc
    14941 ctacaaataa tagattacca ttagattacc aaaactcagt tttcggagct tatgtagttg
    15001 agaaaatctc gtatttactt tgcttttata tatccacttt atactatcat cccgtcataa
    15061 cagagcatga ttaaatagtt acataaaaaa caatacttac tctatcatta aaggatattg
    15121 ttaaaaagat tctctaaatc atttaaataa tcagttttag tacttctaat acgaagaata
    15181 tctacccttg actgacgaat taaataaaat actatgaaat gcttactagg aatcatcctt
    15241 agctggcctt caggaaatag tttacgtcct acacgatcgt caaaatcaac ataaccttca
    15301 ggggatatct caagaataga aatagctgac tgcaaagatt caataacttt ttgagcgctt
    15361 gagtgcgaaa attctgttaa atagtagtta tagatttcat ctaaatcttg ttctgcctta
    15421 tttgaaatat agatatcata agccatattt tgaaaatacc tcattagctg gcttcgtacg
    15481 tcctgctaaa atatcttgat acccttcatc aagctctgat atcagttcat ttaaaaatga
    15541 ttcagctcta atttgttctg cagttttaat aggtaaatct ttttcttcca ccacccgttc
    15601 aacaaataga ttaagagcat ctggaacact aatattttta gcttctaaaa tacgctttgc
    15661 ttcttccatc atttccgtat ttactctaaa attatactgt ctatc
//
LOCUS       DARYUW010000046        15640 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYUW010000046 DARYUW010000000
VERSION     DARYUW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15640
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..1034)
                     /locus_tag="TVW11_001456"
     CDS             complement(<1..1034)
                     /locus_tag="TVW11_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365545.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1040..1894)
                     /locus_tag="TVW11_001457"
     CDS             complement(1040..1894)
                     /locus_tag="TVW11_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365546.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1961..2161)
                     /locus_tag="TVW11_001458"
     CDS             complement(1961..2161)
                     /locus_tag="TVW11_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1365547.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2534..3271)
                     /locus_tag="TVW11_001459"
     CDS             complement(2534..3271)
                     /locus_tag="TVW11_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365548.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4022..4327)
                     /locus_tag="TVW11_001460"
     CDS             complement(4022..4327)
                     /locus_tag="TVW11_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1365549.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4329..4667)
                     /locus_tag="TVW11_001461"
     CDS             complement(4329..4667)
                     /locus_tag="TVW11_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1365550.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSLGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4695..5450)
                     /locus_tag="TVW11_001462"
     CDS             complement(4695..5450)
                     /locus_tag="TVW11_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1365551.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5711..6166
                     /locus_tag="TVW11_001463"
     CDS             5711..6166
                     /locus_tag="TVW11_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1365552.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6150..6800
                     /locus_tag="TVW11_001464"
     CDS             6150..6800
                     /locus_tag="TVW11_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1365553.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6910..7814
                     /locus_tag="TVW11_001465"
                     /pseudo
     CDS             6910..7814
                     /locus_tag="TVW11_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8167..8442)
                     /locus_tag="TVW11_001466"
     CDS             complement(8167..8442)
                     /locus_tag="TVW11_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365554.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8865..10415)
                     /locus_tag="TVW11_001467"
     CDS             complement(8865..10415)
                     /locus_tag="TVW11_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1365555.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11086..11646)
                     /locus_tag="TVW11_001468"
     CDS             complement(11086..11646)
                     /locus_tag="TVW11_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1365556.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11624..12493)
                     /locus_tag="TVW11_001469"
     CDS             complement(11624..12493)
                     /locus_tag="TVW11_001469"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1365557.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12585..13856
                     /locus_tag="TVW11_001470"
     CDS             12585..13856
                     /locus_tag="TVW11_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1365558.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13892..14230)
                     /locus_tag="TVW11_001471"
     CDS             complement(13892..14230)
                     /locus_tag="TVW11_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365559.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14330..15418)
                     /locus_tag="TVW11_001472"
     CDS             complement(14330..15418)
                     /locus_tag="TVW11_001472"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1365560.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4832 a         3442 c         2720 g         4646 t
ORIGIN      
        1 taggccaatt ttaataataa ttcttgtgta ccaaaggttt gtacggatac aaatgttaac
       61 agtttgttca tcaaaccttc tggaaaaatt cccattagaa agaccggtgc atatacaata
      121 agagcagata taccaaaagt ggttagagga gacttagtta gagatgaaac tagtgcatga
      181 atgcctgtca taaatatcag gccaatatac tgaaacacca ataaatagac aaacgcaatg
      241 cctaaggtca tcttttccgg gaaagccata atgtttatca ctggatcaat ccaatacaaa
      301 ttgagttgta agctagtgtc ccagccgcta aaaccaaaat aggtcgcaaa gacagcaaag
      361 accagaccac tagcaattgc aaataccaaa gtactgacag ctatgctaac tgctaattta
      421 gcaagagtca atttaccacg tccaaaaaca gtcgtcaata agatagagtt catcttttta
      481 gatgattccc ctgaaaataa aggagccgtt atataaagac aaagcataac aacaagaaga
      541 taagtactat tggttacatc aaacaactga ttccaaggag caaaattacc taacttcaac
      601 tctttcaaag gcagagcgga ccccaactct tcacgtgatt tgagatgaac attgtcaaat
      661 gtcagagact tatcagtgct attaatagcg ataagcttat cagtagactt aggcactaaa
      721 tgagagatag cataatgtga taccacacta tatacaccct tcttttttag gtctgattga
      781 tttttagcat aatcattgag gatacgacta atcagatcgt cagataaata acctgtatgc
      841 ttctcagcaa tttgttggtt aattgctaca gctgcacgtc catgaacctg atctgcagaa
      901 gagccactga tctgaccgtt aaaaaaatgc tggtaaaaaa gaccacctac agccaataag
      961 accactacaa tcgcaccaaa taccgactgt cgtcttaata attttttaaa ctcaaagggt
     1021 atgagagatg ccatagaatt cactcctttc taaaatgata aatgtagaga tcctctaatg
     1081 ttggtgacac aggatttgcc tgataacaag gactctcatc gctcacaaca cgtaagatac
     1141 gattattttt tacaattttt tcattgacaa cggcatagtc agtcaaaaat gctggtgcac
     1201 tctctgtagc aacaggaatc tcccatacct tgccgatcat tgtttgaact aactgatcaa
     1261 cacttccttt ttctataaac tgaccatgct ttagaaggat tacctccttt gcaaccgctt
     1321 ctacatcaga tacaatatgt gttgatagga taataatttt ttgctctgat aaatcactga
     1381 taatatttct aaattttaca cgttcctttg gatcaagtcc gactgttggt tcatctaaaa
     1441 ttaacagtaa aggatcgttg ataagtgcct gagcaatacc caatcgctgc ttcataccgc
     1501 cagaataaga agcaattttc ttttttctaa catcataaag acctaccagc tttaataacc
     1561 gatcagcttc tactaaagcc tttttacgtt taacattctt caaagcagcc atataaagaa
     1621 ggaattctaa accggaaaac tgctgataat aattaaactg ttgaggtaaa aagccaatat
     1681 tctggtaaaa gttttttggt tgttgttgat gatttaaact aatttctcca ctatcaggaa
     1741 ctgtaaactg actaatgatg tttaataaag tcgttttacc ggtcccattt gctcccaata
     1801 acccatacaa gcctggtgta aattgtgcag aaatacgact caacaccttt ttacttccat
     1861 aagatttaga aatattatct agtattaaca acattgtcat tcctcctaag taaaaaccca
     1921 gggaacagca ccacttcgct gctccccaga tgattaacca ttaagcatta tatactcgac
     1981 aaacggtacc aggataaaga atcatgtggt tatcagcatt ttcttgtgct gtatctctta
     2041 atagatgcca tgcacttgta taaccatcag tgcatctcca cctataaccc caaccacctt
     2101 caacgcctgc aagcatatca gcagtcattg tactaaattg ttcaattgtt tttgtattca
     2161 tatcgaatac ctccttataa tgattttatc tagctacagt ctcgacaaac ttagtgtagc
     2221 gctttttaaa gcaacgacac tcaaaaatct tgaatggttc ttattttgtc gtgaatggtc
     2281 aatttttctt ctgaaattac cagttaagat catatggata cctttcacga gctatatctt
     2341 tttctctctt ttcttatgat ataattgatt tttgcatgta catcatatct ctgagcatca
     2401 ttagaaacca actgttaccc ctttttctta gttttgacta aatatattta taataaatat
     2461 cccttaaggt aaatggtatc aacgaggttg attaaaaaac aaatgatggc ttccacatgg
     2521 cattctttta ctgtcaatgc aaagccttaa tagacgcctc aagtgctttc atttttagtc
     2581 ttgaaaccat gcaagactgc ccattcttga aatagagtaa acgcttatca cgatcaagaa
     2641 acgaaacatt gtaaggattg ataacataag aacgatgaca ttggactagt ctggaatctt
     2701 gcttaagaac ctctgaaaga aagccataaa attctattcg ctcgttttga gaatgcaaaa
     2761 tcaacttgtg aggagtacta gaggtctcaa tgaacaatag gcttgaaaaa ggaacctgca
     2821 cctgagcctt agccgttgca aaaataaata agccctctga ggttacattt tcttgctctt
     2881 cataagcata tataatggct ctttcaatcc tatctgagaa atgtttcatt gacaattcct
     2941 tatcgataaa atctagagca gacacctgat aacgaaaaga aactggcata agctcagaat
     3001 gtgtggtgac aaaaacaatg agggcataag ggtcacgctt tctgatctca cgagcaacag
     3061 ctaagccctt tttctcatca tttcgaattt gaatatcgag aaagaaaagc tgatgcctgc
     3121 ctctctctgt aacatttgcc agaagctggt agggctttcc ataaacttca aaacgatcac
     3181 aagtccagtg atgcttatcc aatatctctt gaatcttcat ctcaagccta aactgttggc
     3241 ctagatcatc ttcgagaata aaaatattca tttagaacct ccttattgct ttagcttatc
     3301 gtttttttag gagactaaag cagctttttg aacaagtgat agctagaacg ctctccttca
     3361 tgaacagtat ctttttagca tcaccattaa aaccatgacc gttaagctta ttaactaaag
     3421 gttgtcaatg acttctaacc aacttgtcat tgcagcgttt tcaataggcc ttagcgaatc
     3481 acgcgcctca aacaattttt ttaccacaga taatatacta gcacgagccg caagtcatac
     3541 ctctttgaga gagagctctt aacgactatc acttttgttt gacaagtcat cagctatcaa
     3601 tccacacact gatctccttg cacagacatt ctaacacaaa gctagggagc agggagttaa
     3661 aatcttaaat ggtactgatt atgtcttaaa tggtaaataa ggaaaactaa caatggctag
     3721 tcaggttact gaggctatct gatgattagc tgcttgtagc tataccttct ccaagcaata
     3781 agtttctaga attattggta acaaatacat taggtatccg ggatattctg tcatttattt
     3841 tatcataaaa acaatctttt tatcatcaaa acaggtaatt gttattatta ttaatcactt
     3901 tgagtgattt gaagtaagct agatcttcag ctaaacctta tgacactaaa cacaaaaagc
     3961 cccctaaggc agctaaaaca ccagcctagg gggcaagatt caagagagtc actctatact
     4021 tttagaccat ttcaatttgc aggtatttac aatttgttgc agcctctaaa tgataaaact
     4081 gatgagcaga gatactgatc aatccgcctg ctttcatgtc atgagcctga tccgtaagac
     4141 taaccagcaa ccttccttct aagacaagca ggagcttacc ttcagggctt gattcgttac
     4201 taatcgtctc tccctgatac atggcatata aaacaacaga ttgcttaaag cctaggcttt
     4261 gatgaagcga acgactagct atttggtcat catgatacct tactaattct aataaatcag
     4321 ccaacatgct aagcctccgg ctttacaaca actaaaagca tctggaaggc ttccttagca
     4381 aataagctat gaggaatatt agcaggcatg atgatcgtct cgccagcagc tacctcataa
     4441 caggcttctc caatagtaat gtcaactact ccacttaaca cgttaaccat tgcatctccc
     4501 agtgatgaat gacgaccgat ttcttgtcct ttatctaatg aaaacagggt tatgcccaaa
     4561 tcttttcttt gaactagtgt tcgacttaat atttgatcct cttcaattgg cacttctgcc
     4621 tttaaatcaa tgactgtgct tgttggaatt ttacgaatca atgacatgtc acttctcctt
     4681 taccattatt ctagttattt ttgacttaca gcggcaatat aacacagctt tcttccagtt
     4741 ttgttgaaga aatgacgcat ctttaaaaac tgctttcgat tttctttttt catgccgcgc
     4801 agcataatac gaatcgcagc gacaacccct tcatctttaa tcatgccaag cggggacatg
     4861 agcgtcatat taccatagga gtaattgact gctgtgaagc cactctttac cagcaattgt
     4921 ctccaggcat ctaactgcaa tggcgatacg ttcacattaa tcgtatctct tagttgctct
     4981 ataatagcct ttgtttcatc agcttcatag gaaacatcat gcgttagtag gcgaccaccc
     5041 ggctttaaaa cacgccaata ttccttaagt gctttttcct ttgcagcatc attcaacatg
     5101 gttagcatag cttcgttaat aacgatatca aagctattat ctgcaaaagg cagcttcaag
     5161 gcattagctt gggtaaggtg aatatagtct tgcatttgtg ctgcctcaat agcctttctt
     5221 gcctccgcca gtaccttggt atccaaatct actgctgtaa tatgacactg ataagtctgc
     5281 gccagctcaa tggaggtcgt gcaacggttg caggccactt ccaagacctt gcaatcactc
     5341 gaaaactctc cttgctgaac cagccaattc gtcgcctcaa caccgccagg ccgtagtcgt
     5401 ttctttccca gtcgagctaa aaactggtga ccaacttctt tttgagacat cacatgccct
     5461 cctatttgct ctgctatata tcatcactta gaataaacta actgttaaca aattgatcaa
     5521 taaatgatta ctacaactat atcacactta aagcatatcc tcaatgaagc ttaagcattt
     5581 ctgatgattg tttttatgat aaatcataga attggctcat atttcttgtg ctatacgacc
     5641 ttttgacttg ctattatttt ttaaataata tataatctag ttatcaaaac tagataaaga
     5701 ggttttagta atggaatatg ataagctgcc cagctggaag gatttacctg atttggagtt
     5761 atacttagat caagtgttac tctatgtcaa tcaggtcaca caattgagtc aagccacaga
     5821 ccataagcta ctgactgctt caatgatcaa taactatgtc aaacatggct atattgataa
     5881 acctattaag aaaaaatatc aaaaaaagca ggttgcccgc ttaattgcta ttagcatttt
     5941 gaaaaatgta tttcctattc aagatattag tcaggtcttg acgagcctac aagcagcctc
     6001 cagctcagag gtcttgtacg atacctttgt caactattgg aataatggcc ttacccaatc
     6061 aacgcctgaa attattagct atgcttgtca aaccgtcaag gactatcagc acacaatgaa
     6121 gctttcaaga gaaatggagg ataccaagca tgaaccaaac ctttaaacaa agtctcccac
     6181 tatcagttaa tgaagaggtc gcaaatagtg tgacacacgc tattggagca gctgctatgc
     6241 tgatactgct acccatcact gctatttact cttaccagac ttatgatctc aaggctgccg
     6301 ttggagcatc tatttttatc atcagcttat ttctcatgtt tttatcatca acgatttacc
     6361 attccatgtc ctatggaaca actcacaaat acattttacg tatcattgat catagcatga
     6421 tttatattgc tattgctggt agctatacac ctgttgcctt atccttggtt gagggcttgt
     6481 tgggctatgt gattatcata ctccagtggg gaatcacact ttttgggatt ttgtataaaa
     6541 tttttgctaa aacgattaat gaaaagttca gtcttgcgct ttacattatt atgggctggt
     6601 tggtcgtttt tatcctgccg gtgattatcc aaaaggccag tctgccattt ggaatcttga
     6661 tgctactagg tggcttatcc tatactgtcg gcgcaggctt ttatgctaaa aagaagccct
     6721 attatcacat gatctggcac ctttttatcc ttttagcctc tgctttacag gttattgcca
     6781 ttattttcta tatgctgtaa aaagtagctg ttgctacttt ttaaacgcga gcgcttgctt
     6841 acccccagac acctggcttg attcatgcta taataaaggg cagtaaatag ttgaagggat
     6901 caaagcaata tgaaaacggt acatattttt tacaatccta attcaggaaa accagaaaat
     6961 gacctggctg aaaaggtcaa gcattatctg attcaaaatg gtttttctga agacaaggtt
     7021 cagattatta cccccaaaaa tgctgatcaa gcctttcaat tagccaaaaa atcctcacag
     7081 gatcatattg atctagtcat tcctctaggc ggagatggga cacttaataa aattattgga
     7141 ggtgtttatg aaggtggtgc tcattctgtt attggactcg taccgtcggg cactgtcaat
     7201 aactttgcaa aggccttaaa cattccactc cagctaactg aggcacttga gacgatttta
     7261 tctggcacga ttaaaaaagt agatatttgc aaggtaaaca agggctatat gatttctagc
     7321 ctaaccttgg gtctgcttgc tgatattgcg gctaatgtga ctacagaaga aaaacgaaaa
     7381 tttggccctt ggccttttta aaggatagta ttaagatact aaaacgaaac cgcacatatg
     7441 caattagctt aattagccat catcatgttc ttcacttgaa aaccaaattc ttattgatta
     7501 ccacaaccaa tactatagca ggtcttccat cgttttcacc aggtgcacaa gctgacgatg
     7561 gcttgtgtca agtttacacg atgagccagc tatcatttct gaaatgcttg cgccatatta
     7621 gagactttag acggggggat ttttccaagg taaaggagat tagccatttt caagctgatt
     7681 ctctaaagct attgccacaa tatcagcgtc aatcagccat tcctagaact cgcattgatg
     7741 gcgataaggc tgatgatctc cctgttgaat tgaaggttat tccaaaagcg atttccatta
     7801 ttgttagcca gtaaaaaagt gccctagggc actttttgat atagattcat ctccaagctg
     7861 agttttagaa aactaagcta tagctataac gttagctgtg gcttcttctt gctggcttgc
     7921 agtactcttt tcttgtctta acagctagct ctttcataat atcggcttta acaaagaagc
     7981 tatctgacta gtccgatctt ctattctcag gacaaacagc gagaaagggg attttctttg
     8041 aatcctagag aaccttagct atctctgtgt ctcattgtaa gtgcagctct attgactgat
     8101 gccagctata gcaataagcc cagtcgcata ttataaagga ttatcaggcg atttagcttg
     8161 acactcttat atctttattg cttcttctaa ggttccttta atagctttag ctgctgaatg
     8221 accacaggca ttagcagcaa ccttagaggc ttctacctta tcagaggctg tctcaataag
     8281 ttgtccaccc ttttcttgga tataatggtt caactcctca atagtttcag agccttcctt
     8341 taagagctct ttctttttgg ctgaggataa gcttaaatat gtcacagcaa ttgctgctga
     8401 accaagaagt aatcctaagc cgattccata gctttttttc atcatcaacc ctactttcta
     8461 tgaccttcct taatcatctt tttagctaat tttacagctg gtactactaa aagcaccaat
     8521 tgtaaaagat ccatatactt gatttttcgt cgttttttca ccatgtgcta tttccttttt
     8581 cttgtttgca ccatacaatc gtcttttatt gcgcagtgcc agagactgcc tgattaggca
     8641 gcgtaagcta agaactatca gcgtgtcaga ctagtctaga tacagctaag cactagcttg
     8701 attacgataa tacttaccgc taggccataa gctcagctat catcaaatct aaagtgacaa
     8761 cgctttttat ttattatatt gtcattttac taaaatacac aattatcgtc aatgcttttg
     8821 ctttaggcag caaaaatgcc caagataaag accttggaca tctgctacaa tgacgttaat
     8881 tgattgaaat cccaaatatc agttacccag ccctcataaa actccggctc atggcaaacc
     8941 atcaaaatag agcctttata gacttgcaag gcgcgtttta actcctcctt agcatctaca
     9001 tctaaatgat tggttggctc atctaggatt aaaacattgt gctcacgatt cattaagaga
     9061 caaaaacgaa ccttggcttg ctcaccaccc gagagcccct gaatctggct ttcaatatgc
     9121 ttagaggtta gaccgcaacg agctaaggct gcccgaacct ctgcttgatt taaagcagga
     9181 aaagcgtccc atactgcttc tagtggcgtt tgacgcttaa cacctgcagt ttcttgctca
     9241 aaataaccaa gctccacgaa atctcctgtt tccacctctc ctgacagtgg ctgaataatg
     9301 ccaagcaggc tctttaggag ggttgactta ccaataccat tagcaccgat aattgcaact
     9361 ttttgatgac gctcaaatgt taagttcaag ggatcttttg ttaggggtct gtcatagccg
     9421 atgacaagct cccttgtttg gaaaataaag cggcttggtg ttcttgcttc cttaaactca
     9481 aagcttggct ttggtttttc tgcctgaagc tcaatgattt ccattttatc aagcttcttt
     9541 tgacgggaca tagccatatt gcgagtagct actctggcct tattacgatt gacaaaatcc
     9601 tgtagctctg caatctcttt ttgctgacgc tcataggctg cctctagctg agcttttttc
     9661 atctcataga cttccttaaa ctgatcgtaa tttccagaat acctaaccaa attccgatta
     9721 tcaacatgat aaacaatatt aatgacatca tttaaaaaag gaatatcatg tgaaatgagc
     9781 acaaaggcat tgtcataatg ctgtaaatag cgctttaacc actcaatatg ctcagcatca
     9841 agataattgg tcggctcgtc cagcagcaaa atatctggct tctccagtaa cagcttggcc
     9901 agcagaatct tggttctttg ccctccagat aaggaggtca cttctgtttc catcccaaaa
     9961 tccataactc ctaaggcacg cgcaacctca tcaatcttag catctagggt ataaaagtcc
    10021 ctgctttcaa gacggtcctg tagctctccg acctcctcca ttaaggcgtc gacatcagct
    10081 gtctcctctg ccatagacat gtaaatggca ttgatacgct cctctgtttt gaatagctca
    10141 tcaaaggctg tcctaagaac atcacgcaca gtttgaccag gttctaaaac ggtatgctga
    10201 tccaaatagc ctgctgtaac atactttgac cattcaatct taccagcatc aggctgcaag
    10261 tgaccagtaa caatactcat aaaggtggac ttgccttctc catttgctcc tactaatcca
    10321 atatgctcgc cctttaaaag acgaaaggaa acatcttcaa aaatggcacg atcaccaaat
    10381 ccatgactta actgcttaac ttctaatatg ctcatgatta ctttccttta ttgtcatcaa
    10441 aaaagccgtt aaaacggctt acactctctc aattatggca aaaatgcagc cttttgtcaa
    10501 tgaaggctga aaaagcctac gtcatacgca tgaaagattt ttagcaagaa cagaaggttt
    10561 tttgcatttt aatgttcagc tatttcaaat atgtcttatt attttataaa ttttactata
    10621 gggaaagcct tgaaagtgcc tgctttaatt tatactatca ttcggaaaga actgtttcgc
    10681 tcgtttgttg tggaaagccg ctcacaacaa agacatagag agtctatgac aacaagagct
    10741 acactttagc aagtcttgac cgacatgctt tattgcccag tctaattcat taaaaagcga
    10801 acaggtctag ctttcggaat ttcagaaaac taggcctgtt catttgttct attttgaggc
    10861 agccttttgt ttcggcctcg tctgtttcaa ggttttcaga tcgaacttaa ggacaaaaaa
    10921 cactctcctg tatcagctaa ccttatcatt cattataaag gaaaatgatt tctaatacaa
    10981 ggaaataccg ttatttcatt aaaaataact aaaaatagtt tgtcaaatca ttagttatta
    11041 ataggcttag ataacaaaaa tgatgatact gctagcaagg ttagctcaac caagcctatt
    11101 actcgcttct tgctttttta ctgcctgcct taattgctta aaaacagggt ataagagagg
    11161 cacagcaata acggtcacaa gggcagtacc aagactgcca ccaattttgc caagtgctgc
    11221 ccacaaagca acagacaggg gtaactgggc gccaaaataa gcaatcaagc tatatttcac
    11281 aagattcatg actaattttg ctgctgctgc taataagcca attgctacaa taatcatcgg
    11341 tttatcaact gatttcagaa gtttctcata aatcacatga agcaggtaac aaaccactaa
    11401 ggcttcaagc actgttatcc agaccacagc cgcatagcca ttaatcatat caaacagtcc
    11461 tagaccaatg gctgccacca aagctgccct tctagcacca tacaataaaa cagccaccac
    11521 cactaaggca ttccctaggt gaataaattg ggctccaact ggaatacgca gcagctcaac
    11581 cgatataaaa ataagagcag caaataggct aagctcgatc tgatcagtca atcgttttga
    11641 tgtcatcttt ttcctccaat aatcctctaa acgcggctcc caagctgccc aattctactt
    11701 cgtaggcaat tccaagtgaa agctctcgat ttagcgcaac agtagccgct aatgacttgt
    11761 ctaagaagct aataaccata tccaacaact catcaatagc aagcctgtga aaatacccag
    11821 cgctaacaat agcagagaca agatcacctg tcccatagaa atgataaggg taccgttttc
    11881 caaaatgata gctaaccgtc tctgttgcct tttgataata agcaaagccg atgtgctgat
    11941 catcaaagga tataccagta aggacaatct ctctaggtcc tagtgtagct agcttagaca
    12001 atagcctctc caaatcctct ctgctatagg tctccccaaa ataaggaaca tcagctaaca
    12061 aacaagcttc cgtcacattt ggcaatatca gctgtgcagc ttgagcgagc aatctcattg
    12121 ccgataagtg ctgcgaggtt aactgcgcat acatgcttcc cttgtcagcc ataataggat
    12181 ctagcacaaa gggaagctgt tgctttttga tgtaatcaag aataatcaaa gcatcatcag
    12241 gacggtacaa ataaccggaa aaaaagccat caaaggcaag acccgcttga gaccaagtcg
    12301 tcaaaaatgg ctttagtccc tctgacgtgc tctgaatata aggcgtctta gcaattgcag
    12361 tgtggcttga taacaaacag gttggaagaa tggcctgttc aatctggcaa gccgccataa
    12421 tgggaatact agcagacaga gcaaccttgc caactccgac aatatcattt gcaacaataa
    12481 cacgttttaa caaccaataa gctccttcat ttcttttttt actattgtaa gaaaatcctt
    12541 gatgagatac aataaggata gatttcatct gtatggggac acttatgaca agtaaatatc
    12601 aacaaatcat tgcagaccta gagttggcca tgcaatcaaa ccaattcaaa aagggagaga
    12661 aactcccttc tattagacaa ttaagtcaac agtatcactg cagcaaggat acagtgcaaa
    12721 gagcactttt agccttacaa tacaagcgcc tcatttatgc tattccaaaa agtggctatt
    12781 atgtgcttgg taaaattgag gaaaagcagc attcctttga gctaagcctt gaggattata
    12841 atcagttggc ctatgaggac tttcggctct gtctaaatga agccctagac ggtaaagatt
    12901 ctgatttatt taactactat cataaggctg agggacttga ggagctgcga gaggctttgc
    12961 tgccttattt ggctgataat gggatttacg ctaacaaaaa tcagctgcta attacctcgg
    13021 gtacacaaca ggccctttac attttagctc aaatgagatt tcccaatggc cgccatcaca
    13081 ttctccttga gacaccgacc tatcaccgaa tggagcagct agcgacttcc ttaggcttac
    13141 cctatcaaac cattgaacgt gatgtcaacg gtatcaatct tcatcagctt gaaagcatct
    13201 ttaaaaccgg acaaatcgct tttttctata ctatttctcg attttcaaac cctcttggcc
    13261 tctcctacag caaaaaagaa aaggaaagca ttgttcggct ggcagagcaa taccaggttt
    13321 acatcgtaga ggacgattat ctaggggact ttgcatcgca tagtgagctt ccgctacact
    13381 actacgacac tcaacaccgg gtcatttatc tgaaatcatt ttcaatgagc gtctttcctg
    13441 ccctgcgcat tggagccttg cttttacctg atgatctcaa ggaaggcttt ttgttacaaa
    13501 agtcaatgat tgaccttgat accaacctga tcatgcaaaa ggcactagca ttatatttag
    13561 caaatggtat gtttcaaaaa aacctaaagc aaatgaggca atttttcaac aatagagcgc
    13621 ataacttact agattttcta caaaaacacc ttcctaacct agcttatcag ctcactcctc
    13681 aagcactgat tattcaatta gataaagcat tcaatcgcaa aaagcttctt aaaccacacc
    13741 acacccaaat catctcaaca agaaaagcaa ggtatatgct tctaacaatc agtcctgata
    13801 tgccatctaa gctgctcgac ttgttttcag tgacacatga aaagacccaa gaatagctca
    13861 ttgggtctca gtgtcacaaa aatgtcaata gctatttgat ttgctcgaat cgtaaatgaa
    13921 cactaatgct atcgccgtaa ccgtttctct ccaaatctct ttggagccgg taagcaatat
    13981 aatgctctgc aatagtcatg tagcctgcgt caatcagacg attttcaaca agtgattgaa
    14041 tcatattaat cgtcggacgc tccgcctgca cctcttctag atcaataaca acctttttag
    14101 ttacctgagc tagatgctgt ctccagctgt catcaatcac ataaactgtt cttgctgcct
    14161 tgatcaaagc ctgataaatc ttatccggat caaagtctgc cagctgaccg tcacgcttaa
    14221 taatttgcat aagagcgcct cttttcattt agtttcattg cttacattca ttatgcaaat
    14281 gttttcatca tttgtcaagc tattaggctc ctatgcctct tagggattat cagtcaaaag
    14341 aaacactagg atcaaataaa ttgtcctgtg ctggtcggac aagcccacgc tcgtgcaagg
    14401 tctctgcaat ctgaacagaa ttccaggctg cgcccttgag cagattgtca gataccaccc
    14461 acatgtgaat gcccttttca acatctaaat ccttacgaag ccttcctaca aaggtctcac
    14521 gactgccaac agcattaacg gcctgtgggt atcgttgcac tccggtatcg tcctctaaaa
    14581 cagcacccgg aaattgtgca atcgcctcct taacagcttc gatagtagct actgccttgg
    14641 tttcaatgta gatagattct gaatgggctg ataaaacggg tatacgaaca caggtcgcag
    14701 acaccttaat cgtatcgtcc tccatgattt ttttcgtttc atttgtcatt ttcatctctt
    14761 cataggtgta gtcattttca gtgaaacgat caatctgtgg taaagcatta aaagcaattg
    14821 gataatgtct cttgtcacca gctgacggta aaacacttgc ctccacctcc ttaggagaca
    14881 agccctggtt aataacctgg tcatactgag ctagggtctc acgaatcgct gattgaccag
    14941 cacctgaaac agcctgatag gtggaaacaa taatacgctc aagaccccac ctttgacgaa
    15001 taggctccag cgctatcatc atttgaatcg tagagcaatt agggcaagca acaaggcctt
    15061 gatgtgtatc aagagcgtga gcatttacct caggaacaac aagtggaaca gctgggtgct
    15121 gacgaaaata agaggtattg tcaaccacaa cagcacctgc cgcaacagca taaggggcat
    15181 attttgcaga aacattgcct cctgctgaaa aaagggctag atcaatgcct tggaaggctg
    15241 cttttgttag ctcctcaaca acaaaatcct ctcccttaaa tgagaggatt tttcctgctg
    15301 aacgtgcaga cgctaataat ttaatagctg aaataggcag acttgactcc tccagcatct
    15361 taatcatttg ctgaccgaca gcgcctgtcg ctccaaccac tgctactgta taccccatag
    15421 atcgacctca ctttaactga tgatattgca aaaaatgata ttggacctat tatagcctat
    15481 ttcatcacaa aagaaaagca agctagaagc cagaacaaac gcatgaagaa aatcatttat
    15541 tgaaaaagtt gtgaaaatag caaaatatcc attttagagt attttgacag agtgtttcct
    15601 gaatttttat atttttcctc tataaacttt tcttgaaaaa
//
LOCUS       DARYUW010000047        15117 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYUW010000047 DARYUW010000000
VERSION     DARYUW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15117
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TVW11_001473"
     CDS             complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TVW11_001473"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1365561.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2578..3231)
                     /locus_tag="TVW11_001474"
     CDS             complement(2578..3231)
                     /locus_tag="TVW11_001474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365562.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3271..3900)
                     /locus_tag="TVW11_001475"
     CDS             complement(3271..3900)
                     /locus_tag="TVW11_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1365563.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3902..4903)
                     /locus_tag="TVW11_001476"
     CDS             complement(3902..4903)
                     /locus_tag="TVW11_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1365564.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4936..5577)
                     /locus_tag="TVW11_001477"
     CDS             complement(4936..5577)
                     /locus_tag="TVW11_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1365565.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5612..6406)
                     /locus_tag="TVW11_001478"
     CDS             complement(5612..6406)
                     /locus_tag="TVW11_001478"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1365566.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6715..7149
                     /locus_tag="TVW11_001479"
     CDS             6715..7149
                     /locus_tag="TVW11_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1365567.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEAEEADLDEGGI"
     gene            7149..8348
                     /locus_tag="TVW11_001480"
     CDS             7149..8348
                     /locus_tag="TVW11_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1365568.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFENGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8394..8882
                     /locus_tag="TVW11_001481"
     CDS             8394..8882
                     /locus_tag="TVW11_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1365569.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8897..9676
                     /locus_tag="TVW11_001482"
     CDS             8897..9676
                     /locus_tag="TVW11_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1365570.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9663..10484
                     /locus_tag="TVW11_001483"
     CDS             9663..10484
                     /locus_tag="TVW11_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1365571.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10884..11885
                     /locus_tag="TVW11_001484"
     CDS             10884..11885
                     /locus_tag="TVW11_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1365572.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
     gene            12475..12741
                     /locus_tag="TVW11_001485"
     CDS             12475..12741
                     /locus_tag="TVW11_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1365573.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            12753..13112
                     /locus_tag="TVW11_001486"
                     /pseudo
     CDS             12753..13112
                     /locus_tag="TVW11_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13103..13984
                     /locus_tag="TVW11_001487"
     CDS             13103..13984
                     /locus_tag="TVW11_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365574.1"
                     /translation="MGVTYSAAESKALIQAMTNNIQIANEITDRLSSGCDHLIASLDS
                     GELQGAAYTAGRGLFTAIIIPSIKKLQAAIDAIQVELTTYQRADAQIARYGTLDRDHL
                     TELKRLRERQVQVIQAQIDENESFMKQVSSLLTGDYGTLWSDTSTLYHAKNQLEIGIR
                     DVTTKLESLEWFLTQTSDCFRDSLVILRLAIQGATQLSQVFMSSDGSYSTAGLDMSWV
                     TSLKNQKISPVNASKYTQNHYHNILTQTIKTIKSSSERPLQKSERLVAAYEDYLYFLN
                     KTAFDDYWKARSNYDGE"
     gene            14081..14509
                     /locus_tag="TVW11_001488"
     CDS             14081..14509
                     /locus_tag="TVW11_001488"
                     /inference="COORDINATES: protein motif:HMM:NF026945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365575.1"
                     /translation="MGDDILSVNVNAPYLSQVAGSQLSAAILDNKQFYDLVNTGQPLD
                     LKSRTYHGHNYSVWSRQWESELPGDYAGNYLYGYVGTGFLDASGTYLKTAAEIAQVFS
                     DKDIPKWLKNLSSGHYGDNEGDTQMIQAGIDGYMKRKKSK"
     gene            14506..15012
                     /locus_tag="TVW11_001489"
     CDS             14506..15012
                     /locus_tag="TVW11_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365576.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
BASE COUNT         4357 a         3363 c         3096 g         4301 t
ORIGIN      
        1 agctcagggg ggattttaac ttattactaa tgtgcttgaa tggctatgat aaggccttaa
       61 aagatagctg cttaaagtca tttcccacct tttgatagag gtataagcct gatttttcaa
      121 gactcaattg accattaacc acctccttag cctgattgta tttgaccacc gccaacaggc
      181 cttgtttctt atcatggatc agctgaagct tactgtcatt tcgaagcacc tcaatacgtg
      241 cttcgctgca caccttgtca aagtctgctt tgctgatatt tggaagtagg gtgtaggcat
      301 agctatcact agcctgagaa tgagtttgac tgattgtgat aaagctttgg gagatgaggt
      361 ctttattgtt actatttgta ttaatctcag accaacagcc tgactgcacc tttcgcgata
      421 gcgctaatgc ggttggcttg gcaaaaaggt aaccaatatt agcttgaccg tctttagaaa
      481 gtagtaaaag actggtcaca tcatctcgat acaggatctc ctctgttagc gctgtctcct
      541 gcccattgat aaaaagagtg tagctgttgt ctgggttttc tttgcgttga tcaatggtag
      601 tagtcactgc ctgatgtgtc tgactagtga tggcggtgcc aagaaaaaca atttggtcat
      661 ctaagatcgt ccaagacttc ttggcactca ctgtcctatc ccaattttga aaatccataa
      721 cagctaaagc tgttttgtct cccgccttga tcgctccaac aaaggacgat ggcagggtag
      781 acatgcctgc tttttctttg gccttttctt tataatcatt ggttagcttt tttaaatagg
      841 ctactgtcac gtcctctcgc ctgacctctg cttccgttgt tccagccatc tttaaaggat
      901 taacagtcgg ccaaaagtgg tctgagtaat gacccaaatc actgttataa aggtaaaaca
      961 tgccatctcc tgtataccaa ccacgtgtat tttcatcgtt catggcttca aaattcagag
     1021 ttttgttgga atgcatggat aaagcaaagg caaaatcctt ttccgcattg tagtaggcca
     1081 atttatccat ctggttaaaa agagataggt agctcttaac tggactggct tggattgtgg
     1141 tatcctccaa gagctctttg aatagcttca tgtcatagta gcttgatagg ctctctaaaa
     1201 tagtctcctg attatggaag gccaaaacag ccttgatctt acccttgatc ctgattttag
     1261 cttgctctgg caatgcctca gccagtctta gcattcctct tagtgcttct aaggctgcct
     1321 gccttgagga ggcattttca cgactgatgg agcgcccacg actcatatcc atgagctccc
     1381 catgaaccat caagggcaag aaggcttgct caatccaatg agtcatgacc tctagctttt
     1441 gctggtctag gctagtagct aatagctgaa gtaatggtac cagctgagac aagccatcaa
     1501 taaggacatt gccataggct ccagtgtagg cgacattggt atggtcaata taagagccat
     1561 cttcataaaa gccctcaccc cttgatccct ttggctgaaa agcaaataag gtatctaggg
     1621 ctgctatact gtcttgaagc gctttcttat catgctttaa cagagcttca ataatcttca
     1681 ctcgtcccat atcaacaagg ttacccccaa tggccttaaa aggattcaca agggttaagc
     1741 gaaattgtct aggattagga acaaagtgag aaattccttt agtatagcgc ttgatctcct
     1801 cttgagtgac ataagggtaa atgaaggcta gggtattgac aatagctctt ggggtaccaa
     1861 tttcaaaatc ccaccaatta gccttgcctt caatatcctt ttgcggatga tagtaattaa
     1921 gtgtcagcca ggctaattta tccttgatca gtcttatcag ctccttatcc tgataatacc
     1981 tagaggctag gctactcacc tgcttggcca tttcctctaa acgcctacag gtagctgtca
     2041 tatgagacga ttgatgaaga tccgccaaat cactccaaag gtatgtgctt ttctgatcct
     2101 tggtcagatc agctagattc ttggtcacgc tgtcgtccag tttttggttt aatgccacca
     2161 tggctggact tgatcggtca aagttttctg ctcccaaaat cacctcacac cactttgtga
     2221 tcaaggaggt tgtttgaggg gcttctgctg ctaaaatctc aactggtacc gttgctactc
     2281 tttgcccctc ttgatccaac acctctaaaa gcgttttccc ctgcgccaaa ggaattaaaa
     2341 gaccattttc cacgcgcaca atgttgctgg actccgctgc aatctgataa tgatagtcag
     2401 ccatttccat gaggtagtgc ttatttaaag gcaggacgat ttgctcctct aagtaatgtg
     2461 aagcaatctt gatgtcatca cttggcttat caccagcctc tctcaaagaa aggttatcaa
     2521 agaccacctg tccatgaccg gcctcataaa agagctctag cttgatttga ttaaccttta
     2581 gcttagggat ataaagcttt tcttggtgtt ttttctcagt tcctgttgcc atcgaagcca
     2641 caagcgttgc tcttttgcag caccagaacc ttgctttatt tcttcaatga tacgcgcaaa
     2701 agcctgacct gttttatcct ttgtctcaat gtcaaaggtc agcaaatact gcttgtctgg
     2761 attgatggca acggtttggt gcacacagcc tctaaatctc tgattgccat cgctagtcat
     2821 tgtcagcttg ttatcagaga cagcaatttt aggacagccc tgactcttac tagcgtcctt
     2881 ataatccttc caatcatttg cagactcctt gctccaaagg cttgtacttt gatgctcttg
     2941 agcaggactg gtctgatcaa attgaggatt tttaagcagg ttatcacctg tgagaatgag
     3001 ctgctcccca agactggatt ccgtagctac tgacgacgcg tcttgagtgt ctggggagct
     3061 ttcttgagaa gcctcctcag tttttagtgg tgctttcttt accctctgaa gctccttgga
     3121 aatggctttt gctgctgttt tttcttctgc taagactgtt ggtgcccgaa ataaacaagc
     3181 tagtatgata ctagagcaaa cagaagatga tagttttttt ctttgcttca tctgatacct
     3241 ccttgctttt ttaatgtttt atgaccgact ttaacagcta ctcatgtaat ctgcagccct
     3301 tgctgtgatt gcctgaaatt gaccctgagc tgccaattga ttaaattctc ctccaactcc
     3361 cagcacctga gcacctgcgg caaaccagtc tgacacattt gtgacagtta cgccacctgt
     3421 taccatgaca tcaacctgcg gcaaaggaga tttgattgcc ttaataaagg acatgccaac
     3481 tgtggcacct ggaaagacct tgaccatctc tgcacctgat tccaaggcag tcacgacctc
     3541 ctcaatagtc atacagcccg gaatataagc aatagcatat cgatgacata ggcggcttgt
     3601 ctgcctgcta aagctaggag acacaataaa ttgagcaccc gctaaaatag ctagccttgc
     3661 tgtgacatca tcaagaaccg tcccagcccc gatcaggatc tctggatcat tgccaactgc
     3721 ttcacgcagg cctgcaataa cctgactggc aaagggatta gtataggcca cctcaatggt
     3781 tttgatccca ccttcaatac ctgctaggct gcaagccatt gcttcttttt tagaagctcc
     3841 ccgaacgact aaggctaatt tattggcttt tagccttaac atgatttctg attttctcat
     3901 attaccttct tacctctcgg tttcccttca tcaccctatc aacctgacta acaggaacaa
     3961 agagctgatc atcagcaact gtacacttaa gactagctgt cgcagcagca aaatcaagcg
     4021 cagcagcaat agcctgtcct ctcatcaatt gatataagca gcctgcaaca aaggcatcac
     4081 cactgccaac tcgttgcaaa acaggcgttg atagctcaat ggagcgatgt aactgcccat
     4141 cataggcata ggctaggtaa tgattgattc cttggtcatc gatgtgacgt tccgtgtgaa
     4201 aaatggcttt taagtgatat gcctcatata aggcagccaa gcgctccttg acagcacctt
     4261 gacctgcctt agctctatca aacatggcat gatcagcttg attacacatt aagggctcca
     4321 taccaaagat caggtctgca tactgtgcaa aatgagagaa caatgtcttt gcctccctga
     4381 ctgaaatcat cgagctgcga aaattcaaat caaaggaaac acagacctgc cgcttcattg
     4441 cctcaatagc cagctgctca acaaggtcct gactgacttt tcctaaagcc aaggtaatgc
     4501 cactaaaatg aaaatgagta acttcctcaa atagtttacc ataatccaga tcttttgggc
     4561 ccaataaact aaagctagag gcagagcgat cataagcgac ctgactagga cggcagccaa
     4621 agccattttc caaataataa ataccaaccc gatcaccaca ccattgcaca tgctctgtgg
     4681 caacaccgct ttgcttcaaa aaggcctcaa cgcttcgtcc aacctgatta tcaggaaggg
     4741 cagtcagcag gctactctct gctctaaagc cactaagcgt tcttgcaata ttaacctctg
     4801 agccaccata atacagctgt gcttgacagg catgtcctaa cgtctgaaaa tgactgggac
     4861 tgatgcgaat cagcggctct cccaccaata ataccttggt cataggggta tcctttctat
     4921 agctgcagat aagacttatt gctgaaggac ttctcttagg tagtcgacaa ggtctgatgg
     4981 ctcggcatta gcaaagaaat aatgctggaa gtgctctcca gaaatggttt ccttcaagaa
     5041 atcttgatca atctccttta acacctccaa caaagaacga taagtcacag ccttcaattc
     5101 gctcaaaatt ctagcgttac gttgctctgg gatggcccgc tctttgggat agccgccccc
     5161 catcggctca gcaaataagc gctcaaacat cagggtcagg ttaagctctg ccccccaacc
     5221 aaagcccttt gcaaatggaa tagacaaggc attgccacca ttaatctgag caaaaaggta
     5281 ggcttctgtt ggctcactag caaagccaca ggtcacacct ggaaagctat ttaaggccag
     5341 catagcaccc acaccagtcc cacagcccgt tacaacaaaa tcagctgcct tacttgtcaa
     5401 taaaatagaa gctagtagcc cgttttgcac ataggtcagc tgactttcgc cctccttgcc
     5461 atacatacca tagttaaaga cctcatagcc atgcttatta gtaacagaga ctaaggtctc
     5521 gtaaataata ctgtttttag ctgcttgact gttttcatta attaatgcaa ttttcatctt
     5581 ctgtaatctc ctttgatgct tttttgtttc tttacggttg tttgccaatg taagctaaaa
     5641 tgcctccatc aacataaagg atatgcccat tgacaaagtt actcgcctca ctagccaaaa
     5701 atatagctgg accagccaga tctgctggtg ttccccaacg cgctgccgga gtcttagcaa
     5761 taataaactg atcaaagggg tgacggctgc catcagcctg acgctctctt aaaggtgctg
     5821 tctgaggcgt tgcaatatag ccaggcccaa tgccattgca ctggatattg gcttctccaa
     5881 attctgaagc gatgtttttg gttaacatct taagaccacc cttagctgcc gcataagcac
     5941 taaccgtttc acgaccaagc tcactcatca tcgaacagat attgatgatt ttcccatgcc
     6001 cttttttaat cattgatggc agaactgcct ttgaaacaat aaatggcgca ttcaggtcta
     6061 tatctaccac ctgacgaaaa tccttagccg tcatctcaag catcggtgtc cgtttaatga
     6121 tacctgcatt attcacaaga atatcaataa taccaacctc tttttcaatc tgagccacca
     6181 tctcttgaat ccctacttca tcagtgacat cacaaacata gccatgagct ttaatgccaa
     6241 actctcgata agctgctaat ccttgatcca ctaaatcctg cttgatgtca ttaaagacga
     6301 tctttgctcc agccatggca taggccttag caatctcaaa gccaatccca tacgaggctc
     6361 ccgttatcaa ggcaattttg ccctctaaag aaaagaaatg ttccattgtt ttacctctca
     6421 atctcaatat ttaagtaaac ctgtttatca aaactatagc aagactaatc cattttgtca
     6481 atcattttag taaaaacaca aaaaagagct aaagtttttc ttattgtcat tatcgaggaa
     6541 ggcttcttag ctatattttt cttgctctta ctcgctttac ttcctataag gatcccaaaa
     6601 attaggccat attgatcgct tattttgata aaataacaaa aaagtgttga caaacatttt
     6661 tgaaagcgct ataatttttc tgagtaaacc ggtaaactaa aaaggagctt attcatgatt
     6721 tctattattg ttattggtca tgggcatttt gccagtggta ttgtctcgtc tttagagtta
     6781 attgcaggca agcaagaggg cataactgct attgatttta ctgctgagat gaccgctgct
     6841 gatgtgcatg agcgcctatc agtagtctta cagtcaaaga ctcaggcact tatgctttgt
     6901 gacttattag gcggcacccc atttaaggta gcagctacct tgatggagga gctttctgag
     6961 agcacacttg atgtcctgtc tggactcaat ctagccatgc taatagaagc agtctttgct
     7021 aggcaagagc agcttgatct agaacaaatt gtcgctaagc tattaaccac agccaaggaa
     7081 gggatcagta attggaaatc cctctctggt gaggctgagg aagcagacct tgatgaagga
     7141 gggatttaat gactagacag atcaaagagg ttacccttga gcctctcata caagcagagg
     7201 tctatagcca gcagccatat ctaacaaaag ctgatattga ggcagctatt ttattagccc
     7261 ttaagcaaat ccgattaaac atggattatt ttggtactga tttccctagg ccagccacta
     7321 aggacaattg ctacccaatt atggataata ccgagtggac caatggcttt tggaccggct
     7381 gcctatggct ggcctacgaa tacactggta atgacactat caagtcacta gcacaggcaa
     7441 atgacctgtc cttcttagaa cgcgtcacca aagacattga gcttgaccat catgatttag
     7501 gatttcttta ttcaccctct tgcatggctg agtggaagct tttaaaaaca cctgaagcca
     7561 gacaggcagc cttaaaggca gcagataaat tgattgagcg ctatcaggaa aaaggcggct
     7621 ttattcaagc ctggggacaa ctcgggaaag cagaagatta ccgcttaatt attgattgtc
     7681 ttttaaatat ccagctactc ttttttgcca gtcaagaaac aggagatgac aggtatcgtc
     7741 aaatggctat caatcacttt tatgcctcag ccaacaatgt gattcgtgat gacgcctctg
     7801 cttatcatac cttctacttt gaccctgaaa caggtgatcc aatcaaagga gttacacgcc
     7861 aaggctacag tgatgactcc gcctgggcca gaggacaagc ttggggaatc tatggaattc
     7921 ccttgaccta tcgcttcttg aaggatccac agctaattgc cttatttaaa ggaatgacgc
     7981 actatttcct caatcgcttg cccaaggatc aggtatccta ttgggatttg atctttgaaa
     8041 atggcagtgg tcagtctaag gacagctccg caactgctat tgctgtttgt ggtattcacg
     8101 agatgttaaa acatttacca gagaatgatc ctgacaagaa agcttatcaa gctgccatgc
     8161 actgtatgct cagatcatta attgatagct atgccaacaa ggacatcaag cctggtgctc
     8221 cacttttacg tcatggcgtt tactcttggc actctggcaa gggcgttgat gagggaaata
     8281 tctggggaga ttactactat ttagaagccc tgctgcgctt ttacaaggac tggacccctt
     8341 attggtaggc tgatagcatt tagcctacaa agactattgt taaaggagat attatgacac
     8401 caccaaacat tatcatgacc agagttgatg agcgtttgat tcatggtcaa ggccagctat
     8461 ggatcaaatt tttaaattgc aacactgtca ttgtggctaa tgatgccgtt gctgaagaca
     8521 aaatccaaca gtctctgatg aaacctgtcg ttccatcaag cattgccatg cgcttttttt
     8581 ccattcaaaa ggtgattgac gtgattcaca aagcaagccc tgctcagaca atctttattg
     8641 ttgttaagga tttagaagac atcaagcgct tggttgaagg aggggtgccc attaaagagg
     8701 tcaatcttgg aaacattcat aaaacagacg ataaaatcgc cattacccaa ttcatttcgc
     8761 taggcgacaa ggacaaggct attattcgga cattgactca cgatcatcat attgtcttta
     8821 acactaaaac aactccagct ggcaatggtg cctctgaggt taatatttta gattatattt
     8881 aagaaaggaa attgatatgg atatcaattt gttacaagca cttttaatcg gtctttggac
     8941 agccttttgt ttcagcggaa tgttacttgg tatctacacc aatcgctgta tcattctgtc
     9001 ttttggtgtc ggcattatct tgggggactt gccaacagca cttagcatgg gagctatatc
     9061 tgaattagct tatatgggat ttggtgtcgg tgctggtggt actgtgccac ccaacccaat
     9121 cggacctggt atctttggta ccttgatggc tattaccagt gctggtaaag ttactccgga
     9181 agctgcctta gctctttcga caccaattgc cgttgctatt caatttcttc aaacctttac
     9241 ctatacagct tttgctggtg ctcctgaaac agctaaaaaa cagcttcaaa aagggaatat
     9301 taaaggcttt acatttgccg ccaatggtac catctgggct tttgctgtga ttggcttagg
     9361 acttggttta ttaggcgcct tgtcaatgga tactttactt catttggttg attatatccc
     9421 acctgtcctc ctaaatggat taaccgttgc tggtaaaatg cttcctgcta tcggttttgc
     9481 tatgattcta tctgttatgg ctaaaaaaga gctgattcct tttgtcttaa ttggttatgt
     9541 ctgtgcagct tacctgcaaa ttccaaccat cggtattgcc atcataggca ttatcttcgc
     9601 cctaaatgaa tactacaaca aaccaaagca tgcaacaaca gctgaacaag gaggtcaaca
     9661 agatgactgg atctaataag ctcacaaagc gtgattatct gaaaactgct cttagagcct
     9721 ttttcctgca aaatggcttt aactatagca attatcaagg aataggctat gccaatgtcg
     9781 tttacccagc cctaaaaaag cattttggca atgacaaaac aggcctttac aaagcactag
     9841 agaacaattg tgcattttac aatacaaacc ctcatttcct accttttatc accagcctac
     9901 acctggtcat gctagaaaat aatcggcctg aagaagaaac ccgcaatatc aagatggcac
     9961 tcatgggacc tctagcaggc atcggggata cccttacgca attttgttta gcaccactct
    10021 tttcgaccat tgctgcttcc ttagcaagtg acggcctgat tttggggcca attctctttt
    10081 tcctagccat gaatattatt ctaacagcta ttaaaattgg ctctggactc tatggctaca
    10141 aggtggggac aagctttatt gataaattaa gcgaacaaat ggcaattgta tctcgcatgg
    10201 caaatattgt cggagttaca gtgattgctg gtctagctgc tacttctgtt aagatatctg
    10261 ttcccatcac atttgcagca ggcaaggtcg acgctgcaaa tgcagcccaa aaatttgtga
    10321 ccattcaggg aatgctggat aagattgcac cagctcttct gccagccctc ttcactctct
    10381 tgatgtatta cctcattaaa acgaaaaaat ggacaaccta taaattagtt attctaacag
    10441 ttattattgg tattgttggc agctggttag gggtgttagc ctagcagtct tagagattct
    10501 gttaatcagt attggagggt ctccattagc gatgagcagg tctcttttct attgggcaaa
    10561 gctaagcatt gacaccatca actctcgtag cctcagtcag gtcttttgcc ctgtagagcc
    10621 tttaagcaca agcctttact gctagctgtg atgaaggcgt cctccttcta ctggcttctg
    10681 gcacaattaa tcctttatat ctctacaagc acatgattta gcggctgatt gcgcgccaat
    10741 cttacagaag gtcgcaactt aagaaagagt aggatcattt ttgacctctt caaaggtcat
    10801 attcttggac tgaaatatta aaacaattac cattccatat gttataataa aactactaat
    10861 gatgacaaaa aggggtctat gcaatgcagc gcaaagtaac catcaatgat attgctgact
    10921 tagctaaaac ttcaaaaaca actgtttctt tctacctcaa cggtcgattt gataaaatgt
    10981 ctcaggagac aaaaagccgg atcaaggagg ctattgaagc caccaactac aagcctagca
    11041 ttgcagctcg cagtctcaat gccaaggcta ccaaattgat cggtgtggtt atcggtgaca
    11101 tcaccaatag cttttccaac cagattgtca aaggtattga aagcaaggcg caagaatttg
    11161 gttatcagat tatcatcggc aacagcaact atgatccttc acgtgaggac gaattgattg
    11221 aaaaaatgct taacctaggt gtagatggtt ttatcattca accaacctct aactttagaa
    11281 agtattcacg catcatcgaa gtgaaaaaaa agcgcatggt tttctttgac agtcagctct
    11341 atgagcatcg tacaaactgg gtcaagacca acaattatga cgctgtttat gacaccattc
    11401 agcaatgcat caccaaaggc tatcaaagct ttatcatggt tactggcaat cctaatttgc
    11461 tgagcacacg catcgagcgt gcctctggtt ttattgatgt tttagaggct aaccagctcc
    11521 agtatcgtca aatgatcatc gatgaaaacc aaaccagctc tcaagaaatt gctcagtttc
    11581 tacaaggcgc atttgataag gaacgtcaca atctggtatt tgtcccaaac tgctgggctc
    11641 tgcctaaggt ttttactgcc atgaaggcac taaaggtatc attgcccgaa actggtctag
    11701 ttggctttga taacatcgaa tggactcgct tgtcatcacc aagtattacc actattatcc
    11761 agcctgctta cgaagaaggg gagcaagcaa ccagcatttt gattgatgat atcgaagggc
    11821 atagcaagga agccaagcaa caaatttttg attgtcaggt taattggcaa gaatcaacct
    11881 tctaacagga ttttttcgcc ttctagacct taaaaaatca gccattctaa taacgatgac
    11941 aaagtaacac gaggcttaac gcttgtttgc tagcatcaga aaaaacacat aaatcagcct
    12001 gaactacccg gttgatgaaa caataaacca ttaagcaacg gtcttattcc tcataccaag
    12061 aggagcaagg ccgttttgac gtttttgaca atggtcgtta ttgtaaacgt aacggtagtg
    12121 tattactgac aggctcttca aaaaagctgt cgtccttagg tcatacgagg ccttctttta
    12181 caagcgactg ctacttcttc actactagtg tgatctttta gccaatttct gagaacatca
    12241 tcagtaaaat ctcgcacctg ccaataatgg caagcaagct tttttgacca gcaagttaat
    12301 catgtatcac ttgtgacttc aactcttaac tgtttgtcct ttcaagtcta ctataagagg
    12361 aatgaattcc caaaaagatt catcagttgc tattatttag gtaagagcta taagcacaat
    12421 ggctattatc ctgtgatata ataaaagaca taagggttat aaaggagaaa ttgtatgagt
    12481 gataccatta catcaagccc tgtggctgct tctgctgcta ttagtgaatt ggtaggtgta
    12541 gacaccagta gggttcacca acagtccgtt gcatttagtg tgaccaaggg tattgcaggt
    12601 atggaaaagg gacgtcaggt ctctaatcaa ctgctgcagg ctgtcagcga ctttagtcag
    12661 gcagtcctta ttcaggctaa taaatttcct cagcttgcgg ccaaattaga gaaaagagac
    12721 ctagaggaag caacaagata ggggaataag tcatgatcaa agaagaatct gaagaaaaat
    12781 ttcttgccct aacccgacag atcaatgagc tggagtggct agaggaggat cttttgtcga
    12841 tgaaacgacg gcatgaacaa gcagtctcgg agattcaagc agactgtcag cacctctctt
    12901 ttgcccttga gtccctattg aaccatatgc ctgaggacta agctggaaag tacgcagagc
    12961 aagaggccaa tgaccacttg atcagacaaa tggatcgcta tgttgatgag catctggatc
    13021 acgtgtcaat ctatacgatg ggggttcgtc gtagactaga gagggacaaa gaagagctta
    13081 tcggtgaaag gagccgttta cgatgggagt gacctacagt gcagcagagt caaaggcctt
    13141 gattcaagcc atgacaaaca atatccaaat agccaatgaa ataacggaca ggttatcaag
    13201 tggttgcgac catctcattg ctagtctgga ttcgggagag ctacagggag cagcctatac
    13261 agcaggtagg ggacttttta cagcgatcat cattccctct atcaaaaagc tacaagcagc
    13321 gattgatgct atccaagtgg agttgaccac ctatcaaagg gcagatgctc agattgccag
    13381 atacggaacc ctggatcgtg atcacttaac cgagctgaag aggctaagag aacggcaagt
    13441 gcaagtgatc caagcacaga ttgatgaaaa cgaatcgttt atgaagcagg tcagtagtct
    13501 tttaaccgga gactatggca ccctttggtc tgatacctct acactatacc atgccaaaaa
    13561 ccagctggaa atagggattc gagatgttac gaccaaattg gaaagccttg aatggtttct
    13621 aactcaaacc tcagactgct ttagggacag cttagttatt ttgcggttag ccattcaggg
    13681 cgcaacacag ctcagtcagg tcttcatgag cagcgacggc agctactcga ctgctggcct
    13741 agatatgagc tgggtgacta gcctgaagaa tcaaaagatt agccctgtca atgcctcaaa
    13801 gtacactcaa aaccattatc acaacatact gactcagacc attaaaacca tcaaaagcag
    13861 ctctgaaagg ccactacaaa aatcagagcg acttgtagct gcctatgagg attacctcta
    13921 ttttctcaat aaaacagcct ttgatgacta ttggaaggcg agaagcaatt atgatggaga
    13981 gtgagacctt aaaaataata aatatgcaaa ggaaattgag gaagacctag ggaaaaaatt
    14041 acaatcgtcg ggtattaatt ttcgtttgat tgtcaacaag atgggagatg atatcctatc
    14101 agtgaatgtc aatgctccct acctttcaca ggtagctgga agtcaattaa gtgctgcaat
    14161 acttgacaac aaacaatttt atgaccttgt caatacgggt cagcccttgg atttgaagtc
    14221 aaggacctat catggccata actattctgt ctggtcaaga cagtgggaat cagaattgcc
    14281 aggcgactat gctggcaact acctctatgg ttatgttggt acaggctttt tagatgcttc
    14341 agggacttat ttaaaaacgg cggctgagat tgcccaggtc ttttctgata aggatatacc
    14401 aaagtggtta aagaacttat catcaggtca ctatggagac aatgagggtg atactcaaat
    14461 gatccaagca ggtatagatg gttatatgaa aaggaagaag tcaaaatgaa gcgaaaaatc
    14521 ctgttattaa tgatgttgct ggtaggtgtt ttcatcttct ccaaacgcta tgagctttac
    14581 tatttttttc aaggaaaaga atatctaagg ccaaatgaga gtatagagct tgcggtgaga
    14641 ccaaagtatg aacaaataga atattcctct gacctatacc tagaaagcga cgaaaaagtg
    14701 ctactgaagc tagaaggtcg tgatatatgg tctgaatata tttatagacg gacagacagc
    14761 tatcttagta agataggata tcggtattct ataacagaac aggttattga aaaatacgat
    14821 tccactaagg ataatggtgt agttattgta gaagctggac acaagggagc tactattgat
    14881 ggagatggcc tcatcgttcc cttgaagggg aagagaaaat atagtgtgac agaagatcat
    14941 gactatagta tcaccattac caacctgtcc gatcagccgg ttgcttttag agcaatagta
    15001 gcagataggt agtatgtgcg catgaactgc tttaggtttt tctgttattg attttagatt
    15061 tttgttaggc atagaaaagc tccccttata gcttctagtg atggtttgtt gggtcac
//
LOCUS       DARYUW010000048        15097 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYUW010000048 DARYUW010000000
VERSION     DARYUW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15097
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(220..1320)
                     /locus_tag="TVW11_001490"
     CDS             complement(220..1320)
                     /locus_tag="TVW11_001490"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1365577.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TVW11_001491"
     CDS             complement(1317..1673)
                     /locus_tag="TVW11_001491"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1365578.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TVW11_001492"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TVW11_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1365579.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TVW11_001493"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TVW11_001493"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1365580.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TVW11_001494"
     CDS             complement(5753..6637)
                     /locus_tag="TVW11_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1365581.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TVW11_001495"
     CDS             complement(6994..10050)
                     /locus_tag="TVW11_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1365582.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEEHWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYDSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGLYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TVW11_001496"
     CDS             complement(10279..12162)
                     /locus_tag="TVW11_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1365583.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TVW11_001497"
     CDS             12439..13878
                     /locus_tag="TVW11_001497"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1365584.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TVW11_001498"
     CDS             13883..14848
                     /locus_tag="TVW11_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1365585.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
BASE COUNT         4307 a         3767 c         2859 g         4164 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta aagtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgtcgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaatgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtga
//
LOCUS       DARYUW010000049        14738 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYUW010000049 DARYUW010000000
VERSION     DARYUW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14738
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(118..1377)
                     /locus_tag="TVW11_001499"
     CDS             complement(118..1377)
                     /locus_tag="TVW11_001499"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1365586.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(1693..2898)
                     /locus_tag="TVW11_001500"
     CDS             complement(1693..2898)
                     /locus_tag="TVW11_001500"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1365587.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(3231..5450)
                     /locus_tag="TVW11_001501"
     CDS             complement(3231..5450)
                     /locus_tag="TVW11_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1365588.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            5977..6918
                     /locus_tag="TVW11_001502"
     CDS             5977..6918
                     /locus_tag="TVW11_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1365589.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(6893..7096)
                     /locus_tag="TVW11_001503"
     CDS             complement(6893..7096)
                     /locus_tag="TVW11_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1365590.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(7477..9153)
                     /gene="dnaX"
                     /locus_tag="TVW11_001504"
     CDS             complement(7477..9153)
                     /gene="dnaX"
                     /locus_tag="TVW11_001504"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1365591.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(9153..9650)
                     /locus_tag="TVW11_001505"
     CDS             complement(9153..9650)
                     /locus_tag="TVW11_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1365592.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            9830..10600
                     /locus_tag="TVW11_001506"
     CDS             9830..10600
                     /locus_tag="TVW11_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1365593.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(10782..11054)
                     /locus_tag="TVW11_001507"
     CDS             complement(10782..11054)
                     /locus_tag="TVW11_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1365594.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(11077..11703)
                     /gene="udk"
                     /locus_tag="TVW11_001508"
     CDS             complement(11077..11703)
                     /gene="udk"
                     /locus_tag="TVW11_001508"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1365595.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            11799..12893
                     /locus_tag="TVW11_001509"
     CDS             11799..12893
                     /locus_tag="TVW11_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1365596.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(13158..14444)
                     /locus_tag="TVW11_001510"
     CDS             complement(13158..14444)
                     /locus_tag="TVW11_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1365597.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
BASE COUNT         4293 a         3425 c         2814 g         4206 t
ORIGIN      
        1 agacaggggg ttcttaaaaa tcaaaagccc ctaaaaccac tctcatacca agcagtctta
       61 ggagctctaa gcattcatgt caggtgataa tcattaggct atgaaagcct tcagttctta
      121 atcctcaata agctgaatat cagcccctaa ggctgttagc ttatcaataa tgttagcata
      181 gccacgtaaa ataaactcaa tattgctaat ctcggtttta ccctgagcca ttagacctgc
      241 aatcaccaaa gcagcaccag cccgcaaatc agttgcctta acctgtgccc cactgaggcg
      301 attagagcca tgataaacaa tttggctgcc aagaatggca atatctgctc ccatacgagc
      361 aagctctggc acatggttga cacgcttttc atatatcgta tcaatgatac taccacgacc
      421 ctcagtcctt aaaagcagag gagtcaaagg ctgctgtagg tcagtggcaa agcctggata
      481 gggagaggtt ttaatagtga ctgctttcaa ggcttcctgc ttttccacaa aaatagaatc
      541 ctcttcaacc gtcattctca cacccatttc ctctagctta gcaataaagc tctctaagtg
      601 ctcgtaaagg acattggtaa tccttacccc actaccaaca gcggctgcca aggcaatata
      661 ggtaccagcc tcaatgcgat ctgggatcac ctgatgtctg gtgccatgaa gcctttcaac
      721 tccctcaatc gtaatcacat cagtacctgc accacgaata tgcgccccca tgttatttaa
      781 cagtgtcgca acgtcaataa tctcaggctc tctagctgca ttttcaataa tggtcttacc
      841 ctttgccttt gtcgcagcaa tcatagtatt aatggtagcg cctacactga tagtatccat
      901 gtagatatga gcgccatgaa gctgctgagc ctctgtcatc aggtgcatgc ttgctccctc
      961 ataagatatc tgggccccca ttgcttcaaa agccttcaga tgaagatcaa taggcctagg
     1021 gcctaagtca cagccacccg gcaagcccac aaccgcctgc ccaaagcgtc ccaatagact
     1081 gccataaaaa tagtaagagg ctcttaggct gttaatttta ccataaggca taggaatatc
     1141 ttgaacccct ctggggtcaa tctccaaggt atccccctga taggtcacca tagctcccat
     1201 gagcttcatg atttcaataa gactgtcaac atcactaata gctggtaccc catctaaagt
     1261 gacaacatcg tctgccaaaa taatcgcagg aatgagagct acaacgctat ttttagcgcc
     1321 tgaaactgcc acctctccgg ataaggcttt tccaccatta ataataattt ttcgcatact
     1381 ttcaaaactt tctgatacta gaattcaacc tttttatttt atcacaaata gcggtctatt
     1441 acaatcacct catcaccagc tgctgcaaca ggcttaacaa cctgcctctt gatcactttt
     1501 cataacaggt ttttgagaag ccagactctt atctggatct ttcttctgct gcgcaggcct
     1561 ttttgtcttt catagccgcc aagcctgaca agttttgctg gactaaaaaa gctcccaacc
     1621 agcagcacag ccgctagctc aggagctatt atacctttaa gtcaatcatc aactaaccgg
     1681 cgctcaatct gcttaagcac cctctgacag tgctgccacc gcttctgtca atggagatac
     1741 cttgtccaat tgttcccaag gcaggtcaat gtctgttcgc cccatgtgcc cataggctgc
     1801 tgtctgccta tagattggac gcttgagatc aagcatctta atgatccctg ctgggcgcag
     1861 gtcaaagacc tgacgaacag ccgcttccaa aatactttct gacactgttg atgtcccaaa
     1921 ggtatccaca cgaactgaaa ctggctgtgc aaccccgata gcataggcta attgaacctc
     1981 tgctttactt gcaagccctg ctgccacaag gtttttggca atataacgag ctgcataaga
     2041 ggctgagcgg tcaaccttag ttgcgtcttt accagagaag gcaccaccac catgacgcgc
     2101 atagccacca taggtgtcaa caatgatctt acgaccagtc aagccagaat ctccctgagg
     2161 accaccaata acaaaacgcc cagtcggatt gataaggaat cttgtcttct catctagata
     2221 atgggctgga ataacagcct taatcacctg ctcaatcata tcttgacgaa tctggtcatt
     2281 gcttacttct ggatcatgct gggttgatat aacaactgta tcaacacgaa caggcttatc
     2341 atgttcatca tattcgaccg taacctgtga tttagcgtct ggacgcaaat agctgatctc
     2401 acctgatttt cgcagtgtcg ccaaacggcg tacaagctgg tgagataagg aaatcggcag
     2461 tggcattagt tctggtgtct catcaattgc aaagccaaac attagcccct gatccccagc
     2521 accaatcgca ttgaaatcat cgctttgtcc ttcacgtgct tcaagtgctt cattaacgcc
     2581 ttgagcaata tctggtgact gctcaaccag agatggatga acacccactg attctgctga
     2641 aaagccatat tctgcctcag tatagccaat ctcagcgatg gtatcacgaa ccacacgatt
     2701 aatatccaca taggcagttg ttgaaatttc tccaaaaacg tggaccgagc ctgtgtaaac
     2761 gcaggtctct gcagcaacgt gtgcctctgg atccttggct aaaatagcat ctaaaatagc
     2821 atctgaaatt tggtctgcaa tcttatctgg atgcccttca gatactgatt cagacgtgaa
     2881 aagtttacgt tctgacataa aaatgtcccc ccttaaaaag aatgataccc accagcacac
     2941 atgccagata ggattttcct agcctcactc atcaagccag ccgccaatac aaaaggactg
     3001 tatccaagct agcctatgac taacgcttag cgagttacaa agtaccggct tttagactgc
     3061 tatcctcaga taacaaagcc gtcttatcgg gacttaataa cttatctatt ataccacttt
     3121 tagcgggatt tgtaagagct ccatcagctt ttttctcaaa ataagaaaag gaataccgct
     3181 acaggcgtat tcctcctctt aatgtcgtga taatcagcgc aagctatcga ttaaccatgg
     3241 tggtgctcat cgtgatcatg atgctcatgg tcatgcttat ctgctgcctc ttgatcagta
     3301 tcagccggct tatgctcgtc ttcaacagct tctgctggtg tggcattatt tagactacca
     3361 ccctctgctg ccttgaagtt cttgataatt ccttgtggga attgtccgct ttcagcagct
     3421 agctcctcag ctgggaagtg gttaccatca gcctgaatgt atttcagggt ttggttaggc
     3481 tccttcaagg ccaaggtgtt aatcttgtta cgattaacat taattgcttc tagggcgaga
     3541 taattgttga caccctcaaa attagtcagc tggttctctt caaggttaag agactgtaat
     3601 gagctttgtg tacctggtaa ggccaagcta ttaatcatgt tctggttagc tgatagctga
     3661 atcaggctct tattgtgctc aagacctgtc aagctgttaa gcttgttttg gtcaaccact
     3721 agctgctcta atgccggtag atccttgaca aagctaaggc tttgtaaatt aacctccttg
     3781 gcagtgattt ccttgagagc agaggatttt aaggttgaca aatcaaggtc agggttgttt
     3841 gacacaaaga gtttggtcaa ttgtcccttg tttgacaagg cactcaagtc cttaatctga
     3901 ttgtgctcta ggctgacagc gactagcttt tgagcatttg ccaaggcaga aagatctgta
     3961 atcttgttaa agtcaaggtt aacggactct aggtttggca attctttcaa aatagaaata
     4021 tctgtgatat catttcctgc tgccgaaatt accttgtaat gcggaaaggc tttaaggaag
     4081 ctcaaatcag aaacaccatt ttgagaaata tcaattcctt caagcgttgg caggttcttc
     4141 aagaaatcat aatttttaat gccggtctgt gtcatccaca attgtttgag gttcttgaac
     4201 tggtagactg gggtaatatc agtgattggg gtaaagccaa tacctaaaat ctgtatatta
     4261 ggcatcaggt ttaaacctgc ccgcttaaga ggatccttaa tctcaccgat attgaggtat
     4321 tcaacagtcg ccaaccatgc cttcattttc tctaggtctc gctctcttga tggaaactca
     4381 gttggtgcat ttgcatggat aatggacgaa atcacttcct catcaaagcc aagctttctc
     4441 agagttgcca taccgattct atccttagca tgcggatcta ctgcatgagg atcaaaaggt
     4501 tttgataaat caatatcgtc aatataggtt gcatgacgat ggtcaccatg tggatagtca
     4561 agaatgatac cttcttctgt atgctccaca cgaatgctgt cctcaggaat atttaatgac
     4621 ttagccaaat atgctttttt caaagcaatc gttttctcaa gatcactttg tggcttagct
     4681 ggtgcttctt cctttggctg ttcgattaaa tgcttccact tgctgttacg caagctttca
     4741 taagtgacta aatgattgtg gccattgtga tcaacaatca atccatatga tgttcgaccg
     4801 acaatacctg tcccgtcaaa caagaagcca tcacttgttg ggtaatcaac acctgcaaat
     4861 tttccagacg gtgatgatgg agctgatagt ggcacatggt taggcactgg ataagctacc
     4921 tgaccaccta gtgagctttt taggatatag tggtaatgat caccatgacg gacaatatag
     4981 cccaaggcgt cctcagctac aatatcagct gggttaaaca catagtgatg gtgcgggtca
     5041 ttagcactag tatggtgatg acctgatgct gccttggtct gctcaggctt gtttaggtca
     5101 gcgtcctttg gaatcaggta ctcaaacttg ctgcccttga gatctgcata aaaaataaaa
     5161 tgcgaatgcc cattatgctc aacaacaata ccgttttctg ttctagataa gatttttgaa
     5221 tccttggtca agataaaacc gtcatcagtt ggaaagtcaa tccccgctac tcccttacgg
     5281 tcttttcttg tttgcttaac ctttttagac tgtttctttt tggtcgcttt tttagctgtc
     5341 tgttttgtct taggctgatt tgttggctgc tttgtcgact gacaagctgt cagggtcagg
     5401 tgacaagcca taaacaggct agccattagc attaattttt tacttttcat ctttcctcca
     5461 taaattaact ggttaaataa gatattaact agttaaatat accaaaaaaa caaataattt
     5521 caactgtttt cttattttta attcattctc attcaacaat catagtagct tggctaggtt
     5581 ggcagaaaaa tgagcctctc ctactctcat caaataaaca gatagcctta atgatggctg
     5641 agataacagc atacaaagtc gttaaagtca cttgtaagaa aaagaaggac atatcttacc
     5701 accactatct tgctcatcaa agccctacgg ctttcagaca aaatcttcat aacagcggaa
     5761 aggctgatga agcagctcag acaaaaagag caagctcctt aacgtcaagg atcagagatc
     5821 agcacaaaaa taacagcagg ctacattaag aactgcaatt ccttgaaata gaattgcttt
     5881 tttacaaaaa aatcgtctcc ctagactgtt ccatcatctc acgtcatttg tattatttgc
     5941 tcttgaaatc cagtcatttt atactatact agaattatga agacatctga aaaaatttac
     6001 caattactag cttgcagcga cgactatgtc agtggagaat acttggcaga gcagctcaag
     6061 ctttctagaa cctctgtctg gaaatccatc aaaagccttg aaagtcaagg ccttcacatt
     6121 gaatccctca agcataaggg ctatcgcctt attcaaggag atatattgct gccagagctc
     6181 atcagccaag agctcaacat gcctttatct tatcatgaga aaagccagtc aacacagcta
     6241 gacgccaagc aaggaatcga gctaaagcat actgctccta ggctctatct cgctccaagt
     6301 cagtatgcgg ccaaggggcg gcttaatcgc caattctttg cgtcacctca tggcggcatt
     6361 tacatgtcct tgcatctcaa gccaaatgtt ccttacgcag acatgcctcc ttacaccatg
     6421 atggtggcct ctagtattgt taaggctatt tcaagattga ccggtattga cacccaaatc
     6481 aaatgggtca atgatattta ccttggccat aaaaaaatcg ccggtatcct gactgaggcc
     6541 attacctctg tggaaacagg cgtcattact gatgtgatta ttggcgtagg gcttaacttt
     6601 tttgtaaccg aattttctga aaacctcaaa gaacgagcag gctctctttt tagcaacaag
     6661 cctagtatta ctcgaaatgc cctaatcatt gacatttgga agctctttac cacaatacca
     6721 atcaaggacc atattaaggt ctacaaagaa aaatcacttg tccttcaaaa acaagtgagc
     6781 ttccaagaaa atgatcgtca aaaaacagca actgccattg acctgactga tgaaggacac
     6841 ctcatcgttc aattagacaa tggtcagcta caggtcttaa ggagcggcga aattagtctt
     6901 tcttcctggg gggattaaca gcattaatga tgtttttggt aaattggtca atagcataag
     6961 cacgccttaa atctctaaag agcaaaagac cccaaaacag agcaaaaata taatcgcctg
     7021 aaaataataa atcgctgaaa aaataagctt caaaggcaca aatgaatgcc ataaacataa
     7081 attgtcgaat agtcatacta ctattatacc aagaaaacta aatttccact aacgattttc
     7141 acgcagcttg aagaaaaagg cagttagcct gcttcaagct tttttgctgc tctttgatag
     7201 cctgtaacag tcaaataaaa aagagctcac tctaaaaacg acgccaaaag ccagcttgat
     7261 tgctaggctt gtagtcaatt gtctcaaatc agtgaatcac taagccttat aagaactcag
     7321 tcattgggtc acaatgacac ctagctctaa gcagcaaaaa agagaaccac accggtcctc
     7381 tctagcttgg cttgtcagct atctattagt gctgacaatg agccctgtca tctccttatt
     7441 ctagacaatt gatacactac caatcatcag ctagcgctaa tcctctatga gatgaatctt
     7501 atcagttaaa aagtcaaacc cctcaggcat gtcaaaggtc gcttgctcag actctttggc
     7561 tgtctctttt ttggttttga tggtcatggc aaactccgag cgaatatggt ggaagtctgc
     7621 ctttggtact gccaagatat gaggagaaaa ccctgctgcc ttactcatga tattcccaaa
     7681 catatcattc aaatcctgac gcttcatggc ctgctcagcg ttaaaggcgg cctcaaaggc
     7741 caaaatagca ttttcactat tggctaaaac aggctccgag cctagtaaca aagctcgatc
     7801 ctgtgcagaa atactatcta aaatctcatt ccaagcactt tttagcgctt ctaaatattg
     7861 tcgtgactgc tggctatctt gaacagtttc ctccatgatt ttcaatatct tttcccgatc
     7921 aaccttgtag gtaaaggcct ttggcttgat ggaatgagct ggtgtagcct gcgcagttag
     7981 acccttttga gcctgtagct gtgatatcgt ctccctcagc tgactaatct catgcttcaa
     8041 gtcatcaaca tcagctagca ggctagacgg tatcgcagtg tctgctgctt gtccttgctc
     8101 tgccagctga atggtcatca tttcagcgta gattctagga tgggttcctt ttttgatctc
     8161 aggcaaatgc ttggttactg tagcaatcat tgtaaaaagc tgatcaaaag acactgcaag
     8221 gttatcatca aaaagagctg actgcctgtg atgatcacca cctgatttca caatgagcag
     8281 gtctctaaaa taggttagca gatccgttgc aaagcgactc atgctcttgc cactatcata
     8341 aattgtttct agattagcta aggcctgact tgttttttgc ctgatgagat gctgaacgta
     8401 gtcgtctaag gccgaaatag aaatagagcc tgtgatttct tctgcaatag caagcgtcac
     8461 tcgattgtca aaggataggc tcaaggcctg atctaaaatg gatagggcat cacgcatgcc
     8521 accttctgct cgtcttgcaa ttaaatgaag cgcctctatt tcataggcta tgccctcctt
     8581 gtccagtatc gccgccaaat gctcacaaat agctggctgc ttaatggctt taaattcaaa
     8641 tcgctggact ctagacaaaa tagtagctgg aatcttgtgt agttctgttg tggctaggat
     8701 aaaaaccaca ttgtcactcg gctcttcaag ggtctttagg agcgcattga aggcccctgt
     8761 tgatagcata tgcacctcat caataatata aaccttgtag gttgcccggc taggagcata
     8821 ggttgactta tctcgaatat cgcgaatttc atcaacacca ttattagagg cagcatcaat
     8881 ttcaatcacg tcctccaggc tgccagttgt aatatctcgg caaatatcac aatgattgca
     8941 gggctctccc ttgacctgat tagggcagtt cattgcctta gcaaaaattt tggctgcgct
     9001 ggttttacca gttcctcttg gacctgaaaa gaggtaagca tggcttatct tttctgactc
     9061 aacagcctgc tttaaggtgg tcgaaataac tgactgccca accatttcag caaaggtctg
     9121 gctacgatac ttccggtaaa gggcttgata cattaattct caactccaaa catgtcaaaa
     9181 cgaaaagatg tattttctag taataaggct acaaattgct ctaaatagtc ttgatctatc
     9241 tgatcataat cagcaacaag actggaatcc aaatccagaa caccaacaag cctgccagcc
     9301 ttaagcattg gcacaacaat ctcgctcatg gctgctgaat cacaggaaat gtaattagca
     9361 tgctttttga catcatcaac gatgatggtt tgaccagatt gagctgattc tccacatact
     9421 cccttgccaa gcttgatatg cacacaggaa acctttccct gaaagggacc aaggatcaat
     9481 tcttgaccat caaaaaggta aaagcctgca aaaacagaat gaggcagggt catttttaag
     9541 agggcactag cattagagag attggccaag gcattgcttt cattagaaaa taaggcttta
     9601 gcttgagcca ataatagctg ataatgttca atttttgtcg tcttattcat ggttcttatt
     9661 ataacatatc tgctactaat cgttaaacga tttccacagg aaaagaattt taatcagcct
     9721 ctctagaaaa gaaagagatt ttatgataaa atagtgagta atattaaaaa aataggagag
     9781 tcagatgccg ttgttgagat ataaaaagat tatcgctacg accttattta tgttattagt
     9841 gtttaatggt attgagtatg aatgtctaaa ccttgtcagt cccaaacaaa ccttttacca
     9901 atccgctgcc ttaatcctct caaccagcct actagggatc tatctgattc ccttttcact
     9961 ggctattgct tatctcaagc gcatctacca gataaggatc tcaaccctgc tattagctgg
    10021 gctaggcggt ctttatatta gtggcttttt agcctccttt ggcaatcagg ttttagagca
    10081 attttggatt agcctgataa agcccaatat tgccttagag gagtggacgg gagctttgac
    10141 agggcctttt gtggaagagc ctattaaggc ctttgcagct atgcttgtca tttatttgct
    10201 gccagctatt aatcttaagc aaaaattagt catcagtctc atttctggca tgggattcca
    10261 gctgactgag gacattagct atattgcaag tgcggctgat cggtccataa atgacatttt
    10321 gcctacaacg cttgccagga ttagcagctc accaaactct cattgggtct atactggtat
    10381 ttttacaatg ggagcatacc ttttaattaa aaaatctcaa ttattcccaa ggtctctgca
    10441 gattttctgg gtggtaagtc ctctagccct acattttata tggaactctc ctatctcaga
    10501 tttagctggt gtcgcagtta ttcatggaac aataacaacc cttatcttta tcagtctatt
    10561 caaaaaaatc catgccctag acgacagcat cgcctactag cgtcatagga cacgagcaac
    10621 caagcccagc cgcatttggg catgtgatgg ctcatatgca tatatagcta ctcacctctc
    10681 gcttaagcta taggcagcta aatacctatc acaatagcag aaaaaatgac taccagtctt
    10741 aaaagggcta gtagtcattt taagctaaaa acaagcactt cttacaggat ataccactga
    10801 tacagataat agcaaagcac aagggtcatc agtatcccca tataccatga aaggacaaaa
    10861 taccatttct tcgttttatg gttaaaataa tgcccagcta gataggctcc aatcccacca
    10921 cataagagtg acaacgttaa tagcattttc tcagaaagtc gccattgacc tttttgggct
    10981 ctgtgtttat cactgccata ggccgcaaag accacagcat tccaaccaaa aagcaagatt
    11041 aggcttggta gcatttgtct gtctccaatc acagcactac agctcaccta agatgctggc
    11101 aatctttgtg ttgatgagat caatagcaac cacattgcta accccttctg gaatgacaat
    11161 atcagcatag cgcttacttg gctcaataaa ttgatgatac atcggcttga caacgcttgt
    11221 gtactgctca ataatgctct caaggcttct gccacgctca accatatcac gctgaatacg
    11281 acggataatc cgaatgtcat catctgtatc aacaaaaagc ttgatatcca tcagctcacg
    11341 caaacgctcg tcctctaata ccagaatccc ctcaacaata atgacgtcct gaggctcttg
    11401 gcgaaaagtt ctgttgctgc gagtatgctc cttataatca tagattggaa tatcaacagg
    11461 ccggccagcc aagagttcct ttagctgctg aatcatgaaa tccgtatcaa aggctaacgg
    11521 gtgatcataa ttagtcttaa ccctttcctc aaagctgata tgtgattgat ccttgtaata
    11581 cgaatcatgc tgaatcatcg caattctcgc atttggaaag ctatttaaaa tggcacgaga
    11641 cacgctagtc ttaccaccac cagaaccacc agtcacacca ataataatgg gttttttaag
    11701 cattgtaaac tccaaatcta aaagtctttc ggtctatttt accaaatttg ccactataat
    11761 gctataatga agagaaaaca aaataaaagg atagatatat gataaccaac cttcccactc
    11821 aatggcagga aaagctggca aagcttggct ttactaatct caccccaatc caagagcagg
    11881 tctttcagcc cattgttgat ggcaaaagcc tattaggcat tagccccacc ggaacaggca
    11941 aaactctggc ctatttatgg ccaagccttc tcaggctaag ccctaaaaaa gcccagcagt
    12001 tgctgatttt agcacctaat actgagctag ctggacagct ttttgaggtt accaaggaat
    12061 gggcagagcc cttaggatta actgcgcagc tctttatttc cggaagcagc caaaaacgcc
    12121 agatcgaacg cctcaaaaaa ggcccagaaa tcattatcgg aacaccggga cgcatttttg
    12181 aattagtaag gcttaaaaaa atcaaaatga tggccatcaa taccatcatt ttagatgaat
    12241 acgacgacct actgagtgac tcccaatacc agtttgtcca aaaactctcc cattacgcgc
    12301 ctcgtgacca tcaaatgatc tacatgagtg ctactaacaa gatagagcaa gccagtctag
    12361 cggatcatac cttggtcatt gatctgtcta agcaagcatt gccttgcatt gagcactgct
    12421 acatgctggt tgacaaaagg catcggaccg atatcctacg taagctagca aatattcctg
    12481 actttcgtgg tctggtcttt tttaacagcc tgtcagacct aggtgctact gaagaacgcc
    12541 tgcaatatag tggagcttct gttgcttctc tagccagtga tgtgaatgtc aagcagcgaa
    12601 aggccatttt agaagccttt aaagagcaga gcatttcact gctgcttgcg acggacatag
    12661 tcgctcgtgg gattgatatt gaccagctag aatacgtcat taacgctgag gttccccgta
    12721 ataaagagca atatactcat agagctgggc gaaccggtcg tatgggacga tcagggattg
    12781 tcataactct tgtcagtcac cctgaagaca tcaagcgcct taaaaaattt accaaggtca
    12841 ctgagatgta cttgaagcat cagcaattat accaaaaaga aataagaggc tagctcaaag
    12901 gatataaacc taaaaagctt gcctccaagt atgatgtaaa gcaactaatc actatttctt
    12961 acccttgcta ctaaaaaaac gaacgtaaag tccttctgac atgaagtcaa aaccttacgt
    13021 tcgttttata ttatactgac accactggct ttattagtat agtagatact ggccatgctt
    13081 agccagacta gatactttct tgaagtgagc ccgccattta gtcatgctct agagccttac
    13141 ttgctttttc tgactgacta gcggctacca tatagctcag ataaggtcac acatttgtat
    13201 ccttccgctt ttaggtattc cataatactt ggcaaggcat ctacactggt ctggtgaata
    13261 tcgtgcatta gaacaacccc tccaggctgc aattgctgct tgacatttgc catgatagca
    13321 gcagtattac gattttccca atctctggta tcaactgtcc aaagcatttc cttaagaccc
    13381 gatgcccttc taacaatatc attagtagct ccataaggag gacgaagata gactgggcgt
    13441 tttccacagg ccttttcgat ggcttgattg gtcgtattga tctgtgtttg gatctgatca
    13501 acggttaggg tcgtcaaatc agggtgatcc caagaatgat tctcaacatc atgaccagca
    13561 gcactaacct tcttaaccaa agcctcatgg ccaacaacct tagaccccat cataaaaaag
    13621 gtccccttgg cctgatattt ggccaaaata tctaaaacct gcggtgtggt cacagggtct
    13681 ggaccatcat caaaggtcag agcgactagc ttttgtccct ctttttctgc ctcttttgcc
    13741 ttcttttcct ccaaatactc ttcataagca gtcttgtctg aaccctctag aaaatctgga
    13801 ttaatcacat caaacaggct tgcaagaggt attgacatat gaccaaataa aataagatta
    13861 cccgaatcaa tggcaaagcc atcgcttaat acctgatttt tttctatcat cgtatcagtg
    13921 ctcagcttga tctctttgcc tggataaagc ttgccaacct cttcctcgat gcgatctaag
    13981 cgaccagcaa ctagctcctc tagcttaaag gggctataat cctctttcac atggtaacga
    14041 ctaacagcct tttctgtagt cttttttaga ccaaataact gaggcttgta gaccgtcttg
    14101 tagataacca attgattgac ctgcttgata tgtgaagcct caagcttagg ctttaccatg
    14161 ataacagcct tgtcagtctg cttgccttga tacagagaca taggcagatt tgacacataa
    14221 aaatcgtcag ccttctcaat cggagacagg taataccaat cctgctttcc tttcttgaga
    14281 tacttgacct ttttgatctt tggactatcc ttagaagcag tctgttcgag cttaatgact
    14341 ctctgagtat cctgccctat tttccaagat ctaatgaagg taaacgcaac accgaccaac
    14401 aataaactta ataaaataat gagaatataa tttagctttt tcaatctcgt cctccaatta
    14461 ccctacaatt ttaacacaag atagttggaa aataaataaa aaaagttagg tttccttaac
    14521 ttttttcagt ccaaaataag ggcaaaaaag tgttttatgg tgcaggattt gcctgagtta
    14581 ttttcccttt atcacagcca tttgtcactg gataaggggc tagatattat acctaaagct
    14641 tctctttatt gctatcatta ttctgacatt cttaggcatg ctatttccct tgataggact
    14701 tgattgctgt ttctttagct tgtaaggatc tcctaaaa
//
LOCUS       DARYUW010000050        14340 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYUW010000050 DARYUW010000000
VERSION     DARYUW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14340
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            401..961
                     /gene="ahpC"
                     /locus_tag="TVW11_001511"
     CDS             401..961
                     /gene="ahpC"
                     /locus_tag="TVW11_001511"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1365598.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            982..2514
                     /gene="ahpF"
                     /locus_tag="TVW11_001512"
     CDS             982..2514
                     /gene="ahpF"
                     /locus_tag="TVW11_001512"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1365599.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            2975..3745
                     /gene="rpsB"
                     /locus_tag="TVW11_001513"
     CDS             2975..3745
                     /gene="rpsB"
                     /locus_tag="TVW11_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1365600.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            3913..4953
                     /locus_tag="TVW11_001514"
     CDS             3913..4953
                     /locus_tag="TVW11_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1365601.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(5153..7048)
                     /locus_tag="TVW11_001515"
     CDS             complement(5153..7048)
                     /locus_tag="TVW11_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1365602.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(7600..8532)
                     /locus_tag="TVW11_001516"
     CDS             complement(7600..8532)
                     /locus_tag="TVW11_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1365603.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(8529..9386)
                     /locus_tag="TVW11_001517"
     CDS             complement(8529..9386)
                     /locus_tag="TVW11_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1365604.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(9389..10732)
                     /locus_tag="TVW11_001518"
     CDS             complement(9389..10732)
                     /locus_tag="TVW11_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1365605.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(10745..11032)
                     /locus_tag="TVW11_001519"
     CDS             complement(10745..11032)
                     /locus_tag="TVW11_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1365606.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(11034..13076)
                     /locus_tag="TVW11_001520"
     CDS             complement(11034..13076)
                     /locus_tag="TVW11_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1365607.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            13599..14189
                     /locus_tag="TVW11_001521"
     CDS             13599..14189
                     /locus_tag="TVW11_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365608.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT         4439 a         3221 c         2806 g         3874 t
ORIGIN      
        1 aaccgacgat caagcttttg cagagccgtg ccttaccact tggctatacc gccataacaa
       61 gaactatttt accctagttg atagcattcg tcaagataaa aatagcagct attttttagc
      121 aggctgctcc ttttttcggt ttatgttatt ttttagagtt taaatcagaa aatcattttt
      181 aataatatta aaattatttc aaaaacttat tttcaagaat ctttgatatt atcagagttt
      241 tctattattt agaatagttt taaacagtgt gactaaattc acatatgaaa ttgttagaaa
      301 agaacatcaa aaaccttgat aaatctaggg tttacaagtg gacagataag atttcttagc
      361 ttataataca ggtatcaaat gtaaaaaagg aggacatgac atgtctttag taggaaagga
      421 aattgctgaa ttttcagccc aagcttttca caatggaaaa tttatcactg taactaatga
      481 ggatcttaaa gggaaatggg cagttgtttg cttctaccca gcagactttt cttttgtttg
      541 cccaacagag ctaggtgacc ttcaagagca atatgaaata ctaaaatctt taggtgttga
      601 ggtttattct gtatctactg atacacactt tgttcataag gcatggcacg atgattcaga
      661 tgttgtcgga acaatcactt acccaatgat tggtgaccca tcacatgcta tttcacaagc
      721 ctttgatgtt cttggtgagg atggacttgc tcaacgcggt actttcatta ttgatccaga
      781 tggtgttatc caaatgatgg aaatcaatgc tgatggtatc ggacgtgatg caagcagctt
      841 gattgataag attcgtgctg ctcagtacgt tcgtaagcac ccaggtgaag tatgcccagc
      901 caaatggaaa gaaggggctg aaacactaac acctagcctt gaccttgtcg gcaaaattta
      961 agcaggcaaa ggagaaaagc tatggcatta agtcctgata ttaaagagca gcttgctcaa
     1021 taccttaatc ttttggaatc tgacttagtc ctacaagctt atcttggtag tgacgatagc
     1081 tcacaaaagg tcaaggactt cattgaagaa attgctgcca tgtcagaccg tatcactgtt
     1141 gaggagacta ccctaacacg tcaaccaagc tttaagatta cccaaaaagg tcaagacagc
     1201 ggagtgatct ttgctggact gcctctaggt cacgagtttg cctcctttat ccttgctcta
     1261 ttacaggttt caggacgtgc accaaagatt gagcaggata ttattgaccg catcagggct
     1321 attgaccgtc ctttaagctt tgaaacctat gtcagcttaa cgtgtcataa ttgcccagat
     1381 gtggtccaag ccttgaacat tatggctgtt cttaataaga acatttcaca tactatggtt
     1441 gagggtggta tgttccaaga ggaagtcaag gcaaagggca tcatgtctgt gccaactgtc
     1501 tttttgaatg gagaagaatt cacctctggt cgcgccacta ttgagcagct gcttgagcaa
     1561 atcgcaggac ctctatctaa ggaggccttt gctgataaag gagtctatga cgtccttgtc
     1621 attggtggag gacctgcagg aaatagtgct gccatctatg ctgctcgtaa aggcttaaat
     1681 acaggtcttt tggctgagac ctttggtggt caagtcatgg aaactgtagg tatcgaaaac
     1741 atgataggaa ccctgtatac agagggacca aagcttatgg cccaggttga ggagcatact
     1801 aaatcctatg atgttgacat catcaaagcc cagctggcta cttcgattga gaaaaaagac
     1861 cttgttgagg ttactcttgc taatggcgct gtcttgaagg ctaaaacagc tattctagcg
     1921 cttggtgcaa aatggcgcag tatcaatgtt cctggcgaaa atgagtttaa aaataaagga
     1981 gtaacctact gcccacactg tgacggtcct ctctttgaag ataaaaacgt tgctgttatc
     2041 ggtggtggta actctggact tgaggctgca cttgatttag ctggcttagc taagcatgtc
     2101 tatgttcttg agttcttacc tgagcttaag gccgacaagg tgctacagga tcgcgctgct
     2161 aaaacagaca atatgactat tctaaaaaat gttgctacaa aggatattgt tggggacgat
     2221 catgtcacag ggcttaacta tatcgagcgt gacagcaatc aagaaaagca tcttgacctt
     2281 gaaggagtct ttgtacagat tggcttggtg ccaaatacag cttggctcaa agacagcggt
     2341 atcagcttaa ccgatcgtgg cgagattatt gttgataaat atggttcaac caatattcca
     2401 ggtatctttg ccgcaggcga ctgtacagat tcagcctaca aacaaattat tatttctatg
     2461 gggtcaggtg ctactgctgc tattggagca tttgattacc tgattcgtca gtaagttagc
     2521 aaaaaaccaa ggtaactgtt taccctggtt tttgcttttt agaggcctaa taaacagcaa
     2581 ggctgataga tcaagcattt ggggtacgcc aaatgcttga agaaacttat gttctctgat
     2641 atcttttcat gattcatgtg ttctttttca gaaagattga tagtaaaact aagctgcgct
     2701 tgaaaaatgg atcgtgtcaa aacgtcaaca tatcaaaaat gcattgaaaa catgcatatg
     2761 gttagaaaat aatggcatgc attttcctca tgcgtacgac gtgggtttta gtgtatttag
     2821 gcttgctatg actagctttt tttggtatac tgttgtagtt gtgcagacaa caaatactca
     2881 tcttagatcg attgtgattc tgttgccatc aggtggagtt gcaagccgac gtctaagaga
     2941 ggaaaaaaac atttctataa aggagaaact actcatggca gtaatttcaa tgaaacaact
     3001 tcttgaggct ggtgttcact ttggtcacca aactcgtcgc tggaacccta agatggctaa
     3061 atacatcttc acagagcgta acggtatcca cgttatcgac ttgcaacaaa ctgtaaaatt
     3121 agctgatcaa gcttacgagt ttgttcgtga tgcagcagct aatgacgctg ttatcttgtt
     3181 tgttggtact aaaaagcaag ctgctgaagc agttgctgac gaagctactc gtgcaggtca
     3241 atacttcatc aaccaccgct ggttgggtgg aactcttaca aactggggaa ctatccaaaa
     3301 gcgtatcgct cgtttgaaag aaatcaaacg catggaagaa gaaggaacct ttgaggttct
     3361 tcctaagaaa gaggttgcac ttcttaacaa gcaacgcgca cgtcttgaaa aattcttagg
     3421 tggtattgag gatatgcctc gtatcccaga tgtgatgtac gttgttgacc cacacaaaga
     3481 acaaatcgct gttaaagaag ctaagaagct tggtattcca gttgtggcaa tggttgatac
     3541 aaatgctgac ccagatgaca ttgatgtgat cattccagct aacgacgacg ctatccgcgc
     3601 tgtcaaatta atcactgcta aattggctga tgctgttatc gaaggccgtc aaggtgaaga
     3661 cgcagaggtt gcatttgaag ctgatactca agcagagtca atcgaagaaa tcgttgaggt
     3721 tgttgaaggt tcaaacgaag cttaagtcag gcttattgaa ctaggatagc ttcttgctat
     3781 tcataacatg gtctaacggg gcaaagcatt ccgctctatc tcgttatttt ttaagtaaga
     3841 aaacccagca ggtcaaaggc tctgctaaag cgagctttaa gaggaccgat tctaattttg
     3901 gaggaaataa aaatggcaga aattacagct aagcttgtaa aagaattgcg tgaaaaatct
     3961 ggtgccggcg ttatggacgc taaaaaagca cttgttgaaa cagatggcga catggaaaag
     4021 gctattgagc ttcttcgtga aaagggtatg gcaaaggccg ctaaaaaagc tgaccgcgtt
     4081 gctgctgaag gcttgacagg tgtttatgtt aatggtaacg ttgctgctgt tgttgaggtc
     4141 aatgctgaaa ctgacttcgt tgccaaaaac gctcaattcg ttgaattggt aaacgcaact
     4201 gcaaaggcta tcgcagaagg taagccagct aataacgacg aagcacttgc tcttatcatg
     4261 ccttctggtg aaacacttgc tgatgcttat gtcaatgcaa cagctacaat cggtgaaaaa
     4321 atctcattcc gtcgctttgc cctagttgaa aaaactgatg accaacactt tggcgcttac
     4381 caacacaatg gcggccgtat tggcgttatc actgttgttg aaggcggaga cgaagcactt
     4441 gccaagcaag tatcaatgca cgtcgcagct atgaagccaa ctgttttatc atacactgag
     4501 cttgacccac aatttatcaa ggacgagttg gcacaattga accacgctat tgagcttgac
     4561 aatgaatcac gtgcaatggt taacaagcca gcacttccat tcttgaaata tggttcaaag
     4621 gctcaattat cagctgacgt gattgcgcaa gctgaagaag acatcaaggc tgagcttgct
     4681 gctgaaggta agcctgaaaa gatctgggac aaaattatcc caggtaagat ggatcgcttc
     4741 atgcttgata acactaaggt tgaccaagcc tatactcttc ttgctcaggt ttacatcatg
     4801 gacgacagca aaacggttga agcatacctt gactcagtca atgctaaagc gattagcttt
     4861 gctcgctttg aagtcggtga aggtattgag aaaaaagcta acgactttga atcagaggtt
     4921 gctgctacaa tggcagctgc gcttaacaac tagtctaatc ataagtcata agattgagga
     4981 cagcttttaa gagctatctt caatcttttt ttacgcctaa aaaaagagct tttcgagcct
     5041 atccaacaca aaaagactaa gagaagcatg ccttcctcca caagctagac tatacgttct
     5101 aacgatagga gggccgtaca aagcctctta gtcttttttt aatgagcaat gattaccaaa
     5161 taatcacacg atcctctgga gcacgccaca ttggatcacc ttctttaatg ttaaattctt
     5221 ggtggaattc atcaaagttt gtcaaggtca cattagtacg ccattgacca ggtgcgtgga
     5281 cgtcaatact tgccatcatt tgcatgaatt cctcacgcgc cttcatacgc cagatggtgg
     5341 caaagttgat aaagaaatct ctggcagaaa aatctggctc tgactgagct gcctctaagg
     5401 cacaggcaac accacctagg tcagcaacat tttcagacac tgttaattta ccattgactt
     5461 tagcaccata ggagtcaagg ccatcaaatt gctctacaat tttatcggta cgctccttga
     5521 aggcggcata atcctcgtct gtccaccaat tctttaggct accatgctca tcaaaggaag
     5581 caccgttggt atcaaaggca tgcgaaattt catgagcaat aacagcaccg ataccaccat
     5641 aattagctga tgagctttga ctcaacgaat aaaacggcgc ctgcagaata gctgctggga
     5701 acacaatttg gttttgctgt gggtcataat aagcattaac catgttggca ggcatgtgcc
     5761 attcactacg atccacaggc ttattccact tgctccatga atgagcaatt gaaattttgg
     5821 ctaaattctg agcattttca acaagtgata gcttatcatc gatgaccttt ttagcatagg
     5881 tttctggtaa tttttccgga tagccaatgt gtggggtgat aacatttagc tttgtaatgg
     5941 ctttctcacg tgttgctggt gcaagccaat ccgcagtttc aagacgagat ttataaacct
     6001 caatcatctt agctaccttg tgttcaacat cagccttagc ctctggtgaa aatttttcac
     6061 cagcatacca aagcccaaga gcttgattaa atggtccttg tgctaagtaa taggctgctt
     6121 ttttcttgtc catagcctgt ggagttcctg acaaggcacg actgtaaact cctgatagca
     6181 cacgaatctc gtcagtcaaa taagcatgat aagcacctgc tgctgtaagc actagccagg
     6241 cttttagcag ctcccaattc ttctcagaat aatagtcagc tgcaaattct gtccagaacc
     6301 gctcctctgg cacaacaacc ttgtctggta cttcacctaa aatcacagta aatatattat
     6361 ctaaaggcaa ttctggcact agcttggtaa actcggccca gtcataaggg tggtaaagct
     6421 tggcatactc tgaatattcc tcacgagaaa ggacataatc tgccagctgt ttatcaagcg
     6481 tgataacctt atccagcaag tccttaacct cttcatgtga aaagccaaat ttaggcaata
     6541 gctcctcttg catgccacgc cagatagcaa gcagctcttt gcctttgtca ttgtctttgg
     6601 catagtaagt ggtatctggc aggataagac ctggtgcctc tgcccaaagg acatttaact
     6661 gagcattcat aaagtctggt gctacactaa atggaaactg atttggtttt ccatttagct
     6721 cataatcagc caccttgcta gcaaactcgg caaaagatcc taaggccttg tattcttcaa
     6781 ttaagtccaa ggctggcgct acgcccacct gatcacgctt gtcataatct gcaaccaagc
     6841 ggtgaaactt gacaaagttt tctaatatag cgtcattggg aacatgctca ccagccaacc
     6901 aagcatctgt tgtggtcagc attaagtcct caatctcatc tgctaggtct gaaaagcccc
     6961 ctgtacgagg cttatcgtct gggataacag ctgtttctgc ccattgacca ttgacggctt
     7021 gataaaaatc ttcttgatat gttgtcatga attgctcctt ttttaaatta aaccattatg
     7081 ttaggactag cttttactcc tcataatgta atctcttaca ttttaccaaa aaatcgttca
     7141 aaatactcgt tttatattaa ctttctgttc aaaaataagc tcattcttcg tatcgcatgg
     7201 catagatagt aaacgcttag ctgctttggt ccttttatca gtaagattaa tcataaaaac
     7261 tgaacaatca ctaagaaatc aaacgattct tctccagctt catgaaaaca gccctcacaa
     7321 tatgccaaaa actcagcagt aatagcaaaa ggccctatca gtcctgacaa aagaattgca
     7381 ccccaaaggt gaagataaaa cctaaagctt aagaactttt tctatgacat taaaattaga
     7441 aggtgaaatc aagagttatc aatcattatt tcacgcctac agagtgaaag ggactgaaag
     7501 cgcataacta aaaggactga accctgtttc atacaaagct caatcctaat ctataaggtc
     7561 cagctttttg ggtgtggtac acctgatagg cttttttagc taatctgccg ctaaaatcct
     7621 caaaacctgc tgctcaatag ctgctggcgt cagctggtat tcctctaata gataatccat
     7681 ctgtccgacc tgaccgaaac gttcgtccac ccccatacgg taaactggag tattactttc
     7741 ctgagccagt agctcacaga tagcactccc aagcccaccg atacgattat gattttcaac
     7801 ggttagaaca ggactgcctg taagtagacc ctttagctca tcggccagtg gctttaccct
     7861 gaaaacatca atcacaccga tagagtagcc ctgctctgcc attttatcgg ctacctctaa
     7921 gcaccttttg accatgatcc ctgagcaagc cagcacaagg tcttttcctt gacgcaatag
     7981 gcaatagcca ttagaaaagt cctcatgccc ttgataaata gcctctggct ttttacgaat
     8041 ggttcgaatg tattttaggc catcgagtga tagggtttcc tttaaaacag ctttaaattg
     8101 aacgtcatca ctgacctcat aaacaatagc ccttggaatc aggcgcagca gtcccagatc
     8161 ctcaaagggc atatgggtgc cgccattcat ttccgcacta actccggcat cagagccaat
     8221 aaccgttgcg cctagctggg cataggctaa tgaaagaaac agctgatcaa acacacgacg
     8281 tgaggcaaag ggaccaaagg tgtgtaggta aggcttatag cctttaatcg ccaggcctgc
     8341 tgccagaccg accatttctg cttccataat gcctacatta atatagcgct tgccaaacac
     8401 ctgatccaaa tggttggtgg ccattgagct tgataaatct gcctctaaga cgactacctc
     8461 agggtgctct tggttggctg caatgaggaa atctcggtaa acatgacgca tttcttgact
     8521 tgctcgagtc atcttgtcac ctccaaacta gctcgtagct ttctgacagc ggcagcaagc
     8581 atctcctttt cggctgctgt tggtcttaga tggtggttag ctgccattga ctctagctgg
     8641 ctaacaccct gacccttgac ggtatctaag acgatacact tgggcttatg acttgatgac
     8701 gcctgcaaag ccctgatggc ttcaaaaata gcctgaacat ccctaccatc tacacgtaag
     8761 ctttcaaagc caaatgccgt aaacttttca acaaaatcac ctggacgaca gattgcctcg
     8821 gttgttccat ctaattgctt cttattgtca tcaacaaaga caatgaaatg acttagctgc
     8881 tggtgtgccg caagctggat agcctcccag cattggccct cgtttaattc cccatcacca
     8941 acgattgcat aggtataatg tggtgactgc tcaagcgctt gagcataggc aatgcccgtt
     9001 gctacgctaa ttccctgacc aagagagcct gtcgtcatgt caataccagg cgttaacaga
     9061 cgatctgggt gcgagggcag acttgttcca ttggtattaa gagactgtaa aaaggcctta
     9121 tcaaaaaacc cctttaagta gagagtgcta tagagggcag gacccgcatg tccctttgat
     9181 aacaccagat aatctctatc tgactggaca aagagctctg gtgtcatggg catgatttct
     9241 ccataaagca cagccagcaa ttctacaata gacaagctac cgccataatg accaaagcca
     9301 agatgattaa gagtctccaa ggtatttaga cgaatctctg ctgcgaatcg cttcacatct
     9361 gttagaggct catcactcaa aaccatgctt attcctcctt agctactgat tttccaacaa
     9421 cagaaagccc aacaagtcca gctaatatca caaaaatacc aatcacaata gctgtcacac
     9481 cacctatgct gttaagtgtt cctagtaaaa tacctgataa gccaaaatcg gcatctgaga
     9541 aggttgagcc ctcaaagccc aagccgccta aaacaggcat caagaaaatc ggaagatagc
     9601 taataagaac accctgtaaa aaggctccca cagttgcacc gcgcacacct ccagaagcat
     9661 tcccaataac accagctgtg gcaccacaga agaaatgagg cacaacgcca ggtaaaatca
     9721 ctgtcgttcc acttacgatc atcacagcca tgctcacaag gccaccaaca aagctagaaa
     9781 caaagccaat cagcactgca ttgggggcat aaggataggc aatcgggcaa tccaaggccg
     9841 gcttagaatg tggcactaat ttttcagaaa tgcccttgaa ggctggaaca atttcaccca
     9901 gaatcaaacg aacaccagct aaaatcacaa agacgcctgc agcaaactgt cctgccaact
     9961 gcaaggcaaa gaccaagcca tgtgtgccag aggataattc cttactaatc caagtaggac
    10021 cagcaaaaat agctacaatc aaataaatga ttgccattga taaggtaatg cttactgtac
    10081 tatcacgcaa aaaagcaagg ctctttggaa aatcaatgtc ctctgttgac ttggttttgt
    10141 ctccaacaag acctcctaca aaaccgctta accaataacc aagagagcta aaatgcccca
    10201 aagcgacctt atcgttacca gtcagctgga tcatataccg ttgcacaaga gccggtgaaa
    10261 cactcatgat aatccctaag gccagcccac caaacacaat caaggacact gacgtcaagc
    10321 ctgcaacaga cataatcaca gcaatcatac aggccatgta aagtgtgtga tgccctgtca
    10381 agaagatata cttaaatcgg gtaaagcgag caatcaaaat attaaagatc attcctgtaa
    10441 acataatcag agctgtcgct gacccatagg tcgtcaaagc aactgcaaca atagcctcat
    10501 tatttggcac aacaccagac agatgaaagg catgctcaaa catcgttcca aaagggttga
    10561 gtgagccttg cacgatacct gcaccacctg aaaccactaa aaacccaaca aaggtcttaa
    10621 tgcctccctt aacaatgtca ggagcaggct ttttttgaag taagagacca acaatagcaa
    10681 tcaaggcaac caaaatagct ggtgtgctaa caatatcaag taaaaatgtc atcttatcct
    10741 ccttctaaac aagccccttt tcctggcaaa tagcctttac cagactagtc aattcgtcca
    10801 tatcaatgat actatttaaa atcctcacat ctcccagatg ctctgccgag tctgccaaat
    10861 cacgcccaac aatccacaca tctgccgctg tgggatccgc gccaccaaga tcataatgct
    10921 ccacctcaac accggttact cccaagtcct ttaatacgga ttcgatattc atctgaacca
    10981 taaagctaga ccctaagcct gaaccacagg ctgtaccaat tcttaatgcc attttatgcc
    11041 tcctctgcaa taatagtttt aatatcctca aatgatttag acgcaagtaa agccttgacc
    11101 tgctcattgt ctcttaaaat ggtcgtcagc cgagacaggg cctttagatg tgtttcatta
    11161 tcaatagcag caatacaaat taacaaacga atctcctgct taggatcatc taacaaataa
    11221 atcgggtgct ctaaaacaag catcgacata cctacctgat tcacaccatc ctctggcctc
    11281 gcatgtggga tagcaatccc cttacctaga ttaataaaag taccaaactc ctcaacctta
    11341 gcaatcatag cctccgggta gctcgcttga atctgcccac tctctaacaa gggctgagcc
    11401 gccaaataaa tagcctctct ccaccccaat tgctctgagg ttgattgata ggttttcttg
    11461 gtaattaagt cttgtaacac tggtcgaata tcctttcttt tcacaccttg tcttaaatat
    11521 tgctgcaaag caaagcgcag cttttctttt tgatgaatga ccgcatatga gctgataaga
    11581 tggagcagct cttcaacctc tagccgatag ccaatatctg gaaaatcacg attaaccaag
    11641 ctgaccagct gaaaagcctg ctcatcagtc attatcatag ggactaaata aaagggctta
    11701 tcagtctcta atcgtatcgt tgaaaaaacc aaatcatagc cgctcttatc taattgccca
    11761 agctgatcaa gccttgaaag cccccgaaaa gcaatatcag gaaataaaag ctttaaatgc
    11821 tccttgatca ttaaagaaga actaacacca ttaggacaga caatcacagc ctgataggct
    11881 tgacgatgaa aatctcttcc ctgctgcttt aaatagcctc caaaatgaag aacaaaataa
    11941 gcaatttcac tatctggtat aggactaccc agctccttgg ctaaaggctc cagagactgc
    12001 tttaccaagt caaaaagctc agaataacta tccttaatcc gcaaggtata atcattatca
    12061 cttggcaaac catagcgcaa acggtaatag gctggaatca aatgcctttt caaattctcc
    12121 ttgagctgat ctgcctgact aaagcttagt aaagcaaccc cctgcatttg atcaacaatc
    12181 gcaacggtta gtgattcaaa gaaatcatca ccaacagtac cctcaccctc aaagcagccc
    12241 gctaacagca attgaaaata ggcctcatca gcttcaaata gctgatactt aagagacaat
    12301 tgctgcatta tttctgccac caaaagggcc gttagctgat ccagctgctc agaaaccact
    12361 acctgtcttt gcttgaccct atcaacccgt ctttggtaac gacataaaat aaagatgaca
    12421 gcgtacaaac agacctgcag acgatcaagg atcggagaca tctgaaaggt ctgataaaaa
    12481 tggctcacac gtttttcaag cgcttcaaac gacacctgat agtgccaaga agccaaaata
    12541 tagtccaagg cccacaagcc aataggagat ttaagcaaag tagcaatcat tactaaagcc
    12601 aaccggtgct tattaatctc atcaccaact aagatatagc cgcttgctct ggtatacttt
    12661 aattccaagt caacatctgc cagcttctgc cgcaaggcct taatatctgt caaggctgtg
    12721 ttcttgctga cctttaaaaa gtcctgataa tgactatttg aaacaaaatc cctgcggcaa
    12781 aaggtataca gatagataag attgatccgc tctgcctgag aaagataaac ctgctcagca
    12841 ttaatcaacg taaacaaatg atctgactca gccttaagct gctgactgat ccgatagcca
    12901 gaccttgttg catctagctc tgagagctca tgctgagcca aaaactcatt cagctcatca
    12961 atacggtcct taatctctct aatggtgaat tttgtcttaa cactcagctc gtaaagtgat
    13021 aagtcttgat aagtcatcaa cgtcatcaaa atgacaactg ctttgctatc aaccatttga
    13081 tttcctttct aaattcattc tatcgaaaac ggttacaata aactagtccc cattgggcac
    13141 aatttcttat ccaacatcat caacagccct tgggctcaag atgccaatct aaacaggcta
    13201 ccagctcctc ctaactatca ataaagagca aacaagccca tctctgccgc taagcaattg
    13261 tccccatgat ttcctaagtc caagccaaag ctaaagctct ttggagtaat aaccgtcaaa
    13321 aatgttccaa ataatcaaaa aaactgattg acctcatcag catgtgataa ctctagatat
    13381 aagcctaaaa caagattaca gacttaatag ttaactggta atcttttatt ataccacgaa
    13441 aacggttacc aaaaaagact tgtgttttat tattttaata atataatgaa actataagat
    13501 atcttattaa atgacaaata actaccatct tggttagaaa ggagtaaagc taattaaccc
    13561 ttagtagatc accatcgttt tcagaaagga aattcaaaat gaaaaaagta aaacaattga
    13621 tcatcgcaat gatagcgtcc ttattactca ttgctaacac tgtaccttcc attgtatatg
    13681 ctagtgaagt gactaaaatt caacaggaag aaaaagtaat tgaagaaaaa ttatcacaac
    13741 ctctagaaat ttcaaaaagt gagttagata cattaatcca agagaaaaaa gctctttatc
    13801 caaatttaac agaacaagaa atgcgtgaaa ttgcgtataa agccatgagt ccatacactt
    13861 ttagagctag tgtatgggac gggcaaggag taaccttaga tgaattcgct tgggcttttg
    13921 atgttattgt aggcgggtta attagtggat atgcaaccat cggaaagtac gttgccaaac
    13981 atggagtagc tgccgctcga gctgtactta gccgagctgc aaaagctgca gctcaacgac
    14041 ttggtgtact aaccggattt atttccggtt tacttagagc tgcattctca gtaataaaca
    14101 tttactataa tgtcggatat gccctagcac aatatgtcga tgctcgagat tatcacccaa
    14161 ataacggtcg tataaatgcg tgggcttaag aactatattt gttattttat tattgtaatg
    14221 tcagtttata cagcaatagc atattgtttc aatcgcttat ccttatcatt tactccaaaa
    14281 ctagttttct attcggccat aaccacctat actttttaca taacaaaaaa taaagactga
//
LOCUS       DARYUW010000051        14028 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYUW010000051 DARYUW010000000
VERSION     DARYUW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14028
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..165
                     /locus_tag="TVW11_001522"
     CDS             <1..165
                     /locus_tag="TVW11_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365609.1"
                     /translation="VTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIA
                     TDQKLGGDFS"
     gene            162..554
                     /locus_tag="TVW11_001523"
     CDS             162..554
                     /locus_tag="TVW11_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365610.1"
                     /translation="MTALEKIRAAIRQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASTYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            573..857
                     /locus_tag="TVW11_001524"
     CDS             573..857
                     /locus_tag="TVW11_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365611.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGCLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(1056..1304)
                     /locus_tag="TVW11_001525"
     CDS             complement(1056..1304)
                     /locus_tag="TVW11_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1365612.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(1358..2278)
                     /locus_tag="TVW11_001526"
     CDS             complement(1358..2278)
                     /locus_tag="TVW11_001526"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1365613.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            2512..3141
                     /locus_tag="TVW11_001527"
     CDS             2512..3141
                     /locus_tag="TVW11_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1365614.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            3240..4517
                     /locus_tag="TVW11_001528"
     CDS             3240..4517
                     /locus_tag="TVW11_001528"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1365615.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            4531..5193
                     /gene="deoC"
                     /locus_tag="TVW11_001529"
     CDS             4531..5193
                     /gene="deoC"
                     /locus_tag="TVW11_001529"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1365616.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            5180..5569
                     /locus_tag="TVW11_001530"
     CDS             5180..5569
                     /locus_tag="TVW11_001530"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1365617.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            5660..6712
                     /locus_tag="TVW11_001531"
     CDS             5660..6712
                     /locus_tag="TVW11_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1365618.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6839..8371
                     /locus_tag="TVW11_001532"
     CDS             6839..8371
                     /locus_tag="TVW11_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365619.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            8364..9428
                     /locus_tag="TVW11_001533"
     CDS             8364..9428
                     /locus_tag="TVW11_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365620.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            9430..10386
                     /locus_tag="TVW11_001534"
     CDS             9430..10386
                     /locus_tag="TVW11_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365621.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(10424..11680)
                     /locus_tag="TVW11_001535"
     CDS             complement(10424..11680)
                     /locus_tag="TVW11_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1365622.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(12200..13915)
                     /locus_tag="TVW11_001536"
     CDS             complement(12200..13915)
                     /locus_tag="TVW11_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1365623.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         4038 a         2515 c         3280 g         4195 t
ORIGIN      
        1 gtgacctatg acagccttgt cggtcagacc aggaggcact ttgatgacaa ggtcgctcag
       61 gccagaggac tggccactaa gttcaagacc gtaaaggagc agctagagga ggggatcgaa
      121 aggacaatcg ctactgacca aaagctagga ggcgactttt catgacagca ttagagaaga
      181 tcagagctgc tatccgtcaa aaggaagagg agctagagga gctgcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctgc
      301 aagagctcta tgcctctacc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gcctgataac agaccaatat accgttctaa cgaggctgat tgatgactat cagcaccgaa
      421 cagagcagtg ctatcacgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggctatag agaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga agatgattgc tatagagatg atcttaaccg
      601 gacaagagcc gatcaggact ttaaagaaag agctggatag gagattagtt cagtccatat
      661 gtgccccctt gaccttaggt tgccttcatg cccttcaaag gcgctatgac agtgaggtat
      721 ctcggattgc cacagacacc gcagatcata ttcagaccat tgtcaatcag ctagatagca
      781 gcattagagg gcaaggcagg acagcactag agcaagcgat caagacgcag aacaggggct
      841 atagcagcct gatgtgagac aggaaggact tactgtccta ccagctacag tcactacact
      901 gctagagctt gcggtgtgag cagcagtaag aggcaaaggc gttaccccag agggattgat
      961 ggatcaccat cactagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt ttcattggtt atgtattagc taagctttgc agcaagacgt
     1081 gctttatcgc ggcttgcttt atttttatga atcaaacctt ttgattgggc tttatcaatg
     1141 cttgaagaag cagcgcggaa aagctcttca gatgggttag cttcaaatgc cttgatagca
     1201 gtacgcatag ctgatttttg tgctgaattt ttttcgtttg ctttaacgtt aagctcagcg
     1261 cgtttaatag ctgatttaat atttgccaat gttttcacct ccaaattaat ctaactacac
     1321 cattatatag aaaatatagg tgtttggcaa gcacttatca ctttttgaga taaatttcat
     1381 caattttatg gtctgcagct ttatgaagaa tgagctcagc tcgattgcgt gtaggctcaa
     1441 taaacttttc cagattttct aggttaattg ttttccagac tttttttgca aaggcaatgg
     1501 cttcattttg tggcaatgag gtatatctag tgtaatagtt agccggatca tgcttagcca
     1561 gctctaaaag gcttaagaac cgttccaaat accattgctc aatatgatgg ctatctgcgt
     1621 caatataaat tgaaaaatca aaataatcac tcatatacaa tcgattattc tgttgatttt
     1681 gaaaaacatt aatcccttcg atgatgagga agtcaggatt ggtaaaggtt tgctgctgat
     1741 caggaacgat atcataaatc tcatgcgagt aaacaggggc tgatgcggtt tgtcctccct
     1801 tgacagtatc cagaaagttt aacaatagct ccatattata ggattctggg aagccctttc
     1861 gattcagcat attgtttttg atcagtgtgc tattagggta caaaaaacca tctgttgtga
     1921 ccaactcaac agtgctggtc ttgtgtgtgc gcgccaaaag aagctgcaat aacctgctag
     1981 ttgtggactt accgacggca actgagccag aaatcccaat aataaagggt ctttgctgaa
     2041 tatctttttt tagaaagagg cttttagaaa aagacaggtt ttcttgagcg attttataga
     2101 cttgaatgag atgaatcaag ggaaggtaaa cctcaacaac gtcgttgata tcaatattat
     2161 cattcaaact ggtgatgcta gtaagctcct cttgagtcaa taagggcttg cttttttgat
     2221 gtaattgctt ccaggatttt ctggaaattt tttcaaaagt aataaattcg tttgacatag
     2281 ttactcctac taattggcag tgcttacatt ataacatgtc aataaaaaaa ttgaaaaatg
     2341 tttcgtctga aattcttaaa aaaacactga aaaaccctat aaaaatcgaa caattttagc
     2401 ctaacaattg gctaatataa agttaatcgg tcaatgttcg gaatatatgg ttcgataaac
     2461 gaaaaaccaa gaaaaacaaa cgtcttgtaa accatttcaa agtgtgatag aatgaaaaag
     2521 catcgaaaaa agataggaaa acacatgaca aaaatgtatt atgatgaaaa tccagatagt
     2581 gctcatgata tccatcaatt gacggtcaat ttgttaggac agtcctttac ttttttgaca
     2641 gattctggtg ttttctcaaa aagaatggtt gattttggaa gtcaggtcct gctcaacaca
     2701 ttagattttc aagaaggtga tcgtctgctt gacttgggct gcggctatgg gccgctagga
     2761 cttagcttgg caaaggctca aggtgttgag gcgactctag tagatattaa tcatcgcgct
     2821 gttggcttag ctaagcagaa tgctgagagt aatcaggttg aggcgaccat ttttcaatca
     2881 aacctctatg acggtgtgac agggacattt gagcacatca ttagtaaccc acctattagg
     2941 gcagggaaaa aagtggttca tgagattatt gaaaagagta ttgatttttt aactaaaggc
     3001 ggtgatttga cagtcgttat ccaaaagaag cagggagcac caagtgctaa agacaaaatg
     3061 gaggccgttt ttgggaatgt gactattctc aaaagagaaa agggttacta cattttaaga
     3121 agtattaagg aaaggaattg agctcaagtg taaaaagtgg tattaaaaag catagcggta
     3181 ttttagtaag agttgccttc taatatcact attttctcag agcttttggt atcttgttga
     3241 tgagagcagt tgatttaatc caaaaaaagc gtgatggtaa agagctatct accgaagaga
     3301 tccagtggct gattaatggt tatgccaatg gtactgtgcc agattatcaa atgtcggctt
     3361 ttgcaatggc gatctatttc aagggaatgt ctacacgaga aactcgcgat ttgaccatga
     3421 gtatggttga gacaggtgag cagattgatt tgtcagctat agctggtatc aagacggaca
     3481 agcactcaac aggtggtgtt ggtgataagg tgacactcat cttagctcct ctagttgcta
     3541 gctttggcgt tcctgtagcg aaaatgagtg gacgcggctt aggccacacc ggtggaacgc
     3601 ttgataagct agaatctatc aagggctttc agattggtcg gacccaagag gaatttatca
     3661 agcaggtaca agagatcgga ctttcagtta ttggacaatc agataagctt gtgaaggcag
     3721 ataagctgct ttatgctctt cgtgatgtga cggcaaccgt tgatattgtt cctttgattg
     3781 caagctctgt tatgagtaag aaaattgctg ctggcgctga tagtattttg ctagatgtta
     3841 ccgttggtga cggtgccttt atgaagacta ttgaagatgc tgagaagctg tctagactga
     3901 tggttgacct tggtaaggag gttgggcgtc agacagtggc tgtcattaca gatatgagtc
     3961 agcctcttgg tcgtgctatc ggtaatcgct tagaggtgct agaggcaatt gatatcatga
     4021 aaggcaaggg acgcaaggat attactcact ttatttgtga gctagctcag attatgctgg
     4081 agcttgctgg tgctcaacac tctcttgagg atattcacca tcatttggtt ggcggagcag
     4141 ccttaaaaaa attagaagag atggttgttt atcaaggagg tgatcttgag gacctttatc
     4201 gtccatcaca ggcggctgtt caaacagagg tttttgcgtc agaagatggt tacatcacag
     4261 cattgcctgc tcttgagttt ggattgtttg caatgaggct gggtgctggt agagcagtca
     4321 aaacagatag tctggattat gaaacaggga ttgtctttga caagaaggtt ggtgacgctg
     4381 tcgctaaggg agagcgcatt gcagttgtct tttcacagga agccctagac gaaaaaatgc
     4441 ttacagaatt tgaaaaaaat gttaaaatag gggcggaaca cctagaggct aacgaaatta
     4501 tcaaaatcat ttcctaagga ggagtataac atgaatatta acaagtatat tgaccacaca
     4561 ctactaaaag ctgacagcgt tcaatcgcag cttgaccaat taattgagga ggctaaagcc
     4621 tatgactttg ctagcgtttg cgtcaaccct tgctgggtag cctatgctgc aaaggcttta
     4681 aagggaacag atgttaaggt ttgtacagtt gttggttttc ctttaggtgc aactacctca
     4741 gcaacaaagg cctttgaaac aaaggacgct attgaaaatg gtgctgatga gattgatatg
     4801 gttatcaata ttggtctgtt aaagcagggt gactaccaag ctgttgaaga tgatatgcgt
     4861 gcagtggtag aggctagcgg agacaaatta gtcaaggtga ttatcgaggc ttgcctcttg
     4921 actgatgatg aaaaggttaa ggcttgtcag ttggcggtaa atgcaggtgt tgactttgtg
     4981 aagacctcta ctggtttttc aactggcggt gcaaccgttt ctgatgtcaa gctaatgcgt
     5041 caaacagttg gtccagacat tggcgtaaag gcagctggtg gtgctcgttc tctagaggac
     5101 gctttagctt ttgtcgaagc aggagctaca cgtattggaa cttctgcagg ggtaactatt
     5161 atgaaaggtg aagttgccaa tggaggctac tgatttagtt tcgttagcca ttgaagctag
     5221 taaaagggct tatgtgcctt actcacattt cccgatcgga gctgctttaa agacaaagga
     5281 cggaacaatc tatactggca ataatatcga gaatgccagc tttggcttga ccaattgtgg
     5341 ggagcgaaca gctattttta aggctgtttc tgagggacat cagcagcttt tagaaattgc
     5401 catttatgga gagactgatg agccaatctc tccttgtgga gcctgtcgtc aggtcatggc
     5461 agaatttttt gaagccactg ctccagtaac gctaattgct aaggacggtc gtaccatgcg
     5521 cacaactgtt ggcgagttac ttccttattc gtttacagat ttatcgtaat ctggcttaat
     5581 tttgttatct agccattagg ctttatattt actttcggca attggtttgc tagaaatatt
     5641 tttaggaggg ttcatattca tgaacaagaa atttattggt gttggtttag cttctgtagc
     5701 tttattaggt ttagttggtt gtggtaatcg taacgcttca aagggatctg gtgatgctaa
     5761 aacagatttg aaggtagcag tggttactga cactggtggt gttgatgata agtcatttaa
     5821 ccaatcagct tgggaaggct tgcaggcttg gggtaaggac aatggactaa caaagggttc
     5881 aggctttgat tacttccaat ctacaaacga gtctgaatat gcaactaaca ttgatacagc
     5941 agtttctagt ggttatgagg ttgtttatgg tatcggattt gccttgaagg atgcaatcag
     6001 taaggctgct gatgacaaca acaaagtaca atttgttatc attgatgatg ttatcgaagg
     6061 caaagacaat gttgctagcg taacatttgc tgataacgaa gctgcttacc ttgcaggtat
     6121 tgcggcagct atgactacaa aaacaaaaac agttggtttt gtaggtggta tggaaggaac
     6181 agttgttaca cgctttgaaa aaggctttga ggcaggcgtt aagtctgttg atgactcaat
     6241 caagatcaag gtggactacg ctggatcatt tggagatgcc gctaagggta agacaattgc
     6301 agcagcgcaa tacgcagcag gtgctgatgt tatctatcag gtagctggtg gaacaggtgc
     6361 gggtgtcttc aacgaagcaa gaacaattaa cgaaaaacgt gacgaagctg ataaggtttg
     6421 ggtaattggt gttgaccgcg accaaaacga agaaggtaaa tatacatcta aggatggcaa
     6481 atcatctaac tttgtacttg catctactat aaaaggtgtt ggtaaggctg ttcaattgat
     6541 caataagcag gcagcagata agaaattccc tgcaggtaaa acaactgttt atggtctgaa
     6601 ggacggtggt gttgagattg ccacaacaaa tctttctaaa gacgttatca aagccatcga
     6661 agaagcgaaa gaaaaaatta aatctggtga cgtaaaagtt cctgaaaagt agttactgga
     6721 aaagagcgac cttcgtcggt cgcccttttt agagtggaac accttttgct tcagtaaagg
     6781 ttgtgacaaa tggctggctt tactgaaaca aaagattaaa ttgaaaggaa ataatcctat
     6841 ggcacagcat gtcattgaaa tgaaagagat tacaaaaaaa tttggtgatt ttgttgcgaa
     6901 tgaccatatt aatttgaatg tcagaaaagg cgaaattcat gcattgttag gagagaatgg
     6961 tgcaggtaaa tcaacgttaa tgaatatgtt agctgggctt ttagagccaa ctagtggaaa
     7021 cattgtcatt aacggtcagc ctgttgttat tgactctcct tccaaatctg ctagattggg
     7081 tattggaatg gtacaccagc actttatgct agtagaagct tttacagttg ctgagaatat
     7141 cattttagga aatgaagttg tcaaaaacgg ttgtcttgat ttaaaaaagg ccagcaagga
     7201 cattaaagag ctttctgaga aatatggttt agctgttgat cctactgcca agattgctga
     7261 tatttctgta ggggcacagc agcgtgttga aatcttaaag accttatatc gtggtgcaga
     7321 tattcttatt tttgatgagc caacagctgt tttaacgcct gctgaaatac aagagctcat
     7381 ggaaatcatg cgtaaccttg ttaaggaagg caaatccatt attttgatta ctcataagct
     7441 ggacgaaatt agagcagttg ctgatagagt cactgttatt cgacgtggga aaagtattca
     7501 aacagtagat gtagcaggtg caacctctca ggacttggct gaaatgatgg ttgggcgttc
     7561 agtttccttt acaacagcta aaaaggcagc agagccaaaa ggggtggtgc tgtcgatcaa
     7621 gaatttagag gtcgatgaaa atcgtggaat cccagcagta aaggggcttt ctcttgacgt
     7681 tagagctggt gaaattgtgg ggattgcagg gattgatggt aatggtcagt cagggctgat
     7741 tcaggccatt acaggcttga gaaagactag atctggtagc attacaatca aaggtcagga
     7801 ggttgttcat ttaagctccc gtaaaatcac agagctatca gtggggcatg tgcctgagga
     7861 ccgtcataga gatggcttag tgctggacct ttccttggct gaaaatactg cccttcagac
     7921 ctattataaa gagccactaa gtaagaacgg tattttaaat tacaatacaa tcaatgatta
     7981 tgctcgtaga ctgatgaagg aatttgacgt tcgtggtgcc aatgaattgg ttccagctcg
     8041 tggattttct ggcggtaacc aacaaaaggc tatcattgca cgtgaggttg accgtaaccc
     8101 tgatttattg attgtcagtc agccaactcg cggcttggac gttggtgcta ttgagtacat
     8161 tcataagcgt ttgattgaag agcgtgacaa aggcaaggcc atcctcgttg ttagctttga
     8221 gcttgacgaa atcttgaatt tatctgaccg tattgcagtt attcatgacg gtaaaattca
     8281 aggcattgtg ttgcctcaag ataccaataa gcaagaattg ggaattttga tggctggtgg
     8341 ttccattgat aaggaggaga gtcatgtcta aaaatgcaca aaagattgct gtgccaatga
     8401 tttctatctt gttaggattc ttacttggcg ctattgtcat gtttatcttt ggctatgatc
     8461 caatttgggg ctatgagggc ctatttcagg tagcctttgg tagtatcaaa aatattggtg
     8521 aaatcttcag agcgatggga ccactaatcc tgattgcact tggttttacc gttgctagcc
     8581 gtgccggctt ctttaatgtc gggctgtcag gtcaagcttt ggctggttgg attgctgcgg
     8641 gctggtttgc tcttgtcaat cctaatatgc ctcgtccgct tttaattctg atgactgtct
     8701 tgattggtat ggttgccggc ggaattgctg gcgctattcc aggtattttg cgagcttatc
     8761 ttggtacaag tgaagttatt gttaccatta tgatgaatta tattattctg tatgtcggta
     8821 acgctatcat tcaaagaggc taccctgaaa gtgttaagca aagtattgat tcaaccatac
     8881 aggtcagtga taatgccagc tatcaaagtc aatggctgtc agatttaacc aataattctc
     8941 gtattaatat cggtatcttt tttgcgctta ttgcaattgc agttatttgg ttcttactaa
     9001 acaaaacaac cctcggattt gaaattcgtt cagtaggtct taatccacat gcttcagaat
     9061 atgcaggtat gtccttaaag cgtacgatta tcctatcaat gatcatttca ggtgctttag
     9121 caggcttggg aggagttgtt gaaggcttgg gaacctttga gaatgttttt gtacagggaa
     9181 gctctctagc aattggtttt gacggtatgg ctgttagctt gcttgctgcc aattcaccga
     9241 ttggtatctt cttctcatca ttcctatttg gggtgttgag cataggtgct cctggtatga
     9301 atatcgcagg aattccacca gaattggtaa aagtagtgac tgcctcaatt atcttctttg
     9361 taggtgctca ctaccttatc gaacgctata ttatcaggcc taaaaaacta gtaaagggag
     9421 gtaaataaga tgagtttagt tactattttt gctttattgg tttcatcaat gcttatctat
     9481 gctacacctc ttatttttac aagtattggt ggtaccttct cagaacgagc tggtgttgtc
     9541 aatgtcggcc ttgaaggcat tatggtcatg ggggggggtt caggcattgt ctttaatctt
     9601 gaatttgctc atatctttgg taaagctact ccctggcttg cagttttggt gggaggagtt
     9661 gttggattga tcttttcatt gatccatgcg cttgcaacga ttaactttag ggcagatcac
     9721 attgtcagtg gtacagtgct aaatctgctg gcaccatcgc ttgccatttt cttagttaag
     9781 gtgatgtacg gtaaggggca aactgataat atccagcaat cattcggtaa gtttgatttt
     9841 ccgattctct caaaaattcc agttcttgga gatatattct ttagaaatac tagcttagtt
     9901 gggtatttag ctgttgcctt ttctttccta gcttggtttg tgctttacaa aacaagattt
     9961 gggttgcgtt tgcgctctgt aggtgaacac cctcaagcag ctgatacact tggtattaac
    10021 gtttacctca tgaaatatta tggggttatg atctctggtt ttcttggggg tattggtgga
    10081 gctgtctatg cacaatccat ctctgttaac ttcgcagtga caaccatttt aggacctgga
    10141 tttattgccc ttgccgctat gatttttggt aagtggaatc cggtaggtgc tatgctatct
    10201 agcttgttct ttggattatc acaaagctta gcagttattg gggcacaatt accagtattg
    10261 gaaaaaatcc caacggttta ccttcaaatt gcgccatacc tattgaccat catcattttg
    10321 gctgctttct ttggacaagc agtggctcca aaggcagacg gtgttaatta catcaaatca
    10381 aaataaaaaa agctcaatgt caactgtagt gggtgactga tagctaagca cgagagaaga
    10441 cgaatgtcgt cttctctttt gtgatattca aagcgaggta gatacgtttt ttaaagttgt
    10501 caaagttccg aaatccgaaa gcattgcgct tgatatcttt gataagtttg ttagtggctt
    10561 ctaacttagc gttagaataa ggcagttgaa tggcattggt gatgtaatct tggtagcgac
    10621 taaaggtatt tagagctgtt ttaaaagtct gattaagatg tggtagtgtg tcatgaatta
    10681 aaccaaagaa atgcttggca ttcttttctt gcaggtgaaa aaggagcagc tggtacaggt
    10741 cataataaga gtttaactca ggcactagtg agaagatctt attgagacat tctctaggag
    10801 ttaaggtttg tctgaaggtg cgggaataga aaggcttaag agaccgtttt ctgctatcct
    10861 tttgaataag cttccagtag tacttaagag ctctatattt aagagacttc ttgtcaaatg
    10921 gtttcatgat gtcactacgt atttgcttga gagctctatt gatgtgctgg acaatgtgaa
    10981 aacgatcgag aacgatttta gccttaggaa atagaatttt aatgagagga atataacttc
    11041 cagacatatc gacagtgacg actttcacct tgtttctagc ctctttagag tacttaaaga
    11101 aatgatttcg gatggttgtt tgacgtctat tatcaagaat ggtaatgatt ttcttagtgt
    11161 taaaatcctg agcaatgaag gctaatttac ctttctgata agagaactca tcccaagaga
    11221 gaacttctgg caaattggcg taatcctctc ggaaatgata ctgcttaagc ttgcgataga
    11281 cggtagaagt ggagatagcg agcttagaag cgatatgggt gagagccttt ctgttgagta
    11341 aaagctgagc gattttctgt ctcactatct cagaaatttg gcaatttttc ttaaccaggg
    11401 tagtttcaga tacagtgact tttcgacagg atttgcattg aaaccttctt tttttcaaac
    11461 gaatgagact aggaaagcct ccaatttcga taaagggaat tttagagggc ttctggaagt
    11521 cgtatttgat ttgttttccc gcacacagtt tacatttagg agggttatag tctagtgtag
    11581 cgatgacttc aatatgagta tcatgctgga tagctttagt caaggtgata tgtttgtctt
    11641 tgattccaat gagttgtgtg gtattattga ggtgttccat aagatacctt ctaaatgata
    11701 gtttagtcgc ttttcatgat aagtcttatg ggactttttt gatactcaaa aagccctata
    11761 atctccacag tagccttacc cactacagaa attatagagc catcttagaa cactggactt
    11821 gttcgctttt taatgaatta aatttagtag atcctttaaa ggcatgctat caagcttttt
    11881 atccttgact tttgtttagc aagtgaagtg ttcacaaaag ctagctaaaa cactgagctg
    11941 acaatgtaga gaatggctcg ttttgacaag gttagagtgc tttttgctgt atggttttta
    12001 atccacgcac ctgaaaaaga aaggacagga cctgtgcgag cttacttgtg gttagtaggt
    12061 ttcaattcat gctcccaaaa aggaagcaac gcaactctga gaaaggtctt agaccacttt
    12121 cccagtttgc ctcacagcta atggtgtaaa acaaatagac caccctgtaa caggtggtca
    12181 tggttagata tcagctcatt taagagacaa aggcgttgat ttcagattca atattggcaa
    12241 ttttttcttc ggcaagcgca agggtgtcac caacagttgc gatataaaat ttaatttttg
    12301 gctctgttcc tgatggtctt acagcaaacc atgaatcatc agctagggta tattttaaga
    12361 cattgcttgg aggagtggtt agctgggttt gaccagcttt atgagttgcc gtctgactga
    12421 ggaaatcctc tgttaacaca atatcagtgt gattaaactg cgcaggggca tgcttgcgga
    12481 atttatccat aatctgtttg atttcagctg cgccatcaac accagacagt gtaacagaaa
    12541 tggttttttc tgcaaagtag ccgtattctt tgtaaatgtc atcaatacca tcagcaaggg
    12601 ttagtccacg agagcggtag taggcagcaa tctcagccac caatagcacc gcttgaatag
    12661 cgtccttatc acgtacaaat ggtttaatga gataaccaaa gctctcctca aagccaaaca
    12721 tataggtgta attgtgcttt tcttcaaatt cttgaatttt ttcagcaatg aacttgaagc
    12781 ctgttaagac attaaacatg gttgccccgt agctctctgc aattttagtc actaattcag
    12841 tagagacaat ggatttggca agagcggcat tgttaggtag ggttccagcc tgctgatgtg
    12901 cttctaaaat atacttagca attaaagcac caatttggtt gcctgatagg ttgcgatagc
    12961 tgccatctgc ctgccgaatt tcaaccccaa gacggtcagc atctggatca gtagcaacaa
    13021 gaacatcagc atcaacctga cgtccaagct cctcagcaag agtaaatgcc tcttgacttt
    13081 caggattagg agatttgacg gtagaaaaat ctggatctgg cttagcctgc acctcaacca
    13141 cctgaacgga cttaaagcct gcttgtgcca aggcacgacg tgctagcatt tcacctgttc
    13201 catgaagagg tgtatagaca attttcatgt cacgaccata gtcattgatg aggtcttggt
    13261 tgatattgac ctttttgacc tcttctaaat aagcaaggtc aacagcttca ccaataacct
    13321 cgatgagccc attagctttg gctttctcta aatcagcaag cctaatggca aaggggttat
    13381 caatcgcacg aatgtaatct gttagagcgt cggcgtcagc tggaggcatt tgaccgccgt
    13441 cagacccata aaccttatag ccgttgaatg gtgcagggtt gtgactggca gtaaccatga
    13501 taccggcaaa agcacccaaa tgtcgcacag caaaggaaag ctcaggtgtt ggccgaaggc
    13561 tttcaaaaac gtatgattta atgccatgag ctgctagtac ctgtgcagat tcaaaggcaa
    13621 attctggaga aaaatgacga gaatcatagg cgatagcgac accggccttc ttagcagctt
    13681 ctccctttga ctcaactaat gctgccaagc cctcagttgc ttggcgaaca acaaaaatat
    13741 tgatacgatt cgttccagcg ccaatatagc cacgcatacc agctgttcca aattcaagat
    13801 tggtgtagaa ggcatcttcc tttgtttttt cgtccatgct aagtaattca tctcttaaat
    13861 aggctggtag atctggaata tcaagccatt tttgatagtt ttctgtgtaa gtcatagtat
    13921 tctcctttat atttttaacc gctttcatta tatcatgttg aaaaggaaaa atcacttatt
    13981 ttctgtaata gcttccaatc attttttcac ataaggatca atttcctt
//
LOCUS       DARYUW010000052        13213 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYUW010000052 DARYUW010000000
VERSION     DARYUW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            304..1848
                     /locus_tag="TVW11_001537"
     CDS             304..1848
                     /locus_tag="TVW11_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1365624.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1932..2960
                     /locus_tag="TVW11_001538"
     CDS             1932..2960
                     /locus_tag="TVW11_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1365625.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            2981..4771
                     /gene="uidA"
                     /locus_tag="TVW11_001539"
     CDS             2981..4771
                     /gene="uidA"
                     /locus_tag="TVW11_001539"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1365626.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            4813..5484
                     /locus_tag="TVW11_001540"
     CDS             4813..5484
                     /locus_tag="TVW11_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1365627.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            5667..6284
                     /gene="eda"
                     /locus_tag="TVW11_001541"
     CDS             5667..6284
                     /gene="eda"
                     /locus_tag="TVW11_001541"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1365628.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            6312..7709
                     /gene="uxaC"
                     /locus_tag="TVW11_001542"
     CDS             6312..7709
                     /gene="uxaC"
                     /locus_tag="TVW11_001542"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1365629.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            7971..9065
                     /locus_tag="TVW11_001543"
     CDS             7971..9065
                     /locus_tag="TVW11_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1365630.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            9081..9920
                     /locus_tag="TVW11_001544"
     CDS             9081..9920
                     /locus_tag="TVW11_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1365631.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            10184..10987
                     /locus_tag="TVW11_001545"
     CDS             10184..10987
                     /locus_tag="TVW11_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1365632.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            11102..12892
                     /locus_tag="TVW11_001546"
     CDS             11102..12892
                     /locus_tag="TVW11_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1365633.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         3607 a         2449 c         3240 g         3917 t
ORIGIN      
        1 gttggtgggg tgacgatact gacctcaaag gggttggata agtattggta aaaggcttga
       61 gctctgtctt gtgcagggct cagttttttt gatgtcaatg agtaattgtc tgatgattat
      121 ttttaaagac accagaaatt atcagatgaa tttaatgatt aaaatcctaa ataagcttta
      181 ttttttaaaa ttaggcgaaa aaagtttaaa ttgtgttgac aaatcatcag atgaatagta
      241 agataagcat gtagaaataa aacgcttaca caataagcga atgataaaag ggggatttct
      301 ctgatggaga aaacaattga ccaaagggtt gaagaggtta cctataaccg cgctaaggtt
      361 tggcagcttg ttttatttgc tttaaacaat gcttcaacca atatctacct attcacattt
      421 atgtttgtga cctacttttc aacaggtgtt ctaggcttgg cagctatttt tgtcagccag
      481 atcatgggtt atattcgtat ttttgatggc tttattgatc ctgcgattgg tatcttgatt
      541 gataaaacag aaactaagtt tggtaagtat cgtccgatcc taatcatcgg aaatattatc
      601 acagccctat cacttattct gctgcttggt ctaagtggag ttagtgagaa cattcgtttt
      661 ccacttttta ttctggtttt gattatccat aagatcggct actctatgca gcaaaccatc
      721 actaaggctg gtcagacagc ccttactaat gatccgaagc agcgtccaat ctttaacatt
      781 gttgatgcca ttatgacaac cttgctgatg actggtggac agtttgttgt gtcaagcttc
      841 ttggttccaa aatttggtaa cttcacacca gccttcttcc acgtgttgat ttatggcacg
      901 attgttatct cagctatttt gggtctattg gcagtgcttg gtatttggag caaggacaga
      961 aaggaattct ttggtcttgg tgaaaatacg caaaagacag ctctgaagga ctatttgaag
     1021 gttatcaagg gcaaccagcc gctacaggtc ctatcaattg ccgcagcctt ggttaagttt
     1081 gctgttcaat tctttggtga ttcggttgtc atggttatct tgtttggtgt tttatttggt
     1141 aactatgctt tgtctggtca attctcattg ctgtttattg ttccggggat tttgattaat
     1201 attgcttttt caggtattgc tcgtaagaga ggtttgcgtt tctcatatat cagagctctt
     1261 cagattggct tggttggctt gttagccttt ggtattgtgc tctttatggg taataaaggg
     1321 gatctcagcc taagtcatat taacctttac actattttgt ttactgtgac actgattatt
     1381 gctcgctatg cctcacaagc gcctgctagc ttggtgctaa caatgggagc tgatatttca
     1441 gactacgaaa catcagaatc aggccgttat gtctcaggaa tgattggtac aatcttctcc
     1501 ttgactgact cgattgcatc atcatttgcg ccaatggtta ttggtgcagt gctggctggt
     1561 attggttttt caaagactta cccaacgatt gagacaccgc ttaccccaag tctaaagatg
     1621 gccttgattg cgctgcatgt cggtattcca tttgtagcct tactagtggc tttgattttg
     1681 atgtcattct acaagcttga caaagaggaa atggtgcgta ttcaagagaa gattcaagtg
     1741 atgaaagcaa gctctgataa ggaacgcgtg caggctatcg ctaaaaatgt accactgtca
     1801 gacatggact atgttgatgt gacaaaatat cctgttgata aggattaggt gctgggtcag
     1861 ctatttcttt gaggagtggc tgactttttt ataaaataat agagtagctt gatagtataa
     1921 ggaggaatgt tgtgaaaaaa gttgtatcct tgggtgaaat cctcttgcga ttgtcacccc
     1981 ctcaatacca gacgttaaag caggcaacaa gcctagattg tcaatttgga ggttctgagc
     2041 ttaatgtcat ctcaagcctt gctcagctag ggcatcaggt ctctcttatt tcagctattc
     2101 cagacaatga tctgggacaa atgacaaaaa cctttctctt ttcgcgtcaa attaatcagg
     2161 agcatattat cgaaaagggt cagcgtttag ggctttatta ttatcaaaag ggcttttctt
     2221 tgcgagcaag tcgggttacc tatgaccgct gtcattcagc cttttgggag tcaaagcgtg
     2281 ctgactatga tttggagcat gtttttgatg aggctgattg gtttcatgtg tctgggataa
     2341 cgcctgctct aacgagtgat ctttatgagc tgacctatta tttgatgaca aaggctaggg
     2401 cagagggatt gactatttcc tttgatttga attttagggc tagtctatgg tcctcctttc
     2461 aggaggctag agatctcttg tcgcctcttg ttcagctggc tgatgtttgt attggcattg
     2521 agccgctgac gcttaaggga agcggcgcgc ttgatttaaa ggatcaatta ggcttgaata
     2581 gaccctatga tgatgaagcc ttgttgaagg aggtgctggc taggttagct gatacctatg
     2641 gggtaaaatg ctttgccttt acccagagag agatggacta taccaatgaa tacctgttaa
     2701 aggcctacct gtatcaaaat ggcagccttt ataaaaccca aaaatctggt attcaggttc
     2761 tggaccgagt agggacgggc gatgctttta cggcagggct gattcatggc ttattaagtt
     2821 ataaagacga gcaggctact ttagatgttg caatggctag ctttaagttt aagcatacca
     2881 ttgagggtga tagtaatatc atgacacaag atgacattga tcatttactg gccaaggaat
     2941 cgcatgagat tcaacgataa tgtgataaag gagaaatcgt atgttatacc caatactgac
     3001 aaaaacaaga aagatttatg atttaggggg gctctggcaa tttaagctag gagaccataa
     3061 cccgcaggag ctcctagcct ctgatgagct gatggttgtg ccgacctcct ttaatgatgt
     3121 ggttgtggat aaggacaagc gcaattacat cggtgatttt tggtacgagc gctttgttga
     3181 tgtgccagat cttgctgctg atgaggagct ggtacttcgc tttggctctg tcacgcacaa
     3241 tgcaacagtc tatgttaatg ggcaagcttt agggcaacac aagggaggct tcactccatt
     3301 tgaggtgttg gtgcctgaga cccattatca ggataatcaa attaaggtat ctgtttgtgc
     3361 caataatatt ttagattata ccagccttcc agtgggcaat tatagtgaag aaactcaaga
     3421 ggatggcagt atcaaaaaaa ttgtcaagga gaattttgac ttcttcaact atgctggtat
     3481 tcaccgtcca gtgaagctta tggtgcggcc aaaatgccat atctcagata tcacgatcac
     3541 gagtgacttg tctgaggata tgacatcagc cttagtcgag gtatctgttg aaacctcagc
     3601 agctgttgat gaggttaagg tgacgatctt tgatgaagag cacaagctcg ttgcgcaggc
     3661 tattgatggc aaggcaagac ttgataaggt tcgtttatgg gaagttttag atgcttatct
     3721 atacactgcc cacgttgaga tcatcgtaga tggcaatgtt gtagatagtt atgatgagcc
     3781 atttggtatc agaagtattg cagttgaaaa aggacaattt ttactaaatg gcaagcctgt
     3841 ttatttcaag ggctttggta agcatgagga tacctttatc aacggtcgtg gattgaatga
     3901 agcagctaat ttaatggata tgaatctgct caaggagctt ggtgccaatt catttcgtac
     3961 ctcacactac ccttactctg aggagatgat gcgtctggca gatcgtatgg gaatcttggt
     4021 tattgatgag gttccggcag tagggctctt ccaaaacttt acagcctcct tggatctttc
     4081 gccaaaggac aatggcactt ggtctgtcat gaaaactaag gaagcgcatg agcaagcaat
     4141 tcgtgagctc gtcaagcgtg acaaaaatca cccttctgtt gtcatgtggg tcgtggccaa
     4201 tgagcctgcc agccatgaag agggagcaca cgaatacttt gagccgctga ttgctcttta
     4261 taaggcacta gatccgcagc agcgtccagt aacattggtt aatctgctat tagcaacacc
     4321 tgatcgagat aaggtgatgg atctggttga tgtgatctcc ttaaaccgtt attatgcttg
     4381 gtatgttgat catggagact tgatcaaagg agaggttggg ctgcgtcagg agctattaga
     4441 atggcagaag aagtttccta acaagcctat cctgatgaca gagtacggtg cagatacgct
     4501 tcctggtctt cattcgatgt gggatattcc atatacagag gaatttcagt gccgcttcta
     4561 tgagatgagt caccgcgttt ttgatgagat tcctaatcta gttggagagc aggtatggaa
     4621 ttttgctgat tttgaaacta atctgatgat cttccgtatt caaggcaatc ataaggggct
     4681 tttttctaga aatcgccagc ctaagcatgt tgttggtttg tttaaagagc gctggaatac
     4741 cattccccac tacaattata aaaagaaata gtgtacaata gtagctagca ataagtagga
     4801 agaagggatt gtatggctag gcctttagtc gaaaaaacag cagagcgctt gttaaagcta
     4861 attttagaac gtgggtatga ggttggagca aagctcccca atgaatatga gttagcacag
     4921 gacttagagg ttggaagaag cactattaga gaagctgtta gaagcttagc aactagaaat
     4981 gttttagagg ttagacaagg atcaggtact tatattagct cgaaaaaagg tgtttctgag
     5041 gatcctttag gcttttcctt agtcaaggac acagccaagc tgaccgctga tttgtttgaa
     5101 ttgcggctat tgcttgagcc taggattgcc gctttgacag cacagcatgc aacgccaaag
     5161 gaggttgaag ccttagagaa gcttgttgtt gatattgaag aggccgtagc tgctggtgat
     5221 cctaagcatt tgcagctgga tgtgaatttc cattccttga tggcaaaata cagtggcaat
     5281 attgctatgg atagcttgct accggtgatc aatcagtcga ttcatctgat caatgccaat
     5341 tacacaaatc gtcagatgaa agaagattct ctacaagccc acagagatat tctgaatgcg
     5401 attaaagcgg gagatccgat cgcggcacat gacgctatgc tcctgcacat catgacagtt
     5461 aagcgaacgg cttttctatc ataagcttaa gcttgcttgc cggaaacagt ctattgagtt
     5521 ttgagtgatt tgcttcttgg ctcgaataag agggcttggt tttagagata ctagaaccaa
     5581 gtcctttttt tgctttttcc ttgacaaatc atctgatgat ttatataata aaactaagac
     5641 aacggtttca tgaaaaggag gagcctatgc taaaccgatt aaaagagaat tatttttttg
     5701 ctattattcg tggaaaaaca gtagaagacg ctattgccat tgctaagcat gctattttag
     5761 gcggtattcg taatatcgag attacctatt ctactccaaa tgcttcagag gttattagaa
     5821 tattgtcagc tgagtttgag catgatgatg ctgtgattat tggagctggg acagtgatga
     5881 cgcctgatct ggcaagagaa gctattgcag caggtgctag ctttttagtt agtcctcatt
     5941 tttctagaga aatagcagag gttgccaatc aggcatcaaa tctttatttc ccaggctgtg
     6001 caacagctac tgaaattgtc acagcaatga atgcctcttg tccgattatt aaggtctttc
     6061 ctggaggtgt tgtaggacca ggctttatta aggatattca tggtcctatt cctgaggttg
     6121 atttgatgcc atcaggtggt gtgtcgattg acaatgtcaa ggagtggaaa aatgcaggtg
     6181 ctgttgctgt tgggattggt tcagccttag ctagccgagt tgaggctgag ggctatgata
     6241 gtgtaacccg tattgcagcg tcatttgtat cagcccttga ttaagggaat tggtcataag
     6301 aggaggacga gatggctttt aatgacgaca attttatgct aaaaaatgag gcagcaaagc
     6361 gcctctatca acaaatcaag gatcagccta tttttgatta ccattgtcac ttagatccaa
     6421 aggaaatttt tgaggacaag gtttatgaca atattgttga cctttggctt ggtggtgatc
     6481 attacaagtg gcgcttgatg cgcgctaatg gcatttcgga agaagaaatc acaggctcag
     6541 cctctaagct ggataaattc aaggcctttg cccgtacact tcagcgctcc tatggcaatc
     6601 ctgtttacca ctggtcagtg atggagttga aaaatgtctt tggtgtctgt gagctactga
     6661 ctgaggataa tgcagaggaa atctatcatc gtatcaatgc ttacttggtt gagcaccaga
     6721 ttagtcctag aaagttgatt gcagatagcc gagtgcggtt tattggtacg acagatcacc
     6781 cgcttgatga cctagcttgg cataagaggt tagctgctga tgataccttt gagacggttg
     6841 tcgcgccaac ctttagacca gatgaggctt ttattgagca tcagcgcttt gcagattttg
     6901 tggctcgtct tgctcaagct accggaagaa ctattacaga ttttaagagc tttatagcgg
     6961 ctatggaaga gcgtattgcc tattttgcag aaaatggttg taaggccagt gacatcagct
     7021 ttacagagat tgtctttgaa gcagcagagc cagagcaatt agaccgtctc atgacaaggg
     7081 ttttagaggg ctatcagccg cagccgttag aggtcaagca atggcagaca gcggtgtttg
     7141 cagagctttg caggctttat aagcactatg gctttgttac tcaggtgcat tttggtgctc
     7201 ttcgcaataa tcattcagct atattcaaca agctgggggc agatgtgggt gttgactcac
     7261 tgggagacca aacaggacta gcaatcaata tgaatcgcct gctggatcat ctggtgcaaa
     7321 gagacagcct gccaaagatg atttggtata acctaaatcc gagctataat atcgcggttg
     7381 ctaatacact agctaatttc caagccaatg aaaacggtat tgcgggctat ctgcaattcg
     7441 gtgcaggctg gtggtttgct gataccaagc ttggtatgat tagccagatg aatgccttgg
     7501 ctgagcaagg tttgttagct aattttgtcg gcatgctaac ggattcacgt tcatttttat
     7561 cctatcagcg tcatgattat ttcagacgta ttttgtcgac ctaccttggt gagtggattg
     7621 aagaaggtga ggtaccagag gattatcagg cacttggtaa aatggctcag gacattgcct
     7681 acaataatgc tatccagtat tttaactagg ctgccttggt cgttaactag aagaagcata
     7741 gaaatatgat gttgctctat gattaaggtc ctagtcttaa aagaggctag gacaatatcg
     7801 gcctgctagc tgctgtcggc gtcttgttga ttgactagat tacaaaggct agaccaagta
     7861 gcaggcccag gccctttagt tgcaagggta ttagccccaa aaacaataat aaataacaat
     7921 tgtgtgaatc gaaaggaaaa ggagtttacg agaactcgag gtatgatact atgaaaatgt
     7981 cgtttcgctg gtatggaaag catgatccag taagtttaga ggaaatcaag gccattcctg
     8041 gtatgcaggg aattgtaaca gctgtgtatg atgtaccagt tggtcaggct tggccactag
     8101 aaaatatcct tgaattgaag aggatagttg aggctgcagg ccttgagatt tcagtcatcg
     8161 aatcaattcc tgttcacgag gacatcaagc aaggaaagcc caatcgtgat gagctgattg
     8221 aaaattataa gacctctatc atcaatgttg gtaaggcagg tattcctgtg gtttgctata
     8281 attttatgcc agtgtttgat tggactcgct cagatcttaa ttacccattg cctgatggat
     8341 caacctcact tgctttttta aaggcagact tggcagatgt ggatcctgtg gcagatgatt
     8401 tgaacctacc gggttgggat ttttcttact caaaagaaga gatgaaggct attattgagc
     8461 attatcgtca tcatatttcc gaagaagacc tgtgggctaa tttagattat tttattaagg
     8521 ctattatgcc aacagcagag gcagctggcg ttaagatggc tatccaccct gatgatcctc
     8581 cttatggtat ttttggctta ccacgtatca taacaggtca aaaggctgta gagcgcttct
     8641 tagaccttta tgattcccct aataatggga ttaccatgtg tgtgggctcc tatgcttctg
     8701 atcctcaaaa tgatgtgatc gctatgacgg agtacgcgct taagcgccag cgtattaact
     8761 ttatgcatac gcgtaatgtc actgctggtg attggggctt ccaagaaacc gctcacttgt
     8821 cacaggctgg tgacattgat atgaatgcta ttatcaaatt attggttgat tatgactggc
     8881 aaggaccact tcgtccagat catggtcgtc gtatctgggg agatcaaacc aaaacccctg
     8941 gctatgggct gtatgaccgg gcacttggtg cgacctattt taatgggctt tatgaggcta
     9001 atatgcgtgc agctggaaag ataccagatt ttggcattac tgtaaaaaca gttggagata
     9061 aatagaaaaa ggggcatgag atgagtcgag ttattgaatt taaggacaag gttgttgtga
     9121 tcacaggagc tggcggtgtc ctttgtggca gtatggcaaa ggcatttgca aaagcagggg
     9181 ctaaggtggc actgttagac cttaaccaag aggcggcaca ggcctttgtt gatgatattg
     9241 aggcagaggg tggtattgca aaggcctatc aggcaaatgt attgtctaaa gaaaacctag
     9301 aggccgttcg tcaggcagtt ttagcagatt ttggtccagc agatatttta gtgaatggcg
     9361 ctggcggaaa cagccctaag gcaacaaccg ataatgagtt tcacgacaca agcctgccag
     9421 aggatacaaa aaccttcttt gaccttgatg aagcaggtat cagctttgtc tttaatttaa
     9481 actatttagg caccttgttg ccgacgcaag tctttgctca ggatatggtt ggtcgtaagg
     9541 gggcaaatat tattaacatt tcttcaatga atgcctttac gccattaaca aagatcccag
     9601 cctattctgg ggctaaggca gccatttcca actttaccca gtggttggct gttcattttt
     9661 ctaaggttgg cattcgttgt aatgccattg ctcctggatt tttggtaacc aatcaaaacc
     9721 gtagcctcct tttcacagag gacggacagc caacggctcg tgctgaaaaa atccttaaga
     9781 atacaccaat gggacgcttt ggtgaggcag aagaattaat tggaggcctc tttttcttgg
     9841 ctgatgagca gtctgcttcc tttgtgaacg gcgttgttct gccaattgat ggcggatttg
     9901 cagcttattc aggcgtctaa gctaaaaaat aaaccacttg agaactcaaa ctgcaatgcc
     9961 tcaagtggtt tttctatcgt gacagcttgc tttgtagcca agctgccatt aataaaggta
    10021 tgatgatttg tggcttctat tgttccttat cactctagcc ttttttagca atcaacaagt
    10081 aatgatagct tttaaaaatg aaacgctgct tgattaggat ttatgattga cagcgttttc
    10141 ttactgtgtt agaattaatt catcagatga tttggaggtt ggaatgacag ctaaaactga
    10201 acaatttgtc ttttgtgtgg actcagatgg ctgcgcaatg gacaccatga cttataagca
    10261 tcagctcttt tttggtccgc ttgcggcgga ttattttgcg gtagcagacc aagcgtcttt
    10321 cttaaaagag tgggatcgca ttaatcttta ttcgcgtaca cgcggtgtta accgctttgt
    10381 tgggcttgtt atggggctag aatacgcagg agttacaggg attgacgctt taaagcaatg
    10441 ggtacaacac actgcctcat tatccaatca gtctctggag gcggagcttc ttaagcgtcc
    10501 tagtgatgac ctgcaaaagg ccttggactg gtcaaatgag gtaaaccgtc agattgaggc
    10561 ctacaaagga gaggcattgg catttctagg agctttagct gctcttaagg ccttgcacca
    10621 gcttggccag gtttttgttg tcagctcagc taataaagag gccgttcaaa aggaatggca
    10681 ggatcaaggc ctgatgacac atgttgatgg cttgtattgt caggatcgtg gcaaaaaaga
    10741 ggctgtcata gcacagctca ttgatgaagg atatgtgaga gagcgcatga tgatgatagg
    10801 agattcacca ggtgatctag cagctgctga gcaaaaccag atcacttttt ttccaatcct
    10861 cgttggtaag gaggctagct cgtggcagga tctgtcacat gctgctgaag cttttacaac
    10921 tggtgacttg acagagcttg atgtcaagag ccttacagaa gccttctggc gtaatcttga
    10981 taggtaggca ggtagctgac cagtggagct gagcctgtta gggcttggta gcaggttgct
    11041 gtagcgccat tcattaaaac agaaaagcaa gcagagaagg ctttagttga aaggaagtac
    11101 aatgacacat ttagtagatt taagaaaaaa accatatagc ctagacgaag aagctatttg
    11161 ctgggtggag gataccattg cagcaatgac cttggaggag aagataggtc agctatttgt
    11221 taatatgggg gctagtcgat cagaggatta tttaactcag gtgcttgagg attatcatat
    11281 tgcagctgtt cgctacaata aaggcatggc ttcagaaatt tgggatcaaa attatatttt
    11341 acaaaccaaa tccaagattc caatgctcat tgctgccaat acagaggctg gtggtgatgg
    11401 tgctgtcaat gatggcacta aggttggtga tgaaatcaag gtagctgcga caaacgatcc
    11461 taaatacgct tatgaaatgg gacggattgc aggactggaa gcgtcagctg ttggctgtaa
    11521 tgcctccttt gcgccaattg ttgatttgac gcgtaattgg cgtaatccaa tcattgctaa
    11581 tcgcaactgg ggggtaaatg ttgatcaaat cattgagctt tccaaagagt atatgaaggg
    11641 gattatggaa tatggtatca tgccctttgc caagcacttc cctggtgatg gtattgatga
    11701 gcgtgaccat catttgtcct ttgcctcaaa cccaatgacc aaggaggagt ggctatctag
    11761 ctttggacgt atttatggcg agcttgcaga ggctggctta cctggtatta tggcaggaca
    11821 tattcacctg ccaaatgttg aaaaggccat gcaccctgag cgtgagctag atgatatgct
    11881 tccagcctca cttaataaaa ccctcttaga tgagctgctg cgtggtgagc ttggctataa
    11941 tggtgctatt gtgactgacg cttcgcatat ggttgcgatg acagcctcaa tgccacgtcg
    12001 cttattgtta ccaacagcga ttgaggcagg ctgcgatctc tttttattct ttaatgaccc
    12061 agatgaagac ctacaatgga tgaaagaggg ctatgaggca ggaattttaa gtgacgaacg
    12121 ccttcatgac gcccttcgtc gtacgcttgg cttgaaagca aagcttggac ttcatcgctt
    12181 tgaaggacac cgagaagata ttatgctgcc taaggacaag gcgatggtct tgattaacac
    12241 accagaggct caagcaattg cagatgaggt tgccgacaag gccattaccc ttgtgaaaaa
    12301 caagcaggca gggattttcc cggtaactcc agagcgctac aagcgtgtgc tgattgttaa
    12361 cgtggagggc tataagggtg gctttggtgc tatgattgca ggacagaaga aacgggcctc
    12421 agacattgtc aaggaattgc tagaggcgcg tgggcatgag gtaactgtct gggaatcaac
    12481 cgaagagcga atcatgcagc taccagagga agagcgtgca gcggctattg ctaatgttta
    12541 tgcacaaaag cagccgattt caaacattac agagcattat gatttaattc ttaatttggt
    12601 ggacgtcaat tctggaggta cagttcagcg tattatctgg ccagctgcta agggaacacc
    12661 ggatcagcca ttctacgtcc atgaggtccc aacaatcgtt gtttcagttc agcatgcctt
    12721 tgcccttgct gatatgccac aggttggtac ttatattaat gcctacgatg gcaaggacaa
    12781 cactatgaag gctttggttg caaaattagc tggtgaatct gaattcactg gagtgtctcc
    12841 tgttgatgcc ttttgtggct tgattgatac ccagctatgg catagcttct gaggttgcta
    12901 caggataagt agaggcttta cgtgttctgc ggtgattgct ctgaatgatt taaaaagatt
    12961 tcaggataaa acctgttaat cagccccttg tagctgcaga aatagcccca taatccctgt
    13021 ggtggggagt tttatccgat atggagatga tagagcctgt taatcctaaa gaaaagctag
    13081 agggtcattc tagcttttct ttttgtgcct aatgctcaac cttgcttcag atgatagaca
    13141 agctataagc ttgttgataa gtgaaacaat tgaacagata atgtttttta gagatgatat
    13201 attaagaata att
//
LOCUS       DARYUW010000053        12930 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYUW010000053 DARYUW010000000
VERSION     DARYUW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12930
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVW11_001547"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVW11_001547"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1365634.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TVW11_001548"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TVW11_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVW11_001549"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVW11_001549"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1365635.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TVW11_001550"
     CDS             complement(3364..4059)
                     /locus_tag="TVW11_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1365636.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TVW11_001551"
     CDS             complement(4212..5615)
                     /locus_tag="TVW11_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1365637.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TVW11_001552"
     CDS             5997..6341
                     /locus_tag="TVW11_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365638.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TVW11_001553"
     CDS             6359..6754
                     /locus_tag="TVW11_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1365639.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TVW11_001554"
     CDS             6804..7925
                     /locus_tag="TVW11_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1365640.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TVW11_001555"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TVW11_001555"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1365641.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TVW11_001556"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TVW11_001556"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1365642.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TVW11_001557"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TVW11_001557"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1365643.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TVW11_001558"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TVW11_001558"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1365644.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TVW11_001559"
     CDS             11408..12799
                     /locus_tag="TVW11_001559"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1365645.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3787 a         2581 c         2858 g         3704 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcctgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt
//
LOCUS       DARYUW010000054        12720 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYUW010000054 DARYUW010000000
VERSION     DARYUW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12720
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            82..657
                     /locus_tag="TVW11_001560"
     CDS             82..657
                     /locus_tag="TVW11_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1365646.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKIENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPIHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            1006..1188
                     /locus_tag="TVW11_001561"
     CDS             1006..1188
                     /locus_tag="TVW11_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1365647.1"
                     /translation="MLTYDEFKQAVDNGYITGDTVTIVRKNGQILDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1386..1775
                     /locus_tag="TVW11_001562"
     CDS             1386..1775
                     /locus_tag="TVW11_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1365648.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1772..2983
                     /locus_tag="TVW11_001563"
     CDS             1772..2983
                     /locus_tag="TVW11_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1365649.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2996..4342
                     /gene="asnS"
                     /locus_tag="TVW11_001564"
     CDS             2996..4342
                     /gene="asnS"
                     /locus_tag="TVW11_001564"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1365650.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4643..5737
                     /locus_tag="TVW11_001565"
     CDS             4643..5737
                     /locus_tag="TVW11_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1365651.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEVGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGP
                     KGDRGEQGPKGERGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGER
                     GEQGPKGDRGEQGPKKEPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLP
                     STGDTSQSFVAAALGFIASAGLLVFKRKKN"
     gene            6263..7153
                     /gene="rapZ"
                     /locus_tag="TVW11_001566"
     CDS             6263..7153
                     /gene="rapZ"
                     /locus_tag="TVW11_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1365652.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            7150..8127
                     /locus_tag="TVW11_001567"
     CDS             7150..8127
                     /locus_tag="TVW11_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1365653.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            8124..9035
                     /gene="whiA"
                     /locus_tag="TVW11_001568"
     CDS             8124..9035
                     /gene="whiA"
                     /locus_tag="TVW11_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1365654.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            9395..10792
                     /locus_tag="TVW11_001569"
     CDS             9395..10792
                     /locus_tag="TVW11_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1365655.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            11032..12582
                     /locus_tag="TVW11_001570"
     CDS             11032..12582
                     /locus_tag="TVW11_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1365656.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         3753 a         2523 c         3025 g         3419 t
ORIGIN      
        1 agttttaaga aaggaggttt gttgacatat tggggtagca cttaatagtt tctctgttat
       61 taaaatagtt ggagaaaatt tatgaaaaaa gtaataaata ctattctatt agctgcttgt
      121 tttttattct ttttaggtaa ttttactaca aatgtattag ctgaagggat aaatgataaa
      181 atagaaaatg gcactgaaag cgatattagc ttccaaaatg gtgaactcct aaaaaattat
      241 cttatcctag aaggtgaacg agtatacttt gattatgata gagcaactca agataaagta
      301 tcagatgatg ttctagagat gggaatgtta gttgaagcta taagtaagga ttattctgag
      361 aagacattca ccccagataa atattttaaa gctagttggc ctatccatgg taactattgt
      421 ggaccaggtc ataatgggaa taactttacg ttgccagtag tagatgtttt ggatcaaggt
      481 tgccaaaacc acgatagttg ctataagtgg ggtgccggta ttggtgctaa ttgtgaatgt
      541 aaccgtcagc tcgttaatta cataaaagtt tatagacgat ggatgccagc gaatgtcctt
      601 ggcgtagccg atgctattag agtatatttt gagacagtag gttctatagg atgttaaatt
      661 tcaaaaaaaa cgttagtgat tattcgaagt actatatttt gagtatagtg ttattatgga
      721 taggaatgtt ctttgttcct tgggataaga ctctattcgg tgtttcgatt tatctgtttg
      781 ttatgcaaaa gttatttata gtgtttggtt tgacggctat cttcatggcc tttgtgtcta
      841 aaaaaataaa tctatttatt tggggaatat tatttatttt cgcattttgg attaatatgt
      901 ttttgttatt ttccgtatta ccaattttgg ggaattagtt taacaaaaaa gaagaggggg
      961 ggttctccct cttcttttac gaataaatag ataaggaggt gctttatgct aacatacgac
     1021 gaatttaagc aggcagttga taacggttat atcacaggcg acacagtcac gatcgtgcgt
     1081 aaaaacggac agattttgga ttatgtgttg ccgcatgagg aagtaaggaa cggggaggtt
     1141 gtgacagacg aaaaagtgga agaggtgatg agagaattag acaaataaaa aagacctcgt
     1201 ccagaagtcg gggaattgtc ggggacaacg tttgtaaatg tttctattcc aacataaaac
     1261 attttttgat ataataggaa ggatcatatg caaaggagct gaaattggac aagcacaaaa
     1321 ggctcaaaac agttttatat caatgtgcca gcttggtcgt actgctttgt cttggagtga
     1381 tgagcatgtt ttatcttgct gttcatgatc aatttgacaa gaaatcaagg ttagccgaga
     1441 tagcaaaatc aagagctggt gtcatctcaa ttgatcatat tgattgctat catggcactc
     1501 agagctacct cagtcttttt ggaaaaaaca aggcaggcaa taccatcatc gtcacaatag
     1561 aggagcaatc agagcagctc ttgcttagtc gccctagcaa tggcattagt gctaaggaag
     1621 cacaggaaat tgcctaccat gccggagcaa ggactattga agcagtgaca tttgggattg
     1681 aaaaccacaa gaggatttgg gaggtggctg ctcaaaacgg ctactatctg attgatttca
     1741 aaaccgcaaa agtgatcaaa aaggaggttt tatgaccaag ctatcaaggc gcgtgttagc
     1801 aatggaagaa agcgtcaccc tagcagcagg tgctagagca aaggcactaa aggctcaggg
     1861 acgcgatatt ttaagcctaa ctctgggaga gccagatttt ataacaccgc agcatatcca
     1921 agaaaaggcc attgaggcca tcaccactgg taaggcaagc ttttacactg ttgcttcggg
     1981 gttgccagag ctcaaggacg ccattgctga ttacatggca cgatcctatg gttatattcc
     2041 taccagacag gagattgtag tggggacagg cgccaaatac gttttgtatg cctttttcat
     2101 ggctgtttta aatcctggtg atcaggtgtt gattccgact ccttattggg tttcttatgc
     2161 tgatcagatt aaaatggtag acggggtacc ggtctttgta cagggcttgg aggaaaatca
     2221 atttaaggtc acagtagagc agctagaggc tgccagaact gatcaaacaa aggttgtttt
     2281 gatcaattct ccgtccaatc caactggcat gatttacagc cgacaggagc ttgaagccat
     2341 tggcaattgg gctgttcagc atgatattct gatcctggca gatgatatct atggtgcatt
     2401 ggtctacaat ggcaatcaat ttactccaat atcagcctta tcagaggcta ttcgtagaca
     2461 gaccattact gtaaatggcg ttgccaagag ctatgcgatg acaggctggc gtttgggctt
     2521 tgcggtcgga gacactgata ttatcgctgc tatgggtaag attatcgggc aaaccacctc
     2581 taatgtgaca acagcgtccc aatatgcagc gattgaggcc tttggcggtg accaaacgtc
     2641 agttgaggag atgagacagg cctttgaaga gcgcctcaat accatttatc ccctgctcaa
     2701 tcaagttcct ggctttgagg ctattaagcc ccaaggagcc ttttatttct ttcccaatgt
     2761 caaaaaagct atggagatga agggctttac cgatgtgaca gcctttactg atgcgatcct
     2821 agaagaggta ggactggctg ttgtcagcgg agctggcttt ggtgctccag aaaatatcag
     2881 gctaagctat gccactgatt tggcaaccct aaaagaagct atcagacgac tcaatcagtt
     2941 catgacaact gacagcagcc atgacaacaa agagaatgaa tagaaaagag acattatgac
     3001 caaaaaatac gtttccatta tcgatgttaa agaccatgta ggacaagaag tgacagttgg
     3061 tgcttgggtc gccaacaagt caggcaaagg gaaaatagcc tttttgcaat tgcgtgatgg
     3121 ctcagccttt ttccaggcag ttgcctttaa gccaaacctg atccaagcct ttggtgagga
     3181 agcaggagca gctaagtttg acacgattag gcatctcagc caagaaacct ctgtcttagt
     3241 aaagggcatt gtcaaagagg acgctagatc aaaatttggc tatgagctag acattacgga
     3301 cctagaggtt attggggatt ccaaggatta tccaattact ccaaaggagc atgggacaga
     3361 ctttctcatg gatcaccgtc acctttggct gcgctctcgc aggcaggcag caatcatgca
     3421 aatccgtaat gccatcatct atgcttccta tgagtttttt gatcaaaatg gctttatcaa
     3481 gtttgatagc ccgattttat caggcaatgc tgctgagaac acaacagagc tatttgagac
     3541 agattatttt ggcaatccag cctttctcag ccaatcaggt cagctatacc ttgaagctgg
     3601 tatgatggcg cttggtcgcg tctttgactt tggtccggta tttcgtgccg aaaaatcaaa
     3661 aacgcgccgc catctgacag agttttggat gatggacgca gaatacccct tcttatccca
     3721 tgaggaatcc ttagacctac aggaagccta tgttaaggcg atgattcagg gtgtgcttga
     3781 tcgtgctcca caggcattgg agcttctaga gcgtgacaca gagctgctga aaagatacat
     3841 tgcagagccc ttcaagcgtg tctcctacga cgatgcgatc agcctgcttc aggagcacag
     3901 cacagatgac gatgccgact atgagccaat tcagcatggc gatgactttg gctcaccgca
     3961 tgaaacctgg atttccaatt attttggggt cccaaccttt gtcatcaact acccagctag
     4021 ctttaaggcc ttttacatga agccggttcc cggcaatgaa gagcgcgtgc tatgtgcgga
     4081 cctgctagca ccagagggct acggtgagat tatcggaggc tcggttcgtg aggataacta
     4141 tgacaaattg ttggcgaaaa tcaaggctga aggcctaaat cctgaggatt atgactttta
     4201 ccttgacctt cgcaaatatg gctcagtgcc gcatgctggt tttggacttg gactagagcg
     4261 catggtgacc tttgttgcag gtaccaagca cattcgtgag gctattccat ttccacgcat
     4321 gcttcatcgc ttaaaaccat aatgaaccct atcagcgtcc gccattgggc gcttttttgc
     4381 tgcgctgagc agtacttaga gctcaagcct cccagttaga cttggcagag ctgtggctct
     4441 ttgcttgagc tattgtaggc aaaggtatca ctggatctga aaacaacaaa atcagacaag
     4501 tgatatcaaa attaaaaaaa aaaaaaaacg aaacctagga ggatcggtga gcttattagt
     4561 ttggcactaa tcatcattat gctataattg tcttcacaaa taatttagaa atagctcata
     4621 tttctatcat taaaggagag agatgatgaa tcgtaaaaag cataccaaac tcattcgtca
     4681 ctacagtatc tgctcagcag tggctgtcct agcagcagtt agcttgggaa caggtcagga
     4741 cgtacaggct tcggaaccca atccatatcc agatgtgagg cgtttccttg atgagaagta
     4801 cgatggagat gtggataaat tatctaaaca acttcaaggt tattttggta gtttaagaga
     4861 gtatatagag tttgaactta aaaatggcaa acaaggtcct gctggccctc aaggcccaaa
     4921 gggtgataaa ggagaccccg gagagccagg tcctcaaggt ccagtgggcc ccgctggtcc
     4981 aaagggtgat cgtggtttag acggacgacg tggcccagca ggtcagcaag gggaagtcgg
     5041 cccagttggt cctcagggtc ctcaaggcga gcaagggcca aaaggcgacc gtggcgaaca
     5101 aggaccaaag ggtgaacgcg gtgagcaagg accaaagggt gaacgcggtg agcaagggcc
     5161 aaaaggcgac cgtggcgaac aaggaccaaa gggtgaacgc ggtgagcaag gaccaaaggg
     5221 tgaacgcggt gagcaagggc caaaaggcga tcgtggcgag caaggaccaa agggtgaacg
     5281 cggtgagcaa gggccaaaag gcgatcgtgg cgagcaagga ccaaagggtg aacgcggtga
     5341 gcaagggcca aaaggcgatc gtggcgagca aggaccaaag ggtgatcgtg gcgagcaagg
     5401 accaaaaggt gatcgtggcg aacaaggacc aaagggtgat cgtggcgagc aaggaccaaa
     5461 aggtgaacgc ggtgagcaag gaccaaaagg cgatcgtggc gagcaaggtc caaagaagga
     5521 gccagaaaaa gacaccaagc catcagtgcc aaaggcacca gataatatgg ctgcaccaaa
     5581 ggctccggag aagaagaacc ctaaagcacc ggctcctaag tcagctccaa aggcatcatt
     5641 gccatcaaca ggagacacta gccaatcatt tgttgcagca gcccttggct ttatcgctag
     5701 cgcgggcttg ctagtcttca aaagaaagaa aaactaagct agctaaagac tgtaaacaag
     5761 cctcaactgt tacagcaagc ctctttgaca tcttgcagat aagaggattt cttagcgaat
     5821 gaagtgtgtc taaagtcaga tactctgctg gactagcagt agctgatctc cctgaaaatc
     5881 agttatgcta aagcattgag ccttagttgc aaggcttagg tgtgaccttc caaaggaagc
     5941 tgcttttgcc tgtatcactt taggaagata tctaaaagag acactttttt cacgctgaag
     6001 ctaagctagc ttttcctatg acaaatatcc tataacaata aactccaaac aaaagagagg
     6061 tcaaatggta cctctctttt acttagcttt aggattgata gattctaaag gcttccttgt
     6121 ttcttgatca agaagtcctt actgatagag tctgtcttag ccgggcttat atggtataat
     6181 acctaatgga gataagaaaa gtccttaaca aatagagttt catctattgt tacaggagca
     6241 accaagtgaa aggagatgct acatgtcaga taaacaaatc aatttggtta ttgttacagg
     6301 aatgagtggc gccggcaaaa cagttgccat tcaatcattt gaggatttgg ggtattttac
     6361 tgttgataac atgccaccag ctttagtgcc taaattttta gagctgcttg agaggaccaa
     6421 tgaaacccaa aaggttgctc tggtagtgga tatgcgcagc agacgctttt tcaaggagat
     6481 taactctatc ttagatcata ttgagctaaa tgccaacctc aagctacgga tcctctttct
     6541 tgatgcgact gatagtgagc tagtgtcacg ctataaggaa actagaagaa gtcaccctct
     6601 ggctgctgat ggtcgggtgc ttgatgggat tcgacgagaa agagagctgt tagtcccgct
     6661 taagagcatg agtcagcatg tggtcaatac caccgatcta accccaagac agctgcgtaa
     6721 ggtgatttcg gatcagtttt caagcgagtc agaccaagcc tcatttagaa ttgaggtgat
     6781 gagctttggc tttaaatatg gcctcccctt agatgcggac cttgtctttg atgtgcgctt
     6841 tttgcctaat ccttattatc aggtggcgct aagagagcag acagggcttg atcaggctgt
     6901 ttttgattat gtgatgactc atcaagagtc agaggccttt tataatcatt tgttaggctt
     6961 gattgttcct attttgcctg cttatcaaaa ggaaggcaaa tcagtgctaa ccattgctat
     7021 tggctgtaca ggtggtcagc atagaagcgt cgcctttgcc catcgcttgg cccaagactt
     7081 gacagcagac tggccgctgc atgagagtca tcgggacatc aatcgtcgta aggaaacggt
     7141 aaatcgctca tgagaaatcc taaaataacg gtgataggag gaggaacagg tattcctgtt
     7201 atcctaaaaa gccttcgcaa ggaggcggtt gacattactg cggtggtcac tgttgctgat
     7261 gatggtgggt catctggtaa gctgcgcaat gccatgcagc ttaccccgcc aggtgatttg
     7321 cgcaacgtct tgttggccat gagtgacatg cctaagtttt atgagcgtgt gtttcagtat
     7381 cgttttaatg aggcagatgg tgctctagct ggtcatcctc taggcaattt aattatcgca
     7441 ggtatttctg agatgcaggg atccacctat aacgctattc agattttgac gaaatttttc
     7501 catatcaccg gcaagatttt tccctcaagc gagcagccct tgacactgca tgctgtcttt
     7561 aaggacggtc atgaggtgtc aggagaaagc tctattgcca gctaccaagg catgattgac
     7621 catgtctatg tgaccaatac ctacaatgat gacctgccaa aggccagtcg taaggtggtt
     7681 gaggccattc tccaaagtga tatgattgtg cttggtcctg gttccttgtt tacctctatt
     7741 ttgcccaatc ttgtaattcc agagatcaaa gaagccctga gagtaaccaa ggcagaggtg
     7801 gtttatattt gtaacattat gacccagtac ggtgagacag agcaattttc cgatgcggat
     7861 catgttgcgg ttttaaatca gcatctgggc agggacttaa ttgacactgt tttggttaat
     7921 gttgagcagg tgccaaaaag ctatatgaat tccaaccaat ttgacgaata tctggtccaa
     7981 gtagagcatg actttgcagg tctgtgtaag accgcaaagc gtatcatctc gtctaatttt
     8041 ctgcgtttgg agaatggcgg agcctttcat gacgggcact tggttgtaga agaattaatg
     8101 aacctagtta ggataaccaa gctatgagtt ttacgacaac tgttaaagaa gaattgattc
     8161 atttatctgc ttctgatcaa acagaattat cagcaatcat caagctggct ggtagcctag
     8221 gcttggctaa tcagagcttg aatttgtcta tcacaactga aaacgctaag attgctcgct
     8281 acatctatgc gcttatcgaa gacacctatc atatcattcc agaaatcagg taccatcaaa
     8341 agaccaactt gaaaaaaaat cgtgtctata cggtttattt ggataagcag gtggataagc
     8401 tcttagcaga tttaaagctg gcagattctt tttttggcat tgagacaggt attgagcagc
     8461 aggtcatgtc agatgatgat gctggtcggg cctatctcaa gggtgctttt ttagcggcag
     8521 ggactgtaag ggatccagaa tccggcaagt atcagctaga gatctactct gtctatctag
     8581 accatgctca ggatttggcc cagctcatgc acaaattcat gctagatgcc aaggttatcg
     8641 agagaaaaaa tggtgcagta acctatttgc aaaaggctga ggacatcatg gattttctca
     8701 ttattattgg tgccatgtcg tgtaaggagg agtttgaggc tgttaagctt ttgcgtgagg
     8761 cgagaaatga catcaatcgg gccaataatg cagagactgc taatattgct aaaaccatca
     8821 ccgccagcat gagaaccatt aataatatta tcaaaatcat ggatacgatt ggcttagaca
     8881 gcctgccagt tgagctgcag cagattgccc agatgagagt agccaaccca gactattctc
     8941 ttcaacaaat cgcagattcg cttgactttg ccatcactaa gagtggggtc aaccatcgcc
     9001 tgcgaaaaat caataagctg gcagaggatt tataaagaca gcttagcctt tttcaggctg
     9061 ataaaaaagg gggtaaggtg atacgaacaa gccgcctttt aaggcatgcc ttgttgagct
     9121 ttctctaggc tgttgatgga gtgatctcaa ggcgcttttg ttactgtcat tccaacaggc
     9181 tatctgattt tgggatgact tcttactaat aagcttttct aatggctggc tgacaacgat
     9241 tagcgatata gttaaggctt atcgtgattc aacaagaggc tttagtctct tttttgcttg
     9301 tcagaattat ttttttaggc ttttcttaca aatgagagga caatgtgaca atctgtggta
     9361 tgatattagt aatgaataca aaggagaaca aatcatgtca tgcacaacta ttcttgtcgg
     9421 taaaaaagcg acctatgatg gatcaacaat cgttgctcgt acagaggatt cacaaaatgg
     9481 ggaatttacc cctaaaaaaa tgacagttgt tagaccaaaa gaccaaccta gacactatca
     9541 atctgtcttg tctagcttta gcatggagct gccggatcag ccgatggctt atacctcggt
     9601 gcctgatgcc ctaggaaagg acggtatctg gggagaagca ggtgtcaata ccctcaatgt
     9661 tgctatgtca gcaactgaga ccattacttc aaatgctcgc gttcttggag cagatcctct
     9721 tgtttcctct ggtattggag aagaggacat gctgaccttg gtgcttcctt atattcggtc
     9781 tgcaagagag ggtgttcttc gtttgggagc tatcctagaa gcatacggta cctatgaggc
     9841 taacggtgtt gccttttctg atgagcatga gatttggtgg ctggaaacaa taggtggtca
     9901 tcattggatt gcaaggcgcg ttcctgatga tgcttatgtc actaatccca accagtttgg
     9961 ccttgatcac tttgaattta acaatccaga ggaatacctg tgttccaagg atttaaagga
    10021 ctttattgcc aaatatcatc tagatttgac ctatagcaac gagcatttta accctcgcta
    10081 cgcctttggt agccaaagag ataaggatcg ccattacaat acaccacgcg cttggattat
    10141 gcagcaatac tttaatccgg agtttctgca ggatccgcgc agctttgaac ttccttggtg
    10201 ccaaagacct gatcgcaagg tgaccattga agacgttaag tacgtgctta gcaatcatta
    10261 tcaggacacc ccttatgatc cttacggccc agagggaacg ccgactagtc gaaaatcctt
    10321 taggccgatt ggtattaacc gtacgagtca aactgctatt ttacatatcc gtcccaacaa
    10381 gcctaaggaa attgctgcca ttcagtggat ggcctatggt tcgatgccct ttaatacaat
    10441 cgttccgcta ttcacccagg tcaagaccat tccagattat tttgcaaaca ctgttgaaaa
    10501 tgtttccaca gacaatttct attggaccaa tcgcttgatt gcagccctgg ctgatcctca
    10561 cttcaagcac catgaagcag atttggagga ctatctcgaa aaaacaatgg ccaagggtca
    10621 tgccatgctg catgctgttg aagcagcgct agtaaaaggt cagccggttg acctagaaga
    10681 ggccaaccaa ggcatgagtg atgacattca ggcagataca caggctctgc tcaataagat
    10741 cctctttgat gctagcaatc tcatgaccaa ccgctttagc ctaagcgact aagtaatctc
    10801 aatagtcaaa cgagctcata tcattataga tatgggctct tagcttgaaa aggatagtag
    10861 agcggtctta tagtcagact aattaatggt aacgatgagt ccagttaagg taaaaaaaga
    10921 gcacttagct aatgcaaaaa aagtaaaaaa cttgcaaaag aatgatattg tgttatactt
    10981 aaccagtaaa tattaagagc tatttgcgat atgatatata gaggaggaat catgaaaaag
    11041 aagtatcttt taatgatgag tgtgctcggt gtcttttttg cgggacagat cagtcaagca
    11101 aaacaggtcc tagcagatag taaggtcaaa attgttacca ccttctatcc tgtttatgaa
    11161 tttaccaaag gcgttgtcgg aggtgaggga aatgtgtcta tgctgatgaa agcaggaaca
    11221 gagcctcatg attttgagcc gtcaacaaag gacatcaaaa agatccaaga tgccgatgcc
    11281 tttgtttata tggacgataa tatggaaact tgggtccctg atatgaagaa atcactgact
    11341 tctaagaagg ttacggtgat taagggaaca ggagatatgc tattggtagc tggctctggt
    11401 cacagccacg agcatgacca tgacgatgcc gataaaaagc atgatcatga ccacgacgag
    11461 gaaggacaca gccatgcttt tgacccgcac gtatggttgt caccttatcg cagcatcacc
    11521 gttgtcgaaa caattcgtga tggtctatct aaggcctatc ctgacaaggc tgaccacttc
    11581 aaatctaatg ccgctgctta tattgaaaag ctcaaggaat tagataagga gtatagtgac
    11641 gctttttcag ctgccaagca aaagagcttt gtgactcagc acgcagcctt tggttatatg
    11701 gcgcttgatt atggcttgaa ccaaatctca atcaatggtg tcacaccaga tacggagcct
    11761 tcagctaagc gcattgcaga gctatcaaaa tacgtcaaaa aatatgacat taactacatt
    11821 tattttgaag aaaatgcttc aagcaaggtt gccaaaaccc tagccaagga ggctggtgtc
    11881 aaatcagctg tccttagtcc gcttgaaggc ctaactgaaa aggacatgaa ggccggcaag
    11941 gattacttta ccgttatgcg tgaaaacctc aaaaccctac gcttaacaac tgatgtagaa
    12001 ggaaaagaaa ttcttccaga agaggatacc actaaaactg tttataatgg ctactttaag
    12061 gataagcagg tcaaagaccg caaattgtct gattggtctg gtaactggca gtctgtttac
    12121 ccattccttc aagacggtac attagatcag gtatgggact ataaggctaa aaaatctaaa
    12181 ggaaaaatga ccgcagctga atacaaggat tattacacca ctggctatca gacagatgtc
    12241 agtcatatca agattaatgg taagaaaaat accatgacct ttgttcgtaa tggtgaaaat
    12301 aaaaccttta cttataagta cgtcggtaaa aagattttga cctatccaaa gggcaatcgt
    12361 ggcgtgcgct tcatgtttga agctaaggag ccagacgctg gtgaatttaa atatgttcag
    12421 ttcagtgacc atgctatcgc accaggtaag gcggagcatt tccacctata ctggggtggt
    12481 gacagccaag aaaagcttca caaagagcta gagcattggc caacttacta tgatgcggac
    12541 ctatcaggtc gtgccgttgc ccaagaaatc aatgctcatt aaccactcaa aagactaggc
    12601 agttcaatcg gcctagtttt ttcttgtctt agttgctgta taggacctaa atgctgatag
    12661 ctggtcttaa gatttatttt taatttttct aactatattt aggttgtatt tgtttgttaa
//
LOCUS       DARYUW010000055        12203 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYUW010000055 DARYUW010000000
VERSION     DARYUW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12203
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(81..1361)
                     /locus_tag="TVW11_001571"
     CDS             complement(81..1361)
                     /locus_tag="TVW11_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1365657.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVW11_001572"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVW11_001572"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1365658.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPVARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TVW11_001573"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TVW11_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1365659.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TVW11_001574"
     CDS             6342..6845
                     /locus_tag="TVW11_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1365660.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TVW11_001575"
     CDS             7344..8537
                     /locus_tag="TVW11_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1365661.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TVW11_001576"
     CDS             complement(8736..9200)
                     /locus_tag="TVW11_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365662.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TVW11_001577"
     CDS             9468..10316
                     /locus_tag="TVW11_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1365663.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TVW11_001578"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TVW11_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1365664.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TVW11_001579"
     CDS             11592..12071
                     /locus_tag="TVW11_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1365665.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..>12203
                     /locus_tag="TVW11_001580"
     CDS             12068..>12203
                     /locus_tag="TVW11_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365666.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     G"
BASE COUNT         3668 a         2691 c         2355 g         3489 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcaa cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat gcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcg
//
LOCUS       DARYUW010000056        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYUW010000056 DARYUW010000000
VERSION     DARYUW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(152..433)
                     /locus_tag="TVW11_001581"
     CDS             complement(152..433)
                     /locus_tag="TVW11_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1365667.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TVW11_001582"
     CDS             complement(466..1233)
                     /locus_tag="TVW11_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1365668.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TVW11_001583"
     CDS             1352..2092
                     /locus_tag="TVW11_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1365669.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TVW11_001584"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TVW11_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TVW11_001585"
     CDS             3072..5315
                     /locus_tag="TVW11_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1365670.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TVW11_001586"
     CDS             5428..6489
                     /locus_tag="TVW11_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1365671.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TVW11_001587"
     CDS             6567..7172
                     /locus_tag="TVW11_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1365672.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TVW11_001588"
     CDS             complement(7423..8637)
                     /locus_tag="TVW11_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1365673.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVW11_001589"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVW11_001589"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1365674.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TVW11_001590"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TVW11_001590"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1365675.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TVW11_001591"
     CDS             10819..11535
                     /locus_tag="TVW11_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1365676.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TVW11_001592"
     CDS             11627..>12157
                     /locus_tag="TVW11_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1365677.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3304 a         2348 c         2831 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacgata atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYUW010000057        11968 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYUW010000057 DARYUW010000000
VERSION     DARYUW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11968
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..397
                     /locus_tag="TVW11_001593"
     CDS             <1..397
                     /locus_tag="TVW11_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365678.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TVW11_001594"
     CDS             441..1106
                     /locus_tag="TVW11_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365679.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TVW11_001595"
     CDS             1103..2080
                     /locus_tag="TVW11_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1365680.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TVW11_001596"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TVW11_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1365681.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TVW11_001597"
     CDS             complement(3407..3844)
                     /locus_tag="TVW11_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1365682.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4045..4737
                     /locus_tag="TVW11_001598"
     CDS             4045..4737
                     /locus_tag="TVW11_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365683.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5113..5589)
                     /locus_tag="TVW11_001599"
                     /pseudo
     CDS             complement(5113..5589)
                     /locus_tag="TVW11_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TVW11_001600"
     CDS             complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TVW11_001600"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1365684.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7651..8349
                     /locus_tag="TVW11_001601"
     CDS             7651..8349
                     /locus_tag="TVW11_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1365685.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8561..8893
                     /locus_tag="TVW11_001602"
     CDS             8561..8893
                     /locus_tag="TVW11_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1365686.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8908..10479
                     /gene="ffh"
                     /locus_tag="TVW11_001603"
     CDS             8908..10479
                     /gene="ffh"
                     /locus_tag="TVW11_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1365687.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10632..11855)
                     /locus_tag="TVW11_001604"
     CDS             complement(10632..11855)
                     /locus_tag="TVW11_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1365688.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
BASE COUNT         3776 a         2269 c         2220 g         3703 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgaccgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatgt ttggcattaa acctaagaca gcttactgtc ttttcgatat aaacataaaa
     3961 agcttgaata ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta
     4021 tactgacaaa ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta
     4081 tcaaggcata ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt
     4141 tccaattggg aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc
     4201 atttttcaat tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt
     4261 cagttaagcg cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa
     4321 aaagaaaaaa taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat
     4381 gaaaggttgt ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc
     4441 ttttacgatg agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag
     4501 ccaacctatt tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt
     4561 gctatctatg ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa
     4621 aatggtctgc gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat
     4681 gacaatccgc gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc
     4741 tttgtattag cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc
     4801 attatttttg aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta
     4861 aaggtttttg aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg
     4921 gtggtttatt tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac
     4981 atcgctaaaa gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata
     5041 tgcttgatta accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa
     5101 tccaaataat cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg
     5161 cagtttattt ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc
     5221 tttttcttta tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat
     5281 attatcgtaa ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgactaaa
     5341 tatgtatctc cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac
     5401 attattccag aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa
     5461 aatatcagta atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat
     5521 tatgattttc tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc
     5581 ttcaatcaac caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg
     5641 aaggctttta aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct
     5701 ttttagtatc aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca
     5761 ctgttttcaa cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt
     5821 gctggtggtt tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca
     5881 attcgaactg agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata
     5941 ccatcaattg aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc
     6001 ataactccga cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca
     6061 agtcctgctt tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc
     6121 ttttctgctg tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga
     6181 cgccagacga cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta
     6241 aagagtgtat tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca
     6301 ttgtggtgag attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa
     6361 agcgttcctt gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg
     6421 taaacaaact cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga
     6481 agatctaaaa agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca
     6541 agcatttcca taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata
     6601 caggttaatt gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca
     6661 ccaccagaca aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt
     6721 tgcatgtcaa taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca
     6781 aagttcttca aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata
     6841 ccgtagagcc tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct
     6901 acaagatgaa agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc
     6961 tgctcatctg gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga
     7021 ccatattctc ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg
     7081 attagctgca tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga
     7141 tcaataccaa aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg
     7201 attggattga tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa
     7261 acaccaaact cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga
     7321 acgataattt tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta
     7381 tataccagaa ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa
     7441 ggcattagct tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg
     7501 aatgacctca actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat
     7561 tgatgatgag tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat
     7621 aaaaccatca tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac
     7681 gctattaaaa aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa
     7741 cgagatttag cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg
     7801 cttgtagagg agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat
     7861 cgcgtacaag agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga
     7921 cgtaagccat cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata
     7981 aatcaattgc acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca
     8041 gataaggttc ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc
     8101 aaaaaaactg atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc
     8161 ggcaaaagtc aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta
     8221 gaggtcgcta aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt
     8281 aggccctttg aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa
     8341 aataattaat cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc
     8401 tttttttcaa cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac
     8461 tattatcctc atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta
     8521 ccactgttaa aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa
     8581 ccgaatgaat gctctttttg aattttatgc tgccttattg actgataaac agatgaacta
     8641 tatcgagctc tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt
     8701 cagccgccaa gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga
     8761 aatgaagctt catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct
     8821 tgcaaaatat cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga
     8881 caacagagat taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag
     8941 gacgttttta agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg
     9001 accaaggaga ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc
     9061 tttatcaagc gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca
     9121 acgcaacaaa tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc
     9181 gcggagcttg ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga
     9241 gctggtaaaa cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct
     9301 cgtccattga tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc
     9361 ttgggacagc aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat
     9421 attgttgcca atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat
     9481 acggcaggac ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca
     9541 ctagctaaac caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc
     9601 aacgttgcct atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt
     9661 gacggtgata ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc
     9721 aaatttaccg gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg
     9781 tcaagtcgta tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa
     9841 tatgatgaga aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt
     9901 aatgacttta tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta
     9961 aaaatgattc caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag
    10021 caaattgctc gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca
    10081 gagcttttaa caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt
    10141 gaagtcaaca aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg
    10201 tcaggtgata tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa
    10261 aacatgccaa atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg
    10321 caaggtggtt tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt
    10381 ggaggtggtc taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa
    10441 gctaataaga ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg
    10501 tattctgcct ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat
    10561 cttttttata aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc
    10621 actattagct gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc
    10681 aagtgataaa aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga
    10741 ctgaaattgg acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata
    10801 ttcgcccaag ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac
    10861 tgaggataaa actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg
    10921 ccatatgaaa tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag
    10981 tccttgaatt ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt
    11041 cgcttttttt gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc
    11101 tcgtaattct tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg
    11161 ccataagtcg tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc
    11221 ttttcagtta aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa
    11281 gctatcacgc cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac
    11341 gcttcaatat cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat
    11401 agcttggttg ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc
    11461 agagccttgg aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata
    11521 ggatcaaatt taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc
    11581 gtaaatgcca ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc
    11641 atcgtcatac caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct
    11701 ccctgaaaaa taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg
    11761 ctctgcaaga ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa
    11821 ataccgattt ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct
    11881 aaatatctga tcttgaaata gatctgcttc tacttaattt attcgaaaaa tagtttgaaa
    11941 aataattgct ttttttgatt ttcaattt
//
LOCUS       DARYUW010000058        11910 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYUW010000058 DARYUW010000000
VERSION     DARYUW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11910
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            1..284
                     /locus_tag="TVW11_001605"
                     /pseudo
     CDS             1..284
                     /locus_tag="TVW11_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            281..766
                     /locus_tag="TVW11_001606"
     CDS             281..766
                     /locus_tag="TVW11_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1365689.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            763..2234
                     /locus_tag="TVW11_001607"
                     /pseudo
     CDS             763..2234
                     /locus_tag="TVW11_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001899253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            2188..2544
                     /locus_tag="TVW11_001608"
     CDS             2188..2544
                     /locus_tag="TVW11_001608"
                     /inference="COORDINATES: protein motif:HMM:NF014581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEL1365690.1"
                     /translation="MERKKTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKE
                     LMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKKNLFDIESYMKR
                     KGKAKLNRETVITRMQ"
     gene            2708..3019
                     /locus_tag="TVW11_001609"
     CDS             2708..3019
                     /locus_tag="TVW11_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1365691.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            3023..3238
                     /locus_tag="TVW11_001610"
     CDS             3023..3238
                     /locus_tag="TVW11_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1365692.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            3258..4124
                     /locus_tag="TVW11_001611"
                     /pseudo
     CDS             3258..4124
                     /locus_tag="TVW11_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4144..4407
                     /locus_tag="TVW11_001612"
     CDS             4144..4407
                     /locus_tag="TVW11_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1365693.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            4411..4800
                     /locus_tag="TVW11_001613"
     CDS             4411..4800
                     /locus_tag="TVW11_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1365694.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            4712..7141
                     /locus_tag="TVW11_001614"
     CDS             4712..7141
                     /locus_tag="TVW11_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1365695.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            7145..9268
                     /locus_tag="TVW11_001615"
     CDS             7145..9268
                     /locus_tag="TVW11_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1365696.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            9281..9520
                     /locus_tag="TVW11_001616"
     CDS             9281..9520
                     /locus_tag="TVW11_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1365697.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            9495..11042
                     /locus_tag="TVW11_001617"
     CDS             9495..11042
                     /locus_tag="TVW11_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1365698.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            11138..>11910
                     /locus_tag="TVW11_001618"
     CDS             11138..>11910
                     /locus_tag="TVW11_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1365699.1"
                     /translation="MKLVIAEKPSVALSIAKVLGANKKKDGYYEGNGYKVSWCVGHLI
                     QMANPDVYDEKYAKWNMVDLPIIPKDYKYEVAKSTKKQFNILKKLMNDKEIDTVINAC
                     DAGREGESIFRLVYNQVNCKKKMKHLWISSMEDTAIKDGFDHLKDGKDYDNLFESAQA
                     RAIADWLVGMNISRLYSCLYKQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVELS
                     TNSFTLSTDRIDDEIAAEQLLTLVGNKIEITDVIQKEKIT"
BASE COUNT         4490 a         1757 c         2645 g         3018 t
ORIGIN      
        1 gctgcaaaag ggaggatttg attttgataa gaacgcatat attgaatccc ttgtaaatac
       61 ttccgttctt atcttggatg acttgggaat agaaagagat acaagctatg ccaaagagca
      121 ggtatataac attgtcaaca acaggtactt aaagcagaaa ccgactatct tcaccactaa
      181 cctttcctac gacacaatcc aaagaggatt ttagaaagat tattcaaaga gataaattga
      241 atcgaaataa agataggtta ctgaatggag gtgagagaac ttgatcaatg aagaaatagc
      301 aagaaaaacg ctgaatatgg aagtaagagc tgctaaagta acaggaaagt taattctgaa
      361 cttattaaag aaattgatga aagaagcaga aaaacttgga ggacttgaaa agctggttaa
      421 tgctaacgga aatgaagtaa agctaaaaga tatggtaaaa aagggacagc ttgaagaaat
      481 tcctgttgaa gaagcggagc ttaaggaact gaaaaaagaa cttaatcggt atggtgttaa
      541 gttttcagtg atgaaggata aggaaacagg aaaatactct gtattctttc aagccaaaga
      601 tatgaaagtg atggataaag cctttaagca cgcattagca cagtctgaaa agaaaacgga
      661 aaggaaagaa tctattcaca agaatattga gaagtttaag gaaatggcta agaactctgt
      721 ttccaaagat aaaatcaaga ataaacaaaa ggagcagagc ctatgataga taaaatatta
      781 aaggacatca aaggcttatt taaggtgcag gataagacaa agtttgtaaa gcaaaacatt
      841 ccctatcttg catttttcta tttaggaaac atctttgccc atcatgtgag aagctatacc
      901 ggtggtgatg tcatagataa aatctttcaa gggatattgg agatcaacac gatgagtttt
      961 cttccaagta ttcatccggc ggatatttta atgggcatag gaatggctgc tttaattaaa
     1021 tttattgtct ataccaaagg taaaatgcta aaaagtttag acaggggaaa gagtatggct
     1081 cagcaagatg gggaaataag aaagatattg agccatacat ggatgaaaag tttcaaaaca
     1141 atatcttgct tacccagaca gaacgcctaa ctatgaatgg tagaccggct aatccaaagt
     1201 atgctcgtaa caagaatgta cttgtaatcg gtggatcagg aagtggtaag acaagatttt
     1261 atgtaaaacc gaaccttatg cagatgcaca gtagctattg cgtaaccgat ccgaaaggaa
     1321 cgatagtcat tgaatgtggc aagatgcttg aagacaatgg atatgagata aaaattctaa
     1381 ataccataaa cttcaaaaag agcatgaaat acaatccctt tgcctatatc cattctgaga
     1441 aagatatact caaattagtg cagacaatca ttgcaaatac aaaaggtgag ggagaaaaag
     1501 cgggtgaaga tttttgggtc aaagcggaaa aactctacta cacagcactt atcggatata
     1561 tcttctatga agctccaaga gaagaaaaga actttgcaac gctccttgat atgatagacg
     1621 cttcagaagt aagagaagat gatgaaacct atatgaatcc aatagacaga ctctttgaag
     1681 cacttgagaa aaaggagcct acgcactttg cggtcaagca atataaaaaa tataaattgg
     1741 ctgcgggaaa gacagcaaaa tctattctta tatcttgtgg tgcaaggctt gctccatttg
     1801 atattcagga acttagagat ttgatgagtg aagacgaact tgagcttgat acattgggag
     1861 atagaaagac agcactcttt gttattatct ctgatacaga tgataccttt aactttgtag
     1921 tgtctattat gtattcacag ttatttaatc tactttgcga taaggcggat gatgtatatg
     1981 gtggcagact tcctgttcat gtaagatgct tacttgatga gtttgcaaat atcggcttaa
     2041 ttccaaagtt tgagaagctc atagccacaa ttagaagtag agaaatttca gcgagtatta
     2101 tcttacaggc acaatctcag ctaaaggcaa tatataagga taatgctgat accattgtgg
     2161 gtaactgtga tagtacctta ttcttaggtg gaaaggaaaa aaacactaaa agagctgtcc
     2221 gaaacgcttg gtaaagaaac tatcgacctt tacaacacat cggaaacaag gtcaaatcaa
     2281 aagagctttg gacttaacta tcaaaaaaca ggcaaagagc tgatgagtca ggatgagatt
     2341 acggtcatgg atggtggaaa atgtatcttt cagcttagag gtgtcagacc ttttctttca
     2401 gataagtacg atattacaaa gcacaagaac tataagctgc ttgaggacta tgataagaaa
     2461 aatttatttg atatagaaag ctacatgaaa cggaaaggaa aagcaaaact gaatagggaa
     2521 acagttatta caagaatgca gtaagtctac aaaatagatt tgctgctttt ttatgcaaaa
     2581 gtaaggaggc aagatgataa ggatcagaag tcccactgag taaaaaacta aatagtatga
     2641 gtatagcgat tggaaaagta atacttccgg tcgctttttt tattgaaatg aaaaggagaa
     2701 atttttaatg aagcaagaaa tgattaacat caacgccaac ttagtggcag aacctacttt
     2761 ctcaagtttt gaaaaagagg gtaaagaagt agaagttgta aattttacgc ttgtaaagaa
     2821 gtacggtaaa ggcaaggagt acatcaattg tgcagcctat ggagaaaaag cggataaagc
     2881 aaaggacttt gaaaagggcg atttgattca tgtattcggc tactttaaga agcgtgaaaa
     2941 agagggaaag acttacaaaa attttgtagt gaagtcatac aacaagattg aaaagaaaga
     3001 agaaaatgag gaggaataaa ttatggaatt tttcgcacag gcagtaaatg tattaaagat
     3061 tttggttatg gcagtaggag caggacttgg agcatggggt gtcattaacc tgatggaagg
     3121 ttatggtaac gataatccgg gagccaaaag tcaagggatc aagcaattga tggcgggagg
     3181 aggtattgtc cttatcggac ttaagctgat tccacttctt gcaaatgtac tcagataaga
     3241 agaaaaggag agcttagatg tttgggatat tcgacaaaat agaagaattc tttaaggagc
     3301 ttctactggg cggtatccaa gcaaacttag agtccatgtt tcttgacatc aacgacaagg
     3361 ttggtgcagt tgcaacagat gtaggaaaaa ctcctatggg gtggaatgga gatgtattta
     3421 cctttattaa aagcattaac gattcggtca ttattcccat agcgggacta attatcacag
     3481 cagtcctttg tatcgagctt atcaatatgg ttatacagaa aaataaccta catgataata
     3541 cggatacatt tgaatttttc aagtacatca tcaagatgtg aattgctgta tggttggtat
     3601 ctcacgcttt tgaattttca atggcggtct ttgatgtagc acagcatatg gtaaataagg
     3661 cggcaggggt gataaacacc tctgccaccg tttccggaga tcagatagtg gcgatgatgg
     3721 ataccctaaa agaaaaggga cttggagagc ttatcatgat tctctttgaa acctcgctca
     3781 ttaaagttgc catacaggca atttccatag tgattatgct tgtggtttac ggaaggatgt
     3841 ttgagattta tgtttattca tcggtttcag ccattccatt tgccacgatg ggaaacaaag
     3901 aatgggggca aattggcaca aattacatca aaggattatt tgcacttgga ctacaaggac
     3961 tctttttaat ggtttgtctt ggaatttacg cagtattagt taagacgatt gaaataacag
     4021 atatacacac aagtaccatg acgatacttg gttatgcggt tttgctgggg ttaatgatgc
     4081 taaagagcgg aacactggcc aaaagcgtat taaatgcaca ctaaaaaaga aaggaaagat
     4141 agtatgaata aaagaaaaac agtatttaca gcagtagtaa tggtcgcagg cattatggcg
     4201 gtaattgata gaatcaggct tcataacaaa gctgccgaat tagaagaaag aacacaggac
     4261 atcggtcgct gccataatga tttttgctta atgcagcaaa gatataacaa gaatacagat
     4321 gaacagcttg caattattca ggatgaaatc ggctctgtat atgaacactt tgaggagttt
     4381 tcaaagggta aagaagatgg gaggtaagct atggcgtatg taccaatacc caaggactta
     4441 aagaaggtca agacaaaggt agcctttaac cttacaaaaa gacagctcat aggatttacc
     4501 attgcaggac ttgttggaat acctgtctat ttatttatga gaaaggtagt accaaacgat
     4561 atagctttca tattccttat cgtgtccaca cttccaatct tttttatcac actttttgaa
     4621 aaggacggac tgacctttga gaaatatttt aagcatatct accttcataa gttttatcag
     4681 ccggcaaaga gagtgagaaa ggaggtttac cttgaacaag aaaagaaaaa ttcagcaact
     4741 aaagttagaa gaaaacaaaa aggcattaaa aaaggagaga aaggacttaa agcaaagtaa
     4801 gggaaagtct aacaaagaaa agagcggact acttgatctt atctttagaa aagagcaaaa
     4861 acgctatacg gtagaagata ccattcccta tcttagactc ttaaaaagcg ggatatgcca
     4921 gctcgatgaa aagcacttca gtaaaagcat agcctttcag gacattaact atcagcttgc
     4981 tttagatgaa gatagggatt tgatttttaa tcagtttgca aactttctaa attcctttga
     5041 tccaagcata gcgattgagt tttcctacat caatcagctt ggacgaaacg aagaaatgaa
     5101 atcggcaatt cagataccgg ataaagggga cggatttgac gatatacgac ttgagtttag
     5161 agagatgcta aaaagtcaga ttgtaaaagg aaataacgga ctgaaaaaat caaagtatgt
     5221 aacctttaca gtagaggcag acaatttaga acaggctaca tcaaaacttg aaagattgga
     5281 tatagatata ttatctaatc tcaaaagcat gggggtaaga gctgaaagtc ttacagtaga
     5341 ggaaaggcta aagattcttc acgatatatt aaatccgaat aagacctttg agttttccta
     5401 caaagacctg aagaaaaagg aaagtaccaa aacatatatc gtgcctgatg aatttaactt
     5461 tatgccaagc aggtatttca agtttgggaa gtttatcgga gcaacaagtc attttcaaat
     5521 ccttgcaagt gagctttcag accgtatgtt atcggagttt ttggatattg atgataacat
     5581 caatatatct tttcatatta aggcgattga ccagtcagaa gccatcaaga tggtaaaacg
     5641 aaaaaacacc gatattgata agatgcgaat tgaggaaaac aagaaagctg taaggtcagg
     5701 ctatgacatg gacattcttc caagtgattt aattacttac ggagaagatg taaaaagtct
     5761 tttaaaagat ttacagacaa gagatgagcg tatgtttgtt gtaagtattg tctttatgaa
     5821 ttttgcaagg acagtgcaaa agctcgataa caccatagct cagataagct ccattgcaaa
     5881 caagcataac tgtaaattga aaagacttga ccatacgcag gaacaaggct tagtgagcgt
     5941 gctgcctctt ggggtaaaca agattgaaat agatagaggg ctaacctcat catcaacagc
     6001 agtctttatg ccttttacaa cagaggagct ttttatcaat tcaagtaata gcctatacta
     6061 tggactaaac gctttaagcc ataacctgat tatggcggat cgaaagaaat taaagaaccc
     6121 aaacggtcta atcttaggaa ctccgggtag tggtaagtcc tttagtgcca aaagagagat
     6181 ggcaaatgcg attttagtaa cggacgatga tgtgattatc tgtgatccgg agggagagta
     6241 tggaaacctt gtaagacagt ttaatggaga agtcattaag gtcagcagta agtcaaaaga
     6301 ttacctgaat ccacttgata taaatatgaa ctacggtgat ggggacgcac ctcttaaaga
     6361 caaggcaaac ttcattatgt ctatgcttga gcttgtagtt ggtggtagtg gacttacagc
     6421 ggaagaaaag tccgttatag atagatgctt acctaagatt tacgaaaggt actttgaaaa
     6481 tccgacttat gacaatatgc ctatacttca agacctatac gatatgttaa aagggcagga
     6541 agaaaaggta gggaaaaagc tggcaacaga gatggaaatt tatgtttcag gttctcttaa
     6601 tgtctttaat cacaggtcaa atgtggactt aaataagaag ctactttgtt ttgatattaa
     6661 ggagcttgga agtcaattaa agaaaatagg tatgcttgtt atacaggatc aggtgtggaa
     6721 taaggtatcg caaaacagag gaaacaaggc tacaaggtac tatatagatg agtttcactt
     6781 gctgttaaaa gatgagcaga cagcttcata ttcggtagag atttggaagc gttttagaaa
     6841 atggggagga atcccgactg gtatcacgca aaatgtcaaa gacctactta tgagtaagga
     6901 aattgaaaat atctttgata atacggactt tgtcttaatg ttaaatcagg cttcgggaga
     6961 tagggaaata cttgcaagga aacttaaaat ctcacttccg cagcttagat atgttacgaa
     7021 ctccaatgag ggcgagggac tacttttctt tggaaatacc attgtgcctt tccttgataa
     7081 gtttccgaaa gatacaattc tttatcagaa gatgactacc aagcctgaag aagtgaggta
     7141 gcttatggat gggaagctga aaaaagattt tagagaaagg cataaggcaa gccttgaaag
     7201 ggagatgctt aaagctgaaa caagctctat acctgaagaa agtaagctaa agcataacga
     7261 tgattacaga ggaaaaattg tccatgacaa agatagattt caggacaagg ttcatgagaa
     7321 gataagcaag gtaagatctg aaaatgagca gatagagggg acttctaaaa gaaatgcaaa
     7381 gtatagggct tctgataagg gaagtgtaaa tgaagcagga aaggctgact atgatactga
     7441 ggtaaagaac gggaaaatct atgattcttt aggacaagac cttgataatg atggaatcat
     7501 agacagatac gataatgatt ttagggacag cgactacttt gaatcaacct atgatgtaga
     7561 ggataatcta cctcaaaaag aaaaatcatt agaaaatccc tctaaaaatc ataaggctca
     7621 aaagaataag tataaaagga aaaactattc cgaaagcctc tatacaagaa aaaaggacga
     7681 tgtaccaaaa gagaataagc ctgaagataa aaaggcaggg aaagatgttg cgggcgaaaa
     7741 agaacatagc agtctttcaa aagaccaaaa gaaaaagctg aagaaagata tggtaaaagt
     7801 atctgccctg tcaggacttg ccaaaggaag tgaaaccgta agagattacc tttctcatgg
     7861 aagtgatgaa aataaaggcg tagaagcggg agaaaaaaca gccgatgcaa gttcaaaact
     7921 cattcatggt ataaagagat actcagataa gaaaagagct aaaaaaggat atgagcttac
     7981 aaataaggac tataaaatca gaaagcgtaa atccaagtta gagtttcgtg atgccaaaga
     8041 ggaactgaaa aagacagatg agtataaaag agcaagtgcc tataaaagat ttcaaaagaa
     8101 aaatcaggta aaggcagcga tttctcgtga gaataagtca agactcagag atcggattaa
     8161 agagggactt atcggaacac tgaaaagctc aaaggatatg attatccgaa aagccaaagg
     8221 actaatgctt atcttcgtag gtatcatcat cttaggaaat tttgtgatta actttgcagg
     8281 aacaggcatg acaggcttta tgaactctac aaactctgtt cttacaacaa gctatttatc
     8341 aaagccaaat gttctaagtg aaatcaatca gaagttttct gctatggaga gtgagcttca
     8401 aagtgaagtg gatcatgtag aagagaatta tcccggatat gatgagtata tcttaaacaa
     8461 cacagagtat atcggtcata atgtccatga gcttttatcc tacattacat caaggtgcgg
     8521 agaggtaaag agtgtatcgg aagtagaaac catattaaaa gaattgtttg agtccatgta
     8581 tgaccttgaa tacagggaag aaattgaaat cagatacagg acagttacag aaacctatac
     8641 cgatgaagat ggcaatgaat ataccgaaag ccatgaagag ccttatgaat ataagaagct
     8701 cattgtaacg cttcataaaa aagagatgga cagcattatc cgaagggtct ttaaagacta
     8761 tcccgataat ttaaagcact atgaagcctt attccttgct caaggaaata tgggagaagc
     8821 ctttagaaat tctgacctta tcagtgctaa tggcggtgta ggtggtggga aagagtatga
     8881 ggcatcttcg gaagtacaaa agaagattgt taatgctgca tatatcactc catctccggg
     8941 tgcaggctgg tgtgccatgt gggtatcgca agtttaccaa aatgcgggac ttggatatat
     9001 cggaggaaat gctaatgata tgtatcgaaa ctataccttt acatccgata ggtcaaagct
     9061 caaggtagga atgcttgtag cggtagaaag cagcagtagc ggaagcacag caggacttac
     9121 ctatggtcat gtcggaatct atatcggaga cggcaaggtt attgataata tcggttatat
     9181 aagagtaact actttagatg attggattgc gactttttgt aaacaccatc cggtaggctt
     9241 tggttttcca ccaaatgtaa acagataagg agggaacaat atgaaaaaag aactgacagc
     9301 agtaaaaaac agaataaaaa agttaaagga taaaaaggct ctgattgatg aagaattgga
     9361 gcctttattt attcgtgaag aagaacttga aaatgaagaa atcatcatga tttgcagaaa
     9421 gaacaacatc acaatttctg atttaatgac aaaggtaaac agagaaaaag cagaactgaa
     9481 aaaggagagg acaaatgaaa accagtttga aaaagaataa taagttttgg acagcagcac
     9541 ttgcagtaat tgtaagtatt agctgcattt taggactttg gacggttgtt tacgccaagg
     9601 agaaaagctc tgacgctcct acaaaaaacg aagctgtcca aacggaagtt gaagtaaatg
     9661 taaagtatat ctttgaagat gaaaaggtat ttaaggaaga aaagattaag gcagagaaag
     9721 gacagcttct tgatagtggc gatcttccaa tgctccctga tgatatgaaa tttattgatg
     9781 aattcctgtt ttatgaagta aagggagatg gaaatgatga aattatccgt aaggtagcaa
     9841 agactgaggt taaggataag gaaacgcaaa cggaagaaga aaaaccaaag caggacgaaa
     9901 gcacgcaaac agaagctaca aaaacggagg ataaaggcac acagacagag ctttctaaag
     9961 acgatatttc taagatggaa aaagaggcta aagagcttca agaaaaattt gataagttaa
    10021 atggtgagct taaagacaag gataagcaga aagaaaaaat caaagacctt gaagatgaaa
    10081 ttgacagcct gaaagagaaa atgaagaaag ataaaggaaa taaggactta tcagaagata
    10141 tgaaaaagga aatagataag ctgactgata aggtgaaaga gcttgagaaa aaggcaactg
    10201 aaacaaagaa atcttctgaa gcaataaatt ctgttacacc gattagtcct atttccggaa
    10261 ttaagacaag ctcaagcatt tctccccaaa caccacagac ttctgtaagt agttccggta
    10321 aaggctcatc tgatacggtg agttcaggga atgctacaaa ggatacaagc aaaacagaag
    10381 taaaggagaa agaaaaggaa gttcgctatt ctaataaatt gacagcaaaa gcacctgcta
    10441 ataacagcag tcaagattcg tcaatggagg gggcaagtag taatgtaaat accaataagg
    10501 gagtagcttc atctccgtca aaggcaagag gaactgttac agaaaataaa gataatggaa
    10561 ataaagatta tccgattcat catggggata gcagcgataa taaagaaacg gatcaatatt
    10621 ccgctgatgc aagacagttt attacctttc aaactaaaaa cggtaagacc tttcatctca
    10681 tcatcaacca cgatgaggat agtgagaatg tcatgcttct tacagaagta tccgaagatg
    10741 atttgcttaa catggtagag aaaaaagaag ctccaaagca ggagattgta aaagaagaac
    10801 ctgttaagga agaagtaaag cctgagaaaa aagaagaaaa gagtaattta ggaacatata
    10861 ttattctgct tcttgttgta ggcggagcat tgggagcagg atactacttt aaggttgtaa
    10921 aaaagaaaga agataaggag cttgaagcat tagaggaaga agatgatgat ttcttttctg
    10981 aagctgaaag cgaggaagaa acaaatgatg tagatgaagt agaagcggaa gatgagcagt
    11041 aatgctgcac caaaaaaata cagtatttgg tgcaaatgca gggcgggaga ataaaatctt
    11101 tcgccctttt atattgaaaa caggaggcag tacagaaatg aagttagtca ttgcagaaaa
    11161 accaagtgta gcattaagta ttgcaaaagt acttggagca aataaaaaga aagacggata
    11221 ttatgaggga aatggataca aagtatcttg gtgtgttgga cacttaattc aaatggcaaa
    11281 tccggatgtt tatgatgaaa agtatgccaa gtggaatatg gttgatttac cgattatccc
    11341 caaggactat aagtatgaag tggcaaagtc aaccaagaaa caatttaaca tccttaaaaa
    11401 gttgatgaac gacaaagaaa ttgatacggt tatcaatgcg tgcgatgcag gtagagaagg
    11461 ggagagcatt tttagacttg tatataatca agtgaattgt aaaaagaaga tgaaacacct
    11521 ttggatttca tctatggaag atactgccat taaagatggc tttgatcatc taaaagacgg
    11581 aaaagattac gataatctct ttgagtcggc acaggcaaga gctatcgctg actggcttgt
    11641 cggaatgaat atcagcaggc tctattcttg tctgtataag caaaattaca gtgttggcag
    11701 agtacaaaca ccgactcttg ctatgatcgt aaaaagagat gatgagatag caaactttaa
    11761 gaaagaaaaa tattatacgg tagagctttc tacaaatagc tttacacttt caacagatag
    11821 aattgatgat gaaatagcag cagagcagct cttaacttta gtgggcaata agattgaaat
    11881 aactgatgtc attcaaaaag aaaagattac
//
LOCUS       DARYUW010000059        11354 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYUW010000059 DARYUW010000000
VERSION     DARYUW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11354
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(72..2753)
                     /locus_tag="TVW11_001619"
     CDS             complement(72..2753)
                     /locus_tag="TVW11_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1365700.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TVW11_001620"
     CDS             complement(3101..3487)
                     /locus_tag="TVW11_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1365701.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TVW11_001621"
     CDS             3568..4869
                     /locus_tag="TVW11_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1365702.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TVW11_001622"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TVW11_001622"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1365703.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TVW11_001623"
     CDS             5903..7117
                     /locus_tag="TVW11_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1365704.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TVW11_001624"
     CDS             7117..8352
                     /locus_tag="TVW11_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1365705.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TVW11_001625"
     CDS             complement(8561..9319)
                     /locus_tag="TVW11_001625"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1365706.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVW11_001626"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVW11_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1365707.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3405 a         2580 c         2261 g         3108 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttat
//
LOCUS       DARYUW010000060        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYUW010000060 DARYUW010000000
VERSION     DARYUW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(32..1213)
                     /locus_tag="TVW11_001627"
     CDS             complement(32..1213)
                     /locus_tag="TVW11_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1365708.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TVW11_001628"
     CDS             complement(1297..2532)
                     /locus_tag="TVW11_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1365709.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TVW11_001629"
     CDS             complement(2854..4092)
                     /locus_tag="TVW11_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1365710.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TVW11_001630"
     CDS             4400..6376
                     /locus_tag="TVW11_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1365711.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TVW11_001631"
     CDS             6440..7939
                     /locus_tag="TVW11_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365712.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TVW11_001632"
     CDS             7939..8865
                     /locus_tag="TVW11_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365713.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TVW11_001633"
     CDS             8874..9944
                     /locus_tag="TVW11_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365714.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TVW11_001634"
     CDS             9937..10860
                     /locus_tag="TVW11_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365715.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3259 a         2145 c         2282 g         3310 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagcat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacc
//
LOCUS       DARYUW010000061        10918 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYUW010000061 DARYUW010000000
VERSION     DARYUW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10918
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            6..596
                     /locus_tag="TVW11_001635"
     CDS             6..596
                     /locus_tag="TVW11_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1365716.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TVW11_001636"
     CDS             606..2168
                     /locus_tag="TVW11_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365717.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHQID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TVW11_001637"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TVW11_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1365718.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TVW11_001638"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TVW11_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1365719.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TVW11_001639"
     CDS             4388..5317
                     /locus_tag="TVW11_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365720.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TVW11_001640"
     CDS             complement(5707..6348)
                     /locus_tag="TVW11_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1365721.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TVW11_001641"
     CDS             6685..9156
                     /locus_tag="TVW11_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1365722.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..10496)
                     /locus_tag="TVW11_001642"
     CDS             complement(9330..10496)
                     /locus_tag="TVW11_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1365723.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT         3092 a         2114 c         2387 g         3325 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat cagattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatcg
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatattcc agtactgatc aactgtcaaa tttttgttat aagcaaaatc attgttttct
    10321 attttttgct caatttcagt aagtgcagct ctggcttcct gtagcgtttt taagttgctt
    10381 tttgtagcct ctttcttttt accttttaag taataacccc tacggacgta gtagcgttta
    10441 cctttctttg tatcgtaggt aaagatattt gggtattttg ttttgttgta tttcatttta
    10501 aaatcctttc atgtattttg acttttggac gaggtcgttt gaaaggatat tggcatcacc
    10561 tcctttgtgt gatataatta ggtataataa aacgcccttt ttaatggttg ttttatattt
    10621 tgtgtagtct ccacgttgcg ctttggtcgg ttgtaacgtg gggctttttt gttttattta
    10681 ctaaatttta aatatgctgg tattgataaa actaatgtaa aaaacaaccc aactaagaac
    10741 tctaagaatt tacccttaag caaaaaactt atagctacta agcagaataa gataccaatt
    10801 aaaaacatta ttgctgcaat tgcatctgta aatgtaatat ttttagattt gctttttgat
    10861 gtattcgaca aaatacagag tgcaatatca cagttaatat ttaattgatg ttcgatga
//
LOCUS       DARYUW010000062        10828 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYUW010000062 DARYUW010000000
VERSION     DARYUW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10828
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..149
                     /locus_tag="TVW11_001643"
     CDS             <1..149
                     /locus_tag="TVW11_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1365724.1"
                     /translation="AWGVINLLEGYGSDNPGAKSQGIKQLMSGGGIVLIGLKLIPLLA
                     NVLR"
     gene            149..1012
                     /locus_tag="TVW11_001644"
     CDS             149..1012
                     /locus_tag="TVW11_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365725.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1085..1579
                     /locus_tag="TVW11_001645"
     CDS             1085..1579
                     /locus_tag="TVW11_001645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1365726.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1583..1993
                     /locus_tag="TVW11_001646"
     CDS             1583..1993
                     /locus_tag="TVW11_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1365727.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            1953..4430
                     /locus_tag="TVW11_001647"
     CDS             1953..4430
                     /locus_tag="TVW11_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1365728.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            4432..5457
                     /locus_tag="TVW11_001648"
     CDS             4432..5457
                     /locus_tag="TVW11_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1365729.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            5423..7711
                     /locus_tag="TVW11_001649"
     CDS             5423..7711
                     /locus_tag="TVW11_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1365730.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            7724..8011
                     /locus_tag="TVW11_001650"
     CDS             7724..8011
                     /locus_tag="TVW11_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1365731.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            8016..9452
                     /locus_tag="TVW11_001651"
     CDS             8016..9452
                     /locus_tag="TVW11_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1365732.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            9705..10298
                     /locus_tag="TVW11_001652"
     CDS             9705..10298
                     /locus_tag="TVW11_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1365733.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            10291..>10828
                     /locus_tag="TVW11_001653"
     CDS             10291..>10828
                     /locus_tag="TVW11_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1365734.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIY"
BASE COUNT         4314 a         1389 c         2236 g         2889 t
ORIGIN      
        1 gtgcatgggg agttatcaac ttacttgaag gatacggatc agataatccc ggtgccaagt
       61 cgcaaggaat caagcaattg atgagcggtg gaggaattgt tttaataggg ctgaaactaa
      121 ttccgctact tgctaatgtc ttgagataat gtttgattta tttggaaaga tagaagagtt
      181 tttcaaggat attatgattg atattattaa agataatctt tctgcaatgc ttgtggatat
      241 taatgataaa gtaggaaccg ttgcaggaga agtgggaaag actccgagtt cttggaactc
      301 ggaggtcttc accttcatta aatcaatcaa taccaatgtt gttttaccca tagcagcgat
      361 aattctaacc gcaatacttt gcatagaact gattcaggtg gtaatgagaa aaaattctat
      421 gcacgatacg gatacctttg aattttttaa gtacattatt aaaatgtgga tagctgtatg
      481 gcttgtgtct catgcgtttg atttttcaat ggcagtcttt gatgtggcac agtccatgat
      541 aggaaaggca gcaggtgttg tggggacaag tgcgaatatc acaccgggaa attttgatgc
      601 tatggtagaa gcccttaaaa caaaggaact tggaacactc attgggattg cactggagac
      661 gggattagtt aaattttctt taacgattct atcaatctta atcactgtaa tcctatatgg
      721 aagaatgatt gagatatata tctattgctc tgttgcggca attccatttt ctacgatggg
      781 aaataaagaa tggtcaaata tcggaacaaa ctatataaaa agtctatttg cccttggact
      841 tcagggactt ttcatcctaa tattttttgg aatttacgca gtcttagtca aaaccgtaaa
      901 ctttacggat atccacacaa gtattttaca ggtattggca tatggattga ttcttggagt
      961 aatgatgatg aaatccggaa gtatagcaaa ggcgatttta aacagtcact aaaggacttt
     1021 agttcaaaat gagcaaaagt tgatgaaata atcagaacaa aaaatataat tattggaggt
     1081 aagaatgaat aaaataaata aaaaaacaag gattttgata ggagcaggct cagccctttc
     1141 tatcgggaca attattacag tgctattaaa aaagaaaacg aaaaaattat ccgatcttga
     1201 agaagatgat tttgactttg attttgatga aatagaagaa gattcttgtg tcaacgataa
     1261 atttgctaca gaaaatgata aagatgatac agtaaaagga gaaatagatt ttttagtaga
     1321 tgaatcaaag acggagaacg aaaagcaaga agagtttaga gatttatcgg taaaggtaat
     1381 ggatcttctt ctaaaagaag taatttcaat gagtgaaacc ttaaatttgg taaaaagaga
     1441 tattgataga ataggtgaag taaaagcatt ggttgaagaa ctggaaaact gtaaagaaga
     1501 aattatctca ctttgggagc acatggaaaa gttatccgat ttaagagaag aaattaccgg
     1561 caaaaagaat agaggttagg ctatggctta tgtaaagata ccaaaagacc ttacaaaagt
     1621 aaaaaccaag gtagccctga atatgacaaa aaggcagctt ataggtttta gcatagcagg
     1681 gcttatcggt tttcctgtat atatgctgtg taaaaatttt cttagtacag atatttccat
     1741 gattataatg agtatagtag ttctacctgt tctttttgta acgctttatg aaaaggacaa
     1801 tttacctttt gaaaaacatt tagcatatat cctcaggttt cataaaagta aaaagatcag
     1861 gctatataaa gcgaggagca tttatcatac agagagagca aaaaagcaag atataggaaa
     1921 taaaaataag gcaagcggaa ggaggaaaaa agttgaacaa agacaaaaga aaaaaacagg
     1981 aacaacgaat taaaaaggat gagttggagc ttaggaaaaa tagaaaggag ctatccgaac
     2041 ttaaaaaaac aggaaagaaa aaaacaaagt ctaaaacaaa agggaaatca tcgaagaaga
     2101 atgggtggtt tccttttttt atgaaagagg agaaaaaaga aaccgtacag gataccattc
     2161 catataagcg aatgttaaaa gacgggattt gtcaaattga aaagaataag tttaataaaa
     2221 ccattcgatt tttggacatt aactatcgct taatggaaga aatagaccaa gagggaatat
     2281 tttcggaatt ttcttctttt ctaaatttct ttgactcatc tgtggaagtg gagttcagct
     2341 atatcaacag tatcggagaa aatgaagaaa tcaataaact gattgatatt aaggaaaata
     2401 tagatgattt taatgaaatt agaaacgaat atagacaaat gctcttaaat caaagcagca
     2461 aagggaataa tggattatca aagagtatgt acattacctt taccatagag gcggaggact
     2521 taaagcaggc aaaaagtaga ttagagcgaa tggaaatgga tgtattaaac aactttaagc
     2581 agatgggagt gaaagcctat gtgttagatg gagaggaaag acttaaaaca attcatgaca
     2641 ttttaaatcc aaatgataaa cttgtttttt cctttgagga tttgaaatac agcggactga
     2701 cgactaagga atacattgta cctccgtctt ttaacttttc caagccgacg tattttaaga
     2761 caggagaagt ctttgcggaa gtaaattttt tacagctttt agcatcagat attaaagatg
     2821 agatgttatc agagtttttg gcattggaag aaaatatgat tgttactttt catatcagag
     2881 caatcgacca gatggaagct attaaacatg taaaaagaaa aataacggat ttggataaga
     2941 tgaagcttga ggaaaacaaa aaagctattc gtgcgggata tgatatggat atcttgccaa
     3001 gcgaccttgt aacttatggt gcagaggcaa agaacttgct atcagaacta caaaaccatg
     3061 atgaaaagat gtttctcata acaattttat ttatgaacac gagtaaaagt aaggggaaac
     3121 tcgataatac ggtatttacc ttaaagtcca ttgcaaatag acataattgt agtttgaaaa
     3181 acctaaatta tagacaagaa caagggcttg ttgcaagcct tccacttggg ataaatgaag
     3241 tggagataga acgaggactt accacaagtg cagcagctat ttttatacca tttacaacag
     3301 aagaactctt tatcaaggga gaaagcctat attacggact aaatgcacta agcagaaata
     3361 ttattatggc ggacaggaag aaattaaaga acccaaatgg tctaatctta gggacaccgg
     3421 gttctggaaa gtcctttgca gccaaaagag agattactaa tgcgtttttg attacagatg
     3481 atgatattat cattgcagat ccggaagcgg aatattctcc gcttgtagag gcactaaaag
     3541 gacaagttat cagaatttct ccgatttcaa aagactatgt caatccactg gacatcaata
     3601 ttgactatgc ggatgaagat aatcctttgt ctttaaaatc cgactttatt ttgtccctat
     3661 ttgaattggt ggttggagaa aagaaattaa gtgcagaaga aatttctgtt atagaccgtt
     3721 gtttaccaat tttatataaa acctactttg aaaatcctgt gccggaaaat atgccaattt
     3781 tagaggattt atataatctt cttcaaaaac aggaagaaat agtaggaaaa aagcttgcag
     3841 tagaaatgga gatctatgta aaaggaagtc ttaatgtatt taatcataga acgaatgtag
     3901 atacaaataa cagagtggtt tgctatgaca tcaaagaact gggaaaacag cttaaaaaga
     3961 taggaatgtt agttgtgcag gatcaagttt ggaatagagt tacaattaac agagcaagta
     4021 aaaaagcaac cagatattat gttgatgaat ttcatctttt gttgaaagaa ccgcaaacag
     4081 ccaattattc gattgaaatc tggaagcgtt tcagaaaatg gggtggtatg ccaacaggac
     4141 ttactcaaaa tatcaaagac cttcttgcaa gcccggagat tgaaaatatt tttgataata
     4201 cggattttat tttaatgctt aatcaagcag gaacagatag ggatatttta gccaagaagc
     4261 tcaatatctc caagcatcag ctttcttatg taacaaattc gggggaagga gaaggactta
     4321 tcttttatgg aaatacgatt gttcctttta tcgatcagtt tccaaaaaat acaaaactat
     4381 attcactaat cacaaccaaa cctgaagaag taaaaaaggc aggtgaatag gatgagtgtg
     4441 agcagaagta aagaggaatt catcaaagaa aatacaaata aaattatttg ttcggatgca
     4501 cttgaaactt taagaaaaat tccagacgaa agtataagct gctgcattac atctccccca
     4561 tactacaggc tcagaaacta tcataaagaa ggtcagatag gaagagaatc tacagtagaa
     4621 gaatacttgg atagattgtt acaggtattt cgtgaagtaa gaagagcttt aaaaaaagaa
     4681 ggtacttgct ttatcgtaat tggagattct tatgctgatt caggaggtgg aaagggacaa
     4741 tacattgatc ctaaatatcc aaaggcaaga aatggaagta acgctttagc tacagaaaat
     4801 atctcagggt acaagtcaaa agatttaatg ggaatacctt ggagattagc gttacttcta
     4861 agagaggatg gttggtatct gcgttctgat attatctggc ataaggaaaa tgctatgccg
     4921 gaggcgtgta gagatagacc tactcgttcc tatgaacata tttttttact tacgaaatca
     4981 ccaaaatact attatgacta tgatgctatg gtagagccga tgaaagaagt cagtaaaaaa
     5041 agatatgtaa gaggaagaaa atcggataat aaatatctga aagaaaattc cggagcaaag
     5101 ttgcaaaaaa tcaatgaagc aagaaaatat ggagaatata agggcgataa tgtcccgcag
     5161 tttcgtaata aaagagatat ttggactatc aataccacat cttttagagg caatcattat
     5221 gcaacatttc caccgaaact tgttgagatt tgtatgattg caggttgtcc taaaaatgaa
     5281 attgtacttg atcctttcat tggaagtgga acggtcggat ttgtggcact tcgtcataac
     5341 agaaagtaca ttggaattga attaaatgag gagtatgtaa atcttgcaaa gaatagaatc
     5401 agtgaggagg tgaaaaaatt taatgaagaa caaaaacaag aggtacaaaa agaatagaga
     5461 aaaactctta aatcaagaaa tacagtcttt acaatctcaa actcaagata attatgaaac
     5521 aggatcctca aaaaatcaga atgaaacctt gctgaaagac gaaacttacg ataagaaaca
     5581 atttttatct gaaaagaagt tatccaatca tttggataat agacatataa ataattattc
     5641 ggatagaact atatcttctt attgcttgtc ggatacggga aatataaatc aaaataggtc
     5701 ttcctttcaa gctgaaaaac ataaaaaaaa gatgcaaaag cagataaata aatttcaaaa
     5761 gggagaaaag gaagtctacg atcctttatc aaaagatatg gataatgatg gtgtaataga
     5821 caggtatgat gtggatttta gggatagcaa agtatcatat cgaactctta cagatgatga
     5881 aaagtatgat aataaccaaa atgataaagg aaaaaattat aatgactatg taaaaaatcc
     5941 aaaatctaag aataagaggt ataaaaatta tgtaaaagac acattttcta aggaaagaat
     6001 gaaatcagaa aaccagaaga aatatgtgag gagcaacttt gatgatgaag agttcacaag
     6061 aaataaggat acgaaaaata atttatttca ggacgtaaat aataaaagaa aaactaccga
     6121 taaaaattca tcacgaaaaa gaaaaggaaa atttgaaaat aaggaaaaga aaatatccaa
     6181 gttacagcag aaaaagcaaa gacaagagca aaaactgaaa aataagggaa ttgacgggaa
     6241 aagtcaaagt gctaaaagtg cagtaatagc aacgggtatg gcaaagaggt atttggaaag
     6301 tggaaaagag gacaatgccg gagtaggtac tgcttataag gttacagatc aggtcgaaaa
     6361 tatttcaagg aaaatatatt atcatggaaa aaagaaaaat ttaaaaaggc aaaaaaagat
     6421 aacaaaatta ggtaaaagca ttgataaaca ggagaagaaa ctcttttttc aaaagaatat
     6481 ggaagagatg aaaaaaagcg tggattacca aaatacctca aggctcagac aattctttaa
     6541 gagaaggcaa tataaaaatc agattcaaaa gaagtataaa gatagtgtga aaaacagaat
     6601 aaaaaaatcc tttatagagg gcagtaaaag atttggcgaa tttgtaaagg gcagagggaa
     6661 aaagataata tttctatcac ttttagcggt aggaatattt tttatgttat ttcaggctgg
     6721 gagcatgatg atgaatatgg gaacgggaat ggtaagtaat actgtttcaa ccacctactt
     6781 atcatcagaa gacaccttaa aagaaatcaa tcagaggttt tcatctttgg aacaggcttt
     6841 gcaagaagaa atggacagtg tggaggaaaa tcatccgggc tatgatgaat atattatcaa
     6901 aggaaaagag aaaattggtc ataatgttca tgaactcttg tcatatatca cagcccgtta
     6961 tggaattgta aagaatattt ctgaagtaga aagtgaacta aaacatctgt ttcaaaaaat
     7021 gtatacgctg acttataaag aagagattga aatcagatat agaactgtta catccagcta
     7081 tacggatgct gatggcaatg aacatactga aagtcatgaa gagccgtatg agtataggaa
     7141 actcattgta accttagaaa aaagagagat ggacggaatt attagagaag catttaagcg
     7201 ttatcctaat aatttggcac actatgaaac tttatttttg acacaaggaa atatgggaga
     7261 agtatttgga aatattgacc ttataaattc aaatggtgga attggtggtg gtaaagagta
     7321 tgaagcatca agtgaagtgc aaaagaaaat agtgaatgcc gcttatatta caccatctcc
     7381 aggagcaggt tggtgtgcca tgtgggtatc acaggtctat caaaatgcag gacttggatt
     7441 tattggagga aatgcttgtg atatgtatcg aaattatact tttacttctg ataggtcaaa
     7501 gttaaaggtt ggaatgcttg ttgcagttga aagtagcagt agtggtagca gtttaggtgt
     7561 tacctatggt catgtaggta tttatatcgg agatggaaaa gtaatggata atatcggaca
     7621 cataagagta actaccctag atgattggat tgcaacattt tgcaaacatc accctgtagg
     7681 ttttggattt ccaccatcag tacaaaaata aggagggaat attttgaata aaaaatatag
     7741 aaaaaatata gaaaagcaaa aagatattca gaaaaaaata gaagaactcc agttaaaaca
     7801 ggagatgtta aaagaagaac aggaagagat ggaaaatatt gaggttttaa aggaataccg
     7861 aagtattgac atttctattg acgatttttt agaaatgatg agacgttata aaaaagagga
     7921 aaaacaagaa aaaatgaagt tacaggaaat gagaaataca gaaaatcata ataatatgga
     7981 ggaaaatcat gaaaatcaaa tggaagaata aaaaaatggc gataacattg tccggagtaa
     8041 tctttttgat acttgcttta cttggaacaa tgcttttcaa tcaccagatt gtttttgcac
     8101 aaggtagttt aatcccgaca ctgattagtc ccacagaagt tttagctcaa actaaagtgg
     8161 aggttaagat aaaatatata tttaaggatg agagtgtata taaggaagaa ataattgaag
     8221 tagaaaccgg gcaagttctt gacagtgggg acctaccaat gttagaggat aatatgaaat
     8281 ttattgacga atttttgttc tataaagtaa agggagacgg tacagatgag attatccgta
     8341 aagtagaaaa aattacagtt aaggataaag aaattcagac agaagaggaa aagccaaaac
     8401 aggacgaaag cactgagacg gaagataaaa aaacagaaga taagggaaca cagacagagc
     8461 tttctaaaga tgatatttcc aaaatggaaa aagaggcaaa agagcttcag gataaacttg
     8521 ataaattaaa tggtgaaatc agggataaag acaaactaag cgataaacag aaagaaaaaa
     8581 tcaaagacct tgaagctgag attgaaagtc tgaaagaaaa aatgaagaaa gataagggaa
     8641 ataaagactt atcagaagat atgaaaaagg aaatagataa gctgacggaa aaggtgaaag
     8701 agcttgagaa aaagccaact gaaacaaaca aagctcctgt aacatcacag tctgttacac
     8761 cgattagtcc tatttcaggg attaagacaa gctcaggtat ttcttctcaa acaccacaga
     8821 gttccggtaa aggttcatct gatgcagtaa gctccggcaa tactacaaaa gatacaggta
     8881 aaactgaatc aaaggagaaa gaaaaggaag ttcgctatcc caataagctg acaccgaaag
     8941 ctcctgctaa taacagtagt caggattcat caatggacgg tgcaagtagc aatgtaaata
     9001 ccaataaggg tgtggcttca gctccgtcaa aggcaagagg aactgttaca gaaaataaag
     9061 ataatgcgaa taatgattat ccaattcatc atggggatag cagcgataac aaagaagcag
     9121 ataagtattc agcagatgca agacaattta ttactttcca gacaaaatcc ggaaagacat
     9181 ttcatttaat catcaatcac gatgagcaaa gtgaaaatgt aatgcttttg actgaagtat
     9241 ctgaagatga tcttctgaat atggtagaga agaaggaaaa cccgcaagaa gaaatcaaaa
     9301 aaatggaaga aacggtaccg gaaagcgaag taaaaaaaga agagccgaaa aaggaagaag
     9361 gtaaaggtag cggctcatat atttttttag gaatcatcgt tcttgcagta gttggagcag
     9421 gatattactt taaaatctac aagaaaaagt aggaagatga tgattatgat gaagatgagg
     9481 aagaatatga tgaatttgaa gatgagtatg aaaaagagga cgatacagaa gatttggaag
     9541 aaacagtaga agaacagcat aacatagatg atatggcaat cgactcttat gatgaagaag
     9601 atgaggaata aagttataaa aagagaaatg taaaccctga tgttgcgttt acacttaaaa
     9661 aatggtataa tgcaagtgta aacgcaacaa agggggtgga tgggatgaat tatgaaaata
     9721 aaattgaaaa atatttgaag caatcaggtg gaattattac aacagcatac tgtaaggaaa
     9781 ataatatacc gacgatatat ctcagtcgac tattgaaaga tgggagattg tcaaaagtaa
     9841 gaaaaggaat ttatataacg aaagatgggg attacgatga gtattatttc tttcaacatc
     9901 agtataaaaa ggcgatattt tcttatgaaa cagcacttta cctgcttgga caaacagata
     9961 aaattccttg gagtatcgat gtaaccgttt ataacggata taaatttaat gaaaaaccga
    10021 acggtttcaa tgttcattat gtaaaaaaat caatttatga cttaggggta acccaaaaac
    10081 ctacaatgtt tggaaataaa gttaaggtat attcatatga gaggacactc tgtgatttta
    10141 ttgctcataa agaagaaatg gatatagagg tttatgtaaa acttattcaa tcatattcct
    10201 cttataaaga aagagatatc cattccctct atgacattgc aatgaaaatg ggaattgaaa
    10261 ataaagtaag agaggttatg gaggtggctt atgaataaag ctaaattaac ggctctttgc
    10321 cataaagtta gtaaagaagt cggtctttcg tttaatgctg ttatgttata ttatttttta
    10381 gaaagtattt taaaaaaatt agcaggaagc aaatatagtg aacgatttat ttttaagggc
    10441 ggctttttgt tatcaagtgt agttggaatt gattcaagaa gtactgtaga tatagacttt
    10501 cttttgagaa atatgcaact atcagaagaa aatattgttc aaatgctgaa cgaaacttta
    10561 aaaccggaag aattcgacga tattttttat gaattgcaaa acattgtgcc aatcaaagaa
    10621 gaagatcaat atggaggatt tcgtgcaaat atcttatgta aaatggaaaa tataagacag
    10681 attgtaccac ttgacattgc aacaggagat gttattacac ctcatccgat agattataag
    10741 tatgtgagtt cttttggaga agaagaaata ataatcaagg cttatccgat agaaactatg
    10801 cttgcagaaa aaatacaaac tatttatg
//
LOCUS       DARYUW010000063        10617 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYUW010000063 DARYUW010000000
VERSION     DARYUW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10617
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TVW11_001654"
     CDS             complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TVW11_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1365735.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1772..2485)
                     /locus_tag="TVW11_001655"
     CDS             complement(1772..2485)
                     /locus_tag="TVW11_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1365736.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2506..3153)
                     /locus_tag="TVW11_001656"
     CDS             complement(2506..3153)
                     /locus_tag="TVW11_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1365737.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TVW11_001657"
     CDS             complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TVW11_001657"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1365738.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TVW11_001658"
     CDS             complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TVW11_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1365739.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6592..7374)
                     /locus_tag="TVW11_001659"
     CDS             complement(6592..7374)
                     /locus_tag="TVW11_001659"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1365740.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TVW11_001660"
     CDS             complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TVW11_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1365741.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8802..9434)
                     /locus_tag="TVW11_001661"
                     /pseudo
     CDS             complement(8802..9434)
                     /locus_tag="TVW11_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9436..10203)
                     /locus_tag="TVW11_001662"
     CDS             complement(9436..10203)
                     /locus_tag="TVW11_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1365742.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10485..10617)
                     /locus_tag="TVW11_001663"
                     /pseudo
     CDS             complement(10485..10617)
                     /locus_tag="TVW11_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3131 a         2398 c         1946 g         3142 t
ORIGIN      
        1 gtcctctcca gatgttagct tgtcaactac ccactacagt tgacatggag cctgattata
       61 ccgttaaata agctgccaga tcagctaagg cacgtttagc gatagcttca tagcgttcct
      121 ttttatctct gatacgaggt ccgtcaagct ctttaataat accaaaattg acattcattg
      181 gttgaaaatg cttgctgtcc gcgtgtgtaa tataataagg caggctgcca attgctgttg
      241 tatttggaaa aacaagtggc tcttcttcct tgaatagccg agcagcatta atgccagcca
      301 caagtccaga agctgctgac tcgacatagc cctccacacc ggtcatctga cctgcaaaga
      361 aaagcctgtg attagcgcgt gattggaagc cttgtgtcag aagctttggt gaatccatat
      421 aggaattacg gtgcatcaca ccgtaacgca caaactcagc atgctcaagg cctggaatca
      481 tttggaaaac ccgcttttgc tctccccatt ttaaatgtgt ctgaaagccc acgatattat
      541 aaaggctgcc tgcagcatta tcctgacgca gctgcacaac agcatagggc gtcttgaaat
      601 caccgtcacg tggtcccttg taatcatctg gatattccaa gccaaccggc ttcattggac
      661 cataaagcat agtcttaatc ccacgctttg ccataacctc aattggcata cagccttcaa
      721 aatacttttc cttttcaaaa gcatttaaag gagcttcctc tgctgttgtc aaagcctcgt
      781 gaaaggccat aaactcttcc ttggtcattg gacagttcag ataagcagct tctcccttat
      841 catatcgcga ttttaaataa accctatcca tgttaatggt tgacttatcg acaattggag
      901 ctgctgcgtc gtaaaaataa aagccagcac caccatttaa ggcatgtatt ttttcagcaa
      961 ggctgtcact ggtcaagggg ccagttgcaa ttactgtaat agcatcgcta ggaatgtcaa
     1021 taacctcctc acgaatgatt tcaatcagag ggtgattttc aagctcagct gtaacagcct
     1081 tggcatagcc ttcgcgatct acagccattg ctcctccggc agggacacga tgggcttcgc
     1141 cagcacgcat aataatcgaa tccagacgac gcagctcttc ctttaaaagc cctactgcgt
     1201 tggttaagct gtcaccacga aaagagttgg agcaaaccaa ttctgcaaaa tgggtggttt
     1261 tgtgttgcgg tgttgccttg acaccacgca tctcatatag cttaacagga ataccacgct
     1321 tagcaatttg ataagctgcc tctgatccag ctagaccagc accaataaca ttaatataag
     1381 attgagacaa tagaccaata cctctttggg gacttatcca tcactgattg ccccgcaact
     1441 ctttctttca agtaattacc ctgcctatta taacagaaat aagagcaaag caaaagaagg
     1501 agctgaacag cctcagtctt ttatataaag gagataagcc cgtacctgca cgctctccac
     1561 aaagctagct gcttcaagca ttttagcttt cgcccaatac cagctatcca catatcttgt
     1621 tcactgcagt agttactgga aggcttttta aggcttattt ttcaaaatct agccaaaaat
     1681 atttcaccgg acctcatcat cttgctggta gcagctaaac aagccttttc cagtaaaaaa
     1741 aaagcaagcg aaagcctgcc cttgttcttg tttagaaaaa acacatccat gctgcgataa
     1801 agacacttaa gacactaaac agcgatccaa tcaaataata ttcagcaaag gctgggcttt
     1861 cagagatttt attgtagcga gcaatagact tagcggtaag caccagtccg attgaagcaa
     1921 attgtcccaa caccatacaa acgcccataa caatacgctc taaattacca atagccgcac
     1981 ccgcccctac aatggtatcc attggtttat cactagctgg ctggaattta ttgaagcaga
     2041 gcttaaagat aatattgaca ggcttggtga tcaaaaccat aaaaagcact aacaataact
     2101 gccgagcatg taaccaatca gggatctcag cctgattaac acgagcgact aaagccagaa
     2161 taatgaaaag atgcaagagc tggtccaaca caaagaccca cgaccgatca agcttaatga
     2221 tacgagccca ttttggctta aaataatcaa taaccgcatg gctactaaaa ataaggatcg
     2281 ctgttagcca aagcttaggt atacacatca ccactagaaa caatggagca gctaccccta
     2341 ataagtgcag ccccagataa gcaagctgct cctccttctt atcagcaata acctgactct
     2401 gaaggtgata atctgataaa aaatgacaaa tcactagcag cactaaaata ggatgctgat
     2461 aaaggtaatc agataagccc tgcataggtg gctcctttcc tctttttatt cttgtaggta
     2521 ggtcaaagct gcatggcgac ttctaagata aacctttaca ctgctgcttt ttaagcgctt
     2581 tgacaaggca cttgattgga ggtccaatgt atcgccaatg agctgttggt caaattgttc
     2641 ttcatagatc cctaagtcta aaagcgcatg aaacacctct aattgactag cacgccagct
     2701 agcttttatc gcctcaccag ctgctaaaag gctattgagc accagatcct tgtgctcctt
     2761 atcagtccgt atagctacct gggtattgcc ataatcattt ttttgatgaa tgtaatgaat
     2821 agcctctctg gcacgccaat aggctggacc gtcagcacca atactaatat cagggttaat
     2881 atcagtcaaa atagtcccct gtccaatacc aaacctaaca gggtagcctg tcatggcttg
     2941 attaattaaa tcaatgagtt gaaaaacagg cgcatcatta gtcaacaagc cttgaaattc
     3001 atcacccaga gtcacagata agttagagac gatataggaa gaaaaatcat ggttgagctg
     3061 atccagacag gcctttaagg actcttgcac caaagaacgc gactgaattt gcttagaatg
     3121 gaccaaatcc ccaataacag cgatatatag catgattttc cctcctttta tgacttccat
     3181 tataacagac aaaaaccaaa aagtccatta taatggaaaa tcatctatat ttccgttata
     3241 atggacctct gctaaaatag ttcaaaccta ctttacaatc tcttctttat agtcacagac
     3301 ttcattgcta cacacaacct gcttacctcc acgaattttt ttctcaacaa ggtaatcgcc
     3361 tgacttcgga caagaccgtc ctaccggcaa atcccacgag gtaaagtcac actcagggta
     3421 gcggtcgcag ccatagaaaa tacggttacg ctttgttttg cgctcaatga cttggccttg
     3481 ctgacaagct ggacaagaaa ctccaatttc ctttgtgatg gcctttgtat gatggcactc
     3541 aggaaagtta ctacaagcat aaaacttgcc aaatctaccc agcttaacaa ccatcgggtg
     3601 gccgcacagc tcacaatcaa aaccagccgg ctcgtccttg atttgaattt tttcgatctc
     3661 cgtttcagcc ttggttaact ccttaacaaa tggcttgtag aattggtcaa tcacattctg
     3721 ccaggcttct ttgccgatct ctatctgatc aagcttatct tccatatcag ctgtaaattt
     3781 gacatcaaca atatcaggga agaattccac aatcaattga ttaacaattt cgcctaattc
     3841 cgtcggctca aagcgtttag cagccagctt aacataataa cgacgctgaa tcacatcgag
     3901 tgttggagca taggttgatg gccttccaac accgttttct tccagtgttt taatcaggct
     3961 tgcttctgaa taacgagctg gcggttgagt aaagtgctgt tcaggtgtta aggtaacctt
     4021 tttaaccact tctccttctg tcatttcagg aagcatcttg cttttatcag aatcattgta
     4081 aacagccata taaccgtcaa atttcatctg actgccattg gcaacaaaaa ggacactatt
     4141 ttgctctagg ttaaccttaa cagtatcaaa cacagcagct gtcatctgac tagcgacaaa
     4201 gcggttccaa atcaaggtat agagctttag ctgatcctta tctaaaaatt tagcaatagc
     4261 ctctggcgta tggttcacat tagatggtcg aatagcctca tgagcgtctt gagcaccagt
     4321 agcattttta actcgattgc catgcttaga gtactgacta ccgaaacgtt caacaataaa
     4381 gcctgcggca tcattttgag caactgggct gatacgagta gagtccgtac gcatgtaagt
     4441 aattaaccct tgtgttccat taggaccaag actaatcccc tcataaagct gctgagcaac
     4501 catcattgtt ttacgagtcc gaaagttaat cttattggct gcgtcctgct gcaatgagga
     4561 ggttgtataa ggtaaaggag catgacgcct gcgttctttt ttctcaacct tactaaccat
     4621 aaaatcatcg ctacttaatc gagacaaaac aagcttaaca tcatcattgg tattgagctt
     4681 catctttttg ccattgaggc cgtaaaagct tgcttggaat ttttttgtcc cttttttaaa
     4741 gagaccatca attgaccaat attcttcagg aacaaaggcc ttaatctcat gctctctgtc
     4801 aatgattagc tttagagcaa ccgattgcac gcgccctgct gaaagcccct ttttaacctt
     4861 tttccagaga attggcgaaa tggaataacc aacaatacga tccagtacac gacgtgcctg
     4921 ctgtgagtca accaaatcca tatcaatttt tcttgggcct tcaaaagctt ctttgacggc
     4981 atcctttgtg atttcattga aaacgacacg attgttatca tcaggatcaa gtcccaaaat
     5041 atgtgataaa tgccatgaaa tggcctctcc ctcacgatcc gggtcacttg ctagataaac
     5101 ctttttagca ttctttgctt ctttttttaa ggcattaatc agcggaccct taccacgaat
     5161 attaatatac tgtggctcat aatgattgtc aaaatcaata gacattgatg attttttcaa
     5221 atcacgaata tgaccaaccg aggcaacgac cttatactga cgtcccaaat atttttcgat
     5281 ggttttagcc ttagcaggtg attcaacaat gactagattt tttttagcag ctgctgattt
     5341 tttctttgta gcagatcttt tcgtctcttg ttttgactta gttgctgttt ttgttaccaa
     5401 ttgacacact tcctataaca gttatggtta aagcttctag cataatatcc cattttttaa
     5461 gaactgtcaa caaaaaattt tctataaata ggaagaaaag ttaagaatag tggtattctg
     5521 aaagaatgtc tctgccatga gtgacacagc tggcaccatc tttgatcagc ttcaaacagc
     5581 ccgccgatgt cccattaaga atattgtcag gtacgacaaa aatatcacgt ccctcttcca
     5641 tagctagctg acaggtaatc aaagagccag agcgctgctt agcctcaaca acaaggacac
     5701 ctcgactaag acctgcgata atacggtttc tttcagggaa atgataagac aaggcggcct
     5761 ctccagcccc atattcactg agcacgagat gacgctgaga taaaaactcc tgtagctggt
     5821 gattttcctt tggatagtag cgatctaggc cagtcccgat aacagctatg gtttgcccac
     5881 ctgctttcaa gcaagcgaga tgagcactgg tatcaatacc tctagcaagc ccgctgacaa
     5941 tgacaaagtg attcttaagc tctttgatga ttttgtaaac agaccgcgtc ccaatttcac
     6001 tggattctct agagccaacg actgccagct taggcttttc taacaggctt aaatcacctt
     6061 gataaaagag taaaacagga ggattataga tttccctcag ggccaatggg tattgcttat
     6121 ctaggataga taagctcgga aactggttga attccttttt taacaaggcg acatttaatt
     6181 gcttgtaggt ctcaataaat aaaactggat ttttgcagca agaaaccact gccatatctc
     6241 taagggatag agacttgtta ttacgctgct ggtagtcaat caggttaaga atatttaaat
     6301 tagttagccc agcctttttt aatttataaa gttcaaaatt attcatcact gtacctctct
     6361 aatgatttat tcgtaaaaaa attaaaaaag ctctgactaa acaaagcttt ttgcaaactc
     6421 ttgaggagct gtacaggatt ccagcaaaaa aatcgaggcc tcctagcctt tgtatgagca
     6481 ttgtagggca gctcatcaca tagcattcca ttgaaaaata ccagaattgt agatccacct
     6541 agtggctatc gtttttgctt tcggcagcta ccttttctca aaatgagatt tttagcgtaa
     6601 gatcattgat tttatcggct caaagctttg ccgatgaatt ggtgtgacac catactggtg
     6661 caatccctgc aggtgctcct tggtcccata gccggcattt ttagcaaagc catagcctgg
     6721 aaaggcctta tcgtaatcaa gcatcaatcg atctctggta accttagcca caatagaggc
     6781 tgcagcgatt gacatagagc tcgcatcgcc ttttataata gcctgttgag gaatagaaac
     6841 ctctagtgtc atggcatcaa tgagcaggta atcaggctta ctcacagagc cctccagctg
     6901 attaatggca gctgtcattg ctaattttgt tgcttcatag atattaaccc ggtcaatggt
     6961 atggttgtca ataattccaa gaccgattcc caacgctttc ttttgaatgg cttggtaaat
     7021 tgcttcatgc ttagctttag gaattttttt agaatcattt agccccttaa tggtgcagcc
     7081 ctttggcagt ataacacagg ctgctacaac tggtccagcc agaggacctc gaccaacctc
     7141 atctatacca gcaatcgctt gaaagccttt ttggtaaagc gcctgttcat acgtcaacat
     7201 cgcctcaagc cgggcttcct cttttaagat agcctctaaa gccctttttc tgctagatac
     7261 agccttttga acgccaagcc gcttatccgc ctttagctct tcaaaaaatg gatcagaaag
     7321 actagaaaca gcttctagac gagctttaat gtctttaata gtcattgctg tcatcatcac
     7381 caacctgatc taaggtgtac tgaccaagtc ttccatcacg aatatccttg atgaataagc
     7441 tgtaaaaacg atcatagtct tccttaaagc caagctgacg tgtcaaggac atgatgattt
     7501 ctggagcgtc agcctctaga tcaatagcct taaaacgctt taataggcga ttaggataat
     7561 acttcttaaa ataattcaat ccaaaaatcg tgacctcgtc cattggcaac agctgatcct
     7621 taatagcccc tgtcagggct aattttaacc caaccaattc gtcttcaaac tttggccata
     7681 agatacccgg agtatccaat atctctagtt ctttattgga ttttagccat tgctgtccct
     7741 tggtcactcc tggcttattg cctactgtgg caattttttt tcccgccaag cgattcatca
     7801 gggttgattt gccagcattt ggaatgccaa taatcatggt tcgtagcgtt tctttttgaa
     7861 tgcctcgttc tcttaagcga cgtagtttat ctgccatcaa ttccttagca gcctcggtga
     7921 cccttttgac cgtagcctgt tccttagcat tgatagctaa tgtcttaatc ccttgcttct
     7981 cataatattg ttgccatttc ttagtatgcg tgttatctgc tagatcagcc ttattaagaa
     8041 gcattagctt gggcttatct ccaacaattt tggtcagcat aggattttga cttgataaag
     8101 gtagcctagc gtctactaaa atcgtcacaa aatcaacatg cttaatattt tcctgtacct
     8161 gtctccttgc cttggacatg tgtccaggaa accattgaat cgtagccatg tgtgtaaaat
     8221 cctttcgtat caagggtttt tagcccctcg tcttttaaaa atcatgcgag tcaccaaaaa
     8281 atcaccaaat attaagcatt atctccagac caagcgatat aattgcaact tgttttggtt
     8341 atttttaatg ccaacaatat caaatgattt ctaatggtat ctggcttata gctattctct
     8401 gctgaataga ttgcctcttc aattttaccc tgtaatctcg ctcagcctgt ctcctgacct
     8461 tgcttttaca tatgaaactg taatattttc cattttacca gttatatgat aaagaaaatc
     8521 aaaatagtcg tagtagaata aattacttta aactattata gcacgatttc ccttatttta
     8581 ctgctaaatt atcctttgta aaagaagata ttaatcgtta taaagaccaa aaaagagaag
     8641 accaaaatga tcccctctag tcttcttttc ggcatatttt accgttattt ggccaacttt
     8701 ccactaatgt gagtaaaatt gtattctaag caagctttac ctattaactt aggagaaaac
     8761 ataatctcta tagctaaaaa taccaaaaaa attatgaatc attatcgcaa actatccata
     8821 gtgatcattt catcagccat ttcccatatt gctggattat gagttgctac gatgattaat
     8881 ctgttagcgt cacgaagaga cagtacaatc tccataatca acttggacgt ggttggatct
     8941 attgaagccg ttggttcatc tgccaaaata aatggcggat tttttaagat gatctttgct
     9001 aaggcaactc gttgtgacta acccccagat agctcaaaaa tgcgtttatc taggttcaga
     9061 taggataaac ctacacgttc taaggcctgt ttctgtctca tcgtttgctc agatttattc
     9121 aatttttgac caatgagacc aagtttgagg ttttcttcaa tcgtttgatt ttcaatcaaa
     9181 ccaaaatttt ggaataggta acccaattca tgacggaaaa aatcactaga tttatagctg
     9241 gctaagtctt tgtctcggta aaaaatagtc ccatgataag gttctaattt ccccatcatg
     9301 ttcatcaagg ttgttttccc gctaccgctt gaaccaatca aagcatagac ttttccaacc
     9361 tcaaatgtca ttgaaagatt agaaaatagc tctcgttctc caaaagattt actcacttgt
     9421 ttaagttcaa tcatgttaac ctcctttcaa aacaagcatg gacatcttgt tttctttctg
     9481 catttgaaca tgtaattgta aaagagatag gccagtgaag agcaacaata ctaagaaagc
     9541 aatcactatc tctacttgaa ggaatacact cgcaacaaat ccgagtaaaa agacacccaa
     9601 ttgagccagg aggtaattcc gatggatttc taaaaatctt agtccagcaa tacgtttgat
     9661 gacaatggca cgtctaaatt cttcaaagta gagcctattc atggtgttaa acaacaagat
     9721 tgaggttgct atcccaagca cagctcccgc aagcattatc caacgttccc tctggatatt
     9781 attcaacaat gtgatgtagt tctggtatcc tgattgcatt tctgagaccc aattttcaat
     9841 gccctgtctc tggataagct cctgggcatc ggacaactga ttaaagagga cataattctg
     9901 taccgcgtca aaccaaaaca tgacggactg aggtccagtt gactggggtg ttacgacaat
     9961 gataatcgga tctttcagaa actgttgata ggaaataggt gtcgtattat acacaaaacg
    10021 gtcttggcct gattccaaat aagccaccgt cgcaatcatt tgctgtcgac catcttgact
    10081 agacatgcga ctagttaagt cgtcttcaaa aacagatttg taatgttctt cctctgaacg
    10141 gagatgctca ggcaagagca agacaaattc ccctactgcg aggtgattca gtttttgttc
    10201 aatagccgta tctacaggga tgttttgacg ctccaagtat tgcggtgtga caataaggac
    10261 attgccattt gggctgtaat cttgccattc tgtagaagtt gtcaagtttt tggaaaagtc
    10321 ttagcctttg ttatcaatac ttgagtagca cctatgtttt tcagattagc ttgctcttgt
    10381 aactgttctg agctattaaa tgctgtcatt tcaacggtga tattttcagt tgattctgcc
    10441 tgcttgttat cttcttttgt tggagattct ggacgtttct caaaataaaa ataattataa
    10501 agctgttgag ccgttactcc tccaccagcc cagccagcaa caggttgacc attcttcaga
    10561 tatagtattg ttggtgttcc tgggattcca actgttttaa ataaaaactc ctgagct
//
LOCUS       DARYUW010000064        10491 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYUW010000064 DARYUW010000000
VERSION     DARYUW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10491
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            75..1238
                     /locus_tag="TVW11_001664"
     CDS             75..1238
                     /locus_tag="TVW11_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1365743.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(1361..3979)
                     /gene="alaS"
                     /locus_tag="TVW11_001665"
     CDS             complement(1361..3979)
                     /gene="alaS"
                     /locus_tag="TVW11_001665"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1365744.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(4335..5336)
                     /gene="prsA"
                     /locus_tag="TVW11_001666"
     CDS             complement(4335..5336)
                     /gene="prsA"
                     /locus_tag="TVW11_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1365745.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(5399..6106)
                     /locus_tag="TVW11_001667"
     CDS             complement(5399..6106)
                     /locus_tag="TVW11_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1365746.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(6189..6827)
                     /locus_tag="TVW11_001668"
     CDS             complement(6189..6827)
                     /locus_tag="TVW11_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1365747.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(6877..7509)
                     /locus_tag="TVW11_001669"
     CDS             complement(6877..7509)
                     /locus_tag="TVW11_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1365748.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(7499..8056)
                     /locus_tag="TVW11_001670"
     CDS             complement(7499..8056)
                     /locus_tag="TVW11_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1365749.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(8255..10057)
                     /gene="pepF"
                     /locus_tag="TVW11_001671"
     CDS             complement(8255..10057)
                     /gene="pepF"
                     /locus_tag="TVW11_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1365750.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(10047..>10491)
                     /locus_tag="TVW11_001672"
     CDS             complement(10047..>10491)
                     /locus_tag="TVW11_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1365751.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         3000 a         2451 c         2019 g         3021 t
ORIGIN      
        1 tgaggaaaaa tattgattta tttagcttta gtgataaaat gagggtgaaa aattaaataa
       61 aggaggacat tgatatgtct cagaagttgg gaaaacaact tattcgctct gttgttactg
      121 ccttagccgc catagcattt ggaatatttc ctgcaagcga gacgactaat catatcacct
      181 atgcagaggt taactcctta accccttcgg tagaatggcc tttagagcag tatcctaatt
      241 actatagcat agaaggaaag tctaatatca acaccaagga ttttcctaag ctatacacca
      301 ctaccgaaaa ggtttacaaa aaaagtggtc gaagcactaa gcgcgttact gtttctgatc
      361 tgcaatacgc tgcacttgat ggctatggcc gttcaggagc tgcctatggt attatcacaa
      421 aggatatgat cgcgatgtca gccggatacc gcgaaaaatg ggaaagcaat cctgagccaa
      481 gcggctggta tacatatcat ttcaaagaaa ctggcaagct agctactgag gccgactacc
      541 ttcacagcaa aagcaagatc aaacgaacct caaacaatag ctatgaaagc atcgtcctta
      601 gcaacggtaa gattcgcaac ggctatcttt ttgatcgtag tcatttaatt gctgacagct
      661 taggtggtcg tccttttaga aataatctca tcacaggtac acgtactcaa aacgttggca
      721 acaacgaccg caaggggggt atgcagtaca ttgaaaacaa agtcctaaac tatattaacc
      781 acaaccctca ggttcacgtt tattacaaag ccgtaccaat ctactcaggc tctgaattac
      841 tccctagggc cgttgtggtt tcagcgctct cctctgatgg taaaattgat gaaaccgtaa
      901 gagtctttaa cactgtcaat ggctttacca tcaattacca atatagcggc atcagccatg
      961 ataagggcat ggaggcttct agtgagtcag aagctgagga tattacagac gaaagcactc
     1021 cagtagctga accagctgat gaggaggcta tggagacaga ggctgctgct aacgacacaa
     1081 tagtctatgt tacaagtaat ggccaatcaa aggtatactg gtataataag gaccatctgc
     1141 cagagaaggt caatctcaat aaggttgtag aaatgaccga gcaggaagcc ctaaatcgag
     1201 gaaagcacca ttcctcctta gaaaaaataa atcaatagtc tcataacgac taacacaaga
     1261 gctggttgaa gcaaccagct ttttttgtgt gatgaaggat tagacagctc cttagctaaa
     1321 agataaagag gctgataaag cactcaacct cttatcgctt ttataaatgc tctggtactg
     1381 cggctaatag ctctgatagc ttgcttgcat cactaccacc tgccatcgcc atatctggct
     1441 taccgccacc acgacccgac acgattggcg ctaaggcctt aatcagattg ccagcgtgag
     1501 ctcttttatc cttacttgca acaagaacat tgaccttctc accaatgctt gcagccagca
     1561 caaggacatc tgaataatct ctttgcttcc aattatcagc aaaggtacgc aagactcctg
     1621 catctgatac ggatacctca ctagcaatgt aacgtagacc gtttgcttcc tggacctttt
     1681 taaagacatc accagcctga gctgctgctg ctttttcttt tagctctgcc atttcttttt
     1741 gcaaatcgcg gagctgctcg ctgaggctca caaccttact tggaagctgt tctatttgcg
     1801 gcaccttaag cgtatgtgca atttctttta ggatgtcttc ttgcttgcgg aagctttcaa
     1861 aggcctgctg acctgtcact gctatgatac gacgtgttcc tgagccgatc ccctcttcct
     1921 tgataatctt gaaaagacca atttctgatg agttggacaa gtgagtccct ccacaaagct
     1981 caacagaata atcgccaatc tgaacaacac gaacagtttt gccatatttt tcaccaaaga
     2041 gggccatagc tcccatagcc tttgctgttt caatatcagt ttctgtggtt gtaatagcta
     2101 atgccttcca gatttgctca ttgacctctt cttcaatacg acgcagctcc tgggctgtaa
     2161 cggcttcaaa gtgtgtaaag tcaaagcgta aaaaggcttc ttcatttaag gaacctgcct
     2221 gagtggcatg ttctccaata accttgtgaa gggcagcatg aagcagatga gtagcggtat
     2281 ggtttttctc aacagcatag cggcgcttgt gatcaatagc aagagtataa acagtgtcta
     2341 atgcaaggct tgcaagaacc tcaacagtgt gaagaggctg accattcggt gctttttgca
     2401 catctatcac acgagcaaca aggtcaccct tatcattttt gataacccca tgatcggcaa
     2461 cctgaccacc catttcagca taaaacggtg tctgatcaaa cacaagcaag gcctgtcctt
     2521 ctgaaaccat ctcactacgc tcattatcaa cgatgataac tgataagcga gaggcaacag
     2581 tctctgtttc gtacaaaaat tctgatggct ctgtgatgcc tgccagtgtc tcattttgca
     2641 tgcccattga gccaccctta acagctgctg cacgggcacg atcctgctgc tccttcatag
     2701 ctgccttgaa gccttcatga tcaatcttat agccagcatc ttctgctaat tcttcggtca
     2761 attcaactgg aaagccatag gtatcataca gcttaaagat atccttgcca tcaagcctgt
     2821 cttgcccctt ttcctttagc tgcgccagca attgatccaa atgccctgat cctgcatcaa
     2881 tggtacgtgc aaaggtttcc tcctcacgct tgataatttt ttcaataaag tcacgcttct
     2941 caagaatctc tggataatag gactccatga tatgacctac agtagctact agcttataaa
     3001 ggaaggtctc atgaataccg agcctacgac catgcataac agcacgacga agcaagcgac
     3061 gaagcacata gccacgacct tcattaccag gtagggcacc atctccaatc gcaaatgaca
     3121 aggcacgaat gtggtctgca atgaccttaa agctcatgtt gtcaccatct tggtcgtaag
     3181 tatggccaga tagcttttcc acttccttga tgatcggcat aaataggtcg gtttcaaagt
     3241 ttgtttttgc gccctgcata acagccacaa gacgctctaa gccagcaccc gtatcaatgt
     3301 ttttgtttgg aagctccttg tactctgagc gaggaattgt agggtctgcg ttaaattgag
     3361 acaaaacaat attccaaatt tcaatataac ggtcgttttc aatgtcctct tccagcaatc
     3421 taatcccaat atgatcagga tcataagcct caccacgatc aaagaaaatc tctgtatcag
     3481 gtcctgacgg gcctgcacca atctcccaaa aattttcctc taatggaatc aaatggcttg
     3541 gctcaacgcc cagagcaatc caacgattgt aagagtcctt gtcatctggg tagtaggtca
     3601 tgtataattt ttcctttgga aaatcgaacc attccggact tgttaacaat tcaaagcccc
     3661 actcaatcgc ttcgtcgcga aaataatctc cgatagaaaa attaccaagc atttcaaaca
     3721 tagtatggtg acgagctgtc ttaccaacat tttcaatatc gttagtgcgg attgactttt
     3781 gagcgttggt aatacgagga ttttcaggaa tgactgaccc atcaaaatat tttttgaggg
     3841 tggccacacc agagttaatc caaagcaggg ttgggtcatt gactggcaca agattggccg
     3901 aaggctcaat agagtgacct tttgatttcc aaaaatcaag ccacatttgg cggatttggg
     3961 ctgatgttaa ctgtttcatg attaagatac caagagcgat tagagagact gggtatgatt
     4021 gtccttagca taagtagcct ggggagacga tctctactcg cattcagttc ctttcgttga
     4081 ttttttatgg gattaggcta aaagccatca aaacaaaaca agcccatatc acagagggcg
     4141 aaaaccgcgg taccacctct attcaatgag cttgtcattc ttaattactt atatcagata
     4201 aaatcacatt aagcagcatg cctatcagat tatccgtaac tcacagcaac cgtcacttct
     4261 ctgggtcaaa tccttgataa acaattctta actaaaccag tataaagctt ttttgagcat
     4321 tcgtcaatga aaatctattt ttctgactta gatttagaag attgactatc cttgcttgag
     4381 tctgaagatg atttctgatc tgacttgctt gtgttcgcct tgcttgcttt tttatcagta
     4441 ttggcatact gtgccaagat attagcaaat gcttggtctt tgatcttaac atttgccttg
     4501 tctaaggcct ttgcaatgac cttattttgg aaatcaatgt tttgtgtctt ttcagccaag
     4561 acaatttctt ttagacgttt cttatatttc ttccaatcag aagccttttc ggcttttttg
     4621 gttaccttaa caatatagaa cttgttttga taagtagccg gatctaagac agaaaccacc
     4681 tctgaaatat caccctcttt taatcctgag gcggccttga tcacatctgc tggtaactta
     4741 gtgtctcctg agtcaaactt atagtctacc ttcttgtctg ctgctgttgt cttttcctta
     4801 gcaatagcag caaagtcagc accctcagcc ttaacctcac ctaaaacagc ctttgctgtt
     4861 tcttcattgt ctagagtagt gacctgagta gtcatttctg gtgtgtatga ctcataggct
     4921 tttttgtaat cagcatctgt cagctctttt ttagctgctt ctttaacagc atattcaacc
     4981 agcatggctg agcgaatttg acgcttgtag gtatctgttg tcaagccaga ctgcgcaagg
     5041 gctgcagaga atgacgcacc gtattgctca gctgatttat tgtaagcttc ttccgttctt
     5101 ttcttagaaa cctttttacc gtattggtcc tcaaaaacac gactaaccac aaggtttagc
     5161 attgctcttt gagaaatctc tgtatttttt gtttcattgt aaaaatcact aacactgata
     5221 gtgtcgccct tcatcgtaat gacacttgta ttgtcatttg tagactgaca ggctgctagg
     5281 gtcattgctg atgctagggt tacgatacca gcaagtaatt tagttgattt tttcatgtga
     5341 ttttgtgctc ctttttgtca ttaaccagta tattatatca caatttctta aacgtaactt
     5401 aatctaacaa acgaatatct gcttgatttt tacgaatcat cagcaagcca tcactaagcg
     5461 gcagcaggct ggctgtcaat ccaggattat caagagttgc tgcaaataag tcctgaaggc
     5521 cacgataaat cgtgcgctgt cctctccgaa cctccttgat cggcttagca atgtcacccc
     5581 cctgaaacac atcatctaaa acaaccattc cacctatttt taagtgcttt aacacctctg
     5641 gaagaaactg aatgtatttt gattttgcag agtccataaa aacaaagtca aactcgccag
     5701 taagtcctgc taaaagatca gccgcatctc cttcaagaag ggtaatttgc ttgcggctat
     5761 cgtattttgc aaaattttcc ttggcaaagc caatcatctc agcattgcga tcaatcgtta
     5821 taatctctgc ctcaggagca ttttctgcca ttagcaaggc agaaaagcca atagctgtgc
     5881 caatttctaa aatccttttg ggctgcaagc tttgcaataa aagcctgaaa taagcaacaa
     5941 cctcatgctg gataatggga atattttctt gtctggcaaa ggcctcaagc tctgctaaaa
     6001 agccttcgtt ttgctttagc tgcgttcgca tgtagtgaac aatgtcttct ttgacaatag
     6061 agcggcgcat attatgattt gcatttttac tatatgattt aaccatgcta tccattatat
     6121 aaaaaaactc taggtaatgc tagggctttc actagcctat tcacctttga cgatctgagt
     6181 agtatctatc aaaggagctc acagacagcc ttaagctgct tgacaatgct atcacaagca
     6241 gacaagtcct gtaagggata atcaggattg gcaaagccga tacaggtcat ctgagcagcc
     6301 ttagcagcct gactaccatg cttactatcc tcaatgacaa ggcaggtctt gggatcaacg
     6361 cttaaccatt cagcagcctt aagaaaaata tctggcgctg gctttgagcg agcaacctct
     6421 tcaccactaa ctaacacctc aaagcagtcc aaaagaccta gtgcagtgag atttctaata
     6481 atatctgcct taggcgatga ggaagctact gccaagcgat agcccttcgc atgcaggtgc
     6541 ttgattaatt gagcagcacc tgctatggcc ttgacaccgt cacgctcaag cattgcttga
     6601 cgacgatgat tcatctcagc gatgagggct tcaacagaat cctctagctg acactccttt
     6661 ttcatagttg tccacatatc gtcaaaggtg gttcccataa actggtactg atacgcttca
     6721 ttggtatcta tgcctcggtc caatagcatt tgtgtcttgg ttgacaaaaa gatatattct
     6781 gagtcaacaa tcacaccgtc catatcaaaa ataaggcttg ttttcatcat ctacctcctc
     6841 ttatgctata tctcagtcag gtcaagagca agactattaa ttactagagc tatttttacc
     6901 agaaaaaagc tcaacaatat ctgacagctg actaatatga tgattatcat cactatctgg
     6961 cagcaatagg ttgatagagc taatcccagc tgcccttgct gcagcaaggt ctaagggcct
     7021 atcaccaata tagtaggtct gcgacttatc catctgataa tgatgaatga gaaaaagaag
     7081 cgcttcaggg tccggcttac gcttaaagcc acaatctgct gtaatcacct ctgtaaagta
     7141 atcagcaatc cccagacgct gcaaaacagc ctgagtggtt cgtcctttat gagtcacaat
     7201 aaaaggctta accccctgct gagaggttaa ggctaatgtt tccttggctg taggcattag
     7261 tgctattagg tgatcacgcg cttcctgctc tcgggtaaag aaggccagca attctgaaaa
     7321 atccagctga tgtgcctctg ctaacctctt caaaagctgt ccgatggatt cttgaataat
     7381 cgtatccata acccaagcct catcaaaggg cagctgatag gtctgataca ataaacctag
     7441 cgcctgacga atagcctcag aggattggac tagagttcca tcaaagtccc aaatgagatt
     7501 aactgtcaca atccttacct cttaaatcaa tccaataacg agcaatagcc tgccctgcta
     7561 agcttgtagt agggtaatca tctgccacct gaacaatatc ctctaaaata ccaccagcct
     7621 tttcaatggt ttttcgactg gctatattat ctttattagc tgttattaag acacgcttga
     7681 tcccacgctc ttgatattgc tgtaatgcaa aggccagcaa gtctgtcata attccacgcc
     7741 cgcgataatc tgtccttgtc acatagccaa tatgtccgcc aattgttgct aagtctcctt
     7801 tttccaactg ccagcgacag cctattctag ccactagctg accatctaaa aaatagtaat
     7861 aattagtgct agtggaccag tcaggatgat cagtttggac ctcaaaccgt ctagattgct
     7921 caacaaaggc tgcaaagtcc tctacttttt tggtctcaac aaaggtatta cctgaagctt
     7981 tttcagctaa cagtatatcc tgaaagcgct taaaggctgc ttgatcagct aaagcaattg
     8041 ttctaatctc tttcatgcct ggctcctttt tattatgcta aaaatcaact gggcatttct
     8101 caagcattca tcatgccaac gaaaaagagc tgcccctaga actgttgatg taatactacg
     8161 tctagaggct gcccacaggc ctttaagcta ggctgataga cactgactgc tgctatttac
     8221 caatagctca aaacctaaga ggagatggca actattagag atgtgcccct cttgccacta
     8281 agtcctctag ctctgtcaaa cgctcttcaa agaccctaaa ggctgcttct aggtaatcac
     8341 ccttagccat atcaacacca gccttggcaa tcacctcaag cggataatct gaatttccag
     8401 acttcagata ggtcaagtag tgatcaatat cctcttgagt accatgcacg atcttatcag
     8461 ccaagtagct ggctgcagca aagcctgttg catattgata gacatagtag ttgtaataga
     8521 aatgcggaat gcgagcccac tcatactgga taaaatggtt gtcctctttt tttaagccat
     8581 aatatttttc gtttaaatca gcatagagat tattgaggta ttcacttgtt aacacctcgc
     8641 cattttgatc cgcctgatga atagcgtgct caaactcagc aaactgtgtt tgacgaaaaa
     8701 ccgttccacg aaaaccatct aggtaatgat tcaaaatagc aaagcgctcc ttatcatcct
     8761 gcacctcatg taacaaggcc tcagtcatga tattttcatt agtggttgaa gcaatctcag
     8821 ctaagaaaat gctgtaatct ccatacacgt aaggctgtgt ttcacgcgta aaggttgagt
     8881 gcaggctatg gcctgtctca tgcactagcg tatagaggtt atcaagcgtg tcctgccaat
     8941 ttaagagcat aaaggcattg gtatcatagg aaccaccaga gtaagctcct gagcgtttgc
     9001 ccttattgac atgcacatca atccaacgct ctgtaaaggc acgatgcaca cgctctgaat
     9061 aatcctggcc aaaaacagcc aaaaccttct ctgctttttc caaggcctca tcatagccga
     9121 tagcaagatc tgtctcagat aaaggagtat aaacatcata catctttaga tcatctaaac
     9181 caagcacctc ttgacgtagc ttcaaataac gatgaagcag cggcaaatgc ttattaacgt
     9241 tttctagtag ggtatcgtaa acagcctctg ggataaagtt ggctgacatc gctgcctgac
     9301 gggctgaagc atatttgtga acacgtgcct tataattttg cacctttaca ttggtttgca
     9361 gggttttagc ataggtgtgc tggaattgct cataagtact atacatggct tcataggcag
     9421 ccctacgcac cttgcggtct ttcgattcca tcaagctaat gaaattacca tgtgttagct
     9481 caacctcttc tcccttatca tttgtcacaa taggaaaagc aatgtcggca ttatctagga
     9541 tactaaaggt ctcctcagca ccattaaaga tttcttgtgc ccctgctaat agctcctcct
     9601 cagcctgact aaggacatgc tcacgcgtct tgaacaattt atcaaagaaa tggtcataga
     9661 ctgttagctc cggtgtctca gctaagaagg cttggtaggc ttcctgactt aaggccataa
     9721 attctggctc atagaatgaa aaggcttcac taaatttagc ataaatacca gaggccttag
     9781 cttgatattc ttgatacttg gcaactgtcg tatcctgatc atttttcatg ctagcataaa
     9841 cataaacctt ttcaacacga cgagccagct ccaaatgcag ctctgtgata tctaagagac
     9901 tgctgcttga atccaacaaa tgcccagcct gctgccttgc agcctcaatt gctgccagca
     9961 gactatctgc ctctgtctcc caagctgcgt ctgttgcaaa aatagtgctt aaatcccaag
    10021 tgtacttttc ctctagatga ctacgattat ctgtcatacg gacctcctaa gtttctatta
    10081 ctaatcattt taacataata tgctggtgaa aaaagctttt gcacctcttt atttgctgct
    10141 tttgcgtaat atttttcaaa gcaatcgtaa tagtggctca aatcctcatg aatctggcaa
    10201 aagccagctg agcaagcaat cggcttaacc tgtggataat aagcctctag gggcctatca
    10261 agcaggttat ccccagctag ataagcctct tcttgctttt tcaaccattt gctatctttt
    10321 gctagtaagg ctttttgaat ccttctcagc aagtgcttat ccatctggag ctgataggct
    10381 gacaggcctt ttctttggta aggcagccgc aaaaaggcca acaaatcatc atctaaggaa
    10441 caggtcttta ctagatagct gaccttacca aataaatcct catgaatcat a
//
LOCUS       DARYUW010000065        10308 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYUW010000065 DARYUW010000000
VERSION     DARYUW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10308
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..272)
                     /locus_tag="TVW11_001673"
     CDS             complement(<1..272)
                     /locus_tag="TVW11_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1365752.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFVNHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELS"
     gene            complement(275..625)
                     /locus_tag="TVW11_001674"
     CDS             complement(275..625)
                     /locus_tag="TVW11_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365753.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLEYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTTSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
     gene            921..1166
                     /locus_tag="TVW11_001675"
     CDS             921..1166
                     /locus_tag="TVW11_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365754.1"
                     /translation="MKKNIVDLQKRKEHFQWVADSLEGKENELYVERDWYDNPTLISK
                     EDAKKEVEQIRQELILLQNKSFIEYILQLLHQLFHRQ"
     gene            complement(1117..1905)
                     /locus_tag="TVW11_001676"
     CDS             complement(1117..1905)
                     /locus_tag="TVW11_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365755.1"
                     /translation="MSRYSDYKYANTILKSIEERPEKYLIIHYSCESFYNLGGKSPRI
                     ASISVRQFNNAQTNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWI
                     HWNMRDTVFGFHAIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLL
                     ELNNLTPHRFLTGKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKW
                     KMRGTNLSGLLSTFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
     gene            1956..2147
                     /locus_tag="TVW11_001677"
     CDS             1956..2147
                     /locus_tag="TVW11_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1365756.1"
                     /translation="MPDIAVGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGST
                     RGPKANQFILRVIADYSIE"
     gene            2228..2539
                     /locus_tag="TVW11_001678"
     CDS             2228..2539
                     /locus_tag="TVW11_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEL1365757.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWAAEM
                     RDHPDFKQFINNPTHRIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     A"
     gene            2541..2711
                     /locus_tag="TVW11_001679"
     CDS             2541..2711
                     /locus_tag="TVW11_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365758.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            2704..2907
                     /locus_tag="TVW11_001680"
     CDS             2704..2907
                     /locus_tag="TVW11_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365759.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            2904..3290
                     /locus_tag="TVW11_001681"
     CDS             2904..3290
                     /locus_tag="TVW11_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365760.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELLTLNDVERYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            3434..3637
                     /locus_tag="TVW11_001682"
     CDS             3434..3637
                     /locus_tag="TVW11_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365761.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            3725..4024
                     /locus_tag="TVW11_001683"
     CDS             3725..4024
                     /locus_tag="TVW11_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365762.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            4024..5181
                     /locus_tag="TVW11_001684"
     CDS             4024..5181
                     /locus_tag="TVW11_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1365763.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            5190..5753
                     /locus_tag="TVW11_001685"
     CDS             5190..5753
                     /locus_tag="TVW11_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1365764.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            5796..7718
                     /locus_tag="TVW11_001686"
                     /pseudo
     CDS             5796..7718
                     /locus_tag="TVW11_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
     gene            7723..10107
                     /locus_tag="TVW11_001687"
     CDS             7723..10107
                     /locus_tag="TVW11_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1365765.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELSYENKNVKSGGKQAKNWVGFKLKSEF"
BASE COUNT         3361 a         1794 c         2329 g         2824 t
ORIGIN      
        1 gataactctt cttttagcaa gtgatgaatc atatttctgt ctgcttctaa ttcacacagt
       61 tctctattta gttcatactg tctgttggta tgctctttat gaccgatttc atgatatatt
      121 gctttctttt tttcatgatc atcaagataa gaaccaatac caagaacttt gcagtcatgg
      181 ttaacaaacg cttctttatc tgtgccacgg ttatcataaa ataaaagctc ataaccgtga
      241 cctttgacat actcttgaag tgataagtcc atagttaatc tctattcttg aatctttgtt
      301 ctaagactgc tgcaatgaga tcaatatcat catcggtaag tggttttcca tcataagaca
      361 ttgactgagc agctatctct ttaaagtcta ttgttttttg actagtggtg ccattagcaa
      421 tagcaggatt atcagtgcga ccaagcaaat aatctgttga aacattgaag tagtctgcta
      481 tttcagcaat tctttcagcg ttgggttttt gagttttcaa cttatagagt gtatttcggc
      541 tatattctaa agtttcctct agttgaataa gtgtaattcc acgctgtttg cacaattctt
      601 tgattttttc aaacgtcgga aacattgatt tatcaacctt tctaaggcat gacaaaaaat
      661 atttcaactt tttgggtgaa aaatgttgac aattcaacca aatgggtgta tcatattttt
      721 tgtaagcaag agataactaa aaaaacaact aagcaaacaa ctataaaaca gttttggcga
      781 acgagtttaa gttgatttgt taaggttctt taatatgctt taattctaac tttttaggtg
      841 tgagttgtca agtggtcata tactaaaaag ttgaaaattt agttatttct tgtttacaaa
      901 ttttaaaaca aggaggaaaa atgaaaaaaa acatcgttga tctacaaaag cgtaaagagc
      961 attttcagtg ggtcgctgat agcttagagg ggaaagaaaa cgaactttac gtggaaagag
     1021 attggtacga caatccgact cttatttcca aagaggatgc aaaaaaagaa gtagagcaaa
     1081 tacgacaaga acttattcta cttcaaaata aatcatttat tgaatatatt ttgcaattat
     1141 tgcaccaact attccaccga caataaggtt gattataccg attatcactt ttcctgagat
     1201 tgtttcttga aaagtggaaa gtaatccaga taggttagtt cctctcattt tccatttagg
     1261 ggtgttagtt tttaaatcat cgttgatagc taaagtgagg aatgttgaaa agctattgac
     1321 cttgcttgat gttgacatac ttagttcatg gtattgtctc gaagagaaag cgtcagcttc
     1381 ttgtttacct gtcagaaaac gatgtggggt tagattgttc aattcaagta atttttcaat
     1441 atgcggattg tcaatatatc ctccaccgta catcttttta aacagatagg ctaaatcgat
     1501 ctttttgtca tcatcaatga ttattggtgt gccgcctaga actttgaatc gctgctcaat
     1561 agcatgaaag ccaaagacag tatctctcat attccagtga atccaatttt tgtcggtatt
     1621 tctgtcaaca aatgtgaaga aatctgttaa cagctctttt tcgatagttt cataagtatc
     1681 atcagtaatt ggggtatcta atatctcgga gtactgatga atggaaaagt tgttggtttg
     1741 ggcattattg aattgacgaa ctgaaatgga agctattcta ggacttttac cacctagatt
     1801 ataaaaactt tcgcaggagt aatggataat cagatatttt tctggtcgtt cttcaatact
     1861 tttaaggata gtattagcgt atttataatc agagtatcga gacattttta cctcaagttt
     1921 ttatttttat tatatcagaa aagaaaggag aaaatatgcc agatattgca gttggacgag
     1981 aaaaagttgt taccttccta aaaagtaaca atatcaagaa gagtgattta gcagcagcct
     2041 atggtctcaa tcgtcaagag gtcactaaca ttcttagtgg ctcaactaga ggaccaaagg
     2101 ctaaccagtt tattctgcga gtgattgcag attacagcat tgagtaaatg caaaaaaaag
     2161 gaactgattg cagtcagccc cttatcaaaa attctactta cattatatca cagattggag
     2221 gtaagaaatg ccaaaagctg aattagttta cagaccagct aagcaatctg aaaaagcaga
     2281 agctggtgac tatgaacacc tttgccaaat ctgggaaggt ttaacagtcg gaacggccaa
     2341 ggtttgggcg gcagaaatga gagatcaccc agattttaaa caatttatca ataatccaac
     2401 gcatagaatt gtattcattg attacgaagg tttccgttta tttgttaaat ggaaaagtcg
     2461 taaccgctat aaacccaaga aggaaaccct ggcagaaatg cttgaaaata ttaaattcga
     2521 aaaaagagta ggagcataac atgaacaaat tagaattatt tttattagta acaactgttg
     2581 ctttagcaat tgttgccagg atacaatatg aagtcatcaa aaaacacaac tcgccagaga
     2641 ataagcgaaa aatttttagg gaagtagctt tagaaaacag caagaaatgg agtgcagaac
     2701 gttatgtcta aatgggaatt acaaaaacaa ctactggaaa atgcgacaga ttttgagagc
     2761 acagttgagg ctttacttga cttaaacgag tctggcgaaa tatctgatct ggaactctta
     2821 ctgaacttaa aggataaatt cagaagctat tccaaagaaa aaatacgtat ccttaatgaa
     2881 attctcaagc taggaggtgc agaatgatga caacttttga aaagattatt aagaaaatta
     2941 atcggattga gggggagtta gttaaacctg aagctgaaag acgagatagc ttacctatcc
     3001 tatctgctca gttgggttct attaaacaag atttaaaatt gatgctttgg attgagctac
     3061 tgacgttaaa tgacgtagag agatatgaag ctctttatca aggaaatgat tttaaattca
     3121 gtgaaacttt cttagagcgt caagcgacga gaaaagcctt ttggagacga ttagctaaag
     3181 aaactttcaa agaagaccag gataagagga actttgttaa gttggctgag aaagaattta
     3241 aaggtgcaac tttgtcatgg caagaatttt tgtggggtaa aaagaaatga atatatcact
     3301 aaaatttatt gatgaaaccc tagctggctt aaatgatatt ttacgtcagg gggggctctt
     3361 gctcccaaaa ccaagcctta gcagacgcag tttttatact aacagcttta aaacaagtaa
     3421 ttgaggagag aaaatgaact atttagaata cgcactagtt tatcttgaac gtgagttaga
     3481 aattattgat aacgaagtta tcgaagttga gttgccgggc ggagattggg agtttgtgcc
     3541 taatccctac tacgagaaag gtctacatga tagcccacac tatcgtagtc aggttgctaa
     3601 agacattctt gatattaaag gacttttggg gaggtgaggc tattgattgc atcaaaaaag
     3661 acggcttagg aaaccgtcaa caattataca caattaaatt ataacacaga aagagagaaa
     3721 cacaatgatt gaagtaactt ttaaagcaga gagcatggca ggtgttttcg atgctatgcg
     3781 tgaagctctg gatatgccga agacagtaac caaggatgtt gttgaagaaa aaccagctcc
     3841 taaaaagaaa gaagagtctg taactttgac attagctgat attaagaaaa tggctaaagc
     3901 caaggttgaa gaagggaagt caaaggacat caaggaagtc ttgaaagaga tgaacgtcgc
     3961 aaaagttggt gaacttgaag aataccagtt tgctgagttt gttgagaagt tggaggccct
     4021 ctaatgccag tagaaaatca cgcactactg tctgcttcta gtgctcacag atggctttat
     4081 tgccctatgc tgccgagatt agaagcagac tatcctagcc gcgataccgt atacactcaa
     4141 gagggcacaa gcgcccatga gctttctgaa atcaaactga tgtacaagtc tggtaaaatc
     4201 accaagcgta aatttaacac gttaaccaag gcttttaagg aaaactcaga cttctacaac
     4261 gaagagatgg aagagatgac ggaactttac acagatattg ttatggagca cctaaatgct
     4321 tatgagaacg ccgaaattga acttgaaaaa cgggttgatt ttagcgactg ggtgcctggc
     4381 ggttttggga cttcggatgt tgtcatttta gcggatgggg tcattgaaat tattgatctt
     4441 aagtatggca agggcatgcc tgtgtctgct aaccaaaacc cacagatggg gctgtacgct
     4501 ctaggagctt atgcttccta cgatatggtt tatgactttg accgtatcaa aatgaccatt
     4561 attcagccac gtttagattc ggttagttct gttgacattt acgtggagga gttactctac
     4621 tgggcggata atgttgtctt gcctatggcc gctcaagcag acgcaggcat tggtgactgg
     4681 aacctaagtg aaaaagtatt gcagtggtct cctgtcgcag ctaaattggt accaagagcg
     4741 caagaaaatt gggaattaat tgataaatat gactatcagg agcctgtcta tttatctgat
     4801 gaagccgtcg cagagattct tgacaaagcc tcagctatca agaagtgggt tgagtcagtt
     4861 gaagcctatg ccctgaaaga agcactctcg ggaaaagaag ttccaggcta taagattgtt
     4921 gaaggtagaa gtaatcgagt catcactgat aaagacaaag caattgatat tttacaagat
     4981 aacggctttg acgatgagat ttttaaaccg aaagagctgt tagcaatggg aactcttgaa
     5041 aagttaatag gtaaaaccac ttttgctgat ttattagcag aagtaattga taaaccacag
     5101 ggcaaacctg tccttgttaa aaatagcgac aagcgacccg cattaaatag cttagaacaa
     5161 gcaattaaag attttgaata ggagaaatta taattatgac accaaacaca actaaagtag
     5221 taaccggaaa agtacgccta agctatgtag ctttactaga gcctaaagcc tttgaaggtc
     5281 aagaggctaa gtattcaaca gttatcttaa ttccaaaaac agacaaagtc acaatcaaga
     5341 aaattaaaga cgcgcagaaa gctgcttatg aggctgccaa ggacaataaa ctcaaagggg
     5401 ttaaatggga gcgcgttaag acaacgcttc gtgacggcga cgaagaaatg gataccgaag
     5461 agcacccaga gtacgctgga cacgtgttca tgtcagtgtc aagtaaaact aagccacaaa
     5521 tcattgacaa gtataaaaac cccgttgact cagcggatga agtttactct ggcgtctatg
     5581 ctcgcgtatc acttaatgcc tatgcttaca acacagcggg aaataaagga atctcttgcg
     5641 gattaaacaa cgtccaaatt gttgctaaag gagactacct tggcggccgt tcgtcagctg
     5701 atgcagattt tgacgagtgg aacgaagaag aggacgaaga cgacatttta tagtagaggg
     5761 cctctttaga ggctcctcat ttttaaagga gaggtatgag acatttaaat attgatattg
     5821 aaacctatag ttcgaatgac atcaaaaatg gggtttacaa gtacgctgac gcagaagatt
     5881 ttgagatttt acttttcgct tactctatag atggcggaga agtagagtgc cttgatttga
     5941 caaggcagtc tctacctgaa gacatcaaag atatgttatt tgatgataaa gtccgaaagc
     6001 acgcctttaa tgcccaattc gaaagagttt gtctcagtcg ttacctcggt ctaccttact
     6061 atctagatcc ttgccaatgg caatgcacca tggtgctggc ccaagagttg gggctgcctt
     6121 caagcttgga aaagtgtgcg ctgtatttaa aattagtgca ggaaaaagat acctcgggta
     6181 aaaacttaat cagatacttt tccctgcctt gcaaaccaag taaagctaac ggtgggagaa
     6241 ctagaaattt accagaacac gcccccgaaa agtggtaaat gtttattgac tactgcatcc
     6301 aagacgttgt tgttgagatg gcaattgccg aaaaactaga gtcagttcct gtgcacgacc
     6361 gtgaatggga ctactacgca tgcgaccaga gaatcaacga cagaggcgtg gcgcttgata
     6421 aagagttagt tgcttcggcc ttgtattgca aagatgttaa gatggaaagt ttgtctggtg
     6481 aactaaaagc tctaacagga cttgataatc ctaatagcag ggcgcagttg ttaccgtggc
     6541 taaaagaaca cggttattcg gttaatggtc tgactaaagc ggatgttgag caggagctta
     6601 agacggccga aggagaactt aagagagttt tagaacttaa actacaaacc gctatgtcaa
     6661 gtctaaaaaa atatgaagct atggaaagag ctatgtgctc agacggacga gttcatggac
     6721 tacttcagtt ttacggagct agcaggacag gaagatgggc gggcagagtt gtccaagtac
     6781 agaacttagc taggaattat ataaaggatc tagatgatgc tagagagtat gttaaaaagc
     6841 gtgatattga tgctgtggag attttatacg atagtcttaa cgacacttta aagcagctag
     6901 taagaacggc actcgtggcc aaagactgct gtaccttcta cgtctctgac ttctcagcga
     6961 ttgaggctag ggtgattgcg tggtttgccg gagagcagtg gaggcttgac gtgttttcga
     7021 cgcacggaaa aatctatgag gcatccgcta gccagatgtt cggaattcca attgaggaga
     7081 ttgataagga actacgccaa aaaggcaaaa tctcagagtt ggcacttggc tatcaaggag
     7141 gtcctggagc gctcaagcag atgggagctc taaatatggg agtcaaggaa gaggagctcc
     7201 aagggctagt tgatgactgg cgcagggcca ataagaaaat cgtccaattt tggaaagatg
     7261 tgcagagagc cgccatcaaa gctatcaaat cgagagcacc aataaaactt ggaaaactac
     7321 gatttagata ccgtaaaggt ttcctcttta taacattgcc tagcggtagg aacttagctt
     7381 atgcaagagc caaggttgag ccaggcgact atggagacaa aatcgtctat gagggccaag
     7441 gagataaggc ctacttcaca gcgcaagaga cttacggcgg taagcttgtc gaaaatatcg
     7501 ttcaggcgac ggccagggat attctagctg aagcgcttct gaggattgaa gctgcaggct
     7561 atggtgttgt tttccacgtt catgatgagg ctattatcga aggctcaggc ctgacaatcg
     7621 aagaagttaa tgatttgatg gctcaggctc ctgaatgggc ggagggtctt cctttaaata
     7681 gcgaaggcta cgtaacaaag tattatatga aggattagat agatgaagca agaaaaacta
     7741 atagtaaagt cttctcctct gcaagagctt catatcgcaa cgggtaattc acgaacagct
     7801 aagacgtgga aaaatattac gctaacttgg caggagctgg ttgagaggtt agagaaacct
     7861 acagtcaccc aagagacgtt tgcggagtac cagaagatgt ctcgagcaga aaaagggcaa
     7921 gcaaaagacg taggaggttt tgtcggcggg tggctaaagc agggtaaacg gaaaaacgaa
     7981 aatgttcaaa gtaggtcctt ggttgcgctt gacgcagata gcccaagtaa agatttctta
     8041 gataggctag acctgcttgc agactatgca tacgtactct acagtactca cagccactca
     8101 aaaaaagctg ctaagtaccg tcttattatc cctactgacc gtttaatgat gcctgatgaa
     8161 tatgagccag tcgctaggta cttggctaat caactaggca tgtcgaactt tgatgacacg
     8221 acttatcaaa gtgtgcgttt gatgttctgg ccgagccact cgagagatgc tgactttacg
     8281 tttaaatata acgatgaggc ttttctaagt gttgatgagg tgcttgatac atacccggac
     8341 tggcgtgact caagcttctg gccagaaagc ccgacgcacg ctgttaaaag acagcgtgaa
     8401 gctaaaaaac aaggtgaccc acttagtaaa aaagggctta ttggagcctt ttgtcgtaac
     8461 tatgacatta gacaggccat tgcaacgttc ttgcccgagg tttatgaaga aggaacgact
     8521 cctgataggt acacctacac tgagggttca accgcaaatg gcttagtcat ctatgatgaa
     8581 gtcttcgctt atagccatca cgggacagat cccgtggggg atacgcttgt aaatgcatac
     8641 gaccttgttc gtatccataa attcggagag caagatagcg aggctaaaga tattactcct
     8701 actaataagt tgccatcaag taaagcgatg aatgcttttg tctctgactt acccgaaatt
     8761 aaagactatt taatggcgga ggctttaggc gattttgatg aagagttacc agtcgaagat
     8821 gacagaagct ggcttgaaat tgatgagagg ggcgaacctg aggtcaatag ttatttgcta
     8881 gcaacgcaga ttattaagga ggttccgatt tattgggacg gcttagaatt tttacgctac
     8941 gacgctaaaa aaggcatctg gttgccaaac gcagaggagt atttgaagag ttatatctca
     9001 actaagaaac tcggtaaaat tactaagatt aggcacatta gcgaaaccgt cgtagcgatt
     9061 aaggcacagg ctttctcaag cgaagtgttt actgagagcg atcttaacaa gatagtgcta
     9121 gcgaacggag tctatgactt gagggataac agttttaaga ctaagtttga tccagaattg
     9181 catgcaaggt caagccatcc cgttgtctat gaccccgagg cggcctgtga aacctttgag
     9241 ggttttctta gggagaccgt cggagctgaa aatatagatt tcatctttga gtggttcggc
     9301 tataactttt atcgcgaata tgctatccaa aaaatgctat tcatctacgg cagcggcggt
     9361 actggtaaat caacactgat taatatttta cgtgaaatga taggtgctga taattactca
     9421 gccgtgacac tgcagtacct gatgcaagaa cgctttgcaa aaatcggctt atatcgaaag
     9481 actgctaact tcgataccga tgctaaacct caatacttag cagatggcgc aacacttaaa
     9541 atgttgacgg gggaggatac tattcacgca gaccgtaaga ataaagagcc gattaacttt
     9601 tacaattatg ctaagctgtc ttttgccatg aatgagctcc cacctatgcg agatttcagc
     9661 ggaggactta aacgccgcat gatgatcctc gagatggata aggttttaac gcaggaagtt
     9721 aaggcgaaat acccgctaga taagattatg agcgaggtgc caggtatctt taatagggcg
     9781 atggaggggc ttagaaaggc cttaagtaag agagatttca gtattagtgc cagcatgaga
     9841 tcaagtgtcg agaaatggga aaaaggcaac gatgtcgtgg ccatgttcct tgaagacgag
     9901 tgtgaacttg gtgaagactt caaagttcct gttagggatg tctacccagc ctacaagttc
     9961 tattgtcagg attcaggcta caaacctttg gcaaaaaatg catttaacca ccgactaaga
    10021 gagttaagtt atgaaaataa aaacgttaaa tctggaggaa agcaagccaa aaattgggtc
    10081 ggttttaagt taaaaagtga gttttagggg ttactttttt gggattagag tttggtaacc
    10141 ctagaaaaaa gttaccaagt taccggtttt tcaaacttta aaaataaaaa atttaaaaat
    10201 aatttttaaa aaatcaaaac tgaattggaa aaatcggtaa cttagtaact cgacccttag
    10261 aaatgggctc gaaaagtagc cctggtagct tattggtagc cctaagaa
//
LOCUS       DARYUW010000066         9761 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYUW010000066 DARYUW010000000
VERSION     DARYUW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9761
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            97..834
                     /locus_tag="TVW11_001688"
     CDS             97..834
                     /locus_tag="TVW11_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1365766.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            873..1373
                     /locus_tag="TVW11_001689"
     CDS             873..1373
                     /locus_tag="TVW11_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1365767.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            1392..2081
                     /locus_tag="TVW11_001690"
     CDS             1392..2081
                     /locus_tag="TVW11_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1365768.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            2475..2717
                     /locus_tag="TVW11_001691"
     CDS             2475..2717
                     /locus_tag="TVW11_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1365769.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            2897..3691
                     /gene="racE"
                     /locus_tag="TVW11_001692"
     CDS             2897..3691
                     /gene="racE"
                     /locus_tag="TVW11_001692"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1365770.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            3688..4677
                     /locus_tag="TVW11_001693"
     CDS             3688..4677
                     /locus_tag="TVW11_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1365771.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            4653..5174
                     /locus_tag="TVW11_001694"
     CDS             4653..5174
                     /locus_tag="TVW11_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1365772.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            5171..5632
                     /locus_tag="TVW11_001695"
     CDS             5171..5632
                     /locus_tag="TVW11_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1365773.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            5629..6375
                     /gene="xerD"
                     /locus_tag="TVW11_001696"
     CDS             5629..6375
                     /gene="xerD"
                     /locus_tag="TVW11_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1365774.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            6375..7082
                     /locus_tag="TVW11_001697"
     CDS             6375..7082
                     /locus_tag="TVW11_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1365775.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            7079..7618
                     /locus_tag="TVW11_001698"
     CDS             7079..7618
                     /locus_tag="TVW11_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1365776.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            7855..8577
                     /locus_tag="TVW11_001699"
     CDS             7855..8577
                     /locus_tag="TVW11_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1365777.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            8574..8852
                     /gene="yidD"
                     /locus_tag="TVW11_001700"
     CDS             8574..8852
                     /gene="yidD"
                     /locus_tag="TVW11_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1365778.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            9011..9559
                     /locus_tag="TVW11_001701"
     CDS             9011..9559
                     /locus_tag="TVW11_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1365779.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT         2731 a         1868 c         2324 g         2838 t
ORIGIN      
        1 acgacacctg ataaggggag aaagctcctt ttaggctgat agccttctga tggtttttat
       61 gcaaaagagt gaacaatttt gtgatataat aagaccatga ttatcacatc aaaagcaaac
      121 catttgatta agcaggctaa gaaattactg caaaaaaagc atcgcaagca ctcttacttg
      181 attgagggct ggcacctatt tgaggaggct cagagatctg ggcaggaatt gatacatatt
      241 tttgttctgg aggaaatggc agagcgctta tcaggctttg atcaggttgt catcgtcagt
      301 ccagagattc taaaggagct gacgagctct cccaatccac agggcattat tgctgaggtt
      361 aagctttgtc aacaggcctt accgactagc tatgctggaa aatatttgat tttagaggac
      421 attcaggatc caggcaatct agggacaatc attagaacag cggacgcagc aaagtttgat
      481 ggggtgtttt tgtctgagaa gtctgcggat gtctacaatc aaaaaactct acgctccatg
      541 cagggcagtc attttcacct gccgatttgg cgaacggata tttatcaggt cagtcaggtg
      601 atgcagcagc aaaaaatacc agtgctagca acgaccttgt ctcaggattc gattgattac
      661 aaggacctct cagctaggag cagccttgcc cttgttttag gaaatgaagg tcagggcatt
      721 agtcctgaga tggcagcttt ggctgatcag ctgattcata ttagcatgcc tggacaagct
      781 gaaagcttaa atgttgcagt tgcagcagga atcctcattt tcagcctaat ttaagctagt
      841 atggtataat aatgatgtga ggtgattagt gtatgcatta tacagaagat acagaataca
      901 tggagcatgt tggtcatttg attgctcacc ctcgctttca aaggcttgga gatattgttc
      961 agcatcacca ttctactcgc ttagagcact ctgtcaatgt ttcttattct agctataggc
     1021 tggcaaagag gcttggctta gacgccaaga gtaccgcacg aggtggcttg ctacacgatt
     1081 tcttttatta tgattggcga gtaaccaagt ttaacaaggg acacgcttgg gtgcacccta
     1141 gaattgctgt tcgaaatgct aaaaaattaa cagcactcaa caaaaaagaa gaggatatta
     1201 tcctaaagca tatgtgggga gctactattg cttttcctcg ctataaggaa agctatattg
     1261 ttacctttgt tgataaatat tgggcggtca aggaggccat gacgccgctg cgtcaaaaat
     1321 ggacgaaccg tcgcttcctg cgtcgaaaga cgcttcaaag tcacaatcat taagtaaaaa
     1381 aaggagttat gatgaacgat aatgttattt acacacagtc tgacgcaggc ttgagccatt
     1441 tttttgccaa ggtctatagc ctggttggta tgggagttgg gctttctgcc tttgtttctt
     1501 atttgatgct gtttccattt aggcaaaatt tagtctcgat tgttcttgat catcctatgg
     1561 tctattatgg ggcggctatt gttgagcttg tactggtttt tgttgctagt ggtgctgcac
     1621 gtcgcaatac accagcagct ttacccttat ttcttgtcta ttcagcctta aatggcttta
     1681 ccttgagctt cattattgca gcttatgcgc aaacaacggt gctacaggcc tttatctcat
     1741 cggcagctgt tttctttgct atgtcactgc ttggtgttaa ggttaagcgt gatctgtcag
     1801 gtattcgaaa ggccatgttt gcagccttga ttgggattat cgtggctagt ctggtaaatc
     1861 tctttatcgg tagtgacctg atgagctatg tgatcagcct tatttcagtg ttgatctttt
     1921 ctggcttgat tgcttcagac aatcagatga tcaagcaggt ctaccaagcc tctaacggtc
     1981 aggttggtga cggctgggct gtcgctatgg ctcttagctt atacctagac tttatcaacc
     2041 tctttatcag tctacttcgt ctcttgggaa gaaatgacta atagctattt taagcgcagc
     2101 tgctgattgt cacttaatcg ctattacgag aaatcagcga agctgcaggt gttacctttt
     2161 gttagaaaag agtggctgct gctagtaaga aagtagctgc taggagagcc tgatgagcgt
     2221 gactgtcaag gaaggccagt tactattgct accatctagg gaaggtacca aaaaaagtca
     2281 agaagcgggc ccaagggctc gtttttgttt gcttgatttg tggtaaagtg cttcaaacca
     2341 agcctatatc tagtctgata gctcttatca gctgacaaca tcatatttac aatgcctgtt
     2401 ggtgtagatt tgtaaagcat gctctttttt ggtataatga gaggaacaaa aaatcgagga
     2461 gaatatctat caatatgtct acagctatct ggatattatt aatcattgtt gctcttacag
     2521 ccggtctttt tggtgggatt tttattgccc gcaagcaaat tgaaaaggaa attggagagc
     2581 acccacgatt aacgcctgag gccattcgtg aaatgatgag tcaaatgggt caaaaaccaa
     2641 gtgaagcgaa aattcaacaa acttaccgca acattgtcaa gcaatcaaaa gccgcaatga
     2701 ctaagggtaa aaaataggtt acggattaga aatcgtggtt tctaagcaat agctaagagt
     2761 gaacagtctt tgatgttaaa agcttgttta gagcttgcat tgtcagttag aggtgtcaac
     2821 tgttcagggg ttaacaatag actcagttgg ctcttaccag ctgagttttt tatgcttcaa
     2881 tgaggaaata atcgttatgg acaatagacc aattggtttt ttagattctg gtgtaggagg
     2941 cttaactgtt gttagtgagc tgatgcgtca gcttccccat gaaaaaatca tttatattgg
     3001 tgattcagca agagctcctt atggtcctag acctgctgaa caaatcagag aatatacctg
     3061 ggagttggtt cgttttttat taacgaaaca tgtcaagatg attgtctttg cttgtaacac
     3121 tgcaacagct gttgcttggg aggaggtcaa ggaggctttg gatattcctg ttttgggcgt
     3181 tatcctgccg ggcgctagcg cagctatcaa ggctactagt ggaggaaagg ttggtgttat
     3241 tggcacatca atgactattt cttcaggcat ttaccaggaa aagatccagt tgctggctcc
     3301 cactgttcag gtaactagcc tagcctgtcc tagatttgtt cctattgtgg agtccaatga
     3361 gataagctca agtgtggcca agaaaattgt ctatgaaacc ttggctccct tagttggaaa
     3421 gatagatacc cttgttttgg gctgcaccca ttatcctctt cttaggacga ttatccaaaa
     3481 tgtgctggga ccacaggtta aattgattga tagtggggca gagtgtgtgc gtgatatttc
     3541 tgttctttta aattattttg agattaatgg cagtcgagat gatgaacata ggcgtcatca
     3601 tttttacact acagccggct cagacagctt tcaagcaatt gcctcagcct ggctaaatca
     3661 aacgatagat gtggagcatg tgaccttatg agtgataaca tttatgaata caaggataaa
     3721 gacaattggt ttattggcaa gatgacaggc cataatttaa tggctggctg gggggttaac
     3781 catgagctta ttgccaaaat agacgatatg ttaggtgcga ttgctggtga tgtggattgg
     3841 gaaagtccgg tcggttatga tgtgactgtt attcgttacg cctccccttt tgccttgatt
     3901 agctttgttg ttggcatgat caatcagaaa gccaatcgag cccttaaggt tgttcggcac
     3961 tcaggtgcga ttttagtgac cgaaaacgag cgattgcttg ctgtgcatat gccagatgat
     4021 ggcgtccctg tggctgactt ctttggtcaa caggcagatg gctttgggga tacgattttg
     4081 attgcgactc gaaatgaagg caagaccaag gaatttcgcc ggctttttgg tgatatggga
     4141 tatcgcgttg aaaatctcaa tgattaccca gagcttccag atgtggcaga aaccggggtc
     4201 acctttgagg aaaatgcccg cctaaaagca gaaaccattt caaggcttac tggaaagatg
     4261 gttctggcag atgattcagg gctcaaggtg gatattttag gtggcttacc tggggtctgg
     4321 tcagctcgtt tttcgggccc tgatgctact gatgagacta ataatgctaa gctattgcat
     4381 gagctggcaa tggtatttga tcaaaaggat cgctctgctc aatttcatac gaccttggtg
     4441 gttgctgcac ctggtaaaga cagcttggtt gtcgaggctg attggcatgg ctatattgca
     4501 accaagccaa aaggcgagca tggctttggc tatgatccct tgtttatcgt tggggagact
     4561 ggacgtcatg cagcagagct agctgctgat gaaaaaaaca agctgtctca taggggacag
     4621 gcggtcaaga ggttaatgga ggtatttcca gcatggcaag caaaacaatc attgtgatga
     4681 gcgattcgca tggcgatcgt gaggttgtgg cagctattaa aggccgttac cttggaaagg
     4741 ttgatgccat tttccataat ggcgattctg agctagaaag ctcagatcct atttgggagg
     4801 ggattcatgt tgtggcaggc aactgtgacc atgatagcgg ctataaggat agcctagtca
     4861 cctcctttga tggcttgact attgctcaaa cacatgggca tttgtatcat attaacttta
     4921 cttgggatag gctagattat tttgctcagg agactggagc ggatatttgt ttgtatgggc
     4981 acttgcacag acctgctgct tggcaattgg gcaagactgt ctttatcaat cctggctcgg
     5041 tcgctcagcc gcgtggtgag gtgaatgaaa agctgtacgc gcgtgttgaa tggacagcag
     5101 cttgcattag ggtggattac tttacctgtc agcataagtc ttacccatca ctttctaagg
     5161 aatttaaacg atgatagcaa aagaatttga agccttttta atcagtcatt tggatagcta
     5221 cctgattcca gcagaggagc tagccatttt tatcaacacg cataatgctg atcatgtcat
     5281 gctcttattg gttagcaatg gtttttcacg agttcctgtc attaccaagg aaaagcaata
     5341 tgtcggaacg atcagcattt ctgatataat gacctatcaa gccaaaaggc agctaacaga
     5401 ctgggagatg acgcaaacta atattggcga catggtcaat acaaagattg agaccatcaa
     5461 tattacctct agcttgactg aaatcatgca taaattggtt gattttccct ttttaccagt
     5521 tgttaatgat gacaatcgat ttatcggtat tattacgcgt aagtccattt tgaaggcggt
     5581 taatagcctt ttgcatgact tcactgatga atacacaatc acaaaaaaat gatagcattt
     5641 attgaaccct ttctagcaag caaatctctt gctaataaca gccagcaatc ctatcgctat
     5701 gatttaaggc agttttgcca gcaggtcgga cagcgtatta atcctgaaac cctagccctc
     5761 tatcagcaaa gcttgtctgg ccttacggta gcagctaaaa agcgcaagct ttcaacggtc
     5821 aatcagtttt tgtactattt gtaccagcag aaggctttga cagactattt taaaatggac
     5881 gataggatag aagcctcttt ttctttgaag ccccagctga caaggcttga caccagcgct
     5941 ttttatgctg aaacagcctt cctaaaaggg cagctcattg cgctgctgat tctggagctg
     6001 ggcttgacgc caagtgagat agcagggctt cgtcttgctg attttgacct gggtcttcag
     6061 gtgctaaggt tgcaatctca cagaggcatt cgtgtgatga ccttatcaaa ggccttgctg
     6121 ccatttttgg aaaaggcaac agaagctcag cagctctacc tctttgatca tgacgccaag
     6181 cccttttcaa ggcaatggtt ttttaaccag ctcagagatt ttttagagag cattggctgt
     6241 gcggagcttt cagcccagag tctgagagag caattcattt taaatgaaaa agcagccggt
     6301 aaatccatca ttgaggtggc tcagctgctg gggctaaaaa gcccgatcac cttagaaaaa
     6361 tattataaga tgtaatggat ataaaagtaa aagattttga aggtcctctt gatttactct
     6421 tgcacctagt gtcaaagtat gaggttgatg tttaccaggt gcctattgtg gaggtcattg
     6481 aacaatactt ggcctatatt gagaccctgc aggcgatgcg cttggagctt gctggagagt
     6541 acatgctgat ggctagtcag ctgatgctca tcaaaagcag acgactgctg ccaaagctgg
     6601 tagacaagga gcctgatgag gaggatcttg agcaagagct tttgggtaag attgaagaat
     6661 atagtcgttt caaggctctg agtcaggagt tggccagcca gcatgacaag agggctctgc
     6721 ttttttccaa gccaaagcag gagcttatct ttgagcaggc cgtcctacaa aaggataaaa
     6781 cagtcatgga tttgttttta gctttttcac agttaatggc tgcaaagcaa gaggccttta
     6841 aatataacca tacggttatt gagcgagatg attatcgtat tgaggatatg atggagctta
     6901 ttgaagctag gcttgagcta gagcaggagc ttactttgac ggatttattg aagcattgtg
     6961 atcatctcaa tgaggccatt accttgtttt tagcaagcct agaattaatc aaacggcagc
     7021 ttgttggtat tgagcagaca tcacattttg gccagattgt tttgcgaaag gagatccaat
     7081 gacctattta tctcagctgg aggccttgct gtttgtcgca ggagaagaag gactaagcct
     7141 acgtcagttg gccagcctat tagagttaac accgacagcc ttacagcagc agctcgacaa
     7201 gctttctcag aaatacaaag aggataagga atctggcctg tgcttgattg agtcctctag
     7261 gacctataag ttagtcacca aagagtgtct ggctcccttg cttaaagact atgctaaggc
     7321 tccaatcaac caaaccttgt cacgagcaag cctggaggtt ttgtcaattg ttgcctataa
     7381 gcagccgatt actcggattg aaattgacga gattcgtggt gtcaattcaa gtggtgccct
     7441 tagtaaatta gtggcctttg gtttggttca agaggctggc aaaaaggaag tgattggtcg
     7501 accaaatctt tatgcaacaa cagattactt tcttgattat atgggtatca atcatttaga
     7561 agagctggtt gatatttctt ctattgctgt tgaagagcaa gagacaaccc tgttttaaag
     7621 gcaaagagga gcttgtctca tttgcagata ggccttatgc cctctactag aagagataac
     7681 agtcctaaca aggtatagtg cctgaaaatc ctattgtcgt tatggacagc ggtcttttta
     7741 ggcatgctat taataagagt agacctgttt aagctagtga gcttttaccc ataggagagt
     7801 gactggtctg ttggagctat catcagattt cctaataaga aagagagaag gataatgaga
     7861 attaacaaat acatcgccca tgcaggcctt gctagccgtc gtaaggctga agagctgatc
     7921 aagcgagggc tggtgaccct aaatggtcag gtgataacag atttagcaac tactgttaaa
     7981 tcaggcgacc ttgttgaggt agaggggatt cctatttaca atgaagagaa ggtttattat
     8041 ctcctcaaca agcctcgtgg tgtcatctca agcgtttcag atgataaggg gcgtcagaca
     8101 gtgattgatt tgctgccgca ggttaaggag cgcatttacc ctgttggtcg cttggactgg
     8161 gatacctctg gcttattaat tttgaccaat gatggtgatt ttacagataa aatgattcac
     8221 ccccgtaatg aaatcgacaa ggtttatctg gctcgtgtca agggagtggt aactaaagaa
     8281 agcctgcgtc ccttaacacg tggtgtcgtt attgatggta aaaaaacaaa gccggctcgt
     8341 taccgcatta ttcgtgttga gcctgataaa aatcgctcta ttgttgaact aaccattcat
     8401 gagggccgtc atcatcaggt caagaaaatg tttgaagtgg ttggacactt ggttgataag
     8461 ctatcaagga cacagtttgg cagccttgat gtcagaggcc taaagcccgg agaagccaga
     8521 aggctgagca aaaaagaagt cagccagcta catcatttag cgagcacacg aaaatgatca
     8581 aagccctact cattgctcct gtcagagcct atcagaaata tatttctccc ttatttcctc
     8641 cttcctgtcg ttatcagccg acctgctcgg cctatatgat tacagctatt gaaaagcatg
     8701 gtgctaaggg tgttttgatg ggacttacca gactattaag gtgccaccct tttgccgctg
     8761 gcggagaaga cccggttcca gatacctttt ccttaaaaag acatttcata acgcatgaaa
     8821 aaatacagga ttttgaccaa aaaactgatt gacaatagca gttaaagtgc tataatagca
     8881 gttaagtatt cgttggttta aatcaaacct gttatgattt aagttagcga gtcaccgtca
     8941 accacattgt ttgctgagca tgactccggg cagtgtggtt tttttgatga aaagagtaag
     9001 cgggacaagc atgaaacaag aaatcattaa tagacaatat agggaaaaag atagtcaaaa
     9061 ccatgtggtg ctctttcagc cacaaattcc acaaaacaca ggaaatattg ctaggacctg
     9121 tgctgccacc aacacgcctt tacatatcat caggcctatg ggctttccga ttgatgaccg
     9181 taagatgaaa agagcggggc tagattattg ggataagcta gacattagat tttatgatca
     9241 tctagatgaa tttttagcac aatgtgatgg gagcttgcat gtgattagca aatttgctga
     9301 tagggtatac tcagatgaag cctacaatga tcgtcagtct cattattttt tgtttgggcg
     9361 tgaggatact ggtctgcctg agccctttat gcgtcaatat gctgataggg cactcaggat
     9421 tcctatgaat gatgagcatg tcagaagtct caatgtctct aatgctgttt gcatgatcgt
     9481 ctatgaggca cttagacagc aagcctttaa gggcttagag cttagccata cctatgagca
     9541 tgacaaacta aaatcataat aagcatatcg caaaacatca gttagattga agaagtatcc
     9601 gtaggggagc ttcttcagtc tttttttatt gtattctttg cttattaacc aagcagttga
     9661 cacgaaaatt ccaatagatc gtttaaagcc aataaaacca ttattaggct tgcattacag
     9721 gcaggtatca aagaaagata tagaaaaata taccagaaaa a
//
LOCUS       DARYUW010000067         9458 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYUW010000067 DARYUW010000000
VERSION     DARYUW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9458
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..484
                     /gene="glmU"
                     /locus_tag="TVW11_001702"
     CDS             <1..484
                     /gene="glmU"
                     /locus_tag="TVW11_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1365780.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAK
                     "
     gene            515..1069
                     /locus_tag="TVW11_001703"
     CDS             515..1069
                     /locus_tag="TVW11_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1365781.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            1069..1317
                     /locus_tag="TVW11_001704"
     CDS             1069..1317
                     /locus_tag="TVW11_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365782.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            1341..2042
                     /locus_tag="TVW11_001705"
     CDS             1341..2042
                     /locus_tag="TVW11_001705"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1365783.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(2098..2745)
                     /locus_tag="TVW11_001706"
     CDS             complement(2098..2745)
                     /locus_tag="TVW11_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1365784.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            2891..3823
                     /locus_tag="TVW11_001707"
     CDS             2891..3823
                     /locus_tag="TVW11_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1365785.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            3883..4608
                     /locus_tag="TVW11_001708"
     CDS             3883..4608
                     /locus_tag="TVW11_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1365786.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            4609..5442
                     /locus_tag="TVW11_001709"
     CDS             4609..5442
                     /locus_tag="TVW11_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1365787.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(5598..6404)
                     /locus_tag="TVW11_001710"
     CDS             complement(5598..6404)
                     /locus_tag="TVW11_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1365788.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(6491..6664)
                     /locus_tag="TVW11_001711"
     CDS             complement(6491..6664)
                     /locus_tag="TVW11_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365789.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            6784..9183
                     /locus_tag="TVW11_001712"
     CDS             6784..9183
                     /locus_tag="TVW11_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1365790.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
BASE COUNT         2618 a         1798 c         2211 g         2831 t
ORIGIN      
        1 ttcgaggctt ggtgagggcg tagtggtgag ccagtcagtg attgaggatt cagtcctagc
       61 agatggtgtg acagtagggc cctatgcgca cattcgccca gactcccagc tcgatgagag
      121 cgttcatatt gggaactttg tagaggttaa ggggtctcat ctaggggcca ataccaaggc
      181 agggcatttg acttacctgg ggaatgccga gattggctca gaggttaata ttggtgcagg
      241 aagcattacg gttaattatg atggtcaacg gaaataccag acagtgattg gcgatcacgc
      301 ttttattggg agtcattcga ctttgatagc tccagtagag gttggggaga atgctttaac
      361 agccgcaggg tctacgatag cccagtcagt gccggcagac agtgtggcta tagggcgcag
      421 ccgtcaggtg gtgaaggagg gctatgccaa gaggctgcca catcacccaa atcaagcaaa
      481 gtaaaatgat ggagagaaag caaggagatc agacatggat tttgaagaaa aaacgattaa
      541 aaggcaagag atttttgatg gtcacatttt caaagttgcg gtagatgatg tccaattgcc
      601 aaacggccta ggtcaggcta agcgcgaatt gatttttcat cgcggtgcag tcgctatatt
      661 ggctgtaacg ccagagcgta agctgttaat tgtcaagcag taccgtaagg ctatcgaagc
      721 gatttcttat gaaattcctg ctggaaaact agaggtcggt gaggccaact cagcattaga
      781 agcagcagca cgagagctgg aggaagaaac cgcctattct ggtgatttgc gtcttattca
      841 cgagttttat acagcgattg gtttttgtaa tgaaaaaatt aagctgtact tggcgacaga
      901 cctgcagaga gttgccaatc ctagaccaca ggacgcagat gaggtgattg agcttcttga
      961 gctgagctat caagaatgta tggatctagt ggcacaagga aagcttgtcg atgctaaaac
     1021 catcattgcc ctgcaatatt acgcccttca ttttggaggt gatgtgtaat gggcaagccc
     1081 ttgctgactg atgacattat cgaaaaggct cagcgcggag aacagtttga gcctgacgat
     1141 tatgcagatt ttgaaaccaa aatcatgacc tttgaggata agcatactga tcgtatttac
     1201 aaaagtcgca gaattgaaaa tgcaaagcgc agtcgctttc aatcgcggtt aaatctgatt
     1261 ctcttagcgg tgcttgtctt gattgctctc ttggtttatg cggtctttaa tttatagaaa
     1321 aaaacaaata aggatatcat atgaaaattg gaattattgc ggctatggaa gaggagctgc
     1381 ggtttttatt ggagcagctc cacgatagtc aagagcatca ggtgctttcc aatacctact
     1441 atacaggtcg tcttggtcgc catgagctcg tcttagtcca atctggtgtt ggaaaggtca
     1501 tgtcagcgat gacagttgcg atgctagcag agcattttca ggctgacgct attataaata
     1561 caggatcggc tggagcaata gctagtggct tggctattgg tgatgttgtt gttgctgatc
     1621 gcttggtgta tcatgatgtg gacgtgacgg cctttggcta tgactatggt caaatggctg
     1681 cgcagcccct ttactttgac agtgatagca agctggttga gacctttaag caggtgcttg
     1741 atcaggaaaa gaccaatagt cggattggcc tgattgcaac aggagatagc tttattgccg
     1801 gccaagacag tattgatacc attaaagcac atttcccaga gaccttagca gtggaaatgg
     1861 agggagcagc agtggcacag gcagctcaag ctgctggcaa gccatttatt gttgttaggg
     1921 cgatgagtga cacagcggcc cacgatgcta atatgacctt cgatcagttt attgttgagg
     1981 ctggaaaaaa atcagccaag gtcttgatag cctttttaga ggccttacct gataaaaaat
     2041 gatgaccaaa aaaacctgat agcctgtggt gacagcaaat atcaggtctt tttttattta
     2101 aatagcagta acaaagagct gcttggcgat gttttcagga atgatcaatt ccttatctgc
     2161 ataagtgatg gtataggttt ttgcgaagtc atctatttga atcagtctaa actcactatt
     2221 gatcgtcagc tggtgtgctt ctaggtactg gataagctca aagtgatcat gcaccctgct
     2281 caaacgaaaa attcccagct ctttaatagt attaagcgtt gttttgttga tttcgattag
     2341 tggctgctgg cggcgtggaa ttgtccctcc atgagggcaa aaagtaggat agccaagggt
     2401 tttatccaag cgatcaataa acatatctga cacagtatgc tctagtacct cagcctcttg
     2461 gtgcacctct ctagcagtat agcccagttg atggatcaag aaaacctcca tcaatcggtg
     2521 cttacgataa agatttgcca ctaagcgctg cccttgctct gttagataat agccgcaggt
     2581 cttatccttt acaatccagc cttgtgcgat cattttctta atcatttctg acacagcggg
     2641 tgcagaaacc ttcattctct ctgcaaccat tttgttagaa attttaatgt tttgctctcc
     2701 gatttcataa atacatttca aatagtcttc tttattaggc gtcatgtcta aaagcctttc
     2761 tcttatttat aatgattatt atatcagatt atttcataaa aatcttgaca aaggcctaaa
     2821 aaaaagttat gctaatagca taattaacta tacttaatta attaaataat agatcctaag
     2881 gagataactg atgaaaaaga aacttagcct cgccttgagt gcttttttgg ctgttttcat
     2941 gctggttgcc tgctctaatg gtggaaacaa ggaagctaag agtgacaagc tcaaggttgt
     3001 ggttaccaat tccattattg ctgacatgac taaaaatatt gcaggtgaca agattgactt
     3061 gcacagcatt gtgccgattg gtcaagatcc gcatgagtat gagccattgc cagaagacgt
     3121 tgagaagacc agcaatgccg atcttattct ctataacggt attaaccttg aagacggcgg
     3181 acaggcttgg tttacaaagc ttgtaaaaaa tgctaagaag gaaaaggaca aggactactt
     3241 cgctgtatct gatggtattg atgtgattta cctagaaggt gaaagtgaaa aaggcaagga
     3301 agaccctcat gcttggttga atcttgaaaa tggggttatc tattcaaaaa atattgcaaa
     3361 gcaattgatc gctaaagacc ctaaaaacaa ggaaacctat gaaaacaacc taaaagctta
     3421 cgttgagaag ctagagaagc ttgataagga agcaaaatca aaatttgatg ctattgctga
     3481 caataaaaag ctaatcgtca caagtgaagg ctgcttcaaa tacttctcaa aagcttacgg
     3541 tgtcccatca gcctacatct gggaaatcaa cactgaagaa gaaggaactc cggatcaaat
     3601 ttcatcattg atcgaaaaat tgaaagacgt taagccatca gcgctttttg ttgagtcaag
     3661 tgttgacaga cgtccaatgg agactgtttc taaggacagt ggtattccga tctatgcaga
     3721 aatctttact gactctgtag ccaaaaaagg ccaagatgga gacagctact atgccatgat
     3781 gaaatggaac cttgataaaa tttctgaagg cttagcaaaa taatataaca ataaagcaca
     3841 gcagcttctg gtgttgtgct ttgtttgtat taaggagaaa aaatgattga tacgcaaaat
     3901 ctttcggtta gctataacgg taacgtaaaa gccttagaca atatctcact acaaatcaaa
     3961 ggaccagcta tcgttgggat tatcgggcca aatggtgcag gaaaatcaac cttgatgaag
     4021 gctatgctca atcttttaga ttatagtggc caagtaactg ttgatcaaaa ggacggtcga
     4081 aggctggggc atacgattgc ttatgtagag cagcgcagca tgattgacta caactttcca
     4141 attacggtga aggagtgcgt ctcattaggg acctacacta ggctagggct ttttcgtcgt
     4201 gtcggaaaaa aagaatatga tcaggttgac cagctgctag agcaggttgg gcttgctggc
     4261 tttggtaatc gtccgataaa atctctttct ggtggtcagt ttcagcgtat gctagtagct
     4321 agatgcttga ttcaggagtc agactatatt tttcttgatg agccctttgt tgggattgat
     4381 tcggttagtg aaaaaatcat cattgacctg ctcaaggact tgaaaaaagc aggcaaaacg
     4441 attttaattg ttcatcacga tttaagcaag gtagagcatt actttgatga gttagtggta
     4501 ttgaacaaag agctgatcgc ttatggatct gttgatgagg tgttcactgt tgaaacccta
     4561 tcaaaggcct atggtgatca tctattctta ggaaagggaa tgttttaaat gtatttgaag
     4621 ttttttgagg gcctgatgtc ctatcatttt ttacaaaatg cccttattac agccgttgtt
     4681 attggtattg tatcaggagc agtaggctgc tttattatcc ttaggtccat gtcattaatg
     4741 ggtgatgcga tttctcacgc tgttttgcca ggagtagcct tgtcctttat tttagggatt
     4801 aatttttttg taggggctat tgtctttggc ttgctagcct ctgttatcat tacctacatc
     4861 aaggaaaact ctgttatcaa gggagacaca gcaataggga taacctttag ctcttttctt
     4921 gccttagggg ttattctgat tgggattgct aatagctcaa cggatctttt tcatatcctc
     4981 tttggaaata tcctagcagt gcaagacagt gacaaatgga ttacgatcat tgtttcggtt
     5041 tttgttttgg ctattattgt cctcttcttt aaggaattac tcattacctc ctttgatcct
     5101 gtgctagcaa ggtctatggg aatgaaggtc actgcttatc attatctgtt gatgattttg
     5161 ttgaccttgg tttcggtgac tgctatgcaa agtgttggta ccattttgat tgtggcgatg
     5221 ctgattacgc cagcggctac agcgtatttg tatgctaaca gcctaaaggt aatgctggtt
     5281 atctcctcat gcttgggagc tatgacctct gtgttggggc tctatttggg ctacaccttt
     5341 aatattgcag caggctcaag cattgttttg acctcggctg tggtgtttct gattagcttc
     5401 tttgtttcgc ctaagcaggg ctactttaaa aagcattcct agtaaaccat agctggctgt
     5461 gaatggatag ctgctaatga tatgatcaat aggctagctt ctttatttaa ttgatagcaa
     5521 aaaatcacga ccagctcttg aatcggtggc ttttccgata aggagctggt cgttttattg
     5581 ttgttgtagc ttagaggcta ttttttaaag gagtaatcct taacaatgtc aatagcatta
     5641 atagtgatgt tctctattgg tttgtcattt gggccgactg ggctggcagc tattttatca
     5701 acgatatcca taccctcaat aacctgacca aaaacggtat agccaccatc taggctagga
     5761 ttaccccctt cttcgtagga gtcaatgatt ggcttagagt aattatcaat tgataaggcc
     5821 ttggcttggt tgagcttgct ttgattgatg aagaactggc tgccattagt atctgcaccg
     5881 gcatttgcca tagcaagagc ccctcgaatg ttatataaaa atggtgagat ttcattagca
     5941 aagccttgtc ccgcatcttt tttgctgtcc ttgcccttcc aaatggattc tccgccagat
     6001 ccatctccct ttggatcacc ggtttgaatc ataaagttat taatcacccg atggaacaaa
     6061 agtttgtcgt aatagccttc cttggcgtgt gttaaaaagt tttcaacagc aagcggtgca
     6121 tacttgggga agagcttgag ggtgatatcg ccctgattag ttttgataat gaccttagct
     6181 tcgtctttgt cgacttcttt atttaattgt ggaaactgat cagcgtcagc cttgagtgct
     6241 tttttgattt ttgcttcata agcctttgct gctgtctcgc tttcctctct agcgattttt
     6301 tcatcgacgt attcatcacc tttaatagca cgatcaatgg actcacagcc acttaagcta
     6361 agcaaagcaa gaccgattaa gccaaaagat agtagttttt tcatgtgtac tccttagaac
     6421 aatttctttt attttaacat aaaatgactt ggaaaataaa gctaaagggc attgagacga
     6481 agtctatttt ttaactattt ctaagcttct ctaagtcctc ctgagaaacc ttgaaggtga
     6541 cttgcccggt ctgcatatca acgatagcct tgacttcaac tcctttggga attagcttgc
     6601 catgccccat atcaatttgc aggggaagct taccataggt caaggtgtta aattcttttt
     6661 ccatcttcaa ctcctatttg ttcttatgat tgacattata gcataaaatc aagcagcttc
     6721 atctatttat tgagaatttt aatgtcatct ttcataacga ttaaaaaatg ttataataag
     6781 gctatggcta gaagaactca acgacaaaaa aatcccccta agagacgttt aacaaaggca
     6841 gagcttgaaa agcaaaaggc tattaagaga atgattgctt ctttctcctg cgctttattg
     6901 cttgtttttg ccatgcttcg cttaggtgcg cttggggtta ccttatataa tcttattcgc
     6961 tttatggttg gcgacttagc caatctcttg atgttggcgg tcctttttta cctctttttc
     7021 ttcaagtggc tcaggcaaaa agatggcctt atcgctggct ttatcatctt gtttttaggg
     7081 cttctggttg aatggcatgc ctatcttttc tcattgcctc agctagctca tcaggctatt
     7141 gttgctggga ctatccagct aatcaccaat gacctgctag cctttaaggt tagcgagttt
     7201 gttggtggtg gtatgcttgg ggccatgctg tacaagccta tttccttctt gttttctaat
     7261 attggctctt attttattgg ttttttgttt atcctgctgg gcttgttttt aatgacccct
     7321 tgggatattt atgacgtcag tcattttgtt aagacgcttt ttgaaaagct atccctggcc
     7381 tatcaagaaa acaaggaaaa gcggtttgtt gagcgagaaa agcaacgatt gctggctgaa
     7441 gaggagcgtc tagcaagaga ggccttggag gagcaagaat atctggccaa tcaagcgatt
     7501 aatcctgaga caggtgagct tttagcagag ccagaagacc tattgatgga gatggctgat
     7561 cagaaggagt ctgaagcatt ttttgagccg gaaattctgg cctatgactc acaccctgct
     7621 gatgatgagc ctgaggcatt tggagatgaa gaggagtctg taccagaagc ccctctaacg
     7681 ggtgcttcag caatcgcagg agaggcgccg ctgtcagatg atgaggagct gtcagtggag
     7741 gtcgatttca cgccaaagac caatctgctt tacaagctgc cgacgataga gctgtttgct
     7801 gctgataagc ctaaaaatca attcaaggaa aagtaccttg ttcgtcaaaa tatcaaggta
     7861 ttagaggata ccttcagaag ctttggaatt gacgtcaagg tggagcgggc agagattggg
     7921 ccatctgtaa ctaaatacga ggttaagccg gctgttggtg ttcgtgtgaa tcgcatttcc
     7981 aatttagctg atgacttggc cttggccttg gcagccaagg acgtacggat tgaagctccg
     8041 atccctggca aatcccttgt gggtatagag gtaccaaatt cagaggttgc aacggtttct
     8101 ttccgcgagc tttgggagca atccaacaca tctgatgaca aattattgga aattcctctt
     8161 ggtaaggctg tcaacggtag tgccagaagc tttgatttga cccgcatgcc tcatttgctg
     8221 gtggctggct caacaggatc agggaaatct gttgcagtca acggtattat ctccagtatt
     8281 ttaatgaagg ctagaccgga tcaggtcaaa ttcctaatgg tcgatccgaa aatggttgag
     8341 ctgtctgttt ataatgacat tcctcacctg ttaatcccgg tggtcaccaa ccctcgtaaa
     8401 gcaagcaaag cgcttcagaa ggttgttgat gagatggaaa atcgctatga gctgttcagt
     8461 aaggtcggtg tccgaaatat tgcaggctac aatgccaagg ttgaagccta caacaagcaa
     8521 tctgagcaaa agcaaatccc tttgccgatg attgttgtta ttgttgatga gctagctgat
     8581 ttgatgatgg tggctagtaa ggaggttgag gatgctatta ttcgtcttgg gcaaaaggcg
     8641 cgtgcagcag gtatccatat gattttagct actcagagac cttctgttga tgttatttct
     8701 ggattgatta aggctaatgt tccatcacgt attgcctttg cggtttcatc aggaacagat
     8761 agtcgcacca ttcttgatga aaatggcgct gaaaagctgc ttggtcgcgg ggacatgctc
     8821 tttaagccga ttgatgagaa tcaccctgtg cgtctgcaag gctcctttat ttcagatgat
     8881 gatgttgagc gcattgttag ctttatcaag gagcaggcag aggctgatta tgatgattat
     8941 tttgatccgg gtgaggttag tgactctgat tatggcagca gcggagctcc tgagggtgat
     9001 cccctttttg aggaagcaaa ggctcttgta ttggaaacgc aaaaggcaag cgcctcgatg
     9061 ctccaaaggc gtctatcggt tggctttaac cgagcaactc gactaatgga cgaattagaa
     9121 gaggccggtg tcattggtcc agctgagggg actaagccaa gaaaggtact gcaaaccaat
     9181 taaaaaagag ctcatctaaa ggctcatcat aaaacaaacc cgtaccaagc taagcttaac
     9241 catgtggctt gatacgggtt tttgatatgc tgctttgaaa aagtcccact caagcagaaa
     9301 actcaaagac agcttcattt tgagtgatag tgctagagct aattggcaga tctaatctgc
     9361 taagtcaata tgtccataat accttaatat atagagagtt ttaaaaaaag attagctaat
     9421 atcacatatt taagaaagtt ttctgatata ctaatgct
//
LOCUS       DARYUW010000068         9337 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYUW010000068 DARYUW010000000
VERSION     DARYUW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9337
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            25..261
                     /locus_tag="TVW11_001713"
     CDS             25..261
                     /locus_tag="TVW11_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1365791.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            325..1596
                     /gene="murA"
                     /locus_tag="TVW11_001714"
     CDS             325..1596
                     /gene="murA"
                     /locus_tag="TVW11_001714"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1365792.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1600..1788
                     /locus_tag="TVW11_001715"
     CDS             1600..1788
                     /locus_tag="TVW11_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1365793.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1820..2698
                     /locus_tag="TVW11_001716"
     CDS             1820..2698
                     /locus_tag="TVW11_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1365794.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2712..2870
                     /locus_tag="TVW11_001717"
     CDS             2712..2870
                     /locus_tag="TVW11_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365795.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3610..4653
                     /gene="pheS"
                     /locus_tag="TVW11_001718"
     CDS             3610..4653
                     /gene="pheS"
                     /locus_tag="TVW11_001718"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1365796.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4843..7248
                     /locus_tag="TVW11_001719"
     CDS             4843..7248
                     /locus_tag="TVW11_001719"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1365797.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVETVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7483..8559
                     /locus_tag="TVW11_001720"
     CDS             7483..8559
                     /locus_tag="TVW11_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365798.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8569..9273
                     /locus_tag="TVW11_001721"
     CDS             8569..9273
                     /locus_tag="TVW11_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365799.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
BASE COUNT         2647 a         1963 c         2213 g         2514 t
ORIGIN      
        1 ttagactttt gatataataa agctatggaa gtaattagaa ctcttttaat gtttttcagc
       61 catttattat ttattggcat tagttatcag ctactcatta gcctagttga ttggtcaaaa
      121 ttcattcatt accgaccaga gaatatggga aggcttcgct tgcttgtcct ttttttggca
      181 attgcctcag gctatttagt tagtcgcttt atgctggaat taattcaaat cagtcagtat
      241 ctgctgtatg atttccacta gagtaggcag tcaggaagta tgatataata ttagtacgat
      301 gaccagtagg aaatggagaa gcttgtggat aaaataatca tagaaggtgg gagcacacgt
      361 ttagagggag aggtaacgat cgaaggcgct aaaaatgccg ttcttccttt actagcagct
      421 actatcctcc cctcaactgg aaagactgtc ttgagaaatg tgccgattct ctcagatgtt
      481 tttacgatga actatgttgt gcgtggccta aatattgacg tcgactttga tgaggctgcc
      541 aaccagatta cagttgatgc ctcaggggac attttagatg ttgccccgta cgagtatgtc
      601 agccaaatgc gcgcctcaat tgtggtttta ggcccgattt tagctcgtaa tggccatgcc
      661 aaggtatcga tgcctggagg ctgtacgatt ggcagtaggc cgatcgattt gcatttaaag
      721 ggcctagagg ctatgggcgc tgagatcacc cagcagggtg gtgacatcac tgcaaaggct
      781 gagcgcctaa agggggcaat gatctatatg gatttcccat cagtgggggc tacgcaaaat
      841 ttgatgatgg cagcgaccct tgctgatggt gtgacagtca ttgagaatgc tgctcgcgag
      901 cctgagattg ttgacctagc ccagctgctc aacaaaatgg gggctaaggt tcgtggggca
      961 ggtaccgaaa ccctgaccat aacgggtgtc accagtctat gtggggttga gcatgatgtt
     1021 gttcaggatc gtatcgaagc aggtaccttt atgattgctg cagcaatgac ctccggtaat
     1081 gtgctgatta gagatgctgt atgggagcat aatcggccct tgatttctaa gctcatggaa
     1141 atgggagtgt ctgttgtcga agaggatgca ggcattaggg tgcaggctga tgtgactaaa
     1201 ctaaggcctg tcactgttaa aactcttcct cacccaggct ttccaacaga tatgcaggct
     1261 cagtttacag cccttatggc cattgttaag ggagaatcta cgatggtgga aacagtcttt
     1321 gaaaatcgtt tccagcacct agaagaaatg cgacgcatgg gcttacaatc tgaggtattg
     1381 cgtgatacag ctatgattca tggtggtcac gaattacagg gagcgcctgt gatgtcaaca
     1441 gacctgcgag ctagtgcagc cctcatctta acgggaatgg ttgccaaagg caggaccact
     1501 gtgaataaat tgaaccattt agatcgtggc tattatcagt ttcatgaaaa gcttgccaag
     1561 ctaggtgcca acattcagcg aattagtgag gagtagtcaa tgactaatgg ttggagatat
     1621 gtcataaatc agctaatgct aatcatagct attggactgc tcggactctt ttgtctggcg
     1681 ctgggactaa tgattggcta tagccttatc ggtgatggcc aaaatccttt agcgatttta
     1741 tcgccagata agtgggctga gctgattcat aaatttacgg gaaagtaggc atggcctgct
     1801 ttttatgata agaggaaaga tgatcaaaaa gaagaaagac atcaggctgc ttaatgcctt
     1861 tttagcgctc ttgcttgttc ttggaacagg ttatttggca ggacatgatg acctagcagc
     1921 tgataacccg atcaagcagg tctaccaaag gattcttggc tctgacacgc agcaagccgg
     1981 gctaccaaag gcaagccgag actgggacac tccctccaag gccttggcag attcggtcat
     2041 gacagccacc atcaaacagc aattaggtga tgtgattact tggaatggca ctggtgccta
     2101 tatcattaac cataataaaa cgacgctaaa tgcaaaggta gctagtctcc cctatgccaa
     2161 taataaaaca aagatggtac aagggcaaag cgttcctacc gtagccaatg ccctgctaac
     2221 caagtcaacc cgacaatatc agaagcgcaa tgacactgga aatggctata gctcatggaa
     2281 gcctgctggc tggcatcagg ttcaggggtt aaagggaagg tatagtcacg cagtggatag
     2341 agggcatctt ctaggctatg cgcttgttgg cgggctaaaa ggctttgatg cctcaatggc
     2401 taatcctagt aatatcgcta ctcaaaccgc atgggctaac caagcagcta acgagagatc
     2461 aaccggacaa aactattatg aaacaaaaat tcgcaaagcc ctagatagca ataagcgtgt
     2521 ccgctatcgt gtaactttgc tttatgaggg aaataatctc ttagcaagcg gcagtcatct
     2581 tgaggcaaag tcatcagatg gtagcttaga atttaacgtc tttatcccta atgtacaggc
     2641 tggattacag attgattatc aaacaggtca gatcactgta gcttcttccc agccttagtg
     2701 aggcacatca catggcaaaa gctgatcacg tagctagcca tcatggcaga gaagcattag
     2761 tccttgtagt ccctcaaaga aaggtgctaa caatatttgg tcttgtggct ttagtagaaa
     2821 aacagatagg tcctttagtc gaagcaccaa gcatgccagc tcctgattag gacaaatgtc
     2881 aaggctaagc ggtggtaagt taaagtctca caaaagacaa gactggactt ttggctatag
     2941 tcctttatga ctgatgccag ctgataatgg ctcaagatga ttgaggtttc tagcaatgct
     3001 tgtggctagc ctatcgtctt agttagcgct gattgatgag atgttgaaca gttcttgact
     3061 aaaagcatcc ctacccttac gcctacgtcc tggttagtga agaaataagc attgtcataa
     3121 aggcattttt ttgatacaat aaaagtaatt gaatagcagt ctatgagact agtactaata
     3181 gggaagttaa tagggaatgg gggtcgtgac tggaagcctt cttaatgaaa cgattaggaa
     3241 ttcactcaat caaggacgag gtaattaagg tctgacttgc tcagatgaaa acggatggta
     3301 ccgcgtgtca acgctccgct ttagatagga gccttgatac gccttttttg atgacgtgct
     3361 gttactatta gctatttaat cacaagcaag cactagccag ccaaaagtaa gtgatcacta
     3421 taagcataga aagataggag ctgtagctta tctagaaaag caagggtgat cagtcgtccg
     3481 cccaaaagtc tttcttagct tttgtgatgt gactagctga cctagctgct cacagcttag
     3541 cctaaaaggc ctattagcac aaggactgcc agcattaatg caatcatttt ccaaacagaa
     3601 gggaatatca tggatttaca agcacaatta gaagaactga aaaccaagac acaagaagcg
     3661 ctcaagcagc taaatggtga ccacagcaag gaattacagg agctgcgggt tgctgtcctt
     3721 gggaaaaaag gaacgcttac cgaactgctc aagggactaa aggatctctc aaatgacctg
     3781 cgtcctgttg ttggcaaaca ggtcaatgag cttcgtgact ttttgaccca agcctttgaa
     3841 gagcaggcta aggtggttga ggcagcaaag attcaggcca agctagattc tgaaagcatt
     3901 gatgtgactt tgccaggccg tcagatgaag cagggctatc gacatgtgct cactcaaatc
     3961 agtgaagaaa ttgaggacat tttcttgggc atgggctttc aaattgttga tggctttgag
     4021 gttgaaaagg attattataa ttttgaacgc atgaaccttc caaaggatca tccggctcgt
     4081 gatatgcaag acaccttcta tatcacagag gatattttgc tgcgcaccca caccagtcct
     4141 gtacaggcac gaacactgga ccagcatgat ttttcaaagg ggcctctcaa gatgatttca
     4201 cctggacgtg ttttccgtcg tgacaccgat gatgccactc attctcatca atttcaccaa
     4261 attgaaggct tagtcgttgg taagtctatt tctatgggag acttgaaggg gactcttgag
     4321 atgatcatta aaaagatgtt tggtaaggag cgtaagattc gcctgcgccc atcctatttc
     4381 ccttttactg agccatctgt tgaggttgat gtctcatgct tcaaatgtgg tggtaaaggc
     4441 tgcaatgtct gcaaaaaaac aggctggatt gaaattcttg gagctggtat ggtgcaccca
     4501 agcgttttag aaatgtcagg tgtgaatgcg caggagtatt caggctttgc ctttgggctt
     4561 ggtcaagagc gcatcgccat gctgcgctat ggtatcaacg atattcgagg cttctaccaa
     4621 ggagatagtc gcttttctaa gcagtttaag taatagtgat catatggtca aaaaccaaat
     4681 catcagtttg aaaaaagaac tgacgctcaa tctggagctg ttctttggat tagaatcaga
     4741 aaggaaaaag acgggtaaag agcaaagaag tgattggcta gcttatctca agcaggtgct
     4801 aggcagatct ctcatcagcg ctcactactc tattgaaggc ttatgttagt atcttataaa
     4861 tggttgaaaa aattagttga cattgatgtc tcaccggccg agctagctga aaaaatgtca
     4921 acaacaggta tcgaagtaga aggcatcacc agcccctctg aaggtttatc aaagctagtt
     4981 gttgggcata ttgtctcatg tgacgctgtt ccagaaacgc acctgcacct ttgtcaggtc
     5041 aacacaggag atgatgagct tcgtcaaatt gtctgcggtg cacctaatgt caaagcaggg
     5101 attaatgtga ttgttgcgct gcctggagct cgtattgcag acaattacaa gattaaaaag
     5161 ggtaaaatac gcggtatgga gtctcttggc atgatctgct cacttcagga gcttggctta
     5221 ccagatgcga ttattccaaa agatttttca gaaggtatcc agatcctacc ggaaacagca
     5281 gcagcaggtg atagcatttt cccttacctt gatttagatg acaatatcat tgagctttcc
     5341 atcacaccta atcgtgctga tgccttatca atgcgtggtg ttgcccatga ggtggcagct
     5401 atctatggca agtcagtgtc atttccagaa aagcccctta tcgaatccgc taaagcagca
     5461 gctgatagtc tagaggttgc tattgactct gacaaggtgc tgacctatgc tagtcgtatt
     5521 gttgaaactg tcaccgtcaa gccaagtccg caatggctgc aaaatcttct gatgaacgct
     5581 ggcattcgtc caatcaacaa tgttgttgat gtgaccaatt atgtcttgct gtattttggt
     5641 cagccaatgc atgcctttga ttatgatacc tttgctgatc ataagctttt agcgcgtgat
     5701 gcgcgtgagg gagaaaggct tgtcaccctt gatggagaag agcgtgtgct aaccacagat
     5761 gacattgtta ttaccgtagc agaccagcca gtggctctag ctggtattat gggaggcaaa
     5821 tcaacagaaa tcaccgcctc ctcaaagaca gtggtgcttg aagcagcagt ctttaatggc
     5881 aaatcaatcc gtaaaacaag cagtcggcta agtcttcgtt cagaaagctc atcacgcttt
     5941 gaaaaaggga ttaaccatga cacgcttgta gaggccttag attttgcggc agccatgcta
     6001 gaagagctag ccggtgggac tgttttagca gggcgcttgc aggcaggctc actgcctacc
     6061 aatccggtag aggtttcaac cagccttgat tacgtcaatg tccgcttggg aacagccttg
     6121 agctttactg atattgaggg gatttttgca aggcttggct ttggtattag cggaactgct
     6181 gaacacttta ccgtttcagt gccacgacgc cggtgggata taacaattcc ggctgaccta
     6241 gtcgaagaaa ttgcccgtat ctatggctat gatcgattgc caaccacatt accagaagct
     6301 gctggcacag ccgcagaatt aaccaaaaca caggcccttc gtcgtcagct gcgtggtctt
     6361 gcagagggac tgggtttaac agaaatcatt tcctatgctc taacaacacc tgaaaaggcc
     6421 cttgaatttg caatgaagcc aagccagtta acagagctga tgtggccaat gtcagtcgag
     6481 cgctctgtcc ttcgtcaaag catggtatca ggtatgcttg acacccttgc ctacaatgtg
     6541 gcacgtcaac agcataacct tgccgtttat gagattggta aggtctttga gcaagagggc
     6601 aatcccaagg agacattacc aacagagctt aatcactttg cctttgctat cacaggctta
     6661 gtagcagaca aggattttca gacacaagcg caagcggttg atttttacca tactaaggga
     6721 atcctagagt gtctctttga taagctagga ctgtctgtgg attatatccc aacaaaggag
     6781 atggcgagca tgcacccagg acgtaccgca cgtattcagc taggagatca agtgattggc
     6841 tttgttggtc aggtgcaccc acaggctgct aaggcttatc atatcccaga gacctatgtt
     6901 gcagagcttg acctgactgc tatagaggca gctctaccag ctcatcatgc ctttgtggaa
     6961 atcaccaaat acccagctat ggtaagggat attgccttat tggttgatgc ctcaaccagt
     7021 catcaagcca ttctttcagc gatcacgtct gccaaggtaa agcgtctaac agagattaag
     7081 ctctttgaca tttacgcagg agcaattatt gcggccggta aaaaatcaat ggcctatagc
     7141 ctgaccttcc aaaatccaac agacaatctg actgatgagg aggttgccgg ctacatggag
     7201 aaaatcacca aggccttggt agaaaaggtt ggtgcagagg tgagataagg acgcttctaa
     7261 tgactagcta cctaaaaaaa gctcatttca aaggcttagc tgcaattgtt ctgttgcggc
     7321 tgagcttttt ttgatgctta gactgtcctt atcctatgct agttgcagca agggtttaga
     7381 gatgatttta tttaaattat cagtcaaaaa tattttttct aatcaaattc ctagctttat
     7441 ctgatctcct ctgctatact gtgcaataag taaggagatt atatgttttt agccctaaat
     7501 gaaataaaac aagctaagct cagatatggc ttgattatgg gactgctctg tttagtagcc
     7561 tatttgatgt tctttttatc cggtttagcc tttggattaa tgcaggaaaa tcgctcggca
     7621 gttgacagct ggcaggcaga tacagttctt ttgtcaaagg acgctgacgc caatctcagc
     7681 ctatcctctt taaagaccag tcagcttaag gagatcaagg ctgatgaggt cactccccta
     7741 gcccagctga atacagttgc ttggtcaacc caagctccaa cagaagaaga caaagaaaaa
     7801 atcagctttt ttggcattga gagagagtcc tttctcaagc ctacaatcac aaaaggaagg
     7861 ctatttaagt cagacaaaga ggtggtgatt gatcaaagcc ttgctgagaa aggaggcttt
     7921 aagcttggag atcagctgcg ggtatcggcc tctaaccaga cctataccat cgttggctat
     7981 accaagaatg ctagctttaa cgtgtcacct gttgcttacc tcaacctgac agcctttcag
     8041 ggcttactgt atggtcaaga agcaggcgca caagacccaa atgttaatgc ctttattatc
     8101 aaaggcaagc tagctgacta tcccaaggaa gagcttcagc agctaacgat tggcgacttc
     8161 atcaacaagc tgccgggcta tagtgcacag ctcttgacct ttggctttat gattgggttt
     8221 ttagtgttaa tctcagccat tatcattggt atttttatgt atgtgctgac cattcaaaag
     8281 gcaccaatct ttggtatcat gaaggcacaa ggcattgcta atcgtaccat tgcaaatgct
     8341 gtgctatcac aaacctttgt cctaagcctt ttgggcagca gccttggcct actaggcacc
     8401 tggctaagct cgcttgtctt accagcaaca gttccctttc agagcaattg gtacctatat
     8461 gcgcttattt tagttgctat ggtagtcttt gcagtattag gcaccctctt ttcagtcttt
     8521 acgattgtta gaattgaccc tctagaggcc attggttagg agaagaatat gacagtatta
     8581 gcatttaagc aggtcacaaa gtcctttaag gacggtgatc agaccattga agccctgaaa
     8641 aagacggatt ttgcgattaa agcaggcgag tttgtcgccc ttataggtcc atcaggctca
     8701 ggcaaatcaa cctttctgac cattgcaggt ggtctacaaa caccaagctc aggacaattt
     8761 ttagtcaatg gcaaggatta caccaaccta tctgaaaagg aacgatcaaa actacgcttt
     8821 aaggacattg gctttatcct gcaggcttct aatttgattc catttttaac cgtcaaacag
     8881 cagctagaat tagttgacaa gttgaccaag cacaagcagg aagcaaagcg tcagcagctc
     8941 tttgaggact tgggaatcgc taagctggct aataagctgc cccaagattt atccggtggc
     9001 gagcgtcagc gtgttgccat tgccagagcc ctataccatg atcctgtgat cattttagca
     9061 gatgagccga ctgccagtct ggatactgaa aaggcctttg aggtcgttga acttctagct
     9121 aaagaaagca aggaaaaaaa caaggcaatt atcatggtaa cccatgataa ccgtatgatt
     9181 gactattgcg ataaggtcta tcgcatgcag gacggccaat tgagtcaaga caatcatcat
     9241 atagctagca atgccgcaat gactcaaaac taatcgaata ggaaaagctc tgctctagcg
     9301 atatagcagg gctttttagc tgctctaaat tatctca
//
LOCUS       DARYUW010000069         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYUW010000069 DARYUW010000000
VERSION     DARYUW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            101..1027
                     /locus_tag="TVW11_001722"
     CDS             101..1027
                     /locus_tag="TVW11_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1365800.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TVW11_001723"
     CDS             1135..2421
                     /locus_tag="TVW11_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1365801.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TVW11_001724"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TVW11_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TVW11_001725"
     CDS             2977..3189
                     /locus_tag="TVW11_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1365802.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TVW11_001726"
     CDS             complement(4085..4225)
                     /locus_tag="TVW11_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365803.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVW11_001727"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVW11_001727"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1365804.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TVW11_001728"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TVW11_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TVW11_001729"
     CDS             8213..9118
                     /locus_tag="TVW11_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1365805.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYUW010000070         9047 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYUW010000070 DARYUW010000000
VERSION     DARYUW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9047
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVW11_001730"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVW11_001730"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1365806.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVW11_001731"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVW11_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1365807.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVW11_001732"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVW11_001732"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1365808.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVW11_001733"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVW11_001733"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1365809.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TVW11_001734"
     CDS             complement(6925..7623)
                     /locus_tag="TVW11_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1365810.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TVW11_001735"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TVW11_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
BASE COUNT         2660 a         2148 c         1774 g         2465 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaa
//
LOCUS       DARYUW010000071         8757 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYUW010000071 DARYUW010000000
VERSION     DARYUW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8757
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            231..1355
                     /locus_tag="TVW11_001736"
     CDS             231..1355
                     /locus_tag="TVW11_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1365811.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(1517..2110)
                     /locus_tag="TVW11_001737"
                     /pseudo
     CDS             complement(1517..2110)
                     /locus_tag="TVW11_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            2179..4152
                     /locus_tag="TVW11_001738"
     CDS             2179..4152
                     /locus_tag="TVW11_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1365812.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            4176..5618
                     /locus_tag="TVW11_001739"
     CDS             4176..5618
                     /locus_tag="TVW11_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1365813.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            5699..6508
                     /locus_tag="TVW11_001740"
     CDS             5699..6508
                     /locus_tag="TVW11_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1365814.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            6820..7977
                     /locus_tag="TVW11_001741"
     CDS             6820..7977
                     /locus_tag="TVW11_001741"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1365815.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            8063..>8757
                     /locus_tag="TVW11_001742"
     CDS             8063..>8757
                     /locus_tag="TVW11_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1365816.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT         2966 a         1686 c         1872 g         2233 t
ORIGIN      
        1 tatagaaaaa taaagaaaca tgctgagagt tgatcaaaac acttactata cttacgatga
       61 caagtaactt gctaaagtaa tggttgacat ataattgtaa aaaaacagaa ataaaaaaaa
      121 aacggtttaa tattgaccta attggcaata acgtttacaa taaaggtata attatctgcc
      181 gttgataatt aggagacatc atgtctagat aaaaacaaaa ggggaataaa atggcaaaaa
      241 aagaaatgaa gttttacctt cgtaaatcag cctttgggct agcttcagta tcagcagccc
      301 tcttggttgg tgcggcagct gtatcagcag attctgttga gtcagctggg cctgtagcag
      361 ttgctgttac agatagttta gatagtgaag ccgcagctac aaaggcagaa gctgatctag
      421 ttgctgcaaa agcagaccta gcagcagcag aagtagcaat cacagctgca aaagctgaat
      481 ttgacaccgc tcaagcagac ctagctaccg ctgaagctac tatcgcagag cttgagcaaa
      541 aaattcctga gttagagaaa aaaattcaag aagctcagga aaaactaaac tatgaaaatc
      601 gaccatcacc taaacgtgtg ggcagtgatg atgaagatga cacagtagct agaaagctta
      661 tgtcagaaaa ggaagctctt aaggctgagc ttcaaaagac taaagaagcg ctagatacag
      721 ctaaaagagc ttatgctggc atcgaagaaa gaaaacaagt agcagcaact aagctagatg
      781 cagctaacaa ggcttttgct ggagttgaag aaaagcatgc tcaagcaatg gctgcatttg
      841 gagcagcatt cgcagcatac aaggaagctg ttaaggctga attgaaggca gcaggtgcta
      901 gcgacttcta caccaagaag attgactctg ccgacacagt tgacggtgtt aagacactca
      961 gagaaatgat cttagactca attgctaagc cagaggttga accagaggct aagcctgaac
     1021 ctaagccaga accaaaacct gagccaaaac ctgagccaaa accagaacct aagccagaac
     1081 caaaacctga gcctaagcca gagccaaaac cagaacctaa gcctgagcct aagccagaac
     1141 caaaaccaga acctaagcca aaacctcaac ctaaaccagc tccagctcca aaacctgaag
     1201 ctaagaagga agagaagaaa gcagcgccta agcaagacac caacaaattg ccatcaacag
     1261 gtgaagctac aaatccattc ttcaccgcgg cagctcttgc agttatggca ggtgcaggcg
     1321 tggctgcagt gtcaacaaga cgcaaagaaa actaagcctt ataccccagt ggtaaagctt
     1381 gagcgagaac aatttgttct cgctttttta gtgtcttaaa agcacctaca gcaatcatag
     1441 gtgcttaaca agatatgtct aacgattgct atcagctgta gagaataaaa aggagagact
     1501 aagccttgct cacaagctac ttagaccgaa ggagctttag gatttctatg atttgctgag
     1561 gggagtcctt acagccgcag ctgatccact taatgatgat gacctcaata gaggcaatgt
     1621 atagctcaaa aacatatttt tgggtaactt caggataatc ttgtgattct gcacaattca
     1681 tgaggttgga ataggaaata atatccctaa tataatgatt aaaaatttta taaatattag
     1741 gataataaag gattaagctt tgcatgacct cctgattgtc agagaggtag tttaggattt
     1801 ttaaggtaat agttgtatca agtgatgggg attggtaaat gatagaggtg atatcatcta
     1861 ggtaaacgcc gatcatttcc ctatctaagt ccttcttaga gttgaaataa tgttaaaagg
     1921 ttgttcgact gatattagaa gccttgctaa tatctgatac agtaatactg tccttatcct
     1981 tgtattgtag tagtcggcag tagcttttaa ttattttttt acaagtttgt ttatttttat
     2041 ccattgtatc attaactcct taaaattgaa cattaatgtt aattttgtac ataatatttt
     2101 ttgctaacat tatacaatga tgaacgtgat ttgtaaaatt aaattttgca aatcaataat
     2161 gtaaaaggag gattttgttt gaaacaactg acaaagatcg ttagtgtggt cttgttgctg
     2221 gtctttaccc ttagtgctag cctgcacaag gttcgggcaa ctaatcttag tgacaacatc
     2281 acatcattga cggttgcttc ttcatcactc cgagatggag agagaacgac ggtaaaggtt
     2341 gcgtttgatg acaaaaaaca gaaaatcaag gcaggggata cgatagaggt cacctggcct
     2401 acaagtggta atgtctacat tcagggcttt aataaaacca taccgcttaa tattagaggg
     2461 gtagatgttg gtaccttgga ggtcacgcta gacaaggctg ttttcacatt caatcaaaat
     2521 attgaaacaa tgcatgatgt ctctggttgg ggagagtttg atattactgt tagaaatgtg
     2581 acacaaacca ccgctgaaac atcaggaacg accacagtaa aggtaggcaa tcgcactgct
     2641 actatcactg ttactaagcc tgaggcaggc actggtacca gctcatttta ttataagact
     2701 ggtgatatgc agcccaatga tactgagcgt gtgagatggt tcctgctgat taacaacaac
     2761 aaggaatggg tggccaatac tgttacagtc gaagacgata ttcaaggtgg tcaaaccttg
     2821 gatatgagca gctttgacat caccgtatct ggttatcgta acgagcgctt cgttggggaa
     2881 aacgctctga cagagtttca tacaacattt ccaaattctg tcattacggc aacagataat
     2941 cacattagtg tgcggttaga tcaatatgat gcctcacaaa acactgtcaa cattgcttat
     3001 aagacaaaga taacggactt tgaccaaaaa gaatttgcca acaacagtaa aatctggtac
     3061 cagattttat acaaggatca ggtatcgggt caagagtcaa accaccaagt agccaatatc
     3121 aatgctaacg gcggggttga tggcagtcgc tataccagct ttactgtcaa gaaaatttgg
     3181 aatgacaagg aaaatcaaga cggtaagcgt ccaaagacta ttactgttca gctttacgcc
     3241 aatgatcaga aagttaatga taagaccatt gaattgagtg atactaatag ctggcaagca
     3301 agttttggta agctggataa gtatgacagt cagaaccaaa aaattaccta cagtgtcaag
     3361 gaagtgatgg ttcctgttgg ctaccaatcg caggttgagg gggatagtgg agtaggattt
     3421 accattacca acacctatac accagaggtc attagcatta ccggtcaaaa aacttgggac
     3481 gacagggaaa accaagacgg taaacgtcct aaggagatta cggttcgttt attggcaaat
     3541 gacgctgcaa ctgacaaggt agcaactgct tcagagcaaa ccggctggaa gtatacattt
     3601 accaatctac cgaaatacaa agatggtaaa cagatcacct acacgatcca agaggaccct
     3661 gtggcagatt acaccacaac cattcaggga tttgatatta ccaatcatca tgaggtagcc
     3721 ttgaccagcc taaaggtcat caaggtttgg aatgataagg acgattatta ccataaacgt
     3781 cccaaggaga ttaccatttt gctaaaggca gatggcaagg tgattcgtga acatcagatg
     3841 acaccggatc agcaaggaaa atgggaatac acctttgacc agctgccggt ctatcaggca
     3901 ggcaagaaaa tcagctacag cattgaggaa aaacaggttg ctggctatca agcccctgtc
     3961 tatgaggttg atgaaggctt gaagcaggtc actgtaacca acacccttaa cccaagctac
     4021 aagctgcctg acaccggagg acaaggagtg aaatggtacc tgttaatcgg tggcggtttt
     4081 atcatcgtcg caatccttgt actgatcagc ctttatcaaa aacacaagcg ccataacatg
     4141 tcaaaaccat aacatgtaat agaggagaga gagctatgaa aacaatcaaa ttaatcttga
     4201 cgagcttgct tgtcaccttc ctaacaatgc tgtcaggaaa ggcatttgct gatacagcaa
     4261 gctataccat cactgttgag ggagctacag caggtcacac ctatgaggct tatcagattt
     4321 tcaagggtga cttgtttgac agtaccctat caaacatcac atggggaggt ggtgttacac
     4381 cttttgaatt tgatggttca aaagacgctg ctaagattgc agagggattg aaggaagcaa
     4441 atgcagctgc ctttgccaag gaagcaggta agcacttgac agcaaccatt gcaggaacag
     4501 gaacacatgc aatcaccgtt aacgaggctg gctactacct catcaaggac aaaaatgatt
     4561 ctcaaacagg caagcatgac gcctacacct catttgtcct gaaggttgtt aaaaacacca
     4621 gcttcaaacc aaaatctgct atcccaacag tccttaaaaa ggtcaaggac cgtaatgaca
     4681 agacaggtct tgagacaggc tggcaagatt cagctgacta tgacaaaaat gacaaggtgc
     4741 cattccagct aaccgcaacc ctaccgtcaa attacgatgc ctttcaagaa tactaccttg
     4801 aatttgtaga taccttatca aaagggctaa gctacaacaa agacgccaag gtctatgtgg
     4861 ttaatggaga tactcgtcaa gatattacta attcatttac agttagtgaa gatggttcat
     4921 cttttaaaat caataaccta aaggctgttc agggagtaac aataacagct accagtaaga
     4981 tcgttgtcga atacactgct accctcaatg accaagcggc catcggcaaa aaaggaaatc
     5041 caaacgaagt tgctttgaaa tactcaaacg atccaaacgc tcttggaaaa ggagaggagt
     5101 ctccaaaagg ggagacacca aaagacaagg ttatcgtttt cacctataaa actatcatca
     5161 ataaggttga tcaagatcaa aaagccctaa aaggtgcagg ctttaccctt tataagctgg
     5221 tcaaaggtga taatggcgag gaaaaatatc aaatagtcca agaaattaaa gcaggggata
     5281 caactagctt tgagtttgtt ggacttgacg ctggtgatta caagctcagc gaaacaacaa
     5341 cacctggcgg ttacaacact attgcagatg tcatgttcag cattgtagcg cagcatgaaa
     5401 ccgagtcaga cgatcctcag ttgactagcc taaccgttga caaagcaact ggcttcactg
     5461 ctgatacaga agctggtacc gtatccgcaa ctattgttaa taaaaaaggg tctatcctcc
     5521 cttcgacagg aagtatcgga acaaccatgc tctatgtgtt tggagtaatg ctaatgacaa
     5581 tatcaacgct gtttatcttt cgtcagaaac agcaataaga tcgtgtgagt aggtaaaaag
     5641 aagtggatag acgtcttacc aagacctatt cacctctttt tttgatagag gctatagaat
     5701 gaagaaaagt gtcatttttt ggagtgtgat tttggtggca ggctgtctga ttgtccttta
     5761 ccccaccctt agtaactatt ggaatgcaca gcaccaatca cagctcatcg ctgactatgt
     5821 ctcaagcacg caagctttga gacataagga tagtcagctc atgctagaag cagccaatca
     5881 gtacaatcag cagctaaaag ctaaccatga tcctgattta accttgaccg atagtgaggc
     5941 agaagcctat cagcagcagc tggatctgac aaatacaggt atcatggcct acatagatat
     6001 tccaaaggtg catgagcggc tgccgattta tcatggcacc gatgaggaga tcctacaggt
     6061 ggctatcggt catcttgcag gcacctcttt gcctgtaggt ggcaagggaa cacatgctgt
     6121 catctcagga catcgagggt taccctctgc caagctattt accaatattg ataagctgag
     6181 gattaacgat acctttacca tcaccagtct taataggact atgacctatc aggtggataa
     6241 gattgctacc gttttgcctg atgatgtcag cctcttaagg atagaggagg ggaaggatct
     6301 ggtaaccttg gtcacctgta ccccctacgg tgtcaacacg catcggctct tggtcagagg
     6361 gcatcgtatc aaaacagcga caccaaccgc tgcaagagga tctcaaaagc ctagtaggct
     6421 aatcctctgg ctcttgctaa tcagtgcatt agggctatct ctcgtactaa taggcacttg
     6481 gcgctggcgt aggaggtcta aagcatgagc aggctttcca gaagcaacta agtcaaatca
     6541 tcaacccttg ataggttact gaggacctat caggggattt tttagtgcta aattgcgact
     6601 atgattaaaa acacagaaat cgtttttttt tcttagtgac cgaaaacgct ttaaaagagc
     6661 gagcatttgg agccttcaaa agtgacatct gagcataaca tgataaaatt gacttataaa
     6721 acctaataaa atgataaaag gaggagagtt aacgacaaaa tattagatat ttatttaatt
     6781 tgttgttttt gaaaacgttt tataataaga aaggatagca tgatgaaaaa acaatcattc
     6841 acacactcac gtaaacctaa attcggtatg agaaaattat ctattggcct tgcctcatgt
     6901 atgctaggaa tgatgttcct aacaacagga catgtttctg gtgaggtagt tgaagtttgg
     6961 cctaatgggc aaaatcctaa tggtaaaata gaaattctaa gtcaaactga gcactctgag
     7021 catttacaga aattacgcga tattgaagat ttccaagctc aaaagcaagc tgatcatgtt
     7081 cgttacacta aatggttaga tggggtaact gttgatgagc atgaattcag aaaaatcaag
     7141 gaatatgaca cagaatatta tgtaacacct cttttaagtg gtaaaggtta ctatgatatc
     7201 aataaagatt tcaatcaaga tagtgataaa tgtgctgccg ctgtagcggc taatatgttc
     7261 cattattggt ttgatagaaa tagagacagt attaatcgtt tcttaagtca aagtccaggt
     7321 gaaaatggtg ttattaaact tgaaaatgaa aaaacaatag aagtatcaaa atttttagaa
     7381 acttaccgta gtgatggtga ttatcttgat aaaagtccgt tttttgacct tatcagtaac
     7441 agctttaaag gtcctgtttg ggcaaataag ctattggatg cttacattaa cggctatggt
     7501 tatatccata aatttgctaa aaatactcca cattctaaaa ataataatag taaatttaat
     7561 ttctttaaaa aagtatttga tggtaatctc ttgacagata ttcaccaaat ttttgattat
     7621 aacacttttt cagataaatt aagtgaggct ctctatactg gtaaagccat tggattggcc
     7681 tacggacctg gagacttgcg tcgttcacta ggtcatatta tttctgtctg gggagctgat
     7741 cttgacgatc agaatcgcgt ggtagctatt tatgtaactg attctgatga taaaaagtta
     7801 actataggaa atgagagagt tggtttgaag cgatataaag tatctagcga tgatcaaggt
     7861 cgtgctcgtc tgacgactcg tgataaagat aacacaggtg gtgaaattcg atctattgaa
     7921 acattagata tgggtacaca agagtgggca gattacttca acaagacaga aaaataacaa
     7981 taacccctac acatatatga ttactccaga taaagcacac agcaatagac tcagccagta
     8041 aggaaaggac gataacaaaa cgatgctaac aaaccaaacg gggtacaggc atagacttag
     8101 taagcagaag ctacctatca gcatggtttc ctgcttgcta ggaatggggg tgctaacctc
     8161 tccaacatta atctcagctg atgatagttc tcctactatc atcattaaat cgggtgcagg
     8221 tatgacaatt gatcctcaat taccgaaaac tctcctttct aaacccgaag agaaaccaga
     8281 ggaaacacct aaacttccag atgagcgaca ttatggtgat gatgtcagac cggaagaaac
     8341 accaaagctt ccagacgaga gacattatgg tgacgatata aaaccggaag agatgccaaa
     8401 gctcccagat gagcgacatt atggtgatga catcaggaag ccgaaaccgg aggatactcc
     8461 aaagccacct aatgaaagcg gtcaaggtaa tgacttaaaa gaagatttgg agcttaaaaa
     8521 gcaacgtcga gagcttacag agcagcttcg tgctttaaaa actattgagg aagttttaga
     8581 gttcctgaga aaaccaattc ctggatttgt aacagatgaa gattggaatt tcttagtatc
     8641 atttgtagaa aaaggcccag aaaataaaac ttttgaagta gataaattaa aattactaga
     8701 aatcttctca acctcacaag gtcatagagt ttggttaggt taccttattc tggaaga
//
LOCUS       DARYUW010000072         8410 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYUW010000072 DARYUW010000000
VERSION     DARYUW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8410
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            71..1468
                     /locus_tag="TVW11_001743"
     CDS             71..1468
                     /locus_tag="TVW11_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1365817.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
     gene            complement(1550..2011)
                     /locus_tag="TVW11_001744"
     CDS             complement(1550..2011)
                     /locus_tag="TVW11_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1365818.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(2055..3131)
                     /locus_tag="TVW11_001745"
     CDS             complement(2055..3131)
                     /locus_tag="TVW11_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1365819.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(3422..6244)
                     /gene="uvrA"
                     /locus_tag="TVW11_001746"
     CDS             complement(3422..6244)
                     /gene="uvrA"
                     /locus_tag="TVW11_001746"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1365820.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            6440..7384
                     /locus_tag="TVW11_001747"
     CDS             6440..7384
                     /locus_tag="TVW11_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1365821.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            7643..8293
                     /locus_tag="TVW11_001748"
     CDS             7643..8293
                     /locus_tag="TVW11_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1365822.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         2532 a         2096 c         1637 g         2145 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 agacattgtc attttcgatt gacatttatg accattatca gccttcggcc taaggctcaa
     1561 cagcgccacc caagataatc tgaggcacat catgctgaac ataagcaacc ccttttttat
     1621 ccattagctc aatggcaaaa gggtggggac gataatggga tttataggtg atcttgcaaa
     1681 taccggcctg aaggagggcc ttagtgcaat tgatacaagg aaagtgcgtg acataaatct
     1741 ctgttccagc agttgaaatg ccctccttag cacattgaat caaagcattc atctctgcat
     1801 gaacagttct gatacaatgc ccttcttcca tataatgacc ggcttcatta cagttatcag
     1861 tcgccgacac gccaccgtta tagcctgtcg caataatgcg attgtccttg accaagactg
     1921 caccgacaaa tgctcgatcg caggttgatc gcttagatat cagctctgca tttgccataa
     1981 aataatcttg ccatgatagc ctatctgtca tgctttgtct cctaatccct tctaactcac
     2041 agcagctaac aagcctacgt taaaacaatc aattcctttg gtgccttggt taagacctga
     2101 cagcctgttt ctgtgatgac aagatcgtcc tcaatacgca caccgtattt gccgtctaaa
     2161 tagatacccg gttcatctgt caccaccata ccagctagaa gcctttgatc tgtcttagca
     2221 aaaaatggat cctcatgaat atcaagtccg atcccatgac caatgccatg tgtaaagtga
     2281 ctgccatatc ctgcctcagt aatgagctga cgaggaatag catcaaactc acgataggtc
     2341 atgcctgcac cagcctttgc aatcaaagcc tgattagctg caagaaccag ctcataaatc
     2401 tcacgctcct ggtctgtcac ctgtccgata tgaatagtcc ttgtcatatc actcacataa
     2461 tgctgataat aacagccaaa gtcaagcgtc aaagtctctc cctgctgaat gattttatct
     2521 gtagcacgac catgaggcat ggcagaacga tagcctgagg ctgcaatggt gtcaaaggaa
     2581 atgcctgagg caccgtattg acgcatgcga aaatccaaga aattagccac ttcaagctca
     2641 cttgtctgcc ccggcttaat aaagtccaag acatcacaga aggccttgtc tgaaatcgag
     2701 caggctttag caataatgtc aatctcagaa gcgtccttaa tcagacgaag cgcttcaata
     2761 aagcctgatt gcggcagcaa agtcacctct gaaaaggctg cctgaaggct ttgagaaaag
     2821 gaaaaggaca cctgatcctc aaaggctaga ctgctaagct tgtccgcctg taggattgca
     2881 gcaatttcag ccagcggtgt gcggctctca atgatatcaa agccctcaat actagcctta
     2941 gcaattaagg tataacgcga atctgtaata aaaacacgcc gctttggact gataaagacc
     3001 gtagctgagg tccctgaaaa gcctgtcagg taataaatat tagtcagatt agtaattaaa
     3061 atagcctcca agcctttttt ttccagtaat gcttggcaat tgcttaagcg ctgtgctaaa
     3121 aatgatgaca tggtaatctc ctttatcgac aaaactacct taagtttacc atgatttcaa
     3181 cgcttttaaa agcaagaccc attaaagaca gccaacaaaa aaagcatttc tgacagtgga
     3241 ccaaaaggct aatcagctta gccgccacta ccaaaaatac cctttaaata tcacccacgc
     3301 cccccgcgaa gagagctact ggctatctat tatttaaatt aaaatcaccc ctcatttcaa
     3361 tccatgccct atcatcgttc atacgaagat cactctgtca attgatgtca ggcctgcaac
     3421 tttacaattt cagcttcagg tactgccctg tgtagctttc ctcaacagcg gcaacctctt
     3481 caggagtccc agttgcaacc agttgacctc caccaacacc gccttctgga ccaaggtcaa
     3541 taatatggtc tgccgacttg atgacatcta aattgtgctc aatcactaaa acagtattgc
     3601 catcatcaac aaagcgctct aaaaccttca gtaatcgcgc aatgtcatct gtatgcagcc
     3661 ccgtcgttgg ctcatctaaa atatacaagc ttttaccagt tgaacgcttg tgcaattcac
     3721 tagccagctt catgcgctgg gcctcgccac ctgatagggt tgtcgctggc tgccctagag
     3781 taacatagcc aagcccaacg tccttaatgg tctgaatttt acgagcaatc tttggaatag
     3841 ctgagaaaaa taccagagca tcatctaccg tcatatccaa gatttcagca atgtttttgc
     3901 ccttataatg gacctccaac gtctctgaat tatagcgtct gccatgacaa acatcacatg
     3961 gaacgtaaac atctggtaaa aaatgcatct caatcttgat aatcccatct ccagagcagg
     4021 cttcacagcg gcctcccttc acattaaagg agaagcgccc ttttttgtag ccacgaatct
     4081 tggcttcatt agtctgggca aagagctctc gaatatcatc aaaaacaccg gtataggtgg
     4141 caggattaga gcgcggtgtc cgcccaattg ggctttgatc aatatcaatc aaccgttcca
     4201 aatggtcaat gccagtgata gacctatgct tgcctggctt ttcagagtta cggtttagcc
     4261 tttgagccac tgcttttttg agaatgctat taaccagcgt tgattttcct gagccagaga
     4321 ccccagtcac tgcaataaat ttctccagag gaaacctcac atcaagattc tgcagattgt
     4381 tttgggctgc tcccttgata tcaatatagc gaccattgcc agcacgtcgc tccaaaggaa
     4441 cgggtattga tttgcgtcca gacaggtatt gaccagtgat agacctttta tgccgagcaa
     4501 cctgctgagg cgttccagag gcaacaatct gcccgccaaa gtccccagca ccaggtccca
     4561 catcaatcag ccaatctgcc tgcatcatgg tatcctcatc gtgctcaacc acaatcaagg
     4621 tatttcccaa gtcacgcatt tttttcaagc tatcaatcaa gcgatcgtta tctcgctggt
     4681 gcagaccaat agaaggctcg tccaaaacgt aaaggacacc tgacagatta gagccaattt
     4741 gcgttgccaa acggatacgc tgactctctc caccagacaa ggtgcctgcc gagcgagaca
     4801 aggtcagata attcagaccg acattattca aaaaggtcag ccgatcatga atttccttga
     4861 taattggctt tgcaatggtg ctttcattgt ctgacagctc aagccgatct agcagctgca
     4921 gatggtctgc aatagatagc tctgacacct gaccgatcgt caagccatac tcaccaccaa
     4981 cacgcacaca cagggcttga tcattgaggc gatagccatg acagctcgca caggtcaatt
     5041 cgttcatata gcctcgcatg acattgcggg tatagtcact gttagtctca tggtagcgac
     5101 ggttaatatt tgtcacaacc ccttcaaagg gaatatcaat gctgcgctcg ccaccaaaat
     5161 cattgacata gtgaaaatgg aactcctgat cacctgagcc atacaggatc agctcctttt
     5221 cctgctcgct caattgctca aaaggcttgt ccatatcaac accaaagctc tgcattgcct
     5281 gctcaagcat ggttgggtaa taatttgacg agataggatt ccaaggagca agagccccct
     5341 ctctcaaggt cttgctggga tcaggaacaa ctagatccaa atccacctcc agcttgatcc
     5401 ctaagccatc acaggtaggg caagagccaa agggcgcgtt aaatgaaaaa agacgaggct
     5461 ctagctctgg cactgtaaaa ccacataccg gacaggaata atactctgaa aacagcaact
     5521 cattgccgtc catcgtatca atcatcagat agccatctcc caagcgaagc gcagcctcta
     5581 tcgaatcaaa aagacgactg cggatcccgt ccttattgac caagcgatca atgacgacct
     5641 ctatattgtg cattttgctt ttggataatg ctggtacctc tgacacatca aaaatctctc
     5701 catcaacacg cacgcgcaca taaccgtcct tttgaatttt ctcaaacact gtcttgtgct
     5761 gacccttttt acgacggaca agaggcgcca aaatctgcat acgcgtccgc tcaggcaact
     5821 ctagcacctg ctcaacaatc tgctccaccg aggaagccgt aatagcccca tgcccattga
     5881 tacaataggg agtccccaca cgcgcataaa gaagcctgag gtaatcattg atttctgtca
     5941 ccgtaccaac ggttgatcta ggattcttgc tggttgtttt ttggtcaata gaaatagcag
     6001 gactaagccc gtctatagaa tccacatcag gcttttccat gttgcctaaa aattgcctag
     6061 cataggctga caggctctcc acatagcgac gttgtccctc agcatagatg gtatcaaagg
     6121 caaggctaga ttttccagat cctgataagc cggtcaccac aacgagctta tcacgtggaa
     6181 tctccacatc aatatttttt aaattgtggg cacgcgcccc acgaataatc aatttatctt
     6241 gcatgctctt gtgcccccag gcaccctcct catcgagatt tattccatta taacaaaaat
     6301 ttctaataat cagttgcccc aaacaccatg aatttgtagt ataatagaca ggtattgagt
     6361 gtttttcaaa aaggcttcgt ctacctgatg acaagaagct cacttcaata ctgactaatc
     6421 acaaaaagga gggcttgtca tgaaacaaat gtttctttca tcggcaattg aattcaaaga
     6481 aatcgaaaca ttcgagccag gtgcttggat caaattggtc aacccctccc aggaagagtc
     6541 tatcgccatt gccgatcaat ttaacattga tatttctgac ctgcgtgccc ctttggacgt
     6601 tgaagaaacc tcacgtattg ctgttgagga cgactacacc ttgattatcg tcgacgttcc
     6661 ggtctatgag gagcgcaaca acaaaagcta ctatgtgacc atgcctttgg gaattatcgt
     6721 cactgaaagc gcggtaatca ccacctgcct gcatgacatg acactttttg atcagtttca
     6781 taagcgtaag gttaaaaact tttacacctt tatgaagaca cgttttgtct ttcaaattct
     6841 ctaccgcaat gccgagcttt tcctaaccgc actaagaaca attgaccgac aaagcgaacg
     6901 cttggaggct cagcttgagg cagcaacccg aaacgaagaa ttaatcgaca tgatggagct
     6961 tgaaaaatcc atcgtctacc taaaggcctc cctaaagttc aacgagcgca ttgtcaaaaa
     7021 attatccagc tcaaccagct cactcaaaaa atatattgag gacgaggacc tgcttgagga
     7081 tacactgatt gagacccaac aggctattga gatggctggc atttatgaaa atgtcttaaa
     7141 tgccatgacc gaaacaaccg cctcaatcat taacaacaat cagaacacca tcatgaaaac
     7201 attggctctg atgacgatgg ctctagatat tccgacagtg atcttctcag cctacggcat
     7261 gaactttcag gataattggc tgccgctcaa tggccttagc catgccttct ggtatattgt
     7321 cctgctggca accctgctca gcagctttgt tgttatttat tttattagaa aaaaatggtt
     7381 ttaataaccc catttccaac tgaaaaagct actcctgagc tctacctgta gacagctcat
     7441 cagctaaagc aggcactact actgctaaag caaacaatcg tcccagcaag taacggtagc
     7501 tactactgct tgatcgtatg atcaagcgca acatatcagc tgccatacta gctggcaaag
     7561 caagccagca aggcgccctt gaggcattat cccaggctag ccctgcttac aatcatcaca
     7621 tcatatagga gaatcccctg tcatggactt acaacagctt accaaaaaaa atcaagaatt
     7681 tattcatatc gccaccaatc agctcatcaa agatggcaaa actgatgacg acatcaaggc
     7741 acttcttgag gaggtcattc cgaccatctt agagaaccag aaaaaaggca tcactgcaag
     7801 aagcctatac ggggctccaa ctgcctgggc agcttccttt agtaaagaag caaatcaaaa
     7861 agaagccaca cccaaaaaca ccaatccatg gctgatgtgg cttgatacct cgcttctatt
     7921 tatcggtatt gttggccttt taaacagtat catgaccttc tttaatacca acactaccgt
     7981 taccgggctt gtgtccttgc ttgctcttgg ctttggaggg ggtgcttcca tgtacgccac
     8041 ctactatttt gtttatcgcc atatgggcaa ggacaagagc cttcgtccaa gctggtttaa
     8101 ggttattggt gctctgacac ttgcaatgct ggcctggata accctctatt ctgctacagc
     8161 ctttttacca aaggcgctca acccacaatt acctcctgta gcacttctca ttaccggtgc
     8221 cttagctatc ggactgcgtt acctcttgca gcgcaaatac aatatccaaa acactatggc
     8281 accgcagcgc tagcagcagc tccactgcct gaggaagcac ttccctattc tctcttgagg
     8341 gcagttagcc ttttcatacc atattgctgg caacaccaga cactgatcta caatcgacac
     8401 tcctcaatcc
//
LOCUS       DARYUW010000073         8035 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYUW010000073 DARYUW010000000
VERSION     DARYUW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8035
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            44..793
                     /locus_tag="TVW11_001749"
     CDS             44..793
                     /locus_tag="TVW11_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365823.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            793..2127
                     /locus_tag="TVW11_001750"
     CDS             793..2127
                     /locus_tag="TVW11_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1365824.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(2249..2380)
                     /locus_tag="TVW11_001751"
     CDS             complement(2249..2380)
                     /locus_tag="TVW11_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1365825.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(2480..3838)
                     /locus_tag="TVW11_001752"
     CDS             complement(2480..3838)
                     /locus_tag="TVW11_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1365826.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            complement(3849..6005)
                     /locus_tag="TVW11_001753"
     CDS             complement(3849..6005)
                     /locus_tag="TVW11_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1365827.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            6265..6513
                     /locus_tag="TVW11_001754"
     CDS             6265..6513
                     /locus_tag="TVW11_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1365828.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            6520..6816
                     /locus_tag="TVW11_001755"
     CDS             6520..6816
                     /locus_tag="TVW11_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1365829.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            7558..7812
                     /locus_tag="TVW11_001756"
     CDS             7558..7812
                     /locus_tag="TVW11_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1365830.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            7829..8032
                     /locus_tag="TVW11_001757"
     CDS             7829..8032
                     /locus_tag="TVW11_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1365831.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
BASE COUNT         2327 a         1250 c         1792 g         2666 t
ORIGIN      
        1 tagtgctaat gcttctgcag attggatagg ggactgagtt taggtgagag tagttatttt
       61 agaagatgat atgattcagc agagatattt agaaaagctc attaaagagc ttgaggttaa
      121 gcaccagcta ttatttcaag gacttgactg ttttggaagg cctcatcagc tattaagtgc
      181 tatcaagaag aactgtggtc agcagctatt ctttttagat attgagataa aaaatgagaa
      241 caaaaaaggg cttgaggttg ctaggcaaat tcgtcagata aatccagatg cgatgattgt
      301 ttttgtaacg actcactcgg aatttatgcc cttggctttt cagtatcagg tatctgcttt
      361 ggactatatc gataaagagc tgcctcaaac tgagtttgtt caacgggtag agactgcttt
      421 attatatgct gtgcggcaaa atagtgaaac gatagcggaa agtgcttttt attttacatc
      481 tcgttatgct caggtacagg tgccttttaa tgatatcctg tatattgaga catcgtcacg
      541 agcgcatcgt gtcaatttgt atacaaaaaa ggagagaatg caatttacgg ggactttgac
      601 ggatattttg aagcaagagt ctcgtttttt gcaatgtcat cgttcttttt tgattaatca
      661 taggaatgtc gttagggtag ataagattga gcgagtggtt tattttcgaa atggctctag
      721 ctgcttaatt gctcgtagta aaatgaacag tgttttaaca acaattgaga acctacatag
      781 aggagataat taatgaagct tattttattt ttcttagaaa tgacgacaag tataggctta
      841 tcgttagtgc tcttttccaa aatcagtgga cgtcaattaa cctggcttga agttgctttc
      901 agtacttttt taagaatagg atttgctgtt tttttcacta tagctaatca tgttgccgac
      961 atttcacttc tcaattattg gagtcttcca atttatatgg tagtgatatc atggctattg
     1021 ctgcgaccct tatcaaaaac attattgata ttttatgggc tatttcctat taccctgtgg
     1081 agcctttggt accgactgct tggttttttt atcttacctc tttttaaact tgattatcat
     1141 ttaacaaatg atggattttg gggaattttt acagatatag tatctacttt gatggttttt
     1201 ctctttttgc ggtggctacg atatgatttc agagcattaa gaattaatct tttatctgat
     1261 agggataaaa gaattttagg tgtgaccaac tggtctatgg ttagctatta ttttttgatc
     1321 caattgcttg cttatttaga gtatgagcta gctgttgata cttatgccta tcgtcaatgc
     1381 atgatgcttg gctattggat tatatttatg ggaactgtgt cgagactgga ccggtcgcta
     1441 agagatacac tgcaagaaag actgaccttt caaagagagc tgcagctggc aaatattgag
     1501 agctatagtc gtcagataga ggagctttac agagaggttc gaggatttcg tcatgactat
     1561 agcaatctga ttgccacgtt aaagtttggt atagataatg atagcatgtc tattgttagg
     1621 tcagtttatc aatcggtctt taaggattca aataaacgat ttcgcaagca aaaatatgat
     1681 gttgggcgtc ttatccatgt cactgacaca gccttgaaaa gtcttttagc tgcaaaattt
     1741 agtcaggctt tagaaagtgg gatttcagta tctttagagg ttccagagga tatcagtccg
     1801 caaggcatgg agctgattga ttttcttact attgtgtcta ttttatgtga taatgctata
     1861 gaggctgctg ttgaagcttc ttcgtctaag ataacgattt cttactttac tttggacaat
     1921 aagcaactat ttatgattga aaatacaact aaggaagaga agattgatct atcctttcta
     1981 tatgatttcg gagtaagcac caagggggat aatagaggtg tgggacttta taatgctatg
     2041 gaaattatca atcgttatcc caatgtgatg attaagacta taagtcaaaa tcatgtattt
     2101 ggtcaaacac ttgagcttag gttataaaaa aacaccacta gtaaaggaaa actgtcttgc
     2161 acctatcaga tttgatgttt aggatcacat cattccgata gtgtctcagt acctttaggt
     2221 agtggtgttt tgaaaatgga gaatgttact attttagtag ttttggctta gagacattga
     2281 aaactttttg aagaccttca agccagcctc ctccagtaat ctgagttaac tgagaaggcg
     2341 ttagttcctg aaactttggt tgtctagttg gtttatccat attgaaagct ccttttaaat
     2401 actgtctatg ttattatagc ttatcttgac tctttgttgt actctatgtc ctaaatggtc
     2461 gttgaaaagc gctaaatggt tattctgtca ctttaaagag cttgtcctta taaaagtcaa
     2521 agaatgtttt tttggcaata acacttatca ctcgtccctg ctgaccatat tgaatagtag
     2581 tgctttcttt ttcagaaagt gttagtttgg ctgtaacctt aaaaagattt ccctgcttgg
     2641 ttttggtcgc tagctcatca atggttttaa tggttcccgt aatgactatc ggttgatttc
     2701 catgtctatc tagagctagc ctgacaacct ggttcttctt aaggagagaa acagattcag
     2761 agctgacata gtaagtgagc aaggcttgtt ttgtttgttt gaggctagga taaatgtagg
     2821 caatatcgtg accgattggg atactaattt tgccttcaaa agcactattg agctgaacaa
     2881 tgccactttt tgaggctttg atcaccagat tgtttacctg aagagtggct tgctccaatt
     2941 gcgccttgag ctcagtaata tgatgattga catctgttaa ctgctgagag gctgttatca
     3001 aaaactgtgt tcggagtatt tctagctttg tgttgaggct attatcatag ctggtagatt
     3061 gatgtagatt agcacgttgc ctatagaggc tatctataga ggtttttagg tttaaaagat
     3121 tttggtctat ttgaaataga agctgattgg tggcagtctc ttggtttgct tgagattgag
     3181 agagataggc atcaagggtg gcttgatgtg ggttattgga ggatagacta tcggattggt
     3241 taatgatcgc agatcgaagc tcttcatagt ctgatatttg ttgagaaaga ctatttattt
     3301 gctgattgat agcaacaata gagtcctgaa tcagctgggc ctgctggctg gtctctgcct
     3361 ttatttttga gaaaccaagg tcaatatctt gggcttggct catgaaatga ttaaaggtat
     3421 tgacgtaacc aaattgatca tcgttctgaa aaaggttctg gccttgtttt aagcttaaca
     3481 atagagtatt aaggctgctt ttttgctttt cgtaggtagc taattgtttc tcaagtacct
     3541 gcttttgaga ctcttctagg tctttagcat attgaataat agagtctcct tgtttgattg
     3601 gctggttatt ggtgagatgg ttcgcaatta taggattatt gctaatagat tggactgttg
     3661 caatgacttg agtgggagtg atttctccgt aggacgttac cgttatttct ttataaacaa
     3721 agcaagaaaa aaggataaga aaagtcaaca agagggctaa gggaattgtt aagaatgttg
     3781 tcaaatgatg atagcgtctt tggtagaatt ccgcactttt aaacatattg ggattcatga
     3841 ttgtctcctt attcactaaa taggtggtaa taaaatccac cttgtttcat taattcctgg
     3901 tggctgcctg tttcaatgat ttgcccttga ttaagaacaa caatctgatc agtgcgctct
     3961 gcgatactaa gccggtgggc aacgaaaata atcgttttgt ctgtcatgtt catgagacgg
     4021 tcaatgattt tcttttctgt cagtatgtca agtccgctgg ttgcttcatc aagaactagt
     4081 ataggagctt gggttagtaa tgctctagca agtgcaattc tctgtttttg tccgccagat
     4141 aagccagccc catcagagag ctcggtttgg tatcccattg gcatttgctc gatgtcgtga
     4201 cgaatgtcag caatctcaca ggcgttaaga atgtcttcct ggctgatgcc ttgcttggct
     4261 cccaaggtta gattttctaa gatagatcca ttaaacacat aggcttgttg tggaaggtag
     4321 ttgatgtatt gtcgaagatt ctttttatca atggtcttga gatcgttttg gttgatggtt
     4381 atacgtcctt tataaggttc aaagaaattg acgagcatct tggctagggt tgtttttcct
     4441 gagccgctga caccaacaag ggttactttt gctccctgct taatggttaa tgtaatatct
     4501 gataatgtat ccttgccaaa gccatacctg taggaaacag cttcaaactg aatgtcaccc
     4561 tgtaagagcg ataaatcgta taaggcttgc gaggctttaa attcggactc tacaagatag
     4621 acctcattga gacgattatt ggcaacctta gctgcttgga gcttggtttg aagattaatg
     4681 atattttcta aaggggttgt aaaataggca agaagtgtgt taaaggtaat taattgcccg
     4741 attgaaattt taccattaat gaccagttga gccccaaacc aaagaatgat gatattcaga
     4801 attagctgcg ctccttgctt aagtgtggct tgtaagatgg tatatttact aagcttaaaa
     4861 gacttatcaa ggtaatccac aaagtcgctg tcaatttttt ggtaacggtt ttcttcactg
     4921 gttagtgatt ttatggtttc gatcccgttg atatcttcga taatagcaga gcttagcatg
     4981 gcattgcttt gcatcacatc atgattcatt tgttcaaacg gctttataaa ggcacatatg
     5041 ataatggtat atactgggat agaaatcaga gatagcagaa aaagcctgct attttgcacc
     5101 aaaagaacac ttccgacaat agctaatata gagaggtcta gaaagaggga taaaatggtt
     5161 gaagcgagtg catcaataat agagttagca tctgtaaagc gcgaggttac ctcacctgtt
     5221 cgacgtgttg caaaaaagga catcggcaat tcgaaaatat ggcggatata ggacagaatc
     5281 acatcaatcg taagacgttg gctaaggaca gttaaaagat aatctctaga aaagctcatt
     5341 agctgctgga gtatataggt aatgatgaga ccaattgata caatccctaa ggtagatttc
     5401 agctgatttg gaatatactc gtctaaaatc ccctggagat agtatgaacc agcaatatta
     5461 atgaccgtta ccaagacaga agctaacacg atataaaata taagggttcg ctgtttaaaa
     5521 ataagcggaa agaagcctaa tagtccattt ttttggtctt tatgtggttt ataatttggc
     5581 ttaggagcaa gacatatggt gacacctgtc cattctgaag caaagcgttc cttggacatt
     5641 tttgtgacct tgaccattgg atcgggatca ccaatgataa gatagtcttt tttagatttg
     5701 tagaccacat agtagtgctg tagctttcct tctttattga catggacgat caatggatag
     5761 ggcacgtctg ccatgtcaaa gagggtcata tccgcttgaa tgggtctggt ttcaaatccc
     5821 atttccttag cagccatgac aataccgagg gctgttgtcc cttccttatt ggtttttgct
     5881 aattctctca aatgagctaa tgaataatct gaaccataat accttgcgat tgaggctaga
     5941 gcagctacgc cacaatctct ggcatctatt tgtgatacaa aggttctttt ataaaagagt
     6001 gtcattggtt ggcttccttt ctctgttgta acgactctat tgtgccacaa aagctcagaa
     6061 aaaaactgag ctagtcttga atagtcgttg aaacgtctta aatgggaata atgatattaa
     6121 cactcttttt taatcagttg cgacattacc attcaagacg tttcgacgac attttaagac
     6181 ttaaatactg aaagcagtta tttatctgct atactgggtt tgttgcttgc aacaggtaaa
     6241 aaataaatat aggagatatt cacgatgaat atgacattaa tgaaacaatt taatattata
     6301 gacgctgaca agcttgctca cattgagggt ggcggcaaag gaatttgtaa gtttgtaatg
     6361 tctggttcta atgggtatgc ctgccgatat agcaatggcg aatggggcta tattgttact
     6421 aaaagtaatt ttgaagcaac taaagatgtt attgttaatg gttggatatc ctctttagga
     6481 ggtggttatt tccatccagg gtatagaggg tagttgggta tgttgacgca agaagagata
     6541 ctaaataagg tttataattt aattttagat ccaaccttaa catcagaaga gcgagtcatt
     6601 ctggtaagat ttaaagatag agtaggggag tcaagtaact ttgacagaga agtgatgatg
     6661 ctatctgaat ctctgcgtca attagctgtt aagcagataa gagttgaaac aatgagtgta
     6721 gaaatggcta aattctataa agaaatctct acttacaaag aatgtgataa acagctaggt
     6781 agaggcctaa tatcattggg agttattagg cgataataaa acgctcatac cttatcgttg
     6841 tattggcgtt attgttttgt tgagtcacaa taggccaaat gacatgaaaa ggttgtcaat
     6901 gctattttgt gagatggcta gctgaaggta aagtaagtaa cgattgagtt gattggctaa
     6961 tcgcaggata taacaatggg tatcagttta aagctgatac ctattgtttt gtggtagtta
     7021 actatctagg gtggtttcgg acaagaagta gcttgagata attgcaaggg caataagctt
     7081 atctcatttg gttagtgatt tattttttct tacaaagaac ttatttttga gtcttattga
     7141 gcttggaaaa gaaatattat ctgcgctatt agctatcaaa tcagttgctt ttccttattt
     7201 ctagaggctt aagttagtaa gctgaggcca caaatgtatt attttcatca gctgttgatg
     7261 atgtattgct atctggaaaa ataaaatagt catttaagat tgggctattt gtcattacag
     7321 catagagcct tcagccgtca aaggaggaaa ctcagctttt gaagcaatta agacagcttt
     7381 ctcatatttg ttatgggtat taggaatttt cactgaattg gtgttaacgg ttttcgtatt
     7441 accattcaag acgtttcgac gacattttaa gacttaaata ctgaaagcga ttgtttatct
     7501 gctatactgg gtttgtcagt tgcagcagac aaaaaataaa tataggaggt attcacgatg
     7561 aatacgacat taatgaaaca atttaatatt atagacgctg acaagcttgc tcacattgaa
     7621 ggtggaaaga ataattggca agctaatgtt tgggaaggtg gtaccgctgc tgttagtggc
     7681 tgggggttag ggacagctat ttgtgctgca agtggtgccg gtgctccatt tatgggagca
     7741 tgtggttaca ttggagccaa atttggcgta tcattgtggg caggagtaac aggagcaaca
     7801 ggtggatttt aatcaagaga ggttttttat gactcattat tatcaaatca aagaagaaga
     7861 acttaacgac atttgtggag ggaaccctgc cggtgcagca gtagtaggtg gtttgacctg
     7921 tgctgttgga ggtataaagt tgggaagtag gattggacct tggggagctg ttatcggagg
     7981 agttggaagt gcagctgttt gtggttattt agcctataag gcttcatcat aatat
//
LOCUS       DARYUW010000074         7707 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYUW010000074 DARYUW010000000
VERSION     DARYUW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7707
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            77..1273
                     /locus_tag="TVW11_001758"
     CDS             77..1273
                     /locus_tag="TVW11_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1365832.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSAAAQG
                     LEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETSKTGTFTLDAAEINVR
                     RWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDKDGNIIS
                     LWGKLN"
     gene            1558..2073
                     /locus_tag="TVW11_001759"
     CDS             1558..2073
                     /locus_tag="TVW11_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365833.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
     gene            2269..2481
                     /locus_tag="TVW11_001760"
     CDS             2269..2481
                     /locus_tag="TVW11_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1365834.1"
                     /translation="MLTYDEFKQAVDDGYITGDTVAIVRKNGQIFDYVLPGEKVQPWE
                     VVTEEKVENVLRELDWRSVKSRSKLL"
     gene            2733..2936
                     /locus_tag="TVW11_001761"
     CDS             2733..2936
                     /locus_tag="TVW11_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1365835.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            3106..3567
                     /locus_tag="TVW11_001762"
     CDS             3106..3567
                     /locus_tag="TVW11_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1365836.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            3567..6008
                     /locus_tag="TVW11_001763"
     CDS             3567..6008
                     /locus_tag="TVW11_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1365837.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6356..6442)
                     /locus_tag="TVW11_001764"
     CDS             complement(6356..6442)
                     /locus_tag="TVW11_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1365838.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            6781..7212
                     /locus_tag="TVW11_001765"
     CDS             6781..7212
                     /locus_tag="TVW11_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365839.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            7214..>7707
                     /locus_tag="TVW11_001766"
     CDS             7214..>7707
                     /locus_tag="TVW11_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365840.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIV"
BASE COUNT         2345 a         1351 c         1787 g         2224 t
ORIGIN      
        1 tagcaatcac aatactgtat ttaccgctat ctgtgattgc tctgattgtt tatccgtttt
       61 tagataagga ggacagatga cctttttaga taagattaag caaggctgct tagatggctg
      121 gaccaagtac aaaatcttgc catctttaac agcagcacag gcaatccttg agagtggttg
      181 gggcaagtac gccccacata acgctctatt tggtatcaag gcagatagct cttggacggg
      241 taagtcattt aatacaaaaa ctcaggagga gtatcagccg ggtgttgtaa cggatattgt
      301 agatcgtttt agggcctatg atagctggga cgagtcgatc cttgatcatg gtcagttttt
      361 agtagataac ccacgataca aatcagttgt cggggagact gactataaaa aggcttgtca
      421 tgcaataaaa gcagccggtt atgccactgc aagtgattat gcggagctgc ttatccagtt
      481 gattgaggaa aacaacttgc aaaaatggga taaggaagcc ttaaaaacta ataaggaggt
      541 aacgatgaca accgcaaatg agattgtaca atactgtgtt gaccttgcca actcaggtat
      601 gggagttgat aaagatggct gttttgggac gcagtgtgcg gacttgccat gttttatcgt
      661 caaaaactgg ttcgggattg acttatgggg gaatgcgatt gacctgttaa acagtgcagc
      721 agcgcaaggt ctagaggtta tctataacgc acctggagtt aatccaaaag ctagtgactt
      781 atttgtcatg gaggtagctg gcagtcctta tggacacaca ggagctgtta ttgaggacag
      841 tgatggctat accattaaaa ctgttgagca aaacattgac ggcaactggg acagtttaca
      901 agtaggtggc cctgctcgct ttaatactcg tgactttact ggcgttgtcg gctggattag
      961 gttacctgtt gaccatacta accagacagt agatacagca ccgcaaacgt ctgacaccat
     1021 cgtggagacg tcaaaaacgg gtacttttac acttgacgcc gcagagatca acgtccgccg
     1081 ctggccgaat ttaaccagtg aggtagtaga tagttataag caaggccaaa ccgttagctt
     1141 tgatagtgag ggttacgcca atggctacta ctggattagc tatgtcggag gctcaggtaa
     1201 gcgtaattat atggcaattg gtcctactga caaagacggg aatattatca gtctttgggg
     1261 taaattaaat taggaggtaa agatccgaga taagacaaaa ccgctctctt aatcgagggc
     1321 ggttttttgt gtcttaaaga ttctatattt gacgaatgca acatattatg taataatgta
     1381 aatgaacata aatagtaaaa gcattatctc tatgttccga cctttccatg tcgttaaact
     1441 ctcgccattt tggcaatgag ggggcggagg gacgcgctcg ttaacagaag tatcccgttg
     1501 gcaatgcgtc ctaccaatac ccagttggta ggatttttta tttttagaag gcaaataatg
     1561 aagagtaaaa aattagtatt cggtcagatt gatttaaaca tgtgtcgaga tttcgatttg
     1621 gtacaagctt tagactatga ttttaaagag aagaagctat ataacaaagg ccgaggtttt
     1681 gccattgtgt tggtaagtat ccaaaatcta acttttgcaa tccctttgag aagtaatatt
     1741 cctaaaaaat atcaactaaa atataaatta agagactcta aaaaatacgg atgcgtagag
     1801 gggcttgata ttggcaaagc tctagtggtt gaagatccaa aatatatttt aaacagaacg
     1861 ttcaaattac gagagcaggt tgattatttt aagattgttg ataatgatat acttattgtt
     1921 aacaagttga taaaggctat catagattat aatcaagctg tagctaatag tgatcaacat
     1981 aaattaacag atcctaaacg tttcaaattc tctacattcc caaactatac cgacagatta
     2041 aaaagcatta ccgatgccga ttatcttcgt tgacaccctc gcacaatcat gaaccaatta
     2101 ccatagtaag aattagccaa aataaaaatc aaccgctcag attatttctg ggcggttttt
     2161 tgtgtttcac acacatgtat tcacacattg gcatatccgt tataacggac ttgttaaaat
     2221 tagtccatta aactagactt tttacgaata ataaggtagg aggtatttat gttaacatac
     2281 gacgagttta agcaagcagt cgatgacgga tatataacag gagacacagt agcgattgtg
     2341 cgtaaaaacg gacagatatt tgattatgtg ttgccagggg agaaagtgca gccttgggaa
     2401 gtggtgaccg aggaaaaagt agaaaatgtg ctgagggagt tagattggcg gtcggtcaaa
     2461 agtcggtcaa agttactcta aagcactgat atcaatgcat ctaaaatccg tctaccgcct
     2521 tagattgtta aagcaaggtc agcatgactt tgctttttta cattttagca ggtggagtag
     2581 aaaagctgtc attgtgaggg gtatgtgttg acagtggctg ccattcgtgt tacactgagc
     2641 gagtaaatta gtttttgaat tagtagttgt gttttggcat ctttatttct ctctatgttt
     2701 acaaatgcgt tatagaaagg aagtggatga ctatggcaca aggtacagtc aagtggttta
     2761 atgctgaaaa gggctttggc tttatttcaa ctgaaaatgg tcaagatgtt tttgcacatt
     2821 tttcagcaat ccagtctgac ggctttagat cgttagacga gggacaaagg gtgacgtttg
     2881 atgttgaaga cggacagcgc ggtcctcagg cagtaaatat cactaaattg tcttaatcta
     2941 gtgagcagat aataggggat gggtgttgtt gatagcacct gtccttttac attctagtga
     3001 tttccatttg cttttagtga ctgctatttg atataatgtt agtcagtttt agtcaaataa
     3061 aggcttaaag cagcaaatga atcgttttag caaaggagtg acggcatgcc aacaaaaaat
     3121 acttccgata gtatcgaaga atatatcaaa gaattgttag cccaatcagg aatcgcagag
     3181 atcaagcgct ccatgctggc ggattccttt caagtagtac caagccagat taattatgtg
     3241 atcaagaccc gttttacaga aagcagaggc tatgaggtag aaagtaagcg tggtggtggt
     3301 ggctacattc gtattgctaa ggttcatttt tcggataagc accacctgat tggtacgttg
     3361 atcgcttcta ttgatgattg tttaagcgag caggccttta cagattcgat tcagctgctt
     3421 tttgatgagc aactgttaac agagcgcgaa ggaaacatta tcttagctgt agcttctaat
     3481 gatgttttgg gacatcaagc accagaaatt cgtgctcgta tgctttatcg cctattgcaa
     3541 cgaattgata gaaagggaag caattagtga tgatttattc attaaagatg caagacattt
     3601 ttaatcaggc tcaatttcaa gcagagcgct ttgatagtcc ttaccttgag acctggcata
     3661 ttttattagc tatggtagct gttgaccatt ccttagcggc catggtgtta agcgaatttg
     3721 aacgaaagat tagggctgaa gagtatgagg ctgctgctat tttagccatg ggaaaaagtc
     3781 ccaaagaggt gacttctgtc caattcaagc cacaatccaa ggccttatca gaaatactag
     3841 catttgctca tgctatctgt caggttatca atgagcatga ggttggctca gagcatgtac
     3901 tctttgctat tttgctcaat ccggatatta tggccagtcg tctgttagaa ttggcaggct
     3961 acaggctcaa ggattctggc aagggagagc ctaggtttgc ggatttacgt aaggctattg
     4021 agctaaatgc cggctatagc aaggaaacta ttaaggcgat tcatgagttg cgtaagccta
     4081 aaaagagtaa atcagtaggc accttttctg aaatgatgaa gccacagagt acagctggtg
     4141 agctatcaga ctttacaaga gacctgacag agatggcaag acagggctta ttagagccag
     4201 tcatcggacg agaaaaagag gtgtcacgta tggttcaggt gctttgtcgt aagacgaaaa
     4261 ataatcctgt tcttgttggt gatgcgggtg tcggaaaaac tgctctagct tatggcttag
     4321 cgcagcgaat tgctaatgga gccattcctt atgaattaca agacatgcgt gtcttggagc
     4381 ttgacatgat gagtgtggtt gcaggtaccc gttttcgtgg ggattttgaa gagcgcatga
     4441 atcaactcat tgacgatatt gaagcagatg gtaagatcat tttgtttgtc gatgagctac
     4501 ataccattat gggatcagga agtggtattg acagcacact tgatgccgct aatattctaa
     4561 agccagccct ttctcgcggt accctgcata tggttggcgc tacaactcaa gaggaatatc
     4621 aaaagcacat tgaaaaggac gcagcccttt ctcgtcgctt tgccaagata ttgattgagg
     4681 agcctagtgt tgaggacgct tatcagattt tgcttggctt gaagccttcc tatgaacagt
     4741 accataatgt aacaatctct gatacagctg tccatactgc tgtgaagctg gctcggcgct
     4801 atttgacaag taagcagctt ccagactcag cgattgatct gcttgatgaa gccagtgcga
     4861 tggtgcaaag tatggttaaa aagacgcagc ctgactttat aacaccgctt gatcaagccc
     4921 tgcttgatgg tgatatgagc aaggtgtcag cccttttagt caaagaggat aagcaaccaa
     4981 agctaaaacc aacagcagtt actgaagatg atatgttaca caccttaagc aagctatcag
     5041 gtattcccct agaaaaacta actcaggcgg atagtaaaaa atacctgaat ctggaaaagg
     5101 aattgcataa gcgtgttgtt ggtcaggaaa tggctgtttc tgctattgca cgagccattc
     5161 gtcgtaacca gtcaggcatt cgcacaggca ggcgtccgat tggctccttt atgtttcttg
     5221 gtccaactgg tgtcggaaaa acagagctag caaaggcctt ggccgaatta ctctttgatg
     5281 atgagtcagc ccttattcgt tttgatatgt ctgagtacat ggaaaaattt gcagcctccc
     5341 gtcttaatgg ggctcctcct ggctatgttg gctatgatga gggaggagag ctaaccgaaa
     5401 aggttagaaa taagccttat gccgttcttc tttttgatga ggttgaaaag gctcacccag
     5461 acatctttaa tatcctgctg caggtccttg atgatggtat gttaacagat agtcgtggat
     5521 gtaaggttga tttttcaaac acgattatta tcatgacgag caacctagga gcaactgctc
     5581 taagagatga taagacggtt ggatttggcg ctaaagcgat cggtcatgac catcaagcaa
     5641 tggaaaagcg tattttagag gaattgaaaa aggcttatcg gcctgaattt atcaacagaa
     5701 ttgatgaaaa ggtggtcttc catagcctaa cacaggaaaa catgcgtgat gtggtgaaaa
     5761 ttatggttaa gccgctgatt gcagccttgg cagaaaagca tattagcctt aagttccagc
     5821 catcagctct caagtacttg tctgaagctg gttacgatgt tgaaatgggc gctcgcccac
     5881 ttcgtcgcac cttgcaaaca gaggttgagg acaggttagc agaattaatg ctgtcaggag
     5941 agttatcaag cggtcaaagc ctcaagattg gtgtatcacg tggaaaacta gcttttgata
     6001 tcgcttaatg catgactttg cttgatatta agctaagagc tttgagagag tctgagacaa
     6061 aaagtttctc aggctctttt tgtcgtatgg tgatgaagta ctagagtgag agtttaaagc
     6121 gtagcagaca gataggattt aattttaatc gaatttagcg aaaaataggt attttgaaga
     6181 tttagctacc aatttagctg ccaaaatagt atctcatttg actatttttc ttagctgaga
     6241 tataatgaaa atagaaaaag gacagttgct caaaacaact acccaatgca gaaccgttta
     6301 agacggtagc ttgtttttag ttaaaaaata accgttactc gctaaagtta gacggttatt
     6361 ttttattgct catttttacg ataataacaa ctaagccaat gagtgaaagt agaaaactac
     6421 cgaacccaag catgagttgc attgcctcgt aaacggacaa tattcgctcc tttctctttg
     6481 gattttagca cttacagtca taagcaccac cacctttcag aaattagagc caccgcctta
     6541 acttttctgc agaaaccatt ataccatagt catacgaaat agctgtctga tgttgaaaat
     6601 tcagatggct tttttgtgtc ctttgcttgc agggaagaaa tataccctaa aatcgttttt
     6661 aagcgattgt ttgttgagat ggtatatttt ttatcgaata cgacataaaa attgaatatg
     6721 gttattctat gacttctgat ttattgtata ctattattag aaattgaaag gagaactttc
     6781 atgaaaaagt cgaccaaagc ttttattgct ttaatgattc taataggagg gctgcttatg
     6841 gtttttagtt tgaatggcaa aagaacagag gaacaacaaa aaaaggattt agaaactagt
     6901 attgctaaac tgctggttca tgactatgaa gatgtcaaag aagttaagtt tacaggctgg
     6961 ggacgttctc gggaaacagg ttcgtgggga acgatagtag ttataaatgg agaaaatgaa
     7021 ataggctttt cgtttgatgg tttgtcagga ttagcggata ttagtgggcg ctcttatcat
     7081 ccagatactt ttaagttagt tgagaaaaat agtctggaag aaatggggcc tgtgaaatat
     7141 agaattaaag acattgaaaa agtttcttta gagggagtgt caattacgta ttctcgtgag
     7201 aaaaggagtt aatatgatga tatccgatag tagttataag aagttgtcag aacaggtcta
     7261 taatgtcgaa cctagtaaag ctaagtcaaa tgatgcccct attgttttaa agggaaatcg
     7321 tcttatcgat gataagacgg gtaagcaata ccgagtcctc ttagttcagg ataataacaa
     7381 cgatgcccat aaaatcaatg acaacggtat gcaagcaatg gctgtagccc ctattgttca
     7441 aggtgatgtc gatacctccc aggttgtgat tgcctatgca gggacaaatg ctgcggattc
     7501 cagagatctt gatacggatt ggcagctgct cattcggggc aatcaagatg atttagtcag
     7561 cggcaatctt gatggcggca attttgttat tgccgaaaac caattacgat ctgctcaaaa
     7621 gttttatcaa caagtcaaaa gaaagtaccc tcattctgcc ttaacaacca caggtcactc
     7681 tctcggagct tatctagcac taatagt
//
LOCUS       DARYUW010000075         7706 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYUW010000075 DARYUW010000000
VERSION     DARYUW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7706
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(65..268)
                     /locus_tag="TVW11_001767"
     CDS             complement(65..268)
                     /locus_tag="TVW11_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1365841.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(285..542)
                     /locus_tag="TVW11_001768"
     CDS             complement(285..542)
                     /locus_tag="TVW11_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1365842.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(863..2230)
                     /gene="rlmD"
                     /locus_tag="TVW11_001769"
     CDS             complement(863..2230)
                     /gene="rlmD"
                     /locus_tag="TVW11_001769"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1365843.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(2227..3195)
                     /locus_tag="TVW11_001770"
     CDS             complement(2227..3195)
                     /locus_tag="TVW11_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1365844.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            3259..4035
                     /gene="recX"
                     /locus_tag="TVW11_001771"
     CDS             3259..4035
                     /gene="recX"
                     /locus_tag="TVW11_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1365845.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            4268..4801
                     /locus_tag="TVW11_001772"
     CDS             4268..4801
                     /locus_tag="TVW11_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1365846.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            5051..5362
                     /locus_tag="TVW11_001773"
     CDS             5051..5362
                     /locus_tag="TVW11_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1365847.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
     gene            6503..7706
                     /locus_tag="TVW11_001774"
                     /pseudo
     CDS             6503..7706
                     /locus_tag="TVW11_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT         2422 a         1781 c         1312 g         2191 t
ORIGIN      
        1 tttaacaaca ccaaatatca atagtataat cggaactaaa actaatacta ctaataatat
       61 tgttttataa tccattgata atggcctgtc ctgcaccaac aatgcatcct attcctgcac
      121 ccaatacata caatggacca gagaaagcac ctgtaacgat tgctccacct gcacaatgcc
      181 ctgcaacaga gccccaatta attttaccgc catttacact tgccaaatca agctcatata
      241 acatctgaaa atcttcgtac tgcttcatgg tatatactcc tttcttagtt aaatctatta
      301 cctatcattc cacccatgca tgcaaaacct cccccaattg caccaacatg tgcaccaaca
      361 aatgcacctg gaagtacgcc aatccctcct gctggggcac cccacaaagc cccacttcca
      421 gctcctatta acatatatcc tcccatgtct ttaagacagt ccttaccaga atatccacct
      481 tcaacagttg caagagcctc tatattcata acatcaaatt gattaatcgt ttctgtattc
      541 attttgaata cctccataac atattttttc tttatgtcgc gatcacgatt taagtatagc
      601 attctagtat catatttttt ctaaaagtct taaacggtcg ttttttcatc gtaaacggtc
      661 attttcaatc gttttcaacc gttcaagaca aaattaacta ccattcagga ttttcattgg
      721 ataaatagct attttttggc tctttgccaa cccactaaag ctattaataa aaaaataaga
      781 cagtagtcac atttaggcta ctgtctcttt tatctaaagc cttgatcggt aagaaaagag
      841 ccagtctttt ccaactaatc gattattgtt gtggtttttg tcgcttttgt agcttcacta
      901 cagcctcggt ccttgctgtg tgtggaaaca tgtcaacaga ttgaatatat atcacatcat
      961 agacctgaac caagggtacc agatcacgag ccaaggttga ggtattacag gagacataaa
     1021 ccattttagc tggctgatag tgtaaaatcg tttgtaatag cttgtcatct agtcctgttc
     1081 gaggtggatc tacaatcaag gcatcagctc ggtagccttc agcgtaccag cttgggatca
     1141 gttcctctgc cttgccagtc tcataataag cattgtcaaa gcccaatgcc tgcgcatttt
     1201 tcctagcatc agcaattgcc tctggaataa tatccatacc acgaacagat cttactttgt
     1261 ttgcaactgc cagaccaatt gagccaacac cgcaataagc atcaataata tgctcctcag
     1321 ctgtgggctc aagcgcctga accacttgac tatataaaac ctctgtctgt gtgggattaa
     1381 gctgataaaa ggctcttggc gacagggcaa agctatggct caaaacctcc tcttgaatgg
     1441 tctcctgacc ccagagaatc tcagttttgg cgccataaat atcactcgtt tttgaagtat
     1501 tgatgtttaa agcaacagtc ctgatttgtg gaaatgcagc agtcagctca gcaataagac
     1561 ctgccagcct cacctcttta ctgcttacaa aaatcaactg aacctgatca ctggcctgtg
     1621 ccctacgaac cataactgta cgaattccag ctactctgcg ttcattatag ataggaatcc
     1681 tataccgatc aagcagctga gtcacatgat taacaatcgc ctgtgttagc tgatcctgaa
     1741 ccagacaatc atcaatggca accaagcaat ggctcccttc tgaaaataag cctgccttga
     1801 cggagccacc aaacgaacgc gtctgaaact gtaattttgc tcggtaatgc tgcggctctg
     1861 ccattcctaa ggtatgacga atctcaaact cttcataccc cttaggctta aactttttta
     1921 aggcctgccg aatgatgtca tccttaaagt agagctgctt aggataggcc agatgcatga
     1981 tttgacagcc tccacaggtc tcataaatgg aacaggccgg cttcacccgg tttttagaag
     2041 ccttattaat caccaagagc cttgcctcag caaaattgcg cttaacagca gtcacttgac
     2101 aaaaaacctc ttctcccttc aaggctccgg gaacaaagac caaggtcttt ttataaaaac
     2161 caattccctc accattaatc cccattcgct taatcttaag cggtattttt tgctttattt
     2221 tgacattcat tcctgactaa atattactcc taatcgctta agccttgcta tcatctgctt
     2281 gccaacacct ggaatatcaa gaagctcttg agttgtccag gccgaaaaat cctccagagt
     2341 atgaatccca tactgattaa acaaattgac cttacttaaa ggaagatcaa gctcctctag
     2401 aaatgttagc tcgccttcag ccccttcaaa aaattcctga acataatgct gcaggtaata
     2461 ttgtgcagtc atcaatagcg gtaggatatt aaaaaaggca aggtaaatac ttgataagct
     2521 gtttggctcg tagctctcca gggcaccagc agctaaaata tcatctatcg gaaaggcttt
     2581 ctgtctgaca attgccacaa agtctggcac cgtctcagca aggttagcca aaatatcatc
     2641 agctagctct tctctttcag ctaatagcgc tccaaccatc aaaggaacct ccatcaacag
     2701 atctcctcta tgataatcct tactgtcata aaaagcctct gccatcgtaa aatcagactt
     2761 taacacataa agagctaaga tttcatacct tgtccctaag tgatcccctt catcgtattg
     2821 atgaatttct aagaggtgat gtaaagcttt ttcataaaga ccattttgct tatacagcat
     2881 cgccagctca aatttttgag acaagtaagg tctctcttca agattcaccc atcccatagg
     2941 cttagaagca agccaggcct gatgctgaca gtcttcatca aaggccaaat acttgattaa
     3001 gtcataggct ctatctcctg caaagtgctc caagtccgac aacaactggt tatccatgct
     3061 gtttaaaaga gcctctaagt catcactgaa aaactctgtc tcatgtccaa agagcatatc
     3121 atcttctgca tcagcttggc gatagtgctg taagctaaca accttatctc tatctttttt
     3181 atctttttct gtcataatgc cctttcaatc tattgaccat ttatactctt attttaccat
     3241 ttttgttata atgagggtat gaaaatcagt caaattgaaa agaaaaagca tttatacctc
     3301 attaagctag acaatggtga tagcctaacg gtcacagaag atacgattgt cacatttatg
     3361 ctaagtaagc acatggtcat agacagccaa caatgggagg acatcaaaag cttcgcacaa
     3421 ttctcatatg gtaaaagcaa ggccttaggt tttattgcct tccaacaaag gagccaaaag
     3481 caagtccaag attacctgct aaagcatcag attagtcctg atctcattcc aagcattatt
     3541 gatagcctaa aacaaggcaa atggattgat gatcagcaat acgttgacac ctatatacgc
     3601 caaaatagcc ttactggaga caagggacca ttacttctca agcaaaagct aatgctcaag
     3661 ggaatagcct cacaactcat tgagcctgtc ctagcacaga ctgatttttc ctctatagca
     3721 caaaaggctg ctgaaaaaat ctaccagaaa tatcaacaca aattgccaag taaggccttg
     3781 accgataaaa tcatacaagg acttcttaac aagggctttt cctatgacct tgccaaaggc
     3841 attgtcagtc aactaagcct tgagcaggat agtcagcaca tcgaagacct gcttgatcag
     3901 gaattcgaca agctattacg aaaatacagt cgtcgctatg atggctatca gttgaagcaa
     3961 aagctttacc aagcccttta ccgcaagggc tatgacagtg atgatattac cactaagcta
     4021 aatgactatt tctaattcta ccaaggctgc tgcaccgatt tgacgcaaaa gcttttagtc
     4081 agcaacaaag tagtcctatt atgatcctgt agctttgata atggtttagc tagctcctca
     4141 actgaacatc agatttctaa aaacttcttt aagcatttgt cagatcatat tgtccaaaac
     4201 agtgatttat tttctcaatt atggtaaact atagaggata agtttaattg tagaaagttg
     4261 gtaaggcatg aaattaccta aagaaggcga ctttattaca attcaaagtt ataagcatga
     4321 tggtagattg caccgaacct ggcgcgatac tatggtacta aaaacaactg aaaatgctct
     4381 gattggagtt aatgatcaca cacttgttac tgaaagcgac ggcaggcgat gggtgacacg
     4441 agagcctgcg attgtttatt ttcataaaaa atactggttc aatattatag caatgattcg
     4501 agataatggt gtttcctatt attgcaacct tgcaagtcca tacctgatgg acgcagaagc
     4561 gctcaagtat attgactatg atcttgatgt caaagtcttt gcagatggtg aaaagagatt
     4621 gcttgatgta gacgaatatg aaatgcacaa gcaagaaatg cattattcac ctaatctgga
     4681 ttttatttta aaagagaatg tcaagctatt agtcgactgg atcaataaag aaaaaggacc
     4741 attttcaaaa gcctatgtca gtatttggta caaacgttat cttgaactga agaatcgtta
     4801 gtcgttgtct agcactccac cgagggtgct ttatttaatc gctagtatag tatcacagct
     4861 gtaaactgga ctggcacttg caatctatca gcatttgttg tcaaattcat atcattaacc
     4921 actatagctt ggcacaagca cagacagcct ataacaccaa gtagcaatca gtatttatca
     4981 tcagctgcct agctagatca ggcattcaaa tgacctcatt ataacaccat aacaatagaa
     5041 aggattgaca atggcatttc aagcaacaaa aggacgatac gcaagctttg gcgttgcagt
     5101 cagccttcca cctgagctga ttgatacctt ctgggaaatc attgaccatt acctaaaagg
     5161 ggtgtttccc ctcaatactg ttctcacctt caggctaatt aaaaataaaa aaaacctttc
     5221 ttatgagtac attgatcaac aagctgggct tcggattgtt tttgactata acacaccatt
     5281 taacgccttt taccccaaaa cgctctatat cgtaaaccag caaggaattg aaacgatttt
     5341 attgcctcac gagatgtatt gataagacct cggacatcag ctataaagtc cttaccattc
     5401 agttgtagct catcacatct gctacaagca ccaacatgag ataatcttgt gtctttatcc
     5461 tagctctgaa tgctgtatag atattcagtc agccagatac atagcaataa actaagctca
     5521 tgccggtaga aatagtccta acatgagctt gacagttttt tcattctgta aatcattgct
     5581 aagcaaacac atcacctaag ccctatttcc tattctggga aatggaaatc ttgatagaac
     5641 atcccaatag tcccatcata ttgagctata tctatagggt ctgacatttt gatatgttat
     5701 catctcattt tacgacaatc actataggct ttatgacaat tggcatcatt gtcataacga
     5761 ttaaattcta tatgaccaaa tggctagtag gaagctaatt gctttgtgtt agcctcacat
     5821 aggatcttca cataccccgt aatcttaaaa gtagttttaa ctgcacaaaa cttatagaac
     5881 ctaaaaatca acaaacacac tttaaagtac aaaaactttg ccctccctca aaaagctcta
     5941 taatctctgt agtcggtaag cccactgtgg aaattatagt ttttttaatt gtacaaaaac
     6001 aagcccatat gacttatcat gaaatgcaat caaaccatca ttagaaagac tcataggaac
     6061 accttaagca ttactcagca tttaaaaaac aatatccaac cgttgactgt tctaaaagct
     6121 caccctcaca tcgttatcaa tcctaagctt gattattcag ttctcttatg ccctcactac
     6181 aaaggaaaca tgagcaaaca agacttccaa aaagcctcta aaatccctat cttcgattgc
     6241 caaagctttc caacactgct tcaactcaaa aaacactgct ttcagtggaa agccagttct
     6301 aaagtgagcc ttgctcaaac tccttttggt tttaacatca caaaaaagag caccaatctg
     6361 gtcctcttta gacgttagtt aggctcaata atttctgtag tgggtaagtc cactgcaggg
     6421 gttatagggc tttatgagta tcaaaaaagt cccatatgac ctataatgaa aagcgactaa
     6481 actatcattt agaaagactc atatggaaca atcacatgtt atcacacaac tactgggaat
     6541 taaagaccct catatcacat tctccaaaga aatacacgac atgaaaactc ataaggaatt
     6601 gaaagctgtc cttgactacg atgccccacc ttgccctaac tgccaaagtc agatgggcaa
     6661 gtacgacttc caacgggaat ccaaggtccc ttttctcgat tgcgcaggct acaagacttt
     6721 gattcgcctc aaaaagcgcc gtttcaaatg tcagttttgc ggaaaaatta ctgtcgctga
     6781 gacttctcta gtccctaaaa accatcaaat accaaccatc gtcaaacaga aggtggccca
     6841 gcttctcatc gagaaagtct ccatgaccgc tatcgctgat agactatcca tctccacctc
     6901 aaccgtcatg cgaaagctca acgagttcac gttcaagtct catttgactt atttacccga
     6961 acatatgtcc tgggatgaat atgcctttaa gaagggcaag atgagcttta ttgctcagga
     7021 ctttgacacc aacaacatca tcgctatttt ggatggacgg acgaaagctg tcattcgcaa
     7081 ccacttcctg agatatcctc ggcaggtcag aaacgacgtt aaactcatca ccatggatat
     7141 gtttaccccc tattacaacc tggctaagat gcttttccca aacgcttaga ttgtccttga
     7201 tcgtttccac attgtgcaac atttgggacg tgccatgaac cgtatccgta ctcaaatcat
     7261 gaactctttt gatcgaaaat cccacgaata caaggctttg aaacgttact ggaagctgat
     7321 tcaacaagat agtagcaaac ttagtgacaa gcgtttttac cgcccgactt ttcgcatgca
     7381 tttgacaaac aaggaggtgg tcgagcgtct tttgagctac tctgacgagc ttagaaagca
     7441 ttatgacctt tatcagcttc tgctttttca cttccaggaa aagcaagctg accacttttt
     7501 cggcctgatt gaggagcaga tagacagtag caatcctctc tttcagaccg ttttcaagac
     7561 ctttttgaaa gacagagaca agattgagaa cgcactggat ttgccttatt ctaacgctaa
     7621 actggaggct accaataatc tcatcaaagt catcaagcgc aatgcttttg gatttcggaa
     7681 ctttgaaaac tttaaaagac ggattt
//
LOCUS       DARYUW010000076         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYUW010000076 DARYUW010000000
VERSION     DARYUW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            436..975
                     /locus_tag="TVW11_001775"
     CDS             436..975
                     /locus_tag="TVW11_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365848.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TVW11_001776"
     CDS             972..2087
                     /locus_tag="TVW11_001776"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1365849.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TVW11_001777"
     CDS             2077..3339
                     /locus_tag="TVW11_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1365850.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TVW11_001778"
     CDS             3385..4404
                     /locus_tag="TVW11_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1365851.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TVW11_001779"
     CDS             4603..5313
                     /locus_tag="TVW11_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365852.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TVW11_001780"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TVW11_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1365853.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TVW11_001781"
     CDS             6662..7471
                     /locus_tag="TVW11_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1365854.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2018 a         1599 c         1799 g         2079 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaagg tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt actggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYUW010000077         7319 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYUW010000077 DARYUW010000000
VERSION     DARYUW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7319
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(139..633)
                     /locus_tag="TVW11_001782"
     CDS             complement(139..633)
                     /locus_tag="TVW11_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1365855.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(626..1909)
                     /gene="aroA"
                     /locus_tag="TVW11_001783"
     CDS             complement(626..1909)
                     /gene="aroA"
                     /locus_tag="TVW11_001783"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1365856.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(2042..2980)
                     /locus_tag="TVW11_001784"
     CDS             complement(2042..2980)
                     /locus_tag="TVW11_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1365857.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(2982..3842)
                     /locus_tag="TVW11_001785"
     CDS             complement(2982..3842)
                     /locus_tag="TVW11_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1365858.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(3859..5142)
                     /locus_tag="TVW11_001786"
     CDS             complement(3859..5142)
                     /locus_tag="TVW11_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1365859.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(5135..5689)
                     /locus_tag="TVW11_001787"
     CDS             complement(5135..5689)
                     /locus_tag="TVW11_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1365860.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(5983..7272)
                     /locus_tag="TVW11_001788"
     CDS             complement(5983..7272)
                     /locus_tag="TVW11_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1365861.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         2073 a         1804 c         1351 g         2091 t
ORIGIN      
        1 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
       61 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
      121 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
      181 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
      241 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
      301 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
      361 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
      421 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
      481 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
      541 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
      601 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
      661 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
      721 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
      781 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
      841 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
      901 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
      961 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
     1021 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
     1081 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
     1141 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
     1201 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
     1261 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
     1321 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
     1381 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
     1441 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
     1501 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
     1561 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
     1621 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
     1681 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
     1741 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
     1801 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
     1861 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
     1921 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
     1981 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
     2041 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
     2101 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
     2161 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
     2221 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
     2281 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
     2341 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
     2401 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
     2461 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
     2521 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
     2581 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
     2641 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
     2701 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
     2761 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
     2821 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
     2881 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
     2941 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
     3001 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
     3061 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
     3121 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
     3181 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
     3241 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
     3301 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
     3361 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
     3421 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
     3481 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
     3541 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
     3601 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
     3661 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
     3721 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
     3781 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
     3841 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
     3901 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
     3961 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
     4021 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
     4081 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
     4141 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
     4201 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
     4261 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
     4321 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
     4381 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
     4441 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
     4501 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
     4561 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
     4621 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
     4681 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
     4741 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
     4801 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
     4861 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
     4921 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
     4981 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
     5041 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
     5101 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
     5161 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
     5221 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
     5281 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
     5341 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
     5401 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
     5461 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
     5521 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
     5581 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
     5641 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
     5701 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
     5761 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
     5821 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
     5881 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
     5941 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
     6001 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
     6061 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
     6121 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
     6181 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
     6241 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
     6301 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
     6361 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
     6421 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
     6481 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
     6541 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
     6601 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
     6661 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
     6721 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
     6781 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
     6841 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
     6901 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
     6961 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
     7021 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
     7081 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
     7141 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
     7201 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
     7261 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaacta
//
LOCUS       DARYUW010000078         7210 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYUW010000078 DARYUW010000000
VERSION     DARYUW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7210
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..245
                     /locus_tag="TVW11_001789"
     CDS             <1..245
                     /locus_tag="TVW11_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365862.1"
                     /translation="KNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDTEKIE
                     AVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            238..651
                     /locus_tag="TVW11_001790"
     CDS             238..651
                     /locus_tag="TVW11_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365863.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            914..1306
                     /locus_tag="TVW11_001791"
     CDS             914..1306
                     /locus_tag="TVW11_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1365864.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            1307..1630
                     /locus_tag="TVW11_001792"
     CDS             1307..1630
                     /locus_tag="TVW11_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365865.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            1943..2413
                     /locus_tag="TVW11_001793"
     CDS             1943..2413
                     /locus_tag="TVW11_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1365866.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            2397..3490
                     /locus_tag="TVW11_001794"
                     /pseudo
     CDS             2397..3490
                     /locus_tag="TVW11_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(3784..6930)
                     /locus_tag="TVW11_001795"
     CDS             complement(3784..6930)
                     /locus_tag="TVW11_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365867.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         2141 a         1285 c         1514 g         2270 t
ORIGIN      
        1 gtaagaatag acaatttgaa tatggagaag gaggacaatt gatgatttca cttcctaatc
       61 caaagtatcc tgatagatcc tttcttgata gggtaacctt agaaagtctt ttaacagaca
      121 ccgaaaaaat agaagcagtt gactatgctt ttggaagata cgagcatcgt ctcgaaatag
      181 cgttggccat tctaaaagat tatttagatt cagacgaagc aaaggtttta ttgaaaaatg
      241 agtgagcaat atttatcaat aaaagaaagc ttaggttata agaacgttaa acaggcttta
      301 tggactattt tttcagccaa ccttgatgaa atttctatac atgaaggaga agatgagaat
      361 tttaactttg tctttacata taaaaattgt gaaatgatga tgggaattta tgatactggt
      421 aagaatattc aattccaagc tggagaaggt ggtttattca gtgtaagttt acctaatcct
      481 aaatatccgg agcagtcatt tcaaaaaatt gtatcacttt cttatttaat ttctgataaa
      541 aatgtaagtg aaaatataag atggtgctta ggactggatc tgaaatctgt tgaatatgtt
      601 atgcgtgttt tgaaggatta tctggatcaa aaatgtgaag aggaacaata attctaatca
      661 cttctggagg gcatatagat gagtgaagaa cagtatttac caataccttc gaagagaata
      721 ccagttaaag ggaaggtatt ttgcagaaag aatcaccatg ccagatggaa aatatgctta
      781 tctgtccaat gacattgata aagctaccgg aacaccaatt cctgtccgat atagaaatta
      841 ccttaaggct gatggttcta ttaattggcc aaactataat ggctttagtc ttgatgtaaa
      901 gggaaggcct atcatgactc cagctttcct aaaaacaggt gatttacttg atagatatgg
      961 agaatctgga ggaacattca caagtccaat cgttgaccgt aaggttatac catttaacaa
     1021 gcgaggctta ccatacccag aggactatca aaattatcat caatataagg ttcttaagga
     1081 tattaatatg gaaaatgttg aaaagggtta ccataattta tctgatagta gaaaaaaaga
     1141 gttaaatcta ttaatgaata gatttgattt ttcactggta gacatagcaa ctccacaaaa
     1201 aggaatgatt gatcttgtct ttggctctgg tggaggtatc caaataaagt taggaacttc
     1261 tgtaagttgg tatgaaaaat tgggtttaat taaggagata aagtagatga aaaatttaga
     1321 tcatcaaaag gcagaactat tagaagcagt ccatcaatta ggttatgata gtctaaggta
     1381 ttccattttt tctaaagaga gaccaggaga atgggaaact gtcattgaat atgataatag
     1441 tcaaggctta tatgttgtgt atgcaactat ggatagagct agttataata agaaattaac
     1501 atttgaaaca tttcaagagg ctaaagaaaa atttcttgaa aaacttcggt tagatatcca
     1561 aatcaacagg tactatgtgg aagagggcat gcctgtaaat tacgattctc ctttgtggtc
     1621 aaaaaattaa tacaagtaaa ggagaatata catggcatgt agtcaattag agtgggaaga
     1681 taaatgaaat aatggtccta ggaaatgtcc cgactggaaa ctatcttatg aactctttta
     1741 tggaaaagtg ttgcacttaa tttgaatttt gtcatataaa aaagccctat aatctccatg
     1801 gtggacttac ccactacaga aatgatagag ctaaaaatct ccatttgggg atttttttgt
     1861 aaccaaatga agcagtcgtt cgttatatag gtgaagaagg gaggggagaa ttatcaggct
     1921 agatgcttat gaaagagagc tagtggctta ttctaaggaa attattgcct acctagtgag
     1981 atcaggtgtt gctaaggagc tagcgcgtga tattagtcaa gacgttttgt taaaaatgct
     2041 tgagagtgac cttgctctgc ctcctgaaaa aatacgtgcc tggatgtatc gggttgctgt
     2101 tagaaaatac attgaccgat ataggcggga taaggcttac ttggatattc tccaaaggga
     2161 tttttttcat caagaaaggg ttgttgaatt tgaccacccc aattatgagc cgctttatac
     2221 agcagtcaat gaattgccag aaaaataccg ctgggtcttg tcgttttatt actttcagga
     2281 cctatcagtc aaggaaatgg cgtctctgct ccattggtca gttagcagcg tcaaggtcaa
     2341 cttgatgcgg ggaagacgat gccttaaaga aaaactaaag aaagcaggtt atacctatga
     2401 cgatttcaac tgattttgaa gccattgcta agcgccataa aaggaggctg acccttaaat
     2461 atgtagtgct gagtgctggc ttagccttag tagctcttgt actgggctat atgggattaa
     2521 atcgattgac aagcatgaac ggtcagtatt taatggctta ttacaacaat cgtatacaaa
     2581 ttgcttatcc caatattgat gttaatagct tcttttacaa tgccaattcg cagtttactg
     2641 gtgagcttca ttctgagcgg accaaggata ttgctgggat ttcggtaccg tttgagccct
     2701 atagagctcc ttattccttg cctttaccca gagagagatg gactatacca atgaatacct
     2761 tgtttcaggt gatgatggac ggtcaaccta cacaagaggt acacattata aaatgcctcg
     2821 cttcttcaac actaaggcca agatcacaga aagcaactat gacaagccaa cgcaggacct
     2881 agactttatt gctgacatgt caggacaggc gattgaggta gccattacct ttgataagcc
     2941 ttatttatta tcggacatag tcaagctggt tccagaccag ctaaagctga attggatctg
     3001 gattggcaca gaaagcagct atgacacctc agggcttttc cctgctaatt tatatggctt
     3061 taagccaaac tggaaggcta atatgacgta caaggagcaa aagcagttag ataaaaaaat
     3121 aaacgatatc ctaaaaaagg acagcgaggc tgatttgtct aagcttaatg ctgcttacga
     3181 taagccagtc agtccaacgg tggctctgca aaattcctat gataccttca ggcactatct
     3241 acaagaggca gctgacaatc attggattaa tagtacctat ggcggcgcta atggatctca
     3301 tttaagtgag caggaggatg tggccttatt tctaaaaaac aatcgcaatg tcaaaacagc
     3361 taagtttgct ggcattattt taaccggcaa ggctgagcag tttgcctcct taaaaacagc
     3421 tgattggatt tatgcctcaa atattggtca gtctgttgcc attcagccct atcatcagct
     3481 aaccaagtaa ataaaaagct tgtgctgcta atcaagcgca tcaggcaaag gataaaaagc
     3541 ctaaaagaga ttagattaag taaatcgatg cttaaaaaag ctccagctta ggtcaaaaga
     3601 cgtcaaaagg ctcttggagg tcagtgtttg atcactgctt ctggggcttt ttgctttgct
     3661 gcaatcaaaa aagcttgaag cagctctctc aattgagcat gtccttcaag ctgagactct
     3721 tatattttat agtatttgta agtatagttt tagctagcct tcttttaagc ccaagggctt
     3781 agcttactgt ttagtatctt tttctaaatt attgataata actggataat ccttcaatgc
     3841 agacttcatg tcatttagag tgctttgata tgctgtttgg tctgaggcta ccaatgctag
     3901 cttgtcattc catgctttat agtttaatgg ctctgccttt agagcagcat ctaaatgatt
     3961 aagcttagtc tccttgtcag tagctgcttc agccttatat cgttcatatt ctgaggcatt
     4021 ataagcgtct atattaagag agtagacgtt atgaatttgg acataaggaa gtgttgtgtt
     4081 gtagttacca cagcctgtcc agcctgagac atcatagccg agctgatagg tatggtcagc
     4141 atttaagtag atataagcac agtgacctgg ttgtccaata ggaaaggctg gtacaccata
     4201 agcctgtgct agcacactac ttaatttaga catagcaccg cagacaccac catatttgat
     4261 gacttccttg atggttggat ttggtccgta aaagccagag ctttggacgc tcacacctgt
     4321 ttctgggttg gtcatgacat agctgatcag tgaatagccc ttagtaatat cattacggtt
     4381 aatcatagca ggcttattgg tttcaacgta ttgtcttaac catttcatgt cctcatcagt
     4441 aattttagca ttgacgacat ttcggatttg ctcaacagtt aagctgtaaa aatcttcaaa
     4501 taggatattg ccctgctcag cctctgcaaa ggttgcaaat ctttcaagtg gatcaatctt
     4561 gcggctttca ttgtaccaag cacctacagg cttgttaaat tccaaggcaa ccgcaatggc
     4621 cattttgagc tgaatacctt gatgtgaggt ttcgtattta tcccaaatct taaaccacaa
     4681 ttccaatgct tctagctcat tggtgaggtt ataggtgttt ttgaattggt atgatgacat
     4741 gccaccctgt gctgcagaat gggcatagcc tgcaccaaga tataattgca ttgcttcatt
     4801 atctttgagc aaccaatcaa taaaggcttt atgcttgtcg tcttgcttct tgaagtcctc
     4861 gattttttcc ttggttagtc ttttttcaac ggcttgtacg agtgtattag tagctttagc
     4921 ctctagtgca aatacagaag ccaaaccacc cttggtgatt cgaatctctg ccttattttt
     4981 agggaggcta agagaaacag ccttgttttc ttcatcatag gctttgactc tagtatggtg
     5041 ctcactacca gttaggcgga tcttgtagcc caccttgaag ggaatagtct ctgttttggc
     5101 tgttagagct tggtttccaa taaagtcttg tgtgtagaca accttgtctt ttaggtctaa
     5161 gacctcaagc ttttcgtaag tcccactgaa gtaaacatgt ggcttagcct ttttggtttt
     5221 gagagttaag gtagaggcat tgtagtcaac ctttaaggtt gcgtattctg cattgcctaa
     5281 gccaaggaag cgcagcgttc tattactatc atcaatacgc tcaagctgcc cgtttctcac
     5341 cacataagtg taagggttgg tattgttttg ctttagagcg tcattgtggt tagtgtagaa
     5401 gcggttaggc tcctgcttag tgatgactag gtaatagcct tccttgagag taaggctttc
     5461 tgttttagct gtttgggaaa cattacccac gtattcctta gcataaacgg tttctttttt
     5521 ctcattgaga atggttaggg tagcgtaatt gttagcgatg taagagtgag gctgtccttt
     5581 tttagtgact aagcttgcag tgtaactgcc gtcagcatag aagtagagct gagcaaatat
     5641 accatttcct agcccttgta gagtaaattg ctgtagcagg ctagctgcct tatcaagtaa
     5701 acttaggatt tgctcttttt caggctctgt tgagtcagtc gcctttttcc taagagcatc
     5761 tattttttct tgtgtgacac cacttgctag cttacttgta gactcatctg taaatagagt
     5821 cagtacctca gactcaagct ctgagcctgt tttagacctc attagctcta gtgagtggtc
     5881 aagaagcttt aaggttgctt gatttttaga gagtgttaat ggcgcttcta ccgcataatc
     5941 atcgtagaat ttcactctgg tatggtgctc actacctgtc aagcggatct tgtagcctac
     6001 tttaaaagga atagtctctg ttttagcttc gaggacttga gttccaataa agtcctttgt
     6061 gtagattact tgattttctg tatccagcac ctcaagcttt tcataagatc cactgaagta
     6121 aacatgtggc ttggtctgct tggttttgag ggttagggta gaggcattgt aatcaaccct
     6181 taaggttgca tactctgcat tgcctaagcc aaggaagcgc agcgttctat tactatcatc
     6241 aatacgctca agctgcccat ctctcaccac ataagtataa gggttggtat tgttttgctt
     6301 tagagcgtca ttatggttag tgtagaagcg gttaggctcc tgtttattga tgatgaggta
     6361 atagccttct tttagctcaa gctcttctgt ttgtgctacc tgagaaacat tgccggcgta
     6421 ttcttttgaa tagacggttt ccttcttgtt attaagaatg gttatcgtag cgtaattagt
     6481 agagaaataa gagtgaggct ggcccctttt agtgaccaaa cttgcagtgt agctgccatc
     6541 agcatagaag taaagttgag caaagacacc attgcctaac ccttgtaggg taaactgctg
     6601 taataggcta gctgccttat ctagtagacc taggatttgc tctttttcag gctctgttga
     6661 gtcagtcgcc ttttgcttta aggtatctat tttttcttgt gtgacaccac ttgccagctt
     6721 actgcaggag ttatctgtaa ataaggcttg ggtatcagtc atcagttgtg atagcttagc
     6781 ctcggcagaa ggagcagctg tatcacctgc attaactgta gcggctattc catcagaagt
     6841 atcagtagtt gcataaacaa ttgctggaga gagctgatgt aatgttaata ttccaacaca
     6901 tgctagtgct attattttct ttagtttcat cgttataaag tccttttaca ataaaataaa
     6961 gtgattcaaa actctgggaa aagaatagct agccttaaaa ctatactcgc aaatactata
     7021 aaatagaaag actatttacc ctccttagct cttgatgctg tggtgatgat attgttacgg
     7081 tgctaaaaat cctatccctc ctttttgact attttgtctc tcttattcca taatattaaa
     7141 aaatcagaat atgtcaatat atattttctt taatcctaga aatgataaat aggtttggaa
     7201 aattcttaat
//
LOCUS       DARYUW010000079         6866 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYUW010000079 DARYUW010000000
VERSION     DARYUW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6866
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            116..328
                     /locus_tag="TVW11_001796"
     CDS             116..328
                     /locus_tag="TVW11_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1365868.1"
                     /translation="MSQQHRKWSALVEQRLKEKDWTKGDLALAVGLRSSGTITDLLAK
                     GKGSVDLKVRVSKILGIREPWELFER"
     gene            401..652
                     /locus_tag="TVW11_001797"
     CDS             401..652
                     /locus_tag="TVW11_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365869.1"
                     /translation="MDNILMSLSDWIKEIIEKTVNRLVQIKLDEANAELLTREKVADR
                     LNMSPATFDKYYRYDKNFPSELPGVRWKKAEIIAWLNNK"
     gene            928..1269
                     /locus_tag="TVW11_001798"
     CDS             928..1269
                     /locus_tag="TVW11_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365870.1"
                     /translation="MTQAERIREFYKENPTASYDEVAEAIGTTNSNVRANIAKDIKAG
                     RCVRLEDKSLDYSAHFGATEALADLVDWKNDTRREWVEMLTRAAEKETDSNTMRLLIK
                     EANKLMKEVTK"
     gene            1269..1751
                     /locus_tag="TVW11_001799"
     CDS             1269..1751
                     /locus_tag="TVW11_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEL1365871.1"
                     /translation="MAKLYELVGEYRDLYELNLDDETLKDTLDSIDWADRLSEKVEGY
                     AQVIETALAEAKMFEEAEKKFKAKKEAAKKKAAWLQGNVFDAMKLTNQTEIKSGIFTV
                     RIKQNPESVKVDEELLPKKYFNKKITVAPDKTTLKELLKSGKKIKGAELIRTEKLVIK
                     "
     gene            1748..2221
                     /locus_tag="TVW11_001800"
     CDS             1748..2221
                     /locus_tag="TVW11_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365872.1"
                     /translation="MMILAIDPSSNRIETSTTGIVLLDNARLVDYWVVPFGAENFKKW
                     FKDIGRTLEFDTVVVEKFEVRDNDYSRDNSVVETISAIELCYPDLVLQRNAGYQTDIP
                     NGLLKALGLWSFDKSHHNDVRAAARLGLFWAQRNDIEEVIVDIGNRITQMASGSS"
     gene            2181..3356
                     /locus_tag="TVW11_001801"
     CDS             2181..3356
                     /locus_tag="TVW11_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365873.1"
                     /translation="MAIELRKWQAEAVKRSDRDCPGIFLEAYGGRGKTICAFEIAKHK
                     EAKKVLVINNRLAILNGWNNTHQDLGYVNDFELEIMTDRRLQNRLASGESIECDVFVI
                     DEWQNMSSDANVKAYKKVKRGYTVGLSATPIRKKGQNFYPLEKTIFGMAEPNQRENWQ
                     LAHGKMKYSKFSYSKQEWDDFRNYESYVANLPNFFRWEDVEAIEEAEENNGFEVIFEP
                     VWCPPANPKELEQFRSLNIVGKDGKFAMAKQTFGRKIFERYLIQTGFEIDFPKLKAIN
                     ADTPMLIQLDLLLASHTEMLIVSKSKQIVEVIRERHPEIGIWTGDKKDALEQTNVVAT
                     TQVLGVGVDGLQYKFKTIVVLDPVNPSDGDYDDYRQLLWRVTGSRQQHDVRVIEFYF"
     gene            3366..4076
                     /locus_tag="TVW11_001802"
     CDS             3366..4076
                     /locus_tag="TVW11_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEL1365874.1"
                     /translation="MAEHKESGIFIVLRCIQADLIAPKGQYNSFGKYAYRSAEDILEA
                     LKPLLKKYDASIVLSDEIVQVGERYYVEATATLYAMGECVGNKAYAREDETKKGMDGA
                     QITGAASSYARKYALNGLLAIDDNNDADTDAYHNQNNQSAGKTQKTNQKQASQQESTA
                     KAPAKNNGSKTITGAQAKAIRTELKNMAEATGSPAAAIGNWFIGKMGVDKPENIPAER
                     LKEAQQIIADAKKVKGIE"
     gene            4077..4469
                     /gene="ssb"
                     /locus_tag="TVW11_001803"
     CDS             4077..4469
                     /gene="ssb"
                     /locus_tag="TVW11_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1365875.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGVLIGITGRIQTRNYENQQGQRVYVTEVVADNFKM
                     LEYRQQQQQEDSFDNNNPMDIQADDLPF"
     gene            4483..5310
                     /locus_tag="TVW11_001804"
     CDS             4483..5310
                     /locus_tag="TVW11_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEL1365876.1"
                     /translation="MGMKEYALAYQKKGFSVLPISPTGKKPMIAFADKPPMTAQEIED
                     FWTQYPDSNIAVRTDKFFVIDIDLHGKANGFESLANWEHLDLITPTLQAKTASGGKHI
                     FYFKHPDVSMTQMIGFLPGVDVKAHLNNYVLVAPSKTPKGVYAWDKDKSKEDGTMVTA
                     SRKLVMAIKQEYNKKNPGSDLDNIYYQISKGAGKRNRTTELFEMIVLGFGDQGGRNDT
                     LARFVGGLLSRSVDPECILRLAETANNNSVEPLGKREMRRTIESMIKKHMRGGGHNR"
     gene            5294..6694
                     /locus_tag="TVW11_001805"
     CDS             5294..6694
                     /locus_tag="TVW11_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1365877.1"
                     /translation="MATIGEIVNISIKQFSRRKKKILSEEGEQIEVESIVADSPRNVL
                     LAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFKT
                     VFKAGALRDGIEAFFAEKTYNPVQEYMEHVYESWDHRERLAQVFQTWLGAEDSIFVQR
                     IAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVAVEWYTDSAKDFMDKDN
                     YEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFVIARTS
                     NKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLTFDD
                     DFEDELAVYKERFTYKDEAESQIYDYLDMLVPDEWEEMSVVQQHQYTWAYFNNGSYRN
                     ESGFVYEGVKLQASVSAKQILKNVFDIDSARGERIARKIKLIMDNHQDWEYRIKKIKG
                     RTVRAYFKKNMQNEVM"
BASE COUNT         2271 a         1169 c         1675 g         1751 t
ORIGIN      
        1 agtaggaggt gagaatttgg ataatttaca aagacgttta gaacattttg taatcagagt
       61 atcgagacat tgcaacctca cgtttttatt ttaattatat cagaaaggag aataaatgag
      121 ccaacaacat cgaaaatggt cagctcttgt tgaacagcga ctaaaagaaa aagattggac
      181 caaaggcgac ttagcactag cggttggttt gcggagttcg ggaacaatca ctgacttact
      241 cgcgaagggt aaaggtagtg ttgatctaaa ggttagagtt tcaaaaatcc ttggaattcg
      301 tgaaccatgg gaattatttg aaaggtaaca aaaaagtccg acgggaatcg gactcaaaac
      361 aaaaatttac tacttagatt atatcacaaa ggagctaact atggacaata tcttaatgag
      421 tttgtccgac tggataaaag aaattattga aaaaacagtt aacagattag tccaaatcaa
      481 attagatgag gcaaatgccg aattattgac tagagaaaaa gtagcggaca ggcttaacat
      541 gagcccggct acttttgata agtactacag gtatgataaa aattttccaa gcgaattgcc
      601 aggcgttcgt tggaaaaaag ctgaaattat cgcctggcta aataacaaat aagacttttg
      661 gacgaggtct aatcacaagg gaagaaacac tggaaaacaa ttaggagtgt aattatgttt
      721 aataaaaaga aaaaattgca gaagtcattc aataatatta acaagcacat tgatagtctg
      781 acgctgtcag aacaagaaaa gcgtaatcta aaaggattgc tccgtaatgt caaaattaga
      841 acaagggtgg cgtgatgaat gcaattggta tgtatagcat tttagagcgg ctagaccggc
      901 ttgaaaaaat cgtatttgaa acagtagatg acacaggcgg aacgcattag ggaattttat
      961 aaggaaaatc ccactgccag ctatgatgag gtggcagaag ctatcggaac gactaatagc
     1021 aacgtcagag ctaatatagc caaggacatc aaggcaggca gatgtgtccg cctcgaagat
     1081 aaatcattgg actactcagc tcattttggg gcaacggaag ccctagctga tttagtagat
     1141 tggaaaaatg acactagacg ggaatgggtg gaaatgctga ctagagcagc agagaaagaa
     1201 acagatagca ataccatgcg attgcttatc aaggaagcta ataaactgat gaaagaggta
     1261 acgaaataat ggctaaatta tacgaactcg ttggggaata tcgggattta tacgagttaa
     1321 atcttgatga tgaaacctta aaagatacgc tagacagtat tgactgggca gacagattgt
     1381 cagaaaaagt tgaaggctat gcccaggtta tcgaaacagc acttgctgaa gcgaagatgt
     1441 ttgaagaggc tgaaaagaaa ttcaaagcca aaaaagaggc tgctaagaaa aaagccgcct
     1501 ggttgcaagg gaatgtcttc gatgccatga aattgaccaa ccaaacagaa attaagtcag
     1561 gaatttttac agtgcgaatt aagcagaatc ctgaatcggt aaaagttgat gaagagttac
     1621 tgccgaaaaa atacttcaac aaaaagatta cagtcgctcc ggacaagaca acgttaaaag
     1681 aactgctcaa atctggaaag aaaatcaagg gagcagaact aatacgtaca gaaaagttgg
     1741 tgattaaatg atgatactag caattgatcc aagtagtaat cgaattgaaa ctagtacaac
     1801 aggaatcgtc ttactagaca atgcaaggct agttgattat tgggtagttc catttggtgc
     1861 tgagaacttt aaaaagtggt tcaaagatat tggcagaact cttgagtttg ataccgtagt
     1921 ggttgaaaaa ttcgaagtta gagacaacga ttattccaga gataattcag tagtcgagac
     1981 tatatcagca atcgaattat gttatccgga tttagttctg cagagaaatg caggctatca
     2041 gacggatatt ccaaacggtt tgcttaaggc tcttggtttg tggtcttttg ataaaagcca
     2101 tcacaacgat gtgagggcag ctgcaaggtt gggattgttt tgggctcagc gcaacgacat
     2161 tgaggaggtg attgtggaca ttggcaatcg aattacgcaa atggcaagcg gaagcagtta
     2221 agcgtagcga ccgcgattgt cctggtatct ttttggaagc atacgggggt aggggtaaaa
     2281 ctatttgtgc ttttgaaatt gcaaagcata aagaagctaa gaaagtactt gttatcaata
     2341 accgattagc tatcctgaat ggttggaaca acacccatca agatttaggc tatgtaaatg
     2401 attttgagtt agaaatcatg acggatcgca gattgcagaa cagattagca agtggtgaat
     2461 ctatcgagtg tgatgtattt gtcatcgatg aatggcagaa tatgtcgagc gatgccaatg
     2521 tgaaagcata caagaaggtc aaacgcggct atacagtagg gctttctgca acgcctatca
     2581 ggaagaaagg gcagaatttc tacccgttag aaaaaacaat atttggaatg gctgagccta
     2641 atcaacgtga gaactggcaa ttagcccatg gtaagatgaa gtattccaag ttcagctatt
     2701 ctaaacaaga atgggatgac ttccgaaact atgaaagcta cgtggccaat ttaccaaatt
     2761 tcttccgttg ggaagatgtt gaggccattg aagaggcaga agaaaataac ggttttgagg
     2821 taatttttga accagtttgg tgcccacctg ctaatccgaa agagctggaa cagtttagaa
     2881 gtctaaacat cgttggtaaa gatggcaagt ttgcgatggc taagcaaact tttggtcgaa
     2941 agatttttga gaggtactta atccagacag ggtttgaaat tgactttccg aaattgaagg
     3001 cgatcaatgc agatacacct atgctaatac agcttgattt attgttggcc agtcatacag
     3061 aaatgctgat agtcagcaag tcgaagcaaa ttgtagaagt cattcgtgag cgtcaccctg
     3121 agattgggat ttggacggga gacaagaagg acgctctgga gcaaaccaat gtagtagcta
     3181 ccactcaagt acttggtgtc ggtgtggatg gcttgcagta taaatttaaa acgattgttg
     3241 tcctagatcc agtcaatcca tctgatggtg actacgacga ctaccgccag ctattatggc
     3301 gggtaacggg cagccgtcaa caacatgacg tgcgtgtcat tgaattttat ttttgaggag
     3361 acaaaatggc agaacataag gaatcgggta tctttattgt tttgcgttgc attcaggctg
     3421 acctaattgc tccaaaaggg cagtataact cttttggtaa gtatgcctat cgtagcgctg
     3481 aagatatcct ggaggctctc aagcctcttt tgaagaaata tgatgcctca atcgtactga
     3541 gcgacgaaat cgtccaggtt ggggagaggt actatgtaga ggctacagct accctttacg
     3601 caatgggtga atgtgtagga aacaaggctt acgctcgaga agacgagacc aaaaaaggta
     3661 tggacggggc acagattaca ggtgcagctt ctagctatgc tcgtaaatac gctttgaatg
     3721 ggcttttggc tattgatgac aataatgacg ctgatacaga tgcctatcat aatcagaata
     3781 atcaaagtgc tggtaaaact caaaagacta atcaaaaaca agcgagtcag caagagtcaa
     3841 cagcgaaagc tcctgctaaa aataatggtt ctaaaactat tactggagcg caagccaagg
     3901 ctatccgaac agaactcaaa aacatggcag aagctacagg aagtccagct gctgcaattg
     3961 gtaactggtt tatcggaaag atgggcgttg acaagccaga gaacattcct gcagagcgtt
     4021 tgaaagaggc acaacagatt atcgcagatg cgaaaaaagt gaaagggatt gaataaatga
     4081 ttaataatgt agtactagtt ggtcgtatga ccaaggacgc agagcttcga tacactccaa
     4141 gtcaggtggc agttgctacg tttacacttg ctgttaatcg cgcctttaag agccaaaatg
     4201 gtgagcgcga agcggatttc attaactgtg tgatctggcg tcagcaagct gaaaatttag
     4261 ctaactgggc gaaaaagggt gtcttgattg ggattacagg acgtattcag acccgtaact
     4321 acgaaaacca acaggggcag cgtgtgtatg taaccgaggt tgttgcagat aatttcaaaa
     4381 tgctggaata ccgccagcaa cagcagcaag aggattcatt cgataataac aatccaatgg
     4441 atattcaggc tgacgacttg ccattctaat aggaggtact gaatgggaat gaaggaatat
     4501 gctttggctt atcaaaaaaa aggattttct gtattgccca ttagtccaac tgggaagaag
     4561 ccgatgattg cttttgcgga taagccgcct atgactgccc aggaaattga agatttctgg
     4621 actcagtacc cagatagcaa tatcgctgtc cggacggata agtttttcgt cattgatatt
     4681 gacttacatg ggaaagctaa tggatttgag agtttggcca attgggaaca cttggatctt
     4741 atcactccaa ctctacaggc caaaacggcc agcggtggca aacatatctt ttatttcaaa
     4801 catccagatg tgtctatgac gcaaatgatt ggcttccttc cgggcgtcga cgtcaaagct
     4861 catcttaata actatgttct ggtggcaccg tctaaaactc ccaaaggtgt ttatgcctgg
     4921 gataaagaca agtcaaaaga ggatggcacc atggtcacag ctagtcgaaa gttagtcatg
     4981 gccatcaaac aagagtacaa caagaaaaat ccaggtagtg acctggataa tatctactat
     5041 caaattagca aaggtgctgg taagcggaac cggactacgg aactgtttga aatgattgtt
     5101 ttgggatttg gagaccaggg cgggcggaat gatactcttg caagatttgt cggtgggtta
     5161 ctgagtcggt cggtggatcc agaatgtatc ctgcggcttg cggaaacggc caataataat
     5221 tctgttgaac ccttgggcaa aagagaaatg agacggacaa tcgaatcgat gatcaaaaaa
     5281 cacatgaggg ggggtggcca caataggtga aattgttaat atttcaatca agcagttttc
     5341 acgacgaaaa aagaaaatcc tgagcgaaga aggtgaacag attgaagtag aatccattgt
     5401 ggcagacagc cctagaaatg tcttactggc gatgaaaagc gataacaagt tgaatgattt
     5461 tctccggcac aatgaattca ccggtgaaca tgagattgtg gaggatgtaa aactggacgc
     5521 cattcagctt cgacgtgggc agcttccatc tacttttgag tcatatctga gcgtctattt
     5581 ggaaaatcat ttcaaaacag tttttaaggc tggagcttta agagatggca ttgaagcttt
     5641 ttttgcagaa aaaacctaca atcctgttca ggaatacatg gagcacgttt atgaatcttg
     5701 ggatcacagg gagcggttag ctcaagtttt ccaaacgtgg ctaggtgctg aagacagtat
     5761 ctttgttcag cgtattgcgg tcatgttctt tgtcggtgca gtttcaaagg tgtttaaccc
     5821 ctgggtcaaa tttgactata cattggactt agtcggtggc caaggagcag gtaagaccac
     5881 cttcctgcag aaagttgcag tcgaatggta cactgattcg gcaaaagatt ttatggataa
     5941 ggataattat gaaatcatgc tgaagtctct gatcgtcaac gatgatgaga tggtggccag
     6001 cagaaagacc acttttgatg agctcaaggc atttgtaacc aaaactgaac tgtcgtttcg
     6061 taggtcttac ggtcgcagag ctgaaaaatt ccctaaaaac tttgtgattg ctaggacatc
     6121 gaacaaggtt gagtacctag gagacaaaac tggtgagcga cgctttctgc cagtgctggt
     6181 ggatgcagac cagcagttgg tcaaaccgtt tgatatgact gatcgggatg tgctccaact
     6241 ttggggtgag gcggtcgcta tttacaaaaa agggtttacg cttacttttg atgatgactt
     6301 cgaagacgaa ctggcggtct ataaggagcg gttcacttat aaagatgaag cggaatcaca
     6361 gatttacgat tatctggaca tgttagttcc tgatgagtgg gaagaaatgt cagtggttca
     6421 gcaacatcaa tatacctggg catactttaa taatggcagt tatcgtaatg agtcgggatt
     6481 tgtctatgaa ggtgttaaac tgcaagcgag tgtttccgcc aagcagattt tgaaaaacgt
     6541 atttgatatc gacagtgcaa gaggtgagag aattgctcgc aaaatcaagt tgattatgga
     6601 caatcatcaa gattgggaat accgaataaa gaagataaaa gggagaactg tcagggcata
     6661 ttttaagaaa aatatgcaaa atgaagtgat gtaacctttt aggctaaaaa aggctaaaaa
     6721 agcttaaaaa tggcgtttgg gttacatcag gttacatcat tgatgtaacc tgccgaaaat
     6781 ccattaataa caagggttta gggctatttt ttgagaaaaa ttcaaaaaaa gtgatgtaac
     6841 ctatctaaag ccttgatatg actggt
//
LOCUS       DARYUW010000080         6771 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYUW010000080 DARYUW010000000
VERSION     DARYUW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6771
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..692)
                     /locus_tag="TVW11_001806"
     CDS             complement(<1..692)
                     /locus_tag="TVW11_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEL1365878.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLAT"
     gene            complement(819..2435)
                     /locus_tag="TVW11_001807"
     CDS             complement(819..2435)
                     /locus_tag="TVW11_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1365879.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(2851..4395)
                     /locus_tag="TVW11_001808"
     CDS             complement(2851..4395)
                     /locus_tag="TVW11_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1365880.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(4564..5259)
                     /locus_tag="TVW11_001809"
     CDS             complement(4564..5259)
                     /locus_tag="TVW11_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1365881.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(5343..6728)
                     /locus_tag="TVW11_001810"
     CDS             complement(5343..6728)
                     /locus_tag="TVW11_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1365882.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2014 a         1622 c         1259 g         1876 t
ORIGIN      
        1 gtcgctaaaa aaatagagcc taaaatgaaa ataccccgat gattttccgg actaaccaat
       61 aagtgcagcg cataataggg attgatagcc tttaggattt ccaaatgctg taagctattc
      121 aagagaccac tgatccccaa aacgctaaac caaaccagca tgactggccc aaataattta
      181 ccaataacac ccgttccaaa gcgctgcagg ccaaacaaga ccatcaatat cagcaaggtc
      241 gttaggatca cattggtctg attctggtaa atactgctga gctcaggaac agcctttaag
      301 ccttcaatgg ctgatgtgac cgtaacagct ggtgtcaagg caccatctga taagagcgtt
      361 gctcccccaa gcatagctgg aatgattaac caccttgaca tccttctaac taaggtaaag
      421 agtgaaaaaa tccctccctc atgatgatta tcagccttta aagcaatcaa aacatacttg
      481 attgtcgtta ccaaggttag agtccaaata atcaaggata ctgagcctaa aataaaagct
      541 tcagacacct gtgaaaggcc gccttgattg tcaaccaacg actgcatggt atacagtgga
      601 cttgtgccaa tatcaccata gacaattcct agtgcaataa taaaacctgc ctttgttgct
      661 ttatcaaagg catcatgatg ggcattagac atcccaatgt tcctcctaag acttaatcat
      721 gccaaatgga ctgagaccat tatagcaaaa tctataacaa aatcaatatt ttcagaaaat
      781 taaaaagaga gctgacaatc atcagctctc ttgaaacttt agttcccttt atgacggata
      841 ataaatccag acgtcttagc ttcgacagcc ttgcccttct tgtgcaggtc cttgttagag
      901 cgtttttgct ttcgcttaaa gtcatagcta ccactgctat catgactgtc acgtttatca
      961 cgccttggac ggcggtcacc atcataaaca tttcttttct catgacgata gccacctcga
     1021 cggttatcac gaccgctacg actacgattg ccacgacctg tcttgccatt tttattgcca
     1081 tgaccaccac caacatactt aaacggtaat ggcttttcac gcgctatctc aacctctggt
     1141 aaggtatctg gatcttggac ggtcaagcta aggatataga gcgctagctc ctctggggta
     1201 aactctgctg ccaatttcat cgcatcgccc ttaaatttct caaagtttga gcgaatagca
     1261 tcatctgcaa aatcacgctc aatttttttg agggcaacct ttttcttagc ctgaaaggct
     1321 tcctctgccg tagctggctt gagtggcttc atgcgcttct tagtcaggtg ctcaatcatg
     1381 gtcagatagc ccatctcatt tggtgagaca aaggtaatgg attcccctga cttacctgca
     1441 cgaccggtcc ggccaatacg gtgcacatag ctttctggat cctgtgtaat atcgtaattg
     1501 tacacatgag taacgcctga aatatcaagc ccacgcgcag caacatcggt tgccactaaa
     1561 atatcaagtt gatcattttt aaagtcgcgt atgacacgaa ggcgcttatt ttggtcaagg
     1621 tcaccatgta tcccttctgc gcgaaaacca cgcaatttta agccgcgcgt gatttcatca
     1681 acacgacgct ttgtgcgacc aaatacaatt gatagctctg gctgctgaac gtccatcaga
     1741 cgtgtcatgg tatcaaattt ttcttgctcc ttaacacgca catagtattg atcaacattc
     1801 acatttgtta attccttgtt tttaacctga acatgctcag gatccttcat aaacttgaca
     1861 ccaatttcct tgattggagc tggcattgtt gctgaaaata acagggtttg acgatcgtca
     1921 gggacacgac taataatcgc ttcaatgtcc tctaaaaatc ccatattcaa gcattcatca
     1981 gcttcatcta aaatgagtgt ctcaacatgg tctagcctca aggccttacg cttaatcaaa
     2041 tctaacagac gtcctggcgt tccaacaacg acatgcgccc cagactttag ggccttaatt
     2101 tgcttctcaa tgcttgagcc accatatact gagcgaacct tgacgccttt atcacgacca
     2161 aaacggaaca gctcttcctg actttggaca gccagctcac gcgtcggagc aatcaccaat
     2221 gcctgaatgg tgttatcggc tgtacgaatc ttattcagag ttggtagacc aaaggctgct
     2281 gtttttcctg ttcctgtctg agcctgtccg ataacatctc gtccctccaa ggctaacgga
     2341 atggtcagct cctgaatagg agaggctttt tcaaagcctg ctgtaacaac agctgactga
     2401 atatcttctg ataagttaaa tgctgtaaat ttcaattgtt tctcttttct aaaaaggcag
     2461 tgcgaagctg ccttataaac cttttaatat tgtcgttcga ttaacaacct atttagtgta
     2521 acataattaa tattaaaaag ataggaaata agccatgaaa gtgtttttat ctcaaaatga
     2581 ttaacactat caggcagcta aattgataaa agcgtcactc cttattgctg attggctaac
     2641 agcctcaaaa aggcctcgtc ggacttgctt acctatgctt tttatctact ctgctaaaaa
     2701 gactcggcac agagacgagc cttcgcgatt ccatcaccaa tcttcaaaga cagcaattag
     2761 gattcctgaa agctccttat gccaatagcc tgccttttct tagcagcaga agtgcaaaaa
     2821 cggactaggt tcccctaatc cgcttagctg ctacattttt gcttctagct taacatctgg
     2881 gtatttatct gcaaaccaac gaagcgcaaa gtcattttca aagagaaaaa caggctgatc
     2941 aaagcgatcc cttgccaaaa tgtttcggct tgaggacatg cgttggtcca aatcctcctc
     3001 tgagatccaa cgaacagtct ttttgcccat tggtgtcatg atgacctctg cattgtactc
     3061 accctccata cggtgcttga aaacctcaaa ctgcagctga ccaactgcgc ccagcatgta
     3121 ttcacctgtc tgataattct tataaagctg aacagccccc tcctgtacaa gctgctcaat
     3181 acctttgtgg aaagattttt gcttcatgac attcttaggt gcaaccttca taaaaatctc
     3241 tggggtaaag gtcggcaatg gctcaaattc aaacaggttt ttactaacgc tcaaggtatc
     3301 tccaacctga taagtccctg tatcgtagac cccaataata tcaccggcaa ctgcattttg
     3361 gacattttca cgagactcag ccataaactg agtaacattt gatagcttaa cgcttttacc
     3421 tgtacgagac agctttacag ccattccctt ttgaaactct ccagagacaa tacgcacaaa
     3481 ggcaatgcgg tcacgatgct tagggtccat gttagcctga atcttaaaga caaagcctga
     3541 aaaatcctga ttgaggggat caatcatctg gtccgttgtc gtcttatgcc catgaggctc
     3601 tggtgcaaag gctaaaaagg tatctaaaaa ggtttgtacc ccaaaatttg ttaaggcaga
     3661 gccaaagaat accggagtca gctgaccatc taaaatagcc tgctctgaaa agtcattacc
     3721 tgcctcctcc aagagctcaa tatcttcaag cacctgctca taaaaagggt tgctggcaaa
     3781 aatccttgcc ccctcctcta aatcagcaaa cctctgctcc cccttataaa gctccaagcg
     3841 tttgttgtgc aaatcataca gaccttcaaa ggctcgtccc ataccaattg gccagttcat
     3901 ggggtaagaa gcaatcccaa gaacctcttc tagctcctcc aacaactcca aaggctcacg
     3961 tccatcacga tctaatttat taataaacgt aaaaacaggt atgttacgat gcttaacaac
     4021 ctcaaagagc tttttcgtct gtgcttcgat ccctttagcc gaatcaacaa ccatcacagc
     4081 agcatcaact gccattaagg tacgataagt atcctctgaa aagtcctcgt gaccaggtgt
     4141 atctaaaata ttgatacgct taccagcata atcaaactgc atgactgatg atgtgactga
     4201 aatcccacgt tgcttttcaa tatccatcca atctgactta gcaaattgac cagatttttt
     4261 tcctttaacg gtcccagcct cacgaatctc accaccaaaa taaagtaact gttctgtaat
     4321 agttgtttta ccagcatctg ggtgactgat aatcgcaaag gttcgacgct ttttaatttc
     4381 ttctgtaatt gacattcttt tttccttatt tgttcacatt gcagagcaag actctgatta
     4441 atagcttcaa gtcacacgtc acagttatgt ctacatgatc tcactcctaa atactgatat
     4501 gataaaaaga gctgctagag cagctccttt attatagctg attcgaagcg ctttttcaac
     4561 gccctatctt tctttagaga gcttcagctc taactgattg gcctcactaa atctcacata
     4621 gataagttca atcagcttaa ttaaaccagt caaccccatt gtcacaatga caaaattcat
     4681 aagcaggtga tgcgtatgaa taatcggaat atccatcaca aagccgtaat ttccctttgt
     4741 tgccaaattg atcaatacta aaacaaaatt aatggttgcc aagtaacggc aaacaaggac
     4801 tggctttagc tgacttggat tgtaaaaccg cagcaggtaa accaagccat tgaccaaaag
     4861 agcataatgc cccaggtaaa aagaaatatt agccacatgc catagctgat aagggtataa
     4921 atcaggtgat aacagggcca aaaaggtccc accaatccct aaaaccataa aaagctgctt
     4981 taagctactg cgatccggta agaaaaagat agctagcatg gccattcggc aatggtaaag
     5041 cggcaaagcc tctgtcaacg gaaagcctcg caaggcatac cagctataca aaccaaccaa
     5101 ttggaccaac tgaagcccta agaagatata gcgatacgac tttagctgat agagctgcag
     5161 ggtcataaaa accaaaaacg gcgctatcat caccgacaat agataaaata gcaaggacac
     5221 atgcggtagc ccaataggtt caattgcaaa aaaattcata aacatccctt tctacatttt
     5281 ttcattatac cttaatctta atgagaggac aagatgtttc atgtgttttt tctgaaaaag
     5341 tgttaggagg acttcccagc atgaggagct gtcaggcgat caaccacatt tgctagcagc
     5401 atggagtggc tgccctttag cagcatctgg tcattaggct caagaatagt caacaggtac
     5461 tggcacatgt cctcgtattg atcctctcga ttattctttt taaagaagct aactctgcca
     5521 cttggataat cttgactagc tagcttggcc aaggcttgaa tatcatcacc gtaaaagacc
     5581 aattgatcaa tacgcttggg atctaagctg gtaatcagct gagaatgcaa agcaactgag
     5641 tcagcaccta attccttcat atcagctaaa acagctattt ttttgccatt agggttggcc
     5701 ggaatggcag caaaggtttc caaaattaac cgcatagcag ttggattggc attgtacaca
     5761 tctgccaaaa ggtcggcgcc attagccgcc ttgacccact cggttcggtg gcgtgtcagc
     5821 ttgacggttt ctaaagcttc tataatatcc tcatcaggca cagccaagag tttaccaaca
     5881 taagctgcta tcatagcatt ggttgcattg tattttccag ttaagggaag agtgaccggt
     5941 cttggtaaga cattagtcct aaaggtcaag gagtccttgc actctttgat atcctcaacc
     6001 accagctctt gatgatcgcc aaagcgaatg accatctgac tatccggcaa atatggatca
     6061 aggataggat caccaggagc aattaaaatc ccgttagagt ccatcccatc aacgatttgc
     6121 attttccctt cggcaatctt ctcgcgagag ccaaagtagg ctaagtgagc ctcaccaata
     6181 agggttagca atgcaatatg aggtctggca attctagaga gcagctgaat gtctcccata
     6241 tgatcctgcc ccatctctaa aacaatcttc tcagtatcct ctggcatgtg aagcaccgta
     6301 taaggcaagc caatgtcatt attataattg ccctgggttt tgtaggtctt ataagctttt
     6361 gccaggaccg cttcaatcat atccttggtt gatgttttac cgtttgagcc tgttacagca
     6421 atgacatcga cacgtagctt atcaatataa tactgggcta atttttgaaa ggcagccaag
     6481 caattctcaa ctagtatata gggtctgcca ctgattgctc tttctgaaaa ggtagctacg
     6541 gccccatttt caaaggctaa gtcaataaaa tcatggccat ctcgctcacc ctgtagcggt
     6601 aaaaaaagat caccttttgt gatgtttcta ctgtcaaatt caatctgatt cagaggaacg
     6661 tcgtctaaat cagaaagact attttgagca tcaacaactc ttgccacttc atgtaatgtt
     6721 aatttcatct tatttttcct cttaaaacac tggtttttaa agctttgctt a
//
LOCUS       DARYUW010000081         6637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYUW010000081 DARYUW010000000
VERSION     DARYUW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6637
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            232..1071
                     /locus_tag="TVW11_001811"
     CDS             232..1071
                     /locus_tag="TVW11_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1365883.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(1167..1727)
                     /locus_tag="TVW11_001812"
     CDS             complement(1167..1727)
                     /locus_tag="TVW11_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1365884.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(1740..2213)
                     /locus_tag="TVW11_001813"
     CDS             complement(1740..2213)
                     /locus_tag="TVW11_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1365885.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(2219..2968)
                     /locus_tag="TVW11_001814"
     CDS             complement(2219..2968)
                     /locus_tag="TVW11_001814"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1365886.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(2958..3707)
                     /gene="truA"
                     /locus_tag="TVW11_001815"
     CDS             complement(2958..3707)
                     /gene="truA"
                     /locus_tag="TVW11_001815"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1365887.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            3894..5258
                     /locus_tag="TVW11_001816"
     CDS             3894..5258
                     /locus_tag="TVW11_001816"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1365888.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
     gene            complement(5736..6221)
                     /locus_tag="TVW11_001817"
     CDS             complement(5736..6221)
                     /locus_tag="TVW11_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1365889.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(6310..6383)
                     /locus_tag="TVW11_001818"
     tRNA            complement(6310..6383)
                     /locus_tag="TVW11_001818"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6347..6349),aa:Arg,seq:acg)
BASE COUNT         2019 a         1652 c         1162 g         1804 t
ORIGIN      
        1 tttgcctttt atttatctca taatcagact cattcgctct aatcttttgc acatgttaat
       61 gtcatttatt tgcagaccta cgcaaccaat tgcacagagc tttgtttcct tcgtcagaaa
      121 aacctcaata aaacataaac aagaagccat tactcttctt gataatgttt ggtgatctat
      181 tttcaaccag gacttttttt ggtaaactag ctacgataga aaggagttgc catgacgttt
      241 atattaacat actttaatca gctacaccta gaaaatatca tggtgcttgt gttttctaaa
      301 ttagtgtcaa tcaccttatt attgattttc tttgtgatct tcaaaaaaat cacgacagct
      361 ttatttgaaa aggcaatcgc caagtcattt tcctattcaa gacaaactga agcaaggaaa
      421 aaaaccttat ccaagctcct tcacaacacc ctaaattatg ttttctattt tcttctcatc
      481 tattggattt tgagcctact tggtattcca gtatctagtc ttttagcagg agcaggaatt
      541 gctggtgttg ctattgggct tggggctcaa ggcttcttgt ctgatgtggt caatggcttt
      601 tttattctgt ttgaaaatca atttgaagta ggagacaccg tcaccattgc aggcattgaa
      661 ggaaccatct ccagcgttgg tattcgaacc actcaggtgc gaggctttga tggcacacta
      721 cattttattc ccaaccgcaa tattacagtt gttagcaaca aatcacgcgg caatatgaga
      781 gctttgatcg atattccact ttattcctca accgatctag agcatgtgac ccaaatcatc
      841 aaggctgtca ataagcgaga ggtgccaaat ttcccacaaa ttgtcggaca gcccaacatt
      901 ctaggaccac aaaccaatcc caacggacaa ttcacctttc gcgttagcat ttttactgaa
      961 aatgggcagc aatttacgat ttactatagc ttttataagc tctatcaaga ggccttacta
     1021 agggagggta tcaagctacc aactgcatct gccatatcac ccttagccta gcagtaaaaa
     1081 ccattgcttt cttagcatac aaaagcccta tcccgcagcc aggtcatcag acttagactg
     1141 ctagataggg ctatttcttt tggctcttat ttccgaatag gatcaggctg atacctggct
     1201 cttacaccac caattaattt gggccgactt gctaaggcag tcacatgagc accaccaagc
     1261 tctcgctgaa taggcacaag cggcacctgt acacgcttaa catgcatacc aattgaggta
     1321 tctccaatgt caaggcctgc atgagcagca atggcttcaa cctcaactgg ctgcttcatg
     1381 tatttgaagg ctgctaattg accacttcct ccagcatgca agctaggcag cacattgact
     1441 atttctagcc gatattcttc agcaacactt tcttctaata ccaaggcacg attaatgtgc
     1501 tcacacccct gaaccgctaa atgaatccct ctgaacgaca attcctccaa tataagcttc
     1561 acaataacct cgcccacctc taagctagaa tgctggccaa tacgaccacc aagtacctcg
     1621 ctagaggaca gccctaagac aaacagttgc ccttttttga tagcactacg ctccacaata
     1681 tcaagcaaga tagagcgtgc ttcttctctc aatactttta aattcattga atcacctgct
     1741 taatcatctg acactttgac cagctgtttt ttgaccccta aatacagcag atagcctaca
     1801 cctatgccaa gggtattttg agcagcattc cccgaaattt ctgaaatagc agcgcccata
     1861 ccatacattg gaatagctgc aagaaaatac agaccaacca ttatcacaga agcaaggccc
     1921 acgccaagaa agcgatgcct gccaggcaag cctgctaagt agccctgagc cccatgagca
     1981 acaagactaa tcagcatcca attggggtaa cctgagatca aatcaagcaa aaaagctgat
     2041 aagcccccaa caagcatacc ctcctttttc ccaagagaaa aggcagtcac atacacccct
     2101 gcatctaaaa gacttaaaaa acctgtcggc gtggcaatac tcacaaacct gcccaggaca
     2161 actgtcaggg cagtcaagat agacacaaga gctagctctc ttgtctgttt catatttatc
     2221 ataagacaac tccataatca tttgactgtt gaatggcttc aaaaacaagg tctttagcct
     2281 gctcaacagc cctaagcggt gaatatccct tagctaaata agcagcaatt gcagctgcaa
     2341 agctacagcc agccccactg ttttgtttgg ccaagactgg cttttctaaa aagcacaggg
     2401 tttttgcgtc ataaaataga tctagggcaa ctcgttgatc aaaacgattc ccacccttga
     2461 tcacaaccct cttagccccc atctcataaa gcttttttgc cgcttctacc atttgctccc
     2521 tgctattaat agcaagccct gccaagcgtt ctgcttctct taggttggga gtaatcactg
     2581 ctgttaaggg aaaaagagag cgcaaagcct gtgtcatttc cacaactgtc tgatcttgat
     2641 tttccttaaa tactaaaaca ggatctaaaa caacagggat atcctttttt agctctaaaa
     2701 acagggccac ctgctctgct atttcaggtc ttggcaaaag accaactttg attgcctgaa
     2761 aaggaatagc tgctaagcta gacaactgct ttgccagcaa atcagtcgca acagggtgaa
     2821 tgctgaaacc tttagcatca cagcttgtta agcaggtgat agctaaaaat gcaaagctat
     2881 cgagctgatg aagcactgcc aaatcagcct gcaaaccacc accgctgaat atatcactcc
     2941 cagcaatcgt taatacctta ttcttcataa atgatttcct tcaaataaag accattacca
     3001 gccgctgtcg gtccagctag ctgccgattc ttactctcta aaacgagcct gatttgttca
     3061 atgggcaacc gaccattgcc gatcttaagc aaggtcccaa ccatatttct aacctgctta
     3121 taaagaaagc cattccctga aaacgtaaaa acaagaaaac cagttttagg gtcctgagtg
     3181 agggtagctg ctgtaatggt acgaacctta tttttaacag aggttcccgc agctgtaaag
     3241 cctgtaaaat catgcgtccc aaccaaatcc ttaatcgcag cctgcatttt cgcaatatct
     3301 aagggataag ggtaatgggt cgcataatgg cgcatcatag gatttttagg acgaccaata
     3361 tccactaaga attcataggt tttgaaatgc ttatggtagc gagcgtgaaa atcatctgct
     3421 gcaatctcca gactgatcac atcaatatca tctggtgtct gggtatcaag tgcaaagcga
     3481 agcttttcag ggtctctttt ttgctccaaa tcaaagtgaa tcacttgacc ataagcatgc
     3541 acacctgcat ctgttctacc agctccatga atctgtatcc cttgaccacc tgtcaatttt
     3601 tgcagggtct tttcaatctc ttcttgtacc gtacgtgcct gactttgtct ctgaaaacca
     3661 gaaaataagg tcccatcgta ggaaataatt gctttatatc ttgtcatgct attattctac
     3721 catttcttcc agccatcaga aaagagcatt tacggctttt gtccccatac agttttcgat
     3781 tagctttgat aatcaagctt gatttgacgc caacaggcaa aaaaaggcta ctgacaagga
     3841 ctagcttttc tgctataatt tctctaatat tcaataagta gactggagag caaatgaagg
     3901 taacaaaatt tggcggcagc tccttagcat ctgcccagca gttagaaaag gtcttggcta
     3961 ttatcaagga cgatcctgag cgtaaaatca tcgttgtctc cgcaccaggc aaacgatccc
     4021 ctacagacac aaaggtgact gatgcactca ttgcttatta caaagcctac gtctcagacc
     4081 gtcattatca caagcatttg gaatggatta tcaatcgtta ccaacaaatc tgtaatgacc
     4141 taactctaga tagcaaaatc atcacccaaa ttaaagcttc cttagagcaa ttggcacggc
     4201 ttccaaaaga acataatccc tatttatacg atacctttct tgcggccggt gaggacaata
     4261 atgctaagct agtagctgcc tacctcaagg caaatggctt aactgcaagc tatctccacc
     4321 ccaaagatgc aggtctaatc gtaagcagtg agccacagca tgcacgtctt cttccaatca
     4381 gttacgataa gctagaggcc ttaaaggatc atgatgacat tcttgttatt cctggattct
     4441 ttggtgtgac aaatgaaaac cagatttgta ccttctcacg tggtggctct gatattaccg
     4501 gctccattat tgcagcagga gtcacagctg acagctatga aaattttaca gatgtcaatg
     4561 gcatctttgc tgcccaccct ggtgttgtta agcagccaca gacgatcact gaattaacct
     4621 acagagaaat gcgcgagtta gcctatgctg gcttttctgt cctccatgat gaagcattaa
     4681 tccctgctta ccgagggaaa atcccaatcg tcatcaaaaa cactaacaat cccagccacc
     4741 caggtacaac aattgttctt gagcaccaga ggaaatccaa tcccgttgtc ggtatatcag
     4801 gtgatgatca ctttgtcagc attaacctat ctaaatacct catgaacaga gaaattggat
     4861 ttgggcgcaa gctccttcag atattagagg acctcaatat cagatgggag cacatgccta
     4921 caggtattga tgacctatca attgtactta gagaaagaga attgaccccc atcaaagaag
     4981 aagaaatcct tcgcagactt gtccagcaat tagaggttga tgaggtgtcc atcaccagga
     5041 acctttctat tatcatgata gtcggtgaaa acatgaaaag tcatattggt gtcacatctg
     5101 ccgcaacaaa ggctctatct gaacatcata tcaatattgc tatgatttcc caaggctcaa
     5161 gtgaggtatc tgtcatgttt gtcatcaata gcaccgatga aaaaaaggcc attagagcct
     5221 tatatcaaac cttttttagc cctgatcgac ccctgtaaag ctccatataa catctcttgt
     5281 taacaccaag cttcaaaaac agctcacaag ctagacagta ctcctagcct atgagctgtt
     5341 ttgatgatct aaaactatca agattaagca tcggtagtaa cgacttaata tgctcacagc
     5401 tatcataaac tctagcttta ccttattgag gaaaagaaaa ccagttttca cctcagctaa
     5461 gattaacaac aagcgattaa gcacttgcta aaaacagata gacttcaaaa gtgagacata
     5521 tgtataattt ctaccagatc taaataaata tagcagcaga gcaccgagtt taataagcca
     5581 tttctgacat gataaactcg ccaagctctc cacagatcaa gatttgcctt atcaattgat
     5641 acaacagcca gcattctcaa agatgcacaa gatccatcac agtctagcca tctccctgca
     5701 cagtaagcct ttcaatctcg ttccggtaac cccttttatt tctcaccagt aaagtcctga
     5761 aagtaaggtc ctatcttgcg aagcaaggcc cgtctcccct caaaccgctc tcccctgatc
     5821 aaagcccgaa actgcgacag ctcaccctct gtcaatcgct cctcaacctc cttcacaatc
     5881 aactgataag ccacataatc atctactccc aaaccacctg ctggtatcgc atggcctacc
     5941 gacccaatct cctcataagc catcttatga aaccgacgct tctgactctc ctgctgccgc
     6001 aacacgtcct tcaaataaga ggaaaacttg gtcttaaaat aacgatatag cttctcctca
     6061 tcctctatca attctggata agtgaccaat aaccgataca agatcaaccg cccctcctgt
     6121 aaccaatcat ctagctccca cagctgaata taataatgct gtcttagctt cataataata
     6181 ggcttgatct tatcaaacaa cctcactaaa tcatcagtca ttatactttc tccttttcat
     6241 gcttagtagc cttattataa ggagacaaac aaaaaaacaa caggacagaa atgtcctgtt
     6301 gccttgctat gcaccctaga ggagtcgaac ctctaaccgc ctgattcgta gtcaggtact
     6361 ctatccagtt gagctaaggg tgcttttctt aactattact atcctaccat actatcccct
     6421 aaaaagcaag gctctatacc atctggaata ggtaagtcca ctgtggaaat catagagctt
     6481 tttgagtaca caaaaaagag agcaccaaac tgatcctctc taaatgtccg ttgttagtca
     6541 acccactata gttgacatag agccaaactc cgccagtagg actcgaacct acgacatcat
     6601 gattaacagt catgcgctac taccaactga gctatgg
//
LOCUS       DARYUW010000082         6568 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYUW010000082 DARYUW010000000
VERSION     DARYUW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6568
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(369..749)
                     /locus_tag="TVW11_001819"
     CDS             complement(369..749)
                     /locus_tag="TVW11_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1365890.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(783..1775)
                     /locus_tag="TVW11_001820"
     CDS             complement(783..1775)
                     /locus_tag="TVW11_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1365891.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1791..2336)
                     /gene="srlA"
                     /locus_tag="TVW11_001821"
     CDS             complement(1791..2336)
                     /gene="srlA"
                     /locus_tag="TVW11_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1365892.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2472..2933)
                     /locus_tag="TVW11_001822"
     CDS             complement(2472..2933)
                     /locus_tag="TVW11_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1365893.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2933..4705)
                     /locus_tag="TVW11_001823"
     CDS             complement(2933..4705)
                     /locus_tag="TVW11_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1365894.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4999..6348)
                     /locus_tag="TVW11_001824"
     CDS             complement(4999..6348)
                     /locus_tag="TVW11_001824"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1365895.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         1917 a         1564 c         1307 g         1780 t
ORIGIN      
        1 gctttattgc ttattatacc ttgtcatatc attattaatt agctatggta tgtcccattt
       61 tcttaacatg gaatttaaat ggtggaataa attagctata tctctaacat ctttatatat
      121 tatttatcaa atgctgaaaa aggataaatt aattaaataa tcaactaatg tacaagttgt
      181 ctttaagctg aaaagaggct atcaacagcc tctttttttg atgatataga taagcccaat
      241 gcttccttag aagagctctt ctgtgagatg accttatcac ctgacattag ctgcttggct
      301 catgcctaca gctaaaggaa atgccctgca aggatagcag cacttagcct gctggtctac
      361 ggcgtgtctc agctgcacct aagccaagca aagatttgta ctaggctgcc ctgcctgacc
      421 tgtggcagcc ctttgccctt gacatgcaga gtaccgggaa gagagctggc tgtggagcca
      481 tcaaaagaaa tggttatatg ccctagctga gcaagatttt tttcaacaac agcacctact
      541 gctgtgatgt catatgccat ttgatcaatg actagctgac caccagcaga gatagaccca
      601 gacacttgct tgttgtcaat cgtatagcaa aagtctgcca agtctgccgg tgctccctga
      661 tcaaaaagaa taagcatatt ggcagcacta atcatgtctg ccgcctccga tccaatagcg
      721 gtaactcttg tttcaaatac ttttatcata cattctctct cttcctatca tacgatagct
      781 ccttactgat acaaaccaat acttgcaatc caagcaacaa caacccgagg aacaccattt
      841 aaaaagcgtg aataaagcac agatggcacc ccaacctcta ctgtctcagc attagcctct
      901 gataaaccaa gcgctactgg aatgaaatca cagccatttt gcgtattaat agcaaaaagt
      961 gcaggaagag ccatttgtgg tggaatagtg ccttttccaa tctcaacacc aatgagcgtt
     1021 ccgatgattt gactaataac cgcaccaggt cctaacagcg gtgataaaaa tggcaacgaa
     1081 cagataaagc caatgataat caagccccaa atattaccag ccagcggtac catgagcttg
     1141 gctagccaat taccaacacc agagccttgg ataaaaccaa ttaaaagaga gacaaatgcc
     1201 atgaatggca aaatcgtatt gattaaggtc tggatagcct cacgcgccgc ttggttgaag
     1261 atagcaacta ccttacctgc tcccatacca atgcgggcaa caaagctgct ttctgcgcgc
     1321 tgctcagtaa tctttttgct agtatcatag ctgctagcct ttggaactga tgactcctta
     1381 gcactagcaa catgagcctg agcgtcactg gctgtgattt gctcaagacc tacagcagac
     1441 acgtaaatgt cctcggtaat gtactgtgcc aagggaccgc ttttacctgt cgccacgata
     1501 ttaatggttg gaatgccttt tttagggtaa ataccgcagc gtagggtgcc gccacaatcc
     1561 acaatagcta gggctatctc atcatcaggg attgaggtca caaagccatt gaccgcctcc
     1621 atacctgtta gggcagcaat tttatcgaca atgtcaggct tttttccacc gccagtaata
     1681 tagataaatt tgtgcttagc ttctgttggt gtaatggtta gcggcccacc atagccaccg
     1741 ctccccttaa caactgtaat actgtgataa gtcatcatgc tacctctctt ctataattca
     1801 atcatcttac ttaatgtcac accctgctgc ttggccacgt aggctgtcgt aaagtcagtt
     1861 acccagccac caacaaagtt catgattaac ccaaccaaga ggtaacgaat cgccaagtcc
     1921 atttggctca agcctagcgt cttgatacct gaggcaatac ctaaccagac aaacaattct
     1981 cccggattaa tgtgtggaaa gacaccgttt gacgtatgac aaaattgcat ttgagcggca
     2041 acatagcttg gcttgtaata ctcgggcata aagcgtccca tgctgattgc catcggatta
     2101 cccagcataa aagctgaaat aaaaggcaat accatgtagc gactgatagg gtttttagca
     2161 gagatttttg ccaattgatt gaccctttga tctcctaaaa taccaattaa ggcattcatt
     2221 gcaaccagca gcatcaagac caccggcaca atgccagtca tccagctgac aaaggtttca
     2281 ccaccaagct ggaagagctt cataaagcct tccgcaaatc ttgttatcat ttccataaat
     2341 aaactcctca tatgatgtac ttacaagcaa gacaatacaa atgtactgcc tgcttgataa
     2401 tagctgcttg agctggactc aaaacagctt ttatgttgac aaggcaagca atcaatcctg
     2461 cttttggcac cttacttgaa gcgtgccagc agctgcttgg cctgtagggt ccaatcaaag
     2521 gctgaggcat attttggtgc gtcctcatag acccctgcct caaccctcaa gaagacctct
     2581 cttgcgtcct caatagccaa gcgcagcaat ttattttctc gtctaatcaa gggattgtag
     2641 cgatcaaaat aatgaatatc ctgaccgata taagctggca ttggcttaaa cctggctgcc
     2701 actgtcacac cctgcatttg cctagcatct aataccttac ctgactgatc caaggcaaac
     2761 atgacaatgg ttccggccct gattttcccg gctctacggc caatagcaac gcgcccctgt
     2821 cgtctaagac tggcataaac agcattgaag tgcttaagct gtctcagacc tagcaataat
     2881 tgaaaaaggt aagcaactat gacaaatagt ccaaaaataa ccataaaact cattaaaaaa
     2941 ctcctttttc cttggtaaat gcaataaact cagcttgact ttttaggctc cttagctccg
     3001 cctgaagctt atcatcgctt gctattttga aaatatcatc ataaattttc aagagatcag
     3061 cctccatctg cgcttcaacc ctcttggaaa tagccactag aaaaataaac tccaccagac
     3121 agtcatgctc acgataaggc tcgtctaata gacccagcag caggacagtc tttgtttcct
     3181 tgtcattaat cgtatgtgga aaggcaatgc gattgccaaa taaggttgat tgcagggcct
     3241 cacgctctag caggcgttga ccaaactgcc tgtcaaccag ctgcttttcc tcaagcagct
     3301 ccgccatttc agtcaggtag tcagtgtagg ccttcccctt tgacagacga gcaaagtgta
     3361 gggtgatggt cgccaggttt ttctggtgat aatgatgtac cctgcgccat tcattttgca
     3421 gccactggtc atcaaacaga tttgtgattt ggagaacagg agattttagc tgaccaaact
     3481 tcagcggcac agtggtgaat atggcaaaat agtgatcatt gtcatcagga ttgaattgct
     3541 cctcagagaa ttgtgagatc aacaaatcag gacctagcac cttgctcaag cgacgacaaa
     3601 tcatattggc agtgccacga cctgtcgtgc agacaacggc aatttttttc actgttggct
     3661 ctgtcacatg ctcagcgtct ttcatcatca tttcgaaata aagggccaaa tagctacact
     3721 cagacaattc tatggcgcag tcaaactcct ctgctaagac ctgagctgcg acaatggcca
     3781 tatcaaaggc caaggggtat ttgtatctaa tttctccatg aaaaatatca ttggcctgaa
     3841 catgaaaaat caaacgattc accaagagct tcaaatgcgt atgcaaagca acaaaaagct
     3901 tgtcttggtc aatagtcacc aagagactgg tcttgatgtg ctcaatcatt tttgaataaa
     3961 gcctgacaat gctctgttgc agaggctttt cttgataggc tagatcctcg atgtattgga
     4021 tattcaaggg aaagctaata aactggcgct cgtattgact cagtgacagc tgataggcta
     4081 gctcaatgtg atagaccagc tcctccataa aggcactgga atcaacctca ttgctatagt
     4141 aaggaatagg atctgtcaga tacctgccct gacgcattcg ctcaatggtt atcgcaaagc
     4201 tcttggtcaa aagctcttgg attttgcgag gaagctggta ggtctgatac agctcatcta
     4261 gaaaaaacaa gctatcacca cacaagccct gcggctcaaa gtatttgtaa acctcatgaa
     4321 cataaagcag ccgaaggttc aactcagtgc caacagcctg tatgccatga ttgggcttgc
     4381 cctgaatcat gaccgaatag gtcctagcaa gagccttggc tgcctttagg tctttattga
     4441 tcgtgctgcg actgacgcca atctcatcag ccaaatcatc aatgactaaa gctgaggagc
     4501 tttgcagtag cctttttaga agataagcta cccgcttgct agcggaatta aagtcactag
     4561 ccttacgtaa actaccagct aatatcgtct ctaatctagc ataatcatag acctgcagct
     4621 gcaaaaaggc gccttgttgg gtgatggtcg catctccatc taaaatgtca ttgagctgac
     4681 caatgctact tgcagcgttt gacatcgtct tttcacaaag tcacagctta gaaagctagc
     4741 agaggagaca aaagcaagac cttatcagct aacagcagca tattaaacga acagctagtg
     4801 atactgatcc tactaagcat agagctccaa aagcctggct taaatagtat tcaaaataga
     4861 acaagagctc tcaagaacaa taacctagcg cactacttgc cttgataagc ctaaccgacc
     4921 ttgaaaagaa gcaaaaaaaa gagcctctca cgagactctt tgttatgttt tagcagacta
     4981 gtctagctag ctctgtcatt acaagcgtgc gttgagcgct gctcctagct cttcaaagcc
     5041 tggcttacca agaagggcaa acatgttttt cttgtaagcc tcaacacctg gctgatcaaa
     5101 tggatttacc ccattgaggt agcctgaaag ggcaatagca agctcaaaga agtagatcgt
     5161 atagcctagt gtaaattcgt cttgctctgg aagcgtgata aacatatttg gcacaccacc
     5221 gtctgtatgg gcaagaagga caccatctgt tgcttttttg ttgacaaagt caacgtcttt
     5281 gccttgtagg tagccaaggc catcaagatc ctcagccatt tctgggataa tcacattttg
     5341 acgtggctta tccacacgaa tcactgtctc aaagaggtta cggtagcctt cttggataaa
     5401 ttgaccaaga gaatgcaggt ctgtcgagaa attagctgaa gttgggtaaa tacccttttg
     5461 gtcctttcct tcagactcac cagccagttg cttccaccat tcgctaaaat actgcaatga
     5521 tggctcatag tttgccaaaa tttcagttac atagcctttg cgatagagga tattgcgaac
     5581 tacagcatat tggtaagcga tgttttctga gattttatct gatgacaggt ccttacgagc
     5641 tgcatttgcc ccctccatca gcgcggtaat atcagcaccc gatgctgcaa ttggcaacaa
     5701 gcccacagct gtcagcactg aaaaacgacc accaacatta tctggcacaa caaaggtttc
     5761 ccaatgattt gcatcagcct caaccttaac agcacccttg accttatcag tcgttgcata
     5821 gatacgcttg ttggcctctt cttgaccgta ctttttaaca agtaattctt taaagacacg
     5881 aaaggcgatt gcaggctctg ttgttgtacc agacttagaa atcacgttaa cagagaaatc
     5941 tttatcttga acatagtcca caagatcagc aagatagctt gatgagatgg agttcccagc
     6001 ataaagaatt tgtggtgctt tgcgctcttt tgctgtttgt aggttggcaa aatggctgtt
     6061 caaaaagtca atcgcagcct tagcaccaag gtaagagcca ccaataccaa tcacaacaag
     6121 aacgtcactg tcagccttaa tcttctcagc tgctttaagg atacgagcaa attcttcttt
     6181 gtcatagttt tcaggtaact caagccagcc caagaaatct gatccaggtc cagtgccctg
     6241 acgtagtgcc tgatcagcct ctgttacctg accttgtaaa aagtcaattt catgctgtcc
     6301 ggcaaattgc tcaagaacct ttgaataatc aaatgtaata tgtgacatta ttttactccc
     6361 ttaactttta aagtttcatt agtatcataa ccttttctat tcaatatttc aatgtttttt
     6421 atttttgggg agggtggcct gactttaacg acatgaggat catttctgtc taaaagcagc
     6481 tttgtgatga gcctagcgct tccctatctg cttctactat agcttactgg ggctgatccg
     6541 ggtgatgtgg tagcctcttg gcatagcc
//
LOCUS       DARYUW010000083         6177 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYUW010000083 DARYUW010000000
VERSION     DARYUW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6177
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(37..1368)
                     /locus_tag="TVW11_001825"
     CDS             complement(37..1368)
                     /locus_tag="TVW11_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1365896.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TVW11_001826"
     CDS             complement(1459..2238)
                     /locus_tag="TVW11_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1365897.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TVW11_001827"
     CDS             complement(2269..2913)
                     /locus_tag="TVW11_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1365898.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TVW11_001828"
     CDS             complement(2919..3569)
                     /locus_tag="TVW11_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1365899.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TVW11_001829"
     CDS             complement(3584..4774)
                     /locus_tag="TVW11_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1365900.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TVW11_001830"
     CDS             4966..5868
                     /locus_tag="TVW11_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1365901.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
BASE COUNT         1885 a         1423 c         1082 g         1787 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcact
//
LOCUS       DARYUW010000084         6109 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYUW010000084 DARYUW010000000
VERSION     DARYUW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6109
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..1058
                     /locus_tag="TVW11_001831"
     CDS             <1..1058
                     /locus_tag="TVW11_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1365902.1"
                     /translation="DGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNF
                     LEEQQLFERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIR
                     FKVDGHTIKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSL
                     DDTNIINAAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMK
                     ATDEIEDEKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKT
                     ATFLGYGRWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNT
                     LINLFNSFDSIYRFKED"
     gene            1061..4156
                     /locus_tag="TVW11_001832"
     CDS             1061..4156
                     /locus_tag="TVW11_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1365903.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            4324..5775
                     /locus_tag="TVW11_001833"
     CDS             4324..5775
                     /locus_tag="TVW11_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1365904.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT         1953 a          974 c         1321 g         1861 t
ORIGIN      
        1 gtgatggtaa tagcattaag cacattttat atttcaattc atatacggag gatcttttta
       61 cgtgggataa tgatttggaa aacgatgaag atcgatattt gatttatgat aaacgaactt
      121 attttggaaa tttccttgaa gagcaacaac ttttcgaacg tgctgtagac aattttcaaa
      181 agtatgttgg tagatctatt gatattgagt tccaagatgt tattgaaaca gttaaagatg
      241 agttcggaaa tgttcaaaaa gataataggg gtgaggcact aacaattagt aataaaaaga
      301 gtataagatt taaagtagat gggcatacaa taaaggtgtc tagaggagaa gagaggattt
      361 ttgtttggtc agttttctta acgctccttg aaattattat tgaagatttg actgagtctg
      421 ctgatacctc agaattttca aaaatgaact atatctatat tgacgatcct atatcttctt
      481 tggatgatac taatattatt aatgctgcaa tttatttgag tgatgttata ggtagtgctg
      541 aaaatactga tttgaaattt gtcgtctcta ctcatcaagc attattttat aatgtacttt
      601 ataatgaaat ccgatttgat agaagaatca agaaaaaggt tttttacgtc atgaaagcta
      661 ctgatgaaat tgaggatgag aaacaattta aatatttgtt gacagatgtt gaaggggatt
      721 ctccatttgg atatcatctc agagtgagag aagaattgag aaaagcaatt caagatgaac
      781 aggtagagaa attccatttt gctcttttta gaaacctagt tgaaaaaaca gcaacatttt
      841 taggatatgg acgatgggaa aatatcttgt taggtttaga tgttgctgga catgttataa
      901 catctgaaaa tattaaactc tatacacaac tgattgattt atacactcat aataggcatg
      961 ctgatttaga atatagagaa ttgcctcccc aagagaaaaa tactcttata aatttattta
     1021 atagctttga ttcaatctat cgatttaaag aggactaact atgactgaaa tcatccaaac
     1081 agatactatt ttagaggcta agaacttcat tgtactggaa aaatacacca agttggaaaa
     1141 gcctagcacc tatcagacgg aagcagactt ggagcgagag ctggttagcg atttgcggca
     1201 gcagggatac gagtacctca acaatctgac gaccccagaa gctctcttag ataacctaaa
     1261 gacccagatg gaagccctta atggcgtggt tttttctgag gcagaatggc tgcgtttttt
     1321 agaggagtac ctcaataagc ctagtgatgg tttgattgac cgcacccgaa agctccacga
     1381 taaccacatc tacgacttta tctttgacga tgggcatatc caaaatattt atctctggga
     1441 taagaaaaat atcagtcgaa ataagcttca ggtcattaac caaatgtctc aagttgggac
     1501 ttcaagtaac cgttatgatg tgaccatttt ggttaatggg ctacccttag tacaaattga
     1561 gcttaaaaag cgtggggtgg ctattcgtga ggctttcaac caggttcacc gttacagtaa
     1621 ggaaagcttt aatgaggaaa attcgctctt caagtatctc cagatttttg tcatttcaaa
     1681 tgggacggat actcgctatt ttgctaatac cactaagcga gagaaaaatt cttttgactt
     1741 taccatgaat tgggcactaa aaaataatga gccaatcaag gatttgaagg attttacagc
     1801 gaccttcttc agtcagcaga cactcttaaa cattctcatc aactactcag tttttgatac
     1861 tagtgatacc ctcctaatca tgcgtcccta tcagattgct gcgacggagc gcatcatctg
     1921 gaagattcgt tcggccattg atagcaaaat caagagtggt cctgagactg gcggctatat
     1981 ctggcatacg acggggtctg gtaagacctt gaccagtttt aaggctgcga gactggcgac
     2041 tgagatggat aaagtggaca aggttttctt tgtggttgat aggaaagact tggactacca
     2101 gactatgaaa gaataccagc gtttttcacc tgactcagtt aatgggtcaa atagcacagc
     2161 tggacttaaa cgcaatatcg aaaaagatga caataagatt gttgtgacga cgattcaaaa
     2221 gctcaataac tttatgtcta gtgaagcaca gcatgagatt tacaacaagc aagtggtctt
     2281 tatctttgac gaatgccact gttcacagtt tggcgaggct caaaagcgct taaaacaaaa
     2341 gtttaagaag tattgtcagt ttggttttac aggcacgccg attaaagttg aaaatgcttt
     2401 aggcagtgag acgacagctt ctgtattcgg tcgggagctt catgcatacg tcattactga
     2461 tgctatccgt gaccaaaagg tgttgaaatt taaggtggat tataatgatg ttcgtccaca
     2521 gtttaagtcg ttagaaactg agcaagattt agggaaatta tctgctgctg aaaataaaaa
     2581 agccctactt catccaacac ggattacaga gatttcggct tatattttag aacattttaa
     2641 tcaaaagaca cataggcaaa acggtaaagg atttaacgct atgtttgctg tgtcaagtgt
     2701 cgaggcggcc aaggcttact accaagagtt gcaagaccaa caagctggaa aagctaaacc
     2761 attgaagatt gcaaccatct tctcttatgc agcaaatgag gagcaggctg cgattgggga
     2821 gattgatgac gagactttca gccctgctga cttgtcagat attagtagta aggaattttt
     2881 gagcggagcg atttccgatt ataatcgcct ttttcagact aattttagta tcaatggcaa
     2941 tgagtttcaa aactattacc gtgatttagc taagcgagtt aagtctggag aagtggattt
     3001 gctgattgtc gttggtatgt ttttgactgg ttttgatgca ccaaccttga atactctttt
     3061 tgtggataaa aacttgcgtt atcatgggct tattcaggct ttttctcgga cgaatcggat
     3121 ttataatgcg acaaagacat ttggaaatat tgtaactttc cgtgatttgg agaaggctac
     3181 gacggatgct attaagttgt tcgggaagac ggagacggct gatattctgt tagagcgctc
     3241 ttacgaggac tacatgaatg gctacattga ggctggtcaa gagcaaaaag gatatttgga
     3301 agtcgtaaaa gaattgcagg agagatttcc agatccaacg actattatca aagaaagtga
     3361 taagaaagaa tttgtgacct tgtttggtca gttcttgcgc ttggataata tcttgcagaa
     3421 ctatgatgat ttcatgagtt tgcaggcttt gcaagagtta gatgttacag atatagaggc
     3481 tttggcagat ttcaaaggac gttttcattt ggatgacgaa gcagttgcag tactctctca
     3541 actggacatc ccaagtgttc gtgagattca agattatcgc tccgcttaca atgatatcaa
     3601 gtcttggtat gacaatgagc ggcgtaatca gcagaataac gattccgaaa tcgactggga
     3661 tgcggttgtc tttgaagtgg agttgttgaa atcacaggaa atcaatctgg actatattct
     3721 ggaattgatt tttgaaacca accaaaaggt atctgacaag gatcaactca ttgaagaaat
     3781 tacacgaact atccgtgcta gtctgggtca gagagctaag gaaagtttga tcgtggattt
     3841 tatcaatgcc agtgacttgg acagtttttc tgagaagtca gatatcttgg agcaatttta
     3901 tacatttgcc cgtcaaaaac aaaaagaagc agtggctaat ttgattgaga ctgagggatt
     3961 gaatgtagag agtgctagcc gctatattca gatgtcactc aaacgagagt atgccagtga
     4021 aaatggtaat gctctcaatg aagcacttcc taagatgagt ccgctcaatc ctcaatatcg
     4081 taccaaaaag cagatggtgt ttgaaaaaat tgtggatttg gtggagatat ttaaggggat
     4141 tggtggagaa atttaattat tattatttct tctagatata gaagagataa actttaaatt
     4201 agagcttgaa attttaagaa atattaaggc atcatatcag tagtataaaa agctgactta
     4261 taatttattt ggaaacgaca gttaatccta aaatacgatg cttgatatgg aggaggctta
     4321 aacttggaaa ataaaaagga tttaattcaa accttagcct actaccaatt ctcactagaa
     4381 aaccaatact tggatagaaa atcagcacga aagaagccgc aagaattact caagcatctg
     4441 attgcttttg ccaatgcgga cggcggtcag ttggttattg gtattgaaga tgagaagcag
     4501 gacaatatta tcactggttt caaggatggc agagcttatc ccatagacga tttcaaaaaa
     4561 attgaccatg agatgcggga gactcctctg gatttgtctt tagaggaaat ccctgtgcta
     4621 aatcataagg gagaagatga cctgattttg gttatttctg ttgaattatc gtcgaaccga
     4681 gtgattgctg cgcctaatga tgaggtttat ctgcgtcagg gcgatgaatc ggttaaatta
     4741 agctatgagc aacgtactca gcttagctat gataagggcc aacgtttctt tgaagatgaa
     4801 gtggtacctg atgcgacctt ggaagatatt gatgatgggt tagtccagga cttcaaaaat
     4861 cggtttgata tttcagagcg ctccatggaa gaagttctta aagcaagacg attcttggtt
     4921 aatggtaaat taactaaggc agcgattcta ctctttgcca aatatccatc agcgtttttt
     4981 ccacaagctc gtgttcgttt tcaacggttt gacgggacgg atatgggaac aggcagtagc
     5041 tttaatgtta ttaaagaagt aacttttgat gatgctctgc ccaccttaat tatcaaagtg
     5101 cgagatttta tccgtactca gctgcgtgaa tttcagtact tagacgataa tgggcaattc
     5161 cagattttgc ctgagtatcc tgaatttgct tggtttgagg gtgttgtcaa tgcggtgact
     5221 caccgtgatt actctgtcta tggggatcac attcgtgtac tcatgtttga tgatagactg
     5281 gagattcata gcccagggaa attaccaaat atcgttaccg ttgacaatat caagcatgaa
     5341 tgtttttcta gaaatcctcg gattgcgaga accctgactg aatttggatg ggttcgtgag
     5401 atgaatgaag gagtgaagcg tatctattct gagatggaat cagcttttct tcatgaacct
     5461 aaatatttag aaccaggtaa taaggtagtt ttgacccttg aaaataacat cgtgagtcga
     5521 catctccgaa cacgagatag tttggaaaaa caattttctg attttggaaa tctgactgca
     5581 gatgaacaag ctatcgttca ctacatgtat aattctggcg ataaaatgac aacagcaaag
     5641 gcgattgagt tgacagggag aagtcgttcg tttgttgtca aaatgctaca tcatcttcgt
     5701 gatttagaaa tcatcacttg gtttggttca agtaaaaatg accgtaatca atattatctt
     5761 ttagttgata aatgattgca gccaggatac ttattagtaa taagaataca gtagaataca
     5821 gaaaaagtgg tgttccataa aatattgatc accacttttg attatagaag tttaaataaa
     5881 gtggatattt gtatatagtt cacaatatat acctcaaata caataagaaa tagtggttat
     5941 atttttctgt tattgtagat atttaaaaat agttgataag tgattacatt tagcatctct
     6001 caactgataa attccgaaaa catacttatt tttagtaaac taatggcaag tttgcaaatt
     6061 gctttatatt gctaagtcac tattgatttg ttataatctt gttatacat
//
LOCUS       DARYUW010000085         5845 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYUW010000085 DARYUW010000000
VERSION     DARYUW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5845
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            370..2010
                     /locus_tag="TVW11_001834"
     CDS             370..2010
                     /locus_tag="TVW11_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1365905.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGEKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(2254..2943)
                     /gene="rplA"
                     /locus_tag="TVW11_001835"
     CDS             complement(2254..2943)
                     /gene="rplA"
                     /locus_tag="TVW11_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1365906.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(3049..3474)
                     /gene="rplK"
                     /locus_tag="TVW11_001836"
     CDS             complement(3049..3474)
                     /gene="rplK"
                     /locus_tag="TVW11_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1365907.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            3710..4507
                     /locus_tag="TVW11_001837"
     CDS             3710..4507
                     /locus_tag="TVW11_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1365908.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            4662..5012
                     /locus_tag="TVW11_001838"
     CDS             4662..5012
                     /locus_tag="TVW11_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1365909.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(5341..>5845)
                     /locus_tag="TVW11_001839"
     CDS             complement(5341..>5845)
                     /locus_tag="TVW11_001839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365910.1"
                     /translation="LQTKRIFFFSVVALTILTISDQKVNASQYRWRQYYYRMSPTERE
                     LKKEKEVLRNFIATIKLSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNK
                     VEIVSSLIDEHFPEGHSRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTR
                     KKLWYIQ"
BASE COUNT         1872 a         1203 c         1095 g         1675 t
ORIGIN      
        1 aagccagaag gctacaaata agcaaatcgt caaaatcatg aacacttcag gcttgctgag
       61 gaatattttc taatggttat tagaaataat gaacaattac ctaacaaaag actccaaaat
      121 aaaggtaaaa gacgaacatt caccttgctg ctcagctacc aagacaaaca atcctgatag
      181 catcaatttt ctttaggctc ttagcaatta gttgcaatat cagataattt tgaatttaat
      241 taaaaaaaac gaaactacgg agaccaatta tcagaaagct attcacagcc agcaaagggc
      301 atgctaaagt attatctgga aaaagaaagg cttaggaatg attatttcta aactaaaagg
      361 agagagacaa tgaaaaaaac aatgaagaag atgctagcag cctcgacgct ctgtatcatc
      421 atgtcaggca gcttcatcag cggctcagct agagtgttag cggaggaata ttatgggtgg
      481 aatgatgtca ctgggtctaa gtcaccattt cctctatacg tgacaccaaa aaatggagat
      541 aaaaatataa aagttcaaca aacggttgtt tactgtttta acagggatgg gcaatggcca
      601 gaaaattggg aaaaacggat atatgaatct cctgataaag ttccacataa attacccgaa
      661 tataataaaa agtcaggaag cgataatctg tttcaattac ttaatcccaa aattaagata
      721 aaaaatccaa tggcagcttt attagcggtt ttggaagatg gatatcctac gtcatcttct
      781 tcaggagtaa atcaaagaac aactcagcta gctatttggc attttacaga tggattaagc
      841 aatcttgccc aatttcatct tactccggaa gaaacttcag cttataacaa gttgatagaa
      901 aaagggacaa atgcttctaa tcaaagtgaa aataaactat taaataaaac tttagatatt
      961 tattcctata tagatgggac tggtgataag aaacacaatt atcaacacct tcttggctcc
     1021 actccaattc ctattgataa ttctaaagaa aataaatgtc aatgtacaaa agttgactta
     1081 atgcgaactg gagatggggt taaaatcatt gtttatgttg ataacaacgg aaataataga
     1141 tatgacaacg gcgacaaaat gctaaaagaa gaaactatca aacatggtca acgcggacct
     1201 gctggtgaat ctgggaaacc agggcctaaa ggggatcgag gagaaactgg agcacgcggg
     1261 ccagctgggc ctcagggcaa acctgggaaa caaggaccta gaggtgataa aggagaaacc
     1321 ggagaacggg gacctcaagg ggaaaaaggt gaacctggaa ctcctggtcc taaaggagaa
     1381 gacggtaaag acggggctcc tgggcgtgac ggacaaccgg ggcctaaggg tgaaaaaggt
     1441 gaccctggaa aagacggaca agatggaaaa ccaggggaaa aaggagaacc tggaattcct
     1501 ggtcctaaag gagaagacgg taaagatggg gctcctgggc gtgacggaca accggggcct
     1561 aagggtgaaa aaggtgaccc tggaaaagac ggacaagatg gaaaaccagg ggaaaaaggt
     1621 gaccctggac gcgatggtaa agatggagaa aaaggcgaac gcggtgaaca agggcctaaa
     1681 ggagaacgcg gtgagcaggg acctcaagga gagcgtgggg agcaaggacc tcgtggggaa
     1741 aatcatactc ctaccccaga cccaatgcct gagccggcac ctaaaccaga atccaaacct
     1801 gaacctaagc cgacacctca accagaggtt aagcctctgc cagagactaa acctcaaaaa
     1861 ccaaccaagc cgtcagcaat ggctagccaa ccaagtagca aagcactacc aaaaacaaat
     1921 gacactagcg gcttaatgac tgtacttgga acaggcttgc tctctcttct tggattaggc
     1981 ttcctggcaa aacgcaaaag aaagcaataa ctaacacata atcattagta atccattcat
     2041 tatccattta caagttatca taaaaaagcc ttatcattcc ttgactggta tgataaggct
     2101 ttttgtttac cctatatagc tctaccctta ctccaaaaat cacttaaccc taggaaaagg
     2161 ctgactatca tttttggcca aaaaaagaca gacaccaatt catgatgtct gtctcaaaac
     2221 caatcccttt tagggtcagt ccttaattac ttattaaaat gaacttggat ctaccttgat
     2281 acccacacct tgtgtagttg tgatagatac gttagtcatg taagtaccct ttgcagtagc
     2341 tggcttagcc ttaaccatta cctcatggaa agccttaaag ttttcaacca acttgtcagc
     2401 gtcaaatgat actttaccaa tgatagcttg tacgttacct gctttatcag cacgataggt
     2461 aattttacca cccttagact cttcaaccgc cttagcaacg tccattgtta ctgtaccagt
     2521 tttagggttt ggcatcaagt tacgaggtcc aaggacacgt ccaagacgtc caacaatagc
     2581 catcatatct ggtgttgcaa taacaacatc aaaatcaagc cagccgccat tgatcttagc
     2641 aacaaggtca tcttcaccaa cgaagtctgc accagctgcc tttgcttctt cagcttttgc
     2701 tccacgagca aaaacaagga cacgctgagt tttaccagtt ccgtttggca acaccatcgc
     2761 accacgaatt tgttggtctg ccttgcgaac gtcgatgttt aagttataag caacttctac
     2821 agaagcgtca aattttgcga agttagtttc ttttgcgagt gctacagctt cctctacact
     2881 gtatgccttt gtgctgtcca ctttttcaag tgctgcacgc atttgtttgc tttttttagc
     2941 catttttatc ttctccttgt aatgtggtca tatcgatttg atttaaaaat ctcccacgtc
     3001 actcatctct atgatgaagt cttgcgggta ataagggcag gttgctgatt aatcagtaac
     3061 ggtgaatccc atagaacgag cagtaccttc aatcatacgc attgcagctt caatgtttgc
     3121 agcgtttaaa tctggcatct tagtttcagc aatttcttgt acttgtgcac gagtaactgt
     3181 cgcaacttta gttttgttag gtgtacctga tcctttttca acacctgcag ccttctttaa
     3241 aagaacagca gctggtggtg tctttgtgat gaaatcaaat gatttgtctt cgtaaactga
     3301 gataacaacc gggataatca taccagcctg atcagctgta cgagcattaa attccttagt
     3361 gaatcccatg atgttgatac ctgcttgacc aagagctggt ccaactggtg gagctggtgt
     3421 cgctttacca gcagggattt gaagttttac aagtttttcg acttttttag ccatttttaa
     3481 aaatcctcct gttgtggttt tggcggtaat tcacgatttt tacctcccac aggtatgcta
     3541 gagcatacct taccattata ccttattaga cagataaatc aagtcatttt cacaaaaatg
     3601 ttaccgcaaa tagcagatgt ctcctatggc actagcagta caagcatgtg aggcttccaa
     3661 ggagccgctt ctagttgact tttaagcgtt tttttattat aacaaagcta tgcataagaa
     3721 agttacgatc aaagatgtcg cacgcgaggc gggagtttct gtggctactg tctcctatgt
     3781 catcaataac agagaagatc aaaaaattag ccctgaaacg cgcaataaag tgctgcaaat
     3841 gattaatctt ttaaattatc ggccaaacca agccgcaaaa tcactcgtga cacaaaaaag
     3901 acagctaatc gccctttact acaaagagca cagctctgtt ttaaaaagag cagagcagct
     3961 tcactttatc acccagctat ctgcctttct ttacacaaag cactatcact tgatttgcct
     4021 taatcaagaa tacatcggaa aatatgatgt agcagatgtc attctcaccc tagaggtcac
     4081 caaagaggaa ttttacaaga tcggaaatag caactttgtt cctttgattg ctattgatag
     4141 tattattgat gatcccttat ttttccagat taatagtgac cctcatctcc tgttcaataa
     4201 agccagtgct tattttgcag gggagccctt tgaactggtt agcctgccta ttcaaaacca
     4261 agaaatcact caaggactcg ctcaacagtt tgataacatt tgctggattc actctatttg
     4321 cgacatcgaa agcgtgtcta aggggaatat tctagttatt gatgatactg tcaatcatat
     4381 tcttagtaag cacaagaaca aactatacct gccaagtatc tcagaagcta agcttctgaa
     4441 gctttttcag gctattgagt gggcttccaa aagagaagca atcaacaatc ataatatttt
     4501 ggtttaacca tgataagagc ttagcaacaa gcttgctgct aagctctttt tgttggtcaa
     4561 gaggccaact ttatttaggt atcagtcagt gtgccagctc ttttagccac taaaagcagg
     4621 aattagttta caagtctacc aattgggtat aaaatagact tatgatcatc tacaaattaa
     4681 cagccttagc ctttattatc ctgactccct tattctctat gataatgata tccctattga
     4741 gactgggacg aagaggcctt aaatttcctg atttagcctt accacttttt gtttttgaaa
     4801 ttgttattgt atcaggaaaa tttttcaccc atcatttact accttattac ctgattgtta
     4861 tgtccttgtt ggccattgtt atggcactct tactgattat cagaatccag cagttttctt
     4921 accgccgatt tttcaaacta ttttggcgag taggcttttt agtcacacta ctcttttacc
     4981 tgatgctagt tggtcttatt tttatcgttt agtgccttac cagacatggc ttcaagccta
     5041 gcagtctgaa tctgccaatt aactctagca ctatcactca aaaggaagct gtctttgaac
     5101 tttctgcttg agtgggactt ttttcaaagc aatcaatcca tatcaaacca gcattagagc
     5161 atgcggcttg atacggattg attgctttaa gaactgttgt aaaatatcaa aaattcagtt
     5221 tttaataaag tccattagct atttctacac taaatatcat ttaagaaaac agaggctaat
     5281 aactagagtt cactataacc taaaatcacc aatacctccg attaacttaa tttaaccaaa
     5341 ctactgtata taccaaagtt ttttacgtgt cattataata cgttcagata aatcatctaa
     5401 tgcacgatct ttgttgagac caacatcata ttgaataccc attaatctat ctagaaactc
     5461 aagacgatat ttcttcataa tatttcgtga gtgtccttct ggaaaatgct catcaataag
     5521 cgaacttaca atctcaactt tattactaat tttaaaatag cgacttttca aagattgtaa
     5581 ttcttcttta attgctctta atttagaaaa actatctgct ccataaacct tagcttccat
     5641 ttcattagcc tcagaataac ttagttttat tgttgcaata aaatttctaa gtacttcctt
     5701 ctctttttta agctcccttt ctgtcggact cattctatag taatattgac gccaacgata
     5761 ttgagaagcg ttgacttttt gatcacttat agtcaaaata gtcaatgcta ctacactaaa
     5821 gaaaaatatt cttttcgttt gcagt
//
LOCUS       DARYUW010000086         5679 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYUW010000086 DARYUW010000000
VERSION     DARYUW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5679
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            132..824
                     /locus_tag="TVW11_001840"
     CDS             132..824
                     /locus_tag="TVW11_001840"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1365911.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
     gene            825..4376
                     /gene="smc"
                     /locus_tag="TVW11_001841"
     CDS             825..4376
                     /gene="smc"
                     /locus_tag="TVW11_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1365912.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGISKVVSVKLKDTQDLTYLS"
     gene            4741..5184
                     /locus_tag="TVW11_001842"
     CDS             4741..5184
                     /locus_tag="TVW11_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365913.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            5186..>5679
                     /locus_tag="TVW11_001843"
     CDS             5186..>5679
                     /locus_tag="TVW11_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365914.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIV"
BASE COUNT         1711 a         1045 c         1432 g         1491 t
ORIGIN      
        1 tagcagcagt caatagctcg tgcctatttg gtacaatatt tctgaaaaat ccacttgtga
       61 taagcctttc aagtggattt ttgttataat agaatggttt ataaggacat tagaaaagga
      121 gatttgtcat gatgaaaaag cttgaggccc tgctggaaaa ctcttttaat atccgttttg
      181 atgataaaag attactagag actgccttta cacatacctc ttatgctaat gagcatcgcc
      241 tcctaaacat ttcacataat gagcgtttgg aatttttagg agacgccgtt ctacagttaa
      301 ttatttcaga atacctcttt gccaagtatc ctaagcagac tgagggtgat atgtcaaaac
      361 tcagatcaac gattgtcaga gaggaaagct tagcaggctt ttcacgctat tgttcgtttg
      421 atgcttatat taagcttggc aggggcgagg aaaaatcagg aggccgtcat cgtgatacga
      481 ttttaggcga tttgttcgag gcttttttgg gtgctcttct tttggataaa ggcattgaag
      541 aggttcgtcg ctttttaaat caggttatga ttccacaggt tgagcaggga acttttgaga
      601 aggtcaagga ttataaaacc tgcttgcagg agttgttaca ggctaagggt gatgttgtga
      661 ttgattatca ggtgattagc gagactggac cagctcatgc taagcaattt gaggtagctg
      721 tattggttgg tgaggatcat cttagcaagg ggacaggtag atctaaaaaa ctggcagagc
      781 aggacgctgc taaaaatgcc ctggcccaac ttagtgaggt ctaaatgttt ttaaaagaaa
      841 tacaaatgca gggctttaag tcttttgcag ataagaccaa gattatcttt gataaggggg
      901 tcacagctgt tgtagggcca aatggctctg gaaaaagtaa tgtgacagaa agccttcgtt
      961 gggcacttgg tgaggccagt gccaaaagcc tgcgcggtgg caagatgcca gatgtgatct
     1021 ttgctggaac tgagcatcgg agtcccttga attatgcaga ggtggctgtt gtcttggata
     1081 attcagatgc ctttattaag aatgctcaga aagagattcg tgtggagagg catatctatc
     1141 gcaatggcga cagtgattat ctgattgatg gcaaaaaagt taggctaaga gatattcacg
     1201 agctgtttat ggatacagga ctagggcgcg attcgttctc tattatttct caaggtcgtg
     1261 ttgaggagat tttcaatagt aagccagagg aaagacgggc catctttgaa gaggcagctg
     1321 gagttttgaa atacaagacc cgcaagaagg agacgcaaac taagctaaac caaactcaag
     1381 ataatcttga ccgcttagac gatattatct atgagcttga gcatcaagct ggtcctctag
     1441 aaagacaggc gaaaactgct aggcaatttt tagccttaga tgctgatcgt aagcagctgc
     1501 agctggatat tttggtcaag gatatagagc aagaccgcat ggagcaggag gctcaagaaa
     1561 aggccttagt agctcttcgt gaggatctag cggcctatca taggaagcgt cagagtctag
     1621 aggcggaaaa tcaccgtcta aaaaccaagc ggcaaaagct ctctgctgta gctgagcaga
     1681 cgcaggctga tttgctagaa ttgacaaagg tcatatcaga tctggagcga cagattgacc
     1741 tcatcaagct ggaccttagt caaaagcagg aaaagaaaac agaagccagt cagcgcaggc
     1801 agcaggctca ggagcaattg cttgcctttc aacaggagca tcagcaaaag agtcgtcagc
     1861 tagatgaaat ccatcaagcc ttagctgagt ttaataccaa ggtcagcgag ctttctcagg
     1921 agcttgagcg attttctagc gatccagatc agctgcttga ggctcttcgt gaggattttg
     1981 ttggtctgct ccagcaagag gctgatgtgt caaaccaatt aaccgctatt gtagcgcagc
     2041 tggataagga aagtcaggcg aaagccagtc aggcgcagga ataccaagtc ctacaagaga
     2101 aggtcaatca gctcagtcag gacacccaga ctgctctttt ggcttatcaa gctagtcaat
     2161 caagacttga gcagctccta gctgattatc aagagctagc aaagacagtt gaggccttgg
     2221 agcaggatta tcatcaggga cagacaaggc tttttgattt gttggatcag aaaaaagcca
     2281 aggaggctcg tagggctagt ttggtttcta tccaaaaaaa tcatagtcaa ttttacgcag
     2341 gtgttagggc agtgcttcag gctgctggta agctagatgg tattttagga gcagttagtg
     2401 agcatttgac ctttgatagt cagtatcaaa cggcacttga gattgctttg ggagctagta
     2461 gtcagcatat tatcgtggca gatgaggcag cagccaagcg agcgatagcc tttttaaagg
     2521 ctaatcgtca ggggcgtgcg acctttttac ctctgacaac gattaaggcc cgtcagcttt
     2581 ctgaggtgac tctcaagcag ctcagggctt gtcagggcta tttaggcaca gctgattctt
     2641 tggtgaccta tgagccctct ttggtcgcta ttgtacaaag cctgttaggt gtgacggcta
     2701 tttttgatac cattgatcat gctaatcagg cagctaagca gctgcattat aaggtcagga
     2761 ttgtaacgct tgatggtacc gagctgcgtc ccggtggtgc cttttcaggg gggactaatc
     2821 gtcacaatag cacaaccttt atcaagccag agctagagca gattgagaag gaattagcct
     2881 tgctttctga gcagatcaag gaatctgaaa aagcagtagc tgctgtacag gctgatttga
     2941 aggctaaaaa ggctgcgcag gctgatacta agctggctgg tgagcaagca agactggtcg
     3001 agcaaaaaac acaattggcc tatcagcagc tagcagaaaa gctggctgac tcaaaagagc
     3061 tgctagagct tctcagcaac cgtcagactg gtcagtctag tgagcgctta ttatcagaaa
     3121 aagcgaggct ggaggaggca ttgcagctcc tagctgatga aaaatcagcc ttaacgtcag
     3181 aaattgagca aattaaggaa aataaagata cgattaagca aaagaaggac cagcttagcc
     3241 aggaattatc tcaggctcgt cttaaagagc gagatttgct caacgagaaa aagtttgaag
     3301 cagctaacca gcgtcgcttg gagacgatga ttgctcaggg tcagaaggaa ttagctaatt
     3361 tggagactgt tttatcacat caggttagtc aggaggccat tgaccaattg cctcacctag
     3421 aaaatcagct gacagaggct aatcaagaca agatcaagac tcaggagcgc ttcattcagc
     3481 tgcgctttga aggtgaggac tatgacgcca gactggagga gctagaggct caattgctta
     3541 aggaagccaa gaaaaatgaa gcgttcattc gtcagcaggc aagactggag gctgacttag
     3601 agcaggttat tggtcgtttg cggcagcacg ctagaagcct atcagaggag cttcagctaa
     3661 gcttagagga ggccaaggag caggcaagcc caatcaatga cactgacatg gcagcagcaa
     3721 gacagaaatt gcagcaggtt cagcaaagca ttcgtgccct aggcccaatc aatagtgatg
     3781 ctattgctca atttgatgag gttagtgagc gtttggcctt cttaaatggt caaagggctg
     3841 accttatcaa ggccaagaat ctcttggtag atacgattgg caatatggac catgaggtta
     3901 aggcacgctt tagggttacc tttgaggcta ttcgtgatag ctttaaggag acctttaggc
     3961 agatgtttgg cgggggctca gcggacttga tgttgacaga gactgatctg ctttctgctg
     4021 gagtagatat ttcagtgcaa ccgcctggta aaaagcttca atctttgaat gtgatgtctg
     4081 gcggagaaaa agccttatca gcgctagccc ttttatttgc tattatccgc attaagacca
     4141 ttccctttgt gattttagat gaggttgagg cggcccttga tgaggccaat gtcaagcgtt
     4201 ttggagatta tctcaatcgt tttgacaagg atagtcagtt tatcgtggtt acccaccgca
     4261 aggggacaat ggcagcagca gacagtattt atgggattac catgcaagaa tctggtattt
     4321 ctaaggtagt atctgttaag ctcaaggata cgcaggatct gacttacttg tcataactct
     4381 aggacagagc ttagttttag ctgtatttct acatgtagca gatgataacc aagaataagc
     4441 tataaaaaaa cctatcgtca tggtaggttt tttggctttc caaaggacaa agcacaagga
     4501 ttggctagca gtaagctgct gtttttgaca tgctcctgga acttagtacg gcttgttttg
     4561 attaaaatat accaaaaaag taactaagga cataatatat tgacaagtag atgtctgtat
     4621 attataattt aattacaaaa tgagaataat ataaataaga tttggcgttg atttcaccct
     4681 aattagtcat gctgccttcc ttagagtgac ggacgcatag caaaagagtg aaaggaggac
     4741 atgatgacag ttaagaccaa taagcaaagg ctatggctag gcttaataat agtaatagga
     4801 gcgatcataa tggtttttcg tttgaatggc aaaagaacag aggaacaaca aaaaagggac
     4861 ttggaaacca gtattgctaa gctgctggtt catgactatg aaggggttaa agaagttaag
     4921 tttacaggct ggggacattc tcgggaaaca ggttcgtggg gaacgatagt gattataaat
     4981 ggagaaaatg aaataggctt ttcgtttgat ggcttgtcta gtcttgagaa aatacgagga
     5041 attgttactg atgatgatac agaaaagatg gaaaagcctg aaactgatac caaaccaaga
     5101 attatggata ggattgacaa gattaataaa acatctcttg taggtgttac tgtcatttat
     5161 tcaaaggaca atcaggagga ttaatatggc gatatcggat agtagttata atgagttggc
     5221 taaacaggtt tataatgtcg aacctagcaa agctaaatca aatggagacc ttgttattgt
     5281 tgctggtaaa actgtaaaag atcctatcac taaacgacaa taccgagtcc tcttagttca
     5341 ggacaataac aacgatgccc ataaaaccaa tgacaacggt atgcaggcaa tggctgtagc
     5401 ccctattgtt aaaggtgata tcgatacctc tcaggttgtg attgcctatg cagggacaaa
     5461 tgctgcggat tccagagatc ttgatacgga ttggcagctg ctcattcggg gcaatcaaga
     5521 tgatttagtc agcggcaata ttgatggtgg caattttgtt attgccgaaa accaattacg
     5581 atctgctcaa aagttttatc aacaggtcaa aagaaagtac cctcattctg ccttaacaac
     5641 cacaggtcac tctctcggag cttatctagc actaatagt
//
LOCUS       DARYUW010000087         5632 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYUW010000087 DARYUW010000000
VERSION     DARYUW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5632
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVW11_001844"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVW11_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1365915.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TVW11_001845"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TVW11_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         1611 a         1261 c         1065 g         1695 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt actctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc at
//
LOCUS       DARYUW010000088         5467 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYUW010000088 DARYUW010000000
VERSION     DARYUW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5467
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(150..389)
                     /locus_tag="TVW11_001846"
     CDS             complement(150..389)
                     /locus_tag="TVW11_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1365916.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TVW11_001847"
     CDS             complement(548..1036)
                     /locus_tag="TVW11_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1365917.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TVW11_001848"
     CDS             complement(1055..1345)
                     /locus_tag="TVW11_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1365918.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TVW11_001849"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TVW11_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1365919.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5467
                     /locus_tag="TVW11_001850"
     CDS             4640..>5467
                     /locus_tag="TVW11_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1365920.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDTPKPEPKPEPKPEPKPEPKPEPKPEPKPGPKPEPKPEPKPGPKPGPKP
                     "
BASE COUNT         1667 a         1213 c         1099 g         1488 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatacaccta agccagagcc
     5341 taagccagag cctaagccag agcctaagcc agagcctaag ccagagccta agccagagcc
     5401 taagccaggg cctaagccag agcctaagcc agagcctaag ccagggccta agccagggcc
     5461 taagcca
//
LOCUS       DARYUW010000089         5331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYUW010000089 DARYUW010000000
VERSION     DARYUW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            90..1643
                     /locus_tag="TVW11_001851"
     rRNA            90..1643
                     /locus_tag="TVW11_001851"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1865..1937
                     /locus_tag="TVW11_001852"
     tRNA            1865..1937
                     /locus_tag="TVW11_001852"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1898..1900,aa:Ala,seq:tgc)
     gene            2245..5144
                     /locus_tag="TVW11_001853"
     rRNA            2245..5144
                     /locus_tag="TVW11_001853"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5229..>5331
                     /gene="rrf"
                     /locus_tag="TVW11_001854"
     rRNA            5229..>5331
                     /gene="rrf"
                     /locus_tag="TVW11_001854"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1525 a         1083 c         1543 g         1180 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggggg
      481 gaaccctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gttagagaag aacagtgatg ggagtggaaa gtccatcatg tgacggtaac taaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt ttgataagtc tgaagttaaa ggcagtggct
      721 taaccattgt atgctttgga aactgttaaa cttgagtgca gaaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggtctgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc cgtaaacgct gagtgctagg tgttaggccc tttccggggc ttagtgccgg
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc cgatgctatt cttagagata agaagttact tcggtacatt
     1141 ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccttatt gttagttgcc atcattaagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggttggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctctgaaag ccaatctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg ttaaggagcc
     1561 agccgcctaa ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa
     1621 ggtgcggctg gatcacctcc tttctaagga aaaaggaagc acgtttagcg tcttatttag
     1681 ttttgagagg tcttgaaata agtcatgaga acgttaagaa acccgtatga caatagggaa
     1741 ctgacgcaga gtcgtaggac tcaaggaagt gattcttttt cactagggtt ttagttcgaa
     1801 tacagtttgg cttcatacag accattgata agagtataca tatacaagta catttatagt
     1861 gtacggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1921 gatcccgcta ggctccatta tctaggatac aaagagaagt ttgggttacc taattttctg
     1981 tattctaaga tatataagat atagttcaag taattgaaca cgacctcatt ttttaggaaa
     2041 aaagataaat ctcctcgtgt gtaaagcaca catcgtcgat ttcctatttt tctacaaaaa
     2101 tgcccaacaa gttgggacgg tcttagtatc ttaatcttgt ccattgaaaa ttgaataact
     2161 atatcatatt ccgcaatcaa aaaagattgt aagaaagtaa caagaaataa accgaaacgc
     2221 tgtgataacg agtttaaaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg
     2281 cactagaagc cgaagaagga cgtgacaaac gacgaaatgc tttggggagc tgtaagtaag
     2341 caaagatcca gagatgtccg aatgggggaa cccactagct aatggctagt atccataact
     2401 gttaaggtta tgagaaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag
     2461 aaagcaaacg cgattgcctg agtagcggcg agcgaaaagg caggagggca aaccgaagag
     2521 tttactcttc ggggttgtag gactgcgctg tgggacgaca agattataga agaaggcctt
     2581 gggaagggtc gccaaagaga gtaatagcct cgtattcgaa atagtcttta accctagcag
     2641 tatcctgagt acggcgagac acgaggaatc tcgtcggaat ctgggaggac catctcctaa
     2701 ccctaaatac tcactagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2761 ccccgggagg ggagtgaaag agaacctgaa accgtgtgcc tacaagaagt tcgagcccgt
     2821 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttta tgtgcgaggt
     2881 taagttgaag agacggagcc gaagggaaac cgagtcttaa tagggcgtaa gtacgtggac
     2941 gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg
     3001 gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt
     3061 ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgatat
     3121 gaagtctctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     3181 agataaactc cgaatgccaa tgagatatga tcggcagtca gactgcgagt gctaagatcc
     3241 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc cccaaataac tgttaagtgg
     3301 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     3361 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     3421 acagtttacc gaagctgtgg attaccgtta aggtaatggt aggagagcgt tctatgtgtg
     3481 atgaaggtat actgtgaaga gtgctggaac gcatagaagt gagaatgccg gtatgagtag
     3541 cgaaagacag gtgagaatcc tgtccaccgt aagactaagg attccagggg aaggctcgtc
     3601 cgccctgggt tagtcgggac ctaaggagag accgaagggt gtatccgatg gacaacaggt
     3661 tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa ctaaaccgga
     3721 cgactggaag agtccggcta agcagtgagg tgtgatgtga gtcaaatgct tacatctata
     3781 acattgagct gtgaagggga gcgaagttaa gtagcgaagt tagagacgtc acactgccaa
     3841 gaaaagcttc tagcgatacg tatactctac ccgtaccgca aaccgacaca ggtagtcgag
     3901 gcgagtagcc tcaggtgatc gagagaactc tcgttaagga actcggcaaa atggccccgt
     3961 aacttcggga gaaggggcgc tgactgaagg tcagccgcag tgaataggcc caagcaactg
     4021 tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc
     4081 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtatgaat tgaagcccca
     4141 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     4201 ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat
     4261 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
     4321 actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga gccatagaag
     4381 tcgggacgcc agtttcgatg gaggcgatgt tgggatacta cccttgtgtt atggctactc
     4441 taacccggat aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg
     4501 tcgcctccta aaatgtaacg gaggcgccca aaggttccct cagattggtt ggaaatcaat
     4561 cgcagagtgt aaaggtataa gggagcttga ctgcgagagc aacacctcga gcagggacga
     4621 aagtcgggct tagtgatccg gtggtaccgt atggaagggc catcgctcaa cggataaaag
     4681 ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc
     4741 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
     4801 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
     4861 cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac
     4921 ttaccgctgg tgtaccagtt gtctcgccag aggcatagct gggtagctat gtagggaagg
     4981 gataagcgct gaaagcatct aagtgcgaag ccctcctcaa gatgagattt cccataacgt
     5041 taagttagta agagccctga gagatgatca ggtagatagg ttaggagtgg acgtgtggtg
     5101 acacatggag cggactaata ctaatagctc gaggacttat ccaaaagatg aaaccagtcg
     5161 ctattgacag cttaaggaat tcttgttaga ctatagttat tcaattttga gtggagaaga
     5221 ctcgtaagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagtag
     5281 ttaagcccta gaacgcctga agtagttggg ggttgccccc tgtgagatac g
//
LOCUS       DARYUW010000090         5189 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYUW010000090 DARYUW010000000
VERSION     DARYUW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5189
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..156
                     /locus_tag="TVW11_001855"
     CDS             <1..156
                     /locus_tag="TVW11_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEL1365921.1"
                     /translation="WYKSKQTDLNAAEVQDLALEMSYKEVVDGNNAAITGQWSDSPQI
                     ILDGGNQ"
     gene            153..1268
                     /locus_tag="TVW11_001856"
     CDS             153..1268
                     /locus_tag="TVW11_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1365922.1"
                     /translation="MTENIPLRVQFKRMTADEWARSDVILLEGEIGFETDTGYAKFGD
                     GRSRFSELKYLTGPKGPKGDDGPQGKTGDTGPQGPAGKPGTTDYNQLQNKPNLDAFAQ
                     KKETDSKIAKLVSSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLKFKPAATVAYSS
                     STGGAVNIDLSSSRGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYKGTTNAVN
                     IAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEASYDENAAA
                     LSIDIVKKQKGGGKGTAAQGIYINSTSGTTGKMLRIRNLNDDKFYVKPDGGFYAKETS
                     QIDGNLKLKDPIANDHAATKAYVDGEIKKIKALLTAK"
     gene            1287..3320
                     /locus_tag="TVW11_001857"
     CDS             1287..3320
                     /locus_tag="TVW11_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1365923.1"
                     /translation="MSRDPTLTLDESNLTIGSDGRVHYTFTASQDNQKVRLASNCLGT
                     TRFNQVMIERGDKATDYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNSNL
                     WSKIKLNNRGMLQTYFDTTIKNEILTTAQGIRETISDTERGLKSEFLKTVQGQRIQLE
                     SLLEQKTAQIGLTVDGLRLDLNKAGKQTASLQASIEGLRQDYQDADRQLSASYQSGIS
                     GLKTQLANDKIGLQAEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLR
                     AEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQ
                     DTEKNYSSLTQTVSGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSIINESGDSI
                     KLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFGAKLGEFIK
                     LKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKVIRARNAAM
                     MIDLSNSKIDFNSNATINFNSSNNALVRKDGTHTAFVHFSTATPKNYTGSALYASIGI
                     TSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFNIDRGFKMR
                     PSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYINGL"
     gene            3329..3760
                     /locus_tag="TVW11_001858"
     CDS             3329..3760
                     /locus_tag="TVW11_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1365924.1"
                     /translation="MDLTVQNKGLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKVAELNDFLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIILIDNILEQYEANKKGE"
     gene            3764..4375
                     /locus_tag="TVW11_001859"
     CDS             3764..4375
                     /locus_tag="TVW11_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1365925.1"
                     /translation="MRNWKVTGKYPQYDGTGAVASTHIIIAAEDGAVIPQLIKQDLTS
                     TSDTEIIKAALEEFKKAEYVEIAMGEAVQKVDDLEKLSQATAKTATTAQAAAGLAKLS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPGKKGQYQEHDVFTVVDESHEDL
                     AGEGKLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            4386..4757
                     /locus_tag="TVW11_001860"
     CDS             4386..4757
                     /locus_tag="TVW11_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1365926.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            4873..>5189
                     /locus_tag="TVW11_001861"
     CDS             4873..>5189
                     /locus_tag="TVW11_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1365927.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVVG"
BASE COUNT         1646 a         1027 c         1226 g         1290 t
ORIGIN      
        1 tggtacaaat ctaagcagac ggatttaaat gcggcagagg tgcaggattt agctctggag
       61 atgtcttata aagaggtggt tgatggtaac aatgccgcga taacagggca gtggtcagac
      121 agcccacaaa tcatcttaga tggaggtaat caatgacgga aaatatacca ctacgagtcc
      181 aatttaagcg catgactgct gatgagtggg ctcgtagtga tgttatctta ctggagggtg
      241 agattggctt tgagactgat actggctacg ctaaatttgg tgatggtcgc agtcgcttta
      301 gtgagcttaa gtatcttact ggtcccaaag gtcctaaagg agacgatggt ccccaaggca
      361 agactggcga tacaggtcct cagggccctg ctggcaagcc tggaacgaca gattataatc
      421 aactccaaaa taaaccaaat ctagatgcgt ttgcacaaaa aaaagaaact gatagtaaaa
      481 tcgccaaatt agtatcaagc aaagcagata aaagcgctgt ttacttaaaa gcagagtcaa
      541 aaatagagct agacaaaaaa ttgagtttga caggtggcgt tatgacaggc caactaaaat
      601 ttaagccagc cgccactgtt gcttattcct cgtcaacggg tggagcggtc aatattgact
      661 tgtcgtctag cagaggtgct ggtgttgttg tctattctaa caatgatacc agtgatgggc
      721 cgttaatgag cttgcggacg ggtaaagaga ccttcaatca atcggcgctt tttgtcgatt
      781 ataagggaac aacaaatgcc gttaatattg cgatgcgtca gccaaccacc cccaattttt
      841 catcggcgct taatattact agcggcaatg aaaatggtag tgcgatgcaa attagaggcg
      901 ttgaaaaagc attgggaacg ctcaaaatca cgcacgaaaa cccaaacgtt gaggcaagtt
      961 acgatgaaaa cgctgcagcg ttatctattg atatcgttaa aaaacagaaa ggcggtggaa
     1021 aaggtactgc tgctcaagga atctacatta actcaacatc aggcacaact ggtaaaatgc
     1081 tcagaatcag aaaccttaat gatgataagt tctacgtcaa gcctgacggt ggtttttatg
     1141 ccaaggaaac ttcgcagatt gatggcaacc tgaaactcaa ggatcccata gcgaatgatc
     1201 atgcggcaac caaagcttat gttgatggtg aaatcaaaaa aataaaagca ctcttaacgg
     1261 ctaagtaaat gtaaaaagga ggagatatga gcagagaccc aacattaaca ttagacgagt
     1321 caaatttaac gatcggctca gatggacgtg tgcattacac gtttacggct agtcaagaca
     1381 atcaaaaagt cagattagcc agcaactgtc taggaacaac tcgctttaat caggttatga
     1441 ttgagagagg cgacaaagcg actgactatg ttgcgcctgt tgtcgttgag ggcagcggtg
     1501 agtcgacagg tgtgtttaaa agtcttgagg agatgcttag tggtctacag tctattaatt
     1561 tagagctgac agataccaaa aactccaatc tttggtcaaa aatcaagctt aacaatcgtg
     1621 ggatgttaca gacatacttt gacacgacta ttaaaaatga gattttaaca acggctcaag
     1681 gtatcagaga gactatatcc gacaccgagc gaggacttaa gtccgagttt ttaaaaacgg
     1741 tacaaggtca gcgcatccaa ctcgagagct tgctagagca aaagacggct caaattggct
     1801 taacagtcga tggcctaaga cttgatttaa ataaagcagg caaacagaca gctagtttac
     1861 aggctagtat cgagggattg agacaagatt atcaagatgc tgatagacag ctatcagcta
     1921 gttatcagtc tggtattagc ggcttaaaaa ctcaactggc caatgacaaa atcggtctac
     1981 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
     2041 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
     2101 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcggaca gagcttgagt
     2161 cgcagatcag tggcctaaaa gcagtacagc agtcaactgc aaaacaaatc tcacaagaga
     2221 ttagagacag gacaggagct gttagtcgtg tacaacagga cttagctagc tatcagcggc
     2281 gattgcagga tactgagaag aattactcta gcttaaccca gaccgtcagc ggtctgcaaa
     2341 gcgatgtcgg ctcaccaaca ggtaaaatcc aatcacgcct tactcaacta gcaggacaaa
     2401 ttgagcagcg ggttactaga gatggtgtca tgagtatcat caacgagtca ggcgatagca
     2461 ttaagctagc gatccaaaag gctggtggga ttgatgctaa gatgagcgct aaagagatta
     2521 tctcagcgat taatcttaat ggctatggcg tcagaatctc cggtgagcgt attgctctgg
     2581 acggtaatac gaccgtcaat ggggcttttg gggctaagct cggtgagttt attaagctca
     2641 aagctgatca aatcatcggt ggtacgattg acgctgctaa gattagagtg atcaatctta
     2701 acgctagcag cattgttggt ctagacgcta actttatcag agccaaaatc gagcatacga
     2761 tcactagctt gcttgagggt aaagttatca gagctcgcaa cgcagcgatg atgattgact
     2821 tgtcaaactc taagattgac tttaacagca acgccaccat caactttaac agtagcaata
     2881 acgcgcttgt ccgtaaagac ggtacccaca cagcctttgt gcattttagc actgccacgc
     2941 caaaaaatta cacaggatca gcactttacg cctcaatcgg gataacctca tctggtgacg
     3001 ggattaatag tgcgtcgagt ggtcgttttt gcggtgctag gttttttaga tatgcacgag
     3061 gttacgagca cactgcactt gttgaccaag ctgagattta cggtgatgat attgtcttta
     3121 gcgacgattt taacatcgat cgtggcttta agatgcggcc tagcctaatg ccaaaaatgg
     3181 tcgatctcaa taagatgtac caggccattt tagctcttgg ccgctgctgg ctacacgcta
     3241 ataatacagc gtggaccttt aactcagaca ctaccagcgc aattatcaga gagtataact
     3301 cttacatcaa cggattatag gagacaacat ggatttaaca gtacaaaaca aaggcttaaa
     3361 tacgctctat agcgtactag acaaaattaa ggttactaat atgagagtaa atcgcggccg
     3421 cgctaagctg cttgccaaag tagaggctaa gctcagagag tatgccaaag acgaggttga
     3481 tattatcgat caatacgctg ctaaaaacga caaaggtaag tggttagttg atgacaaagg
     3541 caacgctaaa ttagctgatg tcacaaaagt agctgagctt aacgactttt tagacgagtt
     3601 agccaacgag cctatcgtca tcaaaggcca tgagtactct aagcgattta ttgatttttt
     3661 ggagtatttg gccgaggccg aagatgagtt tacaggggcc gaaatcatct taatcgacaa
     3721 cattttagag cagtacgaag caaataaaaa aggagagtaa attatgcgta attggaaagt
     3781 cacaggtaaa tacccacaat atgatggtac aggagcagtc gcaagcacac atatcattat
     3841 cgctgcggag gacggagctg ttatccctca actcattaag caggacctga cgtccactag
     3901 cgacacagag attatcaagg ctgccttgga ggaatttaaa aaagcagaat acgttgaaat
     3961 tgccatgggc gaagcagtgc aaaaagttga tgatctcgaa aaactctcac aagcgaccgc
     4021 taagacagca acaaccgcac aggctgcagc agggctagct aaattgtccg cagagcgcac
     4081 gcaaaagatg attaacttac aaactatcca catgttgacc agcgtcgata agatcgagcc
     4141 tgacatttac aaaggcatgc tagagcttat cgagccaggc aaaaaggggc aatatcaaga
     4201 gcatgatgtc tttactgttg tagatgagtc tcacgaggac ttggccggcg agggtaaact
     4261 tgtctttgtg tatgttaacg aggcctttac ctatgacaag caaaccctca aagatctgga
     4321 atcagaggat aaagtcacag ttatcaagta cgctgatttg gttaaaggca agtaagaggt
     4381 gatccatgtt tatttttttg agacaattaa tccagaccca agatggtaaa atcctattta
     4441 ctttaggagc aattgcagtc gcaatgatga ttgatttttt aacgggtacc gttgcagcaa
     4501 aaatcaaccc caacatcgat tttaggagca aagaggggat taatggtatt ttgcgcaaaa
     4561 tttgctcaat tgccctgatg atctttttta tccctttgtc aatcttgttg ccaaacgata
     4621 caggagtagc ctttttgtat gtcatgtacg ttggctatct gctctttgag ctaaaatcaa
     4681 tcctagaaaa tctaaacaaa atggggattg atgtagcctt gtttaagcaa tttattgata
     4741 tgtttagtaa aaaatagggg gagatatgcg agcaatcaca cgattagcaa tagtcatagc
     4801 aatcacaata ctatatttac cgctatctgt gattgctctg attgtttatc cgtttttaga
     4861 taaggaggac agatgacctt tttagatgac attaagcaag gctgcttaga tggctggaca
     4921 aagtataaaa tcttgccatc gttgaccgca gcacaggcaa tccttgagag tggttggggc
     4981 aagtacgccc cacataacgc tctatttggt atcaaggcag atagctcttg gacgggtaag
     5041 tcatttaata caaaaactca ggaggagtat cagccgggtg ttgtaacgga tattgtagat
     5101 cgttttaggg cctatgatag ctgggacgag tcgatccttg atcatggcca gtttttagta
     5161 gacaatccac gctacaaatc agttgtcgg
//
LOCUS       DARYUW010000091         4840 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYUW010000091 DARYUW010000000
VERSION     DARYUW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4840
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            1170..>4840
                     /locus_tag="TVW11_001862"
     CDS             1170..>4840
                     /locus_tag="TVW11_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1365928.1"
                     /translation="MKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNE
                     QFPDYYNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVL
                     STLIFKDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLD
                     MKNKELRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEK
                     DKAKEERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEII
                     PFRNERELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNF
                     NPVGMSRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQM
                     SLTDIFEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWL
                     NPVSKNNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIAN
                     QFIVKVDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETID
                     KKLKSYHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYL
                     GGIPPINYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWG
                     GLSDVFDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNM
                     GFESGNILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFE
                     ETTFSNNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISS
                     SGTMDKKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDE
                     EWVKLGTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAI
                     KNIKGSYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEE
                     KVRAYLGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLF
                     REDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGK
                     VNFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADE
                     YLSGNIRDKIEVIDSYIKNV"
BASE COUNT         1953 a          571 c         1001 g         1315 t
ORIGIN      
        1 atcaggttgt aaaaaaaata gataacctta ttgaaaatgg aaaatatatt caagaagatg
       61 tatatacaga gcaagaaagc ataaaaactg aggaagaata ttttgatgaa gatacctata
      121 cggaacaaaa ctctaaagaa aatgaacaag attggcaaag agaacaggaa attttgctga
      181 ttcaagatga aagagaagta tcttatgaag aggcggagga aatatatgaa aggcaagcag
      241 aaatagaaca taatgccttt gcaaccggtg tagagaataa catatcgtca actcaaagta
      301 acaaggatta ttggattgta gaatttaatg aaggctcaaa tctgatagaa aaaaattatg
      361 ccggagaagt tgttacgaaa aaattgcttg atgaaatcaa ggtgcttgac gaaaaaatta
      421 gagttcataa taagactgtc ggtgaagatg aatacggaga aatgacagat gaatgggtag
      481 gttattctaa attctatttt gaccatattg tagacgggaa agtagaagaa cacttcagaa
      541 tggatatcgg ggatggaaat gaggtaaacc aaagagattt tcaatatctt tatgagcaga
      601 ttgaaccgga aaaagaaaat aaagaatacg ggatggatag tatagatagt gtcataaaag
      661 atattttaga aaaagaatct atgactgtgg tatcaagcaa agatgattat ataaagttat
      721 ttccatattt tagaaacttt gtatataccg atggtctaag gcttgatgaa tataatccgt
      781 ttgaagatga tgaaaatatt tcggatttaa ttcgactgac ttttttccaa aataatgatg
      841 gagaatatag ggtagtctat aacaatgcgg acagtttact gtattcaagc aatgttgact
      901 attttttgga gaaaatagag gctgaaaagg taaggttaga agataatata gctgagatac
      961 cgaatgaaga taaaattgcc gttaaggttg ggaattacta tgctgttgta gaaaaagaaa
     1021 gagtaaagga tatatcctta gaagaaacag gagttcgtgt ttatccgaaa gaaaataact
     1081 ttgagggaaa aatttaccca ttgtatcgtg gcagcacctt tgaagaaagt gcaaaaatag
     1141 ataaactttt cgatgagatt gcaataggca tgaaagaggt caatttgacc gatttaaatg
     1201 atgtttttta tcttgaaaat caaggacttt atgaaatttc atcggatagg gtaacggaag
     1261 aaaaagccgg atacgatttt gaagtggcaa gttttaatga acagtttcct gattactata
     1321 atgacattta tgtatataac agaaatttaa aaatagatgg tgctaatcaa aacattgcat
     1381 atatcaatag agaaaatgaa atacatttta atgtaaatct accggaagaa gaaaaagcaa
     1441 aggtgcttga aattagagat aagaaagaag tcttatcaac tcttattttt aaagatgtaa
     1501 aggaggtcgg cgaatatcag tttcatccac aaagcgaaga atttatctta aatgaattga
     1561 gtatatctga agaaaaatta aaagcaccgg aacatataac agataagatt gataagaaag
     1621 aaggctatga ggctgaactt gttttggata tgaaaaacaa ggagttaagg cagcatttaa
     1681 gatataacgg atatatgtta agtagcaatg tggcggtttc ctatgatagt tataaagcaa
     1741 tacttaaaaa tctttcttat ctgcttgatg ataatcatag aaatattatg cttaccggct
     1801 atgtcaacga acagattgaa aaggataaag caaaggaaga aagaaaagaa cctgtatatc
     1861 aagagggaat gaatgtaagg tatcaaggca aagaatatat catttcagaa attcaagact
     1921 ataaaacata taaaacaata aagctagatg attcagaagg atatttaaac ggctttataa
     1981 cgggcagtga aattattcct tttagaaatg aaagagaact tgatttggaa atcatatcta
     2041 caacagagaa gttacaagaa caaagtataa atggtgaaga tcttattctg ttagatattg
     2101 aagaatataa caaaaaagga ctttccgtta tctttcaaaa taaagagtat gaaattacag
     2161 gaaataattt taatcctgta ggaatgagca ggttacaact tgtctcgaat acagaaaaac
     2221 tgatgacaga aatttcatat acacctcaaa gaccggtcgc aaatctttat gcaaaaaaag
     2281 atctccttga aaggtttaat ttaaatgaga aaaatagtga aaaaagtatt gaagcaaagc
     2341 aaatgtcttt aacagatata tttgaggaac aggatacaac aaagggaaaa gaagaaattt
     2401 caagtgagaa agaacgtgta cctgtcaata taggggcaaa ggtaatctat cagggagaag
     2461 aatatacagt aagtgccttt gagtataata atattttaga gaaaaatgat atatggctaa
     2521 atcctgtatc aaaaaataat catcaaattc cgattgtaag tttttctgac agagaagagc
     2581 taaatgaaaa gctcattgtt atagatacca atcttaactt aggagaagac aagtcggaac
     2641 tgttacatca tagtttagat gtaataaatg ataaaggttc tgtgattgcc aatcagttta
     2701 ttgtaaaagt cgataatcaa aacagggaac ttacagtata tagtgaacaa aatcctaata
     2761 gtcatagaga atttgaactt tcttttgatt atctaaacgg gcttgggcaa attgacggag
     2821 atggaaataa tctaaaactt acaaagcata aaaaagaaac cattgataaa aaattgaaaa
     2881 gttatcattc ttggaaagaa gatggggaaa aaagaggaat tccgggaata gcaggttctt
     2941 ctattacttc acctattact gatgaaatgt tttggcagat gaaagaatat gaagaaaaat
     3001 taaaagagga ggaaagatac gcccctgatg ataagtattt gggaggtatt cctccaatca
     3061 attacaaaat cacaaaagaa gatgaaatct tgccgccgtc cgaaaggctt aaaaataaca
     3121 tagaagccat caaggtatta aaagaaattg aggaaagaca tagtcatgca acaaaggaag
     3181 aacaggatat tttgagtaga tatgtcggct ggggtggact ttctgatgtc tttgatgaag
     3241 aaaagggagg acaatggaaa gatgcaagag aattcttaaa agaaaatcta tcaccgtctg
     3301 agtacgatgc agcaagggaa agtaccctta cagcctttta tacaccgaag attgtaatag
     3361 acagtatcta tcaagccgta ttaaatatgg gatttgaaag tgggaatatc ttggaaccaa
     3421 gtatgggaac tggcagattt ataggcaatc ttccagacag catgaaaggc agtaaatttt
     3481 atggtgtaga acttgacagt ataagtggta ggatagcaag taggctatat cctaatgcta
     3541 aaatacagat caaaggtttt gaagaaacga ctttttcaaa taatctgttt gatgtagcgg
     3601 tgggaaatgt accgtttgga gaatataaga tagttgatcg tgagtatgag aaaaacaatt
     3661 ttcttattca cgattttttc tttgccaaaa ccttggataa agtacgttcc ggtggagtag
     3721 tagcctttat aagttcaagt ggaactatgg ataaaaagag tgaagatatc agaagatata
     3781 tttcagaaag agcagagttt ttaggagcaa ttagactacc taataatact tttaaaggcg
     3841 aggcgggtac ggaagtaaca agtgatatta tttttcttaa aaagagagat cgactggtaa
     3901 aacttgatga agaatgggta aaacttggca ctgacgaaag aggactgaca tataacaaat
     3961 actttgtaga taaccctgat atggtacttg gaaatatgga agaaatatca agcagatttg
     4021 gaacaagtct tgcctgtgtt gcagatgaaa atagtactct gaaagaacag ctggataccg
     4081 ccattaaaaa cattaaagga agttatgaga agatagaatt aaataatgaa tttgaagtgg
     4141 aaaccattcc ggctgatgac agtgtgaaaa attattctta tgcagtaatt gatgataagg
     4201 tatattttag agaaaattcc gttatgcaaa aattgaattt aaataaaaat gatgaggaaa
     4261 aagtaagggc atatcttgga atagaaaaag cattaagaca ggtaattgct tatcaaaaag
     4321 aagattattc cgatacggaa attaaggaga agcaagggga gttaaatcgt atttatgatg
     4381 agttttccaa gaaatacgga attttaaaca gtaaggcgaa taaaaaactg tttcgtgaag
     4441 acgctaatta ttctttactg tccactttgg aaaagctgga taaagaagga aactttatag
     4501 aaaaatccga tatctttaca aaaagaacaa taaaaaaagc agtagccata gagcataccg
     4561 acaatctgac agaagcactt atcctatcta tttctcaaaa agggaaagtc aatttcgagt
     4621 atatggaaaa gctcactgaa aaaacaagag gagaaatcat tgaaggatta aagggagaaa
     4681 tattcttaaa tttagatgga tttgatccaa gtgatacgac tcctttttct tcagccatag
     4741 acttgggaga tttttcaaga tcttacgtaa ctgctgatga atatttatct ggaaatatca
     4801 gagataaaat agaagtaata gattcgtata taaagaatgt
//
LOCUS       DARYUW010000092         4828 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYUW010000092 DARYUW010000000
VERSION     DARYUW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4828
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..189
                     /locus_tag="TVW11_001863"
     CDS             <1..189
                     /locus_tag="TVW11_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1365929.1"
                     /translation="SYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAKDITF
                     EEVLDNGIKMVEKIKNEN"
     gene            361..2073
                     /locus_tag="TVW11_001864"
     CDS             361..2073
                     /locus_tag="TVW11_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1365930.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            2077..2628
                     /locus_tag="TVW11_001865"
     CDS             2077..2628
                     /locus_tag="TVW11_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1365931.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            2670..3416
                     /locus_tag="TVW11_001866"
     CDS             2670..3416
                     /locus_tag="TVW11_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1365932.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            3433..>4828
                     /locus_tag="TVW11_001867"
     CDS             3433..>4828
                     /locus_tag="TVW11_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1365933.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKNSNLIFSTE"
BASE COUNT         1979 a          581 c          998 g         1270 t
ORIGIN      
        1 agttatagaa aaacagaatt tgacataggt aaaatcatag acttactgga aaaattgaaa
       61 ataaatgaag cctttttgaa aagatggcaa gcttattcaa gaaaaaatct gtatgcgaaa
      121 gatataactt ttgaagaagt attggacaac ggaataaaaa tggtggaaaa aataaagaat
      181 gaaaattagc atataacggt tttacaatga aaagaaggcg tcaaacattt ttttgtaagt
      241 tagttcccaa acaggaaaat ggattaaaaa atagaaaatg aaatatataa aactttaaaa
      301 gacaattgga gaaatgcaaa ctctgattgt cttttttcat gtagaaaaaa ggaggaattt
      361 atgcaaacac tggtgataag tgaaaaaccg agtgttgcaa taagcatatc aaaggtgctt
      421 ggagcaacaa aaaagaaaga cggatataat gagggaaatg gatatagggt aagttggtgt
      481 gttggtcatt taattcagat ggcaaatccg gatgcttatg atgaaaagta tgccaagtgg
      541 gatatggctg atttaccgat tattcccaag gactataagt atgaagtagc aaaggcaacc
      601 aagaagcaat tcaacatcct taaaaagctg atgaatgata aagaaattga tacggttata
      661 aatgcttgcg atgcaggtcg tgagggagag agcattttta gacttgttta taatcaagtg
      721 aattgtaaaa agaaaatgaa acgcctttgg atttcatcta tggaagatag tgcgattaaa
      781 gagggttttg atcatctaaa agacggaaag aaatatgaca atctctttga atcggcacag
      841 gcaagagcca ttgcagattg gttagtcgga atgaatatta gtagacttta ttcctgctta
      901 tataatcaaa attactctgt cggtagggtg cagacgccaa ctcttgccat gattgtaaaa
      961 cgagatgacg agatagcaaa ctttaaaaaa gaaaaatatt atactgtaga gctatctatg
     1021 gacggtttta tactttccac agacagaatt gatgataagg tagcagcaga gcagctaatc
     1081 aatttagttg gtgataagat tgaaattacc gatgtcattc aaaatgaaaa gattacaaag
     1141 ccggatttac cttttgacct gacaacactt caaagagagt gcaataaata ttttggatac
     1201 tcagctaagc agactcttga ttatgctcaa agtctgtatg agaagaaact tattacctat
     1261 ccaagaacag acagtagatg ccttactgaa gatatgatta caagtatgat aaataacata
     1321 ttgggacaaa atgactttga tacagggcgt attaaggtca tttttaattc aagcaaggta
     1381 acggatcatc atgctattat accgacagta agttcaatga gtgaagattt attgagtatt
     1441 ccggagagtg aagcaaaagt gtatggactt atttttaata agttacacgc aagtgtgggc
     1501 tatcctttaa tcgagaatac aacaaagatt gtagtgactt ttgacggctt taaatttaca
     1561 agttccggaa aagtaattaa ggatgagggg tttactaagt atttaaagga atataagacg
     1621 aaaaagaatg aagatataga acttccaaat gtaaatatag gtgatagtct taaaatcaag
     1681 gataaagaaa tcaaagaaaa atatacgcaa cctccaaaac attttacgga aaacacctta
     1741 ttaaaaagca tggaaacagc aggaaatgac gctttaaaaa aaggtattga ggttgaaaga
     1801 aagggtattg gcacacccgc aactcgtgca gggattatag aaaatctaat ttacaaaggc
     1861 tttattcaaa gagataagaa aaatcttgta gctacacata aaggaattag tcttataaca
     1921 attgttgcag acaactttaa atctgctgaa acaactgcaa agtgggaaat ggagttgtct
     1981 gatatttctc aagggaaatc ttcaaaggaa gaatttttaa gaagagtaga agctgagata
     2041 agaaatgaat tatcccgtta taaaaaggat tagtctatgt ttgatactct aataaaattt
     2101 agtaaagaca gagaaaaatt ggatttttat gccacagata aaagggcaat tcatgaactt
     2161 ttaaaaagag agcagtttct atctcctatt tatgagccgg cttgtggaat ggggcatatc
     2221 ggaaaagttc tggaagaata cggttataag gtaaaagcta cagatatttg ttatagggga
     2281 tatggagaag aaagagaagt tgattttttt acagtaacag aaaatatatt ggatatagta
     2341 accaatccac catatttttg tgcaagtgag tttttaaggc acgctcttga aatatcagga
     2401 cctaaagtaa agatagcaat gctatttcgg ttggcttttt tggaaggtca atcaagatat
     2461 gaattattta ggaaatatcc tccaaagaga gtatatgtat tttccaaaag gcttaattgt
     2521 gcaaaaaacg gagaatttga gaaatacaaa agcagtgcta ttgcctttgc ctggtttata
     2581 tgggaggtgg gatacaaagg tattacggag ttaaggtgga ttagataaaa ggatggaata
     2641 aaacaactga aaaaacgaag gaggatagta tggataagaa tgaagtatta caatcacagg
     2701 aaaatcagac aaaggaagtt atgcaggaga ttaaagagga atataccaaa acagctgact
     2761 ttttagaaga acatataaat cagcagcttg tgattgctaa ggaaatgaaa gaagagatgc
     2821 aaaataagga ctttgatgta aatatcaaag aattgaaagc actcaaagaa gaaatcaccg
     2881 gattaaaagc tgaaattaaa cgattaaacg aaatggaaaa tataactttt ggttcattga
     2941 ttataagaga tatcaaatct gtaggaaata cccttatcaa tttacaggaa aaagcggtag
     3001 gaagtattaa acatctgtat gataatatga aacatcagct ttcctataac cttaccaaag
     3061 cacaggaaaa atttgtacag atgaaaatag gaattgtaaa aggattggta aattccatgc
     3121 aggattttat caaggatcaa caaaagaaac tggatagttg cttagcaaaa cttgataatc
     3181 tatctaaaga aattcaaaaa gatgaagaaa aactggaaaa aggcaatctg aataaagaga
     3241 aaaccctgat aaaaaaaagg gaacaaagca tagaggaaaa agaaagtcaa aaggaaaaga
     3301 tggagaaaaa accgtctgtg ctaaaaaaat taaaggaaaa tcagcaaaaa atcaagcagg
     3361 aagaaaagaa taaagatata aaggcactta aaaaagataa gggaatggaa ctataaaaaa
     3421 gaggtggtag ttatgaatga cctcataaaa aactatgaaa atattcctga tgagatgaaa
     3481 aaagagaagc gttggtgcct atataaaatc attcaaagag acgggaagaa cacgaaactt
     3541 ccactaatgc caaataaaga gccggcaaaa tcaaatgata aagctacatg gaatagctat
     3601 gaggattgta tcatggcatt aaaacataat gttggcgaag ggcttggctt tttcttagga
     3661 gatggataca ttggaataga tattgataaa gtaagtgatg acattatgga gtacaatacg
     3721 aatcatcatg taagctctat gacggctgat tttttaagag aagtttccac ctatgctgag
     3781 atttctccat cgaaaacagg actacatttt attggaaaag gagaggtgcc gggagaaaga
     3841 aaaagatata aaaatcttga aatttatgat aaggataggt tttttacagt taccggtaat
     3901 gttataaagg atagagatag gagcaaaata gaaagtattg acagtgagct aaagccctta
     3961 tatgaaaaat atatgccaaa gacaaataaa attagtgctg aaaataaaag aagtccaacg
     4021 gttacttctt acaatgggga tcaggacata ttagaaaagt tatttgacag gggatatttt
     4081 tcatatgcag gagaagattt aagacaaatt tactatggta attatgaacg ctattttaac
     4141 agccaatcgg aggctgattt ttttatgcta caaaggctgc tttactatac aggaaatgta
     4201 gaaatggcaa tatcatttat ggaaagtagc ggactgaaaa gagaaaaatg gtataaaaga
     4261 cgaggcaata ccgattatat ccactatatt gcagataagg cgataagctc tatcaatcaa
     4321 ttttatgatt gggaaaaagt atatacatca aaggaaaaaa tagaagaaaa aagatatgaa
     4381 aataagaaga aaaaggaggg agatacagtg ccaagatatg aatttgatga agtcaaacag
     4441 attcttgatt ttgcaaaaga agaatttaaa gaaaatatag acaggtatga aacttatctc
     4501 aaagtgatgg gaaataacta taaatatccg tactttaacc agcttagcat atatacggta
     4561 aatgaaaatg caactgcttg tgcagaatat gactattgga aaagtatagg aagaaatgta
     4621 aatagaggag aaaaaggaat acctgtttta gacattgaaa gagagaagat aaagtatatc
     4681 tttgatgcaa gtcagacagt aagtttaaat cacaacattt ctgaagtaaa gttatgggaa
     4741 tatagcaata ataagcatgt agctgcctta gatactctta tcgatgtttt caaagaaaaa
     4801 aacagtaacc ttatattttc tactgaag
//
LOCUS       DARYUW010000093         4820 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYUW010000093 DARYUW010000000
VERSION     DARYUW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4820
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            29..1459
                     /locus_tag="TVW11_001868"
     CDS             29..1459
                     /locus_tag="TVW11_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1365934.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            1537..3168
                     /gene="rlmD"
                     /locus_tag="TVW11_001869"
     CDS             1537..3168
                     /gene="rlmD"
                     /locus_tag="TVW11_001869"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1365935.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            3188..3469
                     /locus_tag="TVW11_001870"
     CDS             3188..3469
                     /locus_tag="TVW11_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365936.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            3556..4335
                     /locus_tag="TVW11_001871"
     CDS             3556..4335
                     /locus_tag="TVW11_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1365937.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            4332..>4820
                     /locus_tag="TVW11_001872"
     CDS             4332..>4820
                     /locus_tag="TVW11_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HEL1365938.1"
                     /translation="MIKELEKVMIEDVEYSYDPEKEYIKDGHAFCKVCHERKDRKVME
                     FFDNKMIFKISCKCDRDREARKKEREKQMEIERLKKNCFNSIIQWSYTFENYQGEENQ
                     SLIIAKNFVKDYEQMKKENIGLLFYGSVGSGKTYLACSIANSLIEQYQIGVKIRNFAQ
                     LIN"
BASE COUNT         1618 a          798 c         1050 g         1354 t
ORIGIN      
        1 gtattagaat actaagagtt ggaagagcat gacgagatac caaaagggtg gtctaagcca
       61 ccacgaagaa ttacgatatt tttatttatt aagaaattta aattatttga ctgagactga
      121 acgcagagaa tttacctttt taaagtcaaa gatggagtca agggctatgc cttctcgttc
      181 tcagcgctcc ttgactcatt atactagggg tgggcgtgac gattatgctc aagcttcaca
      241 ggataatgct gatgcttatg atatgagtga tgagcagcag gctgggccta atggcctgcc
      301 tctttatcca agatcagaaa gacgtagcaa aaggcatcag caaaagccaa tactagcccc
      361 tcagcaggac ttctatgatg acccagatca ggcgatctat gaggagcttg cgcctgaggc
      421 tatgcctaaa aagggtagaa ggaaaaaaaa gaagggacgt ctgagacgtt ttttcagaat
      481 actctttttc ttgttgctgc tgcttgttgc agggatagct ttcatgtttt tcaagggaat
      541 gatggacgtg tctactaaca aggccaatta taagccagca gtttcgcagg tctttcatgg
      601 tcaggatact agcgatggca ctaatatttt aattctaggc tcagaccaga ggattacgca
      661 aggctcaaca gatgctcgaa cagatacaat catggtggtt aatgttggca ataaggagaa
      721 taaaatcaaa atggtctcct tcatgaggga taccttggtt aatattcctg gctatagcta
      781 taataatcag gattcctatg atttaaaatt gaacgcctcc tttaatttag gagagcagga
      841 aaatcatcaa ggagcagaat ttgtgcgtca gacactcaag cataattttg atattgacat
      901 taaatattat gtcatggttg actttgaaac ctttgctgag gctattgaca cactgtttcc
      961 agatggtgtt accattgatg ccaaatttgc tactgtaaat ggcgaagcag tcgctgctgt
     1021 tgatgtacca gatgatttac gaatgaaaga cggagtggtt cccaaccaaa ccataacggt
     1081 tggtgagcaa aaaatggatg gtcgtaccct gctcaactat gctcgcttcc gaaaggacga
     1141 tgagggtgat tttggtcgga ccgtacgtca gcagcaggtg atggctgcta tcatgtctca
     1201 aatcaaggat ccaaccaagc tctttacggg ctcagcagct attggtaaga tttatgccct
     1261 aacctcaacc aatgtctcct tcccatttgt ccttaaaaat ggagtgtccg tcttgactaa
     1321 tggcaaaaac ggtgtggagc atgtgacgat tcctgaaaat ggggattgga ttgatgaata
     1381 tgacatgtat ggtggtcagg ctctctttat tgattttgct aagtatcaaa atcgattatc
     1441 taagctggga ttacgctaag atatgctata atgaagggta acgatggttg ctcttctttt
     1501 ttgagtgatt agtgtagtaa aagaaaagga aagtaaatgt taagtaaaaa cgatattgtt
     1561 caggtggaaa tttctgattt aagccatgat ggcttaggaa tcgctaagca tgaaggcttt
     1621 gttttctttg ttgaaaatgc tcttccaggt gagatcattc agatgcgtgt cctaaaggtc
     1681 aataaaaaca gtggctttgg caaggtagag acctatctaa caacctcacc gatgcgtcaa
     1741 aaaaagctgg atgtgaccta tctgcgtaca ggtattgctg atttggggca cttgctttat
     1801 ccgcagcagc tgctctttaa gcaaaagcag gttcaggata gtctctataa gattgcaggg
     1861 attagcaatg ttgaggtcaa agaaacaatt ggtatggaat atccttatgc ttatcgaaat
     1921 aaagcccagg ttcctgttcg tcgtgtcaat ggtcagctag agactggttt tttccgtaag
     1981 cattctcatg agctagtgcc gatttctgat ttttacattc aagataagga aattgatcgc
     2041 ttgattgcct ttacacgcga ccttttgcgc cgttttgaca tcaagcccta tgacgaaaag
     2101 gagcagtcag gcctgattcg tcatcttgtg gttcgtcgtg ggcattattc aggagaaatc
     2161 atgctggttt tagtgacaac acgacctaaa atctttcgta tcaaccagat gattgatagc
     2221 cttgtcgcag aatttccagc gattacttct atcctgcaaa atatcaatga caagcctact
     2281 aatgttatct ttggtaaggc gtttacaagg ctttatggaa aagagacaat cacagatacg
     2341 atcttgggca atcaatactg tatttctgct cagtccttct atcaggtcaa tacaacaatg
     2401 gctgaaaagc tctatcaaac agctattgat ttttctgaat tgaccgctga cgatgtggtg
     2461 attgatgcct attcaggcat tggaaccatc gggctatcct ttgctaaaga agtcaaagca
     2521 gtatacggtg tcgaagtgat cgaagcagca gtgcgtgatg ccgagaaaaa tgcagcgcta
     2581 aacggtatta ccaatgccta ctatgtcgct gacagcgctg aaaatgcgat ggcaaactgg
     2641 tgtcaggagg gcataaagcc aacagttatc attgtagacc ccccacgaaa gggactaact
     2701 gagagcttta tcaaggccag tgcagcgatg cagcctgaca aaataaccta tatatcctgc
     2761 aaccccgcca ccatggcgcg tgacatcaag cgctacgagg aactcggcta taaactccag
     2821 aaagtccagc cagtagactt gtttccaatg acacatcatg tcgagacggt agcattattg
     2881 tccaaactta atgtcgataa gtatataagt gttgaaatag agcttgatga acttgatttg
     2941 acaagtgcag aaagcaaggc tacctatgct aaaattaaag agtatatatt agaaaaattt
     3001 ggttttaaag tttcaacact atatatagca cagataaaaa gaaaatgtgg aatagaactt
     3061 agagagaatt acaataaatc aaaaaaagat aagcaagtta ttccgcagtg tacacctgag
     3121 aaagaaaaag ctattatgga tgcgttaagg cactttaaaa tgatttaaga gaaaggagag
     3181 gtattatatg aggtggataa taaaaataat attgtttcca ttcagcttgc tacttagtgt
     3241 ccttactgcc tttctgacat ttatacttgg cataggaaca actattctgt atttcttaat
     3301 gctgatgtgt atagttgctg caataggatc atttatgcaa aaagatatat cacttggcat
     3361 tgaggcatta gtattaggat ttttgttaag tccttatgga ataccgatgg ttggagcagc
     3421 agttatagca ttctttaaag gaatcaatga agcaataaaa tcaatctaaa aaatttcata
     3481 aaaatggtta ccaaaggcga tagagaaaaa ctatcgtctt tttctttgca aatttttaag
     3541 gagggaggtg aagcgatgga ctttgactat ttttataaca gagaagcgga aagatttaat
     3601 ttcttaaaag taccggagat attggttgat ggagaagaat ttaaaggatt atccgctgaa
     3661 gcaattatcc tttattcaat gcttcttaaa cggacaggaa tgtcctttaa gaataactgg
     3721 attgataagg aaggcagggt atttatctat ttcacagtcg aagaaattat gaaaagaaga
     3781 aatatctcaa agccgactgc cataaaaaca ttagatgaat tagatagtaa aaaaggaatt
     3841 ggactgattg aacgggtacg gcttggactt ggaaagccga atatcattta tgtcaaagat
     3901 tttatgagca tatttcaggt aaaagaagat gacttacaga agttaaaaaa ttttacttca
     3961 gaagtaaaag attttaacct cagaagtaaa gaaaatgaac ttcaagaggt taagaacctt
     4021 gactctaact atatagagaa taataagagt aagtatagta agagagaata taattttagt
     4081 gaaaacgggc ttggaacatt tcaaaatgtg tttttagctg ctgaagatat atcagactta
     4141 caaatcataa tgaactcaca gcttgataat tatattgaga gattatctgc atatattaaa
     4201 agcaccggaa agacctataa agaccataag gcaacaatcc tttcatggtt ttataaagat
     4261 cagggaaggg gcaaagaagt gaaaacatca aatatcccga catgggaaga atatgataaa
     4321 ggagaacacc tatgataaaa gaattagaaa aagtaatgat agaggatgta gagtattctt
     4381 acgatcctga aaaagaatat atcaaggacg gacacgcctt ttgtaaagtt tgtcatgaaa
     4441 gaaaagacag aaaagtgatg gagttctttg ataacaagat gatatttaag atttcttgca
     4501 aatgcgatag agatagagag gcaagaaaaa aagaaagaga aaagcagatg gaaatagaac
     4561 gattaaaaaa gaactgcttt aactctatta ttcagtggtc atacaccttt gaaaattatc
     4621 agggagaaga aaatcaaagt cttatcattg caaagaattt tgtaaaagac tatgagcaga
     4681 tgaaaaaaga aaatatcgga ctgctatttt acggctcagt aggaagtgga aaaacctatc
     4741 ttgcctgctc cattgcaaat agccttattg aacagtatca aataggcgtt aaaataagaa
     4801 attttgcaca gcttatcaat
//
LOCUS       DARYUW010000094         4762 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYUW010000094 DARYUW010000000
VERSION     DARYUW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4762
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..219
                     /locus_tag="TVW11_001873"
     CDS             <1..219
                     /locus_tag="TVW11_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphopantetheinyl transferase family
                     protein"
                     /protein_id="HEL1365939.1"
                     /translation="NIGSNIPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDNQRI
                     KIEDKVKRSNKDLIAFSISSKYFGAICI"
     gene            228..1811
                     /locus_tag="TVW11_001874"
     CDS             228..1811
                     /locus_tag="TVW11_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1365940.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            1826..>4762
                     /locus_tag="TVW11_001875"
     CDS             1826..>4762
                     /locus_tag="TVW11_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1365941.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAI"
BASE COUNT         1781 a          531 c         1012 g         1438 t
ORIGIN      
        1 aatataggca gtaatatacc aatgttttat agatattgga cagcaaaaga agcctaccta
       61 aaatatgaag gatatggtct tataagaaat ccgaaagaaa tagaagttat ttatatcgac
      121 aatcagagaa taaaaattga agataaggta aaaaggagta ataaagattt gatagcattc
      181 agcatttcat cgaaatattt tggagcaatt tgcatatagg aggaagtatg aatatagaat
      241 tgaaagaaaa tttagaaaaa aattatgatg acaatgtttg ggaacatgtg accttgggag
      301 agtttgttgc gaactgtgcg gaaacgtata aagataaaac agcgattgta gatggagaat
      361 taaacttatc ttatgatgag cttgataaac tttcgaataa gtatgctaat ggactactta
      421 aagcaggttt taaaaaagga gataagattg tattacagct tccaaattgt tatgaattta
      481 tagtgatatc ttttgcaatg tttaaaacag gaattattcc gattatgagt ttgcctgcac
      541 atcgaaagaa tgaattaaag ggtattatag aaaagtctga ggcggtagca tatatttcaa
      601 aggataaata tttaggtttt tcatatgtgg atatggttcg ggatatgaaa tctgaattaa
      661 atacgaactt ggagatttat attcttggag aaagtgaaga atataaaaat ttttcgtcac
      721 ttattgagaa tgattgtttc tataaatatc cggatgtcga ttacaggagc ataggattat
      781 tgttattatc tggcggtaca acaggaatac cgaaactgat tccaagaaga cattgcgatt
      841 atatctatgt tgcaaagaaa acgacggacc ggtgtaacgt aaatcaggaa agtgtatatc
      901 ttgcttcttt gccaatagct cataattttc ctttggggtg tccagggata atgggtactt
      961 ttgcaaaagg cggaaaggtg gttttgtgca atgtgacaag ccctgatgaa attttacctt
     1021 taattgagga agaaaaggtt acgataacag gatttgttcc tgcaattgcc aatatttgta
     1081 tggattattt agagtatgaa gagtatgatc tttcctcttt ggaggttata caagtcggag
     1141 gttcagtttt ggaaccttgg ttggcagaaa aaattgaaaa agtttttgat gttaaactac
     1201 aacagatttt cggaatcgct gaaggattga tcttgacaac aaatgaagaa gataacgata
     1261 aaataagatg gcaaacacaa ggcaaaccaa tcagtgaaca tgatgaaata ctgattgtgg
     1321 atgaacaagg aaaaattgta gggattgaag aatatggaga acttatcgtt agaggtcctt
     1381 ataccattta tggttattat aatcttcctg aagtaaatga aacatgtata acacaagatt
     1441 gttattttaa gactggtgat aaagcacgaa aactaaaaga tggtaattat caaattgtcg
     1501 gaaggatcaa agaaatcatc aatagagcag gtgaaaagat aacaccactt gaattagaag
     1561 aaattttgct tactcatgaa aatatcaact cggtacaagt tgtagggctg ccagatcgtc
     1621 tgcaaggaga atccattgct gtatttattt taaatggaga taaggagctt acactggaag
     1681 aagttagaaa attcttgatt tctaataatg tggcggattt taaattgccg gatactgtta
     1741 aatatattga tgcgtggcca ttaacagctt tagggaaaat agatagaaat aaattaaaag
     1801 aaacttttta aaggaggatt ttggaatgga acttaacaat ataaaagaaa gagctaaaga
     1861 attagtaaag gattggttga aaagtatatt tgtagagaaa gtagtttcag aaaatgaaaa
     1921 tttaattgaa aaaggtttaa gttccattca agtcatgcaa ctgtctggaa aattaaagaa
     1981 aacggggata aaaatttcgt ttgcaaaact tatggaagaa ccgaatttgt ccaagtggta
     2041 tgaacttatt gataaatcca gagtgaaaag tgataagaat atagagtcat caattatcca
     2101 aagtgatgaa agtaagtttg atttaacaga tgtccagtac tcctatttaa tcggaagaga
     2161 agatgatcag attttaggtg gcgtgggttg ccatgcatat cttgaaatag atggagaaaa
     2221 tattgatgag gataagttaa aagaggcttg gaataagctt caatacagac atcccatgct
     2281 tagaacaaaa tttacgaaag acgggaagca ggaaatatta tacaaaccgt acagtgaaga
     2341 aatagaagtt tttgatttat ctgatcttga tgaagaaacg ctgcatctaa aattagtaga
     2401 aattagagaa caaaaatctc ataggaaatt aaatgtaaat caaggtcagg ttgcaggagt
     2461 agcactagca aaattttcag atgagaagtc aaggatattt tttgacgtag atttgcttgt
     2521 atccgatgta atgagcatga gtattatgat taaagaatta gctgaacttt attcaggagt
     2581 agaacttgat aatttgaatg agtatacgtt taaggattat atgcaaaacg gaattggcga
     2641 atcaatcaat gatgcagata aggagttttg ggaacaaaaa ataaattcct ttgaaataga
     2701 aagaccgaat ttaccattaa ggaaacagcc ggaacaaatt aaagaaacga agtttacaag
     2761 aagaaagaga attattaaaa aaagtgaatg ggaaaccata aaagatatag cagcatcgta
     2821 tcgaagtaca ccatctatgg ttcttctaac tgcctatgct cttgttcttg aaagatggtg
     2881 taatcaggat aaatttttta tcaatatacc gctatttaat agagatttag aaaatgaaaa
     2941 tctaaaagaa atggttgctg attttacaaa tattttattg gtagagcatg aggctgtaga
     3001 tgattcaaat tttttagata atttaaagag aataaataag acattcttgg aaaatgtatc
     3061 tcacagtgag tataacggag tgcaggttca aagagatata tcaaaaaaac aaggtacaag
     3121 tgtgtatata gcacctgtgg tttttgcgtg taatatagat tatccattgg aaactgaatt
     3181 ttcaagaaaa aatttaggga aagtatctta tatgatttct caaacaccag gagtttggct
     3241 tgattttcaa acatatattg tagatggaga tttaattctt tgctgggata gcgtggatga
     3301 actttttcca acaggaatgt tagaagacat gatggattct ttatatgaat tgatcatatc
     3361 tttaacacag aaggaagaat gggaaaagaa agtagatgtt ttacctgaaa agcaaaagtc
     3421 tattagaatg caggatgttg agggaatttt accacttcaa tatcctagcg aaacgttata
     3481 tgacggattt ctcagaaatg taaaactcaa tccagataga gttgcgatta tagattctga
     3541 aacgaaggaa gagataacat atcataaact ttatgaaatc tctttaaaag ttgcggattg
     3601 tttaggtaaa aatggtgtta aaaagggaga ttatgtagga ataacacttc caagaggtag
     3661 cagacaactt tatgctattt ttgggatttt atttaccggt gcagcatatg tatcaattgg
     3721 tattgctcag ccaaatgata gaagaactaa aatttatgat caaatcggaa taaagtgcat
     3781 tataagtgat gaaaagacag tgatagattg taaattaaat aaaaatgaag ttaaaattat
     3841 tgatttggat gtagctatgg caaatgtggc taaattaaag caacctgttg aaattagccc
     3901 ttatgatagt gcgtatatta ttatgacgtc tggaacaaca ggtgttccta agggtgttga
     3961 gattatgcat acaagtgccg ttaatacttg cattgattta aatgaaaaat acaatgtaaa
     4021 tgctgaagat acaatactga tggtgtcggc aatagacttt gatttgtcgg tttatgatat
     4081 ttttggaata cttcatgctg gaggaacggt tattacaaca agtgaagata attatagaaa
     4141 tcctgatgaa tggttaaatt tagtcgatga atataaggtt acaatatggg attctgtgcc
     4201 gattttgttt gatatgattg ttactatggc tgaaggtaaa aatagaaact taccttttag
     4261 aattgtgatg ctttcagggg attggattgc tataaattta ccagaaagat tctataatat
     4321 tagtgaaaat ataaattcta ttgttgtcgc tatgggtgga gccacagaag catctatttg
     4381 gtcaaaccat ttgaatgtac caagaaaaat accgaaagat tggatttcca ttccatatgg
     4441 tagacctttg aaaaatcaag tgtatagagt tgtggatgaa tttggtagga tctgccctaa
     4501 ttatgttaaa ggtgaacttc ttatcggtgg agttggtgtt gctaaatgtt atcatggtga
     4561 cgaagaatta acgaataaaa agtacttcga acaagatggg atgaggtggt atagaactgg
     4621 agataatggt agaacatgga atgatgggat tattgagttt cttggaagaa aagatactca
     4681 ggtaaaagtt aaaggacata gaatagaact tggagaaata gagaatgctt taattgtatt
     4741 tgaaaatata aaaaaagcga tc
//
LOCUS       DARYUW010000095         4589 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYUW010000095 DARYUW010000000
VERSION     DARYUW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4589
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..405
                     /locus_tag="TVW11_001876"
     CDS             <1..405
                     /locus_tag="TVW11_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1365942.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TVW11_001877"
     CDS             414..1085
                     /locus_tag="TVW11_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365943.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TVW11_001878"
     CDS             1102..3375
                     /locus_tag="TVW11_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365944.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3849..>4589
                     /locus_tag="TVW11_001879"
     CDS             3849..>4589
                     /locus_tag="TVW11_001879"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1365945.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAE"
BASE COUNT         1496 a          891 c          946 g         1256 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa cgaaactacg gagagaaaga tgagctttgt cgtttctcac ttccaaccgc
     3781 catgttaaaa tcttctctga gaaagaatgt tataaaaaat aatcattcta tcaccaaagg
     3841 agagaaaaat gataactaaa aaacagagaa aactaaaaag acacacaaca atcagacgcc
     3901 tgtgtcatca agccctagca gctaccctca tcacaggaag cctgatggga acaggactac
     3961 ttggaaataa agtcgtgtat ggggatatga aaagcgatgc caaaaaggta ttagcaacat
     4021 tgcaaaaagg taatcataaa caagagttaa aaaaagttct tagaactatt ggtgatgata
     4081 gtttgctatt attatggtta cttgtatcgg gtgattccaa tttagatgaa agtaataaaa
     4141 gttttgatta tttatcaatt tggaatactg gatctagagt tggtaaagtg atatctccta
     4201 ctgaatactt taaacaagaa tcaaaaaaca ctgaaaatag gcaagctgtt tatagtgaat
     4261 ttaaacaacg cgtagaagaa cgatctaaaa aagccaagga agccactgaa gcactaaacc
     4321 aaaaagctca attggaggct acagttaaaa atataaacga agaacttgaa aaaactagag
     4381 aaggttttaa agttgtgagt gaaaactcaa acaaattaga aaaacaatta atggctgaga
     4441 aaataaaaac acgtacagct gaagaaactg ccaaacaagc taaaaccgat aaagaaaaag
     4501 cagaggctga agctaaaaaa gcgaaagagg aagctaagac tgcggaagga aaagttaaac
     4561 aagcagaaac tgagaaaagg aatgcggaa
//
LOCUS       DARYUW010000096         4420 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYUW010000096 DARYUW010000000
VERSION     DARYUW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4420
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..159
                     /locus_tag="TVW11_001880"
     CDS             <1..159
                     /locus_tag="TVW11_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365946.1"
                     /translation="WYKSKQVDLNAAEVQNLALEMAYRDVVDSNNASLVLDWSENPDV
                     IFDGNGGS"
     gene            159..1262
                     /locus_tag="TVW11_001881"
     CDS             159..1262
                     /locus_tag="TVW11_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1365947.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPPGKTGEQGPPGPAGKPGTTDYNQLQNKPNLDAFAQKKE
                     TDSKITKLASSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSGIKHSSSVG
                     GAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVM
                     RQPSAPNFSSALNITSANEGGSAMQIRGIEKALGTLKITHENPSLGADYDENAAALSI
                     DIVKKANGAGTAAQGIYINSTSGTTGKLLRIRNENKDKFYVNPDGGFWSCANSTVAGN
                     LTVNDPTSEKHAATKKYVDEKIAELKKLIQKTD"
     gene            1272..3176
                     /locus_tag="TVW11_001882"
     CDS             1272..3176
                     /locus_tag="TVW11_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1365948.1"
                     /translation="MSRDPTLTLDESKLVIGPDGRMHYTFTASQDNQKVRLASNCLGT
                     TRFNQVMIERGDKATDYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNSNL
                     WSKIKLTTNGMLREYHRDHIKTEIVESADGIAKRIADDTGQKLALINETIKGIKREYQ
                     DADRQLSASYQAGIDGLKTQLANDKIGLQAEIKLSAQGLSQKYDDELRKLYAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLRSVQQSTAKQISQEIRDRTGAV
                     SRVQQDLASYQRRLQDAEKNYSSLTQTVKGLQSTVSDPSGKIQSRFTQLQNQIDQRVT
                     RDDVMSIINLSGDSIKLAIQKAGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNT
                     TVNGTFTTKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDI
                     VFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAII
                     REYNSYINGL"
     gene            3185..3616
                     /locus_tag="TVW11_001883"
     CDS             3185..3616
                     /locus_tag="TVW11_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1365949.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKAAELNELLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIILIDNVLEQYEANKKGE"
     gene            3620..4231
                     /locus_tag="TVW11_001884"
     CDS             3620..4231
                     /locus_tag="TVW11_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1365950.1"
                     /translation="MRNWKIIGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLSS
                     TNDFEVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQTAAGLARAA
                     AERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIAPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEPFEYDKQTLKDLESEDKVTVIKYADLVKQD"
     gene            4242..>4420
                     /locus_tag="TVW11_001885"
     CDS             4242..>4420
                     /locus_tag="TVW11_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365951.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRD"
BASE COUNT         1457 a          882 c         1030 g         1051 t
ORIGIN      
        1 tggtataaat ctaagcaagt tgacttaaat gcggcagagg tccaaaattt ggctctggag
       61 atggcttata gagacgtagt tgatagcaat aatgctagtt tagttttgga ttggtcagaa
      121 aatccagatg ttatttttga tggaaatgga ggtagttaat gtcagagact atatcagcta
      181 tagttgtgca taaaagcatg acaaaaaacg agtgggagtc tagtgacatc attttgccac
      241 aaggccagct cgtctatgag tctgacacag gccatagtaa atttggcgac ggtaaaaata
      301 gatatgcaga tttgatctat caaggtgggc caccaggtcc ccaaggccca ccaggtaaaa
      361 caggggagca gggcccgcca ggccctgctg gcaagcctgg aacgacagat tataatcaac
      421 tccaaaataa accaaatcta gatgcgtttg cacaaaaaaa agaaactgat agtaaaatca
      481 ccaaattagc atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
      541 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctacggctta
      601 aacctaatag tggtattaag cactcatctt ccgtaggagg agcgattaac attgatatgt
      661 ctaaatcaac aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      721 tgatgatttt acgctctgac aaagatacgt ttgatcagtc agctcaattt gtggattaca
      781 gcggtaagac taatgctgta aatattgtaa tgcgccagcc aagcgcacct aatttttcct
      841 cggcacttaa tataaccagt gccaacgaag gcggtagtgc gatgcaaatt agaggcatcg
      901 aaaaagcatt gggaacgctc aaaattactc atgagaaccc aagtcttgga gcggattatg
      961 atgaaaacgc tgcagcgtta tctattgata ttgtcaaaaa ggcaaacggt gcaggaacag
     1021 ccgctcaggg aatctacatt aactcaacct caggcacaac agggaagttg cttagaatta
     1081 gaaacgaaaa taaagacaaa ttttatgtaa atccagatgg tggcttttgg tcatgtgcaa
     1141 attcgactgt agctggtaat ctaacagtta acgatccaac atctgaaaaa catgctgcga
     1201 ctaaaaaata cgtagacgaa aaaattgctg agttaaaaaa acttatacaa aaaacagatt
     1261 aaggaggata aatgagtaga gatccaacac taacattaga cgagtcaaaa ctcgtcatag
     1321 gaccagacgg ccgcatgcat tacacgttta cggctagtca agacaatcaa aaagtcagat
     1381 tagccagcaa ctgtctagga acaactcgct ttaatcaggt tatgattgag agaggcgaca
     1441 aagcgactga ctatgttgcg cctgttgtcg ttgagggcag cggtgagtcg acaggtgtgt
     1501 ttaaaagtct tgaggagatg cttagtggtc tacagtctat taatttagag ctgacagata
     1561 ccaaaaactc caatctttgg tcaaaaatca agctcacgac aaacggtatg ttacgcgagt
     1621 atcatcgtga tcatattaaa acagagattg ttgagagcgc agatggtatt gccaagcgga
     1681 ttgccgatga cactggccaa aagctggcac taatcaatga gaccatcaaa ggtatcaagc
     1741 gtgagtacca agacgcagat agacagctat ccgcgagcta ccaagcgggc attgatggcc
     1801 taaaaactca actggccaat gacaaaatcg gtctacaagc tgagattaag ctgtcagctc
     1861 aaggcttgtc gcaaaagtac gacgatgagc tgcgcaagct gtatgctaag attaccacca
     1921 cctcatcagg cacgaccgaa gcgtacgaaa acaagcttga gggcttgcgt gctgagttta
     1981 cccgtagcaa ccaaggcatg cgcactgagt tagagtcgca gattagcggg ttaaggtctg
     2041 tgcagcagtc aactgcaaaa caaatctcgc aggagattag agacaggaca ggtgctgtta
     2101 gtcgtgtgca acaggactta gccagctatc aaagacgctt gcaggacgcc gaaaaaaatt
     2161 acagcagttt aacccagacg gttaaaggtc tacaatcaac tgttagcgat ccgtcaggta
     2221 aaatccagtc gaggtttaca caactacaaa atcaaatcga ccaacgtgtg acaagagatg
     2281 acgttatgtc aatcatcaac ctatccggag atagtatcaa actagctatc caaaaggctg
     2341 gtgggattga tgctaaaatg tctggcagcg agattatctc agcgattaat ctcaatacgt
     2401 atggcgcagt cattgcaggt aaacacatcg ctcttgatgg caatacaacg gtcaatggca
     2461 cttttaccac taagatagcc gaggctatca aaatcaaggc tgatcagatt atcgcaggta
     2521 ctttagatgc ctcaaaggct cgtatcatta atctaaacgc tagcagcatt gtcggcttag
     2581 atgctaattt tatcagggcc aaaatcgagc atacgatcac aagtttgctc gagggcaaag
     2641 ttatcagagc tcgcaacgga gcgatgatga ttgacttgtc aaactctaag attgacttta
     2701 acagcaacgc taccattaac tttaataaca aagacaacgc tttggtacgt aaagacggta
     2761 cccacacagc ctttgtgcat tttagcaatg ccacgccaaa aaattataca ggtagtgcgc
     2821 tttacgcctc gatcgggata acatcgtcag gtgacgggat taacagcgcg tcgagcggtc
     2881 gtttttgcgg tgctaggttt tttaggtatg cgcgaggtta cgagcacaca gcgcttgtcg
     2941 atcaggccga aatttacggt gatgatattg tctttagcga cgattttaac atcgatcgtg
     3001 gctttaagat gcggcctagc ctaatgccaa aaatggtcga tctcaataag atgtatcagg
     3061 ccattttagc tcttggccgc tgctggctac acgctaataa tacagcgtgg acctttaact
     3121 cagacactac tagtgcaatc atcagagagt ataactcata tattaatgga ttataggaga
     3181 caacatggat ttaacagtac aaaacaaaga cttaaatacg ctctatagcg tactagacaa
     3241 aattaaggtt actaacatga gagttaatcg cggccgcgct aagctgcttg ccaaagtcga
     3301 ggctaagcta agagagtacg ctaaggacga ggttgatatt attgatcagt acgctgctaa
     3361 aaacgacaaa ggcaagtggt tggtcgatga caaaggcaac gctaaattag ctgatgtcac
     3421 aaaagcagct gagctaaacg agcttttaga cgagttagcc aacgagccta tcgtcatcaa
     3481 aggccatgag tactctaagc gatttatcga ctttttggag tacttggccg aggccgaaga
     3541 tgagtttaca ggggccgaaa tcatcttaat cgataatgtc ttagagcaat acgaagcaaa
     3601 caaaaaagga gagtaaatta tgcgcaattg gaaaatcatc ggcaaatatc cacaaccaaa
     3661 cgcgctaggg gttattgagg gtacacatgt catcatcaca ggtgatgacg gtgcatctat
     3721 cccgcaaacg ataaaaaaag atctgtcatc tacaaatgat tttgaggtca ttaaaatggt
     3781 cctcgacgag tttaaaaaat cagagtatgt cgaaatcgca atgggcgagg cagtccaaaa
     3841 agtggacgac ttggaaaaac tatcgcaaga aactgctaag acagcaacaa ctgcacaaac
     3901 agccgctggt ttggccaggg cagctgcaga gcgcacacaa aagatgatta acttgcagac
     3961 tatccacgtt ttgacaacca gcgataaagt cgagcctgac atctacaaag gcatgcttga
     4021 gcttattgcg ccggccaaaa aagggcaata tcaagagcat gatgtcttta cggtgctaga
     4081 cgacaagcat gaggatcttg caggcgaggg caatctcgtc tttgtgtatg tcaacgagcc
     4141 gtttgagtat gacaaacaaa cgctcaaaga cttggagtct gaggacaaag tcacagtcat
     4201 taaatatgcg gatttggtaa aacaagatta gaggtggtta gatgatagat tttgtacaaa
     4261 ttggtgcttt ttgtggcgct gctttgtcta tcttgggtgt ttggggattt atcgtcaatc
     4321 cctttaaaaa agccatggaa gctaacgagc tagccatggc ccaactcaaa gactcgatca
     4381 aggagttagc ctacgagcta aaaaatcttg atcgcgatag
//
LOCUS       DARYUW010000097         4119 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYUW010000097 DARYUW010000000
VERSION     DARYUW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4119
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(252..1922)
                     /locus_tag="TVW11_001886"
     CDS             complement(252..1922)
                     /locus_tag="TVW11_001886"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1365952.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            2120..2812
                     /locus_tag="TVW11_001887"
     CDS             2120..2812
                     /locus_tag="TVW11_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1365953.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            2805..3350
                     /gene="coaC"
                     /locus_tag="TVW11_001888"
     CDS             2805..3350
                     /gene="coaC"
                     /locus_tag="TVW11_001888"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1365954.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            3407..3979
                     /locus_tag="TVW11_001889"
     CDS             3407..3979
                     /locus_tag="TVW11_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1365955.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         1235 a          916 c          773 g         1195 t
ORIGIN      
        1 atttgtgaaa aattaatttt atcatttaat attaaaagtc agattattaa aaaatatccc
       61 taccaaagca gaattaaagc attaatgatt gtcaatatga cacctatact ggtaaaaaaa
      121 gattgtgaat aacgattaaa atagtaaaat atgagctatt gttatcagct tatccttaga
      181 cattaaaaaa gattgaagaa accccctttc tgaagctttc ttcaatcctg attctggcta
      241 taacaaataa atcaaaacaa tcctactgct gtaccgtctt cggtgacgtc catcttcata
      301 gctgcaggaa tctttggcaa gcctggcatt gtcatcacat ctccagttaa ggcgacgata
      361 aagccggcac cggtcttagg cactaattca cgaatggtaa tgtcaaactg atctggcgcg
      421 cctaggagcg atggatcgtc tgaaaagcta tactgggttt tggccatgca aacaggcaat
      481 tgatcccaac caaactgggc aaattgcttg agctgatttt tagctttagg tccgaattgc
      541 acagccctac caccataaat ttcagtcaca attgccttaa gtttctcctc taagctatcc
      601 ttgtctgcat atagacgctt ataggctgcg ctttcctctg taatagcctt gacaacagcg
      661 ttggcaagag caataccgcc atcagccccc ttggcccaca cgcttgccaa ttcaaccgga
      721 acagctattt ctgcacacaa ttcttttaag acttgaattt ctgctttagt atctgtcaca
      781 aattcgttga tagctacaac aatcggaata ttgaattttc gaatattctc aacatgacgc
      841 tttaaattag caaagccaga ccggaccgca gctgtatttt caaaggttaa atccgcctta
      901 gcaacaccgc catgcatctt caaggcacga agtgttgcga caataacaac tgcatcagga
      961 gccttaggta gattcggtgt tttgatgtta aggaattttt ctgctccaag atccgctcca
     1021 aagcctgcct ctgtaacagt ataatctgcc aaccgcaaag ctgttgatgt cgccagaaca
     1081 gaattacagc catgagcaat attggcaaag ggtccaccat gcacaaaggc tggtgtacca
     1141 tagattgttt gaacaaggtt aggcttgatg gcgtccttca aaatcaaggc taatgcccct
     1201 tctaccttta aatcacgcac atatacaggt gatttatcgt aacgataggc aatcacaata
     1261 ttagctaaac gagccttcaa gtccttaaga tcagtcgcca agcaaaggat agccatcact
     1321 tcagaggcta ctgtaatatc aaaaccgtct tctcttggga caccattgac aggactcccc
     1381 aagccaacaa tgacctgcct aagagaacgg tcattcaaat caaggacacg cttccagatg
     1441 atacgacgcg ggtcaatacc aagctcattg ccctgctgaa ggtgattatc aataagggct
     1501 gataaagcat tatgagctgt ggtaatagca tgcatgtccc cggtaaaatg aaggttaata
     1561 tcttccatcg gaagaacctg agcgtagccg ccacctgcag caccaccttt gatccccata
     1621 accggtccta aagagggctc acgcaaggcc agcatggttt ttttaccgat tttagtcaag
     1681 gcatctgcca aaccaataga catggttgat ttgccttcac ctgctggcgt tggattaata
     1741 gcagtcacta aaatgagctt accaggctta ttgtcctcta ctgatttgat tttttcaaag
     1801 gataatttgg ctttgtagtt accgtaaagc tccaaatcat cagcatcaat ccccaccttt
     1861 ttaacgattt ctgtaatcgg ctttaagggg acactttgag caatttcgat atctgatttc
     1921 atgaaaactc cttgactctt acttgatagt gttattatat cacacttcat ctcaaacgta
     1981 cattgatttg ttctatatac aaaaatgttc gtttttataa tggttctgaa aggaaaaaag
     2041 cttagtagcg tcagcattgt cagtaaaaat aattttaatt agtgatttta tttactattc
     2101 ttgctttttc tgataaaata tggctatgaa attattaatc acatcaggcg gaacgaccga
     2161 agcaatagac gccgttagag ggattaccaa tcattccact ggccagctag gaaagatagt
     2221 agctgagacc tttctagcaa agggatttga cgttactcta gtgacaacaa aaacttcagt
     2281 aaaaccagca cagcagcctc atttgaccat tcgtgaggtg accaatgttg atcagctgat
     2341 ggctatctta aaagaggagg ttcctaagca cgaccttctc attcacagca tggctgtttc
     2401 agattatagc ccagtgtaca tgacagactt tgatacagtt gcagctgctg atcatttaca
     2461 gaccttttta acagcaagca ataaggaagc caaaatctca tcggcagctg attatcaggt
     2521 gctctttctt aaaaaaacac ctaaagtcat atcctatatt aaggaatgga atcctaatat
     2581 aaggctagtc ggctttaagc tattggtcaa tgctccagct gaggagctaa tttcagtggc
     2641 acgagatagc ctgcataaaa acaaagcaga ctatatagta gccaatgacc tagcagatat
     2701 taaggccaat cagcacaagg cttttcttgt caatgacaaa acagtctgct ctgccagcac
     2761 caaagaggag cttgcacaat taatctatga aaggataata gccaatgact aagcgaataa
     2821 cacttgcggt ctcaggtagt atttctgcct ataaggcagc tgatctcacc agccaattaa
     2881 ccaaaaaagg ctatgaggtt actgtgttga tgacgcaagc agctactgcc tttatcactc
     2941 cgttgaccct acaggtctta tcgaaaaatc ctgtccatct agatgtcatg gcagagcacg
     3001 atgtcaaaat tgtcaatcat attgagctag ctaaagcaac agatctattt gtccttgctc
     3061 ctgcaagtgc caataccatt gctcatttag cctacggctt tgctgataat atggttacca
     3121 gtgtcgccct agccctgcct gaggcaacac ccaaactcat cgctcctgct atgaatacta
     3181 acatgtacct taacccaatt actcagggaa acatcaaacg cttagctgat cttggctttc
     3241 gagaaatacc acctaagaca gcactccttg cctgcggcga cagaggacct ggggccttag
     3301 cagatattga tgatatggtt acagcaatta gtcagcagct agcaagatag ctggtcaccg
     3361 attagcaatt gctgtattat aatataaaaa tttaatggag aatgcaatga atcataacaa
     3421 atcttctgaa atctctcgta ttgccatctt ttttgcagtc atgctggtta ttcacttcat
     3481 tagtagctgg tttttttata tctggcctgt cccaattaaa ccaacactcg tccatattcc
     3541 agttattgtt gcttctatca tgtatggtcc gcgcactgga gctatcttag gaggcttgat
     3601 ggggattgtc agtgtgatca caaatacctt ggttttactt ccaacaagcc atcttttctc
     3661 accatttgtc acaaatggta atctggcttc cttgatgatc gctatgctgc ctcgtatcct
     3721 gattgggatc actccttatt actgttataa gcttatcaaa aacgagcttg ggcttgtcct
     3781 agctggtctt gttggctcgc tgacaaacac catttttgtt ctctcaggaa tatttatctt
     3841 tttcccaaca gcctctggtg acaatgtcaa aacgtttcta actaccattg tatctggcaa
     3901 tgctattact gaaatgattg tttcagctat cgttaccatt actcttatcc cagctttatc
     3961 caagctcaaa aaatcataat attgctcaag ctatgaagca tgctgtctga taaggatagc
     4021 atgctttaat gatatgtgac aagcaaggaa attgatcctt atgtgaaaaa atgattggaa
     4081 gctattacag aaaataagtg atttttcctt ttcaacatg
//
LOCUS       DARYUW010000098         4046 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYUW010000098 DARYUW010000000
VERSION     DARYUW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4046
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..698)
                     /locus_tag="TVW11_001890"
     CDS             complement(<1..698)
                     /locus_tag="TVW11_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1365956.1"
                     /translation="MPNYAIILAAGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALA
                     PQKQLTVIGHQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGD
                     TPLIRGESLKALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANE
                     AEQEVKEINTGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLK
                     DFDESLGVNDRLALA"
     gene            complement(1054..2028)
                     /locus_tag="TVW11_001891"
     CDS             complement(1054..2028)
                     /locus_tag="TVW11_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1365957.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            complement(2029..2487)
                     /locus_tag="TVW11_001892"
                     /pseudo
     CDS             complement(2029..2487)
                     /locus_tag="TVW11_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            complement(2687..3385)
                     /locus_tag="TVW11_001893"
     CDS             complement(2687..3385)
                     /locus_tag="TVW11_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1365958.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(3378..3614)
                     /locus_tag="TVW11_001894"
     CDS             complement(3378..3614)
                     /locus_tag="TVW11_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1365959.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT         1124 a         1021 c          783 g         1118 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ctgctaggat aatggcgtag tttggcataa tgacttcctc cgtttgtaca
      721 tagatcatct cattatagca caaatggcct taatttgcag aaaaaacaag aatgctgcaa
      781 tagtccttag cttcagacaa actcccttac ctaccttgac tcctttttta aagcagctag
      841 ctagagctgc ctgtcatcgc taagtatcaa agatgtcgta aacaaagcaa gctgcaaatt
      901 agacccctca ctatgaaaaa agcagttagg ctccgcgatt gaaagactcc gagtcatcag
      961 gaacaagacc tgtatctgat agaacaagaa gggtcatcac ttcttaagac agctagcaaa
     1021 aaagatgact tagcttgtag ccactagcta ctcttagcta tcgctttcta gcgaagctgc
     1081 tgcctgctct aaaacagcca tgactgcctt gctgtgctcc aaggcctgct ctgccctttc
     1141 catgtcctta ttagagataa tatctgaaaa ggcaataaat tcatcgtaca tgcgatgaga
     1201 cgggtggtta aagttgacgg tccttgcttg ctcacctcga atggctagta aaagctctgg
     1261 tacagcatta ggagcaccta aaacagaaag aaagccttta ttcccctgaa tcgtagagac
     1321 aatctctgca ctgcaatcct tagccccaat acaaacagcc ttaaatcgct cataatccat
     1381 cagcaaaaca ccagaggtgt caacctgccg ctccatatta gctaggtact gaaccgtttg
     1441 gggcttgcca aataagccaa cgagcagatg gatattataa atattcaaat cacgcaaggc
     1501 ccctccaccc tttttaggat caaaggctgg tgcaatctcc ccacgcttaa aggcatcata
     1561 acgagaggaa tattgagaat aattgcactc cacaagctta atctctccta actcagtcaa
     1621 gtgatcctta ataaattggg tgtttggcaa atattggttg gtaatagctt ctaataatat
     1681 cagctgctta gctcttgcaa tgctgcttaa agcatcaagc tccttggctg tcatggtaaa
     1741 tggcttttca caaatgacat gcttaccagc ctcaagggct tgcttagcca cttcaaaatg
     1801 caaatgattt ggggtggcaa cataaaccgt atccacctct tcatttttta ggacctcggc
     1861 tagctgacag ctggcctgtt gaatgccaaa ggcgtcagca agcgcctctg cggtttcaag
     1921 actacgaggc gttgaaacaa tcgccattaa gtctatgctt ttgatctcct ttaaaacagg
     1981 caaaacctct ttgacaatca tgcctgtacc aacaagggct aatttcattt atttctcctt
     2041 tttagcagct tcagggtaaa ccctctgaaa ctcctctaac acaataaggc tatcctcggt
     2101 aaagcgtaag cctacctctt caaaataagg tctgaaaaag gcctcatgaa gcagccgcca
     2161 ttcttccaag cttttatcac cctctccttc cttataggca tgctctgctg gcacgtcctt
     2221 gaagggaaca agactaacct tagtaatctg gataatacag atcgcctgat ccctactatc
     2281 caaaatcacg tcatagctgc cctctttgga aagcggctca tgatcaggct catatcagtc
     2341 ataggcagag gctgtagctg ttttagtgcc ttctagcact aattgcgcta ataaatcagg
     2401 ctcagctcca aaggcccagg cctcagctag atcaccaaca ccaggattga tttgctggta
     2461 ttgagaccat aattcttctg cagtcatgtt atcacctcta ttgatcgaat cctctagaca
     2521 ggtaggctcc tgctgtatta agcaaaccta ctaggcacta ggcttcatgg aaaaaacttc
     2581 atcagctccc tcttagcctg tgacaagatt gcttgataca gctatcaact gtcaccctct
     2641 gtacagacaa gccagatctt gctaggcctt atgtcgatgt gctgtttcac tttaagctcc
     2701 aaccgccatc aattttaaca atttctccct gcatggcgct agcttttcca gatgccaaaa
     2761 acatggtcag ctcggctatt tcttcagccc taagccaacg accgatagga gtctcatcag
     2821 ccacccactg ggctaagcca cctggctcaa agtctgtggc tgtcattgct gtttgcactg
     2881 cgccaggggc aatgccaaaa acctgaatgc ctgccttggc ataatcaagc gctagctgtc
     2941 tggtaaaacc agccagagca tgcttgctgg aggtataggc agctccgccg ccacctgcca
     3001 tgaagctagc aatagagcac atattgatga taatacctga ttgagctgtc agcatctgtg
     3061 ccaaatagtg acgcgtgatg cggacagctg caaagaaatt gacctgaaag agagcctcaa
     3121 aatcagcctg tgtggtatca agcaagggct tataggcatc aagaacgccc gcagtatgac
     3181 acaacacatc aaccctaggc acagcctcaa aaagctcagc taaatcacct gtaatatcta
     3241 actgtaaaaa ctgaaaatct cctgataaat caggcttttt tgccttgtca accccataaa
     3301 cagtaaagcc atttctcaaa aacaggcgcg cctgtgccag tcctatgccc gatgacacac
     3361 cagtgatcag cacccgctta gtcatagacc tctacccagt cagtagcaag aacgtcgcag
     3421 ggagtcggtg cccacatgga aaagccctcg ccagctcctg acacgttaat caaaaagtaa
     3481 ggcgtcacct caagtgccac accattttgt tcaatgctat caaacagctg aacatagttt
     3541 tcagcgcctc cccagccctt acgaacgtat tttttcttgg ccttcaagcc tggcaaaatc
     3601 tcttcaaatg tcatggtttt ctccttttat aggtctacat catagcatga gctcttttaa
     3661 tgatcattat accaatttac tcagcttttg taagcttaaa gatcacgaaa gtcgcaaacg
     3721 tacaagtttg ctttgttttt agataaggat tcatcatctt aactaattat gacataatct
     3781 aagtgatatg aaatcctttg taacccacac cagcttttta taatacacta acctgagtgt
     3841 ctttaaaact gcggctgtaa ttcttgatta agctaataca gcatgtctag ccagtatatg
     3901 aaaataattg gaattatttt cgttagaatg ttagactatt ttagataaag cgtgttcaat
     3961 gacattattt tttgtataaa tcaaaatatc cccaaactac tattaggatt atttctttac
     4021 ttttagtcac ttttaataaa catctt
//
LOCUS       DARYUW010000099         3903 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYUW010000099 DARYUW010000000
VERSION     DARYUW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3903
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..3716
                     /locus_tag="TVW11_001895"
     CDS             <1..3716
                     /locus_tag="TVW11_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1365960.1"
                     /translation="NIDADVLKQGSETLKKELSSLNYQRQKLLEVMPKELEASEITVR
                     MGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYRVEGKSIDKGNDLANFTY
                     GTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKETMLARSKQEIIKEEFKN
                     WIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPEIELRPHQRDAIARGLFG
                     GNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIVEQFGREFNELYPAANI
                     LCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPISKQRQEYELQSQIDEIID
                     FIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDVVTFEELGIDKLFVDEVH
                     AFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGNKGIVFATGTPVSNSMAE
                     LYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEGNGYRSKTRFAKFYNLPE
                     LMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQILETFSERADKVRGKQVDS
                     SVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNIFSIWDKYRDEKSTQLVF
                     CDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKEKDKIFDKVRKGEIRVLL
                     GSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQGNENDDVHIFRYITENT
                     FDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAEIKALATGNPLIREKMDL
                     DVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIENLKKDIEKVEPYREEKL
                     EKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYTDKKQAGEFLINKIKGIK
                     KLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHYGEFGTDEIGNITRMDN
                     VLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKEKTLRLAEVNNLLDMGQ
                     KGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPDLTDIGLAYTTTPDEKH
                     EIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQIKTNIGFWDFNELVYV
                     DEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRDSKVQSFGDLDKKEKAS
                     VMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
BASE COUNT         1565 a          512 c          811 g         1015 t
ORIGIN      
        1 aaaatattga tgcagatgta ctgaaacagg gtagtgagac tttaaaaaaa gaactgtcca
       61 gtttaaatta ccaaagacaa aagctgctag aagtaatgcc aaaggagctt gaggcaagtg
      121 aaataaccgt tagaatggga gcaacttgga tacctgagaa agattataag agctttatgt
      181 tccatcttct aaaaacatcg gcatctaata gatggaatat tgatattaaa tataccaatt
      241 ttacagggga gtacagagtt gaaggtaaaa gtatagataa aggaaacgac cttgccaatt
      301 tcacatacgg aacaagcaga gtaagtgcat ataaactgat tgaagataca ttaaacctta
      361 gagataccaa tgtatatgat caagtcattg atgaaaacgg aaagaaaagt tctgtactaa
      421 atcaaaaaga aacgatgctt gcaagaagta aacaggaaat tatcaaagaa gagtttaaaa
      481 attggatttt cgatgatata gacagaagaa caaggcttgt aaaagaatac aatgagaaat
      541 tcaattcgat aaggcttaga gaatatgatg gaagtaattt aacttttgac ggaatgaatc
      601 ctgaaataga gcttagacct catcaaagag atgcgattgc tagaggactt ttcggtggaa
      661 acaccctact tgcacatgaa gttggagctg gaaagacttt tgagatgata ggaattgcta
      721 tggagtctaa aaggcttgga atgagtaaca agtcaatgtt tgtagttcca aaccatattg
      781 tagaacagtt tggtagagag tttaatgaac tgtatccggc agcaaatatt ctttgtgcaa
      841 cagaaaaaga ctttacacca gataaaagaa aaagattttg ctcaaggatt gcaaccggtg
      901 attatgatgc ggtaattata gggcattcgc agtttgaaaa gattccaatt tcaaagcagc
      961 gacaggagta tgaacttcaa agtcagattg atgaaattat agattttatc gaagaatata
     1021 aaaggaatag agatcagaaa ttcaccgtta agcagcttga aaaaacgaaa aaaggactgg
     1081 aggcaaaact aaagaaatta aatgatgatt atagaaaaga tgatgtcgta acctttgaag
     1141 aattggggat agacaagcta tttgtagacg aagttcatgc ttttaaaaat ttgtacgttt
     1201 ttacaaaaat gcgtaatgta gcaggaatta caaccacaga ttctcaaaaa tcaagtgata
     1261 tgctgatgaa gtgcagatat atggatgaaa ttaccggtaa taagggtatt gtatttgcga
     1321 caggaacccc tgtgagcaat tctatggcag agctttatac catgcagcgt tatctccaat
     1381 atgacgaact taaaaaaatg cacttgcaac actttgattc ttgggcatct acttttggag
     1441 aaactgttac agcaattgaa cttaatcctg aagggaacgg atatcgaagc aagacaagat
     1501 ttgcaaaatt ttataacctt ccggaactga tgaatatggt caagcagttt atggatataa
     1561 agactgctga tgtattaaat cttcccgttc caaatgctca ttatgaaacg ataaaaacca
     1621 aaccgacaga agaacaaaaa caaatccttg aaactttttc tgagagagct gataaggtta
     1681 gaggaaaaca ggtggattcc tctgtcgata atatgcttct gattactaat gacggaaaga
     1741 aaatggcact tgaccaaagg ttaattaatc cattacttcc tgatgatccg aacagtaaag
     1801 taaatacctg tgtaaataat atattcagta tttgggataa atatagggat gagaagtcca
     1861 cacaattagt tttttgtgat atgtcaacac catcaagtga atttaatatt tatgatgata
     1921 taaaggagaa gctgacaaaa atggggattc ctaaaaatga aacagagttt attcataacg
     1981 caaagaacaa caaagaaaaa gataagattt tcgataaggt acgaaagggt gaaattcgtg
     2041 tgcttctcgg ttcaacgcag aaaatgggag cagggacaaa tgctcaaaat aaattgattg
     2101 ctacccatga tctcgatgta ccctggaggc ctgcggattt ggagcagaga aaaggaagaa
     2161 ttgtaaggca aggtaatgaa aatgatgatg ttcatatctt tcgttatatt acggaaaata
     2221 cctttgatgc gtatcttttc caaacacttg aaaccaagca aacttatata tctcaaataa
     2281 tgaattcaaa gacacctgta agagtagcgg aggatattga tgaagctaca ttaaattatg
     2341 cggagattaa agcacttgca acaggaaatc cgcttattcg tgaaaaaatg gaccttgatg
     2401 ttgaggtaag taaacttaaa atgctggagt ccaattttaa atccaaccta tataaaatgg
     2461 aagataaggt tgtaaaagta tatccaaaag aaattaaaag tctaaaagaa aaaatagaaa
     2521 atttgaaaaa ggatatagaa aaagtggaac cgtataggga ggaaaaacta gaaaaatatg
     2581 atcagactac tttagaaaat atgggtgaaa atgaaaaaca agtggggata aaagcagata
     2641 aagaagcaat atcaaaattc acatctttaa ctttaaatgg gaaaaaatat accgataaaa
     2701 agcaagccgg agagttctta ataaacaaga taaaaggaat aaaaaaatta gatgattttc
     2761 gttctgagga agtaaaaatc ggagaatata gaaatttcga tttgttcgca tattatgaca
     2821 ggttctccaa tcagtataaa ttcaatctga agggagaaga aaatcattat ggggagtttg
     2881 gaacggatga aatcggaaat atcacccgaa tggataatgt acttgatagg atgcctgaga
     2941 gattggagca gacacttgga aaacttaaag ataccgagaa tcaacttgaa acggcgaagc
     3001 ttgaaataaa aaagaaattt ccacaggcag agcttttaaa agaaaagacg ttaagacttg
     3061 ctgaggtaaa taatttgctt gatatgggac aaaaaggaga tttaaaagag gagaaaaatc
     3121 cacttttgga agaagtgaag gaagaactga ttcattttct aaataaagaa tatgatgaag
     3181 cacacagtat agaagatttc gatacaatgt ttcctgactt gacagatata ggtttggcat
     3241 atacgactac accggatgaa aagcatgaga tacagacaag tcttgattta atcaattaca
     3301 agatgaacac ttatgtagac aatactttaa ttgacagttt tcagtatact tacgatccac
     3361 ttaatgcaag tgatacgaag gaacttatac aaatcaaaac gaacataggt ttttgggatt
     3421 ttaatgagct ggtatatgtg gatgaagaaa agttaaaagc atcacttgga cttgaaattg
     3481 atgacgatgg taatttctat gatccgcttt caaaggatat ggatttagat ggagtaatgg
     3541 acaggtatga tgcagacttt agagatagta aagtacaaag ttttggagat ttggataaaa
     3601 aagaaaaagc atccgtaatg gataggcttg gatacttcaa agaaaagata aagaaaggag
     3661 gcctacaaaa tgaaaatatt gatagaaaga tagagtgtaa ggaggaggtt agatagttgg
     3721 aatatcacaa aaatattaga gcaacggata gagaaatgca gaaacttttt gaaaatgagg
     3781 agtataacta ttccgtaaga tattttgaaa aaatagaaga aaacttattt aaaacgataa
     3841 ttcgcacacc ggagaatata gagtttccaa aatccaaaac cttgtctata aacacgataa
     3901 aaa
//
LOCUS       DARYUW010000100         3794 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYUW010000100 DARYUW010000000
VERSION     DARYUW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3794
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            22..1824
                     /locus_tag="TVW11_001896"
     CDS             22..1824
                     /locus_tag="TVW11_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1365961.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            1802..2401
                     /locus_tag="TVW11_001897"
     CDS             1802..2401
                     /locus_tag="TVW11_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1365962.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2509..3435
                     /locus_tag="TVW11_001898"
     CDS             2509..3435
                     /locus_tag="TVW11_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1365963.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3428..>3794
                     /locus_tag="TVW11_001899"
     CDS             3428..>3794
                     /locus_tag="TVW11_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1365964.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILG"
BASE COUNT         1172 a          706 c          749 g         1167 t
ORIGIN      
        1 attattttag aatggtaaaa aatggaggtg agaggagcaa tgggtaaccg tcaaatgaag
       61 ctgaaaaaat acttcctcag gtttttattg ttattatttg ctgcaatcta catttatttt
      121 tcctcttttg cctatcagca ttcctacctt gggataagtg ctgattatgt taatcatagc
      181 tgggttgtca gcaatatcca taatggcggg gaggctagct cctcaggact agctgttggg
      241 gataagattt tagagataga ccataaaagc agccaggaca atcctttgtt aaataagctg
      301 ttaattgttg agcaagcaac ctcaatgact gttttgcacc aaggcataca aagacagatt
      361 gtatttcaaa aaacacatgg gtctaaaaag atatttttaa tgtttagcct gttatccatt
      421 atcttatttg ccttatccta tggctattct agaaggcatg agatcagtcg gaccagtcag
      481 aggtattaca tctttacctt tttaacatcg ttattactgg tttcgattat tccatcaagc
      541 atgggaaatg ttgttgcccg cttgatttta gtgatttaca tcactttgtt tccctttttt
      601 attgatatgt tttggagagc aggtacattg caacaggaat ctgttaaatt ttcaaaattt
      661 tcaaaactga tcatcaccta ttctgctgca accctctgct tattgctata ttctaagtgg
      721 ttttcggtcc cactcgtcat taccatttat ttggttcgag gaattttcta tgttagcttt
      781 acctttttag tggctttatt tttaatcacc ttggttaaag atatcaaaaa caatgctttt
      841 ccaagactca atattgtcct gttggttatc ctgtgcttgc tgccattgtt tatcggctat
      901 gtgtttcctt tgccttacga tatccctttt atgtacacga tacccctatt gctgctgccg
      961 attttggcga tcattaataa cctaatcatt aacaggctca cgacctttcg ctttcatttg
     1021 ccagttccaa tcctctatgt gttcattgct atgctaggca ctgtgatgat catttgcttg
     1081 tatctcatat cagactttat gcctaagtgg ttaatgatta gttatagctt tttactaacc
     1141 ctgtgctcaa taccaatcgt aaaagacctg atttttttaa atatcagaac aggctaccag
     1201 ctgagcaaca agtctatttt cctagcagtt gaggctgaaa gagaggatat ttcgatctac
     1261 ctgcatgata cgatcataca agacattatt tattacaaaa aaaggctgga aaatatggac
     1321 gccgtctcaa aaaaggctgc ttcagatatt cttgatgatg taatctttga attaagagag
     1381 ctgtgctcaa atatttatcc cttgatgatt caagagctag gcttaaagaa tgctatttta
     1441 gacattatct ctaaatttca aaaaaaagaa tcggtgatta tcaacgacaa tatccaagtg
     1501 gaacagcttg attttgggca gcccattaat aattttatcc tcagatcaat acgagagctg
     1561 attaataata gcattcttca tggtaatgct aaggaaatag atatacacat ctacaatgct
     1621 gagcaatacg ttgtgatcaa gattgttgat ggcggacatt ttaagactgc tcgtcagaca
     1681 gaagcgcctc actttggctt aactgttatc gctgaaaagt tagcattgct gggtggtcaa
     1741 ttgcttgttg acaaacaccc tacgactatt gtcatgctca ttcctagaaa gcaggtgaat
     1801 tatgataaaa atagcaatca ttgacgacca cgaattggtc ttacaaggcc tatatgatcg
     1861 gttaaaaaag gaaacacatt ttgaggttgt cggcgctttt accagctacc aagatttgtt
     1921 attttgcttg aaatataagt ctgttgacgt tttgattatt gatctcatgc taaaggatat
     1981 tcatggcttt gacttaattg cacaaatcca gcagaaatgt cagaccgtgc caaaaatgat
     2041 tttaatttca ggattttatg agcccttgct gcacaaaaga gccttggatc taggcataaa
     2101 ggcctttctt ccaaaggaat gctcctacga cgaattaatt agcactgtct acaatgttgc
     2161 aaagggaaat caagtgattc cagatgactt gctgcagagg gaagaaagtc atctgctaac
     2221 cgagtcagaa attgagatat tgaaattaat ctcagatgaa tactcgaacg aaaaaatctc
     2281 caaaaagctc tatatcagca gaaggactgt tgatacccat gtttcaaata tatgtgctaa
     2341 gctcaatgta acaagccgag ttggagcggt gcgggaggct atcaggctga agctgatcta
     2401 acaagtcaac caaaaaaggc agacagatat tcgtaaatta cggatgtctg ttttttgata
     2461 gtgttttatc ataagccttg gttataaata agaaaaggag agaaactaat ggttgatgtc
     2521 gatacattac ttggtgacca caaaacaagg tattttggtg atggtcacaa aagaacaagc
     2581 tacagtataa atcatgacca aaataaccaa gcttacggaa caattaccca atcgggtgtg
     2641 tggtcaaata aatctgataa ggtgattcag ccacacctaa gcaccttaga tggcattgtt
     2701 ctagccagtc tagcagctga aagatatcta aaagagcaat atgaagcatg tgaagatttt
     2761 tatttatctc agttttcggt caaatcaggc aggaagccta ttgaagattt aaacagggtt
     2821 ccaattgttg tccaaaaaag ctctttcaat ggggataagg caagcttttc ggtgtcagtg
     2881 ctggatatga ctgttaatct agtatttaaa cgcattgaca cctatacagc aaaagacaac
     2941 aaaccagctg cagaggcaaa ggattacttg tcaaatcatc taaaggacat tcaccatcat
     3001 atctacgatg ttaacttttt agacgcatta gatatagcag ataagtgctc tattttttgt
     3061 aaggctaata aggcaatccg ccacgtcagc aattataagg gcatatcctc tcagctatca
     3121 agcagctatt ccttattaga gctcttgatt attttctcac agatggctga aatgttggca
     3181 tattatgctg atgatattga tagaagatac agtgaaacct tgtggatgaa aaatgtatca
     3241 gccgagctcg ttgaaccgat acctgatggt gagctggccc ttttaggtaa aattaccaaa
     3301 aacaaattac ttgatatgaa gggcaaggac tggaagctgt ttgaaatgtc aggtactgac
     3361 acacaaaatc gagtgagaat ttcaagtaaa atagcccatc aattacctag ttcggagatg
     3421 cttaacaatg cttaataaag aaattagact tgtcatatca ggcacctatt ctactggtaa
     3481 gacaacaaca gcaacggctc tgtctattgc gacaggcata cctttgatta atgcactttc
     3541 agccagagag atcctgaccg acctgtatcc aggcagacgc tttcaggaca tgaatgccac
     3601 tgagctaatg gctctaggat taaaaagatt tgaggagcgg gtgcgcgagg aagccatttt
     3661 atacctccag cataccaact ttatctcaga tggctccgtg ctaaatgaat ggatctatgg
     3721 aacagtacga atgaaggtag gcttaaatcc gggctctggc ttcattcatc gagctgcaaa
     3781 ggccatcctt ggac
//
LOCUS       DARYUW010000101         3511 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYUW010000101 DARYUW010000000
VERSION     DARYUW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3511
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..1603
                     /locus_tag="TVW11_001900"
     CDS             <1..1603
                     /locus_tag="TVW11_001900"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEL1365965.1"
                     /translation="YLTQENTEKIDNIRQIIEDWNNNQLLTEYEYFYLLNALIEAIPY
                     VSNITGTYGAFLKHWDNRALHSLTLAEETIFDNYRPNKAFNENANELVKKIKADIVYI
                     DTPYNARQYASNYHLLENIARHQKPILKGITKIFDWKTLKSDYSTKTKALKAMEDLIA
                     NINASHIILSYNTEGIISEEDLTLLLQRYSFNNQIDVKRIPYRKYQSKKKSQNKDLYE
                     LLFYIQRKPINNRFKSQTKKKAAIISQKKYIKSPLNYIGGKYRLLNQIIPIFPRHINT
                     FVDMFSGGANVGINVPAKKHIFNDMNYRINDMFRYFQSHDPLEILEQIEHRISEYQLS
                     KTNEQGFLTFRKHYNTHPNPLDLYVLSSYSYNYQFRFNNSMEFNNPFGRNRSHFSENM
                     KSNLLNFVARLHRLDATFSDQFFSDFDISTLSIDDFVYLDPPYLITTGSYNDGNRGFT
                     NWGEKQEIEMYQLIRDLNKKQIKVALSNVLVHKGKHNDLLEQFVQDESLYLTTLNYNY
                     KNASYNTRKEDSIEVLITNYKPNPK"
     gene            complement(1624..3237)
                     /locus_tag="TVW11_001901"
                     /pseudo
     CDS             complement(1624..3237)
                     /locus_tag="TVW11_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1226 a          682 c          475 g         1128 t
ORIGIN      
        1 gtatctaaca caagaaaata ctgaaaaaat tgataatatc agacagatca tagaagattg
       61 gaacaacaat caattactca cagagtacga atatttttac cttttaaatg ctttgataga
      121 agctattcct tatgttagta atattactgg aacctatggc gcttttctca agcattggga
      181 caaccgagcg ttgcattcct taacattagc agaagaaact atttttgata attatcgtcc
      241 taacaaagcg tttaatgaaa atgctaatga attagtcaaa aaaataaaag cagatattgt
      301 ttacattgat accccctaca atgctcgaca atacgcatca aattatcatt tactcgaaaa
      361 catcgcccga catcaaaagc caattttaaa agggattact aaaatttttg attggaaaac
      421 tcttaaaagt gattattcaa caaaaacaaa ggctttaaaa gcaatggaag atttaattgc
      481 taatattaat gctagtcata tcattctaag ttacaatacc gagggtatta tatccgaaga
      541 agatttaaca cttttacttc aacgatattc gttcaataat caaattgatg tgaaacggat
      601 tccttaccga aaatatcaat ctaagaaaaa atctcagaac aaagacttat acgaacttct
      661 tttttatatt caaagaaagc cgataaataa tcgcttcaaa tcacaaacta aaaaaaaggc
      721 agccatcatc agtcaaaaaa agtatataaa aagcccatta aattatatcg gtggaaaata
      781 tcgactgcta aatcaaatca ttccaatttt tccccgacat atcaatacat ttgttgatat
      841 gtttagtggg ggggcaaacg ttggtatcaa tgttcctgct aaaaaacaca tctttaatga
      901 tatgaactat cgcattaatg acatgtttcg atattttcaa tcacatgacc cacttgagat
      961 acttgaacaa attgagcatc gaatttcaga atatcaactc agcaagacca atgaacaagg
     1021 ctttttaaca ttccgaaaac attataatac tcatccaaat ccactagact tatacgtact
     1081 atcgtcttat agctataact atcaatttcg ctttaataac tcaatggaat tcaataaccc
     1141 attcggcaga aatagaagtc attttagtga aaatatgaaa tccaatctac tcaattttgt
     1201 agctcgacta caccgtttag atgccacttt ctctgatcaa tttttctcag attttgatat
     1261 ttctacatta tcaatagatg attttgttta tcttgatccc ccctacctca taacgactgg
     1321 cagctataat gatggaaatc gtggcttcac aaactggggc gaaaaacaag aaattgaaat
     1381 gtatcaatta ataagagacc ttaacaagaa acaaattaag gttgcactta gtaatgttct
     1441 tgttcataaa ggaaagcaca atgatttact tgagcaattt gttcaagatg aaagtctata
     1501 tctcaccact ttaaattaca attataaaaa tgcttcatac aacacaagaa aagaagatag
     1561 cattgaagta ttgattacca attataaacc aaatccaaaa taataaaagc atagttgaat
     1621 tagctatgct tttacaaatt caatttcttt attttgaaaa taagatggta aatcggaaat
     1681 atgcagttgt cctttaagaa ccaaatctgc tcccaaaagc aattgctcta cattgagggc
     1741 tgctccctta atttgtgttt cattagaggt ataatcaagc tgctcttgaa attttccaat
     1801 gaatttactt gacacccaca taaaataaaa ctcttcttgt ggaatcgtat ctggaaaagc
     1861 ttcccaccac tttatcggat tacgattttc atctcgtcgc ttattatcct caatataccg
     1921 aatcatttca tcagcctgat tgatagattt agaataacct tttccataag cctttgtatc
     1981 tacaatcaca ccaaaacgat cttgatagag taaaccatct ggctttctgc caccacctaa
     2041 aagcttagaa tgcaatctat atacatttct aaataattcc attgtaacaa tttcaaaatc
     2101 tcgatttcgc ttaccatcgt aagcaatatc aagcaattca atatatttca ttggtaaatt
     2161 agtctctttt aaaaattttg ccttacgctt ttctgcctgc tcatccttta attcttgtgt
     2221 aatttctagt tcaggaatag aaaaatcgtt gatcttatcc ttcaaagaaa ctctattgct
     2281 agaaatatct atcctcaaac caaaataatt caatccttga atatctgata agataatctc
     2341 cagttcatcg taaaaaccct tagcccttag tttatctaat agaatagcca aagaattagt
     2401 ttcttggaga aacttgacga tataagctct ccgagtacga acatactcgc gattattgcc
     2461 atgagttgca aaaaattccc acatcacaaa tttttcaagc ttgctatgct tagaatcccc
     2521 ctgagcttgt cgtaaagcat gaagaccacg accattaatt ttataacctt gaaatccatc
     2581 tttttcacca ttagtaaagg tacgcttaat cgtttgtgaa tcaaccaaac caacattttt
     2641 tagccaatta caaataccgc gtgcatattt atcacttgtt ccttctatat cagctttaat
     2701 aagttttttc tctgatttag tggcagatcc taaccaatca aacataatat cttcattata
     2761 ggaagtaaag cctttttcac cacgaaaacc aagctgctca cctaaataat atttagtaca
     2821 ataagtaccg ctatcagcca ataaagataa gatttgtgta gctggcgggt atgacaacag
     2881 tgcctttctt aaaatagcag tttcttcttc cgaattaatt attgccctag aaaaatgcaa
     2941 ccccttcgaa gtaattgaaa acatatccgt ttctctatct accgacacaa aattcaggct
     3001 aacagcccat cttaaaaaac catctgatgt ccaattatcc gtccaagttt tacctgtatt
     3061 ttttgcctgt tgaggtacga tgctgatttg aatcaaagaa tctgccattg catctgaacg
     3121 ctttcgggga gatttgttat tcttatcctt tgatgttcca actaattcta aatatgaaaa
     3181 tgattgaatc ccattaatca gtttgtttct gagtgattct cgtggtactt caaagaaatc
     3241 tgtacccaac cataagttct tattttcata agagctcctt aatcttatac ttattatctt
     3301 tattatagca tataattaat ccttccagtt agcattatca caaagcaaca acatttctta
     3361 tttaatgggg ctactatgta gctattttaa tacatgtttt tacctcacga aaacaccccc
     3421 acttgtcaag tctgtaactg tactgacccc caaaagttgg acacgacata ttagtgaaag
     3481 gatttagttc tgtattgcac agggctaagt c
//
LOCUS       DARYUW010000102         3505 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYUW010000102 DARYUW010000000
VERSION     DARYUW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3505
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..374
                     /locus_tag="TVW11_001902"
     CDS             <1..374
                     /locus_tag="TVW11_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365966.1"
                     /translation="LDQIFNTSKNIKITREIKEYIQEGNIIAAEQLLSEKLDPTLFSL
                     GSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTKKLERAKELYARALH
                     DLPDCKLEFNQFVEYYLIGRN"
     gene            810..1229
                     /locus_tag="TVW11_001903"
     CDS             810..1229
                     /locus_tag="TVW11_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1365967.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1230..1553
                     /locus_tag="TVW11_001904"
     CDS             1230..1553
                     /locus_tag="TVW11_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365968.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            1812..2441
                     /locus_tag="TVW11_001905"
     CDS             1812..2441
                     /locus_tag="TVW11_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365969.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2423..2845
                     /locus_tag="TVW11_001906"
     CDS             2423..2845
                     /locus_tag="TVW11_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365970.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            2987..>3505
                     /locus_tag="TVW11_001907"
     CDS             2987..>3505
                     /locus_tag="TVW11_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365971.1"
                     /translation="MNEPIAAKVTKSAKITLSEKVLDTKVRFDESRIVAYAESMSKNY
                     TEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAHQNKLTYFDAGSDGWNAMSR
                     VDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADVSGIGKSYAKEIQILAENGY
                     NIEKFERFWRAYK"
BASE COUNT         1215 a          553 c          804 g          933 t
ORIGIN      
        1 ttttggacca gatctttaat actagtaaaa atatcaagat tacaagagaa atcaaagagt
       61 atatacagga aggaaatatt atagcagctg agcagttgct ctcagaaaaa ttggatccta
      121 ctcttttttc attagggtct gtggaaaaag ataaattaac ccttgtaaaa gaaaataatg
      181 cctatagttt aatatttaat gatgtgcaaa ttctaactga tttaagttca ttacgtgctt
      241 acattgtttt atttaattac actaaaaaac ttgagagagc aaaagaatta tatgctagag
      301 cactacatga cttgcctgat tgtaagttag aatttaatca gtttgtagaa tattatttga
      361 taggaaggaa ttaataaaag aactattgaa ataccatatg gcattttgag ttcagatgcc
      421 cagtcatggc aggaggcagc gaacaagatg ctcagcgagc tacattagta ggcaatatcc
      481 taggaggatt cgccgcctca agcgtcgcca gacggttcag cttgaatgag ccaatagcag
      541 ctagggtgac gaaaccgacc tacagccgcc ggcagctttt gaagaacctt gagaacagca
      601 ggctggcaag agaaagctcg aggtttgatg attatcttcg aagagaatac cggttaaagg
      661 gaaggtattt tgcagaaaga accactattt caaatggaaa gataggttat ctttcatctg
      721 actattttga aggcaagcaa attccggttc gctctagagc ttttgttgac gaagcaggcc
      781 atattaaatg gccaaatgcc gatggcttta tggtggataa tttaggtaat cctataacgg
      841 agcaggtcac tctcaaagca ggtcaaatca ttgatcgata tggatcaagt agtggtcgat
      901 ttaccagtcc gatagaaaat ggggtgacat taccatttaa taaacgtgga ttaccctacc
      961 cagaaggata tcaagactat tataagtacg aattagtaat ggatttgacg aagaaaaata
     1021 ttgttaatgc gtattatcaa tctgaagaga ttataagaaa acaaatatct gtagaaatga
     1081 aaaaatggaa tctttccttt gatgatttag ctaatattca gaagggtgag attaccaaag
     1141 tatttgggca aggtggagga attcagatta aatttccgac aggtgttggt atttacaaga
     1201 aaatgggttt attaaaggag attaactaga tggataatac aaatatattg aattggaaaa
     1261 aagatattga agaagcaatt aaaaatcgag gttttgagag tttacattat gttttatttg
     1321 atgaagaaaa gcgacttcct tgggcatttc atctttatca aaaaaatgga aaattctatg
     1381 ttgaaggaag agatgagcga tcatatatca ttggtcatag cagggaatat cgtaaatttg
     1441 atgatgccaa gcatgaattg cttaaaaaat tagaattagt tatagaatct aatcggttaa
     1501 aaaagcagtt aggtgaacct acagaatatc cctcaccact atggaatgaa tgagtttcat
     1561 gtattgtatg ccatggcacc aagcttttag gaggcagcga gcaagacgcc caaagagcaa
     1621 cattagttgg gaatatccta ggaggacttg ccgcctcaag cgccgctaga aggttcagct
     1681 tgaatgagcc aatagcaact agggtgacga aaccgaccca caaccgccag cagcttttga
     1741 agaaccttga gaacagcaga ctggcaagag aaagctcaag gtttaagaat tatgtagcaa
     1801 gagaaaaatt catgacaacc cttgcaggca tgagtcctga ggatagtcag cgctatattc
     1861 aatggcacaa atacgcaaag gctggactta gtccgtcaga tcgagtaagg attctagaaa
     1921 tatctgagaa ggcaccgaag atagagtatc ttccgggaaa aacatcagat agtatattgg
     1981 caatatccaa gggtgatcgt ccaaatgtgg agaaagtcta cagtccagat tatattggat
     2041 ttcatagaaa acaatttgat aacggtgcaa ctagatttca gaaatttaag cccaatgtag
     2101 attaccaaga cggtttagtt ggtgacgatt taggcaatag tttttggtta agtaccaagg
     2161 acgcggatat tatccaggag ataggaaagg gaaataaccg tctttatgag acactcttag
     2221 gctttgatga agggtattta gaagatggtc ccctctatcg cttagatgtt tcaccagaag
     2281 ttgtttcaca aaaaggtgtt tcaataccaa gtggtaatga aaaaggggca aatagctggt
     2341 ggcgtcctgg aggtcgtact tatccgggga atataccaga gggagttatg caaggtatca
     2401 gtacaaagaa aggagatcac acatggcacg cagtcaatta gagtgggaag atgttagtca
     2461 atatgaggag gtaaagggct atggtcaaag ggtgtggaag catcaaggga aatattactt
     2521 tgttgccgaa gaaggtggca ttgctgttca acgagtagta tatgagttac cgtatgactt
     2581 atttgaattg ttggaaagtg gagaacgtag tcttggagat gttcattcaa agctacaaga
     2641 tggtaattgg ccaccaacag aagaggaaaa gaagcaaagt catagaaaat ttgttattga
     2701 cacaccaact gcgctgattg cagaccctac tagtgtgtct ctgttctcag aagaagaatt
     2761 atcaaaatta gtgccaatcg ctgaacaaca gtggatagat tggaagggaa agctgccaga
     2821 tgattatgtc agtcctttga aataatgttt aagatagcgg agccgagatt agctctgcta
     2881 ttttaaagca tgttcttaat aattagcctg cgacagctta tcagggagta gctcgtcacc
     2941 ttgaagccaa tgccaagcgt ctccaagcgc cgccagaagg ttcagcttga atgagccgat
     3001 agcagctaaa gtgacgaaat cagcgaaaat aaccctttct gaaaaggtac tagacacaaa
     3061 ggttcggttt gatgagtctc gcattgtggc ttacgcagaa agtatgagta agaactatac
     3121 agaagctgac gtggccaaat taaccgagct gaccacccac aatgcaaaaa ccaaaacagc
     3181 tttgctggga tattacgaag caaacagcgt tacttcgtat gaacaaattg cacatcaaaa
     3241 taagttaact tactttgatg ccggaagtga tggttggaat gcgatgtcga gagtggattc
     3301 taagctagct caaagggtta atcgtgaatt tttgataaaa caaattgaga aaagaaaaac
     3361 atttatatta acgtctaatc catatactgc tcaatcaatc gcagatgtta gtggtatcgg
     3421 gaagtcttat gctaaagaaa ttcagatttt agcagaaaat ggatataata ttgaaaaatt
     3481 tgaaaggttt tggagggcat ataaa
//
LOCUS       DARYUW010000103         3255 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYUW010000103 DARYUW010000000
VERSION     DARYUW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..1555)
                     /locus_tag="TVW11_001908"
     CDS             complement(<1..1555)
                     /locus_tag="TVW11_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365972.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLR"
     gene            complement(1558..2310)
                     /locus_tag="TVW11_001909"
     CDS             complement(1558..2310)
                     /locus_tag="TVW11_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1365973.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2641..3120
                     /locus_tag="TVW11_001910"
     CDS             2641..3120
                     /locus_tag="TVW11_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1365974.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          609 g         1005 t
ORIGIN      
        1 atcggaggta ttccttttta gtttcgatat gacctataac agtatcacca tcactaatga
       61 ttcccttatc atcactaata ctcctaagat cagccttagt taaatcagca taggccgaaa
      121 tgctggccct tccgccagta tgattaatgc tttgaatgct atcttgaatg tcctttagtg
      181 tttccatatc tttgaccaca agaactgcac cattataagt gttagctgcc tctgggaagg
      241 ttactgatgt taaatttttg acattggtat atgatttgcc caaaatatcc agctgtcgta
      301 attgactatc ccctctttgc ttaaagaagg cagtctgatt gtcctttaat tcaggcaatt
      361 gattgcccaa ggcgcggaaa tcatcttgag tgactaagta gacatagcct gtagtgactg
      421 gactaggatt tagcaaggat tctttggtta ctacaatggt ttctttttgg gatacttcaa
      481 aagaaaccat gctactataa tagactagaa aatccgaggc aggcttattg gtcttttcaa
      541 caataagtct gttaaaaacc tctttttgat tgtcaatctc tgaattatca aaattaatat
      601 gagtattttt aggaaaaagc tggttagaca ttgcctcgct attagcataa agcgcagttg
      661 ttgttgctat tgcaacaaag gccataacag ctaagagggt aatatttgcc aagcctacag
      721 cattttgctt cattctaaaa atcatctgag aggtgctgac aaaatgctct ggctggtaaa
      781 aataagcctt gttttgacga cgacgcttta agtgccaagt cataaaggaa atgtaaaaga
      841 gataggtccc gataataacg ataataactg ctataaaaaa ccgatataaa gtgtctaatg
      901 ctgtcagctt tgtcgatgat aaggagatgt aatagccaat actaagcaat atgatggata
      961 aggctgctag taataaatta ccctttggct ctttttcacc ctgttcttta tgacgaaaga
     1021 gcattaaggg agaggtcttt ctgattttaa tcaagccaac aacctctaat aaaccaaaga
     1081 tagcagcaaa gattaaagtg gtgtaaataa aagcaacggg attgatttgt aattctaaat
     1141 ggactgctcc gaccagatta gcgaaaatca aataaaagac gtgtgaaaaa atagctgata
     1201 ggatacttcc tacgactact gtccctaagt acataaaaac aagctcgatc gttgagacta
     1261 aaccaacctg ctttttattc attcccaaaa tattgtacag accaaattct cgacttcttt
     1321 gctttagtaa aaaattatag ctataaatct ccataatagt ggcaaagatg attaaaacaa
     1381 agattgctag tcctaatagc ataaacccat gtctcatcga ttctgatacg gggctcatca
     1441 tgataatcaa gacaatacaa ttgagcatat ataaaacagt gcttgccagt aaaaaaggag
     1501 ctgtgacgga taaggacttt cgtagattat tccaagctag tttgagataa aacatcttta
     1561 ttcacctcct aaaagaccgg ccatggcaat cgagatgtct ttgctaaatt ctaaattcgt
     1621 tttatttcca cgatagattt ggtggaaaat acggccgtcc ttgataaaca gtactcgctt
     1681 agcatggcta gcagcattgg cagagtgtgt taccatcaag agtgtctgac cgtctaggtt
     1741 aatggcctca aaaagattga gaatatcctc tgaattgcgg taatcaagtg ctgctgttgg
     1801 ttcgtcagct aataataatt gcggattggt gattaagctt cttgcaatag caaccctttg
     1861 cttttgacca ccagaaattt caaatggacg tttatctaaa agcgtttcaa tgcgcagctt
     1921 aggggcaatg atgttgagcc gtctttccat ttctttaaat ggcttacggt ttaaaacaag
     1981 gggtaaaaag atattatctc tgatcgatag ggtgtctagg aggttaaaat cctgaaaaac
     2041 aaagcctagg ttttgaagtc ggaaattagc taggtcaccc tccttaattt ttgtaatgtc
     2101 agtgccattc aataaaacag atcccttggt tggtttttcc agagttgcca gaatatttaa
     2161 tagggttgtt ttccctgagc ctgactctcc catgatggca ataaactcac ccttgtcaac
     2221 cttaaaatca acatcttgta aggctctagt ttcttccttt gaaaagcgtg tccgaaaaac
     2281 cttctctaaa tgattaattt ctaataacat atgaaactcc tttgtgtcta ttatactctt
     2341 ttagctttaa atatagccac tatcgtgacg tatttagcta gtgatgcatt tagtgccttt
     2401 tgtcagcctt aaccactcct tctttcatga agcagcccag ctctcaacaa gaatcgtctt
     2461 agctgactga acctattgct ctaaactctt ttttctttac agcttatagt ttaccctaat
     2521 taatagtctg gttagcttac aagatttgat gggtgactta cagatttgta agttttataa
     2581 catcattttt cttatcattt tgatataatg aaaggagaat tctatttagg agaagcgtca
     2641 atggctaaga aaatcaaaaa aacgctaggg actgtcggaa agctgttttc cattatccct
     2701 gataccactg aaattatagg aaaaacgata gataacaccc gtcccattat cgaaaagcat
     2761 atggaacaaa agcatgaaaa ggaaatgcag ctaacgcttt tagatgatgt gattaattta
     2821 cctgttgata aagcgcaaaa gcatctggaa cagctaggtt ttgttgtcgc actattgccg
     2881 gtcaagccta gtaaaaaatg gatacatgct agcttaaatg aggttgtttc catgtcacct
     2941 aagcctggaa agcataagct gggaagctta gtaaagcttt attatgttac tgtagatgtc
     3001 cttgagaaaa gtcaggctat tttagatcaa gagaccctaa aggctgtcga acgaaatcaa
     3061 aaaatcgctg ataccatcga agctgttaag caaatcaagc ttccttttaa aaagagataa
     3121 ggctatactg taaaaaataa gctgataccg ttaggatcag tttatttttt atgttgtgac
     3181 tttaagtcta tctcgcttag caggtgccaa acaaataaac cacccgttat gtaccgacct
     3241 tcaatggtta aagtt
//
LOCUS       DARYUW010000104         3205 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYUW010000104 DARYUW010000000
VERSION     DARYUW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3205
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            196..915
                     /locus_tag="TVW11_001911"
     CDS             196..915
                     /locus_tag="TVW11_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1365975.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(1027..>3205)
                     /locus_tag="TVW11_001912"
     CDS             complement(1027..>3205)
                     /locus_tag="TVW11_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1365976.1"
                     /translation="FKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGNAYQ
                     VFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSDFIT
                     VSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKRASF
                     AVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQKER
                     NGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDDDKD
                     YEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGEN
                     TQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKNSFQ
                     YGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDDETI
                     NGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGKDPE
                     TWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQLGQD
                     LLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRAAVA
                     QQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIYSKN
                     GNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
BASE COUNT          953 a          580 c          704 g          968 t
ORIGIN      
        1 aaggtgattt attgttatga tatgcttaaa gctgctgaga tttggtcaat atctattgat
       61 atgagtgtat ttgaaatttt tagatagtgc ttacaaaaat cacatttacc tataataatc
      121 ataagattga tatgatagga gatgcctttt tagttattgg ttttattcta caaaacatta
      181 aggagaatag ttataatgcc acgtttttct aaagcgtttc aatacatggg agctacaacg
      241 atgttaggtc tatctttgct agcagctaat gtcaatgcca acactaatgc tgatacggta
      301 acggtagatt tgacctatac agcctattct aatctgacaa atgaacaaaa agcaggcatt
      361 caaaaaggca ctccaaatga agtacctatc caagataaat tgcattacgt tcttgtttac
      421 gacaaaagct gtggagtgac agcatctcca aaaggaatga tgtctacccc taaggctaac
      481 gctaaggtct tgcctaaaac gggtggtgca gcagatggtc tggttggttt ggcagtaggg
      541 ctaggcttac taagtgtttc aggctatctt atttacaaaa ataggaaaag cggtagctat
      601 gtgttgattg ccttgttggt agctggtggt gcgacaacag ctgttagtgc agttgatgtg
      661 gtacgtcatc tcaatgatat cgtcactaag actacggtta agggggtaag ctttacttac
      721 actccagaag aaaaggttga tgattactgt tatgtgggtt atattgtgac gcaagaaaat
      781 agcccagcac cgacacccga acctaagcca gatcctgtgc caacaccaga accgaagcct
      841 gagcctaagc tagatcctgt gccaacacct gaaccgacac cagatccaga atactttgag
      901 gccattcctc aataaaagtg tcagaactaa aaagccctca ttaagttgta acgctcaatg
      961 aaggctttta gcttgctttt agtcttctac gagagcgatc ctagtgaggc ttgctttaga
     1021 catccactac tgactttgtt ccttaacgga ttcttcttta gggtcagaag acgaagtaga
     1081 ttcaggtttt tcggcttctt taggatttaa ctccagataa gaaggtgctt taaagagctt
     1141 ttgagttgat ttgttgccat ttttactata aatgctggtt gaatgtgatc ctaatttctc
     1201 tgatatctct ttgagttgtt ttagctgctt ggtataaatg aaggttgttg ggtcaacagg
     1261 tttcagacca ttatcggtat caaagcgtag taggtctcct gtttggatag cgtcactagc
     1321 tgctagctgc tgagcaacgg ctgctcgtat ttctttgacc ttagccattg tcatctcatc
     1381 agggtttgta atttccaagc ctgtttgagt gttgtaaagg cgaccgctat agctagtgta
     1441 gtctggcgtg atataagttc cagaggttct ttgtgctacc atttgactat tttgtggcga
     1501 caagagatcc tgtcctagtt gaaccatctt gctggtatca atgcccaaga tatgcagtaa
     1561 ggttggtaag gaatcaattt ctccgccaaa ggtttctttg atcccgccat tggtatagcc
     1621 tggaatatgg atcatatatg gtacacgctg gagcattgca ttgtcatatt cggaccaagt
     1681 ttcagggtct ttacctagta attctgccaa gctgacattt ctggaattag aaataccata
     1741 gtggtcacca tatagaacaa agatagaatt gtcataaagt cctgtcgcct tgagataatc
     1801 aaaaaatgat ttcaaggctg aatccagata gttagctgta gcaaagtaac cattgatggt
     1861 ttcatcatcg gttttggcta gtggaaagcc ctcttcactg ctttcgcctc taaggctggt
     1921 gtaagggtag tggttgctga cggtaataaa cttagtgtag aagggttgtt gaagctgttc
     1981 aaggtacttg atagaatctc taaacatgta tttgtcattt aggccatact ggaaagagtt
     2041 tttatcagtc tgttttgaaa aatagcttga atcaaaaaag taatgatagc cccattgctt
     2101 ataagcatta ttgcgattcc agaaggttcc tacattccca tgaaagacgg cactagtata
     2161 gccgccattt tgtgctagga ttgatggtgt ggcgaattgt gtgttttcgc cgccataatt
     2221 taccataaaa gaaccactgt ttaagccaaa taatgaattt tccatcatgg tctctgcatc
     2281 agacgttttt ccagccttga cctgatggaa aaagttagag aaggctagtg tggcattgga
     2341 gtggtagagg gaattaataa aaggtgtgac ctcatagtcc ttgtcgtcat ccttgagctt
     2401 gtaatcaata agaaattgtt ggaagctttc caagtggatc acaatgacat tttttccctt
     2461 accgattcca aaatattgag gatcaggtgc ggcgtagtgg ttcttgacat attgcttaac
     2521 atcgactaat tcttcagcgg ttgctccgtt acgctctttt tgtgcttgat aggtctggtt
     2581 tccgctgtaa atggtaaaag caggcaatcc aagcgctcta acgatatagg tatttgaaaa
     2641 tcctctagtc agaagctccg ggcggtcaat ctctgcaaga aacagattaa cagataagag
     2701 caagcaagac agtgctgtaa cagcaaagga agcccgcttg ttaaaaggac gcgggtcttt
     2761 tttgatggtc ttagttactg ataaactaat cagaatgatg aaatcaagga cgtaaacaat
     2821 atcccaaatg cgcaaaaggt ttaaagcaga gtctcctaaa ccagcagaaa ccttactact
     2881 ggctagcata gcactaaccg taatgaaatc tgaaaactct cggtaataaa tagaatttga
     2941 tattaacaag aggttaagga taatatagac gatccaagag ctgatataaa aggccctagt
     3001 attcttgata taaagggtaa atcccaatag taacaaagct agagggattg ggttaataat
     3061 tgttagaaag acctgatagg catttcccaa atctagtgaa aagtcagcat ggtaagccca
     3121 tagggttttt atccaaaagc agaagagaag cgttagcaca aagcctaatc ttgtattgat
     3181 aaagcttgtg ataaatgttt taaaa
//
LOCUS       DARYUW010000105         3091 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYUW010000105 DARYUW010000000
VERSION     DARYUW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3091
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            68..682
                     /locus_tag="TVW11_001913"
     CDS             68..682
                     /locus_tag="TVW11_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365977.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            693..2597
                     /locus_tag="TVW11_001914"
     CDS             693..2597
                     /locus_tag="TVW11_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1365978.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSHAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDI
                     VFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAII
                     REYNSYINGL"
     gene            2606..3037
                     /locus_tag="TVW11_001915"
     CDS             2606..3037
                     /locus_tag="TVW11_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1365979.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKVTELNDCLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIVLIDNILEQYEESKKGE"
BASE COUNT          994 a          620 c          728 g          749 t
ORIGIN      
        1 caatcagagt atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag
       61 ggttgacatg gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt
      121 tgttggccat ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt
      181 attgagtatt acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag
      241 atcccacagc aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc
      301 taagccaaag cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg
      361 tgtaatagcg gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa
      421 caaaactgtc tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt
      481 gtacttaata gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat
      541 aaatggcgtt aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg
      601 tctagtgaca atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa
      661 caaaatcacg ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag
      721 acgagacaaa cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc
      781 aagacaacca aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc
      841 tgatgattga gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta
      901 caggacaggc aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa
      961 ttaaactgga gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga
     1021 caaatgggct tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag
     1081 cagctggtat tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg
     1141 agactatcaa aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct
     1201 atcaagcaag tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag
     1261 ctgagattaa gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc
     1321 tatctgccaa gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg
     1381 agggcttacg ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc
     1441 aaatcagcgg cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca
     1501 aggatagggc aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct
     1561 tgcaagacgc agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa
     1621 ctgttagcga tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg
     1681 agcatcgtgt gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta
     1741 agctagcgat ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct
     1801 cagcgattaa tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg
     1861 gtaatacgac cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag
     1921 ccgatcaaat tattggtggt tcgattgacg ctgctaagat tagagtgatc aatcttaacg
     1981 ctagcagcat tgttggctta gacgctaact ttatcagagc taaaattgag catacgatta
     2041 caagtttgct tgagggtaaa gttatcagag ctcgcaacgg agcgatgatg attgacttgt
     2101 caaactctaa gattgacttt aacagcaacg ctaccattaa ctttaataac aaagacaacg
     2161 ctttggtacg taaagatggc acacacactg cctttgtgca ctttagccat gcgacgccta
     2221 aaaactatac aggatctgcg ctatatgcat ctattggtat tacctcgtca ggtgacggga
     2281 ttaacagtgc gtcgagcggt cgtttttgcg gcgctaggtt ttttaggtat gcgcgaggtt
     2341 acgagcacac agcgcttgtt gaccaagctg agatttacgg tgatgacatt gtctttagcg
     2401 acgactttaa tattgatcgt ggctttaaga tgaggcctag cctaatgcca aaaatggtcg
     2461 atctcaataa gatgtatcag gccattttag ctcttggccg ctgctggcta cacgctaata
     2521 atacagcgtg gacctttaac tcagacacta ccagcgcaat tatcagagag tataactctt
     2581 acatcaacgg attataggag acaacatgga tttaacagta caaaacaaag acttaaatac
     2641 gctctatagc gtactagaca aaattaaggt tactaatatg agagtaaatc gcggccgcgc
     2701 taagctgctt gccaaagtag aggctaagct cagagagtat gccaaagacg aggttgatat
     2761 tatcgatcaa tacgctgcta aaaacgacaa aggtaagtgg ttagttgatg acaaaggcaa
     2821 cgctaaatta gctgatgtca caaaagtaac tgagcttaac gactgtttag acgagttagc
     2881 caacgagcct atcgtcatca aaggccatga gtactctaag cgatttatcg actttttgga
     2941 gtatctggcc gaggccgaag atgagtttac aggggccgaa attgtactga ttgacaacat
     3001 tttagaacaa tacgaagaaa gtaaaaaagg agaataatta tggctagaaa ttggaaaatc
     3061 gtcggcaaat atccacaacc aaacgcgcta g
//
LOCUS       DARYUW010000106         3089 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYUW010000106 DARYUW010000000
VERSION     DARYUW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3089
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..1243
                     /locus_tag="TVW11_001916"
     CDS             <1..1243
                     /locus_tag="TVW11_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1365980.1"
                     /translation="TADKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQ
                     RANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEK
                     EELTTKLQELQKQAEEKTTEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQ
                     KEMELKQAQEQLKQEQKPHEGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKA
                     QLSETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAAL
                     QEQINKLKAEIEQKTKEIEALKQGMQSHQGQEKPKDPKTPETPKDPKTPEKNDQPQAP
                     EKRSVPWTALTPAKPIDTTKAPKSSAPSPQTGAATPKKQLPATGDTATPSFFTAAAMA
                     VLASVGVLNLSPRRKKNQNNR"
     gene            1660..2502
                     /locus_tag="TVW11_001917"
     CDS             1660..2502
                     /locus_tag="TVW11_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1365981.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(2605..>3089)
                     /locus_tag="TVW11_001918"
     CDS             complement(2605..>3089)
                     /locus_tag="TVW11_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1365982.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         1040 a          696 c          585 g          768 t
ORIGIN      
        1 tacggctgat aaagaaaagg cagagactga agctaaaaaa gcgaaagaag aagctaagac
       61 cgctaaagaa gctgctcatc aagaacaaga aaaagctaaa caattagaac aagctaatca
      121 acaggctaac caaagagcta atctggcaga aaaatctaaa aaagatttag aaactcaaaa
      181 agaaaaactt gaacaagaga ttaaagaagc tacagaagct aaaaacaaag ccgagcaaaa
      241 attaaaagac ctacaagatt cagctagtca aggcagtgaa ttgtctaaac agctgttaaa
      301 agaaaaagaa gaattaacaa caaaacttca agagcttcaa aaacaagctg aggaaaaaac
      361 aactgaaatt gaaaagctaa aacaagagct tgaagctaat aaacaaaaca gtggtcagct
      421 aggtcaacag gaacaaaagc ttcaagagca attgaataag gttcaaaaag agctgaaaca
      481 aaaggaaatg gagttaaaac aagctcaaga acagctgaaa caagaacaaa aacctcacga
      541 aggtggcgga gattctgacg cttccaaagc aagaatcact gagctagaaa aacaagttca
      601 aacactaacc aaggaaaagg cagatctgtc atcaaccctt gagtcaacaa aagctcaatt
      661 gtcagagact caagcaagac tatcagaagc tcaaaaacaa ttgactgctg ctcaagaaaa
      721 gttaacaaca cttgaagccg agaaaacagc gcttcaacat caagttgaga ccatttcaaa
      781 acagctatca gaaacacgtg accttagcga aaaggaaaaa gcagcactcc aagagcaaat
      841 caataagcta aaggctgaga ttgagcaaaa gaccaaggaa attgaagcct taaagcaagg
      901 catgcaatca catcaaggtc aagaaaaacc aaaggatcca aaaactccgg aaacaccaaa
      961 ggatccaaag actcctgaga aaaacgatca gccacaagcg cctgaaaaac gtagtgtccc
     1021 ttggactgct cttacaccag ctaagccaat tgacactacc aaagctccta agagctcagc
     1081 accaagccca cagactgggg cagcaacacc taaaaaacaa ttaccagcaa ctggtgatac
     1141 agcgacacct agcttcttta ccgctgctgc tatggcagta ttggctagcg tcggtgtcct
     1201 aaatctctca cctagacgca aaaagaatca aaacaaccgt taatgtagag actctcatat
     1261 ctggattgaa taacagcaaa cccgacatga gcaaaaacaa atgtctaacc aaaaatcact
     1321 gacattagta ctttaaccaa agcctttgag tcaagctaaa caggctgtcc tgcctattgg
     1381 cttgactcgt tttgtgattg tgaaacacac caaggtcaaa cctaccttgt cctccatttt
     1441 aaacctactc ttttctccca tacccacttt agcttacgca agaaggtgcc taatcatcac
     1501 ttttggtagc ttcgatgctc tatataaatg gatcaacaaa gataaatcat acaaaactgc
     1561 gagttgttcc tatagtcacg atagctctta cagatatgaa aagtaaatac agctattaaa
     1621 aatatggtac aataggggta cgatttttag gaggcatgta tggtttcagt tctttcacga
     1681 gtgattaagg gaataattat tgcgcttggc tttattttac cgggagtatc tggaggagta
     1741 ttagccgcta tccttgggat ctatgagcgt atcattgcct ttttagctca tatacgtgag
     1801 cattttgttg agaatgttct ctttttcctg cctgttgggg ttggtggtat tttagggatt
     1861 gccctctttt cttaccctgt tgactatctg ctcaagcact atcaggtacc agtcttatgg
     1921 ggcttcgctg gggccatcat aggaaccgta cctagcctga taaagacttc gacaaaaaca
     1981 tctcagcgtg accaagttga ttggctctgg ctagtattaa cctttgtcct atcaggactg
     2041 ggactttatt tcttaaatga tctcgttggg acaatacctg caagctttac cgcctttgtc
     2101 ctagctggtg ccttgattgc tttaggtatt ttggtacctg gtcttagccc gtctaatctt
     2161 ttattaattt taggacttta ctcacccatg ctgattggct ttaaatcact tgatttggta
     2221 ggaacctttt tacccattgc tattggtggc ttattaacca tgctagcttt ttccaagatt
     2281 atggattttg ctctcaagca ctaccattca cgcgtttacc actttattat cggtatcgtc
     2341 ctatccagca ccctgcttat tttaattcca aatagcagta ataaggaagc tatctcttac
     2401 gccggtgcag gtcttggcac ctggctaatg gctctgctat tatttggcct tggtgtctgg
     2461 cttggtctat ggatgagcca gcttgaggag aaatacaaat aacactcgat acaccagcaa
     2521 gtacctctaa cagcagcatt aagatcaaaa aaacgaatga ctagctctca gccttatcac
     2581 cagctgtgac tagcattcgt ttttttatat gtcatcatgc tgtcttgcct ctgtcacgat
     2641 ttctataaaa cggttcgtca attgagcagt tataccccag ataggctttt ctaaatgctc
     2701 atagagtaat acctgatctt gcatgtacct caacctgtac tgctctccat tagggatacg
     2761 atccaacgga aagtctgacg agattatcga ttgcatttgt aaaggataag caacaggagc
     2821 ttgcgccatg agctcctcca aaggcaccgt aaacaagcta tcaacctctt cattgaccct
     2881 aagccttctc caatcatcaa tagccagttc cgcaacaaag caatgaatgc tacgagtcgg
     2941 ctgaactaaa tagtcaatct ccccccaaac atgaacctgc tcaggctcta tattgagctc
     3001 ctctaccgtc tcacgaatag ccgcctgctg ataagtctca ccctcctcca cgcgcccact
     3061 aggaaaagaa acctcccctg gcttgaatg
//
LOCUS       DARYUW010000107         3065 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYUW010000107 DARYUW010000000
VERSION     DARYUW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3065
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(74..1432)
                     /locus_tag="TVW11_001919"
     CDS             complement(74..1432)
                     /locus_tag="TVW11_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1365983.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(1840..2070)
                     /locus_tag="TVW11_001920"
     CDS             complement(1840..2070)
                     /locus_tag="TVW11_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365984.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(2164..2577)
                     /locus_tag="TVW11_001921"
     CDS             complement(2164..2577)
                     /locus_tag="TVW11_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365985.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(2612..2809)
                     /locus_tag="TVW11_001922"
     CDS             complement(2612..2809)
                     /locus_tag="TVW11_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1365986.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
BASE COUNT          977 a          589 c          377 g         1122 t
ORIGIN      
        1 gaaaatatat cattcttgtt tactaccaac ttctaactag tatagtacga ggatataatt
       61 aaatcttcgt cttttacaac attttccaat ataacgctag tggtaacaac aataataatc
      121 caatagctga tacaatcgaa caatatattg tcattcttgc ttttgataaa ttttcatttt
      181 gtaaaaccac catcaagggt ggtgcctgaa atgggaaaaa tacacttgaa aaacctataa
      241 cttcaatatg acataaaaat gtttttgaaa cattactaac gcctgaaata ttatcaatca
      301 aaggtgtaac tactgccgga acacccggta aagttactat aaatcctaat ataatacaca
      361 atacaacgaa aaaagttaaa acattaaatg cacttgctgt ttccaaagaa acaatattga
      421 ttaaatgcac agcaatgaca tttgcaagtc ctgaagattt tgctatattc cctaaactta
      481 tgattccagc tacataaaaa aatggctcaa aatttatttt tcttaaaggt tgcttttcca
      541 taaaatttga atttggtaac attacaatca aggcagttgc cattcctgtc caaccggttg
      601 gtactttatg aatatgttct gtcatccaga aagacagagt tataaataac aaaactatta
      661 acaatttctg ctcttttgtt atgtcaatgg cttttttgga cacgcaaatc gaatctttac
      721 atcttctata aaataaccgc attgtaaaat ataaaatcaa tatttttcca actcctaaaa
      781 tagggaagta caagagaaag tatctgctat aggatatatt tatggagtaa agacttaaaa
      841 ttgctccagt aaaaacatta tttggaacat tggaaggtaa tacataaaat gcaggtatat
      901 aggttgctaa aacccctgac ataacaattc cttcccattc cttacttcct ttttcataac
      961 ctaattctaa agatagggca tttagaatag gtaaaagcaa aactactcta cccattgctg
     1021 atggcatcaa aaaaattagt accactccta gcaaaatcgt cccaaataac actttagaat
     1081 atttccccat gcacaccgga ataaaaaatc tcgcaagtaa tctatcaagt tcagtatgct
     1141 ttactgccgc ccctataata acacctgaaa taacaagcca tgctgcacct gaagttatcc
     1201 ctgataagat gacttgcttc tcagctatat tccctatcat acaagctgtc ataaataaaa
     1261 tgcttgtata ccatgcagga attatattgc ttgccaaaag gaagatagat ataagaatca
     1321 aaataaaaac tttctctata tttgaaataa atggtagtac agatacaaac aacggtaaca
     1381 ttgtaaatat ccactttata tgattattcc taattccaga ttttaaaatc atcctccatt
     1441 tttgacctcc aactctaatt tatttcatag tattatacca tatttatttt cattttatag
     1501 gtctacctct tgcttctttg tctgtgttaa tcgcttttct tgtttttata actgctctat
     1561 acaagtctta actttttctg cctgtttaat tttttctcgt atctctaata ttttattgtg
     1621 taagctcttt ttttctttct tcatattggc gacttccgat tttcatttgc taatgactaa
     1681 ggtcttgctt tcgcccaaat gctcttttag atatttcttg gcactctcaa ataaaataat
     1741 ctctgctgta tcaacgttag ctgatatgcc ctctgcaaga gccttcggag aacgcacgca
     1801 cctgttgagg tgtatatgta cactcttgta aacaagggac tattcctctg tgtccgttgc
     1861 ttcctcttgc acttctatgt tttcttctgt ttgttctctt ttctctatga tttttaggat
     1921 tttttgattg actgctccct tttcataaag gcgtctatct ctcttttttc tctcttcctg
     1981 tttcgactga atgatgggct tttttctttt gttttgtaac tgcttgattt ctccatctgt
     2041 cattaaaatt ttttcatcta tgtttttcat tttctatttt cctctctttc tgttttgagc
     2101 aacaaaaaaa cagtaaacca tttttttgat ttactgtttt ctaataaata ttatcttagt
     2161 tatctattct acttttcgta aatataaatg ataaatccat gatacgatac cacttatcaa
     2221 aacaactcca attatagaaa acccagaaac tttgtttaaa tagcccataa aaactagaag
     2281 aaaaaaaact attcccagta aagttgtttg aatcacatat cctaccatat tagccttagc
     2341 tgttattaag gactctcttt catcggtttc atttatccaa tcttgttttt tacctgaaat
     2401 tgaaaatacc catattccac taacacacag aagaatagca acaacgagaa agcctaccca
     2461 tgcaatatcc attcttggaa atacctgtaa aatatctttt ttaaaaaata atatgcaagc
     2521 aatcaaggca aaaagtattc cagtagcaat aactataata gctaactttc ttgccataac
     2581 catctctttt tttatatttc ttttcatttt tttattcctc ctcgtatata aagatatctt
     2641 caatgcttaa actaaaatac ttagcaattt taaaagctaa aataatggaa ggattatacc
     2701 ttccgttttc taaagaacca attgtctgcc ttgatacttc aagaatagat gctaactctt
     2761 cctgtgttat tccattttct tttctgattt cctcaagtct atttttcaca tttaatgacc
     2821 tcctgcaaca atgacaagct aactttacat atagtataat gttttttaga gaaaatggca
     2881 agtatacttt ccataaaatc gtttccttat aggtctagcc cttacttttt tacatgtacg
     2941 actcctctat atctgcattt tcctcttata cttctgtctg ttgatgagca cttgcttctc
     3001 tttgtgatga tatctttact atgcttttca tttttgggat ttttatctta attttgagta
     3061 gtcat
//
LOCUS       DARYUW010000108         2914 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYUW010000108 DARYUW010000000
VERSION     DARYUW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            47..1099
                     /locus_tag="TVW11_001923"
     CDS             47..1099
                     /locus_tag="TVW11_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1365987.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            1302..2318
                     /gene="adhP"
                     /locus_tag="TVW11_001924"
     CDS             1302..2318
                     /gene="adhP"
                     /locus_tag="TVW11_001924"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1365988.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
BASE COUNT          892 a          491 c          679 g          852 t
ORIGIN      
        1 aaaatgtaat cgattacatt ttctagacta aatttggaga cgttttatga aagcagctac
       61 atatgttgct ccaggtcagc tggagcttat tgatcaacca aaaccagaga ttcttgctcc
      121 gacagatgct gtggttcgtt tattgaaaac aacaatctgt ggaacagact tacatatttt
      181 aggtggagat gtcccagaga ctactcatgg taccatttta ggtcatgaag gtattggtat
      241 tgtcgagtca gtcggctctg cagtgaacaa ctttaaggta ggtgataagg ttattatttc
      301 ctgtatcaca gcctgtaata cctgctatta ttgtaaaaaa ggaattcctg ctcattgtga
      361 aagcggtggc tggattctag ggcatttgat taatgggaca caagcagagt atgttcatat
      421 tcctcaagca gatggcagtc tttatcatgc tcctaaaacc gttgaggatg atgccttggt
      481 tatgctgtca gacattttcc caacttccta tgaaataggc gttcagtctg caaaggtaaa
      541 gccgggtgat acagtgtgta tcgttggagc aggtcctatc ggactagcag ctcttttaac
      601 agcacaattt tattcaccag ctaagctgat catggttgac ttgtcagaat cacgtttaga
      661 agcagctaag cgctttggag caacagatac gatttgctct ggtgaccttg atgatattgt
      721 caaaaaagtc catgaattaa ctgatggtcg aggtgttgat gttgccattg agtgtgtagg
      781 ctatcctgct acctttgata tttgccaaaa gattattgct attggcgggc atgtttctaa
      841 cgttggtgtc catggaaaac cagttagttt ggacctacag gacctatgga tcaaaaacat
      901 tacaatgtca actggcctag taaacgctaa tacaacagaa atgctattga atgtgttgaa
      961 atctggtaag attgatgcaa ctaagatggt aacacatcac tttaagctgt cagaggttga
     1021 aaaagcctat gaggtcttta aaaatgccgg cagtaataac gcccttaaag tgattattga
     1081 aaatgacatt acagcctaaa ggaataaggt ataaatagat aaaagtgaca acagcatttg
     1141 gaatggtcta gatgctgttt tttagccaac ttaactggtt aagtttattt tcagaaaact
     1201 ttcaagaaat tggttgacaa accttgtgaa aaagtataca atacaaattg taaacggttg
     1261 caaaaataga taaaccgaga cttagaaatt ggaggcatcc tatgaaggct gtagttgtta
     1321 accaaaccag cagtggtgta gaggttgtag agcatgatgt accatcaatc ggtcatggag
     1381 aagctcttgt taaagtagaa tattgtggcg tatgtcatac tgacttgcat gttgcgcatg
     1441 gtgattttgg tcaggttcca gggcgtatcc tcggtcatga aggtatcggt attgtcgaaa
     1501 agctaggtga aggcgttacc tccttaaagg ttggtgatcg tgtatcaatt gcttggttct
     1561 ttgaaggctg cggtcattgt gaatattgta caacaggtcg cgagactcta tgccgttcag
     1621 tcaaaaatgc tggctattca gttgatggtg ggatgagtga gtatgcagtt gttacagctg
     1681 actatgctgt gaaagtgcca gatggtcttg acccagctca agcatcatca attacctgtg
     1741 caggcgttac aacctataag gctatcaaag aagcaggtgc cgctccagga caatggattg
     1801 ttatctttgg tgccggtgga cttggtaacc tagctgttca gtatgctaaa aaggttttca
     1861 atgctcatgt cgtagcagtg gacattaaca atgataagct agagctggcc aaggaggttg
     1921 gagcagatat cgttgtcaat ggtaaagaaa tcgaagatgt tgccggctat atccaagaaa
     1981 aaacaggtgg tgctcatggc gttgtggtaa ccgctgtttc taaagtagcc tttaaccaag
     2041 ctattgatag tgtgcgtgca ggaggaactg ttgttgctgt aggacttcca tcagaataca
     2101 tggaattatc tatcgtaaag actgtcctag acggaatcaa ggtagtcgga tcacttgtgg
     2161 gaactcgtaa agacttggaa gaagcctttg cctttggtgc agaaggtctg gttgtgccag
     2221 ttgtagaaaa ggttccagtt gagactgctc cagaagtctt tgacgaaatg gaacgtggtc
     2281 tcattcaagg aagaaaggta ttggatttca cgctttaagg ctgatttcag aaaaagtcag
     2341 cagccagaca agctgattgt cccaaatgat gaataaagtc cttagaatta attttctaag
     2401 ggcttttttg gtgaaactaa ctggtaaaaa aagcttggta tctaaagatg taaaagagcc
     2461 agctagttat taataccatg attgcccctt gaaagacagt accagagaaa gttggacata
     2521 ttgtaacctc tgatagagat actgggtttg aacaatatta gagattaaca caggaactca
     2581 atctagaagt ttatttctct gctcctcaca ccccttgata acgtaggaca aatgaaaata
     2641 ccaatgggtt aatcaaagag tagtttccta aaggaactga cttgactgat attgagagct
     2701 ctatcatata agagtgggaa gataaatgaa atgatcgttc tagaagatgt cctaactgga
     2761 aactacctta taaactcttt tatggaaaag cgttgcactt aatttgacaa ttcgtcttca
     2821 caaattttag gaagcactgt aggaaaaaag aataatgaca taacatattg ctaaaaacat
     2881 gggttataag ctaaattatt atctacgttt ttag
//
LOCUS       DARYUW010000109         2633 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYUW010000109 DARYUW010000000
VERSION     DARYUW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..911)
                     /locus_tag="TVW11_001925"
     CDS             complement(<1..911)
                     /locus_tag="TVW11_001925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365989.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPVETEGVYILSDRNYKDSNVIFYR
                     YGLIEPREKVFVNAVPILIGPNGEQWQDFQKCYFDLPHWIEDLQEKQILLSSYLSENY
                     QVESLLKQSNGGNIYKAIHLDTGKNVVIKECRSHIICTASISKKQLRDNEWNLSGLIT
                     NNIPKSIEKVHEWINDYYIYEYIDGQDL"
     gene            complement(1327..2193)
                     /locus_tag="TVW11_001926"
     CDS             complement(1327..2193)
                     /locus_tag="TVW11_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1365990.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
     gene            complement(2442..>2633)
                     /locus_tag="TVW11_001927"
     CDS             complement(2442..>2633)
                     /locus_tag="TVW11_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEL1365991.1"
                     /translation="NGMMESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYYNNKR
                     IKTKLKGLSPVQYRTKSFQ"
BASE COUNT          828 a          493 c          366 g          946 t
ORIGIN      
        1 agatcttgac catcaatata ttcatatata tagtaatcgt ttatccattc atgaactttt
       61 tcaatacttt ttgggatatt attagttatt agaccagata gattccattc gttatctctc
      121 aactgttttt tactaatact agctgtacag ataatatgag agcgacattc tttgataact
      181 acattttttc cagtatctag atgaatagct ttataaatat ttccaccatt agattgcttt
      241 agtaagcttt ccacttgata attttcactt aaatatgacg acaataaaat ctgtttttct
      301 tgtaaatctt caatccaatg aggtaaatca aaataacact tctggaaatc ctgccattgc
      361 tctccgtttg gtccaattaa tattggaact gcatttacaa aaactttttc tctaggttca
      421 ataagtccat acctataaaa aataacattt gaatctttat agtttctatc actaagtata
      481 tagactcctt ctgtctcaac aggtatcaat tcatacaagt cacttaataa ttgtttacag
      541 tgttctctat ctctgggata aattgtgatg aatttcccag attccgaagg atcttccata
      601 tcggatacat tttctaaaat cattttttcg tcttttaaat atttaaaaga aatatgatga
      661 cattttaaat acggaaatac tacagaaaaa attgctttat agttttgaaa tgttcctgaa
      721 atatgaattt taaatccata ttcaggtaaa acataatcat tcgtctctac atatctaaag
      781 cttgtcagat ccatatgctt caccatgtac cagctgaata aatgggtact tctctggatg
      841 ctccatgatt gtcttaactt tcttttccac gtaggcttca aagctttttt caaagctact
      901 tgaacactca cgagaatctt ctttatagat acatttttaa gtaatcattg gttttctcat
      961 agcaatacat ctcctcagtc ttattagtat aaaactaaaa acgctcacat taacaggtct
     1021 ttttgagcgt ttttagtagg actagttact aaattatggt ttgtagattg gacatttcca
     1081 agtcacaaca aagcctttca ctggcgcaaa gcatctacta gcctcgtatg caaattgagt
     1141 catgtttgtg atctcctttc attcttgatg agtctagtgt atcatcaaaa accgtaccaa
     1201 agctaaactg ttcatatgtt caaatcatgg ttttgacatt aatcaaaaaa cagtagctca
     1261 aaaagccact gtttgctact agctaagcat ctaaaccatt ttgcttatca atgctttaag
     1321 ttgcatttat tcaacttcct ttaaccattt ctctaaacta tctgaataat aggctgcact
     1381 ttcatcacaa tttaatgcct ttaagatgtg tatggcgtca tttatttgct ttaagcctag
     1441 ttccttttcc cctttacaat ataggtgctg accatcagca atcatataaa caattcttaa
     1501 gtaggtgtca ttttcttcaa aaaaatgatt gttaatcatt ttatcaaaat atgcagctat
     1561 acctagcctt ttttcctgag tagctttaaa cagcccattt aataaaatgc tgtgcactaa
     1621 atttcgatgc tgccaaagct cctcaaaaaa gtctactctt cctagcattt ctcgagtata
     1681 ccgcaaatac acatccaagg ataataaggg agaaatatct gaaaataatt gtaattcgta
     1741 tattccccaa atctccactg aaaacaaata atcatataaa aagctttgct catctggagt
     1801 cattttgata ttctcgtcta aaaagagcat ttggctttta atcatcaaag catttaaaaa
     1861 atagatatcc tttttgtata aatgatactg ctccagctct tttgtataca attgatgtaa
     1921 gctggacagg tctttttttg atatggcctc ccagatctct tgctttagga cagcatatgg
     1981 ggaaggctta aagccatttg ctagatagat aaattcattg agctctgtcc gaatattgct
     2041 aagtccaacc aatagctttg agattgttat atcggattca ccattttcaa atctgcttaa
     2101 catcgagtga gaaaagtcat ctcccgtcgc ttcctttaac gatatgtgtc gcgatgtccg
     2161 cagtaattta aacatttctc ccatatattg catatcaata cctcttcaat ctttcatttt
     2221 agtatagtat ataaccttaa aaatgtaaat ccagtcttga ttgcataaac ctttaattca
     2281 acgtttgatg ctactaaata tcctattttt ctgaagtaga tcctcatctt tatgctataa
     2341 gcacttgctg cgttttagaa aatgggctaa atcagctata ctccttttta ataacaaaaa
     2401 agccttattt atgtactgcc cccaaaaagt tgaacgaata attattgaaa ggatttagtt
     2461 ctgtattgaa cagggctaag tccttttagt ttagttttga ttcgtttatt gttgtagtaa
     2521 aagatgtatt cagtgattgc ttgttcgagc tcatccagtg agtggtagga tttctcaaag
     2581 ccatagaaca tctctgactt taaaatgcca aagaaggatt ccatcatccc att
//
LOCUS       DARYUW010000110         2589 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYUW010000110 DARYUW010000000
VERSION     DARYUW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            18..98
                     /locus_tag="TVW11_001928"
     tRNA            18..98
                     /locus_tag="TVW11_001928"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TVW11_001929"
     tRNA            105..175
                     /locus_tag="TVW11_001929"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TVW11_001930"
     tRNA            187..259
                     /locus_tag="TVW11_001930"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TVW11_001931"
     tRNA            268..339
                     /locus_tag="TVW11_001931"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TVW11_001932"
     tRNA            358..441
                     /locus_tag="TVW11_001932"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TVW11_001933"
     CDS             complement(785..1915)
                     /locus_tag="TVW11_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1365992.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2480..>2589
                     /locus_tag="TVW11_001934"
     CDS             2480..>2589
                     /locus_tag="TVW11_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1365993.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKA"
BASE COUNT          825 a          477 c          529 g          758 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa aacgaaacta cggagagaac ctaataactg gctatttctt
     2401 gatataagcc agcgtgttaa aatcttcttt gggagaaaat ttagaaaaaa ataatatttc
     2461 tatcactaag gagagaaaga tgacaactaa agaaaaacaa acaaaactaa tgcgcaggta
     2521 tggcattttc tcggtagtcg ttgccctaac agctctagca ggtctaggag cagctaatga
     2581 agttaaggc
//
LOCUS       DARYUW010000111         2514 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYUW010000111 DARYUW010000000
VERSION     DARYUW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2514
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..1512)
                     /locus_tag="TVW11_001935"
     CDS             complement(<1..1512)
                     /locus_tag="TVW11_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1365994.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILA"
     gene            complement(1579..1884)
                     /locus_tag="TVW11_001936"
     CDS             complement(1579..1884)
                     /locus_tag="TVW11_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365995.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(2051..2368)
                     /locus_tag="TVW11_001937"
     CDS             complement(2051..2368)
                     /locus_tag="TVW11_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365996.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(2350..>2514)
                     /locus_tag="TVW11_001938"
     CDS             complement(2350..>2514)
                     /locus_tag="TVW11_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1365997.1"
                     /translation="VQDFQDYTQSKVSKLSALATDFENLNRDIQTVIDSKLETDRQLA
                     GEFRAWQTEL"
BASE COUNT          803 a          472 c          374 g          865 t
ORIGIN      
        1 tgccaaaata aaatcgttat tttctatcat tttatcagta tctagcacaa cgactatatt
       61 atccttacta tctgtcacac tttccaaagg tagattatct ttattttcag gaacactact
      121 accattttca ttgaaataga aaaattcttg cccatcagga atgacttgca ccgtaaggtc
      181 atcttttgta tagtttgtac cagtaaattg ttctgctaca actgtattct cgattgatgc
      241 cttattctct ttaaatttat gaggaatata gatggttgct attttattat ctaatgattg
      301 atagttcgtt ccattaactt tattttgtac cttagcacct gtttgattaa tataaaccag
      361 ttccttatta acttctggat gcgttattcc atcacttttt aattgcttag aaaaatcttc
      421 tgtaacatca gaagctgcca tatattctgg aacataggct gaagatgatt tgatatatat
      481 aaaatccagt ttttttaagg ctttagcaat ctctacgtac ttagctcctg agtcatttgc
      541 ttcttctcca ttagtaacag attcattttc aatacccaaa aactctggtc ttttccaatc
      601 ttttactgca ctccatggtt ttaaatgctt tatctgcatg tttatctttg attgactagc
      661 ctttgtttcc cgtaaaaaga ctcctgaaac aactattatg atagaaataa ccgcaagcca
      721 tacgataaaa atgaggctat ttttggcctt attttttata atttcaatag gtttttcaac
      781 cttaatagtt agccaaaata gaacaaaggt gatgatgtca atgatttgaa atatgatcaa
      841 attagttaaa agcatagaaa aaaataactt ggaactgtag gtgaaaaaac cactacccaa
      901 aaaagaacta taagaaatca tcaataaagc ggccataacc agttcaaaag taaatgacat
      961 gaaataatct cttcttaggt cgtgtacagg taatcctaaa gaacgtctta tcactccttc
     1021 tttaatctgt ctcgctctaa caacaaatag aacaactaat aaggttaagt aaattgaaat
     1081 cattagcaat aatctcaacg gaccagtaaa ttgtatcatt ccccctatct gccaagggta
     1141 agccagatat atgacttgaa gacctgtaga tgtgagcggt tttaaactat ttgaatctaa
     1201 tttccctagg gtataataca tccctgtgat tggtgcagac tttaattgtt catgattagt
     1261 attatcaaac ttgatataag tcaactgccc cgaattttga actaccggtt tgtaaatggt
     1321 aacttttttc tcttttgata ggtcactaat cgtttgatac acttcttcat tagaaagatt
     1381 gcttttccct tgaatggaga aggcaccatc aattggtaaa ggtattggtt tttgagtatc
     1441 attaatacta accagaccaa tggcagcaat taaacaaaag aagaatccaa caatgcataa
     1501 ttttaatttc ataagcacct acctatatca taaaaggccc tatagcatta ttgggccttt
     1561 agctttcata aaccattttt aaaatgtaaa gtaattccaa tgtgtattta atcgaacatc
     1621 attccagctt tttgttgcgc ttgagtttgc ccatccatat ttttgagaat ctctatcctt
     1681 aactgttccc catagattag ttactgaaga ttttgaacca atattatttg gagacttaac
     1741 atagtcatta gaataaccat agttatcact tacaccataa ttccattcat caataattgg
     1801 atatggagct ggatgcgctg ttgctgcact aacaactcta gctgtagcag cagatccaaa
     1861 acttaaagtg cttacagcaa gcaaaactaa tgttttgtca ccaatttttc atattagttc
     1921 tcattggata gattgttaaa aatatttgaa caatctaaat aatatattat tatttattag
     1981 cataatatca tattattatt tgaattacaa gatgctaaat tgcaagtaaa agttagtcat
     2041 cctatagaaa ttatccgagt gacttgttgt tcaaaatttt ccccaatttt aaaaagagat
     2101 gaaactctgc gttggattga tcctttaagc gacccaattc attgaaaaaa tctgatgcag
     2161 cattggcaga taggtctaaa cgcttcaaaa aaacactcat cttctggtac tcagagttga
     2221 tcaaatcatt taagacatgt cttctttcag ataagctgtc ttcacgcttc tgataggctc
     2281 ttttctggcg tagaaagtcc tgctcggcat catccatctc ccgaagctta cgataaatag
     2341 ccacttcctc tacaattctg tctgccatgc tctaaactct cctgctaact gacgatccgt
     2401 ttcaagcttg ctatcaataa ccgtctgaat atctctattc aagttttcaa agtctgtggc
     2461 caaggctgac agcttgctga ccttggattg agtatagtcc tgaaagtctt ggac
//
LOCUS       DARYUW010000112         2472 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYUW010000112 DARYUW010000000
VERSION     DARYUW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            50..1003
                     /locus_tag="TVW11_001939"
     CDS             50..1003
                     /locus_tag="TVW11_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1365998.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1063..2262
                     /locus_tag="TVW11_001940"
     CDS             1063..2262
                     /locus_tag="TVW11_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1365999.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          745 t
ORIGIN      
        1 ggctagtggt attcttttca tttcagcctt attttgatat gatagacgta tgaattttga
       61 aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg aaaatgattt
      121 aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg gagcccaagg
      181 agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagt taaccaagga
      241 ggagtggcgc caggcttatc agtttgtttt gatcaaggct gggaaaacag agccattaca
      301 ggccaaccac caatttaccc cagacgcgat cggctttatc atgctttata ttttggagac
      361 cttgagctca caagagtcac ttgatgtgct tgagattggc agtggaacag gtaatttagc
      421 tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg agcttgatga
      481 tttactaatt gatctatcag ctagtatcgc tgaaatcatg gggtcatcag cccagtttat
      541 tcaagaggat gctatcagac ctcagctgtt aaaagaaagt gatctcatca ttagcgattt
      601 gccagttggt ttttatccta acgacgatat tgctagcagg tatcaggtgg ctagctcaga
      661 tgagcatacc tatgcccatc atttactgat ggagcaagcc ttaaagtacc tgaaaaaaga
      721 tggctttgct attttcttag caccggtaaa tcttttgagc agcccacaaa gtcacctctt
      781 aaaacaatgg ctgaagggct atgctcaggt tgtggccttg attactttgc ctgaggctgt
      841 gtttggaaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat cgaatcgctt
      901 tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg ttcgtgattt
      961 tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taagagaatt ttttgatata
     1021 atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa gacaattgca
     1081 attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga ggaaaaggta
     1141 ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac tgttaaatac
     1201 gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc tgttaagcgc
     1261 ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat cacaggtgtt
     1321 gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggttgt tgatgataag
     1381 gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc gggggcagca
     1441 gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg tgtgtttgat
     1501 acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc tcaaaaatat
     1561 tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa atatgttgct
     1621 gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat tacagcccat
     1681 gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga tacctctatg
     1741 ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat tgatcctgct
     1801 attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga tgtggtcaat
     1861 atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga tatgcgtgat
     1921 attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa tatctttatc
     1981 gatcgtatca agaaatttat cggacaatac tttgcggtat taaatggtgc agatgccttg
     2041 gtctttaccg caggtatggg tgagaatgct cccttgatgc gccaagatgt cgtcaatggc
     2101 ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta tcgtggtgat
     2161 atttcaacag cagcttcaaa ggtgaaggtg cttgtcatct caactgatga agagctgtgt
     2221 attgcgcgtg acgttgaacg cttgaaacag actatatcat aatctgataa tatactctta
     2281 gctcagctga tcagttttaa agagtccaaa aaatactttt aattggtacc gacctccaaa
     2341 agttagactt aaaggtttaa cgattggagg tcggtattat tatatagcca aatattctca
     2401 agacaaagac agccaaaaaa tgagacggtc gtaaccgtct caaaaaagtt taatttaatt
     2461 aaaaacattc at
//
LOCUS       DARYUW010000113         2343 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYUW010000113 DARYUW010000000
VERSION     DARYUW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2343
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(69..905)
                     /locus_tag="TVW11_001941"
     CDS             complement(69..905)
                     /locus_tag="TVW11_001941"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366000.1"
                     /translation="MNNLYATINKLNKVEQSVFLVINDIIDNNTVFPDVNARNSLKKI
                     AISTLGDRTFSTPYDFISEHIYNNADLNSVQDDEMLVKNIEILKNYALQNNFENFDYS
                     LFIKNLNKIHRHYKLALIQKNFILRTTTEVEERAHDLKDKTKAIEQKMFKFDEIKSSI
                     YTDFIAILGVFSAFVFVMFGGIDVARAIFDIGSDLQTLDLSRMITIASLMLIGILTLM
                     YSLLLWIARITGKNFGNCYSSKCDNGCQHKWRHFLMRHSFYFSLMGLLIVVILFSHYV
                     FK"
     gene            complement(909..1451)
                     /locus_tag="TVW11_001942"
     CDS             complement(909..1451)
                     /locus_tag="TVW11_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1366001.1"
                     /translation="MTEALFVANYIIEYCNDHNLEINNLRIQKLLYFINARNLVENGS
                     PLFQDKIEKWKFGPVVPKVYHEYKRFGASTITKDDISAQIWKFNFEVSPFGEESPIEV
                     LTYNKEEFSDSQIQLIESTILALKKYSTFKLVDLTHEDDMWKSDNQLIMSGEKGLTYD
                     NNEIRDFFMSHIESQIWNNI"
     gene            complement(1586..>2343)
                     /locus_tag="TVW11_001943"
     CDS             complement(1586..>2343)
                     /locus_tag="TVW11_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1366002.1"
                     /translation="ALKTNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLP
                     CFIVKNWFGIDLWGNAIDLLNSASAQGLEIIYNAPGVNPRAGDLFVMEVAGSPYGHTG
                     AVIEDSDGYTIKTVEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTKQTVDT
                     APQTSDTIVETPKTGTFTVDVAEINIRRWPSLASEVVGSYKQDDTVSFDSEGYANGYY
                     WISYVGDSGKRNYLAIGQTDKDGNRISLWGKLN"
BASE COUNT          746 a          459 c          351 g          787 t
ORIGIN      
        1 aagaaattaa aaaaaataat tccttaaaaa acacaaaaaa ccgccctcaa tcaagagagc
       61 ggttggtttt atttaaacac ataatgacta aaaagaatta caacaattag taatcccatt
      121 aaagagaaat agaaagaatg tctcatgaga aaatgacgcc atttatgctg gcacccatta
      181 tcacattttg acgaatagca gttaccaaaa tttttgcctg taattctagc tatccaaagc
      241 agtaaagaat acataagcgt caatatacca attaacatta agcttgcaat ggtaatcatt
      301 cttgataagt ccagagtctg aagatcacta ccaatgtcaa atatcgctct cgctacatct
      361 atgccaccaa acataacaaa aacaaaagct gaaaacacac ctaagatagc aataaagtct
      421 gtgtaaattg atgattttat ttcatcaaac ttaaacattt tttgttctat agcttttgtt
      481 ttgtctttga ggtcatgggc tcgctcttcc acctctgtag ttgttcgcaa aataaaattc
      541 ttttgaatta atgctagttt ataatgtcta tgaattttat ttaaattttt gataaacaaa
      601 gaataatcaa agttttcaaa attgttttgt aatgcataat tttttaaaat ttcaatgttt
      661 ttaacgagca tttcatcatc ttgaacactg tttaaatcag cattattata tatatgctca
      721 gaaatgaaat cgtatggtgt actaaaagtt cgatcgccaa gtgttgaaat agctattttt
      781 tttaaactat tgcgagcatt tacatcaggg aaaacagtat tattatcaat aatgtcatta
      841 attactaaaa aaacagattg ttctactttg tttaacttat taatagttgc ataaagatta
      901 ttcatttgct aaatattatt ccatatttga gactcaatgt gcgacatgaa aaaatctctt
      961 atttcattgt tgtcataagt taaacctttt tcaccagaca ttatgagttg attatcagat
     1021 ttccacatat catcttcatg tgtcaaatct actaatttaa atgtgctata tttttttaat
     1081 gcgagtattg tactttcaat taattgaatt tgagaatccg aaaattcttc tttattatat
     1141 gtcaatactt caattgggct ttcttctcca aaggggctta cctcaaagtt gaatttccaa
     1201 atctgagcag aaatatcatc cttggtaatt gtagacgctc caaatctttt atattcatga
     1261 tagacttttg gaacaaccgg tccaaatttc catttttcta tcttatcctg aaacagtggg
     1321 ctgccatttt caactaagtt ccgagcattt ataaagtata aaagtttctg aattcttaaa
     1381 ttatttattt ctaaattgtg atcattgcaa tattcaatga tgtaatttgc tacaaacagt
     1441 gcctcagtca tccagtccac ctcctttttt taattataac atatttgtca agtactatat
     1501 cttgttagct aactttttag ctaacactac atattgattt tgataataaa aacagccccc
     1561 gcaaaagcga gggcgtttgt cttatctaat ttaatttacc ccaaaggctg atgcgattgc
     1621 catctttatc tgtctgtcca atagctaggt agttacgctt gcctgagtcg ccaacatagc
     1681 taatccagta gtagccatta gcgtagccct cgctatcaaa actgacagta tcatcttgtt
     1741 tgtagctacc tactacttca ctcgctaggc ttggccaacg tctgatattg atttctgcga
     1801 catctacggt aaaagtacct gtttttggtg tctctacgat agtgtcagac gtttgcggtg
     1861 ctgtatctac tgtctgctta gtgtgatcaa ccggtaatct aatccagccg acaacaccag
     1921 taaagtcacg agtattaaag cgagcgggac cacctacctg aagactatcc cagttaccgt
     1981 caatattttg ctcaacggtt ttaatagtat agccatcact gtcctcaata acagctcccg
     2041 tgtgtccgta gggactacca gctacctcca tgacaaataa gtcaccagct ctaggattga
     2101 ctccgggagc attatatatg atctctagcc cttgcgcaga tgcactattt aacaggtcaa
     2161 tcgcattacc ccataaatca atgccgaacc agtttttgac gataaaacat ggcaagtccg
     2221 cacactgcgt cccaaaacag ccatctttat caacacccat gcctgaattg gctaggtcga
     2281 cacagtattg tacaatctca tttgcggttg tcatcgttac ctccttatta gtttttaagg
     2341 ctt
//
LOCUS       DARYUW010000114         2292 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYUW010000114 DARYUW010000000
VERSION     DARYUW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2292
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            130..561
                     /locus_tag="TVW11_001944"
     CDS             130..561
                     /locus_tag="TVW11_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366003.1"
                     /translation="MVVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            776..1189
                     /locus_tag="TVW11_001945"
     CDS             776..1189
                     /locus_tag="TVW11_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366004.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            1173..1427
                     /locus_tag="TVW11_001946"
     CDS             1173..1427
                     /locus_tag="TVW11_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366005.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            1443..1844
                     /locus_tag="TVW11_001947"
     CDS             1443..1844
                     /locus_tag="TVW11_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366006.1"
                     /translation="MMKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQE
                     RAAIYLSNTYENIHKIKIIGIDKNLKTGSMNIATIVNSKYYISVTFMGGEIYTGVEQA
                     SKDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            1847..>2292
                     /locus_tag="TVW11_001948"
     CDS             1847..>2292
                     /locus_tag="TVW11_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366007.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT          885 a          304 c          445 g          658 t
ORIGIN      
        1 aatattatac cattattata gtataatatt tataatcata ttataatatt aaaatatctg
       61 gtgtctagct gtttttgtaa aagcaaaaaa cctgcaccac cttatgataa agcataaagg
      121 aatataagca tggtagtcta cctaaagcaa cacaaaaatt actggaaatt agtcagcata
      181 gcagctttaa tcattatttt aggaggaata ctaacaatga attggcttaa tggggatagg
      241 gacaataaag gcgagaataa ctactatcaa gtagagaagg atttagcaat ggaaattgtt
      301 agtgagtttg aaggagtaaa agagattagc tttcttagtc cagtacaatc caaagaaaca
      361 gggtattggg gaacaacagc tactataaat aaaactaatg agatatctta ttctttttcg
      421 atgacttttt caggaaagct tgatgattat tcttactatt acgataaatg ttttaaatta
      481 gtgaagcgtc acaaaaaatt gacattaagt caagtggatc taacagatat tgatattaaa
      541 tattctaagg gagggaaata aatgataact gacaaaaact ataactggct agctggaaaa
      601 gtatatgatg ttgatgctaa taaagtaact attcctgtta gaaaaaatac ggatattctt
      661 aatcgttatg tcaaagtcct tgaagccgaa gacaatcctg acaacggtat gcagtttacg
      721 gtgtcaaaga gtaataggaa tgttctagct ttaaattata aactaaggag cttctatgac
      781 agtaaaaaag aaagtcatca ttttattagg aatggtagca attttagtaa tgggaggtat
      841 atttatgttt agctataatc agaatcaagc gaaaatgtta gaacgacaat ttaaccatga
      901 acaaaaacga attgtcttgt atttgttaaa tcattatagc ggaattaatg agatagaatt
      961 taatgatatt gaaaacaaca gtacaacagg ttctaagaat gtattgctga caataaataa
     1021 taaaattaaa atggaagtta cattttttaa tttaaatgat gatacagata actatgttat
     1081 tagttggaat gggaaattaa gtttgataga caaaaatcct ataactcatt taagttcaat
     1141 agataaaata aaagtaaaat attggagtaa caatgatagt aacagataaa aattataatg
     1201 atatagccga tggggtttat aaggttgatg ctggcaaagt tattagacct tggcgaaacg
     1261 gtaagacttt taaaactaac gggaaagatt accgcgtcct caaaacagaa gacaaccccg
     1321 acaatggtat gcaggctatt gctgtagctc cgattaaggg tagtgaggtg ggtaagagtc
     1381 atatcatgat tgtttatgta aaaagcagct attggctagc gtcctagcaa taaaaggagt
     1441 tgatgatgaa aaagcaacaa agcaaacgac ggaaactaat tggcatagtg gctttaataa
     1501 caattttagg aggaatacta acaatgaatt ggtttaatga cgaaaaacta aatagagagc
     1561 gtagagaaca agagagggca gctatttatt taagtaatac atatgaaaat atacataaaa
     1621 taaagatcat cggtatagat aaaaatttaa aaacaggttc tatgaatata gctacaattg
     1681 ttaatagtaa gtactatata tccgtaacgt ttatgggagg tgagatttat acaggtgtag
     1741 agcaagcttc aaaagacaat gaggaatttt taaatcgtcg aaaaaaagca gagaataaga
     1801 caaccttgag taaggacatt gaagttattt ataaggagaa atagtagtgg ttagtgataa
     1861 agattataat aaactctctg aaaaagtata tgatgttgat gctaataaag taactatttc
     1921 tgttagaaaa aatacggata ttcttaatcg ttatgtcaaa atcctcaaag ccgaagatac
     1981 ccccgacaat ggtatgcaag ctatggctgt tgtaccaata aaagatggca aagaggatag
     2041 aagtcatatc gtcattgcct atgccgggac aaatagcagt gatatacgcg atattgacac
     2101 cgatattcaa tccgttgttt ttggagatga tcaatacctg tgtacccatg aggagcctga
     2161 ttcttttaaa gtggtcaaga gtcagctaag tactgctaaa gccttttccg actacattag
     2221 gacaagctac cctaacgctg ccatctccta caccggacac tctctgggag gctatctggc
     2281 actcatcaca gc
//
LOCUS       DARYUW010000115         2217 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYUW010000115 DARYUW010000000
VERSION     DARYUW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2217
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVW11_001949"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVW11_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1366008.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVW11_001950"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVW11_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1366009.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGDFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          556 c          390 g          645 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagt caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagctg
//
LOCUS       DARYUW010000116         2134 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYUW010000116 DARYUW010000000
VERSION     DARYUW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2134
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..857
                     /gene="galU"
                     /locus_tag="TVW11_001951"
     CDS             <1..857
                     /gene="galU"
                     /locus_tag="TVW11_001951"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1366010.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDLTDYIIKLGKAL
                     ESTQQQTK"
     gene            complement(964..1356)
                     /locus_tag="TVW11_001952"
                     /pseudo
     CDS             complement(964..1356)
                     /locus_tag="TVW11_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(1353..1880)
                     /locus_tag="TVW11_001953"
     CDS             complement(1353..1880)
                     /locus_tag="TVW11_001953"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1366011.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          631 a          533 c          467 g          503 t
ORIGIN      
        1 tcctgcctgc cactaaggca ctggccaagg aaatgctccc aatcgtcgat aagccaacca
       61 ttcaattcat cgtcgaggaa gccctaaagg ccggtatcga ggagattctt gtcgtcaccg
      121 gcaaggccaa acgctctatc gaagaccact ttgactccaa cttcgagctc gaatacaatc
      181 tccaagccaa gggcaaaacc gagctgctca agctcgttga tgagaccact gccatcaacc
      241 tgcacttcat tcgtcagagc caccctagag gactagggga cgctgtcctc caagccaagg
      301 cctttgtggg caatgagccc tttgtggtca tgctaggaga cgacctcatg gatattacca
      361 atcctagtgc caagcccttg accaagcagc ttatcgagga ttatgactgt acacacgcct
      421 caacgattgc tgtgatgagg gttccgcatg aggaggtttc caattatggc gtgattgcac
      481 cgcaagggaa ggctgttaag ggcttgtata gtgtggagac ctttgttgag aagccaagtc
      541 ctgatgaggc acctagtgac ttagcgatta ttggacgtta tttgttgacg cctgagattt
      601 ttgccatatt ggagaatcag gcgcctgggg ctggcaatga ggttcagctg accgatgcga
      661 ttgacaagct caacaagact cagcgggttt ttgccaggga gtttaaggga gagcggtatg
      721 atgttgggga caagtttggc tttatgaaga cctcacttga ctatgctctc aagcaccctc
      781 aggtcaagga cgacctcact gactacatta taaagctggg taaagcacta gaaagcactc
      841 aacagcagac aaaataggag ttggggcaac cgtcctagaa gcattaaaaa gcaacagcag
      901 caaaaccgtt gctttttgtt taaatcaaag atacacctgt cctagcactt ataagcttga
      961 aggaaaaaga ccaaaaagag aggtggaagc acctgctgct acggtatctg gtgtcagcca
     1021 catgataaaa gcattcccca taatccctga acacacatac agcagcaaaa actgtcttga
     1081 cccccaaatg gtctcagcca tccgcccgac aaaataaagg gttaaggtat taatgaaaaa
     1141 atgctcaaag ccaatatgaa ccactatagg tgtcaccaag cgccaaagct gatcaggcat
     1201 tgctctgaca acaagaccat tcatgccacc aaatataaca acagcataag ggtgcgtagc
     1261 aaactggcca tagaccagct gcattatcaa aaaaactaaa ccagtcaagc ccaagaaaaa
     1321 gagtgttatc gggtattttt tgatcatcag tctcattggc aatacacctc cttcacagca
     1381 atatcatgtg cctctaccac aaaatcctcc cactgacagg cataaatcgt gctaaaggta
     1441 gccccctgat aatccctcaa ataacgatca tagtagccac caccatagcc tatacgatag
     1501 cctgcagggt gaaaaacaag ccctggcaca tgaatggcat caatctccga cttagcaaca
     1561 gctatggtac acctaggctc cataagacca aaagccgtct gtatcaagtc acaaggatca
     1621 taagccacaa acaccatctc tccacgagaa cgagtcttgg gcacaaggat agtcttgccg
     1681 tcctgcaagg ctcgctcaat cagtagatgg ctttgatact cgtgtggcaa gggcagatag
     1741 gtcacaagag tctgcgcctc ttgatagctg ctactagcaa ctactgctgc caatagagct
     1801 aagtcctttt ccagcttatc ctctggggtc atcatggcta ggcgctgaag cactagttgg
     1861 cgataatctt ttttaatcat gcccatatca taacacaaag cgctgctact attcaagaat
     1921 cggccacaat caaggttctt tccttagttg tcctaccaga cagggcagca gctcaatcag
     1981 tgaatgtcct tcttacttct tgaggtgagc ttgtggtctc atgagatcaa aaaattattt
     2041 ttctaggtta agaaaagttt aagctttatg ctatacaccc gactttatca cttgttttag
     2101 tccacacctt actcaacccc ttggtagagt aagg
//
LOCUS       DARYUW010000117         2119 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYUW010000117 DARYUW010000000
VERSION     DARYUW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2119
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            101..1528
                     /locus_tag="TVW11_001954"
     CDS             101..1528
                     /locus_tag="TVW11_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1366012.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            1794..2063
                     /gene="rpsO"
                     /locus_tag="TVW11_001955"
     CDS             1794..2063
                     /gene="rpsO"
                     /locus_tag="TVW11_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1366013.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT          733 a          374 c          478 g          534 t
ORIGIN      
        1 aattaaagca atagcgcttg tcgaaaaact aatgttctct taatatcagg tagccatgcc
       61 aagggttttg tgttaaagta taggacgttc aaaaaatgaa atggagagac taatgagaac
      121 acaattgaaa aaattgctgg caggaacagc agcaggtacc ctgctgctgt ttaacctgac
      181 ctgcggaatg attaatgctt ttgcagagca gtattacggg tggagtgacg ggagtagcag
      241 ctatccgagt gctttgtatg ttacaccggt aggagatact acgaaaaaga tagctattcc
      301 tgtttattgc tttgactata agtttcagga gccacttgct tggaaagaaa taactcaacc
      361 gtcacacttg attgtctatg ataagtatga tggcaaaaat ttgatggcag cactggttga
      421 aaaacctaat atggtaagct atgagactaa aactaaactt caaacacttt taaagacaaa
      481 gtcaaatcta ataactgcaa ttttaagtag aggttatcca aacaaaagtt tttttgataa
      541 gtataaaaaa ttaactgatg aagataaaag acgagtgaca caatgtgctc tttggtatca
      601 tactgacaat atttcagaac aagatcttat cacaaaacat ttggatgggg attcaggtga
      661 aaaaagtcaa gcgctaaagg agttaatagg ggttgtaaaa aatacttcta atgagttagg
      721 agagggatta accttctata ctcgttataa tgatagatat ggtcctaaat atcaaaacct
      781 aataggctca attattgttc ccgaagagcc tcagaatgat cttgaaattg gtggtggaaa
      841 tgttattgat ttaaactacc aatctggacc aatggtagaa gaaggtggtc attcaggtgg
      901 caaggaagag gtcgaggaca ctaaaaagcc tgatgtgatt attggtggtc agggaagcgt
      961 tactgagact actgaggata ctcaaaaggg tatgagtggc agtactgaga ctcagccaga
     1021 ggttgaggat actaagcagc cacaatcaga tattatccta ggcggacaag gcaatgtgat
     1081 tgacacaact gaaaataccc aagagggcat gggtggccaa tcaggtgata ctacagagac
     1141 tgaggatacc aagcagccac aatcagacat tatcctaggt ggacagggca atgtaattga
     1201 caccactgaa aatactcaag agggtatgag tggttccaac aatggtcaaa catttgagga
     1261 ggacacacgt cctaagctgg aattccattt tgataatgaa gtgcctaacg atgatgacgc
     1321 tcctaaacca gagcaaccag aacagccaga gaagccggag caaccaagga agccacagca
     1381 ggagcagcaa agcctgccac gtccaataga gggcaaccag tcattgccaa aaacacatga
     1441 ggcaaaaggt gtactggctc tagtaggagt aggaatcctt gctatgctag gactaggctt
     1501 ttggtttaga ccttatcaaa aagactaaat caaggctcag cagctattta agctaaacag
     1561 ctgtgctcag ctaaatgata aaacaattaa gattggagaa tgtggctatt agtagcttct
     1621 ccaatctttt ttgatagcag catgtgcttt ttctgccgta ttttattgag aataatagtt
     1681 gaccagtcta ggcgattttg ctagaataga gaggtcgcaa gacagactaa ctttttcttg
     1741 gttttaggag tgccaaccct aaaactcgga ttaagcaaaa aaggagaatt attatggcaa
     1801 tctcaaaaga gaaaaaaaat gaaattattg cacaatatgc acgtcacgaa ggtgacacag
     1861 gctcagttga ggttcaggta gctgtcctta cttgggaaat caaccacttg aacaaccaca
     1921 tcaaggagca caaaaaagac cacgcaactt atcgtggatt gatgaaaaaa atcggacacc
     1981 gtcgtaacct attagcatac ctacgtcgta cagatgttaa ccgttaccgc gagttaatcc
     2041 aatcacttgg acttcgtcgt taattggctt gacagaggtc attttagaga taaccaagtt
     2101 ctattgaaaa aagatctgc
//
LOCUS       DARYUW010000118         2010 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYUW010000118 DARYUW010000000
VERSION     DARYUW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2010
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVW11_001956"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVW11_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1366014.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TVW11_001957"
     CDS             complement(664..1245)
                     /locus_tag="TVW11_001957"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1366015.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TVW11_001958"
     CDS             complement(1473..1658)
                     /locus_tag="TVW11_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1366016.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..>2010)
                     /gene="spel"
                     /locus_tag="TVW11_001959"
     CDS             complement(1780..>2010)
                     /gene="spel"
                     /locus_tag="TVW11_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1366017.1"
                     /translation="FQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNWEFHGSGENEEGA
                     DLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
BASE COUNT          557 a          434 c          337 g          682 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa
//
LOCUS       DARYUW010000119         2010 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYUW010000119 DARYUW010000000
VERSION     DARYUW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2010
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            124..315
                     /locus_tag="TVW11_001960"
     CDS             124..315
                     /locus_tag="TVW11_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1366018.1"
                     /translation="MLTYDEFKQAVDNGYITGDVVMIVRKNGQILDYVLPHESVRAWE
                     VVTVEAVADVLAELYNKEF"
     gene            330..593
                     /locus_tag="TVW11_001961"
     CDS             330..593
                     /locus_tag="TVW11_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1366019.1"
                     /translation="MLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAEL
                     YELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDEAKKLN"
     gene            571..996
                     /locus_tag="TVW11_001962"
     CDS             571..996
                     /locus_tag="TVW11_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1366020.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            953..1243
                     /locus_tag="TVW11_001963"
     CDS             953..1243
                     /locus_tag="TVW11_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1366021.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            1230..1664
                     /locus_tag="TVW11_001964"
     CDS             1230..1664
                     /locus_tag="TVW11_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1366022.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            1642..2004
                     /locus_tag="TVW11_001965"
     CDS             1642..2004
                     /locus_tag="TVW11_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1366023.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
BASE COUNT          614 a          352 c          455 g          589 t
ORIGIN      
        1 gttcgttaat aagttgtgtt tttgtttgca ataaaaatat attttactta attttaaata
       61 aattttaaat ttaattatat tatttgctgt aaagtacgaa taataagata agggaggtaa
      121 tttatgctaa catacgacga gtttaagcag gcagttgata acggttatat cacaggagac
      181 gtggtcatga tcgtgcgtaa aaacggacag attttggatt atgtgttgcc gcatgagtct
      241 gtgagggctt gggaagtggt gacagtcgag gcagtagctg atgttttagc tgaattgtat
      301 aacaaagaat tttagtatct tttattgaaa tgcttctggt tttgttaatc attagtgttt
      361 tgatgctgtt atttgttcca aatttaagta aacaaaagga taaggtgaca gacacaggca
      421 atgctgcggt ggtaaagctg gttgaaaatc aggcagagct ttatgaatta tcacatgggg
      481 aaaagccaag cctgaagcag ctgcaagagg atggaagtat cagtgacaag cagcaaaagg
      541 cttatcagga ttattatgca aagcataaag atgaagctaa gaagctcaat taaagctttt
      601 accctcttag agggtttact gacacttttt ctgattagct ttatgctgct gtacttgtca
      661 ctaccggtat cagatagcta tgctagggtt gaggagcatc tctttttcat gcgctttgaa
      721 caggcttata ggcacctaca gaagctatcg atattacgtc aaaaagagca tgtgctggtc
      781 ttaaagccac attatattaa ggccgaagaa gctattttgc ctctaccaaa gcaggtcaag
      841 ctaaaatcta cccagacctt aaccattgat aaactgggcg gcaaccattc gctggcaaga
      901 gttgtctttg aaaatagaga tcggcagatt acttatcaat tttatttagg gagtggtaat
      961 tatcaaaaaa caagtcaaag cctacatcgc tcttgaaggc ttgatagcga caggacttat
     1021 tcttgttatt gtaacactga tactgtcagc cctgcgttat agccaacagg agctgtcggc
     1081 ctgtcgccaa aagcaagagc tgttgaatac agctgtgatg gctatgcaga caaaacaaag
     1141 ggcattaagc cttaatggtt gtcatattaa gctattatca catcagaagg gtatcgctat
     1201 tgttgaaaaa gaccaaacga ttattaggat tgaaagacag taggctaaag gctttcacct
     1261 tgatagagtg ccttattgcc ttgcttgtca tctcaggctc tttattagtt tatcaggcct
     1321 taaccaagag ccttatggca aatgagaggt atctagcagc aaatgatcag aacaactggc
     1381 ttttgttttc ccagcaattg cgagcagagc tttcaggtac taccctacag ggtgtccgca
     1441 ataataggct atatgttgaa aaggacaaga aggctttgtc ctttggacag gtcaagggcc
     1501 atgattttag aaaagcagct agcaatggtc aaggctatca gcccatgctg tttggcttgt
     1561 caagtagcca aataacagca gtaggtcagc aggtgaccat caagctgaaa tggcaaagcg
     1621 gcttagaaag gacctttatt tatgcatttc aagagaaggg ttaaggcagg agtgcttttg
     1681 tatgctttgc tgatggcatc ggtcttttta ttactgttac aggcttatct tagtcatatt
     1741 agccagctac atcaggaata tcaggctcag atggactacg caaaggctca gctaatagca
     1801 gaaatggttt atcaggagca gccttctggc gatggtcaga ttgcctttaa ttgtggtcag
     1861 gttagctata agtcgcataa gcagcgtttt ataattgaga tcaaattacc acatcagcag
     1921 ctatatcaat ttagctatcc tgaagttcag caggcctctc agacttctaa aaagcagtct
     1981 gagcttaagc aatcactccc ataactaagg
//
LOCUS       DARYUW010000120         1959 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYUW010000120 DARYUW010000000
VERSION     DARYUW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1959
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..583
                     /locus_tag="TVW11_001966"
     CDS             <1..583
                     /locus_tag="TVW11_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1366024.1"
                     /translation="NKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLIAL
                     FTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRAIT
                     RYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSPAI
                     LIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
     gene            585..1256
                     /locus_tag="TVW11_001967"
     CDS             585..1256
                     /locus_tag="TVW11_001967"
                     /inference="COORDINATES: protein motif:HMM:NF014420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1366025.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIF
                     ICVRY"
     gene            1270..>1959
                     /locus_tag="TVW11_001968"
     CDS             1270..>1959
                     /locus_tag="TVW11_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1366026.1"
                     /translation="MVELKNISYSYSKENQILQDINIKIQDGECILLCGRSGCGKTTI
                     GRIINNLIPRFFERGVMSGDVYINNENTKDFEMHELANLIGTVFQNPKAQFFHTNSDA
                     EIVFGLENNGMKPEKIRRRYKEVVDELNIHDLTNRDMFSISGGQKQIIAFASIYAMNP
                     KVYVLDEPTANIDKKTIIKIGKIIEKLKKRGHTVIICEHRLYFLKDLVDRVFYVDQGE
                     IKRTFSGDEFFR"
BASE COUNT          698 a          211 c          361 g          689 t
ORIGIN      
        1 caataagtta aaaggaaaag atttaataac aataggcatt tatacagcaa tttattttgt
       61 aataaatttt gcatttatgc tagctggaat gataccagtt atgtggatta tgatgccttc
      121 actgatagct ttatttacag gggtgccata catgatgatt tgcaacaaag ttcaaaaagc
      181 tggtgctatt ttaatcatgg gaacagttac agttttgata tattatgcaa caggacaatt
      241 tacaacagtt attcttgcaa cttttgcagt aggttgtata ttagctgaaa ttattagagc
      301 aattactaga tatacaagtt ttatagggaa tactttatca tttgcactat tttcaattgg
      361 aatgatagga tcgcctcttc ctatttggtt gtttaaagaa tcattttttg ctcatatatc
      421 agaggttggt atgtcgcagg attacataaa tgccttggaa aagtttactt cgccagcgat
      481 tttgatagga gttattattt tgacttttat ttgttcgtta gttggggctt tgattgcgaa
      541 aagaatgatg aataaacatt ttaaaaaagc gggaattata taaaatgcgt gaatatagat
      601 taaaaataga tccgagagca gggatttccc tgctttttat cttaaacttt acgatattta
      661 atgtatccac agtttatgca ttatttgtgc tattaatttg gaactgtgtt tatgcaatgt
      721 gtaatggata ttgtaggata gcaatcaaat tcatttttac ttattggttg ctttatttga
      781 tagaattttt ggttttaccg aaactaccaa gtttaattgc tatttccttt gctattctat
      841 taacttatat tttaaagatg ttaccagtag cattgtttgg atatgttttt gttaaaacta
      901 caagtttgta tgagttaatt acggcactta gaaaaattca ttttccagaa agtataataa
      961 cgggattatc aataactctt agatattttc cggcattaag agaagatttt cataaaacat
     1021 atgatgctat gaaactaaaa aatatgtctg ttttagaaaa aataagtgga ctgataatta
     1081 ctacaatgac aagagccaca ttaaatatag aagaattatc tcaggcagca agtgtaagag
     1141 gcatagataa tcctgtaaaa aaattttctg cggctgaaat aaattttaag acaagtgatg
     1201 cggtagtgtt tatagtgtct tctgttgtct atatttttat atgtgttagg tattgactgg
     1261 aggatagata tggttgaatt aaaaaatatt tcatattcat attcaaaaga aaatcaaata
     1321 ttacaagata taaatatcaa aatacaggat ggagaatgta ttttgttatg tggaagaagt
     1381 gggtgtggaa agacaacaat aggtaggatt ataaataatt taattcctcg tttttttgaa
     1441 agaggagtta tgtcaggtga tgtttatata aataatgaaa atactaaaga ttttgaaatg
     1501 cacgagctag ctaatttaat tggaaccgtt tttcaaaatc ctaaggcaca gttttttcat
     1561 acaaattcgg atgcagaaat tgtatttggt ttagaaaata acgggatgaa accggaaaaa
     1621 ataagaagaa gatataagga agttgtagat gaattaaata tccatgactt gacaaatagg
     1681 gatatgtttt cgatttcggg tggacaaaaa caaataattg catttgcttc tatttatgca
     1741 atgaatccta aggtgtatgt tttagatgaa ccaacagcaa atattgataa aaaaacaatt
     1801 ataaaaatag gaaaaatcat agaaaagcta aagaaaagag gacatacagt aattatatgt
     1861 gaacatagac tttatttttt aaaggatttg gttgatagag tattttatgt tgatcaagga
     1921 gaaattaaaa gaactttttc aggggatgag ttttttaga
//
LOCUS       DARYUW010000121         1955 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYUW010000121 DARYUW010000000
VERSION     DARYUW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1955
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..926
                     /locus_tag="TVW11_001969"
     CDS             <1..926
                     /locus_tag="TVW11_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1366027.1"
                     /translation="SDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIG
                     RLRVLLDEKNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEI
                     TEILSTLVDRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKG
                     VGEFVLNGVADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAI
                     FLFGNKEAEDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISA
                     IEQANKQCDGDIDMSVKNIVQAVKILNKEEF"
     gene            927..1424
                     /locus_tag="TVW11_001970"
     CDS             927..1424
                     /locus_tag="TVW11_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1366028.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     RTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1448..1846)
                     /locus_tag="TVW11_001971"
                     /pseudo
     CDS             complement(1448..1846)
                     /locus_tag="TVW11_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          718 a          226 c          368 g          643 t
ORIGIN      
        1 gaagtgatta tgaagagttt ggatataaca aaagaaaatt atttagagag gttttagaag
       61 gagatttgct tactaaaaca tttctatttt tgggatttag ttttgaagat ccaaatttta
      121 actatgtaat tggaaggtta agggtcttac tcgatgaaaa aaatacaaga aaacattatt
      181 gtattatgaa aagagtccaa gatgctgatg aggattatga atacaaaaaa gcaagacagg
      241 agctacaaat tgaagaccta aatagatatg gtatttttac atatttagta aataaatatg
      301 atgaaatcac cgaaatattg agcactcttg tcgatagatt tagaaggaaa acaatattta
      361 tatctggtag tgcgtactcc tattcggctt attctcagaa aactggcgaa aattttattc
      421 ataaactatc ttttgaacta tcaaaaaatg gttatcatat tgtgaatgga tatggtaaag
      481 gagtcggtga atttgtatta aatggagttg cagattattg tttgactcac aagtccaaaa
      541 taaatgattt tttaacactt atgccttttc ctcaaaatag ttcattaggt attgatttag
      601 ataagctata taaagaaaat agagagcaga tgattgaaag ttgtggtata gctatatttc
      661 tttttggtaa taaggaggca gaagatattg caagcggagt tatggacgaa tatgagttat
      721 caaaaaagca tggattagta tgtttgccta ttgaatatac tggcggtgca tctaaagaaa
      781 tatatgatca aacaactcaa gaaatttcag ataaaaatac aataagtgca attgaacagg
      841 caaataaaca atgcgatggc gatattgata tgtctgttaa aaacatagtt caagcagtta
      901 aaatattaaa taaggaggaa ttttaaatgg caaaaagaca ggtatttttt agctttcatt
      961 acgacaatga taattggagg gcaggacagg ttcgcaatat ggggaaagta gacagtagtt
     1021 ctaccttttc tgataatgac tgggaggaag taaaagaaag aactgaaagt aaaattaaag
     1081 aatggattga tgaacagtta aataagcgtt catgtttggt tgttttgatt ggagaaaaaa
     1141 cagcgaacag aaaatggata aattatgaaa taagaaaagc atatgagtta aataaaggta
     1201 ttgtgggaat ttatattcac aagttggaga attcactggg agagcaagat gataagggta
     1261 ataatccttt tgattattta acattagaag gtgaaaaact ttcaaagtat gttaaatgtt
     1321 ttgactccaa ctattcatca agtaaatatg tttatagcga tattaaagat aatattgaag
     1381 gtttaattga gtatggaata aaccataaac catcaacttg gtaataaatg atgatggaga
     1441 gaaaaaatta tctctccatc tccttaccca tgtaaattcc ataatttttt cgtatcttgt
     1501 aaagttcgtc cataatagat tttgaggaag aatactcttg cataagggta ttcttttttt
     1561 cttgcaattt atcaagtcta tctaaaatac ccttagaatt tggcaacttg gaatatgatt
     1621 ttttaagctc tgaaagggca ttttcatata aggtaatctg agctttgtac tcttcaaaaa
     1681 atgccttgtc agatggactt gccttatatt ctttgtagta ttgcctgtat tttttaacag
     1741 tgtgaacttg ctccatagtg gcagaaagct cctgcatttc cttatcaata gccttgatct
     1801 tatcctgtaa attttgcctt tcatcggctg cttttatgat atatttcgat tatattcgaa
     1861 aacaatattg gaaaatatat ttttatcgtg tataatataa tcaaagctaa agagaggtga
     1921 atgatatgga atatattgaa cgacccaagt attta
//
LOCUS       DARYUW010000122         1952 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYUW010000122 DARYUW010000000
VERSION     DARYUW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1952
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..150
                     /locus_tag="TVW11_001972"
     CDS             <1..150
                     /locus_tag="TVW11_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HEL1366029.1"
                     /translation="IKNLSDKYMLLEQEKTTLMGEYSSQNSMLRKLQQAKKNTDLYLD
                     NSLEK"
     gene            complement(260..745)
                     /locus_tag="TVW11_001973"
     CDS             complement(260..745)
                     /locus_tag="TVW11_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1366030.1"
                     /translation="MIGLVILFIALIILYLGVILFAGATFVKISLFALDKLVVFIASW
                     YYTHHYFSVKFSSGYAIYFWDILAAILVVIIYSILFQFIHKKFRVLGKILNLAISFFS
                     SMIVYCLLVNGFITTEKSYFLPLLNNSFMNQVVNYIIIAIISLVVWKRREDYLVETHD
                     K"
     gene            complement(903..1862)
                     /locus_tag="TVW11_001974"
     CDS             complement(903..1862)
                     /locus_tag="TVW11_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1366031.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT          615 a          375 c          213 g          749 t
ORIGIN      
        1 attaaaaatt tatctgataa atatatgctt ttagaacaag aaaaaactac acttatggga
       61 gaatattcct ctcaaaactc tatgcttcgc aagctgcaac aagcaaagaa aaatacagat
      121 ttataccttg ataacagcct tgaaaaataa aaaaaagaag gagattatcc ctacccatat
      181 ttcaggtaag aataatctcc ttacttgctc tcaaattgat aaaagtatat tttctacaat
      241 atttcacaat aatattttct tatttgtcgt gtgtttctac aagatagtcc tctcttcttt
      301 tccacacaac caaagaaata atagcgatta taatataatt gaccacttga ttcataaagc
      361 tgttgtttaa aagtggcaga aaataggatt tttcagttgt aataaatcca ttcaccagga
      421 ggcaatatac aatcatagag ctaaaaaatg aaatagctaa atttaagatt ttccctaaca
      481 ctctaaattt tttgtgtatg aactgaaata gaatagaata tattattact accaatattg
      541 ctgccagaat atcccaaaaa tatatagcat atccggatga gaatttcact gaaaagtagt
      601 ggtgggtata gtaccagctt gctataaata ccacaagttt atccagtgca aacaggctaa
      661 tttttacaaa tgttgctcct gcaaatagaa tgactcccaa atatagtata attaaggcta
      721 taaaaagaat aaccaatcca atcatatcat tcacctctct atcaaaataa tcttcttttt
      781 cttataatat aacgctcctg ttatagttta tcaaaccttt atttttccat ttctaataaa
      841 aaaacaaaga aaaatagtgg ataaacagcc ctatcagcta tttacccact atttttataa
      901 ttttatctct ctatattttt atcttttttg acactgacct gttcctttga tttttcgcct
      961 gccttttcct tatactcttt taacttgcca agtgctgacg gtttctttac atcctttgca
     1021 ttttgatttg ttttgctctg ttctttggct tttaacagct ttgcagaata aactttaaga
     1081 gatgtatatt cctttccgtc ctttccctga ctgatttttt cttttccgaa tacatgaaca
     1141 aaatctcctt ttttcaaatt ttctacacta cttaccttat cgttataggc taaacagttg
     1201 gtatatttta catttccctc cttgtcattt tcagcaactg caaaacttgc aacagtaaaa
     1261 tctctaccat ctttcgatgt caaattttta atgtctatat ctgaagcaat attgccattg
     1321 atatttacag tatttgcttt ttccttattt tcatttgact tctcactcgt agtattattg
     1381 tcctccttta cattttcctc atcggataaa acactattct tatcctgtat ttcgctttct
     1441 aaatcaggtg cttcaatctc attttcatct atataatgat aaaatttttc atcaaccaaa
     1501 cccataattt tatcattcat ataattatca taagcagcat caagagtatc ctcattttct
     1561 attcctgttt caagagacag aattcctttg acaaaatcgc tatgattata ctctgctaaa
     1621 aaagataagg tctctttcat cgtttcaaaa ttattgtttt gtatatcgga aatgcttttt
     1681 aaatcatttg catatcgccc attatcccat tcaaattttc cgctttcctt gttttcttta
     1741 atccctgttg caagtacaaa ctgagtacct gaaaacagta ccgcctgatt atctttcaca
     1801 tccaaaactg ttgtgttttc acttaatgct gtttttacaa tatcgccttt ttctaatttc
     1861 atatttttta cctcctgtac ttttacttgt atgttttctt ctaattcttt atcaataata
     1921 tttttaatac tttcttttat cgcttctaaa ta
//
LOCUS       DARYUW010000123         1847 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYUW010000123 DARYUW010000000
VERSION     DARYUW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(207..1721)
                     /locus_tag="TVW11_001975"
     CDS             complement(207..1721)
                     /locus_tag="TVW11_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1366032.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          643 a          377 c          299 g          528 t
ORIGIN      
        1 aaatccactt gaaaggctta tcacaagtgg atttttcaga aatattgtac caaataggca
       61 cgagctattg attgctgcta tttagcatag gtgttatcac gatcagcagt aagccaatca
      121 aaacaggtat cgctaaagca aatcctcaca aaaaatggtc caaagaaaaa cctagcagcc
      181 ttataccact tgcttagcaa aaaaacttac tctaccctat ctccaatcaa gagctgctct
      241 aaaagctgct cgtaatgctt acgatgaaag ttcagaattg attttaccac tgtttttccc
      301 tgctccttaa tgtaatccat gctcatacca attaagacgc tcttatctgg aaatacctgc
      361 tgctcctcaa gaaaaggcaa aatattatca ctcgtaatca caaaatcagg agcctgctca
      421 taattttcca gactatctgt tagcatgttg atacgagtaa tattaacctt ataagaagga
      481 atacttgaga taacaaagta agacaagaca tcacctaatg ctctcttgtt ttcaacgatg
      541 atgacctcta caggcggcaa ggacagctca agcatctgct ccaaatgaag gcacataaaa
      601 tgcaggtgcc ctggtgagag cgtttctgac tggtagctaa ccatcagcca gtccttgatt
      661 tgctcctcaa ccttttctag cagcagctga ctgccttgat acctctttga atagtaatcc
      721 tgaaagctaa tcaaatcatg caattgaaag agacatcttc tgaaaaaggg aagcaaaaaa
      781 tacatctgat cccttaaatg aagctgacga ccaaacaaca tttccaagcg attaacaagc
      841 tccttataca gcggatcttc ttctaagata ttgtagacaa gacgtaattg cttgtcattc
      901 caataatgca taagaaaaga actatcaact gtaagataaa ccaagtaaag ataatctaag
      961 tcaccagaat taaacacaac ctgagtacgt gtctcaattt cttgcttagc atagcaactg
     1021 atttgctcaa aaatagataa ttcttttaaa cgatcaaata aagtaagctg tggtaaggat
     1081 acatcataat tctgcctctt ccaagacagc atgagtaaaa tatcaaaaag ataaaatttc
     1141 ttgtccaaga aaacagtggg ctttaaccgc gtaggggtta aaaaaataaa ggcatgaata
     1201 atttccatat ccttaggtgt catctcataa acagcaaacc catactcctt atgaagcatg
     1261 gcaattaagt agcgaatccg gtactcatcc cctataaccc ggtaatcatc gatatccaaa
     1321 tgaatggatt gcaggtagcc ctttagctta ttgacaagat gataggcctt tgatttggaa
     1381 ataaactgtc ttctgatgaa agttgtcaga cactttgtcc tgtaattatc cgtcaacaga
     1441 aacttcaaca ttttaagcgt atcagatgat gcataaatac tgtgaaaata cttctccttg
     1501 ttattaggat caaactcaca ggtaatgcct gacttcaata cagtaataga caggtctttg
     1561 tcaaatagtg cattaatctg attaaggtat tccttagcct ttcgaggggt tattgacgtc
     1621 tgcgagcaca atgaatcaag tgtaatctct ttttctgtca ataagacagc caatattagt
     1681 tttcgctcaa caatatctct ttctaaatag taatctaaca aaataatctc tctccttatt
     1741 agtttgtatg accatataca ttttagttga taggatttaa aagtcaacta aaaaaaatac
     1801 acaaaaaata acgactgctt cctttcaagg atcatctgaa aatgata
//
LOCUS       DARYUW010000124         1827 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYUW010000124 DARYUW010000000
VERSION     DARYUW010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1827
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            388..846
                     /locus_tag="TVW11_001976"
     CDS             388..846
                     /locus_tag="TVW11_001976"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1366033.1"
                     /translation="MKETVVLAKKEYILENEIYTPIVKESPFERQGGTYRLEKMEDGA
                     EVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLMDHLIDIQEQVE
                     DFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQIIWV"
     gene            732..>1827
                     /locus_tag="TVW11_001977"
     CDS             732..>1827
                     /locus_tag="TVW11_001977"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1366034.1"
                     /translation="MENDHRNAGSGLSEIHRTEEELGYDTNKNGYGTDHLGIDEYRKE
                     NIQKIEQNHVENEEKEVERTSFSFAQNVGVQGRFELPMQQEEIGAVLIHGGNEDNLHL
                     KVLAEYSKEKSMEELADFLQKTFQGGNGYELNGNKVCAWYEMDGIHLSNDVSSRENPM
                     QILPWKDAAIRIGELIDYGKYSTNVEVAEAFSFERAELSEKLWFLKGDLSDEVKNQFL
                     PILNEKQRNGYPEKTEYLTKKLEDKEFRVNLKEEYIEFFKAYKENSNVLRFHNHDLDD
                     ISKRLDDLELPRKEFTSTLIELPAIQGFITEDEIDRYLSSGSNVSGGKERIYNFFREA
                     HTTEERANFLKDEYGTGGQTHALSRARGSSE"
BASE COUNT          741 a          208 c          414 g          464 t
ORIGIN      
        1 ttaattcttt aagtgatgaa actttaaagg aaaataagaa agtacaaatt cttcattttt
       61 tggaagaatc tgcaaaagta tcggtatatg agagaatggg agttgcattt tccggtgata
      121 tagaaaaatt agagatgctt tcaaatgttt caagtatgca ggatattgac agattacttt
      181 tctttacttc aaacaatgta aaaagaatac ttatggatat aagtagagaa atttcaaaag
      241 tggaagaaag agaaaaaatt tcagaaattc aaaaaaggga gcagacaaat agtattgcgg
      301 agcgttatac taatgttaca gatgaaatta acggaaatac cgaaattata gaaaatgaaa
      361 aagaaagaaa tgaaggaggt ttggaagatg aaagaaaccg tagtattggc gaagaaggag
      421 tacatcctag aaaacgagat ttatacaccg atcgtaaaag agagtccatt cgagagacag
      481 ggagggactt acagattgga gaaaatggag gatggagcgg aagtattagt tccgaatatg
      541 aaaatgccgg agaaaataaa cgcaagcaaa ctgaaccgat ttggcaagga gagactgaaa
      601 tatctcaaag aggagaaaca agaggaatat cagattatgc tgatggaaga aactttaatg
      661 gatcatttga tagatattca ggaacaagtg gaggatttcc tgaatataga agagccgagg
      721 atgaaagaag cttggaaaat gaccacagaa atgcaggatc aggactttct gaaatacaca
      781 ggactgaaga agaacttgga tatgacacta acaaaaatgg ctatggaaca gatcatttgg
      841 gtatagatga gtatcgtaaa gaaaatatac agaagataga acaaaatcat gtagaaaatg
      901 aggaaaaaga agtcgagagg acttcttttt cttttgctca aaatgtagga gttcaaggaa
      961 gatttgaatt accaatgcag caagaagaga ttggtgctgt tttaattcat ggaggaaatg
     1021 aggataattt acatttaaag gttttagccg aatattctaa agaaaaaagc atggaagaat
     1081 tagctgattt tcttcaaaaa acttttcaag gaggaaatgg atatgaacta aatggaaata
     1141 aggtttgtgc ttggtatgaa atggacggga tacatttatc caatgatgtt tcctcaagag
     1201 aaaatcctat gcagatttta ccatggaaag atgcagcaat acgcatagga gaattgattg
     1261 attatggaaa atacagtaca aatgtggagg tagcagaagc cttttctttt gaaagagcag
     1321 aactttctga aaagctgtgg tttttaaaag gagatctaag tgatgaggta aaaaatcagt
     1381 ttttgccaat tctaaatgaa aaacaaagaa acggatatcc tgaaaaaaca gagtatctta
     1441 caaaaaaatt ggaagataaa gagtttagag tgaacttaaa agaggagtat atagagtttt
     1501 ttaaggcgta taaggagaac tcgaatgttt taagatttca taatcatgat ttagatgata
     1561 tatcaaaacg attagatgat ttggaactgc caagaaaaga atttacctca acacttatag
     1621 aattaccagc aatacaggga tttatcacag aagatgaaat tgatagatat ttaagcagcg
     1681 gtagcaatgt atccggcgga aaagaaagaa tatataactt ttttagggaa gcccatacta
     1741 ccgaagaacg agcaaatttt ttaaaagacg agtacggaac aggaggacag actcatgctt
     1801 tatcaagggc aagaggaagt agtgagt
//
LOCUS       DARYUW010000125         1765 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYUW010000125 DARYUW010000000
VERSION     DARYUW010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            95..361
                     /locus_tag="TVW11_001978"
     CDS             95..361
                     /locus_tag="TVW11_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEL1366035.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            489..1628
                     /locus_tag="TVW11_001979"
     CDS             489..1628
                     /locus_tag="TVW11_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1366036.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
BASE COUNT          683 a          334 c          308 g          440 t
ORIGIN      
        1 ctcgtttcat ggaaaaatat aagttaaaaa caattaccga tgaaaaaatg gtaattgatg
       61 aatattatac tttaataggt taaaggagat tatcatggga tttttggaca atgtaaaaga
      121 agctagtact gtttcgactg cttctggcga aaattatgaa tatgttgtgc tacaagttac
      181 actaaaagaa aagcttatag gaacaggctc aggaaattta actgaacttg aaaatgttat
      241 taataagcaa gcaaaaaaag gatatcgcct acacactatt accacatcaa atggtggcag
      301 taaaggattt ggtggcggag atagaataca agctacaatg gtatttgaga aaatcaagta
      361 aaataaaaaa agccctacgc tcaaattttg gtcggtgcga gcgtgaggca aatctagtat
      421 agtaaaaacc tgcttcgcag taggtctctt tactatacct attttaacag aaaatgaggt
      481 aaaaaacaat gtggtcagaa aaacacaaaa gcggaaaagt aaattttgta gaacggtaca
      541 aacacccgta tactggcaag tggtgcagag cttctgtcct tatggaaaaa gacacgccac
      601 gaatacgaaa agaagcccaa aaatatcttg acgaaaaaat atctaaaatc ttaacaagtc
      661 ttaccacaac cgatgcctac ctactagatg tcatgaacga atggtgggaa catcatcaga
      721 aatcactcaa atcaacttct gtccgctctc ttgattttag aataagagaa ttgcgaaact
      781 taattgatcc agaagtgatg attgccaaga taaccacgaa atacctgcaa agtattatcg
      841 acaaaatacc aggtagttat gacaaacgta aacgagcacg gcagctgctc aaacaaacct
      901 tcgactacgc tatcgcttta gagtatgtct caatcaatcc agttattagt acccaactcg
      961 caaaacctgt taagaccatc aaagactttg aagacgttgc ccagaagttt ttagaaaaag
     1021 atgaactcaa aaggctatta gatgaaatgt atagacgtaa aggatcgatt aaaatggctt
     1081 atctggcaga atttatgagc ttaaatggct gccgcattgg agaagctcta gctatacagc
     1141 cagacaatat caaaaatgat atcattgaaa tccacggaac tcttgactac acctcaaatg
     1201 gctatagaaa cgctatcaaa accaccccta aaacaaattc cagttggcgt gaaacattga
     1261 taaccaaacg tgaaaaagaa attattcagg atatactgaa aattaatgct cttgaaaaaa
     1321 atactaatcc taattacaag gacatgggct acatcttcat ttccagaaat ggtgttccta
     1381 ttcaagacaa cgccctcaac acctctatca gagcggcaaa taagagacta gaaaaaccga
     1441 ttcaaaaaga actcaccagc cacatcttcc gtcataccct ggtgagtcgc cttgcagaaa
     1501 acaaagtgcc cttaaaaact atcatggata gagttggaca tgctgactcg aaaactactc
     1561 aacaaatcta tacccacgtc acgaaaagca tgaaaaatga agtcgtcgac atcttaaatc
     1621 ggctataata tgccccaaaa atgccccaaa acacaagaaa aaaccttgac atcttcaaca
     1681 aacgttgata tgacaaggtt ttttaatgtt ttatttaatc acttattgat ttatataaag
     1741 atcaatcaag caatgaatta gatat
//
LOCUS       DARYUW010000126         1698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYUW010000126 DARYUW010000000
VERSION     DARYUW010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..230
                     /locus_tag="TVW11_001980"
     CDS             <1..230
                     /locus_tag="TVW11_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366037.1"
                     /translation="LGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLL
                     CLTIVGIPFARQSLKLAKISLFPFGAIIYDI"
     gene            249..893
                     /locus_tag="TVW11_001981"
     CDS             249..893
                     /locus_tag="TVW11_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1366038.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(1324..1491)
                     /locus_tag="TVW11_001982"
                     /pseudo
     CDS             complement(1324..1491)
                     /locus_tag="TVW11_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          496 a          351 c          293 g          558 t
ORIGIN      
        1 ctttgggtct ttttcctttt ggaaaagcca tcgaaattgg ccaaggagca ggcagcctgc
       61 tgctcaatat catctggatt gtctgctgtg gctggagctt agcgatcatg catttgactt
      121 ctgcccttct cttgtgcctc acgattgttg gcattccatt tgcccggcaa tctctaaaat
      181 tggccaagat tagcctcttt ccttttggag ccatcattta tgacatttaa ttaggaagca
      241 aaagacttat gaaattgtat tttgtcagac atggtaaaac cttgtggaac ctagagggcc
      301 gttttcaggg agctaacgga gattcgccct tgcttgaaag ctctaaggac gatttgcgcc
      361 agctagcaag agagctgtgg gacatttctt ttgatgcgat ctactccagc gacctaaaaa
      421 gagctgttga tactgctcgc attattgtgg acgaagctaa ctgcaagact gatattagtt
      481 ataccaagca gctgagagaa tggaacctag gcaccctgga aggaaccaaa atagcaactg
      541 tatccgccat ctaccccagt cagatgtcag ccttttatca caatttagcc aaattcaagc
      601 ccagtcaatt taaggctgaa tccctttatg aaagcacaca aaggctttat cagctcatta
      661 aaagtttgga agataaggcc tatcagcagg ttttaatggt aggacatggc gcccatttga
      721 cagcttctat tcgtgctctt ttaggctttg agccaggtat gcttcgggca cagggaggac
      781 tggataatgc cagcctaacc gttatagaaa ccttggattt caaacacttt cattgtctaa
      841 ggtggaatga tacatcattt ttacaaaaaa agactactag attaacaccc tagtagctct
      901 taagcacaaa gctccaagac agctaaactg tactccattg gttagagaac acatctcatt
      961 ttttgaggga cgctttatta gctgtaggaa gttatgaaaa gctaaataca cgagaggact
     1021 aaattggaca agctcaaaag tttgacaatg tatttcaaaa aaggattgaa ttctgtatcg
     1081 aacaggactc agtccttttt atcatttatc aagccgacca aggctttcaa ccacgacaaa
     1141 cgcgcaaaac agttatttcc tgatgatagt agagactaca gcagatattt tcaatgattt
     1201 tcttgtagta acatctatac aaaacaatac agctcattga aatataggaa cattaaaatt
     1261 cagaaagatt tcttttcttg ctaaaaatct ttcatccatt tcaaactggt tttcatttgt
     1321 cctctccttt ttcagttctg ctttttctcc ataagctgca cagttgatgt actccttgcc
     1381 tttaccgtac ttctttacaa atgtaaaatt tacaacttat acttcttctc cttctctttc
     1441 aaaacttgag taaattgatt ctgctactaa atttgcgtta atattaatca ttttttatcc
     1501 ataatttttc tcctttttta atttaaaatt cccattaaaa aagcgactgg actttttcca
     1561 atcgctgata cttctactat tttattttta tttcggtaga acttctaatc cttatcatct
     1621 atatcctcct ttttaaacac aaaaaagacg gtagattttt tctttttcca ttgtctctta
     1681 taacttatat ttaatttt
//
LOCUS       DARYUW010000127         1612 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYUW010000127 DARYUW010000000
VERSION     DARYUW010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1612
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..409
                     /locus_tag="TVW11_001983"
     CDS             <1..409
                     /locus_tag="TVW11_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366039.1"
                     /translation="AEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLNLTDKLKD
                     SLGFDETFLNKKLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTGNLDPARSKAI
                     LDYILSIKNAIIIVITHNQDIKTLEQFDEVICL"
     gene            572..1612
                     /locus_tag="TVW11_001984"
                     /pseudo
     CDS             572..1612
                     /locus_tag="TVW11_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          608 a          172 c          298 g          534 t
ORIGIN      
        1 tgctgaaatt aactcagaaa gtttgtataa gaagattgcg tttgttcaaa aaaatgattt
       61 tcttgtggaa ggtaatgttt cagacaatat taaattagat gggagtttga atctaacaga
      121 caagctcaaa gatagtttag gatttgatga aacattttta aacaaaaaat tatttagagt
      181 tcagtcttta atctcagaag gagaaaaaca aagaattgat ttagcaagat ttttaaaccg
      241 tagatattct atttatattt ttgatgaacc aactggtaat cttgatccag ctagatctaa
      301 agccatattg gattatattt tatcaataaa gaatgcaatc atcattgtga ttactcacaa
      361 ccaagatata aaaacgttag aacaattcga tgaagtcatt tgtttgtaaa tgaaaggggg
      421 tgatgaacat gattatggaa gattttgaag ttttagaact agagtttgtc gaagttcgaa
      481 atgaacaaac cacaaattgg tattttgttt aatcacaaag gcatgcaatg agaatttgca
      541 tgcctttgta aaatatagaa aggacaataa aatgaataat ttttttccaa aatggaatca
      601 ggataggatt gtatattcat ggcaaaatga taaattaagg ataggagctg atgataatga
      661 tgttctagaa atcaaaggaa actcaatttt ttggtcagat tttatttctt gttgtgacgg
      721 gaataatagt atcaaagaca ttcaaaaact attgaatata aaatataata tttcagaaga
      781 aataattaca gagtatttag ataaattctc aaatcgaaat ttattggaaa tattggataa
      841 tccaataaat caattacagg attataaatc aattgagtcg ttagaaacat attatgctag
      901 tgaaggaatt ggtgggatta aactattaaa aatgttaggg aatctaaaga tttctattct
      961 gggatgtggt ggtggtggat ctcatattgc attacaatta gctcaattag gagtgggaag
     1021 aattcatttg gtggattacg atattgttga agaaaacaat atcaacagac aatccatgtt
     1081 cacatttaac gatgtcggaa attacaaagt tgattgtgta gccaaaaata ttcagcaaag
     1141 aaattctaaa tgtttggtta ccaaaagcac ttctaaaatg attaatgtac ctgatgtaaa
     1201 aaaaagaaat atctgaaagc gattgggtat tctgttgcat ggatgaacct ccttatatag
     1261 cacagaggat tgtaaataga gcatgttatt tattaaaaat tccaagtata tactgtttta
     1321 gccaacgtag tgcggggaaa cttttgtttt gtaatcctaa tattgaagat tctggctgta
     1381 ttgattgttt gttatctgaa caagataatg aaaactttca aaagctggtg acaacgttca
     1441 ctacctataa taggaaattg gtaactgcaa atatcttacc aaatatttta ttattgacat
     1501 cgtgggtggt taaacgatgg ttagattgtg taacagataa aaatagtaat gtatggaata
     1561 tgttgttgag atttgatttt tataaatata tggaagaaaa atttcaatat tt
//
LOCUS       DARYUW010000128         1608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYUW010000128 DARYUW010000000
VERSION     DARYUW010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TVW11_001985"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TVW11_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1366040.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TVW11_001986"
     CDS             691..1080
                     /locus_tag="TVW11_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1366041.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TVW11_001987"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TVW11_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1366042.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          483 a          289 c          375 g          461 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYUW010000129         1590 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYUW010000129 DARYUW010000000
VERSION     DARYUW010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1590
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(283..576)
                     /locus_tag="TVW11_001988"
     CDS             complement(283..576)
                     /locus_tag="TVW11_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1366043.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            complement(606..827)
                     /locus_tag="TVW11_001989"
     CDS             complement(606..827)
                     /locus_tag="TVW11_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1366044.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1042..1512
                     /locus_tag="TVW11_001990"
                     /pseudo
     CDS             1042..1512
                     /locus_tag="TVW11_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          517 a          291 c          255 g          527 t
ORIGIN      
        1 catgacaaca acattaaggt aaaaataaat cattatttgt aatgtacttg acaaaatctc
       61 ctttataaga atgattgtaa ctaaaattgg aatcaaaatt gtacttttaa aatatagcca
      121 aaattgtttt gcaatttgag agattgaaag aacttccttt gactgtttat agactaatgt
      181 aaaagttagg agttcaagca aaaaactcca aaaaatgtgt cttattttat gagtgcattg
      241 ccaatctaca actccttcta aatcctgatc tgaaaatatt ttttaacgaa atatattact
      301 taaccagaat ggtatagaaa ttaaacctct atgtttagct ggggttgatg cgatagattg
      361 agcaagaact ataatcgctt ttggtgcctc ataatgattt gtcattagat aggttgaaat
      421 atgtcctgct aacctggtac taactaaata cacaggcttt ttgagtgata attgctggag
      481 actttcttcc aaaagattcc tataagtgac attattttgc acctcttcat cttttagagt
      541 ctgttctatc agctgtacta aatctctttc attcatgatt tcacacctct ctatataaat
      601 taaaattatg gacgacttgc ccaaggtcca tggttaaccc aaccattgac aattatctta
      661 ccaacatatg gtcctgccac actccagtcc ataccacatt ttgcactatt ttttcctgta
      721 ttccaacaat atacaccggt ccctccaggt aattttacaa ctccattttt tccaccctca
      781 actgatttca attgctcttc agtcaacgct gtaaattttg tatccatgac gaatacctcc
      841 tttatatgtg tttttatttt gtccggttgc aagcttgaca gacttagtat aacactttcg
      901 gttaaaattt gttctccatt tcctaaacag tcatcgaaac gtcctaaatg ggaaaaattt
      961 accgcttaag acttaaattc aaccgtttga gataatttga tagatttgtc agattaccat
     1021 ttaggacgtt tcgataacca atatctgcct caacaagctt atatttttag tggatcaatt
     1081 ttagaaaatc ttactctcgg tgcaaaccaa gcgattactc aagaggatat tatcaatgcc
     1141 tgtgatatgg cagaaattag agaagatatt gaacaaatgc ctatgggcta tcagacagaa
     1201 ctatctgatg gggcaggatt ttctggtgga caaaaacaga gaattgcatt agctagagca
     1261 ttattaacca agtctcctat tctaattctc gatgaggcga caagcggact agatgtctta
     1321 acggagaaaa aagtgattga taacctaatg tcaatgaccg agaaaacgat tattttcgtt
     1381 gcccatcgtc ttagtactgc tgaacgtact agccaaattg ttgtacttga taaaggaaaa
     1441 ataatcgaga taggttcgca taacgaatta atgacgcatc aaggcttcta tcatcattta
     1501 tttagtaagt aaggagatat tcatgaatcc aaatctgttt agaagtgctg aattttatca
     1561 gcgacgctat cataattttg cgataattct
//
LOCUS       DARYUW010000130         1589 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYUW010000130 DARYUW010000000
VERSION     DARYUW010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1589
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(171..461)
                     /locus_tag="TVW11_001991"
     CDS             complement(171..461)
                     /locus_tag="TVW11_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366045.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TVW11_001992"
     CDS             complement(442..834)
                     /locus_tag="TVW11_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366046.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..>1589)
                     /locus_tag="TVW11_001993"
     CDS             complement(816..>1589)
                     /locus_tag="TVW11_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366047.1"
                     /translation="ATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAY
                     FGTDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLT
                     VLASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALD
                     HKTVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKL
                     SALATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
BASE COUNT          396 a          396 c          311 g          486 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgc
//
LOCUS       DARYUW010000131         1457 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYUW010000131 DARYUW010000000
VERSION     DARYUW010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(152..1381)
                     /locus_tag="TVW11_001994"
     CDS             complement(152..1381)
                     /locus_tag="TVW11_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1366048.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDK
                     DGNIISLWGKLGGKDPR"
BASE COUNT          405 a          363 c          272 g          417 t
ORIGIN      
        1 tagcaaagcc aaggtatttt ttttcatttt ttctcctaat attttttaaa tttaatcaat
       61 ttacttagca agtatactat atttaaataa taattcaact ataatttaaa aaaaacaaaa
      121 aaccgccctc aatcaagaga gcggttttgt cttatctcgg atctttacct cctaatttac
      181 cccaaagact gataatattc ccgtctttgt cagtaggacc aattgccata taattacgct
      241 tacctgagcc tccgacatag ctaatccagt agtagccatt ggcgtaaccc tcactatcaa
      301 agctaacggt ttggccttgc ttataactat ctactacctc actggttaaa ttcggccagc
      361 ggcggacgtt gatctctgcg gcgtcaagtg taaaagtacc tgattttgat gtctctacga
      421 tcgtgtctga ggtttgcggg tctgtgctga ccgtttgtgc agcaacatct ccctgataag
      481 gaggataaaa ccagccggcc acattagtaa agtcacgagt attaaaacgg gccggacccc
      541 ctacatacaa cgcatctgca ttaccatcaa tattttgctc gatagtctgc atagtgtaac
      601 catctgagtc aacgtacaca agacccgtat gaccataatt gataccacca aaccaagcgt
      661 ccatgacaaa aaatgcccca gctcgtggat ttgcatctgt aggcatgcga tggacttccc
      721 agccctgcgc acttgcgcta tctagtaagt ccgctgcgtt gccccagaga tcgacaccaa
      781 accagtgctt agctgcgtaa caagggacat ctgcacattg cgtgccataa gccccgtcct
      841 tatcaacacc cataccagca ttagccaaat tgatgtaaaa ctcgataacc tctcgacact
      901 gcgaactaat catttgtgac tcctttcttt ttgctagggc ttccgcgtcc catttttgta
      961 ggtcgttttg ctctattagt tggataagca gctctgcata atcacttgca gtggcataac
     1021 cagctgcttt tattgcatga caagcctttt tatagtcggt ctccccgata actgatttgt
     1081 atcgtggatt atccactaaa aactggccat gatcaaggat tgactcgtcc caactgtcat
     1141 aggctctaaa gcggtccacg agatccgtca cgacacctgg ctgatactcc tcttgtgtct
     1201 tggtatcaaa agatttacca gaccatgagc tatctgcctt gataccaaac aatgcgttat
     1261 gtggggcata cttgccccaa ccgctctcta aaatagcttg agcagccgtc agagatggca
     1321 aaatcttatg attgtgccac tctgcgataa ctgcgctttt tatgtcgtct aaaaaggtca
     1381 tctgtcctcc tcacctaaaa acggataaaa gataagagca atcacagata gcggtaaata
     1441 tagtattgcg attgcta
//
LOCUS       DARYUW010000132         1445 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYUW010000132 DARYUW010000000
VERSION     DARYUW010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            49..1200
                     /locus_tag="TVW11_001995"
     CDS             49..1200
                     /locus_tag="TVW11_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1366049.1"
                     /translation="MSKNFKNSLVKIAIAALASFAVITIPTYQHSVISAKTVSVNQTY
                     GEYKDYYTVIGESNIDKSTFPEIYKTTERVYKGQGTSEKRVTVSDVVYNPLDGYKRST
                     GAYGVVTKDMIDMSKGYREKWETNPEPSGWFRFYNRADHEEISEKEYDSRRTKSYKVT
                     NNVPVVLTTLKGKKYNSHLFVRSHLFADSLGGKSIRKNAITGTQMQNVGTRKGGMQYI
                     EKKVLSHITKNPDVYVFYSAIPEYQGTELLARSVLVSALSSDGVINETVRVFNTADGF
                     NIDYQKGGLLSPTADVDTNNTEENVENETETTKDEVESEVDINTVKEDDENISLQNTV
                     YVASNGQSNVYWYSKENMPKNVNLDKVVEMSEQTALARGKHHSTQENIE"
BASE COUNT          565 a          229 c          256 g          395 t
ORIGIN      
        1 atttaaagtg ttatacttaa cctgtaaata aaaaaggagg gcattgatat gtctaaaaat
       61 ttcaaaaact ctctcgtcaa aatagctatt gcagcacttg catcatttgc tgtgataact
      121 ataccaactt atcagcacag cgtaatctca gctaaaacgg tctcggtaaa tcaaacttac
      181 ggtgaatata aagactacta cactgtaatt ggtgagtcaa atattgacaa atcgactttc
      241 cctgaaatat ataagaccac tgagagagtc tataaaggac aaggtacaag cgagaaaaga
      301 gtaacagtct ctgatgtagt ttataaccca ttagatggct ataaacgttc aacaggcgcc
      361 tacggcgttg tcacaaaaga tatgattgac atgtctaaag gatatcgtga aaaatgggaa
      421 accaatcctg aaccaagcgg ttggttcaga ttttataata gagctgatca tgaagaaatt
      481 agtgagaaag aatatgattc aagacgtact aaatcatata aagttacaaa taatgtacct
      541 gtagtgctaa caacattaaa aggtaaaaaa tacaacagtc atttatttgt acgtagccat
      601 ctctttgctg atagtcttgg aggaaagtcc atacggaaaa atgctattac tggaactcaa
      661 atgcaaaatg taggaacacg taaaggtggg atgcaatata ttgagaaaaa agttttaagc
      721 catatcacta aaaatcctga tgtttacgta ttctacagtg ccattcctga atatcagggt
      781 actgaattat tggcaagatc agttttagta tctgctttat cttccgatgg agtaattaat
      841 gaaactgttc gtgttttcaa taccgctgat ggatttaata ttgattacca aaaaggtgga
      901 ctcttatccc ctactgctga cgtagatact aataacaccg aagaaaatgt agaaaatgaa
      961 accgaaacta ctaaagatga ggtcgaaagc gaagttgaca ttaatacagt aaaagaagat
     1021 gatgaaaata tttctttaca gaacactgta tatgtggcaa gcaatgggca atctaatgta
     1081 tattggtaca gcaaggaaaa tatgcccaaa aatgtaaatt tagacaaagt tgtggaaatg
     1141 agtgaacaaa ccgctttggc tagaggtaag caccattcca ctcaagaaaa tatagaataa
     1201 caaatctaac aaaccaacga gaacttgaaa aatagttttt atattctcat tagttatata
     1261 ctagcacacg aaacacaaaa aaccgcccag aaattaatct gggcggttga tttttaatta
     1321 aagaaacagt gactaattac agttataaaa acaagcaata ttattaaaga aaaataaaat
     1381 gaatgcctca taaaaaaatg aattttatac ttgcaaccat tgacacattt cggtgaataa
     1441 caatt
//
LOCUS       DARYUW010000133         1432 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYUW010000133 DARYUW010000000
VERSION     DARYUW010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>1432
                     /locus_tag="TVW11_001996"
     CDS             <1..>1432
                     /locus_tag="TVW11_001996"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366050.1"
                     /translation="VFIEGDKLKYKSTCGMPSEEDIEFLKINKTSIIDILNKNDGASR
                     YSLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPLLDIDRAEKVWNDIILK
                     HDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRDKLKGKSYNADIWPLFD
                     ISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKTIMDNSYDLKEIRTSQL
                     KLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERIQLRIDENTWSKIKSNI
                     SEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYIKSDVVNDFTSTELLEF
                     RMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVERRDAIFPFVFTSALGI
                     KASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRADAFSKELSNSIAEDYS
                     NLLNCFFDLEYFKKTLTEMYDENEMND"
BASE COUNT          552 a          161 c          253 g          466 t
ORIGIN      
        1 agtatttatt gagggagata aattaaaata caaatctact tgtggtatgc cctcggaaga
       61 agatatagaa tttttaaaaa taaataaaac ttctattatt gatatattga ataaaaatga
      121 tggtgcttct agatattcac tagatattga tgaattacct ttaacagaaa ttcaaagtgc
      181 atatttatta ggtagaagaa atcattttga acttggtggt gttgccagtc atgtttatat
      241 ggaagtaata ttacctctat tggatataga tcgagctgaa aaggtttgga atgatataat
      301 actaaagcac gatgcattac attcaatatt tacatcaaac aatactcaga aagtactgaa
      361 ggaatttgct tactataaaa tcgaatgcaa tgagggtgca gatataaaag aaaaaattgc
      421 attaacaagg gataaactta aggggaaaag ttataatgca gatatatggc cactattcga
      481 tataagtgta agtcagttag atgacaatag tttattgcat ttatcatttg attttttgat
      541 tttagattgg gcaagcattt ggattttatt aaaggaattt gaagagtgtt attttgacgg
      601 aaagacgatt atggataatt cttatgatct taaagaaata agaacgagtc aacttaaact
      661 gaaacatagt tctaagtatt tatcggataa agatttctgg gaaagaagaa ttcctttttt
      721 gcctgacgct ccactattac caattaaaaa taaaatagtc aaaaatggtt ttgaaagaat
      781 acaacttaga atagatgaaa atacttggtc gaagataaaa tctaatataa gtgagattgg
      841 tgtcacgcaa acatctttct tggtgacaat attagctctt gttcttaata gatggagttc
      901 taattctgaa tttaccatta atttaacaac tatgaataga ccaaaggagt atataaagag
      961 cgatgttgtt aatgatttta catctacaga acttttagag tttagaatgg aatctctgca
     1021 accattctat gttttattaa aacacataca acagcaaatg attgaagatt tgcaacatga
     1081 aacatttaca ggagtggaag ttactcgtga agttaggaaa aatgtagaaa ggagagatgc
     1141 tatatttcca tttgttttca caagtgcatt aggaataaaa gcttcagaat ataaatatat
     1201 tagtttacaa aaagaaggtt tgagtgaaac tcctcaagta ttaatggatt gtcaagtaat
     1261 ggaggtaaat catgaactaa taattaattt tgacttaaga gcagatgctt tttcaaaaga
     1321 attatcaaat tcaattgcag aagactattc taatctatta aattgctttt ttgatttaga
     1381 atatttcaaa aaaacactga cagaaatgta cgatgaaaat gagatgaatg ac
//
LOCUS       DARYUW010000134         1375 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYUW010000134 DARYUW010000000
VERSION     DARYUW010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..704)
                     /locus_tag="TVW11_001997"
     CDS             complement(<1..704)
                     /locus_tag="TVW11_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1366051.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKLVESTMELIIGLPIVKAF
                     NKGDISLKNFNAAILS"
     gene            complement(709..>1375)
                     /locus_tag="TVW11_001998"
     CDS             complement(709..>1375)
                     /locus_tag="TVW11_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366052.1"
                     /translation="TAIVGPSGSGKSTIIKLISRYWDVCGGEITIGGKNVKDISLNQL
                     NDLIGYVSQNNFLFNESIMENIRMGNPDASDEEVIEVSKICACHDFIMELEEGYNSNV
                     GSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAFIDPDNEEKIQGAINVLTKNKTL
                     IVVAHRLSTIKNADKIVVLKNKTIFDTGTHDELLEKCDLYKNMWLSHIGAKSKSIVSN
                     IGG"
BASE COUNT          470 a          260 c          149 g          496 t
ORIGIN      
        1 ctacttaaaa tagcagcatt aaaattttta agacttatat cacccttgtt aaaagcttta
       61 acaataggaa gtcctattat aagttccatt gtagattcaa ctaatttact ttgtgcatta
      121 agataaaaaa cagaattttt ctcagaatgt ttacgaagta acaataaaca aaaatacgaa
      181 agtactactc cagaaactgc tacaacaccc aattcccaag ataaaaaaga aatactgatt
      241 atcataacaa gtgccattat ataaccgtta ataactatgt ctatcatttt catcgaataa
      301 ttttcaaaaa aagacaaatc tgtggttacg gcagtagtca attctcccgg attattttct
      361 tgaaaaaatc ccaatggtac tctttttaat atatcaccaa tttgtactcg ttcatcagct
      421 gacatctcat aaccaatact atcctgattt acagacttaa aataagcagt tatatatctc
      481 cctaaaacca atccaatcat tatagtagtc actatggcta tttctttatt tccatatgtt
      541 gtactcccat aatagtttcc aagaacgaga ttaaaaacat atattgatag cattattggc
      601 attgcaataa aaacagaatt taagaaagat aatataaacc ctttttttat tctcgtacta
      661 tattttctag accaatttaa tattctgaca gtcgttttaa acattgcact aacctcctat
      721 attagatacg attgatttcg atttggctcc tatatgcgat aaccacatat ttttatataa
      781 atcacatttt tcaagaagtt catcgtgtgt acctgtatca aatatagttt tattttttaa
      841 aaccacaatt ttatctgcgt tttttatagt tgataatcta tgtgctacaa ctattaaagt
      901 cttatttttt gtcaaaacat taatagcacc ttgtattttt tcttcattat ctggatctat
      961 aaatgctgta gcttcatcaa gcaatataat aggagcattt ttcaacatca ttctcgctat
     1021 agaaatcctt tgcctttgtc cacctgaaag cttacttcca agacttccca cattggaatt
     1081 atatccttct tcaagttcca taataaaatc atggcaagcg caaatctttg atacctctat
     1141 aacttcttcg tcacttgcat caggatttcc catccgtata ttttccataa tactttcatt
     1201 aaatagaaag ttattctgcg atacataacc aattaaatca ttaagttgat ttaatgatat
     1261 atctttaaca ttttttccac ctattgtaat ttccccacca caaacatccc aatatcttga
     1321 aataagtttt attattgtgg attttcctga acctgatggt ccaactattg cagta
//
LOCUS       DARYUW010000135         1353 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYUW010000135 DARYUW010000000
VERSION     DARYUW010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..355
                     /locus_tag="TVW11_001999"
     CDS             <1..355
                     /locus_tag="TVW11_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1366053.1"
                     /translation="RNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILEKDIFV
                     LDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIYFLRKK
                     LYELGNFGTSGTEEI"
     gene            355..>1353
                     /locus_tag="TVW11_002000"
     CDS             355..>1353
                     /locus_tag="TVW11_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1366054.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVAS"
BASE COUNT          557 a          194 c          249 g          353 t
ORIGIN      
        1 aagaaataat ggaatatacc ttatgctttc tgatgatgaa cttgaaattt tgaataaaaa
       61 atatgaactg tccggttgta aaagtttaag acagtttatt atgaagtgca tccttgaaaa
      121 agatattttt gtactggata tgaaagtgtt taaggagatg tctacaaata tcggaaggat
      181 tacaggtagc atcaatcaga ttgcaaaaag ggtaaattca actgctgtaa tttacaaaga
      241 tgacatcaat gatttgaaaa agctcttgga aaaacaagga aaagacatct actttcttcg
      301 taaaaagcta tatgaattag ggaattttgg aacaagtggt acggaggaaa tctaatggca
      361 gttacaaaaa ttcatccgat agaaaaaaca ctttatctag cattagacta tattatgaat
      421 gaagataaaa ccgatgaaaa aatccttatc tcctcttttg gctgcaatcc caaaacagcc
      481 catcttgaat ttgaacatac aaaaaaagaa tgtaattcca aagcaaaaat cttggcaagg
      541 catctaattc aagccttcgc tccaggagaa actacacctg agcaggcaca ccaaatcgga
      601 ctggatctat gtgagagagt cttgagggga aagtatgaat atgtccttac aacacatatc
      661 gacaaggggc atctacacaa tcatattctg tttaacaatg tcagctttga aacaggaaag
      721 gcatatcaaa gtaataagag aagttatcat caaatccgaa cggtcagtga tgatttatgt
      781 agagaaaatg gcttgtcagt tattgatgaa aactacaaaa aatttaaaaa cagatactct
      841 acaaatggta aaacctatat ggaatatacc gaatttaaga aaggaaactc ttggaagaat
      901 aaactacaac ttactattga taaagctgtt ttaaaatcca aaacttacga ggaatttcta
      961 aagacaatgg aggatttcgg ttatgaaatc aaaataggaa aatacctttc cttccgacat
     1021 aaagataaaa gagataaggg aagatttacc agagcgaaag catctacttt aggggaagat
     1081 tatacaaaag agagaatcaa ggaacgaatc gaagattcaa ataagcaaaa tatttatgtt
     1141 aatcaggaat atcattatga aaaacgctcc tacaagaaac cggatactat tgtagatatg
     1201 aaaaacaatg aaaaggtaaa atcatctaag ggatatgaag tatgggcagg taaacataat
     1261 atgaaaacta tggcatctgc cttaaatgaa atgagaaaat caggtattaa ctcctacgag
     1321 gaattagatt taaaattaaa gaaagtggca tca
//
LOCUS       DARYUW010000136         1335 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYUW010000136 DARYUW010000000
VERSION     DARYUW010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..554)
                     /locus_tag="TVW11_002001"
     CDS             complement(<1..554)
                     /locus_tag="TVW11_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin M precursor"
                     /protein_id="HEL1366055.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPV"
     gene            complement(821..>1335)
                     /gene="spek"
                     /locus_tag="TVW11_002002"
     CDS             complement(821..>1335)
                     /gene="spek"
                     /locus_tag="TVW11_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL1366056.1"
                     /translation="VWNDNTFKKVISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKE
                     QFNYIDGGIIKTSDVKPEEKAIYINIFGEKELRTLTAKDKITFKNNIVTLQEIDVRLR
                     KSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETIDMSKVSHFD
                     VYLNEEFSKN"
BASE COUNT          448 a          245 c          157 g          485 t
ORIGIN      
        1 acgggagatt tttcaaaagt tattttatat ttcgaggtct catctttctt atgcccatca
       61 ataaaaacgt tcatgtaaat cgtttttcca gctccttttc tctcattaac tttaacgaga
      121 ccaccattga ttgaatgtat ttgatctttt gaaaatactt cagccgataa tgcaagacca
      181 aaaacatcga cattatctcc aacattaaat ttaccttcta cagatgggta taggttactt
      241 gatattataa aattataatc atcaaattcc catactttag ttttatgctg agcatctata
      301 ataacttgcg tccctctttt tccagtaacg ggtttattct ctttttttat agtatctcta
      361 ttataaattt ctcttaaggt agtaggggat aatgttttat ctacatccca ccttggagag
      421 tatatatcct taatattaat agtcccctcc gcagaaacca tcctaacaga aaataccacc
      481 aatgacaata ctactataaa aaaagtagtt gacatattaa ccaaacgaca attctgacgt
      541 aaaaaaattc tcatttatct tattattctc cttaataaat caatatagct gtgaaactat
      601 gttttttgaa cttgaacctc aaaatgctta aatcggaagt acttgagcag acttcttaaa
      661 agataataaa ctgattctat aacgcacaga aattaatctg agcggtttta tcatattcct
      721 cggttgaccg atagtgatgc ctagaagtct actaaaaccg tctaattcat caaaatctat
      781 ttaaatagac taaaaattaa attaaaatag cattcgaccg ttaattttta gaaaattctt
      841 cgtttaagta aacatcaaag tgactaactt tactcatatc aatcgtttca ttatctgtat
      901 agtcggggta agtaaataaa ttggtgtgtc taatgccacc gtctttataa tgaatatccc
      961 aaaacccttt tttatacaaa gaatcgtact catacaattt tattttgctg tctcccatca
     1021 aacttttcct aagtctaaca tcaatctcct gaagagttac aatattattt ttaaaggtaa
     1081 tcttatcttt agctgttaat gttcgtaatt ctttttcacc aaaaatatta atataaattg
     1141 ctttttcttc tggttttaca tcacttgttt ttattattcc cccatcaata taattgaatt
     1201 gttccttgca tacaacatga tatgacttta ctatagcaaa aatattcaca tgatcaccaa
     1261 cattaaacat tctttcctgt gaaggagaaa gattactaga tatgactttc ttaaaagtgt
     1321 tatcattcca aactg
//
LOCUS       DARYUW010000137         1298 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYUW010000137 DARYUW010000000
VERSION     DARYUW010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(3..605)
                     /locus_tag="TVW11_002003"
     CDS             complement(3..605)
                     /locus_tag="TVW11_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366057.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            complement(1074..>1298)
                     /locus_tag="TVW11_002004"
     CDS             complement(1074..>1298)
                     /locus_tag="TVW11_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1366058.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          400 a          241 c          218 g          439 t
ORIGIN      
        1 acttaccaaa ggttaattct attattatta ggaactgtat caatactatc aatatatcta
       61 gctatatgat atcctggcga taataaattt aacatgtaat cgactggaat ttcagctatc
      121 attttaccta gcccatattt aattagaatt gattttaccc gaccaacagc ttctcttttt
      181 ccgactctca aaacaccagc agcaattgat ccagctccac ctgttaatgc cataccaata
      241 gccacatcta gagctgctcc caattgatct actgtaaccc cttgccatgc tgagcggaaa
      301 agagtctctt cttcaggtaa tgtataatca cctactaatt gtctttcaat aacttctctg
      361 ataaaatctt cagaaactgt aggatgattt gctttaacat ttcgaacaag caattcttta
      421 tcttctacag acatttcata actttgaaca aaatacatac catctgcgtc atctgtatta
      481 ttttttatgg cacttgtttg aatatccgca aaagcaatga cagatggagt cgttgcagct
      541 gttaaaagta ataaactact agacaaaaca cctaagcgac ataaattttt ctttacagaa
      601 atcatattga ttcaccatgc ccttctttaa aaataaatgt ttagactagt ctttcaaaaa
      661 tttaagttta acattaataa attaaaaaac aagactgttt ttgaaaacat ttttatgata
      721 taataaagat attaacatta gaaaatgata tttgatgatc tagaaatagt atcataacta
      781 tcttgttaaa gaggttgaag aaattagcgc atagaaaaaa cgtatcagtt acgattatag
      841 tctagtttgt ctttatgaaa tatagataac actgtacaat ccttttcttt tattgtacga
      901 ctttatacaa agaaaagccc ttggaaatta ttttctaagg acttttttca atttgagagg
      961 ctggtgatag cctctttttg aacttaggtc atcttcttag ggcaatgctg cctgaagaga
     1021 tgagaaaagc tgttactagc tcattgccta aggggaaagg tgcaatggct ggtttagttt
     1081 ttcttgcctt ttaatgttag catgccggcg ctagcgataa caccaagggc tgcaagggtg
     1141 aagaatgggt gatttgtctc ccctgtagct ggcagtgtgc ccttttgagc tgctggcgcc
     1201 atagcttttg ctgttgattt agaatctgct ttaggtgctg atggcttagc atcttttcca
     1261 tggtgaccct tatgtccatg ctcgccttgg ccttggat
//
LOCUS       DARYUW010000138         1284 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYUW010000138 DARYUW010000000
VERSION     DARYUW010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(231..725)
                     /locus_tag="TVW11_002005"
                     /pseudo
     CDS             complement(231..725)
                     /locus_tag="TVW11_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(951..1023)
                     /locus_tag="TVW11_002006"
     tRNA            complement(951..1023)
                     /locus_tag="TVW11_002006"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(988..990),aa:Lys,seq:ctt)
     gene            complement(1025..1218)
                     /gene="ssrS"
                     /locus_tag="TVW11_002007"
     ncRNA           complement(1025..1218)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TVW11_002007"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          376 a          226 c          224 g          458 t
ORIGIN      
        1 tgggaggttg tgacaatcga gcggatatcc gatgttatgg cagaactttc tgagtctgaa
       61 taattttagt tcaccaaaga atcaagaaag aaccattggg gcaaaattgg ggcataagtt
      121 tagaactttt gtcgtttctt gtgtcgatac aataccggtt taatactaac aaatgctttt
      181 attatcgact ttgtaaccat tattgttcct tgtgtttttt cgggaataaa ctcaagaagt
      241 ttttgagttt tttcttgaat ttctttttca tatttcaata tgatgagtga aattttatct
      301 tctttggaca tagtgttgtt gtcttcaaga ttaagttctt tagttgttag agtgttttta
      361 tctaatttat tttgaaatat tgcaaaatct agaatttttt gaagtaatac ttcttcctcg
      421 gccatacggc tataaagcca attattttcg agtctctcta ggtgctccat ccacttaaag
      481 tctctttttt ctcctaacat attgtaggga aataaggtat caatatcaac atttaaggct
      541 gtagcaatct cttgaagcct atcccatgaa ggttcagtag tccccttttc gtcattaata
      601 attgtttgct tagtaactcc tattaattta gcgagttctt tttgtgtttt tccagctttt
      661 aagcgagcat ttttaatatc tatttgtcca actgttaaag cctgcgaata attaaaaaaa
      721 gccatttttc tccaaattcc gtcgcaggtg atggaggtga aaatactccg attgtatcac
      781 cttgtgttaa ttatattatt gtcatgtgtt agctctcttt ttaaaaagta ataaattctt
      841 tatttaacat catatcataa aaaattgttt cggggacaaa tggtgggaca aaccctcttt
      901 aggcaagcaa aaaagccctg caataaaggc tttttgtcgt ttttacacta taccccctac
      961 agggctcgaa cctgtgaccc atagattaag agtctactgc tctaccaact gagctaagga
     1021 ggtaaggaaa gctgtattgg caccggtgat tcacgttttg tattgaaccc gcacgatata
     1081 agcaggtggg caacatactt ctcttcagat tgcttccacg tgaaacggct tgcatactag
     1141 agatagactt tgtttcccta aaatacaaaa aaatagtcgg tcaacactta gatgtgaatt
     1201 cgtatgccac agcaataact ctatgctctt atgataccac tttttgaaaa tttttcaagc
     1261 cctaaaatga aaaaaagatc gtat
//
LOCUS       DARYUW010000139         1274 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYUW010000139 DARYUW010000000
VERSION     DARYUW010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1274
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(1..711)
                     /gene="speh"
                     /locus_tag="TVW11_002008"
     CDS             complement(1..711)
                     /gene="speh"
                     /locus_tag="TVW11_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL1366059.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
     gene            complement(737..>1274)
                     /gene="spei"
                     /locus_tag="TVW11_002009"
     CDS             complement(737..>1274)
                     /gene="spei"
                     /locus_tag="TVW11_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1366060.1"
                     /translation="ELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNSYGGIT
                     LSDGNRIDKKNIPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFN
                     IYGYGDVKDFGRSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNK
                     TAYSDQLHIDIYLVKFNK"
BASE COUNT          407 a          215 c          160 g          492 t
ORIGIN      
        1 ttagctgatt gacacatcta catgaaattg agttgagtct attctctcgt tattggaata
       61 tatttttagc atgctattaa agtctccatt gccaaaataa tacaaatcaa aaacaatatc
      121 tttacctgaa tttaaatcta aggtaacagt tcctttagag tatttttgtt cccggttatt
      181 atagatatcg tatttcttaa tcaataactt tctaactttt atatccactt cctgagcggt
      241 tactttcggt ttattgactg taataaacat aggcggatgt tgtttacttt tatcccacac
      301 gtttatagga actttaattt cttttttttc tgaattagtt aatgtaattc caccaaacgc
      361 ttcatacctt tttcctggac attcacaagc ctcttgtgca gatagagcat aaatatctac
      421 ttctttatct ttgaattcct gtgatatcca atctttctca aaaaaaactg acaaattttt
      481 atccttgaca ctatatttca acatatggct tgttacaata tctggagaat tttttatact
      541 atcggcttca attaagttag aatcatgctt ataaagcgat tctagattat gtctattggt
      601 tgtattataa gaatttgctt gaacaacatt ggaatataaa agaaatgaca aacatataat
      661 catgctgtag attttcttat caatatgtga gtagcgacaa ttatatctca ttttttctcc
      721 ttaagaagtg agagttttat ttattaaatt taactaagta tatatcaata tgaagttgat
      781 cagaataagc ggtcttatta tcactgtatt tttttagcat actctctctg tcaccatgtc
      841 ctgtatcaaa aagattataa gaaattctct ctccactatt caaatgaaaa ataatatttc
      901 cttcctcaaa gccagattga aatctagagg agcggccaaa atctttaaca tcaccgtatc
      961 cgtatatatt aaaatgtttt tgaagataat atcttgattt cacatcaagt tcctgaatag
     1021 taacctcttt cttatcagta ctcactgtac ttatatctgt atagctatat ttttgttgaa
     1081 cgccgtctat gaaaatatta acaggtatat tttttttatc aattctatta ccgtcgctta
     1141 aagtaatacc tccatatgaa ttctttttta tattagagtt acagggagga gaatactcca
     1201 aagtaaatat atccaccctt ttaccagaaa aaaatttagc tttttctacg ctattaagtt
     1261 ctacttttaa ttca
//
LOCUS       DARYUW010000140         1249 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYUW010000140 DARYUW010000000
VERSION     DARYUW010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            34..>1249
                     /locus_tag="TVW11_002010"
     CDS             join(34..484,484..>1249)
                     /locus_tag="TVW11_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1366061.1"
                     /translation="MTLSYEDKVQIYELRHIGKSIKCLSEKFSIAESDLKYMIRLIDR
                     YGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTSLDYALPNSSMLSRWIAQYKKN
                     GYTILEKRRGRPPKMGRQPKKTLEQMTELERLQKELDYLRAENAVLKKPERIPVEGRS
                     KAQRATEIIQELIGQFSLATLLEILDLSRSTYYYQVKQLAQEDKDMDLKELIQGIYDE
                     HHGNYGYRRIHLELRNRGFIVNHKKVQRLMTVMGLKARIRRKRKYSSYKGEVGKKADN
                     LIKRQFEGSKPYEKCYTDVTEFTLPEGKLYLSPVLDGYNSEIIDFTLSRSPDLKQVQT
                     MLEKAFPADSYNGTILHSDQGWQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFF
                     GILKSEMFYGLETT"
BASE COUNT          413 a          235 c          268 g          333 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg
      841 ttggcaaaaa ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga
      901 agtgctatac cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg
      961 ttcttgacgg ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga
     1021 agcaagtaca aaccatgctt gagaaggctt ttccagcgga ttcgtacaat ggaacgattc
     1081 tccacagcga tcaaggctgg caatatcaac atcagtctta tcatcacttt ttggagacta
     1141 aaggcattcg tccatccatg tctcgcaagg gaaatagtcc agataatggg atgatggagt
     1201 ccttctttgg tattctcaaa tctgagatgt tttacggcct tgagacaac
//
LOCUS       DARYUW010000141         1139 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYUW010000141 DARYUW010000000
VERSION     DARYUW010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(1..262)
                     /locus_tag="TVW11_002011"
                     /pseudo
     CDS             complement(1..262)
                     /locus_tag="TVW11_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003081814.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
BASE COUNT          348 a          152 c          189 g          450 t
ORIGIN      
        1 atcaattgga tctaaaattc ctactgcttt tagtttatta aaggataggt aagaattatt
       61 ttctataata gcctttgctt taacatagtt aaagtataaa atatcattag aataaacagt
      121 ataatattgt ttaaagaagt ttgaaaccac attagtgcct gcaaataaat ctaaaaaaaa
      181 cttcttcatc accagtttta tgtttgtcta gcatggtctt aatttctgtc aacaataatt
      241 ttttagaacc aatatatctc attctacatc cttaatcatc ctttagttgt ttcattatag
      301 catattcatg ttgaagttcc aatattttat ttgaaaaatt atcttttgct gtatttcttt
      361 attgtagttt ttaagcttag tttatatgtt gttgattaaa gggaagaaga acttaggtta
      421 tctaaattga ggaattcgtc tgtaggtaac aatgtattat gtggccgaga gatttatttt
      481 atatattaat gagatataag acccctatcc cgtccagcgt gacagacttg ctatggaaaa
      541 gcttattttg aggctgtctg aggcttgctt atgtgtgaca agcatttagg ctagaacgct
      601 cacctttttt actgcaagca aagctttaga agctattgca agatactttt aggcttgtta
      661 ctaagcgggt catctctatc atctcctaga gagtagtgga ggctatgaca gtttagcata
      721 tatggtttct ctaatgattt gacgatgtaa aaccataact actgttattg tagggattat
      781 gtataatatg tataaaaaga gaagggcttg tttctcagcg ttatcatttt acctataatg
      841 tcgctgccag tttgcaaggc tgctgagatt agtagctttt tggctatttt tctcatcttt
      901 tgtcttattt ttattaaaaa taatgaattt ataaagataa tttttcaaag aatagtcttt
      961 aagttgacag tagtatcatg tggcgatttt tgtcttggtt tttgcattta tttcggtttt
     1021 tttatcttta attaagttac taatattctg attatgttag taaaatgaca ttctcataaa
     1081 atgtctaaaa aaggctaatt tgtcaaggta ttatcataag gcttgatttt ataagctat
//
LOCUS       DARYUW010000142         1077 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYUW010000142 DARYUW010000000
VERSION     DARYUW010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            41..>1077
                     /locus_tag="TVW11_002012"
     CDS             41..>1077
                     /locus_tag="TVW11_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1366062.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT          337 a          209 c          228 g          303 t
ORIGIN      
        1 tttttcttgt tgtgtatggt tatatatgtt ataataaact atggctttta ttaaaacaac
       61 aacgaataaa gaaggtagga cgcatgtcta ccttgtagaa gggtatcgta aagatggtaa
      121 ggtcaaacag cgtatcctta aaaaatttgg tctcttagat gagcttgaat tggaagaacc
      181 agggattctt gagcgtctta agcgcgaagc taaagaagat actttaaata accctaaggt
      241 actccaggtt tcctatgacc tccttgcccc catgaaccaa ccggatcaat cttatggttg
      301 gatggttttg gataatctct tcgaatctct ggggctcaca gcctttttaa agggtatcaa
      361 aacgaagtct gagtatgact tagtgcaagt gctaaagcta ttagtttttc agagaattct
      421 ccgaccagat agtaaacttg ccacctatgc ctctcaagca gacttatttg gccattggga
      481 catcagctta aatgccattt atcgctcctt gaacaaattg aacaccttga aagatgatct
      541 tcaacatcat cttcacaagg tagtgagtca gatgatcaaa cgtgaagcca gtctcgtttt
      601 ctacgatgtc accaattatt attttgagac agatattcca gataacgagt tggtttcaga
      661 aaatggagag atactacaag aagggcttcg aagacgtggt ccgagtaagg aacaccgtcc
      721 aaaacccatt gtgcaattag gactctttag ggataccaac ggtattccga ttagctataa
      781 actgtttcga ggtaatcaaa ccgatcctgt tacctatctt ccagcggttg aggaagtcaa
      841 aaaacaattt ggaattgagc ggttaattgt agtcgccgat aaggcgatga atagtatggc
      901 taatgtttca gaaatgctca agcaagaaga tggctggctc ttctcacaga aacatcgcgg
      961 acgccgagga gctccaaaag atattcaaga acacatcctt gattcatcgg attggcaatt
     1021 taacccagaa cttaccttcg ctaagaaatc ttatatccgt gaacggaagt tagggaa
//
LOCUS       DARYUW010000143         1044 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYUW010000143 DARYUW010000000
VERSION     DARYUW010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(45..755)
                     /locus_tag="TVW11_002013"
     CDS             complement(45..755)
                     /locus_tag="TVW11_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1366063.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
BASE COUNT          303 a          212 c          179 g          350 t
ORIGIN      
        1 ggctagaact caagccttgg agtgctaagt catttttcta ttctttagta gcccattcgt
       61 tgtgcccatg ccttatcaat agcaagggtt tcagtgtctg tatagctctt gcgataagga
      121 ttccagacag aggtcaaagg agccgcagca agcgcttctt gcgcctgatt atttactata
      181 tcataggccg ttagaccgta ggtctcaatg atgttgttta atttccagtt atagctagta
      241 tctgtagcat acaagcctgt taaagctgct gtagcgtcct gataagacaa ggtatttgac
      301 tttctagcac ctgcataaat atctgagcta agcaaattag tgtaatcata taaggaatca
      361 gccactgtcg gataagctct aaaggtttga tcgatgtagt aagtatttcc agccccatcg
      421 tcttcccatg ttgtcatcgt cactgatgac ccattataag cccctttaat gccaaaaaaa
      481 ttataataag gtgcttgact taaagctgat ttaccgttag ctgactctaa aatagcttga
      541 gcaatcataa ccgaagcata caagtctctt tcttgagcaa caacactagc agttgctcca
      601 atctcttcaa taaaggcttg cgttgacgac gttgacacag tctctgctga gacatctgat
      661 gtattttctg actgtctaat tgaactataa acacctaagc aggctactag aacaaaaaga
      721 ctgataagtg tgagcttacc tttctttttt gccatttatc attccctctt tttttgataa
      781 atagattata gcacagaatg ctcataaaaa gacttatcca caaacaattt aatcatattg
      841 ataacttttg tctttaaatc gaaatatttt aatgtaaaga aggcttacca agtccataaa
      901 gcgaaggctt ttcataatct tttacgcctt atttgctata tcgccttgta atagcttcaa
      961 tacctttgaa aggttattac acctactatt gttctttatg cctgtctgtt aagtattttc
     1021 catttaactg cctttatttt ttag
//
LOCUS       DARYUW010000144         1038 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYUW010000144 DARYUW010000000
VERSION     DARYUW010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            6..380
                     /locus_tag="TVW11_002014"
     CDS             6..380
                     /locus_tag="TVW11_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1366064.1"
                     /translation="MLRKVDISMFSTFEKIKELCKSRGISIAKLEENLGLSKNAIYAI
                     KRNQPSAERLQEIADYFHVSTDYLLGRTDNPKIAQSDHTPSAIDLKKDAEETFFFDGH
                     ELNDEDIDLITSILETRIKNRK"
     gene            394..798
                     /locus_tag="TVW11_002015"
     CDS             394..798
                     /locus_tag="TVW11_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1366065.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     TYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLREELSYWDNVEEFNYVR
                     FMQQYDLTSFVDEVMVKEEYYNLTGYYDKKSF"
     gene            826..>1038
                     /locus_tag="TVW11_002016"
     CDS             826..>1038
                     /locus_tag="TVW11_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1366066.1"
                     /translation="MSSNTYYKNLTNKKIINYLQSSHTGRIYKYNYLKSNEVKLVREP
                     NNKHDQNAVKILVKNIFIGYIPHEIAK"
BASE COUNT          403 a          180 c          183 g          272 t
ORIGIN      
        1 tcgtgatgct tagaaaggtt gatatatcaa tgttttcaac attcgaaaaa atcaaagagc
       61 tttgcaaaag tagaggaatc tctattgcaa agctagaaga aaatcttgga ttaagtaaaa
      121 acgctattta cgcaatcaag agaaaccagc cgtccgctga acgtcttcaa gaaatcgctg
      181 actacttcca cgtctctaca gattaccttt taggtcgcac agataatcct aaaattgcac
      241 aaagtgacca taccccgtct gcaatcgatc taaaaaaaga tgcagaagaa actttcttct
      301 tcgatgggca tgaactcaac gacgaggata tagaccttat cacatctata ttggaaacgc
      361 gcatcaaaaa tagaaaatag agaggacagc tctatgatga caccagaaac agtctgtcag
      421 gaaaagggaa tcgatttagt gtacttcgac ggtaggggga caaacacccc tggaatgttt
      481 aacaaaaaac acaacgtcat tgcgattgac acttatcttg acggcacata caagcacaaa
      541 gtcatctatc atgaactagg acatagagaa catactgcga gttattacaa gctaaacaaa
      601 gaaaaagcag agctacaagc tgatagatgt atgatacatc acttgctgag ggaagaattg
      661 tcttattggg ataatgtaga ggaatttaac tacgtccgat ttatgcaaca atacgatcta
      721 acttcatttg tcgatgaagt catggtcaag gaagagtatt ataatttaac aggttattat
      781 gacaaaaaga gtttttaatt ctagctttca agtagctgga acagtatatc atcaaacact
      841 tattataaaa atttaacaaa taaaaaaatc attaactatc tacagagtag ccatacaggc
      901 agaatttata aatacaatta tctaaaatca aatgaagtta aattagtacg agagcctaat
      961 aataaacatg atcagaatgc tgttaaaata ttagttaaaa acatttttat aggctacatt
     1021 ccgcatgaaa tagctaaa
//
LOCUS       DARYUW010000145          956 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYUW010000145 DARYUW010000000
VERSION     DARYUW010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..>956)
                     /locus_tag="TVW11_002017"
     CDS             complement(<1..>956)
                     /locus_tag="TVW11_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1366067.1"
                     /translation="WNSIFYDANLNCCKQISVGGSIVYILEKRIQFVDIETIKAKMRN
                     MVPIYMVPDDIVLLKNMPQNKNGKVDRKKLEEIYKDKKLQGNIFDMILDDREIETLKD
                     IWKEIFGYDTKYRTSFFSNGGDSLIATKLSAKIEEKFKISFSIKDVMENITIEAQAQV
                     IKDRIAEQRFADKISVIEETITEEEFDLTDVQHAYYVGRNKDMILGGVSTHCYFEIES
                     SDIDVNKLEKAWNYLIKIHPMLRAIITENGKQKILQEVEYYKIMTSADSELIIRDIMS
                     QQVLNLDKWPIFDIRISKREDKADIIHISFDNIILDGWSMFF"
BASE COUNT          290 a          198 c           87 g          381 t
ORIGIN      
        1 tgaaaaacat actccatcca tccaatatta tattatcaaa actaatatga attatatccg
       61 ctttatcctc acgcttgcta attcttatgt caaatatagg ccatttatcc agattaagca
      121 cctgttgtga cataatgtca cggataatga gttctgaatc tgcactagtc attattttat
      181 aatattctac ctcttgcagt atcttctgct taccattttc agttataatt gctcgtaaca
      241 tcggatgaat ttttattaaa taattccacg ctttctccaa cttatttaca tctatatcac
      301 ttgattctat ttcaaaataa caatgagtag aaactcctcc taaaatcata tccttgtttc
      361 ttccaacata ataagcatgt tgaacatccg tcaaatcaaa ctcttcctct gtaatagttt
      421 cctctatcac gctaatttta tccgcaaaac gctgctcagc aattctatct ttaatcactt
      481 gggcttgtgc ttcaatagta atattttcca ttacatcttt tatactaaaa cttattttga
      541 atttttcctc tattttagct gatagttttg ttgcaattag agaatctcca ccatttgaaa
      601 aaaagctagt tctatacttt gtatcatatc caaatatttc tttccatata tcctttaaag
      661 tttctatttc tctatcatct aaaatcatat cgaaaatatt accttgcaat tttttgtcct
      721 tatatatttc ctctagtttt ttcctatcaa ctttcccatt tttattttgt ggcatatttt
      781 tgagtaatac tatatcatcc ggcaccatat atatcggaac catatttctc atcttcgcct
      841 taatagtctc aatatcaaca aactgtattc ttttttctaa tatatataca atacttcctc
      901 caactgatat ttgcttacaa caattaagat ttgcatcgta aaaaatacta ttccat
//
LOCUS       DARYUW010000146          917 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYUW010000146 DARYUW010000000
VERSION     DARYUW010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            104..917
                     /locus_tag="TVW11_002018"
                     /pseudo
     CDS             104..917
                     /locus_tag="TVW11_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          333 a          151 c          203 g          230 t
ORIGIN      
        1 aagttacgat gataaattaa gaatatatga actaagaaaa aatgggatgt cttgttcccg
       61 cattggtcaa cagtatgata ttcaggtttc taatctcaaa tacatggtaa agcttatgga
      121 cagatatgga gttgagattg ttagaaaggg taaaaataag tattatcctc cagaattaaa
      181 acaagaaata attgataaag ttcttcttga aggtcagtct caactgtctg tctctcttga
      241 gtatgctctc ccaaatgctg gtatgcttcc caattggata gcgcaataca agaaaaacgg
      301 gtatactatt cttgagaaac aaagagggag accaacgaag atgggccgta aaccaaagaa
      361 aacttgggaa gaaatgacag agctagagcg ccttcaggaa gagctagaat accttagaac
      421 ggagaatgct tatctaaaaa agttgaggga gcttcgttta caggacgaag ccagagaatg
      481 agaaaggcag aaacaattag agagatggtc caagaaggat tccgattaaa cctcctactt
      541 gagatcgcta agatggctcg ttcaacctat tattatcaag tcaagcaatt ggataagtca
      601 gataaagatg aagcaatcaa ctctgaaatc aaagcgattt atgaggagca taagggaaac
      661 tatggttacc gtcgcattca tttagaactc aagaatcgtg ggtttatcgt caatcacaag
      721 aaagtgcaac gcttgatgaa agagatgaga ttagctgctc gaattcgtcg taaacgcagg
      781 tattcctctt acaaaggcga gactggtaag aaggctgata atctgattca acgccagttt
      841 gaagctgcta agccatatga aaaatgttat accgatgtga cagagtttgc tttaccaaac
      901 aacgatgaaa aacttta
//
LOCUS       DARYUW010000147          917 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYUW010000147 DARYUW010000000
VERSION     DARYUW010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            42..902
                     /locus_tag="TVW11_002019"
     CDS             42..902
                     /locus_tag="TVW11_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1366068.1"
                     /translation="MLNKMGESFKIMRKSRGITLSEATGEEFSESMLSRFENGQSEMS
                     AQKLFACLDNIYLDIEEYNLLVREDEPTDFSTLQKNIHHFYNPYNEIELEKLAKKELD
                     KIKIDGREQYHRLNNILIKARIKSVNNNYFISDDLIEYLKNYLFSMVNWANYELTLFS
                     ETIHLFEPNAFLNYCQEMLHRSDFYKRLSYNSAIIQTILINGVFYSVEKNRLEDALIL
                     IETIKQNFSQTRDAYLKIVFMIAKGYYLTKFDKNKGIFLIKKGINIFKDLGYEEISTY
                     YYNEFKNIID"
BASE COUNT          367 a          111 c          133 g          306 t
ORIGIN      
        1 ataatattaa taagaataag ttaaattagt aggagaggta tatgctaaat aaaatgggag
       61 aatcatttaa aattatgaga aaatcaaggg gaataacttt gagtgaagca actggagaag
      121 aattttcaga atctatgctt tcccgttttg aaaatggcca atccgagatg tctgctcaaa
      181 aacttttcgc ttgtttagat aatatttatt tggatataga agaatataac ctattagttc
      241 gagaagacga acctacagac ttttctacac tacaaaaaaa cattcatcac ttctacaatc
      301 catacaatga gattgagtta gaaaaattag cgaaaaagga actagataaa attaaaattg
      361 atggtcgaga acaatatcat agactaaata atatattaat taaagctaga atcaaatctg
      421 tgaataataa ttattttatc tccgatgatt tgattgaata tctaaaaaat tatctctttt
      481 cgatggtaaa ttgggcaaat tatgaattaa ctcttttctc agaaactatt catctgtttg
      541 aaccgaacgc atttttaaat tattgtcaag aaatgctaca tcgttctgat ttttataaaa
      601 gactttctta taatagcgct attattcaga caatactaat aaatggtgta ttctatagtg
      661 tcgaaaagaa tagactagaa gatgctttaa tattaattga aacaataaaa caaaatttct
      721 cacaaactcg agatgcttat ctaaaaattg tttttatgat tgcaaaaggt tattatttaa
      781 caaaatttga taaaaacaaa gggatttttt taattaagaa gggaatcaac atctttaaag
      841 atttaggcta tgaggaaatc tcaacttatt actacaatga attcaaaaat atcatagatt
      901 gaatttttgc ttatatt
//
LOCUS       DARYUW010000148          890 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYUW010000148 DARYUW010000000
VERSION     DARYUW010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..>890)
                     /locus_tag="TVW11_002020"
     CDS             complement(<1..>890)
                     /locus_tag="TVW11_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1366069.1"
                     /translation="LMFSAGTAIENTEELGFSHLIEHLLLRSGGEQSLNELFDNNGAF
                     IGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTEEELLREKRVVLVELTQYEN
                     GSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKLYKFYTENIQNGEFQIAISG
                     PNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKNQQVSEISMYIDISKMTTSS
                     HDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFPIFYNGLTILKILTRTPEIH
                     KHQVVQVLKEDLVNREDLKN"
BASE COUNT          275 a          165 c          106 g          344 t
ORIGIN      
        1 tattttttaa gtcttctcta tttactaagt cttcttttag aacttgtact acttgatgct
       61 tatgaatttc aggcgttcta gtcagtatct ttaggatagt gagcccattg taaaagattg
      121 ggaatgaaat tatattatat acccattggt ttttcgtcct taatttacct cctaacactg
      181 aacccttaac tcctgttaac atcgcattta aaattgttaa tatcgctaca tcatgagatg
      241 atgttgtcat ttttgaaata tcaatataca ttgaaatttc agaaacctgt tgatttttct
      301 ttcgttctgt tacaccacta gaaaaaatag gaaaattaga tttaacagga gttcttccaa
      361 ctggtaattt attttcaata atcgctattt cttcttttaa gtgattcggt cctgaaatag
      421 caatttgaaa ttctccgttt tggatattct cagtgtaaaa cttataaagc tttttcaaat
      481 caacagattc aatattctcc ctaacaccaa taatatcttc tgaccactta ctatttttaa
      541 aaattaggcg gttatccgaa actaattttt ctgttttgct cccattctcg tactgtgtta
      601 gttcaactaa aactaccctt ttttctctta gcagttcttc ttcagtaaga tttaaattaa
      661 ataccctact tactattgct tcaaatatat ttttgaaatt ttcagcctta cagtaaccca
      721 tcaaattaat ataatctcta gaagtttcac ctccaataaa tgcaccatta ttatcaaata
      781 gttcatttaa tgattgttct ccgcctgatc gtaataataa atgctctatc aaatgtgaaa
      841 aaccaagttc ttctgtattt tcaatggcag tacctgcaga aaacatcaat
//
LOCUS       DARYUW010000149          821 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYUW010000149 DARYUW010000000
VERSION     DARYUW010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            134..517
                     /locus_tag="TVW11_002021"
     CDS             134..517
                     /locus_tag="TVW11_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1366070.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            625..>821
                     /locus_tag="TVW11_002022"
     CDS             625..>821
                     /locus_tag="TVW11_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366071.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKNDL"
BASE COUNT          296 a           88 c          183 g          254 t
ORIGIN      
        1 atggaggtgg agttttatga attacaataa tcctcatagg tataggaacg gagattgagt
       61 agagttttgg gaaactttat tcggaagaaa aattttacaa aaaatttaag tatttgagag
      121 aggagaattt atcatgaaaa aagcattgtc attagtatta ttaacaggtt tgatgttagc
      181 atcatctgta ccagcatttg cagcagaaga aacaaacttg ccatatgttg aaggtcttgg
      241 ttatgaggtg gaagtatttg aagaagatta tactcagcca aagttgttca gttatgatag
      301 cggatggaaa agttttttag gtggaaaatg gagacatggt gtaggtagtc gatatgtttg
      361 gtctaaatac gatcacaata ataaaacaca taaaactaca gtacaaggtg ctggtggtca
      421 attctcttat tcgggttgga caagcgctgg aagtagagca gaagcttctt gggaaaaagc
      481 tttaagtggt aatagggctt gggctgatgt taaataacaa taaataaaaa atagttgaac
      541 gagtttgagc ggtgccacgt tgttatttta gcattgtggc attactcata ctcgctattt
      601 ttataaagtt ggagatgata cagaatgaaa aaaacagtgg gtatattggc aattttacta
      661 attatagtga ttggtatagg aaagtttttc tattcagacg gcatgttttt aaatatattc
      721 ataaaagagt ttaatactac tgtaaacatt gtaacaaagc cagaaatagc tgataaaaca
      781 ataattgaat tgcagaaaat agctaataaa aatgatttaa g
//
LOCUS       DARYUW010000150          794 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYUW010000150 DARYUW010000000
VERSION     DARYUW010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            222..>794
                     /locus_tag="TVW11_002023"
     CDS             222..>794
                     /locus_tag="TVW11_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1366072.1"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKLGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISGLDNNHQLTNQDISYLSNYLFSLENWGYYETLILGNCC
                     RSLPPKLLFKYTKEALKKGKLYNSIPRNKQS"
BASE COUNT          309 a          120 c           95 g          270 t
ORIGIN      
        1 atttttctta gtgaaaggtg acttgactat tgcttaattt aaatattaaa tcataaaatt
       61 gagtactaaa aacttatagg cattatactt catgcaatct acaaaaatta ttgacataaa
      121 cctataataa tgataatatc aagaatcaat ttaagtaact tgtaactttt tctcatcatt
      181 tgtcacgctt tccacttttt aactacaaac ggagataatc tatgatctta ggtgaaacct
      241 atagaaaaat gcgggaagaa aaaggaattt ctatttcttc attagcagga tatgaaattt
      301 caaaatctca aatttcaaga tttgaattag gagagacgga aatttctatt ttcaagttat
      361 tatatttact agaaaaactc ggaataacct ttgaagaatt cttgctcgcc tgtaacaatt
      421 atgaaccatc tgaatttaat acactaataa aagctgttca aaattctgca tacaataata
      481 aagtcgaaac actaataagt atgatagaac aagaaaataa attgtttgaa gagacaaact
      541 ctcattatca taaattaaat tcaattttta tccaaagtat catttctgga cttgataaca
      601 atcaccaatt aactaatcaa gatatctctt atctttcaaa ttatttattt tccttagaaa
      661 attggggata ctatgaaacc cttattcttg gaaattgctg tcgttcttta cctcctaaac
      721 tattattcaa gtatactaag gaagctctaa aaaaaggaaa attatacaat tcaattcctc
      781 gtaataaaca gtcg
//
LOCUS       DARYUW010000151          723 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYUW010000151 DARYUW010000000
VERSION     DARYUW010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..700)
                     /locus_tag="TVW11_002024"
     CDS             complement(<1..700)
                     /locus_tag="TVW11_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1366073.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPE"
BASE COUNT          219 a          157 c           87 g          260 t
ORIGIN      
        1 tttcaggaga tgtatttaca aacatatgct tgccattaat atatctgtaa gagaattctt
       61 tcgtcgtata atcttgccat tttaaaagtt cttcaagttc catttcttca tcaatatcac
      121 ccatcagacc taaaatcttg ctattcaatt tttccccttt tgtatcctgg tagtcctcat
      181 cgataataaa atcggctctt agtgttggta aaaaaatccc aatcaaatct ttattgtcta
      241 atatctcatt tggagtacca tcatatcttc ttaacccttc aataaatcct tcatcatcta
      301 aatgataaat cggattcggt tccttatagc aaggggctcg cccagctgat atgataattc
      361 cattcggatt tggtaaccca ttttctttaa ttttcagagc caattcataa gcaatcttag
      421 ttcccatact atgcccgaaa aaataataag gtgagttaaa atcaaaagtc atttttaagt
      481 cttcaaacaa tccttttaca agttcttcta tgttgctaat tgctttttca gaaaacctgt
      541 tttctctccc tggatactgt gcaacgaaga gatttatatc tttaaattga ttaccccatc
      601 ttctgaatga tgatactcca ccacctgcaa atggaaacac aaataaacta gctttcgtgt
      661 tttccatttc tttattaacg tattcgaacc acattcccat caaaacacct tccatctgat
      721 tat
//
LOCUS       DARYUW010000152          679 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYUW010000152 DARYUW010000000
VERSION     DARYUW010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..403
                     /locus_tag="TVW11_002025"
     CDS             <1..403
                     /locus_tag="TVW11_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1366074.1"
                     /translation="LNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIVFLLIY
                     QYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQVELLYI
                     GIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            403..>679
                     /locus_tag="TVW11_002026"
     CDS             403..>679
                     /locus_tag="TVW11_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366075.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENK"
BASE COUNT          251 a           90 c          106 g          232 t
ORIGIN      
        1 tttgaatttt tcaatcaatc cagtcgaggt ttaccaaact gtaaaactta atattcaatc
       61 cttagagcat caaattttcc tttcaaaaat actgcaaata attatttgtg gaatcgtatt
      121 tctactcatt tatcagtatg ctcaaatgtt tgttgcctta aaacagaatg actatgttaa
      181 aaaaatcatt ttaggcctat cgaaaacacg tatagccatt tcaagtctca actattttat
      241 tgtgactatt acaatggtta ttctattgac atttatgttg acaggacaag tagagctatt
      301 atatattggc attgcttctt taatggtttt aattttttca acaataatga gttttagaaa
      361 attatctgaa aaatatacac aaattctaaa aggagatgac taatggcaat tgaagttttg
      421 aatgttacca aaaaattcgg ctcaaaaaag atattcacag atttaaattt aacgtttgaa
      481 gctggaaaaa gctacgcatt gattggaggc tctggttcag gtaaaagtac actacttaat
      541 atcataggaa gactagaaaa aattgacagt ggaaaggttt tagttgatga gcaggatatt
      601 tggaagacaa aagaaagaac tttctttaaa actattattg ggtatgtatt ccagaattat
      661 tctttaatag aaaacaaaa
//
LOCUS       DARYUW010000153          659 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYUW010000153 DARYUW010000000
VERSION     DARYUW010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            87..>659
                     /locus_tag="TVW11_002027"
     CDS             87..>659
                     /locus_tag="TVW11_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366076.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDE"
BASE COUNT          263 a           66 c          136 g          194 t
ORIGIN      
        1 gaagctttat atgttttggc atagaaattt tacaactaaa gaaaagtgaa agaagcattg
       61 tacttaggtt aaaggagggt tgttaaatgc aaaatgaaaa ggaattgcaa ataaccttaa
      121 gaaatgtctc taagaaatat ggagaacaca gtattttgga aaatattagt ttggatattt
      181 ataaaggaga ttttgtttgt atctttggga aaagtggagg aggaaaaaca acacttttaa
      241 atataattgg gacattagaa aattatgata gtggtagtgt aacctgtttt tcaaatcgag
      301 atcctataaa agctcctaaa gtaggagagc tattacgcag agaaaaaatt gcttatttat
      361 ttcaaaattt tgctttggtg gaaaaaatga cggttgagga aaatatgatg cttgctgcaa
      421 aatacaatca agaaaaaaat aagaaaaatc ttatagaagc tgccttgaat aaaatgggca
      481 tttcagacaa attaaaatcg aaggtttatg aactttcagg tggagaacag caaagggtag
      541 ctcttgcaag aaatatgata aaaccgtttg aaattatgtt ggcggatgaa ccgacaggtt
      601 ctcttgatta tgagaataaa aaaattgtaa tcgatacact tattagatta aatgatgaa
//
LOCUS       DARYUW010000154          635 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYUW010000154 DARYUW010000000
VERSION     DARYUW010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            185..>635
                     /locus_tag="TVW11_002028"
     CDS             185..>635
                     /locus_tag="TVW11_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1366077.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGDQGQK"
BASE COUNT          252 a          114 c          153 g          116 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaagggtg accaaggcca aaaag
//
LOCUS       DARYUW010000155          632 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYUW010000155 DARYUW010000000
VERSION     DARYUW010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..286
                     /locus_tag="TVW11_002029"
     CDS             <1..286
                     /locus_tag="TVW11_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366078.1"
                     /translation="KVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTG
                     ALDSEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
     gene            283..>632
                     /locus_tag="TVW11_002030"
     CDS             283..>632
                     /locus_tag="TVW11_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366079.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKL"
BASE COUNT          259 a           75 c          120 g          178 t
ORIGIN      
        1 aaaagtagga ctttctaatg actatttaaa tcagaaaata tatgaattat ctggaggaca
       61 ggttcagcgt gtagctattg caagaatgtt aatgaagcca cgtaaaatta ttttagcgga
      121 tgaacctaca ggagctttgg atagtgagat tggaaaagaa atcattaatt tattattgag
      181 tgaaacagcc gaaaataaat atgttattat agcaacacat gatccagctg tatataataa
      241 ggttgatgtt atcattgatt tgaaagatat agggagtgag atatgaaaaa gaaagcttat
      301 atgacgttga tattattaat tggaatactc gcaattttct tagtgggaaa acaagtaata
      361 aaaaaagaaa atcccaataa acctacggta gatttaacag tctatacgat ctcttctagt
      421 gatacccaaa aatggaataa agtaagacaa ttagaaacag aagaagccat atacctaata
      481 agggtaaaag aagcagcatc ttcagaagaa atattttcaa acatcattgc agacggagct
      541 gctatgggtt ttggagttag tgaagaagat gttaaacaat tcaacaatca tttagagaat
      601 actatagaag attctaagaa taacaaatta at
//
LOCUS       DARYUW010000156          625 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYUW010000156 DARYUW010000000
VERSION     DARYUW010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            139..540
                     /locus_tag="TVW11_002031"
     CDS             139..540
                     /locus_tag="TVW11_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1366080.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
BASE COUNT          255 a           65 c          114 g          191 t
ORIGIN      
        1 agtattagaa tatagaacaa ataagacttt atattttcat ttttatttta gaggatcttg
       61 cacgtcaaaa tgcagaggtc ctcctttttt attcaaaaaa taagtttgaa atttttgata
      121 aaaaggaggg ctttacaaat ggcagttaaa agaaaatata tctatgtaaa aggtcaaaag
      181 atttatgtac ctgacgaagt gtatagagca tataaaaaag ggcttaatca tgaaactcat
      241 ttaaagagat tggatagaaa gcatggcgta tttcgttttg gagactttaa cacaagtatt
      301 gtagatattg cagataatac tgttgatgtt gaaaaaatca ttgaaacaaa aatgctgata
      361 gaagatctgt attatgcatt agacagttta aatgatgaag agagaaaact aattgaagca
      421 ctatattttg atgataaaac tctcacagaa gttgcaaaac aaagagacac aaatccaatg
      481 aaaatcagta gattaagaaa taagatttta gaaaagctga gaaaattttt ggataagtaa
      541 attaagtaga gggcagggaa acatctctgt cctctatttt tgaaaatttt tcaaaaatag
      601 tgttaaaagt tgtcctgaaa gtaag
//
LOCUS       DARYUW010000157          603 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.159, whole genome shotgun sequence.
ACCESSION   DARYUW010000157 DARYUW010000000
VERSION     DARYUW010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..603
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.159"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            25..>603
                     /locus_tag="TVW11_002032"
     CDS             25..>603
                     /locus_tag="TVW11_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1366081.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMK"
BASE COUNT          210 a           73 c          119 g          201 t
ORIGIN      
        1 agataaagga ggtggagaag ttacatgagc aacaaaaact ggataaatac tatattagat
       61 tttgcttcag attgtaaagg aaagttgatt ttatcagtag ttatggctag tataggagtg
      121 ttctttagca ttatacctta ttggtcagta tataaactta tggcagtctt tatagaacaa
      181 aaagcaactg gagaagatgt attgtattat ggagcgattg gtattattgc atattttatc
      241 agatatattt gccatggagt atcaacaata ttatctcata tatccgctta cacaatctta
      301 agaaatataa gagaaaattt aggtgaaaaa ttgctcagta tttctatggg aaatgcgtca
      361 aaaaagacaa taggagaata taagtcaatt attgtagaca aagttgaaac aattgagatg
      421 cctctagcac atatcatacc agagtgtgtt gctgcattgc ttttatcact aggtattgca
      481 atatttatgg tcttcataag ttgggagatg gctcttgcga tgtttattac agtgcctttt
      541 gctttgatgg catataaaaa actaatgggt aattttaatc agctttatga agctcaaatg
      601 aaa
//
LOCUS       DARYUW010000158          590 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.160, whole genome shotgun sequence.
ACCESSION   DARYUW010000158 DARYUW010000000
VERSION     DARYUW010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.160"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(109..>590)
                     /locus_tag="TVW11_002033"
     CDS             complement(109..>590)
                     /locus_tag="TVW11_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366082.1"
                     /translation="LFNDTIENNIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGYET
                     IVGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGK
                     TVIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
BASE COUNT          173 a          129 c           53 g          235 t
ORIGIN      
        1 taaatataat tatcttccca tttagacact ttttccataa aaagcgaacc tatattacca
       61 ttgcaaccta aaactcctat attatacata aacctcctcc tatctatatt atattttcca
      121 gtcctctgtt ttacccctga ttctcatata atctctatac agaccatctt ggctcatcag
      181 ttctgtatgc tttcctattt gagcaatctc tccttctttc aaaacaatta tctgatctgc
      241 ttcttcaatt gttacaattc tatgagcaat aataattaca gtcttacctt tactcaaatt
      301 cgatattgct ctttgaatta aatattcgtt ttcaggatct atgcttgatg ttgcttcatc
      361 caaaataata attggagcat cttttagcat tgcccttgct atagatattc tttgtttttc
      421 tccaccagat aaaaaatcac caccttcacc aacaatagtt tcatatccat ttggcaaatt
      481 cattataaat tcatgacaat gtgacttctt cgctgcattt attatttctt ccttacttac
      541 attcggatta ccaaatttta tattgttttc gattgtatca ttaaacaaat
//
LOCUS       DARYUW010000159          576 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.161, whole genome shotgun sequence.
ACCESSION   DARYUW010000159 DARYUW010000000
VERSION     DARYUW010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.161"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>576
                     /locus_tag="TVW11_002034"
     CDS             <1..>576
                     /locus_tag="TVW11_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1366083.1"
                     /translation="NYNKIRDVDIFNRILSFAIENIGSTFSANSIKKYLKNESRGVSV
                     DTILNYLEYCNRAFILKKVQRFDTVGKKKLKVDEKYYLTDHGFRQARGYSNTKDIERT
                     LENIVYIELVSRGYRVEIGKVKDLEIDFIASKDNERLYYQVSYLMETEETRKREFGVY
                     DFVRDNYPKFVLSMDKVDFSQNGIIHKNVIDF"
BASE COUNT          227 a           52 c          111 g          186 t
ORIGIN      
        1 aattataata agatacgaga cgtagatata tttaacagga tattatcttt tgctattgaa
       61 aatatcggat ctactttttc cgccaacagt ataaaaaagt atttgaaaaa tgagagcaga
      121 ggagtatctg ttgatacaat tttaaattat ttagagtatt gtaatagagc tttcatacta
      181 aaaaaagtac aaagatttga tactgtagga aaaaagaagt taaaggttga tgaaaaatat
      241 tatcttacag atcatggatt taggcaggca agaggatact ccaatacaaa ggatattgaa
      301 agaacattgg aaaatatcgt ttatattgaa cttgtttcaa gaggatatag agttgaaatc
      361 ggcaaagtaa aagacttgga aattgatttt attgcaagta aggataatga aaggttatat
      421 tatcaggttt cttatttgat ggaaacagaa gaaacaagaa aacgagagtt tggtgtgtat
      481 gattttgtta gagataatta tcctaaattt gtcttatcca tggataaagt ggattttagt
      541 caaaatggaa ttattcacaa aaatgtgatt gacttt
//
LOCUS       DARYUW010000160          574 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.162, whole genome shotgun sequence.
ACCESSION   DARYUW010000160 DARYUW010000000
VERSION     DARYUW010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.162"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>574
                     /locus_tag="TVW11_002035"
     CDS             <1..>574
                     /locus_tag="TVW11_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1366084.1"
                     /translation="VPKLKNMLTYDEICDNTLKIKNLSCCYGEKIVFKNLNLSIRSGE
                     ILGIIGNNGVGKTTLLRCIAGLHKETKGEITLNGDVISGKKRQRLSAMVMQDVNYQLF
                     ADSLVEECCLGNNCDNIQIDKVLGELKLIESKKSHPMILSGGQKQRLVVANAILSDKK
                     ILIFDEPTSGLDYEGMLAVSNELKKLSEKNY"
BASE COUNT          230 a           54 c          115 g          175 t
ORIGIN      
        1 ggtaccgaag ttaaaaaata tgcttactta tgatgaaata tgtgataata cgttaaaaat
       61 taagaatttg tcttgttgtt atggagaaaa aatagttttt aaaaatttaa atctaagcat
      121 aagatctgga gaaatattag gaattatagg aaataacggt gttggaaaga ctacacttct
      181 tcgatgtatt gcaggattac ataaagaaac aaaaggagaa attacattaa atggtgatgt
      241 tataagtggc aaaaaaagac aaaggctatc tgcaatggtt atgcaagatg tgaattatca
      301 gttatttgca gatagcttag tagaagaatg ttgcttagga aataactgtg ataatataca
      361 aattgataag gttttgggtg aactaaaatt aattgagtca aaaaaatcac atcctatgat
      421 actttccggt ggacaaaaac aaaggttagt agttgcaaat gcgattttat ctgataagaa
      481 aatattaatt tttgatgaac cgacatcagg attggattat gaaggtatgc ttgcagtgtc
      541 taatgaacta aagaagttga gtgaaaaaaa ttac
//
LOCUS       DARYUW010000161          539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.165, whole genome shotgun sequence.
ACCESSION   DARYUW010000161 DARYUW010000000
VERSION     DARYUW010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.165"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..>539)
                     /locus_tag="TVW11_002036"
     CDS             complement(<1..>539)
                     /locus_tag="TVW11_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366085.1"
                     /translation="TVFNAPSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYL
                     GDDELGISRWVDGKAGIGRHSLAAYRFNSKGQVIDRKGHPAAAQAPALATLRSRLTDY
                     RRLKKQYAASNGISSSEEFYLDQFQSRAVAQALEQTTQLAQEEIIARRKEAVAEAEAL
                     HQKTRDMPFFVSELSWAEL"
BASE COUNT          130 a          138 c          127 g          144 t
ORIGIN      
        1 tctagctccg cccagctcaa ttcactcaca aaaaagggca tgtctcttgt cttttggtga
       61 agtgcctctg cctctgcaac cgcctccttc cgacgagcaa tgatctcctc ttgggcaagc
      121 tgagtggtct gctccaaagc ctgtgcgact gctcgagact gaaattgatc aaggtaaaac
      181 tcctctgagc tactaatacc gttagaagcg gcatactgtt tcttaagccg gcgataatcg
      241 gttagtctgg atcttagggt agcaagagca ggtgcttgag cagcggcagg gtgaccctta
      301 cggtcaatca cctgcccctt tgagttgaag cgataagcgg ctaagctatg acgtcctatt
      361 cccgccttac catcaaccca tcttgaaatc ccgagctcat catctccaag gtaagtgcct
      421 aggtttccaa tgtagtcatt gttaatgcgg tagctgtgat agagtccctt gttggcttta
      481 acaaagtcaa tagcctcctt ggagaggtta ttaacagagc ttggcgcatt aaagacagt
//
LOCUS       DARYUW010000162          537 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.166, whole genome shotgun sequence.
ACCESSION   DARYUW010000162 DARYUW010000000
VERSION     DARYUW010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..537
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.166"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..>537)
                     /locus_tag="TVW11_002037"
     CDS             complement(<1..>537)
                     /locus_tag="TVW11_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL1366086.1"
                     /translation="DQKIVRFKGFEDINDRDLRVGTFYYPKNEEKKHLILLVCGYEES
                     YLDFKSEIFFWLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNETFK
                     KVSLVGHSMGGFAVATSLQFKTNIIDNSVIISGFDYPSEFVRKSVTNISFIFTWPIEI
                     SIKLIEFLKFGNLSFLGSV"
BASE COUNT          187 a          109 c           53 g          188 t
ORIGIN      
        1 aactgatccc aaaaaagaca ggttcccaaa tttcaaaaat tctataagtt ttatggatat
       61 ttctattggc catgtaaaaa taaacgaaat atttgttaca ctttttctta caaattcaga
      121 tggataatca aatcctgaaa tgattacact gttatctatt atattggttt tgaattgtaa
      181 cgaagtcgct actgcaaaac ctcccatact atgccccact aaagatacct ttttaaaagt
      241 ttcatttttt tcaatgtatt caatggacaa taagcaatcc ttcaaaaact gagtaaaacc
      301 tccaactttt cttccctgac ttcttccagt tcctctaaca tcatagcaaa acacagtata
      361 tccatttttc agccaaaaaa atatctcgga tttaaagtct aaataggatt cttcatatcc
      421 acaaactagt aatatcaaat gtttcttttc ttcattcttg ggataataaa atgtccctac
      481 tctcaaatca cgatcattaa tatcttcaaa tcccttaaat ctaactattt tttgatc
//
LOCUS       DARYUW010000163          533 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.167, whole genome shotgun sequence.
ACCESSION   DARYUW010000163 DARYUW010000000
VERSION     DARYUW010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.167"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..>533)
                     /locus_tag="TVW11_002038"
     CDS             complement(<1..>533)
                     /locus_tag="TVW11_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1366087.1"
                     /translation="VIVDLASMVTSVVAIVLIEWRLALVFLLLSIVTVFLSQIPGKLM
                     SKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNTTLEFEDSRQKYQYR
                     KDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLLNGVFGPLQSFLYNK
                     NLIKSTGTILTSIQEVL"
BASE COUNT          191 a           93 c           71 g          178 t
ORIGIN      
        1 tagaacttct tgaatacttg ttaaaatagt acctgtgctt ttgatcaaat ttttattgta
       61 aaggaaagac tgtagagggc caaacactcc atttaataac tgaatactgg ccactaatag
      121 tccaactgtt agtagattat tccttacaaa aaatatacca gcaaccatac aggctacttg
      181 agaaaagaag ctcaaaaaca ttcctgtatt tgaagctaaa tcttttctgt attgatattt
      241 ctgtctagaa tcttcaaatt ctaaagtagt attttgttcg attttttgta tccatttttg
      301 aatattcaat aatttaatct gttcaaatcc ctcaataaaa ctagtcattt ctgctaaata
      361 gtgattactt ttttcagaat aatatcgagt tgctttactc attaactttc caggaatttg
      421 agatagaaaa acagttacaa tagaaagcaa taaaaatact agggccaatc gccattctat
      481 aagtacaata gctactacac tcgtaaccat tgaagccaga tcaacaatca cag
//
LOCUS       DARYUW010000164          513 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.168, whole genome shotgun sequence.
ACCESSION   DARYUW010000164 DARYUW010000000
VERSION     DARYUW010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.168"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>513
                     /locus_tag="TVW11_002039"
     CDS             <1..>513
                     /locus_tag="TVW11_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1366088.1"
                     /translation="RFSRDYILLGDYLSNILPFLKIRFIAINDNYDSINEDGNGIDTD
                     IQFKTLYYDLFSKELSEKVKSSFKQLKSQGKNTNWAAPFGYIKDPKDKHHIILDEKTA
                     FIVKEAFDLLLEGYSCNQVANIFNEKDYITCSERKEELKISEYTRNLVTGSKINKRVW
                     TSATISRITSN"
BASE COUNT          207 a           61 c           92 g          153 t
ORIGIN      
        1 agattttcaa gagattatat attgcttgga gactatctga gtaatatatt gccctttttg
       61 aaaatacggt ttattgctat caatgataac tatgattcga taaacgaaga tggaaacggg
      121 atagatacag atatacagtt taagaccttg tattatgatt tattcagtaa ggaattatcg
      181 gaaaaagtaa aaagttcttt taaacaactc aaatcacagg gcaagaatac aaattgggca
      241 gcaccttttg gatatataaa agatccaaaa gataaacatc atattatact tgatgaaaag
      301 acagctttta tagtgaaaga agcttttgac ttgctgttag agggatattc ttgcaatcag
      361 gtagcaaata tattcaatga aaaagattat ataacctgtt ctgaaagaaa agaagaacta
      421 aaaatttcag agtatacaag aaatcttgtt actggtagta aaataaataa aagagtttgg
      481 acaagtgcga ctatatccag aataacgagt aat
//
LOCUS       DARYUW010000165          497 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.169, whole genome shotgun sequence.
ACCESSION   DARYUW010000165 DARYUW010000000
VERSION     DARYUW010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.169"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>497
                     /locus_tag="TVW11_002040"
     CDS             <1..>497
                     /locus_tag="TVW11_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366089.1"
                     /translation="WIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDN
                     QSVFSFDSGKRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYE
                     SLKDIIEETESEPFILYISSVYDDIVSRIDEYKMEASIYVIGLVLSIVILATLLKIDK
                     ETYFY"
BASE COUNT          193 a           59 c           91 g          154 t
ORIGIN      
        1 gtggattgtt tttgttccag aagatgttaa aattactgaa cttgacaaag aaaaaattca
       61 cgaagatcat atttttcaaa atataaaaaa acaaggtaca attatagaaa catatgtaag
      121 gctgaaagat aatcaaagtg tattttcttt tgatagtggc aaaagaattg atgaagcaaa
      181 cttgaaaaat tatgttttgg tagcagtaaa tgggaaagaa ttactcccag atcacggaat
      241 caaactatca tctttagtaa atgggcagct acatccatat gttaaagagc ctagtagggc
      301 atacgagagt ttgaaggaca taattgaaga aacagaatct gagccgttta tactctatat
      361 cagctcagtt tacgatgata tagtttcaag aatagacgaa tataagatgg aggcaagtat
      421 atatgttatt ggtctcgtct tatctattgt tattttagca acgttattaa aaatagataa
      481 agaaacatat ttttata
//
LOCUS       DARYUW010000166          474 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.170, whole genome shotgun sequence.
ACCESSION   DARYUW010000166 DARYUW010000000
VERSION     DARYUW010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.170"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>474
                     /locus_tag="TVW11_002041"
     CDS             <1..>474
                     /locus_tag="TVW11_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL1366090.1"
                     /translation="ILKDTTEIKENYKYIGEESCCDILSINIGKTEVIIKAFNEMGRK
                     NLDTDMRMLFSMTVGYASGRLTLSSPLGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSK
                     PWLSILYEGDTYYKSYVYRNIWVEAIMDDLKEFVFEDKSKKQSNSMKIQHQLETSI"
BASE COUNT          181 a           51 c           92 g          150 t
ORIGIN      
        1 atattgaaag atactacaga aataaaagaa aattataaat acatagggga agagtcttgt
       61 tgtgacattt tatctataaa tattggtaaa acagaggtta ttataaaggc atttaatgaa
      121 atgggtagga aaaatttaga tacggatatg cgtatgcttt tttctatgac tgtgggatat
      181 gcgtctggta ggctaacttt atcaagtcct cttggaccag ttttatggga acaatcacct
      241 aatgtaccta aaatagatct tataccaaga tttttagacg gcaatgataa tgaaggatgt
      301 agtaaacctt ggttatcaat tctttatgag ggagatacat attataaatc atatgtatat
      361 agaaatattt gggttgaagc aataatggac gatttgaaag agttcgtttt tgaggacaaa
      421 agtaaaaaac aaagtaatag tatgaaaatt caacaccaat tggaaacttc tata
//
LOCUS       DARYUW010000167          468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.171, whole genome shotgun sequence.
ACCESSION   DARYUW010000167 DARYUW010000000
VERSION     DARYUW010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.171"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>468
                     /locus_tag="TVW11_002042"
     CDS             <1..>468
                     /locus_tag="TVW11_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1366091.1"
                     /translation="GKSTILMMIKDEILKHVPDEQKIYINFESLEFMSINEASFLASY
                     ISEKSKNLSGKLYYFFDEIQLVNNWEKVVNGLRVDQDCDIYITGSNSNLISGELATLL
                     AGRYIEFEIQPFTFGEFLKIFSDSNLTKEALFDKFIKLGGMPILKYFKLEEDS"
BASE COUNT          175 a           45 c           88 g          160 t
ORIGIN      
        1 ttggaaaatc taccattctg atgatgatta aagatgaaat tttgaaacat gtgccggatg
       61 agcaaaagat atatatcaat tttgaatctt tggagtttat gagtataaat gaagcgagct
      121 ttttggcaag ttatataagt gaaaagtcaa aaaatctaag tggtaaatta tattatttct
      181 ttgatgaaat acagttggta aataactggg aaaaagtagt taatgggtta agagtagatc
      241 aagattgtga tatatacatt accggttcaa attcaaattt gatttccggt gaacttgcca
      301 cacttcttgc aggaagatat atagaatttg aaatacagcc atttactttt ggggaatttt
      361 taaagatttt tagtgattca aatctaacta aagaagcact ttttgataaa tttataaaat
      421 taggtggaat gccgatttta aaatatttta agttagaaga agatagca
//
LOCUS       DARYUW010000168          465 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.173, whole genome shotgun sequence.
ACCESSION   DARYUW010000168 DARYUW010000000
VERSION     DARYUW010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.173"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..374
                     /locus_tag="TVW11_002043"
     CDS             <1..374
                     /locus_tag="TVW11_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1366092.1"
                     /translation="QGKAIVFVVSKDGIIAKSGEIDLKENKEVSIREIKEGEISLDIA
                     AQKTDIKISIPRLDDWKVSTDEKFIKGSYEANTDSQYTLYLLGKGGNLGISGTEMKGV
                     RVIVSWEKPKDKIDSWLVFND"
BASE COUNT          194 a           38 c           93 g          140 t
ORIGIN      
        1 aacaaggcaa agctattgtt tttgtagtat ctaaagatgg aatcatagca aagtcagggg
       61 aaatagattt aaaagaaaat aaagaagtaa gtataaggga aataaaagaa ggagaaatat
      121 ccttggatat agctgctcaa aaaacagata taaaaattag tattcctagg ttagatgatt
      181 ggaaagttag tacagatgaa aaatttatca agggctctta tgaagcaaat actgattcgc
      241 aatatacatt atatttatta ggaaaaggcg gaaatttagg catttccggt acggagatga
      301 aaggagtacg tgttattgta agttgggaaa aaccaaaaga taaaatagat agttggcttg
      361 tatttaatga ttaaaaatac aatatttgta ataaaagttg taaaataata atttattgtt
      421 aggggaggat ttatactaat gtgtaaatcc tcttttttat ataaa
//
LOCUS       DARYUW010000169          458 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.174, whole genome shotgun sequence.
ACCESSION   DARYUW010000169 DARYUW010000000
VERSION     DARYUW010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.174"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            <1..>458
                     /locus_tag="TVW11_002044"
     CDS             <1..>458
                     /locus_tag="TVW11_002044"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366093.1"
                     /translation="SPEFIKVVMRVDFERIVKAMRGYGVDEGDVQVVQRFRDTVINHI
                     LKAEDDYELEINKESIAYSLLILQKLVGITFGQVVSIIYLSFIKYLTQNSVKNAQFHF
                     GRLKGHIPDLTYTRPMIEYWKDYLEDGMSKKVMNAIGANEVLVEQFDVRA"
BASE COUNT          138 a           77 c          113 g          130 t
ORIGIN      
        1 agtcctgaat ttatcaaagt agttatgcgg gttgatttcg agcgcatcgt taaagccatg
       61 aggggttacg gtgttgatga aggtgacgtc caagttgtac aaagatttcg cgatacggtg
      121 atcaatcaca ttttgaaagc agaggatgat tatgagctag agataaataa agagagcatc
      181 gcttatagcc tgttgatcct gcaaaaatta gtaggtatta cattcggtca ggttgttagt
      241 atcatctacc tttcgtttat caagtacctg acccaaaatt cggtcaagaa tgctcaattc
      301 cacttcggca gattgaaagg gcatattcca gatttgacgt acactcgacc tatgatcgag
      361 tactggaaag actatcttga agatgggatg agtaagaaag ttatgaacgc cattggagca
      421 aatgaagtgt tggttgagca gttcgacgtt cgcgctaa
//
LOCUS       DARYUW010000170          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.175, whole genome shotgun sequence.
ACCESSION   DARYUW010000170 DARYUW010000000
VERSION     DARYUW010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.175"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(68..139)
                     /locus_tag="TVW11_002045"
     tRNA            complement(68..139)
                     /locus_tag="TVW11_002045"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYUW010000171          431 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.176, whole genome shotgun sequence.
ACCESSION   DARYUW010000171 DARYUW010000000
VERSION     DARYUW010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.176"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            9..>431
                     /locus_tag="TVW11_002046"
     CDS             9..>431
                     /locus_tag="TVW11_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL1366094.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGT"
BASE COUNT          173 a           47 c           86 g          125 t
ORIGIN      
        1 gggaggaggt gtttattatt aaaggtgaag tatccagaaa agatttgatt agagaaattg
       61 aaaaagctat taaaagtgat gaattaggag catttattgg agcaggatta tcaattcctg
      121 ccggattttg tagttggaaa gaacttctaa gagaacctgc agaagaaatt ggattagatg
      181 ttgaaaaaga aagtgatttg gttaacttgg ctcagtatta ttctaattca aaaaagagaa
      241 catcaataga tgacttgatc aaaggtcaat tttctcaatt agtaaagcct actgaaaatc
      301 ataaattatt gtcgcagctg cccatttcaa ctttttggac aacaaattat gataagttaa
      361 tagaaaaagc tttagaaaat aatatgaaaa agccttatgt aaaaacaaag gatgaacaat
      421 taagaggtac a
//
LOCUS       DARYUW010000172          399 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.178, whole genome shotgun sequence.
ACCESSION   DARYUW010000172 DARYUW010000000
VERSION     DARYUW010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.178"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
BASE COUNT          123 a           52 c           58 g          166 t
ORIGIN      
        1 tattgtttca acttttaata ggtcaatatg ctgatagaat aagaaataga gccaaatggt
       61 tgatttgggg aggaatctct cagtccatat tatttatgat aattgcttat ttaaccaatc
      121 agaaatcata cttagtattt tctataattt gtcttattaa tattatttct gattgtatat
      181 ctaatctatt atctgggatt tcgatgccaa tatttaagca ccatatccct caagatgaat
      241 taatgactgc ttactcgctt cgaaatatta tttccttcat ttgtgggata ggtggacaga
      301 tatttggtat ttggttactt gaaatttcaa ataaaaactt tggttttgtt gcaataataa
      361 atgctttttc ctttttaata tcatcaatta ttttagtat
//
LOCUS       DARYUW010000173          388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.179, whole genome shotgun sequence.
ACCESSION   DARYUW010000173 DARYUW010000000
VERSION     DARYUW010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.179"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(55..127)
                     /locus_tag="TVW11_002047"
     tRNA            complement(55..127)
                     /locus_tag="TVW11_002047"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92..94),aa:Thr,seq:tgt)
     gene            complement(135..216)
                     /locus_tag="TVW11_002048"
     tRNA            complement(135..216)
                     /locus_tag="TVW11_002048"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Leu,seq:tag)
     gene            complement(222..294)
                     /locus_tag="TVW11_002049"
     tRNA            complement(222..294)
                     /locus_tag="TVW11_002049"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(259..261),aa:Lys,seq:ttt)
     gene            complement(298..370)
                     /locus_tag="TVW11_002050"
     tRNA            complement(298..370)
                     /locus_tag="TVW11_002050"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Asp,seq:gtc)
BASE COUNT           98 a          119 c           85 g           86 t
ORIGIN      
        1 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcaactcta tcaatgccgg
       61 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      121 agccggccta tctatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      181 taaatctggt gcgtctgcca attccgccaa acccgccttt atgacccgta ctgggctcga
      241 accagtgacc ctttgattaa aagtcaaatg ctctaccaac tgagctaacg agtcctacgg
      301 tcccgacggg aatcgaaccc gcgatcttcg ccgtgacagg gcgacgtgat aaccgctaca
      361 ctacgggacc tattcataac ttatggga
//
LOCUS       DARYUW010000174          370 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.180, whole genome shotgun sequence.
ACCESSION   DARYUW010000174 DARYUW010000000
VERSION     DARYUW010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.180"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
BASE COUNT          145 a           62 c           48 g          115 t
ORIGIN      
        1 aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata acctagtgct
       61 tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa aaactgggat
      121 aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct ctattttttg
      181 aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag atgaacaatt
      241 tgttacactt gatttgatca tcggggctta gaaaaaatag tgaaaagaat cctcataatt
      301 cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta taagaagtag
      361 catgattaaa
//
LOCUS       DARYUW010000175          342 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.denovo.181, whole genome shotgun sequence.
ACCESSION   DARYUW010000175 DARYUW010000000
VERSION     DARYUW010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.denovo.181"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            complement(<1..>342)
                     /locus_tag="TVW11_002051"
     CDS             complement(<1..>342)
                     /locus_tag="TVW11_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1366095.1"
                     /translation="YHRSSFFIKTGSIVMVLYLAIVSILGLTDYLSMRQYIPTWESSK
                     YYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDDSGAILFNAPNVRKEGMNDDEE
                     YLNQQPFQGNY"
BASE COUNT          113 a           71 c           41 g          117 t
ORIGIN      
        1 cataattacc ttgaaaaggt tgttgattta gatactcctc atcatcattc attccctctt
       61 ttctaacgtt tggggcatta aataatattg ctccactatc gtccaaacta ttccataagt
      121 tattcagctt tggaataaca atttcatgga acttatcatc atctttttca taactccaag
      181 accatgcaca agccatattt gcataatact ttgagctttc ccaagttgga atgtattgtc
      241 tcatactcaa gtaatcagtg agtcctaaaa tacttacaat tgctagataa agaaccataa
      301 caatcgaccc tgtttttata aaaaaagaac ttctatgata ac
//
LOCUS       DARYUW010000176         1896 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611881-rid16722413.guided.123, whole genome shotgun sequence.
ACCESSION   DARYUW010000176 DARYUW010000000
VERSION     DARYUW010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611881
            Sequence Read Archive: SRR18311167
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574896.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574896.1
            Genome Coverage       :: 80x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:40:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,052
            CDSs (total)                      :: 2,017
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 32 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 28 of 80
            Pseudo Genes (multiple problems)  :: 8 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1896
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611881-rid16722413.guided.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: IN"
                     /collection_date="2019-12-17"
                     /collected_by="Purdue University Animal Disease Diagnostic
                     Laboratory, West Lafayette, IN"
     gene            43..1764
                     /locus_tag="TVW11_002052"
     CDS             43..1764
                     /locus_tag="TVW11_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1366096.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
BASE COUNT          523 a          329 c          463 g          581 t
ORIGIN      
        1 taagacagct tgaaataggt tagttcagaa atggaggata tgatgctgac cttaattgtt
       61 caacatatta agcaaaagaa atggatttat atccttattg caatgacttt agtgatatat
      121 gatgcctcac ttgtgatacc aacaagggtt attcaagact tggttgattt gatgtcaagg
      181 catcagctaa gctcaggggc attggtgagg catgttatca ttcttttggc tacggcagta
      241 gtgtcttatg gggttgctta tttgtggcat cttcatttat ttcaggaggc agttcatttt
      301 aagtttgata ttcagcagcg tgcctttcga aagcttgttt ttatgagaac gcctttttat
      361 gagaaatttc gctcaggtga catgatcacg cgtttttcaa cagatgtcga agcacttatg
      421 gaccttatcg gctatggctt gatgattatc ctatatgctg gtggtatgat tgcttttatt
      481 attccgacca tgtttttgat ttcttggaaa atgaccttga taggaatagt accgattttg
      541 cttatgatgg tgatgatcta tggtgtgacg aaaaagcaag agcatttggt tgaagaggcg
      601 cgtgaggcga tttcaagcct tagtgatgag gtactagaaa ccgttgaggg cattagagtg
      661 atgcgtgctt acagtaaaaa agattatttg gcacttcatt ttgctcaaaa gactcagaat
      721 ttggcagata aatggaatca ggtggccaag tatcgtgcct tgtactttcc tctttacagc
      781 gtcatgattg ccattagtac agtaatcatt ttaatggtag gcctacagct catagcaagc
      841 tcagaggtaa cacttggtca agtcattgcg ctgcagcttt atctggtgtc tttggtggag
      901 ccctttggca tgctgtcaga ctttattttg gtttatcaga caggaaagac ctcttttggt
      961 aagattaatg aactcatcga aacaagtgat gatatggagc ctgatggcca gcttgagtta
     1021 gagagctttg atcagattgc ttttatagac tatagcttta cctatgccaa tagttctagg
     1081 cctagcttag aaaagatcaa tttaaccctg aaaaagggac aaaccttagg gattgttggt
     1141 aaaacaggct ctggtaaaac aacccttgtc aggcagtttt tgagacaata ccctcttggg
     1201 caggggcagc tgatgattaa tcatcgtagt gtcttggatt ataagcgtca atcacttgag
     1261 cgtcaaattg gctatgtgcc acaggagcat atcctgtttt caaaaacggt tgctcaaaac
     1321 attgcgatgg ggaaaaaggc agctacaact gaggaaatct tggaggcgat tgaaactgcg
     1381 gcctttacgc gtgatgttca aggaatggca aagggcttgg atactgagat tggagagcgt
     1441 ggtctgtcta tttcaggagg tcaaaagcag cgtatttcga ttgccagagc ctttttgtcc
     1501 cagccagatt tgctgatttt agatgattcc ctgtcggcag ttgatgctag aacagagact
     1561 gatattattc gacacattca agacgaaaga aagggaaaga caacacttat tgttagccat
     1621 cgcttgtctg cgattcagca tgccgattgg gttattgttc tggatcaggg gcagatagta
     1681 gaggaaggtc agccccaaca acttttagct cagaagggct ggtattatga acagtaccag
     1741 cgtcagcagg ctcaggaggt ttaagatgac cctatttata aaattaataa aagaaattaa
     1801 agctgtgacc ttggcttttt ccctggcaat aggctttttg ctagtggcaa cagctggagg
     1861 tcagatggct cccttattgt tgcaacaaac gattga
//
